valproic acid and methylphenidate

valproic acid has been researched along with methylphenidate in 39 studies

Research

Studies (39)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (2.56)	18.7374
1990's	2 (5.13)	18.2507
2000's	18 (46.15)	29.6817
2010's	15 (38.46)	24.3611
2020's	3 (7.69)	2.80

Authors

Authors	Studies
Abraham, MH; Acree, WE; Ibrahim, A	1
Lombardo, F; Obach, RS; Waters, NJ	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Bruni, J; Somerville, ER	1
Frank, Y	1
Cassidy, SB; Dykens, EM; Koenig, K; Leckman, JF; Martin, A; Schultz, R; State, M	1
Gara, L; Roberts, W	1
Beasley, A; Dafny, N; Swann, A; Yang, P	1
Beasley, A; Dafny, N; Eckermann, K; Swann, A; Yang, P	1
Beasley, A; Dafny, N; Eckermann, K; Gaytan, O; Swann, A; Yang, P	1
Hume, JH; Kowatch, RA; Kromelis, M; Sethuraman, G; Weinberg, WA	1
Cummings, MR; Miller, BD	1
Leisman, G; Pedro, VM	1
Mendhekar, DN	1
Cummins, TK; Kratochvil, CJ; Martin, A; Varley, C	1
Avci, A; Tahiroglu, AY	2
Barzman, DH; Findling, RL	1
Kummer, A; Teixeira, A	1
Blader, JC; Jensen, PS; Kafantaris, V; Pliszka, SR; Schooler, NR	1
Andreatini, R; Barbosa, FJ; Baretta, IP; Boerngen-Lacerda, R; de Almeida, RB; Hesse, B	1
Lance, EI; Shapiro, BK	1
Donmez, A; Isik, B; Orun, E; Sonmez, FM; Tas, T; Yilmaz, AE	1
Tobe, E	1
Bachmann, CJ; Glaeske, G; Hoffmann, F; Kamp-Becker, I; Manthey, T	1
Hsia, Y; Wong, IC	1
Ago, Y; Hara, Y; Hasebe, S; Hashimoto, H; Katashiba, K; Matsuda, T; Onaka, Y; Takano, E; Takuma, K; Taruta, A	1
Asth, L; Gavioli, EC; Lobão-Soares, B; Medeiros, IU; Santos, WB; Silva, EF; Soares-Rachetti, VP; Souza, LS	1
Artola, A; Chiu, CT; Chuang, DM; Cordner, ZA; Hess, EJ; Jenkins, PM; Kim, TY; Nelson, AD; Pletnikov, MM; Ross, CA; Tamashiro, KL; Wang, X; Woolums, BM; Xiong, J; Zaika, N; Zhu, S; Zuo, Y	1
Abraham, EH; Chan, S; Herrmann, N; Lanctôt, KL; Ruthirakuhan, MT	1
Asth, L; Calo', G; Costa, LRF; Gavioli, EC; Holanda, VAD; Pacifico, S; Ruzza, C; Tiago, PRF; Zaveri, NT	1
Choi, J; Joung, YS; Oh, Y	1
Andreatini, R; Gonçalves, PS; Monteiro Pereira, VC; Pesquero, BO; Valentin, DT	1

Reviews

4 review(s) available for valproic acid and methylphenidate

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Pharmacologic management of behavioral instability in medically ill pediatric patients. Current opinion in pediatrics, 2004, Volume: 16, Issue:5 Topics: Adolescent; Adrenergic alpha-Agonists; Aggression; Analgesics, Non-Narcotic; Behavior Therapy; Behavioral Medicine; Benzodiazepines; Carbamazepine; Central Nervous System Stimulants; Child; Clonidine; Diphenhydramine; Histamine H1 Antagonists; Humans; Lithium; Methylphenidate; Psychomotor Agitation; Valproic Acid	2004
Pharmacological treatment of pathologic aggression in children. International review of psychiatry (Abingdon, England), 2008, Volume: 20, Issue:2 Topics: Aggression; Antipsychotic Agents; Benzodiazepines; Central Nervous System Stimulants; Child; Drug Prescriptions; Health Status; Humans; Lithium Carbonate; Methylphenidate; Olanzapine; Risperidone; Time Factors; Valproic Acid; Violence	2008
Pharmacological interventions for apathy in Alzheimer's disease. The Cochrane database of systematic reviews, 2018, May-04, Volume: 5 Topics: Alanine; Alzheimer Disease; Antidepressive Agents; Apathy; Azepines; Benzhydryl Compounds; Biphenyl Compounds; Central Nervous System Stimulants; Cholinesterase Inhibitors; Humans; Methylphenidate; Modafinil; Randomized Controlled Trials as Topic; Sulfonamides; Valproic Acid	2018

