valproic acid and pirenzepine

valproic acid has been researched along with pirenzepine in 40 studies

Research

Studies (40)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (5.00)	18.2507
2000's	36 (90.00)	29.6817
2010's	2 (5.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Filipek, B; Gunia-Krzyżak, A; Marona, H; Nitek, W; Pańczyk, K; Pękala, E; Rapacz, A; Słoczyńska, K; Waszkielewicz, AM; Żelaszczyk, D; Żesławska, E	1
DeGolia, SG; Dunai, M; Ketter, TA; Strong, CM; Tate, DL; Winsberg, ME	1
Grundy, S; Tohen, M	1
Chang, KD; Ketter, TA	1
Finkel, J; Hird, S; Solhkhah, R	1
DeVaney, GT; Grove, VE; Quintanilla, J	1
Ghaemi, SN; Guille, C; Sachs, GS	1
Nemeroff, CB	1
Ghaemi, SN	1
Gundlapalli, SP; Iqbal, MM; Passman, TE; Ryals, T; Ryan, WG	1
Grace, JJ; Narendran, R; Pato, MT; Pristach, CA; Valenti, AM; Young, CM	1
Baker, RW; Bowden, CL; Breier, A; Calabrese, JR; Chengappa, KN; Feldman, PD; Keeter, EL; Kupfer, DJ; Risser, RC; Sachs, GS; Suppes, T; Tohen, M; Tollefson, GD; Zarate, CA	1
Meyer, JM	1
Altshuler, LL; Baker, RW; Breier, A; Gilmore, JA; Ketter, TA; Milton, DR; Risser, R; Suppes, T; Tohen, M; Tollefson, GA; Zarate, CA	1
Abulseoud, O; Castelo, C; Kingsbury, SJ	1
Fernandez-Corres, B; Gonzalez-Pinto, A; Gutierrez, M; Lalaguna, B; Micó, JA; Pérez-Heredia, JL; Tohen, M	1
Ingram, W; Mann, JR; Olson, DA	1
Casey, DE; Daniel, DG; Sommerville, KW; Tracy, KA; Wassef, AA; Wozniak, P	1
Good, CR; Krecko, VF; Petersen, CA	1
Sachs, G; Sommerville, KW; Swann, AC; Weisler, R; Wozniak, P; Zajecka, JM	1
Altshuler, LL; Frye, MA; Gitlin, MJ	1
Shelton, RC	1
Keck, PE	1
Maguire, GA; Phillips, G	1
Paramore, LC; Revicki, DA; Sommerville, KW; Swann, AC; Zajecka, JM	1
Chen, PS; Lo, YC; Wang, YT; Yang, YK; Yeh, TL	1
Freeman, MP; Gelenberg, AJ; Gnanadesikan, M	1
Altshuler, L; Baker, RW; Brown, E; Frye, M; Ketter, TA; Risser, RC; Schuh, LM; Suppes, T; Tohen, M; Zajecka, J; Zarate, CA	1
Iwazaki, H	1
Basile, VS; Kennedy, SH; Mancini, DA; McIntyre, RS; Srinivasan, J	1
Baker, JD; Hirschfeld, RM; Sommerville, KW; Tracy, K; Wozniak, P	1
Arguisola, MS; Tavakoli, SA	1
Isaac, MB; Isaac, MT	1
Gonzalez-Heydrich, J; Leichtner, A; Mezzacappa, E; Raches, D; Wilens, TE	1
Dittmann, S; Grunze, H	1
Vieta, E	1

