valproic acid and naloxone

valproic acid has been researched along with naloxone in 40 studies

Research

Studies (40)

Timeframe	Studies, this research(%)	All Research%
pre-1990	16 (40.00)	18.7374
1990's	6 (15.00)	18.2507
2000's	14 (35.00)	29.6817
2010's	4 (10.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Strassburg, CP; Tukey, RH	1
Topliss, JG; Yoshida, F	1
Chang, TK; Ensom, MH; Kiang, TK	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
Lombardo, F; Obach, RS; Waters, NJ	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Bruinvels, J; de Boer, T; Metselaar, HJ	1
Sherard, ES; Steiman, GS; Woerpel, RW	1
Alberto, G; Erickson, T; Hryhorczuk, D; Narayanan, M; Popiel, R	1
Maitre, M; Vayer, P	1
Bianconi, L; Castelli, A; Chiodera, P; d'Amato, L; Gnudi, A; Marchesi, C; Minelli, R; Muzzetto, P; Pioli, G; Volpi, R	1
Gobaille, S; Maitre, M; Mandel, P; Vayer, P	1
Brucato, AF; Cannizzaro, G; Provenzano, PM	1
Ascher, MS; Elias, AN; Iyer, K; Kyaw, T; Stone, S; Weathersbee, P	1
Cannizzaro, G; Flugy, A; Novara, V; Provenzano, PM	1
Cupello, A; Hydén, H; Palm, A	1
Kazandjian, A; Spyraki, C; Varonos, D	1
Elias, AN; Gwinup, G; Valenta, LJ	1
Morag, M; Myslobodsky, MS	1
Contreras, E; Tamayo, L	1
DeFeudis, FV; Jadot, G; Mandel, P; Mesdjian, E; Valli, M	1
Cowan, A	1
Fassos, FF; Mucha, RF; Perl, FM	1
Caffarri, G; Caiazza, A; Capretti, L; Chiodera, P; Coiro, V; Colla, R; Maffei, ML; Volpi, R	1
Alfano, F; Caffarri, G; Caiazza, A; Capretti, L; Chiodera, P; Coiro, V; Maffei, ML; Pagani, D; Papadia, C; Volpi, R	1
Bocchi, R; Caffarri, G; Capretti, L; Chiodera, P; Coiro, V; Marcato, A; Rossi, G; Volpi, R	1
Eric-Marinkovic, J; Grossman, A; Popovic, V; Spremovic-Radjenovic, S	1
Montero, FJ	1
Espinoza, O; Maradei, I; Pascuzzo-Lima, C; Ramírez, M	1
Hicks, LK; McFarlane, PA	1
Francis, EH; Roberge, RJ	1
Barrueto, F; Nelson, LS; Su, M	1
Bowers, JB; Houghton, BL	1
Thanacoody, HK	1
Tabano, C	1
Espinosa, JL; Martinez Miguel, P; Rodriguez Puyol, D; Samillán, K; Sencion Martinez, GL; Villa, P	1

Reviews

5 review(s) available for valproic acid and naloxone

Article	Year
Human UDP-glucuronosyltransferases: metabolism, expression, and disease. Annual review of pharmacology and toxicology, 2000, Volume: 40 Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic	2000
UDP-glucuronosyltransferases and clinical drug-drug interactions. Pharmacology & therapeutics, 2005, Volume: 106, Issue:1 Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic	2005
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Valproic acid overdose and haemodialysis. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2001, Volume: 16, Issue:7 Topics: Bipolar Disorder; Female; Glasgow Coma Scale; Humans; Middle Aged; Naloxone; Poisoning; Renal Dialysis; Suicide, Attempted; Valproic Acid	2001
Use of naloxone in valproic acid overdose: case report and review. The Journal of emergency medicine, 2002, Volume: 22, Issue:1 Topics: Adult; Anticonvulsants; Drug Overdose; Female; Humans; Naloxone; Narcotic Antagonists; Valproic Acid	2002

Trials

1 trial(s) available for valproic acid and naloxone

Article	Year
Opioid modulation of the gamma-aminobutyric acid-controlled inhibition of exercise-stimulated growth hormone and prolactin secretion in normal men. European journal of endocrinology, 1994, Volume: 131, Issue:1 Topics: Adult; Analysis of Variance; Exercise; gamma-Aminobutyric Acid; Growth Hormone; Humans; Male; Naloxone; Prolactin; Reference Values; Valproic Acid	1994