Trials

3 trial(s) available for valproic acid and methylphenidate

Article	Year
Visual event related potentials after methylphenidate and sodium valproate in children with attention deficit hyperactivity disorder. Clinical EEG (electroencephalography), 1993, Volume: 24, Issue:1 Topics: Attention Deficit Disorder with Hyperactivity; Child; Electroencephalography; Evoked Potentials, Visual; Female; Humans; Male; Methylphenidate; Photic Stimulation; Signal Processing, Computer-Assisted; Valproic Acid	1993
Combination pharmacotherapy in children and adolescents with bipolar disorder. Biological psychiatry, 2003, Jun-01, Volume: 53, Issue:11 Topics: Adolescent; Antidepressive Agents; Antimanic Agents; Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Bipolar Disorder; Bupropion; Carbamazepine; Central Nervous System Stimulants; Child; Drug Therapy, Combination; Female; Humans; Lithium; Male; Methylphenidate; Prospective Studies; Risperidone; Selective Serotonin Reuptake Inhibitors; Valproic Acid	2003
Adjunctive divalproex versus placebo for children with ADHD and aggression refractory to stimulant monotherapy. The American journal of psychiatry, 2009, Volume: 166, Issue:12 Topics: Adolescent; Aggression; Antimanic Agents; Attention Deficit and Disruptive Behavior Disorders; Attention Deficit Disorder with Hyperactivity; Behavior Therapy; Central Nervous System Stimulants; Child; Combined Modality Therapy; Comorbidity; Conduct Disorder; Dextroamphetamine; Drug Therapy, Combination; Family Therapy; Female; Humans; Male; Methylphenidate; Placebos; Treatment Outcome; Valproic Acid	2009

