valproic acid and primidone

valproic acid has been researched along with primidone in 139 studies

Research

Studies (139)

Timeframe	Studies, this research(%)	All Research%
pre-1990	92 (66.19)	18.7374
1990's	23 (16.55)	18.2507
2000's	13 (9.35)	29.6817
2010's	10 (7.19)	24.3611
2020's	1 (0.72)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Bruno-Blanch, L; Gálvez, J; García-Domenech, R	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y	1
Bohlen, N; Hertl, M	1
Roger, J; Tassinari, CA	1
Richens, A	1
Buchthal, A	1
Egli, M	1
Dreifuss, FE	2
Fichsel, H; Knöpfle, G	1
Penin, H	1
Loiseau, P	1
Goujet, MA; Simon, P	1
Livingston, S; Pauli, LL; Pruce, I	1
Sauer, W; Windorfer, A	1
Stünkel, S; Weinmann, HM; Windorfer, A	1
Klotz, U	1
Helenius, T; Liewendahl, K; Majuri, H	1
Mimaya, H	1
Conomy, JP	1
Göbel, W; Löscher, W	1
Bruni, J	3
Newmark, ME; Penry, JK	1
Reith, H; Schäfer, H	1
Crawford, RD; Davis, HL; Johnson, DD	1
Deisenhammer, E; Sommer, R	1
Hosokawa, K; Kugoh, T; Otsuki, S	1
Brachet, A; Henry, P; Loiseau, P	1
Dam, M; Hvidberg, EF	1
Coulthard, MG	1
Gädeke, R; Sauer, W; Windorfer, A	1
Watanabe, M; Yagi, K	1
Müller, D; Todt, H	1
Benedetti, TJ; Erickson, DM; Leavitt, A; Loewenson, RB; McCormick, KB; Sells, CJ; Yerby, MS	1
Burlina, A; Mould, GP; Müller, C; Stamp, RJ	1
Eadie, MJ	1
Modica, PA; Spitznagel, EL; Tempelhoff, R	1
Matisová, E; Pham Thi, Ha; Volmut, J	1
Bausch, S; Blackwood, J; Gassmann, S; Grün, K; Inbar, S; Kreider, R; Löchel, B; Siebert, M; Walter, G	1
Ruser, I	1
Artieda, J; Day, B; Marsden, CD; Obeso, JA; Rothwell, JC; Thompson, P	1
Aoyama, T; Higuchi, S; Yukawa, E	1
Armijo Simón, JA; Arteaga Manjón-Cabeza, R; Herranz Fernández, JL	1
Macdonald, RL; McLean, MJ	1
Hartshorn, EA; Hartshorn, JC	1
Berry, DJ; Newbery, JE; Pettit, LI; Streete, JM	1
Baciewicz, AM	1
Shinnar, S	1
Bourgeois, BF	1
Hobusch, D; Popp, K; Rohmann, E; Schwebke, D; Sengbusch, S	1
Levy, RH; Yerby, MS	1
Ishizaki, T; Kushida, K	1
Burke, JT; Thénot, JP	1
Canevini, MP; Canger, R; Cornaggia, C; Giuccioli, D; Pinelli, P; Pruneri, C	1
Frey, HH; Löscher, W	1
Tollefson, G	1
Maheshwari, MC	1
Bruni, J; Wilder, BJ	1
Schmidt, D	3
Deisenhammer, E; Schwarzbach, H; Sommer, R	1
Neuvonen, PJ; Tokola, RA	1
Hosokawa, K; Kugoh, T	1
Monninger, P; Przuntek, H	1
Berlit, P; Krause, KH; Rascher, W	1
Hobusch, D; Külz, J	2
Kiul'ts, I; Klaĭf, F	1
Göpfert-Geyer, I; Hartmann, A; Helge, H; Huth, H; Jäger-Roman, E; Jakob, S; Koch, S; Rating, D	1
Rowan, AJ	1
Crema, A; Perucca, E	1
Friis, ML	1
Hvidberg, EF	1
Armijo, JA; Arteaga, R; Herranz, JL	1
Callaghan, N; Keating, J; O'Dwyer, R	1
Albright, PS; Bruni, J	1
Knott, C; Reynolds, F	1
Helge, H; Jäger-Roman, E; Kuhnz, W; Nau, H; Rating, D	1
Kutt, H	1
Hedges, A; Makki, KA; Perucca, E; Richens, A; Ruprah, M; Wilson, JF	1
Alonso, RJ; Covington, TR; Mancall, EL	1
De Paiva, VJ; Subirana, A; Subirana, M	1
Forsythe, WI; Sills, MA	1
Deisenhammer, E; Nitsche, V; Sommer, R	1
Marghescu, S; Neukam, D	1
Franco-Morselli, R; Morselli, PL	1
Kirkham, DB; Reynolds, NC	1
Kingsley, E; Tolman, KG; Tweedale, R	1
Quednow, B; Walther, H	1
Aminoff, MJ	1
Kulik, FA; Wilbur, R	1
Scollo-Lavizzari, G	1
Minagawa, K; Miura, H	1
Majkowski, J; Pisarski, W; Tokarz, A; Woźniak, J	1
Goodey, RJ	1
Cohan, SL	1
Koch, KM; Levy, RH	1
Congdon, WC; DuCharme, LL; Levy, RH; Lockard, JS	1
Kido, H	1
Cloyd, J; Garnett, WR; Holmes, GL; Meyer, MC; Schiffer, JR	1
Hekster, YA; Keyser, A; Lammers, MW; Meinardi, H; Renier, WO; van Lier, H; Wijsman, DJ	1
Avanzini, G; Battino, D; Estienne, M	1
Helge, H; Jäger-Roman, E; Koch, S; Lösche, G; Nau, H; Rating, D	1
Perucca, E; Pisani, F; Spina, E	1
Ferrera, PC; Thibodeau, LG	1
Luer, MS; Winkler, SR	1
Boothe, DM	1
Bates, D; Privitera, M; Warner, A	1
Booij, LH; Driessen, JJ; Robertson, EN; Vree, TB	1
Cavazzuti, GB	1
Chadwick, D	1
Fukuhara, N; Ishida, C	1
Caretto, J; Schaffer, CB; Schaffer, LC	1
Apeland, T; Kristensen, O; Mansoor, MA; Strandjord, RE	1
Knudsen, FU	1
Laskowska, M; Leszczyńska-Gorzelak, B; Oleszczuk, J	1
Meencke, HJ; Paul, F	1
Dahl, ML; Kimland, E; Tomson, T	1
Edelbroek, PM; Vermeij, TA	1
Apeland, T; Frøyland, ES; Kristensen, O; Mansoor, MA; Strandjord, RE	1
Deckers, CL; Liu, YX; Sun, MZ; Wang, W	1
Klapková, E; Komárek, V; Tesfaye, H; Tesfayeová, A	1
Bialer, M	1
Beydemir, Ş; Demir, Y	1
de Baat, C; Vissink, A; Zweers, PGMA	1
Ashikawa, H; Honda, T; Mogi, H; Murayama, T; Nakamura, H	1

Reviews

34 review(s) available for valproic acid and primidone

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Interactions with antiepileptic drugs. Drugs, 1977, Volume: 13, Issue:4 Topics: Acetaminophen; Acetazolamide; Anti-Anxiety Agents; Anticoagulants; Anticonvulsants; Carbamazepine; Diazepam; Drug Interactions; Furosemide; Gonadal Steroid Hormones; Griseofulvin; Humans; Phenobarbital; Phenytoin; Primidone; Thiazines; Urea; Valproic Acid; Vitamin D	1977
[Pharmacotherapy of epilepsy. II]. Die Medizinische Welt, 1978, Jun-02, Volume: 29, Issue:22 Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anticonvulsants; Benzodiazepines; Carbamazepine; Epilepsy; Humans; Mephenytoin; Mephobarbital; Phenobarbital; Phenytoin; Primidone; Succinimides; Thiazines; Valproic Acid	1978
[Long-term anticonvulsant therapy (author's transl)]. Der Nervenarzt, 1978, Volume: 49, Issue:9 Topics: Anticonvulsants; Carbamazepine; Chronic Disease; Clonazepam; Epilepsy; Ethosuximide; Humans; Long-Term Care; Phenobarbital; Phenytoin; Primidone; Valproic Acid	1978
The medical treatment of epilepsy: initiation of drug therapy. Pediatric annals, 1979, Volume: 8, Issue:4 Topics: Adolescent; Adrenocorticotropic Hormone; Anticonvulsants; Bromides; Carbamazepine; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Epilepsy, Absence; Humans; Hydantoins; Phenobarbital; Phenytoin; Primidone; Valproic Acid	1979
[Laboratory controls in long-term treatment with anticonvulsive drugs (author's transl)]. Monatsschrift fur Kinderheilkunde, 1977, Volume: 125, Issue:3 Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clonazepam; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Intestinal Absorption; Male; Phenobarbital; Phenytoin; Primidone; Time Factors; Valproic Acid	1977