Other Studies

34 other study(ies) available for valproic acid and naloxone

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
Suppression of GABA-induced abstinence behaviour in naive rats by morphine and bicuculline. Life sciences, 1977, Mar-15, Volume: 20, Issue:6 Topics: Aminobutyrates; Animals; Behavior, Animal; Bicuculline; Dose-Response Relationship, Drug; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Isoquinolines; Male; Morphine; Motor Activity; Naloxone; Rats; Receptors, Drug; Receptors, Opioid; Substance Withdrawal Syndrome; Valerates; Valproic Acid	1977
Treatment of accidental sodium valproate overdose with an opiate antagonist. Annals of neurology, 1979, Volume: 6, Issue:3 Topics: Aminobutyrates; Humans; Infant; Male; Naloxone; Valproic Acid	1979
Central nervous system manifestations of a valproic acid overdose responsive to naloxone. Annals of emergency medicine, 1989, Volume: 18, Issue:8 Topics: Adult; Brain; Charcoal; Consciousness; Humans; Male; Naloxone; Sorbitol; Valproic Acid	1989
Gamma-hydroxybutyrate stimulation of the formation of cyclic GMP and inositol phosphates in rat hippocampal slices. Journal of neurochemistry, 1989, Volume: 52, Issue:5 Topics: Animals; Cyclic GMP; Ethosuximide; Hippocampus; Hydroxybutyrates; Inositol Phosphates; Kinetics; Nalorphine; Naloxone; Pentazocine; Rats; Rats, Inbred Strains; Sodium Oxybate; Sugar Phosphates; Trimethadione; Valproic Acid	1989
Metergoline, naloxone, and sodium valproate did not modify arginine vasopressin response to insulin-induced hypoglycemia in man. Journal of endocrinological investigation, 1988, Volume: 11, Issue:5 Topics: Adrenocorticotropic Hormone; Adult; Arginine Vasopressin; Ergolines; gamma-Aminobutyric Acid; Growth Hormone; Humans; Hypoglycemia; Insulin; Male; Metergoline; Naloxone; Valproic Acid	1988
3'-5' cyclic-guanosine monophosphate increase in rat brain hippocampus after gamma-hydroxybutyrate administration. Prevention by valproate and naloxone. Life sciences, 1987, Aug-03, Volume: 41, Issue:5 Topics: Animals; Cyclic GMP; Hippocampus; Hydroxybutyrates; Kinetics; Male; Naloxone; Rats; Rats, Inbred Strains; Sodium Oxybate; Valproic Acid	1987
Effect of single and repeated treatment of chlordiazepoxide and sodium valproate on water intake in the rat and their influence on the antidipsogenic action of naloxone. Arzneimittel-Forschung, 1986, Volume: 36, Issue:4 Topics: Animals; Chlordiazepoxide; Drinking; Drug Interactions; Male; Naloxone; Rats; Rats, Inbred Strains; Time Factors; Valproic Acid	1986
Interaction between gabaergic and opioid pathways in the regulation of gonadotropin secretion in males. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1986, Volume: 18, Issue:12 Topics: Adult; Endorphins; Follicle Stimulating Hormone; gamma-Aminobutyric Acid; Gonadotropin-Releasing Hormone; Gonadotropins, Pituitary; Humans; Luteinizing Hormone; Male; Naloxone; Valproic Acid	1986
Interaction between naloxone, chlordiazepoxide and valproic acid evaluated by emotional operant behaviour in the rat. Arzneimittel-Forschung, 1987, Volume: 37, Issue:1 Topics: Animals; Chlordiazepoxide; Conditioning, Operant; Emotions; Male; Naloxone; Rats; Rats, Inbred Strains; Reinforcement Schedule; Valproic Acid	1987
Naloxone reverses the inhibition by sodium valproate of GABA transport across the Deiters' neuronal plasma membrane. Annals of neurology, 1987, Volume: 21, Issue:4 Topics: Animals; Cell Membrane; gamma-Aminobutyric Acid; In Vitro Techniques; Naloxone; Rabbits; Valproic Acid; Vestibular Nuclei; Vestibular Nucleus, Lateral	1987
Diazepam-induced place preference conditioning: appetitive and antiaversive properties. Psychopharmacology, 1985, Volume: 87, Issue:2 Topics: Animals; Appetitive Behavior; Avoidance Learning; Cocaine; Conditioning, Operant; Convulsants; Diazepam; Male; Meprobamate; Naloxone; Picrotoxin; Pyrazoles; Rats; Rats, Inbred Strains; Valproic Acid	1985
Effects of valproic acid, naloxone and hydrocortisone in Nelson's syndrome and cushing's disease. Clinical endocrinology, 1981, Volume: 15, Issue:2 Topics: Adrenalectomy; Adrenocorticotropic Hormone; Adult; Cushing Syndrome; Female; Humans; Hydrocortisone; Middle Aged; Naloxone; Nelson Syndrome; Pituitary Neoplasms; Valproic Acid	1981
Pharmacologic analysis of sodium valproate-induced suppression of secondary components of visual evoked potentials in albino rats. Pharmacology, biochemistry, and behavior, 1981, Volume: 15, Issue:5 Topics: Animals; Benzodiazepinones; Convulsants; Drug Interactions; Evoked Potentials, Visual; Female; gamma-Aminobutyric Acid; Male; Naloxone; Pentylenetetrazole; Photic Stimulation; Picrotoxin; Rats; Synaptic Transmission; Time Factors; Valproic Acid	1981