Other Studies

32 other study(ies) available for valproic acid and methylphenidate

Article	Year
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs. European journal of medicinal chemistry, 2008, Volume: 43, Issue:3 Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization	2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate. Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24 Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility	2010
Tonic status epilepticus presenting as confusional state. Annals of neurology, 1983, Volume: 13, Issue:5 Topics: Adolescent; Cognition Disorders; Confusion; Diazepam; Electroencephalography; Humans; Male; Methylphenidate; Phenobarbital; Phenytoin; Sleep; Status Epilepticus; Valproic Acid	1983
Prader-Willi syndrome. The American journal of psychiatry, 1998, Volume: 155, Issue:9 Topics: Child; Chromosome Deletion; Female; Fluvoxamine; Human Growth Hormone; Humans; In Situ Hybridization; Methylphenidate; Prader-Willi Syndrome; Valproic Acid	1998
Adverse response to methylphenidate in combination with valproic acid. Journal of child and adolescent psychopharmacology, 2000,Spring, Volume: 10, Issue:1 Topics: Anticonvulsants; Attention Deficit Disorder with Hyperactivity; Bruxism; Central Nervous System Stimulants; Child; Child, Preschool; Drug Interactions; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Epilepsy; Female; Humans; Male; Methylphenidate; Valproic Acid	2000
Valproate modulates the expression of methylphenidate (ritalin) sensitization. Brain research, 2000, Aug-25, Volume: 874, Issue:2 Topics: Animals; Behavior, Animal; Drug Administration Schedule; Drug Resistance; GABA Agonists; Male; Methylphenidate; Motor Activity; Rats; Rats, Sprague-Dawley; Stereotyped Behavior; Valproic Acid	2000
Valproate prevents the induction of sensitization to methylphenidate (ritalin) in rats. Brain research, 2000, Dec-29, Volume: 887, Issue:2 Topics: Animals; Drug Interactions; Male; Methylphenidate; Motor Activity; Rats; Rats, Sprague-Dawley; Stereotyped Behavior; Time Factors; Valproic Acid	2000
Methylphenidate sensitization is modulated by valproate. Life sciences, 2001, May-25, Volume: 69, Issue:1 Topics: Animals; Central Nervous System Stimulants; Drug Administration Schedule; GABA Agents; Male; Methylphenidate; Motor Activity; Rats; Rats, Sprague-Dawley; Stereotyped Behavior; Time Factors; Valproic Acid	2001
Hemispheric integrative therapy in Landau-Kleffner syndrome: applications for rehabilitation sciences. The International journal of neuroscience, 2005, Volume: 115, Issue:8 Topics: Adolescent; Anticonvulsants; Brain; Central Nervous System Stimulants; Electroencephalography; Female; Functional Laterality; Humans; Landau-Kleffner Syndrome; Language Disorders; Magnetic Resonance Imaging; Methylphenidate; Seizures; Valproic Acid	2005
Clonidine-induced gynecomastia and hyperprolactinemia in a 6-year-old child. The Journal of clinical psychiatry, 2005, Volume: 66, Issue:12 Topics: Age Factors; Anticonvulsants; Attention Deficit Disorder with Hyperactivity; Child; Clonidine; Comorbidity; Gynecomastia; Humans; Hyperprolactinemia; Male; Methylphenidate; Seizures; Valproic Acid	2005
Less is more: inpatient management of a child with complex pharmacotherapy. Journal of the American Academy of Child and Adolescent Psychiatry, 2006, Volume: 45, Issue:5 Topics: Aggression; Amphetamines; Attention Deficit Disorder with Hyperactivity; Child; Clonidine; Depression; Dibenzothiazepines; Domestic Violence; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Humans; Irritable Mood; Length of Stay; Male; Methylphenidate; Patient Admission; Psychiatric Department, Hospital; Psychomotor Agitation; Psychotropic Drugs; Quetiapine Fumarate; Recurrence; Sertraline; Sleep Initiation and Maintenance Disorders; Substance Withdrawal Syndrome; Valproic Acid	2006
Polypharmacy and EPS in a child; a case report. Psychopharmacology bulletin, 2007, Volume: 40, Issue:2 Topics: Attention Deficit Disorder with Hyperactivity; Benztropine; Bipolar Disorder; Child; Comorbidity; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Female; Humans; Imipramine; Injections, Intramuscular; Methylphenidate; Neurologic Examination; Ocular Motility Disorders; Psychotropic Drugs; Valproic Acid	2007
Imipramine, methylphenidate and valproic acid-related EPS in a child: a case report. The international journal of neuropsychopharmacology, 2007, Volume: 10, Issue:5 Topics: Basal Ganglia Diseases; Child; Female; Humans; Imipramine; Methylphenidate; Valproic Acid	2007
Methylphenidate in attention deficit hyperactivity disorder and bipolar disorder. Australasian psychiatry : bulletin of Royal Australian and New Zealand College of Psychiatrists, 2008, Volume: 16, Issue:6 Topics: Anticonvulsants; Attention Deficit Disorder with Hyperactivity; Bipolar Disorder; Central Nervous System Stimulants; Child; Comorbidity; Drug Therapy, Combination; Humans; Long-Term Care; Male; Methylphenidate; Valproic Acid	2008