Reviews

12 review(s) available for valproic acid and pirenzepine

Article	Year
Management of acute mania. The Journal of clinical psychiatry, 1999, Volume: 60 Suppl 5 Topics: Acute Disease; Algorithms; Anticonvulsants; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Carbamazepine; Clinical Trials as Topic; Humans; Lithium; Olanzapine; Pirenzepine; Research Design; Risk Factors; Treatment Outcome; Treatment Refusal; Valproic Acid	1999
An ever-increasing pharmacopoeia for the management of patients with bipolar disorder. The Journal of clinical psychiatry, 2000, Volume: 61 Supp 13 Topics: Acetates; Amines; Anticonvulsants; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Carbamazepine; Clozapine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Electroconvulsive Therapy; Electromagnetic Phenomena; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Lithium; Olanzapine; Pirenzepine; Risperidone; Topiramate; Treatment Outcome; Triazines; Valproic Acid	2000
New treatments for bipolar disorder: the role of atypical neuroleptic agents. The Journal of clinical psychiatry, 2000, Volume: 61 Suppl 14 Topics: Acute Disease; Algorithms; Anticonvulsants; Antidepressive Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Clozapine; Dibenzothiazepines; Drug Therapy, Combination; Humans; Lithium; Olanzapine; Pirenzepine; Psychotic Disorders; Quetiapine Fumarate; Risperidone; Treatment Outcome; Valproic Acid	2000
Effects of antimanic mood-stabilizing drugs on fetuses, neonates, and nursing infants. Southern medical journal, 2001, Volume: 94, Issue:3 Topics: Abnormalities, Drug-Induced; Acetates; Adult; Amines; Antimanic Agents; Benzodiazepines; Breast Feeding; Carbamazepine; Cyclohexanecarboxylic Acids; Female; Fetus; Gabapentin; gamma-Aminobutyric Acid; Haloperidol; Humans; Infant, Newborn; Lithium; Mood Disorders; Olanzapine; Pirenzepine; Placenta; Pregnancy; Risk Factors; Valproic Acid	2001
Treating acute mania. The Journal of family practice, 2003, Volume: Suppl Topics: Acute Disease; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Humans; Lithium Compounds; Olanzapine; Pirenzepine; Valproic Acid	2003
Treating bipolar depression. The Journal of family practice, 2003, Volume: Suppl Topics: Acetates; Affect; Amines; Anticonvulsants; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Carbamazepine; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Lithium Compounds; Nipecotic Acids; Olanzapine; Oxcarbazepine; Pirenzepine; Tiagabine; Topiramate; Treatment Outcome; Triazines; Valproic Acid; Zonisamide	2003
Long-term therapy of bipolar illness. The Journal of family practice, 2003, Volume: Suppl Topics: Affect; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Carbamazepine; Controlled Clinical Trials as Topic; Humans; Lamotrigine; Lithium Compounds; Olanzapine; Pirenzepine; Secondary Prevention; Time Factors; Treatment Outcome; Triazines; Valproic Acid	2003
Optimal dosing of medications (in bipolar disorder). The Journal of family practice, 2003, Volume: Suppl Topics: Acute Disease; Affect; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Chronic Disease; Drug Administration Schedule; Humans; Lithium Compounds; Olanzapine; Pirenzepine; Treatment Outcome; Valproic Acid	2003
Alternatives to lithium and divalproex in the maintenance treatment of bipolar disorder. Bipolar disorders, 2003, Volume: 5, Issue:3 Topics: Acetates; Amines; Anticonvulsants; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Calcium Channel Blockers; Carbamazepine; Clozapine; Cyclohexanecarboxylic Acids; Dibenzothiazepines; Donepezil; Fatty Acids, Omega-3; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Indans; Lamotrigine; Lithium Carbonate; Olanzapine; Piperazines; Piperidines; Pirenzepine; Quetiapine Fumarate; Risperidone; Thiazoles; Topiramate; Treatment Outcome; Triazines; Valproic Acid	2003
[Manic phase (manic episode)]. Ryoikibetsu shokogun shirizu, 2003, Issue:38 Topics: Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Diagnostic and Statistical Manual of Mental Disorders; Electroconvulsive Therapy; Humans; Lithium; Olanzapine; Pirenzepine; Psychotherapy; Reference Standards; Valproic Acid	2003
The safety and early efficacy of oral-loaded divalproex versus standard-titration divalproex, lithium, olanzapine, and placebo in the treatment of acute mania associated with bipolar disorder. The Journal of clinical psychiatry, 2003, Volume: 64, Issue:7 Topics: Acute Disease; Adolescent; Adult; Aged; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Diagnostic and Statistical Manual of Mental Disorders; Double-Blind Method; Drug Tolerance; Female; Humans; Lithium; Male; Middle Aged; Olanzapine; Pirenzepine; Randomized Controlled Trials as Topic; Severity of Illness Index; Titrimetry; Treatment Outcome; Valproic Acid	2003
[Treatment of acute bipolar disorder. Intriguing balancing act between mania and depression]. MMW Fortschritte der Medizin, 2003, May-26, Volume: 145 Suppl 2 Topics: Acute Disease; Algorithms; Antidepressive Agents; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Carbamazepine; Drug Therapy, Combination; Humans; Isotopes; Lamotrigine; Lithium; Olanzapine; Pirenzepine; Risperidone; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Triazines; Valproic Acid	2003

Trials

11 trial(s) available for valproic acid and pirenzepine

Article	Year
A naturalistic comparison of clozapine, risperidone, and olanzapine in the treatment of bipolar disorder. The Journal of clinical psychiatry, 2000, Volume: 61, Issue:9 Topics: Adult; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Bipolar Disorder; Body Weight; Clozapine; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Lithium; Male; Olanzapine; Pirenzepine; Psychiatric Status Rating Scales; Retrospective Studies; Risperidone; Treatment Outcome; Valproic Acid	2000
Olanzapine therapy in treatment-resistant psychotic mood disorders: a long-term follow-up study. The Journal of clinical psychiatry, 2001, Volume: 62, Issue:7 Topics: Adult; Affective Disorders, Psychotic; Aged; Anticonvulsants; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Brief Psychiatric Rating Scale; Cohort Studies; Depressive Disorder; Drug Therapy, Combination; Female; Follow-Up Studies; Hospitalization; Humans; Lithium; Male; Middle Aged; Olanzapine; Pirenzepine; Psychiatric Status Rating Scales; Psychotic Disorders; Schizophrenia; Treatment Outcome; Valproic Acid	2001
Efficacy of olanzapine in combination with valproate or lithium in the treatment of mania in patients partially nonresponsive to valproate or lithium monotherapy. Archives of general psychiatry, 2002, Volume: 59, Issue:1 Topics: Acute Disease; Adult; Antimanic Agents; Benzodiazepines; Bipolar Disorder; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Lithium Carbonate; Male; Middle Aged; Olanzapine; Pirenzepine; Psychiatric Status Rating Scales; Treatment Outcome; Valproic Acid	2002
Olanzapine versus divalproex in the treatment of acute mania. The American journal of psychiatry, 2002, Volume: 159, Issue:6 Topics: Acute Disease; Adult; Anticonvulsants; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Double-Blind Method; Female; Humans; Male; Olanzapine; Pirenzepine; Treatment Outcome; Valproic Acid	2002
Treatment of bipolar I rapid cycling patients during dysphoric mania with olanzapine. Journal of clinical psychopharmacology, 2002, Volume: 22, Issue:5 Topics: Adult; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Carbamazepine; Chemotherapy, Adjuvant; Female; Humans; Lithium; Male; Middle Aged; Olanzapine; Pirenzepine; Psychiatric Status Rating Scales; Time Factors; Valproic Acid	2002
Effect of divalproex combined with olanzapine or risperidone in patients with an acute exacerbation of schizophrenia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2003, Volume: 28, Issue:1 Topics: Adolescent; Adult; Aged; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Olanzapine; Pirenzepine; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Schizophrenic Psychology; Valproic Acid	2003
A comparison of the efficacy, safety, and tolerability of divalproex sodium and olanzapine in the treatment of bipolar disorder. The Journal of clinical psychiatry, 2002, Volume: 63, Issue:12 Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Double-Blind Method; Drug Therapy, Combination; Drug Tolerance; Female; Humans; Male; Middle Aged; Olanzapine; Pirenzepine; Valproic Acid	2002
Divalproex sodium versus olanzapine in the treatment of acute mania in bipolar disorder: health-related quality of life and medical cost outcomes. The Journal of clinical psychiatry, 2003, Volume: 64, Issue:3 Topics: Acute Disease; Adult; Ambulatory Care; Anticonvulsants; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Double-Blind Method; Drug Administration Schedule; Female; Follow-Up Studies; Health Care Costs; Health Services; Health Status; Humans; Male; Olanzapine; Pirenzepine; Psychiatric Status Rating Scales; Quality of Life; Treatment Outcome; Valproic Acid	2003
Olanzapine versus divalproex sodium for the treatment of acute mania and maintenance of remission: a 47-week study. The American journal of psychiatry, 2003, Volume: 160, Issue:7 Topics: Acute Disease; Adult; Anticonvulsants; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Double-Blind Method; Female; Follow-Up Studies; Humans; Male; Olanzapine; Pirenzepine; Psychiatric Status Rating Scales; Secondary Prevention; Survival Analysis; Treatment Outcome; Valproic Acid	2003
Antipsychotic-induced weight gain: bipolar disorder and leptin. Journal of clinical psychopharmacology, 2003, Volume: 23, Issue:4 Topics: Adolescent; Adult; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Body Mass Index; Female; Humans; Leptin; Lithium; Male; Middle Aged; Olanzapine; Pirenzepine; Risperidone; Valproic Acid; Weight Gain	2003
The safety and early efficacy of oral-loaded divalproex versus standard-titration divalproex, lithium, olanzapine, and placebo in the treatment of acute mania associated with bipolar disorder. The Journal of clinical psychiatry, 2003, Volume: 64, Issue:7 Topics: Acute Disease; Adolescent; Adult; Aged; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Diagnostic and Statistical Manual of Mental Disorders; Double-Blind Method; Drug Tolerance; Female; Humans; Lithium; Male; Middle Aged; Olanzapine; Pirenzepine; Randomized Controlled Trials as Topic; Severity of Illness Index; Titrimetry; Treatment Outcome; Valproic Acid	2003