[Antiepileptics during pregnancy and lactation. Pharmacokinetic data]. Deutsche medizinische Wochenschrift (1946), 1979, Jun-01, Volume: 104, Issue:22 Topics: Anticonvulsants; Bromides; Carbamazepine; Clonazepam; Diazepam; Ethosuximide; Female; Fetus; Humans; Kinetics; Lactation; Maternal-Fetal Exchange; Nitrazepam; Phenobarbital; Phenytoin; Pregnancy; Primidone; Valproic Acid	1979
Pharmacological and biochemical studies in epileptic fowl. Federation proceedings, 1979, Volume: 38, Issue:10 Topics: Animals; Anticonvulsants; Benzodiazepinones; Brain; Chickens; Disease Models, Animal; Ethosuximide; Female; Humans; Male; Mutation; Phenobarbital; Phenytoin; Photic Stimulation; Primidone; Seizures; Valproic Acid	1979
Clinical pharmacokinetics of anticonvulsants. Clinical pharmacokinetics, 1976, Volume: 1, Issue:3 Topics: Administration, Oral; Adult; Aged; Aging; Animals; Anticonvulsants; Carbamazepine; Child; Clonazepam; Diazepam; Drug Interactions; Ethosuximide; Female; Humans; Hydantoins; Infant, Newborn; Injections, Intramuscular; Injections, Intravenous; Intestinal Absorption; Kidney Diseases; Kinetics; Liver Diseases; Milk; Molecular Biology; Phenobarbital; Phenytoin; Pregnancy; Primidone; Valproic Acid	1976
[Neurotoxicity of antiepileptic drugs]. No to shinkei = Brain and nerve, 1992, Volume: 44, Issue:12 Topics: Adult; Anticonvulsants; Benzodiazepines; Carbamazepine; Child; Ethosuximide; Humans; Male; Nervous System; Nervous System Diseases; Phenobarbital; Phenytoin; Primidone; Valproic Acid	1992
Formation of active metabolites of anticonvulsant drugs. A review of their pharmacokinetic and therapeutic significance. Clinical pharmacokinetics, 1991, Volume: 21, Issue:1 Topics: Anticonvulsants; Benzodiazepines; Biotransformation; Carbamazepine; Humans; Mephenytoin; Mephobarbital; Oxcarbazepine; Phenytoin; Primidone; Valproic Acid	1991
Anticonvulsant drugs: mechanisms of action. Advances in neurology, 1986, Volume: 44 Topics: Action Potentials; Animals; Anticonvulsants; Barbiturates; Benzodiazepines; Biomechanical Phenomena; Carbamazepine; gamma-Aminobutyric Acid; Humans; Neurotransmitter Agents; Phenytoin; Primidone; Succinimides; Synapses; Synaptic Transmission; Valproic Acid	1986
Carbamazepine drug interactions. Therapeutic drug monitoring, 1986, Volume: 8, Issue:3 Topics: Carbamazepine; Cimetidine; Dextropropoxyphene; Drug Interactions; Erythromycin; Humans; Isoniazid; Lithium; Phenobarbital; Phenytoin; Primidone; Protein Binding; Troleandomycin; Valproic Acid; Warfarin	1986
Antiepileptic drugs in adolescents. Journal of adolescent health care : official publication of the Society for Adolescent Medicine, 1987, Volume: 8, Issue:1 Topics: Adaptation, Psychological; Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Clonazepam; Drug Interactions; Epilepsy; Ethosuximide; Female; Humans; Phenobarbital; Phenytoin; Pregnancy; Primidone; Sports; Valproic Acid	1987
Determination of antiepileptic drugs. Journal of chromatography, 1985, May-10, Volume: 340 Topics: Anticonvulsants; Barbiturates; Carbamazepine; Chromatography, Gas; Chromatography, Liquid; Clonazepam; gamma-Aminobutyric Acid; Gas Chromatography-Mass Spectrometry; Humans; Mephenytoin; Monitoring, Physiologic; Phenytoin; Primidone; Succinimides; Valproic Acid	1985
Pharmacokinetics of anti-epileptic drugs in the dog: a review. Journal of veterinary pharmacology and therapeutics, 1985, Volume: 8, Issue:3 Topics: Animals; Anticonvulsants; Blood Proteins; Carbamazepine; Clonazepam; Diazepam; Dog Diseases; Dogs; Epilepsy; Ethosuximide; Kinetics; Phenobarbital; Phenytoin; Primidone; Species Specificity; Trimethadione; Valproic Acid	1985
[Anticonvulsants and their side effects. II. Side effects]. Kinderarztliche Praxis, 1980, Volume: 48, Issue:9 Topics: Adrenocorticotropic Hormone; Anticonvulsants; Barbiturates; Benzodiazepines; Carbamazepine; Humans; Phenytoin; Primidone; Succinimides; Valproic Acid	1980
Diagnosis and treatment of epilepsy. Hospital & community psychiatry, 1983, Volume: 34, Issue:6 Topics: Automatism; Benzodiazepines; Carbamazepine; Electroencephalography; Epilepsies, Partial; Epilepsy; Epilepsy, Temporal Lobe; Ethosuximide; Humans; Muscle Tonus; Phenobarbital; Phenytoin; Primidone; Telemetry; Valproic Acid	1983
The clinical pharmacology of antiepileptic drugs. Clinical neuropharmacology, 1984, Volume: 7, Issue:1 Topics: Adult; Anticonvulsants; Benzodiazepines; Carbamazepine; Drug Interactions; Ethosuximide; Female; Half-Life; Humans; Intestinal Absorption; Kidney; Kidney Diseases; Kinetics; Liver Diseases; Phenobarbital; Phenytoin; Pregnancy; Primidone; Protein Binding; Tissue Distribution; Trimethadione; Valproic Acid	1984
Interactions between anticonvulsants and other commonly prescribed drugs. Epilepsia, 1984, Volume: 25 Suppl 2 Topics: Analgesics; Anti-Infective Agents; Anticoagulants; Anticonvulsants; Benzodiazepines; Biotransformation; Carbamazepine; Drug Interactions; Humans; Intestinal Absorption; Kinetics; Phenobarbital; Phenytoin; Primidone; Protein Binding; Psychotropic Drugs; Succinimides; Sulfonamides; Tissue Distribution; Valproic Acid	1984
Clinical pharmacokinetics of antiepileptic drugs in adults. Pharmacology & therapeutics, 1980, Volume: 10, Issue:1 Topics: Adult; Aging; Anticonvulsants; Carbamazepine; Clonazepam; Diazepam; Disease; Ethosuximide; Female; Humans; Kinetics; Phenobarbital; Phenytoin; Pregnancy; Primidone; Saliva; Valproic Acid	1980
Anticonvulsant drugs in alcohol withdrawal: use of phenytoin, primidone, carbamazepine, valproic acid, and the sedative anticonvulsants. American journal of hospital pharmacy, 1981, Volume: 38, Issue:8 Topics: Alcoholism; Anticonvulsants; Carbamazepine; Humans; Hypnotics and Sedatives; Phenytoin; Primidone; Status Epilepticus; Substance Withdrawal Syndrome; Valproic Acid	1981
Pharmacological principles in the long-term treatment of epilepsy. European neurology, 1981, Volume: 20, Issue:4 Topics: Anticonvulsants; Carbamazepine; Clonazepam; Diazepam; Epilepsy; Ethosuximide; Humans; Kinetics; Long-Term Care; Phenobarbital; Phenytoin; Primidone; Succinimides; Valproic Acid	1981