Magnesium sulfate and sodium valproate block methylphenidate-induced hyperlocomotion, an animal model of mania. Pharmacological reports : PR, 2011, Volume: 63, Issue:1 Topics: Animals; Anticonvulsants; Antimanic Agents; Bipolar Disorder; Central Nervous System Stimulants; Disease Models, Animal; Dose-Response Relationship, Drug; Magnesium Sulfate; Male; Methylphenidate; Mice; Motor Activity; Valproic Acid	2011
Confounding diagnoses in the neurodevelopmental disabilities population: a child with hearing loss, absence epilepsy, and attention-deficit hyperactivity disorder (ADHD). Journal of child neurology, 2013, Volume: 28, Issue:5 Topics: Anticonvulsants; Attention Deficit Disorder with Hyperactivity; Audiometry, Pure-Tone; Central Nervous System Stimulants; Child; Combined Modality Therapy; Developmental Disabilities; Diagnosis, Differential; Electroencephalography; Epilepsy, Absence; Epilepsy, Generalized; Hearing Aids; Hearing Loss, Sensorineural; Humans; Male; Methylphenidate; Signal Processing, Computer-Assisted; Valproic Acid	2013
Methylphenidate-induced acute orofacial and extremity dyskinesia. Journal of child neurology, 2013, Volume: 28, Issue:6 Topics: Anticonvulsants; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; Drug Interactions; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Epilepsy, Frontal Lobe; Humans; Male; Meige Syndrome; Methylphenidate; Valproic Acid	2013
Progressive neuropsychiatric and brain abnormalities after smoke inhalation. BMJ case reports, 2012, Aug-08, Volume: 2012 Topics: Activities of Daily Living; Brain; Cognition Disorders; Depressive Disorder, Major; DNA Damage; Fluorodeoxyglucose F18; Fructose; Humans; Male; Memory, Long-Term; Methylphenidate; Middle Aged; Neurodegenerative Diseases; Neuropsychological Tests; Oxidative Stress; Positron-Emission Tomography; Radiopharmaceuticals; Sertraline; Smoke Inhalation Injury; Time Factors; Topiramate; Valproic Acid	2012
Psychopharmacological treatment in children and adolescents with autism spectrum disorders in Germany. Research in developmental disabilities, 2013, Volume: 34, Issue:9 Topics: Adolescent; Anticonvulsants; Antipsychotic Agents; Autistic Disorder; Central Nervous System Stimulants; Child; Child Development Disorders, Pervasive; Child, Preschool; Female; Germany; Humans; Infant; Infant, Newborn; Male; Methylphenidate; Prevalence; Risperidone; United States; Valproic Acid; Young Adult	2013
Authors' response to Bachmann and Hoffman's comments on psychopharmacological prescriptions for people with autism spectrum disorder (ASD): a multinational study. Psychopharmacology, 2015, Volume: 232, Issue:5 Topics: Child Development Disorders, Pervasive; Female; Humans; Male; Methylphenidate; Risperidone; Valproic Acid	2015
Improvement by methylphenidate and atomoxetine of social interaction deficits and recognition memory impairment in a mouse model of valproic acid-induced autism. Autism research : official journal of the International Society for Autism Research, 2016, Volume: 9, Issue:9 Topics: Animals; Atomoxetine Hydrochloride; Autistic Disorder; Behavior, Animal; Dendritic Spines; Disease Models, Animal; Dopamine; Female; Humans; Interpersonal Relations; Male; Methylphenidate; Mice; Mice, Inbred ICR; Norepinephrine; Prefrontal Cortex; Pregnancy; Receptors, Dopamine D1; Recognition, Psychology; Valproic Acid	2016
Lithium and valproate prevent methylphenidate-induced mania-like behaviors in the hole board test. Neuroscience letters, 2016, 08-26, Volume: 629 Topics: Animals; Antimanic Agents; Behavior, Animal; Bipolar Disorder; Central Nervous System Stimulants; Disease Models, Animal; Exploratory Behavior; Lithium; Locomotion; Male; Methylphenidate; Mice; Neuropsychological Tests; Valproic Acid	2016
Genetic disruption of ankyrin-G in adult mouse forebrain causes cortical synapse alteration and behavior reminiscent of bipolar disorder. Proceedings of the National Academy of Sciences of the United States of America, 2017, 09-26, Volume: 114, Issue:39 Topics: Animals; Ankyrins; Bipolar Disorder; Disease Models, Animal; GABAergic Neurons; Lithium; Methylphenidate; Mice; Mice, Inbred C57BL; Mice, Knockout; Potassium Channels, Voltage-Gated; Prosencephalon; Proto-Oncogene Proteins c-fyn; Synapses; Valproic Acid; Voltage-Gated Sodium Channels	2017
Effects of non-peptide nociceptin/orphanin FQ receptor ligands on methylphenidate-induced hyperactivity in mice: Implications for bipolar disorders. Neuropeptides, 2020, Volume: 82 Topics: Animals; Antimanic Agents; Bipolar Disorder; Female; Hyperkinesis; Imidazoles; Methylphenidate; Mice; Nociceptin Receptor; Receptors, Opioid; Spiro Compounds; Valproic Acid	2020
Incidence of Neutropenia with Valproate, Antipsychotics, and ADHD Medication Combination Treatment in Children and Adolescents. Journal of Korean medical science, 2020, Jul-20, Volume: 35, Issue:28 Topics: Adolescent; Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Child; Female; Humans; Incidence; Logistic Models; Male; Methylphenidate; Neutropenia; Retrospective Studies; Valproic Acid	2020
Effect of repeated sodium valproate and topiramate administration on mania‑like behaviors induced by methylphenidate in mice. Acta neurobiologiae experimentalis, 2022, Volume: 82, Issue:4 Topics: Animals; Antimanic Agents; Central Nervous System Stimulants; Mania; Methylphenidate; Mice; Topiramate; Valproic Acid	2022