Other Studies

18 other study(ies) available for valproic acid and pirenzepine

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
Structure-anticonvulsant activity studies in the group of (E)-N-cinnamoyl aminoalkanols derivatives monosubstituted in phenyl ring with 4-Cl, 4-CH Bioorganic & medicinal chemistry, 2017, 01-15, Volume: 25, Issue:2 Topics: Amino Alcohols; Animals; Anticonvulsants; Crystallography, X-Ray; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Mice; Models, Molecular; Molecular Structure; Rats; Seizures; Structure-Activity Relationship	2017
Rapid efficacy of olanzapine augmentation in nonpsychotic bipolar mixed states. The Journal of clinical psychiatry, 1998, Volume: 59, Issue:2 Topics: Adult; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Drug Therapy, Combination; Female; Humans; Lithium; Male; Middle Aged; Olanzapine; Pirenzepine; Thyroxine; Valproic Acid	1998
Mood stabilizer augmentation with olanzapine in acutely manic children. Journal of child and adolescent psychopharmacology, 2000,Spring, Volume: 10, Issue:1 Topics: Antimanic Agents; Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Benzodiazepines; Bipolar Disorder; Child; Drug Therapy, Combination; Humans; Lithium Chloride; Male; Olanzapine; Pirenzepine; Sleep Stages; Valproic Acid; Weight Gain	2000
Possible risperidone-induced visual hallucinations. Journal of the American Academy of Child and Adolescent Psychiatry, 2000, Volume: 39, Issue:9 Topics: Adolescent; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Diagnosis, Dual (Psychiatry); Drug Therapy, Combination; Female; Hallucinations; Humans; Olanzapine; Pirenzepine; Risperidone; Substance-Related Disorders; Treatment Outcome; Valproic Acid	2000
Improvement of Huntington's disease with olanzapine and valproate. The New England journal of medicine, 2000, Sep-28, Volume: 343, Issue:13 Topics: Adult; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Drug Therapy, Combination; Female; Humans; Huntington Disease; Male; Middle Aged; Olanzapine; Pirenzepine; Valproic Acid	2000
A retrospective comparison of weight, lipid, and glucose changes between risperidone- and olanzapine-treated inpatients: metabolic outcomes after 1 year. The Journal of clinical psychiatry, 2002, Volume: 63, Issue:5 Topics: Adult; Aged; Anticonvulsants; Antipsychotic Agents; Benzodiazepines; Blood Glucose; Body Weight; Diabetes Mellitus; Drug Therapy, Combination; Fasting; Female; Glucose Tolerance Test; Hospitalization; Humans; Hyperlipidemias; Lipid Metabolism; Lipids; Lithium; Male; Middle Aged; Olanzapine; Outcome Assessment, Health Care; Pirenzepine; Retrospective Studies; Risperidone; Schizophrenia; Valproic Acid	2002
Quetiapine for olanzapine-induced galactorrhea. The American journal of psychiatry, 2002, Volume: 159, Issue:6 Topics: Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Benzodiazepines; Dibenzothiazepines; Drug Therapy, Combination; Female; Galactorrhea; Humans; Olanzapine; Pirenzepine; Prolactin; Quetiapine Fumarate; Valproic Acid	2002
Combination of olanzapine and divalproex for agitation in individuals with profound mental retardation. Journal of clinical psychopharmacology, 2002, Volume: 22, Issue:5 Topics: Adult; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Drug Therapy, Combination; Female; Humans; Intellectual Disability; Male; Olanzapine; Pirenzepine; Psychomotor Agitation; Valproic Acid	2002