Antiepileptic therapeutic drug monitoring. Clinics in laboratory medicine, 1981, Volume: 1, Issue:3 Topics: Anticonvulsants; Carbamazepine; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid	1981
Drug interactions with valproic acid. Drugs, 1982, Volume: 24, Issue:6 Topics: Anticonvulsants; Carbamazepine; Clonazepam; Dose-Response Relationship, Drug; Drug Interactions; Ethosuximide; Fatty Acids, Nonesterified; Humans; Kinetics; Phenobarbital; Phenytoin; Primidone; Salicylates; Valproic Acid	1982
Clinical pharmacokinetics of antiepileptic drugs in paediatric patients. Part I: Phenobarbital, primidone, valproic acid, ethosuximide and mesuximide. Clinical pharmacokinetics, 1995, Volume: 29, Issue:4 Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Epilepsy; Ethosuximide; Humans; Infant; Infant, Newborn; Phenobarbital; Primidone; Succinimides; Valproic Acid	1995
Clinically significant pharmacokinetic drug interactions with carbamazepine. An update. Clinical pharmacokinetics, 1996, Volume: 31, Issue:3 Topics: Analgesics, Non-Narcotic; Anti-Bacterial Agents; Anticonvulsants; Antidepressive Agents; Carbamazepine; Drug Interactions; Ethosuximide; Felbamate; Humans; Phenobarbital; Phenylcarbamates; Phenytoin; Primidone; Propylene Glycols; Valproic Acid	1996
Antiepileptic drug review: part 1. Surgical neurology, 1998, Volume: 49, Issue:4 Topics: Anticonvulsants; Biological Availability; Carbamazepine; Drug Interactions; Half-Life; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid	1998
Anticonvulsant therapy in small animals. The Veterinary clinics of North America. Small animal practice, 1998, Volume: 28, Issue:2 Topics: Acetates; Amines; Animals; Anticonvulsants; Bromides; Clonazepam; Clorazepate Dipotassium; Cyclohexanecarboxylic Acids; Diazepam; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Mephenytoin; Pentobarbital; Phenobarbital; Phenylcarbamates; Phenytoin; Primidone; Propylene Glycols; Seizures; Valproic Acid	1998
Standards of laboratory practice: antiepileptic drug monitoring. National Academy of Clinical Biochemistry. Clinical chemistry, 1998, Volume: 44, Issue:5 Topics: Anticonvulsants; Blood Specimen Collection; Carbamazepine; Drug Interactions; Drug Monitoring; Humans; Phenobarbital; Phenytoin; Primidone; Quality Control; Valproic Acid	1998
[Neurotoxicity of anticonvulsants]. Ryoikibetsu shokogun shirizu, 1999, Issue:27 Pt 2 Topics: Anticonvulsants; Carbamazepine; Ethosuximide; Humans; Phenytoin; Primidone; Valproic Acid	1999
[Febrile convulsions, Treatment and prognosis]. Ugeskrift for laeger, 2001, Feb-19, Volume: 163, Issue:8 Topics: Analgesics, Non-Narcotic; Anticonvulsants; Child, Preschool; Diazepam; Epilepsy; Humans; Infant; Phenobarbital; Primidone; Prognosis; Recurrence; Seizures, Febrile; Time Factors; Valproic Acid	2001
Therapeutic monitoring of antiepileptic drugs for epilepsy. The Cochrane database of systematic reviews, 2007, Jan-24, Issue:1 Topics: Anticonvulsants; Carbamazepine; Drug Monitoring; Epilepsy; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid	2007
[Medicaments and oral healthcare. Proliferation of the gingiva]. Nederlands tijdschrift voor tandheelkunde, 2018, Volume: 125, Issue:7-8 Topics: Anticonvulsants; Carbamazepine; Cell Proliferation; Ethosuximide; Gingiva; Humans; Netherlands; Oral Hygiene; Phenobarbital; Phenytoin; Primidone; Valproic Acid	2018

Trials

9 trial(s) available for valproic acid and primidone

Article	Year
[Clinical and experimental control of optimal therapy in epilepsy]. Psychiatrie, Neurologie, und medizinische Psychologie, 1990, Volume: 42, Issue:9 Topics: Anticonvulsants; Carbamazepine; Drug Therapy, Combination; Epilepsy; Humans; Neurocognitive Disorders; Neuropsychological Tests; Phenytoin; Primidone; Substance-Related Disorders; Valproic Acid	1990
[Anti-epileptic agents during pregnancy. A prospective study on the course of pregnancy, malformations and child development]. Deutsche medizinische Wochenschrift (1946), 1983, Feb-18, Volume: 108, Issue:7 Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Adult; Akathisia, Drug-Induced; Anencephaly; Anticonvulsants; Craniofacial Dysostosis; Epilepsy; Female; Fetal Growth Retardation; Humans; Infant; Infant, Low Birth Weight; Infant, Newborn; Infant, Newborn, Diseases; Maternal-Fetal Exchange; Phenytoin; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Primidone; Substance Withdrawal Syndrome; Uterine Cervical Incompetence; Valproic Acid	1983
Antiepileptic drug treatment in pregnancy: drug side effects in the neonate and neurological outcome. Acta paediatrica (Oslo, Norway : 1992), 1996, Volume: 85, Issue:6 Topics: Anticonvulsants; Child; Drug Monitoring; Epilepsy; Female; Follow-Up Studies; Humans; Nervous System Diseases; Neurologic Examination; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Primidone; Valproic Acid	1996
Outcome evaluation of gabapentin as add-on therapy for partial seizures. "NEON" Study Investigators Group. Neurontin Evaluation of Outcomes in Neurological Practice. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 1998, Volume: 25, Issue:2 Topics: Acetates; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Carbamazepine; Clobazam; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neurologic Examination; Phenobarbital; Phenytoin; Primidone; Quality of Life; Valproic Acid	1998
Prevention of febrile convulsions with dipropylacetate (Depakine). Epilepsia, 1975, Volume: 16, Issue:4 Topics: Anticonvulsants; Child, Preschool; Humans; Phenobarbital; Primidone; Seizures, Febrile; Valproic Acid	1975
Does withdrawal of different antiepileptic drugs have different effects on seizure recurrence? Further results from the MRC Antiepileptic Drug Withdrawal Study. Brain : a journal of neurology, 1999, Volume: 122 ( Pt 3) Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Drug Combinations; Epilepsy; Female; Humans; Male; Phenobarbital; Phenytoin; Primidone; Proportional Hazards Models; Recurrence; Risk Assessment; Seizures; Substance Withdrawal Syndrome; Valproic Acid	1999
