Compounds > valproic acid

valproic acid and malondialdehyde

valproic acid has been researched along with malondialdehyde in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.33)18.7374
1990's1 (3.33)18.2507
2000's6 (20.00)29.6817
2010's18 (60.00)24.3611
2020's4 (13.33)2.80

Authors

AuthorsStudies
Göbel, U; Schulte-Berbühl, R; von Voss, H1
Ageel, AM; Al-Bekairi, AM; Qureshi, S; Raza, M1
Altunbaşak, S; Anarat, A; Burgut, HR; Yildizaş, D1
Gejyo, F; In, H; Ito, S; Izumi, J; Kanazawa, M; Nakano, M; Ohno, T; Tanaka, H; Ueno, M; Wada, Y; Yahata, K1
Armutcu, F; Gurel, A; Ilhan, A; Iraz, M; Kamisli, S1
Chiarelli, F; Franzoni, E; Manco, R; Scardapane, A; Verrotti, A1
Dirik, E; Kuralay, F; Kurul, SH; Seçkin, E; Yiş, U1
Ari, M; Cağan, E; Doğan, M; Kozan, R; Oktar, S; Peker, E; Söğüt, S1
Jin, PJ; Wang, XC; Wang, Y; Yu, YH; Zhang, M; Zhang, YJ1
Abdel-Rahman, MN; Kabel, AM1
Alev, B; Emekli-Alturfan, E; Koc-Ozturk, L; Oktay, S; Tunali, S; Tunali-Akbay, T; Yanardag, R; Yarat, A1
Sharma, S; Taliyan, R1
Alev, B; Emekli-Alturfan, E; Oktay, S; Ozturk, LK; Tunali, S; Tunali-Akbay, T; Yanardag, R; Yarat, A1
Akindele, AJ; Benebo, AS; Ota, D; Otuguor, E; Singh, D1
Carvalho, AF; Cavalcante, LM; de Araújo, MM; de Góis Queiroz, AI; de Lucena, DF; de Souza, GC; Gomes, JA; Macêdo, D; Machado, Mde J; Monte, AS; Quevedo, J1
Ghosal, C; Joseph, A; Kamath, SU; Kandwal, M; Kumar, S; Naduvil Narayanan, S; Nayak, BS; Rao, KR; Sahoo, P; Snehunsu, A; Srinivasan, KK; Yadav, PK1
Khongrum, J; Wattanathorn, J1
Hu, XY; Jiang, XH; Liu, D; Qiu, HM; Yang, JX; Zhou, QX1
Cao, Y; Gao, J; Liang, S; Sun, H; Wang, H; Wang, X; Wang, Y; Wu, L; Yang, F; Zhang, F1
Aebischer, B; Akboga, MK; Akdamar, G; Alcalay, RN; Álvarez-Pérez, S; Aydogdu, S; Balci, KG; Barcaro, G; Bišová, K; Blanco, JL; Brewer, SH; Caruthers, SD; Ceylan, O; Chadwick, JA; Chang, DD; Che, JM; Chen, QQ; Chen, W; Chen, Z; Chung, M; Chung, W; Colecraft, HM; Coteli, E; Dogan, H; Dong, S; Elsig, S; Fahn, S; Fang, XJ; Feng, MG; Fenlon, EE; Floyd, KT; Fokdal, L; Ford, B; Fortunelli, A; Freudenberg, R; Gan-Or, Z; García, ME; Gillham, C; Giovannelli, D; Goertz, RS; Gulati, V; Haie-Meder, C; Hao, YY; Hatano, K; Hines, KJ; Hines, SM; Hirakawa, H; Hoskin, P; Hu, JH; Huang, P; Huang, Y; Hubicka, U; Inoue, Y; Ishii, N; Janssen, PM; Jin, Z; Johnson, A; Jürgenliemk-Schultz, I; Kaineder, K; Kamei, K; Kang, U; Karatas, F; Kash, TL; Katayama, Y; Keupp, J; Kirisits, C; Kisacik, H; Kodama, K; Kotzerke, J; Kryczyk, A; Kuhness, D; Kuo, S; Lanza, GM; Le Bris, N; Levin, DE; Levy, OA; Li, B; Li, H; Li, X; Liang, GD; Liang, Y; Liao, RQ; Lin, JT; Lindegaard, JC; Liong, C; Liu, B; Liu, C; Liu, GH; Liu, L; Liu, Q; Liu, X; Lowe, J; Lowery-Gionta, EG; Ma, YH; Maden, O; Mankad, V; Marder, KS; Marshall, SA; Martínez-Nevado, E; Maucksch, U; Mazeron, R; Mazzone, CM; Mazzoni, P; Mezricky, D; Mizokami, Y; Naumann, A; Navarro, M; Netzer, FP; Neurath, MF; Nie, Q; Oliva, P; Ozeke, O; Peláez, T; Pfeifer, L; Pleil, KE; Pomp, S; Pötter, R; Puckerin, AA; Rafael-Fortney, JA; Raman, SV; Rastogi, N; Řezanka, M; Řezanka, T; Rinker, JA; Rouleau, GA; Runge, R; Sahin, MD; Sakai, A; Schmieder, AH; Schmitz, AJ; Schultz, EJ; Šegedin, B; Sementa, L; Shen, Y; Shiotsuki, I; Shirahama, M; Staley, J; Starovoytov, V; Sterrer, M; Strobel, D; Sturdza, A; Subramanyam, P; Surnev, S; Swager, SA; Taeymans, J; Tan, H; Tan, LT; