valproic acid and nortriptyline

valproic acid has been researched along with nortriptyline in 20 studies

Research

Studies (20)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (5.00)	18.7374
1990's	4 (20.00)	18.2507
2000's	9 (45.00)	29.6817
2010's	6 (30.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Strassburg, CP; Tukey, RH	1
Topliss, JG; Yoshida, F	1
Chang, TK; Ensom, MH; Kiang, TK	1
Dansette, PM; Fontana, E; Poli, SM	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Lombardo, F; Obach, RS; Waters, NJ	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Glen, RC; Lowe, R; Mitchell, JB	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y	1
Allers, G; Bertschy, G; Jounet, JM; Vandel, S	1
Fu, C; Goldbloom, DS; Katzman, M	1
Awni, WM; Cavanaugh, J; Granneman, GR; Shi, H; Wong, SL	1
Kaplan, B; Swain, RA	1
Borgherini, G; Conforti, D; Fiorellini Bernardis, LA; Magni, G	1
Jain, V; Swartz, CM	1

Reviews

5 review(s) available for valproic acid and nortriptyline

Article	Year
Human UDP-glucuronosyltransferases: metabolism, expression, and disease. Annual review of pharmacology and toxicology, 2000, Volume: 40 Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic	2000
UDP-glucuronosyltransferases and clinical drug-drug interactions. Pharmacology & therapeutics, 2005, Volume: 106, Issue:1 Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic	2005
Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity. Current drug metabolism, 2005, Volume: 6, Issue:5 Topics: Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Humans; Isoenzymes; Structure-Activity Relationship; Terminology as Topic	2005
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Diagnosis, prophylaxis, and treatment of headaches in the athlete. Southern medical journal, 1997, Volume: 90, Issue:9 Topics: Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents, Tricyclic; Chronic Disease; Cluster Headache; Dihydroergotamine; Female; GABA Agents; Headache; Humans; Male; Migraine Disorders; Nortriptyline; Physical Exertion; Psychomotor Performance; Recurrence; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists; Sports; Sumatriptan; Tension-Type Headache; Valproic Acid; Vasodilator Agents; Verapamil	1997

Other Studies

15 other study(ies) available for valproic acid and nortriptyline

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Predicting phospholipidosis using machine learning. Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5 Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine	2010
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships. Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16 Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone	2016
Valpromide increases the plasma concentrations of amitriptyline and its metabolite nortriptyline in depressive patients. Therapeutic drug monitoring, 1988, Volume: 10, Issue:4 Topics: Adult; Amitriptyline; Anticonvulsants; Depressive Disorder; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Nortriptyline; Valproic Acid	1988
Valproate/nortriptyline interaction. Journal of clinical psychopharmacology, 1994, Volume: 14, Issue:3 Topics: Adult; Bipolar Disorder; Drug Interactions; Drug Therapy, Combination; Female; Humans; Male; Nortriptyline; Valproic Acid	1994
Effects of divalproex sodium on amitriptyline and nortriptyline pharmacokinetics. Clinical pharmacology and therapeutics, 1996, Volume: 60, Issue:1 Topics: Adult; Amitriptyline; Anticonvulsants; Antidepressive Agents, Tricyclic; Cytochrome P-450 Enzyme System; Drug Interactions; Female; Humans; Male; Middle Aged; Nortriptyline; Valproic Acid	1996
Extrapyramidal symptoms associated with the adjunct of nortriptyline to a venlafaxine-valproic acid combination. International clinical psychopharmacology, 1999, Volume: 14, Issue:3 Topics: Aged; Anticonvulsants; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Basal Ganglia Diseases; Bipolar Disorder; Cyclohexanols; Drug Combinations; Drug Interactions; Humans; Male; Nortriptyline; Valproic Acid; Venlafaxine Hydrochloride	1999
Charcoal enhancement of treatment for tricyclic-induced mania. Pharmacopsychiatry, 2002, Volume: 35, Issue:5 Topics: Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Antidotes; Bipolar Disorder; Charcoal; Depressive Disorder; Drug Overdose; Female; Humans; Nortriptyline; Treatment Outcome; Valproic Acid	2002