A dual action of valproic acid upon morphine analgesia and morphine withdrawal. Pharmacology, 1983, Volume: 26, Issue:6 Topics: Analgesia; Animals; Brain Chemistry; Female; gamma-Aminobutyric Acid; Humans; Mice; Morphine; Naloxone; Substance Withdrawal Syndrome; Valproic Acid	1983
Antinociceptive action of sodium valproate in the mouse. General pharmacology, 1983, Volume: 14, Issue:6 Topics: Acetates; Analgesics; Animals; Bicuculline; Male; Mice; Naloxone; Reaction Time; Valproic Acid	1983
Interactional studies with sodium valproate and naloxone. Annals of neurology, 1980, Volume: 7, Issue:4 Topics: Animals; Behavior, Animal; Male; Naloxone; Rats; Valproic Acid	1980
Withdrawal-like effects of pentylenetetrazol and valproate in the naive organism: a model of motivation produced by opiate withdrawal? Drug and alcohol dependence, 1995, Volume: 39, Issue:1 Topics: Animals; Avoidance Learning; Conditioning, Classical; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Morphine Dependence; Motivation; Naloxone; Neurologic Examination; Opioid-Related Disorders; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome; Taste; Valproic Acid	1995
Role of GABA and opioids in the regulation of the vasopressin response to physical exercise in normal men. Regulatory peptides, 1993, Nov-19, Volume: 49, Issue:1 Topics: Adult; Arginine Vasopressin; Cardiovascular Physiological Phenomena; Endorphins; Exercise; gamma-Aminobutyric Acid; Humans; Male; Naloxone; Respiration; Valproic Acid	1993
Gamma-aminobutyric acid mediation of the inhibitory effect of endogenous opioids on the arginine vasopressin and oxytocin responses to nicotine from cigarette smoking. Metabolism: clinical and experimental, 1993, Volume: 42, Issue:6 Topics: Adult; Analysis of Variance; Arginine Vasopressin; Drug Interactions; Endorphins; gamma-Aminobutyric Acid; Humans; Male; Naloxone; Nicotine; Oxytocin; Smoking; Valproic Acid	1993
Effect of sodium valproate on luteinizing hormone secretion in pre- and postmenopausal women and its modulation by naloxone infusion. The Journal of clinical endocrinology and metabolism, 1996, Volume: 81, Issue:7 Topics: Adult; Estrogen Replacement Therapy; Female; GABA Agents; Humans; Luteinizing Hormone; Middle Aged; Naloxone; Periodicity; Postmenopause; Premenopause; Valproic Acid	1996
Naloxone in the reversal of coma induced by sodium valproate. Annals of emergency medicine, 1999, Volume: 33, Issue:3 Topics: Adult; Anticonvulsants; Coma; Drug Overdose; Female; Glasgow Coma Scale; Humans; Naloxone; Narcotic Antagonists; Suicide, Attempted; Valproic Acid	1999
An unusual presentation of opioid-like syndrome in pediatric valproic acid poisoning. Veterinary and human toxicology, 2001, Volume: 43, Issue:3 Topics: Child, Preschool; Diagnosis, Differential; Drug Overdose; Gastric Lavage; Humans; Male; Naloxone; Opioid-Related Disorders; Poisoning; Treatment Outcome; Valproic Acid	2001
Valproic acid is a structural analog of GABA that enters various metabolic pathways and has many clinical effects. The Journal of emergency medicine, 2002, Volume: 23, Issue:3 Topics: Anticonvulsants; Drug Overdose; Humans; Naloxone; Narcotic Antagonists; Valproic Acid	2002
Valproic acid overdose: a case report and review of therapy. MedGenMed : Medscape general medicine, 2003, Jan-14, Volume: 5, Issue:1 Topics: Administration, Oral; Adult; Antimanic Agents; Charcoal; Drug Administration Schedule; Drug Overdose; Female; Humans; Injections, Intravenous; Naloxone; Suicide, Attempted; Valproic Acid	2003
Chronic valproic acid intoxication: reversal by naloxone. Emergency medicine journal : EMJ, 2007, Volume: 24, Issue:9 Topics: Aged; Antimanic Agents; Bipolar Disorder; Female; Humans; Naloxone; Narcotic Antagonists; Poisoning; Valproic Acid	2007
'Nother one for Narcan. JEMS : a journal of emergency medical services, 2009, Volume: 34, Issue:1 Topics: Emergency Medical Services; Humans; Naloxone; Narcotic Antagonists; Suicide, Attempted; Valproic Acid	2009
[Hemoperfusion with activated charcoal on valproic acid poisoning. A case report]. Medicina intensiva, 2015, Volume: 39, Issue:7 Topics: Benzodiazepines; Charcoal; Combined Modality Therapy; Depressive Disorder; Drug Overdose; Female; Flumazenil; Hemoperfusion; Humans; Hyperammonemia; Middle Aged; Naloxone; Olanzapine; Paranoid Disorders; Psychotropic Drugs; Respiration, Artificial; Suicide, Attempted; Valproic Acid	2015