The use of primidone in the treatment of refractory bipolar disorder. Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists, 1999, Volume: 11, Issue:2 Topics: Adult; Ambulatory Care; Anticonvulsants; Antipsychotic Agents; Bipolar Disorder; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Lithium; Male; Middle Aged; Primidone; Prospective Studies; Treatment Failure; Treatment Outcome; Valproic Acid	1999
[Evaluation of antiepileptic therapy during pregnancy]. Ginekologia polska, 2002, Volume: 73, Issue:1 Topics: Adult; Anticonvulsants; Apgar Score; Drug Therapy, Combination; Epilepsy; Female; Humans; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Primidone; Valproic Acid	2002
Comparison of add-on valproate and primidone in carbamazepine-unresponsive patients with partial epilepsy. Seizure, 2009, Volume: 18, Issue:2 Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Drug Therapy, Combination; Epilepsies, Partial; Female; Humans; Male; Middle Aged; Primidone; Seizures; Valproic Acid	2009

Other Studies

96 other study(ies) available for valproic acid and primidone

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity. Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16 Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship	2003
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships. Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16 Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone	2016
[Adverse effects of anti-epileptic drugs]. Deutsche medizinische Wochenschrift (1946), 1975, Sep-19, Volume: 100, Issue:38 Topics: Adrenocorticotropic Hormone; Anticonvulsants; Barbiturates; Carbamazepine; Diazepam; Epilepsy; Ethosuximide; Humans; Mephenytoin; Nitrazepam; Phenytoin; Primidone; Succinimides; Thiazines; Trimethadione; Valproic Acid	1975
Prognosis and therapy of complex partial seizures with barbiturates, hydantoins, and other drugs. Advances in neurology, 1975, Volume: 11 Topics: Anticonvulsants; Barbiturates; Benzodiazepines; Drug Therapy, Combination; Epilepsy; Epilepsy, Temporal Lobe; Hydantoins; Mephenytoin; Phenobarbital; Phenytoin; Primidone; Prognosis; Succinimides; Thiazines; Valproic Acid	1975
[Drug interactions in antiepileptic combination therapy]. Deutsche medizinische Wochenschrift (1946), 1979, Feb-16, Volume: 104, Issue:7 Topics: Anticonvulsants; Carbamazepine; Drug Interactions; Drug Therapy, Combination; Enzyme Induction; Humans; Phenobarbital; Phenylbutyrates; Phenytoin; Primidone; Thiazines; Time Factors; Urea; Valproic Acid	1979
Use of anticonvulsant drugs. JAMA, 1979, Feb-09, Volume: 241, Issue:6 Topics: Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid	1979
Effects of anticonvulsant drugs on thyroid hormones in epileptic children. Epilepsia, 1978, Volume: 19, Issue:4 Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Cholesterol; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsy; Humans; Phenytoin; Primidone; Protein Binding; Thyroid Function Tests; Thyroid Hormones; Thyrotropin; Thyroxine; Thyroxine-Binding Proteins; Triiodothyronine; Valproic Acid	1978
[Antiepileptics used currently]. La Revue du praticien, 1979, Dec-21, Volume: 29, Issue:59 Topics: Anticonvulsants; Barbiturates; Carbamazepine; Clonazepam; Diazepam; Humans; Hydantoins; Primidone; Succinimides; Valproic Acid	1979
[Undesirable effects of antiepileptics]. La Revue du praticien, 1979, Dec-21, Volume: 29, Issue:59 Topics: Anticonvulsants; Barbiturates; Benzodiazepines; Carbamazepine; Ethosuximide; Humans; Hydantoins; Primidone; Valproic Acid	1979
Drug interactions during anticonvulsant therapy in childhood: diphenylhydantoin, primidone, phenobarbitone, clonazepam, nitrazepam, carbamazepin and dipropylacetate. Neuropadiatrie, 1977, Volume: 8, Issue:1 Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clonazepam; Drug Interactions; Drug Therapy, Combination; Epilepsy; Humans; Nitrazepam; Phenobarbital; Phenytoin; Primidone; Valproic Acid	1977
[Plasma levels of anticonvulsants. Experiences with routine plasma level determination of 6 different anticonvulsants]. Fortschritte der Medizin, 1978, Jan-05, Volume: 96, Issue:1 Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Drug Therapy, Combination; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid	1978
Thyroid function tests in patients on long-term treatment with various anticonvulsant drugs. Clinical endocrinology, 1978, Volume: 8, Issue:3 Topics: Adolescent; Adult; Carbamazepine; Female; Humans; Male; Middle Aged; Phenytoin; Primidone; Thyroid Function Tests; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine; Valproic Acid	1978
[Ultrastructural changes of murine cerebellum after anticonvulsant administration. I. Acute intoxication (author's transl)]. Igaku kenkyu. Acta medica, 1977, Volume: 47, Issue:7 Topics: Acute Disease; Animals; Anticonvulsants; Cerebellum; Mice; Phenytoin; Primidone; Valproic Acid	1977
Long-term use of the major anticonvulsant drugs. American family physician, 1978, Volume: 18, Issue:4 Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Drug Interactions; Epilepsy; Ethosuximide; Female; Humans; Phenobarbital; Phenytoin; Pregnancy; Primidone; Time Factors; Valproic Acid	1978
Consecutive gas chromatographic determination of phenytoin, phenobarbital, primidone, phenylethylmalondiamide, carbamazepine, trimethadione, dimethadione, ethosuximide, and valproate from the same serum specimen. Epilepsia, 1978, Volume: 19, Issue:5 Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Dimethadione; Ethosuximide; Phenobarbital; Phenylethylmalonamide; Phenytoin; Primidone; Trimethadione; Valproic Acid	1978
Drugs for epilepsy. The Medical letter on drugs and therapeutics, 1979, Mar-23, Volume: 21, Issue:6 Topics: Anticonvulsants; Carbamazepine; Clonazepam; Diazepam; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Status Epilepticus; Valproic Acid	1979
Recent advances in drug therapy for epilepsy. Canadian Medical Association journal, 1979, Apr-07, Volume: 120, Issue:7 Topics: Anticonvulsants; Carbamazepine; Clonazepam; Drug Interactions; Epilepsy; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid	1979
The use of antiepileptic drugs. Annals of internal medicine, 1979, Volume: 90, Issue:2 Topics: Anticonvulsants; Benzodiazepines; Carbamazepine; Drug Interactions; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid	1979
[The serum concentration of anticonvulsants -- pharmacokinetic findings and practical therapeutic applications (author's transl)]. Wiener klinische Wochenschrift, 1979, Sep-14, Volume: 91, Issue:17 Topics: Antacids; Anticonvulsants; Biological Availability; Carbamazepine; Chromatography, Gas; Clonazepam; Dosage Forms; Ethosuximide; Half-Life; Humans; Immunoenzyme Techniques; Intestinal Absorption; Phenobarbital; Phenytoin; Primidone; Seizures; Valproic Acid	1979
[Clinical study of serum level of dipropylacetic acid sodium (Depakene) by gaschromatography (author's transl)]. No to shinkei = Brain and nerve, 1977, Volume: 29, Issue:8 Topics: Adolescent; Adult; Child; Child, Preschool; Chromatography, Gas; Drug Therapy, Combination; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Female; Humans; Male; Middle Aged; Phenobarbital; Primidone; Valerates; Valproic Acid	1977
[Measurement of the blood concentration of antiepileptic drugs. II Special cases]. La Nouvelle presse medicale, 1975, May-24, Volume: 4, Issue:21 Topics: Adult; Anticonvulsants; Carbamazepine; Child; Clonazepam; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid	1975
Letter: Sodium valproate in the treatment of intractable childhood epilepsy. Developmental medicine and child neurology, 1975, Volume: 17, Issue:4 Topics: Diazepam; Drug Therapy, Combination; Epilepsy; Phenobarbital; Phenytoin; Primidone; Pyridoxine; Valerates; Valproic Acid	1975
Elevation of diphenylhydantoin and primidone serum concentration by addition of dipropylacetate, a new anticonvulsant drug. Acta paediatrica Scandinavica, 1975, Volume: 64, Issue:5 Topics: Child; Drug Interactions; Drug Therapy, Combination; Epilepsy; Humans; Phenytoin; Primidone; Valerates; Valproic Acid	1975
The therapy of benign myoclonic epilepsy in infants. Epilepsy research. Supplement, 1992, Volume: 6 Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Drug Therapy, Combination; Electroencephalography; Epilepsies, Myoclonic; Ethosuximide; Female; Humans; Infant; Male; Primidone; Valproic Acid	1992
Antiepileptics and the development of congenital anomalies. Neurology, 1992, Volume: 42, Issue:4 Suppl 5 Topics: Abnormalities, Drug-Induced; Anticonvulsants; Apgar Score; Birth Weight; Carbamazepine; Epilepsy; Female; Fetus; Gestational Age; Head; Humans; Hydantoins; Infant; Infant, Newborn; Phenobarbital; Pregnancy; Pregnancy Complications; Primidone; Syndrome; Valproic Acid	1992
Performance of fluorescence polarisation immunoassay reagents for carbamazepine, phenytoin, phenobarbitone, primidone, and valproic acid on a Cobas Fara II analyser. Therapeutic drug monitoring, 1991, Volume: 13, Issue:6 Topics: Anticonvulsants; Carbamazepine; Evaluation Studies as Topic; Fluorescence Polarization Immunoassay; Humans; Phenobarbital; Phenytoin; Primidone; Reference Standards; Valproic Acid	1991
Anticonvulsant therapy increases fentanyl requirements during anaesthesia for craniotomy. Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1990, Volume: 37, Issue:3 Topics: Adolescent; Adult; Anesthesia, Intravenous; Anticonvulsants; Carbamazepine; Craniotomy; Drug Interactions; Epilepsy; Fentanyl; Humans; Middle Aged; Phenytoin; Primidone; Valproic Acid	1990
Simultaneous determination of six antiepileptic drugs by capillary gas chromatography. Journal of chromatography, 1990, May-18, Volume: 527, Issue:2 Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Ethosuximide; Humans; Hydroxides; Phenobarbital; Phenytoin; Potassium; Potassium Compounds; Primidone; Valproic Acid	1990
Development of monoclonal antibodies for therapeutic drug monitoring. Behring Institute Mitteilungen, 1990, Issue:86 Topics: Antibodies, Monoclonal; Anticonvulsants; Carbamazepine; Cross Reactions; Humans; Monitoring, Physiologic; Phenobarbital; Phenytoin; Primidone; Valproic Acid	1990
The treatment of severe action myoclonus. Brain : a journal of neurology, 1989, Volume: 112 ( Pt 3) Topics: Adolescent; Adult; Aged; Clonazepam; Drug Evaluation; Drug Therapy, Combination; Electromyography; Evoked Potentials, Somatosensory; Female; Follow-Up Studies; Humans; Male; Middle Aged; Myoclonus; Piracetam; Primidone; Valproic Acid	1989
The effect of concurrent administration of sodium valproate on serum levels of primidone and its metabolite phenobarbital. Journal of clinical pharmacy and therapeutics, 1989, Volume: 14, Issue:5 Topics: Adolescent; Adult; Child; Child, Preschool; Drug Interactions; Drug Therapy, Combination; Epilepsy; Humans; Middle Aged; Phenobarbital; Primidone; Retrospective Studies; Valproic Acid	1989
[Factors influencing the effectiveness of preventive treatment of febrile convulsions]. Anales espanoles de pediatria, 1989, Volume: 31, Issue:2 Topics: Anticonvulsants; Child; Drug Evaluation; Epilepsy; Female; Fever; Humans; Male; Phenobarbital; Primidone; Recurrence; Seizures; Spain; Valproic Acid	1989
Nursing interventions for anticonvulsant drug interactions. The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses, 1986, Volume: 18, Issue:5 Topics: Anticonvulsants; Biotransformation; Carbamazepine; Drug Interactions; Humans; Nursing Care; Patient Education as Topic; Phenobarbital; Phenytoin; Primidone; Valproic Acid	1986
Phenylethylmalonamide serum levels in patients treated with primidone and the effects of other antiepileptic drugs. Therapeutic drug monitoring, 1986, Volume: 8, Issue:2 Topics: Anticonvulsants; Carbamazepine; Drug Therapy, Combination; Epilepsy; Humans; Malonates; Phenobarbital; Phenylethylmalonamide; Phenytoin; Primidone; Valproic Acid	1986
