valproic acid and nimodipine

valproic acid has been researched along with nimodipine in 25 studies

Research

Studies (25)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (4.00)	18.7374
1990's	7 (28.00)	18.2507
2000's	11 (44.00)	29.6817
2010's	6 (24.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Bruno-Blanch, L; Gálvez, J; García-Domenech, R	1
Jolivette, LJ; Ward, KW	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
Cuddon, P; Fleming, A; Floto, RA; Goldsmith, P; Jahreiss, L; O'Kane, CJ; Pask, D; Rubinsztein, DC; Saiki, S; Sarkar, S; Siddiqi, FH; Ttofi, EK; Williams, A	1
Lombardo, F; Obach, RS; Waters, NJ	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
De Sarro, A; De Sarro, GB; Nistico', G; Trimarchi, GR	1
Baasch, H; Barzaghi, N; Caresia, L; Galimberti, CA; Gatti, G; Manni, R; Mück, W; Parietti, L; Tartara, A; Zucca, C	1
Ovcharov, R; Surcheva, S	1
Brudniak, T; Czuczwar, SJ; Gasior, M; Kamiński, R; Kleinrok, Z	1
Balakrishnan, S; Bhargava, VK; Pandhi, P	2
Balakrishnan, S; Pandhi, P	1
Dormehl, IC; Oliver, DW	1
Poon, WS; Wong, GK	1
Antonucci, F; Bozzi, Y; Braida, D; Caleo, M; Clerici, M; Corradini, I; De Astis, S; Donzelli, A; Frassoni, C; Inverardi, F; Lipp, HP; Loos, M; Martucci, R; Matteoli, M; Pattini, L; Sala, M; Verderio, C; Welzl, H; Wolfer, D	1

Reviews

1 review(s) available for valproic acid and nimodipine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

1 trial(s) available for valproic acid and nimodipine

Article	Year
Differential effects of valproic acid and enzyme-inducing anticonvulsants on nimodipine pharmacokinetics in epileptic patients. British journal of clinical pharmacology, 1991, Volume: 32, Issue:3 Topics: Adult; Anticonvulsants; Drug Interactions; Enzyme Induction; Epilepsy; Female; Half-Life; Humans; Male; Microsomes, Liver; Nimodipine; Valproic Acid	1991

Other Studies

23 other study(ies) available for valproic acid and nimodipine

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity. Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16 Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship	2003
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure. Journal of pharmaceutical sciences, 2005, Volume: 94, Issue:7 Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution	2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Novel targets for Huntington's disease in an mTOR-independent autophagy pathway. Nature chemical biology, 2008, Volume: 4, Issue:5 Topics: Animals; Autophagy; Calcium Channels, L-Type; Clonidine; Cyclic AMP; Humans; Huntington Disease; Imidazoline Receptors; Minoxidil; Protein Kinases; Signal Transduction; TOR Serine-Threonine Kinases; Type C Phospholipases; Verapamil	2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Effects of some calcium antagonists upon the activity of common antiepileptic compounds on sound-induced seizures in DBA/2 mice. General pharmacology, 1992, Volume: 23, Issue:1 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Anticonvulsants; Body Temperature; Calcium Channel Blockers; Diltiazem; Drug Synergism; Flunarizine; Mice; Mice, Inbred DBA; Nimodipine; Phenobarbital; Phenytoin; Seizures; Valproic Acid; Verapamil	1992
[Effect of sodium valproate and nimodipine on learning in rats during cold exposure]. Eksperimentalna meditsina i morfologiia, 1988, Volume: 27, Issue:2 Topics: Animals; Cold Temperature; Conditioning, Classical; Drug Interactions; Learning; Male; Nimodipine; Rats; Rats, Inbred Strains; Valproic Acid	1988
Influence of nicardipine, nimodipine and flunarizine on the anticonvulsant efficacy of antiepileptics against pentylenetetrazol in mice. Journal of neural transmission (Vienna, Austria : 1996), 1996, Volume: 103, Issue:7 Topics: Animals; Anticonvulsants; Calcium Channel Blockers; Clonazepam; Drug Interactions; Ethosuximide; Flunarizine; Male; Mice; Mice, Inbred Strains; Motor Activity; Nicardipine; Nimodipine; Pentylenetetrazole; Random Allocation; Seizures; Valproic Acid	1996
Effect of nimodipine on the efficacy of commonly used antiepileptic drugs in rats. Indian journal of experimental biology, 1998, Volume: 36, Issue:1 Topics: Animals; Anticonvulsants; Calcium Channel Blockers; Drug Synergism; Electroshock; Female; Male; Nimodipine; Phenytoin; Rats; Seizures; Valproic Acid	1998
Effect of nimodipine on the cognitive dysfunction induced by phenytoin and valproate in rats. Methods and findings in experimental and clinical pharmacology, 1997, Volume: 19, Issue:10 Topics: Animals; Avoidance Learning; Female; Male; Memory Disorders; Nimodipine; Phenytoin; Rats; Retention, Psychology; Valproic Acid	1997
Cerebral blood flow effects of sodium valproate in drug combinations in the baboon model. Arzneimittel-Forschung, 1998, Volume: 48, Issue:11 Topics: Acetazolamide; Animals; Anticonvulsants; Carbonic Anhydrase Inhibitors; Cerebrovascular Circulation; Drug Interactions; Hemodynamics; Male; Nimodipine; Papio; Radiopharmaceuticals; Sumatriptan; Technetium Tc 99m Exametazime; Tomography, Emission-Computed, Single-Photon; Valproic Acid; Vasoconstrictor Agents; Vasodilator Agents	1998
Anticonvulsant profile of nimodipine and nitrendipine against pentylenetetrazole induced seizures in rats. Indian journal of experimental biology, 1999, Volume: 37, Issue:4 Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Male; Nimodipine; Nitrendipine; Pentylenetetrazole; Rats; Seizures; Valproic Acid	1999
Use of phenytoin and other anticonvulsant prophylaxis in patients with aneurysmal subarachnoid hemorrhage. Stroke, 2005, Volume: 36, Issue:12 Topics: Cognition Disorders; Drug Interactions; Humans; Intracranial Aneurysm; Nimodipine; Phenytoin; Seizures; Subarachnoid Hemorrhage; Valproic Acid	2005
Epileptiform activity and cognitive deficits in SNAP-25(+/-) mice are normalized by antiepileptic drugs. Cerebral cortex (New York, N.Y. : 1991), 2014, Volume: 24, Issue:2 Topics: Animals; Anticonvulsants; Association Learning; Brain; Carbamazepine; Cognition Disorders; Epilepsy; Ethosuximide; Hyperkinesis; Kainic Acid; Male; Memory Disorders; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurons; Nimodipine; Seizures; Synaptosomal-Associated Protein 25; Valproic Acid	2014