Valproic Acid and risperidone. Journal of the American Academy of Child and Adolescent Psychiatry, 2003, Volume: 42, Issue:1 Topics: Adolescent; Anticonvulsants; Antipsychotic Agents; Benzodiazepines; Child; Drug Interactions; Humans; Olanzapine; Pirenzepine; Retrospective Studies; Risperidone; Valproic Acid	2003
Nonketotic hyperosmolar syndrome from olanzapine, lithium, and valproic acid cotreatment. The Annals of pharmacotherapy, 2003, Volume: 37, Issue:6 Topics: Adult; Benzodiazepines; Drug Therapy, Combination; Humans; Hyperglycinemia, Nonketotic; Lithium Chloride; Male; Olanzapine; Pirenzepine; Valproic Acid	2003
Diabetic ketoacidosis in a patient treated with olanzapine, valproic acid, and venlafaxine. Southern medical journal, 2003, Volume: 96, Issue:7 Topics: Adult; Anticonvulsants; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Cyclohexanols; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetic Ketoacidosis; Drug Interactions; Drug Therapy, Combination; Humans; Male; Obesity; Olanzapine; Pirenzepine; Risk Factors; Valproic Acid; Venlafaxine Hydrochloride	2003
Effect of divalproex combined with olanzapine or risperidone in patients with an acute exacerbation of schizophrenia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2003, Volume: 28, Issue:11 Topics: Benzodiazepines; Brief Psychiatric Rating Scale; Drug Therapy, Combination; Humans; Male; Olanzapine; Pirenzepine; Risperidone; Schizophrenia; Valproic Acid	2003
Retrospective study of hepatic enzyme elevations in children treated with olanzapine, divalproex, and their combination. Journal of the American Academy of Child and Adolescent Psychiatry, 2003, Volume: 42, Issue:10 Topics: Adolescent; Alanine Transaminase; Antimanic Agents; Antipsychotic Agents; Aspartate Aminotransferases; Benzodiazepines; Child; Child, Preschool; Drug Interactions; Female; Humans; L-Lactate Dehydrogenase; Liver; Male; Olanzapine; Pancreatitis; Pirenzepine; Retrospective Studies; Valproic Acid	2003
[Fast control of manic or mixed episodes. Atypical neuroleptics for bipolar patients]. MMW Fortschritte der Medizin, 2003, May-26, Volume: 145 Suppl 2 Topics: Acute Disease; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Clinical Trials as Topic; Dopamine Antagonists; Drug Therapy, Combination; Haloperidol; Humans; Isotopes; Lithium; Olanzapine; Pirenzepine; Selective Serotonin Reuptake Inhibitors; Time Factors; Valproic Acid	2003
[Long-term therapy with intuition]. MMW Fortschritte der Medizin, 2003, May-26, Volume: 145 Suppl 2 Topics: Acute Disease; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Clinical Trials as Topic; Drug Therapy, Combination; Hospitalization; Humans; Isotopes; Lithium; Olanzapine; Patient Readmission; Pirenzepine; Placebos; Recurrence; Selective Serotonin Reuptake Inhibitors; Time Factors; Valproic Acid	2003
Divalproex versus olanzapine in mania. The Journal of clinical psychiatry, 2003, Volume: 64, Issue:10 Topics: Anticonvulsants; Antipsychotic Agents; Benzodiazepines; Bias; Bipolar Disorder; Clinical Trials as Topic; Humans; Olanzapine; Pirenzepine; Psychiatric Status Rating Scales; Treatment Outcome; Valproic Acid	2003