valproic acid and panobinostat

valproic acid has been researched along with panobinostat in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (9.09)29.6817
2010's8 (72.73)24.3611
2020's2 (18.18)2.80

Authors

AuthorsStudies
Corey, DR; Sakurai, F; Yu, D1
Forgione, M; Hailu, GS; Mai, A; Robaa, D; Rotili, D; Sippl, W1
Brindisi, M; Brogi, S; Butini, S; Campiani, G; Gemma, S; Saraswati, AP1
Alfano, AI; Barone, S; Brindisi, M; Cassese, E; Summa, V1
Blümcke, I; Coras, R; Garbes, L; Hahnen, E; Hauke, J; Heller, R; Hölker, I; Riessland, M; Tränkle, C; Wirth, B1
Biçaku, E; Marchion, DC; Münster, PN; Thomas, S; Thurn, KT1
Agapova, OA; Bowcock, AM; Harbour, JW; Kneass, ZT; Landreville, S; Lee, RS; Matatall, KA; Onken, MD1
Bug, G; Romanski, A1
Beyer, M; Kiweler, N; Krämer, OH; Mahboobi, S1
Figg, WD; Goey, AK; Peer, CJ; Sissung, TM1
Baude, A; Blagitko-Dorfs, N; Brocks, D; Greve, G; Lübbert, M; Meier, R; Pfeifer, D; Plass, C; Schlosser, P1

Reviews

3 review(s) available for valproic acid and panobinostat

ArticleYear
Lysine Deacetylase Inhibitors in Parasites: Past, Present, and Future Perspectives.
    Journal of medicinal chemistry, 2017, 06-22, Volume: 60, Issue:12

    Topics: Animals; Antiparasitic Agents; Drug Repositioning; Helminth Proteins; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Leishmania; Plasmodium; Protozoan Proteins; Schistosoma; Toxoplasma; Trypanosoma

2017
Chasing a Breath of Fresh Air in Cystic Fibrosis (CF): Therapeutic Potential of Selective HDAC6 Inhibitors to Tackle Multiple Pathways in CF Pathophysiology.
    Journal of medicinal chemistry, 2022, 02-24, Volume: 65, Issue:4

    Topics: Animals; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Histone Deacetylase 6; Humans; Signal Transduction

2022
Pharmacogenomics and histone deacetylase inhibitors.
    Pharmacogenomics, 2016, Volume: 17, Issue:16

    Topics: Depsipeptides; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Indoles; Panobinostat; Pharmacogenetics; Sulfonamides; Valproic Acid; Vorinostat

2016

Other Studies

8 other study(ies) available for valproic acid and panobinostat

ArticleYear
Clonal Rett Syndrome cell lines to test compounds for activation of wild-type MeCP2 expression.
    Bioorganic & medicinal chemistry letters, 2011, Sep-15, Volume: 21, Issue:18

    Topics: Clone Cells; Epigenesis, Genetic; Fibroblasts; Gene Expression Profiling; Humans; Methyl-CpG-Binding Protein 2; Molecular Structure; Mutation; Organic Chemicals; Polymerase Chain Reaction; Rett Syndrome; RNA, Messenger; Stereoisomerism

2011
Old but Gold: Tracking the New Guise of Histone Deacetylase 6 (HDAC6) Enzyme as a Biomarker and Therapeutic Target in Rare Diseases.
    Journal of medicinal chemistry, 2020, 01-09, Volume: 63, Issue:1

    Topics: Animals; Biomarkers; Cell Line; Epigenesis, Genetic; Histone Deacetylase 6; Histone Deacetylase Inhibitors; Humans; Mice; Protein Processing, Post-Translational; Rare Diseases

2020
LBH589 induces up to 10-fold SMN protein levels by several independent mechanisms and is effective even in cells from SMA patients non-responsive to valproate.
    Human molecular genetics, 2009, Oct-01, Volume: 18, Issue:19

    Topics: Animals; Cells, Cultured; Fibroblasts; Gene Expression; Humans; Hydroxamic Acids; Indoles; Mice; Mice, Knockout; Mice, Transgenic; Muscular Atrophy, Spinal; Panobinostat; Survival of Motor Neuron 2 Protein; Valproic Acid

2009
Addition of a histone deacetylase inhibitor redirects tamoxifen-treated breast cancer cells into apoptosis, which is opposed by the induction of autophagy.
    Breast cancer research and treatment, 2011, Volume: 130, Issue:2

    Topics: Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Breast Neoplasms; Cell Line, Tumor; Drug Synergism; Estradiol; Estrogen Receptor alpha; Female; Gene Expression; Gene Knockdown Techniques; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Indoles; Membrane Proteins; Microtubule-Associated Proteins; Panobinostat; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Signal Transduction; Tamoxifen; Valproic Acid; Vorinostat

2011
Histone deacetylase inhibitors induce growth arrest and differentiation in uveal melanoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2012, Jan-15, Volume: 18, Issue:2

    Topics: Animals; Antineoplastic Agents; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Chemoradiotherapy, Adjuvant; Computer Simulation; Gene Knockdown Techniques; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Indoles; Melanoma; Mice; Mice, Inbred NOD; Mice, SCID; Models, Biological; Neoplasm Micrometastasis; Panobinostat; Tumor Burden; Tumor Suppressor Proteins; Ubiquitin Thiolesterase; Uveal Neoplasms; Valproic Acid; Vorinostat; Xenograft Model Antitumor Assays

2012
Establishment and Characterization of Long-Term Cultures Derived from Primary Acute Myeloid Leukemia Cells for HDAC Inhibitor Research.
    Methods in molecular biology (Clifton, N.J.), 2017, Volume: 1510

    Topics: Antigens, CD34; Apoptosis; Biomarkers, Tumor; Cell Culture Techniques; Cell Proliferation; Cell Separation; Cytokines; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Hydroxamic Acids; Indoles; Inhibitor of Apoptosis Proteins; Leukemia, Myeloid, Acute; Neoplastic Stem Cells; Panobinostat; Primary Cell Culture; Signal Transduction; Survivin; Tumor Cells, Cultured; Valproic Acid; Vorinostat

2017
How to Distinguish Between the Activity of HDAC1-3 and HDAC6 with Western Blot.
    Methods in molecular biology (Clifton, N.J.), 2017, Volume: 1510

    Topics: Acetylation; Animals; Benzamides; Blotting, Western; Cell Line, Tumor; Epigenesis, Genetic; Epithelial Cells; Histone Deacetylase 1; Histone Deacetylase 2; Histone Deacetylase 6; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Humans; Hydroxamic Acids; Indoles; Mice; Monocytes; Panobinostat; Protein Processing, Post-Translational; Pyridines; Valproic Acid

2017
Combination treatment of acute myeloid leukemia cells with DNMT and HDAC inhibitors: predominant synergistic gene downregulation associated with gene body demethylation.
    Leukemia, 2019, Volume: 33, Issue:4

    Topics: Biomarkers, Tumor; Decitabine; Demethylation; DNA Methylation; DNA Modification Methylases; Down-Regulation; Drug Synergism; Enzyme Inhibitors; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Humans; Leukemia, Myeloid, Acute; Panobinostat; Valproic Acid

2019