Pharmacologic interactions between valproate and other drugs. The American journal of medicine, 1988, Jan-25, Volume: 84, Issue:1A Topics: Anticonvulsants; Carbamazepine; Drug Interactions; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid	1988
[Prognosis of complicated febrile convulsions in therapy with primidone, cathine-phenobarbital and calcium valproinate]. Kinderarztliche Praxis, 1988, Volume: 56, Issue:10 Topics: Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Infant; Male; Phenobarbital; Phenylpropanolamine; Primidone; Prognosis; Seizures, Febrile; Valproic Acid	1988
Effects of pregnancy on antiepileptic drug utilization. Epilepsia, 1985, Volume: 26 Suppl 1 Topics: Anticonvulsants; Biological Availability; Carbamazepine; Epilepsy; Female; Humans; Kinetics; Metabolic Clearance Rate; Patient Compliance; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Primidone; Valproic Acid	1985
Concurrent determination of valproic acid with other antiepileptic drugs by high-performance liquid chromatography. Journal of chromatography, 1985, Feb-27, Volume: 338, Issue:1 Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid	1985
Monotherapy and polytherapy for intractable epilepsies. Italian journal of neurological sciences, 1985, Volume: 6, Issue:2 Topics: Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Carbamazepine; Clobazam; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Phenobarbital; Phenytoin; Primidone; Valproic Acid	1985
Psychiatric implications of anticonvulsant drugs. The Journal of clinical psychiatry, 1980, Volume: 41, Issue:9 Topics: Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Carbamazepine; Dose-Response Relationship, Drug; Epilepsy; Humans; Mental Disorders; Phenobarbital; Phenytoin; Primidone; Valproic Acid	1980
Choice of anticonvulsants in epilepsy. Indian pediatrics, 1981, Volume: 18, Issue:5 Topics: Adult; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Carbamazepine; Child; Child, Preschool; Epilepsy; Ethosuximide; Follow-Up Studies; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid	1981
Mechanisms of action of antiepileptic drugs. Clinical neuropharmacology, 1982, Volume: 5, Issue:1 Topics: Acetazolamide; Animals; Anti-Anxiety Agents; Anticonvulsants; Barbiturates; Benzodiazepines; Carbamazepine; Chemical Phenomena; Chemistry; Humans; Paraldehyde; Phenytoin; Primidone; Seizures; Succinimides; Trimethadione; Valproic Acid	1982
The influence of antiepileptic drugs on the electroencephalogram: a review of controlled clinical studies. Electroencephalography and clinical neurophysiology. Supplement, 1982, Volume: 36 Topics: Anti-Anxiety Agents; Anticonvulsants; Brain; Carbamazepine; Clonazepam; Electroencephalography; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid	1982
[Rise in gamma-GT during anticonvulsive therapy]. Wiener klinische Wochenschrift, 1982, Nov-12, Volume: 94, Issue:21 Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Female; gamma-Glutamyltransferase; Humans; Liver; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone; Valproic Acid	1982
Pharmacokinetics of antiepileptic drugs. Acta neurologica Scandinavica. Supplementum, 1983, Volume: 97 Topics: Adult; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Carbamazepine; Child; Child, Preschool; Drug Interactions; Epilepsy; Ethosuximide; Female; Half-Life; Humans; Infant; Infant, Newborn; Intestinal Absorption; Kinetics; Male; Metabolic Clearance Rate; Phenobarbital; Phenytoin; Pregnancy; Primidone; Protein Binding; Valproic Acid	1983
Pharmacodynamic factors in the occurrence of psychiatric symptoms among patients with epilepsy. Folia psychiatrica et neurologica japonica, 1983, Volume: 37, Issue:3 Topics: Anticonvulsants; Barbiturates; Carbamazepine; Epilepsy; Folic Acid; Humans; Kinetics; Mental Disorders; Phenobarbital; Phenytoin; Primidone; Valproic Acid; Vitamin B 12	1983
Therapeutic aspects of kinesiogenic paroxysmal choreoathetosis and familial paroxysmal choreoathetosis of the Mount and Reback type. Journal of neurology, 1983, Volume: 230, Issue:3 Topics: Adolescent; Adult; Aged; Alcohol Drinking; Athetosis; Carbamazepine; Child; Chorea; Female; Haloperidol; Humans; Male; Middle Aged; Motor Activity; Pedigree; Phenytoin; Primidone; Valproic Acid	1983
Plasma arginine vasopressin concentrations in epileptics under monotherapy. Journal of neurology, 1983, Volume: 230, Issue:3 Topics: Adult; Anticonvulsants; Arginine Vasopressin; Carbamazepine; Epilepsy; Humans; Phenytoin; Primidone; Valproic Acid	1983
[Treatment of rapid nodding "salaam" spasms in childhood]. Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1980, Volume: 80, Issue:10 Topics: Adrenocorticotropic Hormone; Child, Preschool; Clonazepam; Electroencephalography; Female; Humans; Infant; Infant, Newborn; Male; Nitrazepam; Phenytoin; Primidone; Psychomotor Disorders; Spasms, Infantile; Valproic Acid	1980
Therapeutic monitoring of serum antiepileptic drug levels. Progress in clinical and biological research, 1983, Volume: 124 Topics: Anticonvulsants; Carbamazepine; Clonazepam; Ethosuximide; Humans; Laboratories; Monitoring, Physiologic; Phenobarbital; Phenytoin; Primidone; Time Factors; Valproic Acid	1983
Antiepileptic drugs and teratogenesis. How should patients, doctors and health authorities be counselled? Acta neurologica Scandinavica. Supplementum, 1983, Volume: 94 Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Infant, Newborn; Oxazoles; Phenytoin; Pregnancy; Pregnancy Complications; Primidone; Risk; Trimethadione; Valproic Acid	1983
Active metabolites in antiepileptic therapy. Reflections on a pharmacological joker. Acta neurologica Scandinavica. Supplementum, 1983, Volume: 94 Topics: Anticonvulsants; Biotransformation; Carbamazepine; Diazepam; Epilepsy; Humans; Kinetics; Primidone; Valproic Acid	1983
Treatment of the nonconvulsive epilepsies. Epilepsia, 1983, Volume: 24 Suppl 1 Topics: Anticonvulsants; Carbamazepine; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid	1983
[Pharmacotherapy of epilepsy--current problems and controversies]. Fortschritte der Neurologie-Psychiatrie, 1983, Volume: 51, Issue:11 Topics: Adolescent; Adult; Carbamazepine; Child; Child, Preschool; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epilepsy, Post-Traumatic; Epilepsy, Tonic-Clonic; Ethosuximide; Female; Humans; Infant; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Primidone; Seizures, Febrile; Status Epilepticus; Valproic Acid	1983
Effectiveness and toxicity of phenobarbital, primidone, and sodium valproate in the prevention of febrile convulsions, controlled by plasma levels. Epilepsia, 1984, Volume: 25, Issue:1 Topics: Child; Child, Preschool; Dose-Response Relationship, Drug; Female; Humans; Male; Phenobarbital; Primidone; Seizures, Febrile; Valproic Acid	1984
Unnecessary polypharmacy in patients with frequent seizures. Acta neurologica Scandinavica, 1984, Volume: 69, Issue:1 Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Clonazepam; Drug Therapy, Combination; Epilepsy; Ethosuximide; Female; Humans; Male; Phenobarbital; Phenytoin; Primidone; Valproic Acid	1984
The place of saliva in antiepileptic drug monitoring. Therapeutic drug monitoring, 1984, Volume: 6, Issue:1 Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Child; Female; Humans; Middle Aged; Phenobarbital; Plasma; Primidone; Saliva; Valproic Acid	1984
Enzyme induction in neonates after fetal exposure to antiepileptic drugs. Pediatric pharmacology (New York, N.Y.), 1983, Volume: 3, Issue:3-4 Topics: Aminopyrine; Aminopyrine N-Demethylase; Anticonvulsants; Breath Tests; Carbamazepine; Carbon Radioisotopes; Enzyme Induction; Female; Humans; Infant, Newborn; Liver; Male; Maternal-Fetal Exchange; Phenobarbital; Phenytoin; Pregnancy; Primidone; Valproic Acid	1983
A comparative study of the relative enzyme inducing properties of anticonvulsant drugs in epileptic patients. British journal of clinical pharmacology, 1984, Volume: 18, Issue:3 Topics: Anticonvulsants; Antipyrine; Carbamazepine; Enzyme Induction; Epilepsy; Female; Glucaric Acid; Half-Life; Humans; Immunoenzyme Techniques; Male; Microsomes, Liver; Phenobarbital; Phenytoin; Primidone; Valproic Acid	1984
Pharmacologic therapy of seizures in the elderly. Hospital practice (Office ed.), 1984, Volume: 19, Issue:11 Topics: Aged; Anticonvulsants; Carbamazepine; Humans; Phenobarbital; Phenytoin; Primidone; Seizures; Status Epilepticus; Valproic Acid	1984
[Plasma levels of antiepileptic agents in the treatment of epilepsy]. Arquivos de neuro-psiquiatria, 1984, Volume: 42, Issue:3 Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clonazepam; Drug Interactions; Drug Therapy, Combination; Epilepsy; Ethosuximide; Female; Humans; Infant; Infant, Newborn; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone; Valproic Acid	1984
One drug for childhood grand mal: medical audit for three-year remissions. Developmental medicine and child neurology, 1984, Volume: 26, Issue:6 Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clonazepam; Epilepsy, Tonic-Clonic; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid	1984
[Anticonvulsive combined therapy (author's transl)]. Wiener klinische Wochenschrift, 1980, Jan-04, Volume: 92, Issue:1 Topics: Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsy; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid	1980
[Autoallergic drug exanthemas]. Fortschritte der Medizin, 1980, May-22, Volume: 98, Issue:19 Topics: Autoimmune Diseases; Child; Epilepsy; Female; Humans; Lupus Erythematosus, Systemic; Male; Pemphigus; Primidone; Valproic Acid	1980
Therapeutic alternatives in phenytoin-induced gingival hyperplasia. A case report and discussion. Journal of periodontology, 1980, Volume: 51, Issue:9 Topics: Adolescent; Epilepsy; Female; Gingival Hyperplasia; Humans; Phenytoin; Primidone; Valproic Acid	1980
[Anticonvulsants and their side effects. I. Basis and principles of anticonvulsant therapy]. Kinderarztliche Praxis, 1980, Volume: 48, Issue:8 Topics: Anticonvulsants; Barbiturates; Benzodiazepines; Carbamazepine; Humans; Hydantoins; Primidone; Succinimides; Valproic Acid	1980
Hepatotoxicity of sodium valproate and other anticonvulsants in rat hepatocyte cultures. Epilepsia, 1980, Volume: 21, Issue:6 Topics: Animals; Anticonvulsants; Clonazepam; Culture Techniques; Dose-Response Relationship, Drug; L-Lactate Dehydrogenase; Liver; Phenobarbital; Phenytoin; Primidone; Rats; Valproic Acid	1980
[Problems of therapeutic service in primidone therapy]. Zeitschrift fur arztliche Fortbildung, 1980, Aug-01, Volume: 74, Issue:15 Topics: Adolescent; Drug Administration Schedule; Drug Interactions; Epilepsy, Tonic-Clonic; Female; Half-Life; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid	1980
Valproic acid and plasma levels of primidone and derived phenobarbital. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 1981, Volume: 8, Issue:1 Topics: Adult; Drug Interactions; Drug Therapy, Combination; Epilepsy, Temporal Lobe; Female; Humans; Kinetics; Male; Phenobarbital; Primidone; Valproic Acid	1981
Drug treatment of epilepsy. Comprehensive therapy, 1981, Volume: 7, Issue:4 Topics: Anticonvulsants; Carbamazepine; Clonazepam; Electroencephalography; Epilepsy; Ethosuximide; Female; Humans; Phenobarbital; Phenytoin; Pregnancy; Primidone; Seizures; Substance Withdrawal Syndrome; Valproic Acid	1981
Phenobarbital, primidone and sodium valproate in the prophylaxis of febrile convulsions. Brain & development, 1981, Volume: 3, Issue:4 Topics: Child, Preschool; Dose-Response Relationship, Drug; Humans; Infant; Phenobarbital; Primidone; Recurrence; Seizures, Febrile; Valproic Acid	1981
Daily fluctuations of dipropylacetate (DPA) serum level in epileptic patients. Monographs in neural sciences, 1980, Volume: 5 Topics: Adolescent; Adult; Carbamazepine; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Phenytoin; Primidone; Time Factors; Valproic Acid	1980
Drugs in the treatment of tinnitus. Ciba Foundation symposium, 1981, Volume: 85 Topics: Amobarbital; Antidepressive Agents, Tricyclic; Carbamazepine; Ethanol; Humans; Lidocaine; Phenytoin; Primidone; Tinnitus; Valproic Acid	1981
EEG quantification of drug level effects in monkey model of partial epilepsy. Electroencephalography and clinical neurophysiology. Supplement, 1982, Volume: 36 Topics: Animals; Anticonvulsants; Circadian Rhythm; Clonazepam; Disease Models, Animal; Electroencephalography; Kinetics; Macaca mulatta; Male; Phenobarbital; Phenytoin; Primidone; Seizures; Valproic Acid	1982
Two antiepileptic drugs for intractable epilepsy with complex-partial seizures. Journal of neurology, neurosurgery, and psychiatry, 1982, Volume: 45, Issue:12 Topics: Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsy, Temporal Lobe; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid	1982
[A study on cerebrospinal fluid and saliva to serum concentration ratios of anticonvulsants--Phenytoin, Phenobarbital, Valproic Acid and Primidone in epileptic patients]. Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica, 1982, Volume: 84, Issue:9 Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Epilepsy; Humans; Middle Aged; Phenobarbital; Phenytoin; Primidone; Saliva; Valproic Acid	1982
Practical considerations in anticonvulsant therapy--Part 2. American pharmacy, 1995, Volume: NS35, Issue:9 Topics: Anticonvulsants; Benzodiazepines; Cost Control; Epilepsy; Ethosuximide; Humans; Monitoring, Physiologic; Patient Compliance; Patient Education as Topic; Pharmacists; Phenobarbital; Phenytoin; Primidone; Role; Valproic Acid	1995
Epilepsy treatment in The Netherlands. Comparison of matched groups of two medical centres. Acta neurologica Scandinavica, 1994, Volume: 89, Issue:6 Topics: Adolescent; Adult; Carbamazepine; Diazepam; Epilepsy; Ethosuximide; Female; gamma-Aminobutyric Acid; Humans; Male; Netherlands; Phenobarbital; Phenytoin; Primidone; Quality of Health Care; Statistics, Nonparametric; Treatment Outcome; Valproic Acid; Vigabatrin	1994
Nonconvulsive status epilepticus. The American journal of emergency medicine, 1997, Volume: 15, Issue:7 Topics: Anticonvulsants; Dizziness; Electroencephalography; Emergency Service, Hospital; Epilepsy, Tonic-Clonic; Humans; Lorazepam; Male; Middle Aged; Neurologic Examination; Phenobarbital; Primidone; Status Epilepticus; Valproic Acid	1997
Accelerated recovery and disposition from rocuronium in an end-stage renal failure patient on chronic anticonvulsant therapy with sodium valproate and primidone. British journal of anaesthesia, 1998, Volume: 80, Issue:3 Topics: Adult; Androstanols; Anticonvulsants; Drug Interactions; Humans; Kidney Failure, Chronic; Male; Neuromuscular Junction; Neuromuscular Nondepolarizing Agents; Primidone; Rocuronium; Valproic Acid	1998
Homocysteine concentrations and methionine loading in patients on antiepileptic drugs. Acta neurologica Scandinavica, 2000, Volume: 101, Issue:4 Topics: Adult; Aged; Anticonvulsants; Carbamazepine; Case-Control Studies; Cytochrome P-450 Enzyme System; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Middle Aged; Phenobarbital; Phenytoin; Primidone; Treatment Outcome; Valproic Acid; Vitamin B 12	2000
Levetiracetam in focal epilepsy and hepatic porphyria: a case report. Epilepsia, 2004, Volume: 45, Issue:5 Topics: Acute Disease; Adult; Anticonvulsants; Comorbidity; Epilepsies, Partial; Female; Humans; Levetiracetam; Piracetam; Porphyrias, Hepatic; Primidone; Valproic Acid	2004
Robust isocratic high performance liquid chromatographic method for simultaneous determination of seven antiepileptic drugs including lamotrigine, oxcarbazepine and zonisamide in serum after solid-phase extraction. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2007, Sep-15, Volume: 857, Issue:1 Topics: Analysis of Variance; Animals; Anticonvulsants; Carbamazepine; Cattle; Chromatography, High Pressure Liquid; Drug Monitoring; Ethosuximide; Humans; Isoxazoles; Lamotrigine; Oxcarbazepine; Phenobarbital; Phenytoin; Primidone; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Solid Phase Extraction; Solutions; Specimen Handling; Spectrophotometry, Ultraviolet; Temperature; Triazines; Valproic Acid; Zonisamide	2007
Drug-induced pertubation of the aminothiol redox-status in patients with epilepsy: improvement by B-vitamins. Epilepsy research, 2008, Volume: 82, Issue:1 Topics: Adult; Anticonvulsants; Carbamazepine; Case-Control Studies; Cysteine; Dipeptides; Drug Evaluation; Epilepsy; Female; Folic Acid; Humans; Hyperhomocysteinemia; Liver; Male; Methionine; Oxidation-Reduction; Phenobarbital; Phenytoin; Primidone; Pyridoxine; Riboflavin; Valproic Acid; Vitamin B Deficiency	2008
Antiepleptic drug interactions: a clinical case demonstration. Casopis lekaru ceskych, 2011, Volume: 150, Issue:8 Topics: Adolescent; Anticonvulsants; Brain; Carbamazepine; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Phenobarbital; Primidone; Valproic Acid	2011
How did phenobarbital's chemical structure affect the development of subsequent antiepileptic drugs (AEDs)? Epilepsia, 2012, Volume: 53 Suppl 8 Topics: Anticonvulsants; Carbamazepine; Drug Discovery; Epilepsy; Ethosuximide; History, 20th Century; Humans; Mephenytoin; Mephobarbital; Phenobarbital; Phenytoin; Primidone; Structure-Activity Relationship; Succinimides; Valproic Acid	2012
Antiepileptic drugs: Impacts on human serum paraoxonase-1. Journal of biochemical and molecular toxicology, 2017, Volume: 31, Issue:6 Topics: Amines; Anticonvulsants; Aryldialkylphosphatase; Cyclohexanecarboxylic Acids; Enzyme Inhibitors; Gabapentin; gamma-Aminobutyric Acid; Humans; Kinetics; Levetiracetam; Phenytoin; Piracetam; Primidone; Turkey; Valproic Acid	2017
Beneficial effects of primidone in Niemann-Pick disease type C (NPC)-model cells and mice: Reduction of unesterified cholesterol levels in cells and extension of lifespan in mice. European journal of pharmacology, 2021, Apr-05, Volume: 896 Topics: Animals; Biological Transport; CHO Cells; Cholesterol; Cricetulus; Disease Models, Animal; Endoplasmic Reticulum; Endosomes; Fibroblasts; Humans; Intracellular Signaling Peptides and Proteins; Longevity; Lysosomes; Mice, Inbred BALB C; Mice, Knockout; Motor Activity; Niemann-Pick C1 Protein; Niemann-Pick Disease, Type C; Primidone; Time Factors; Valproic Acid	2021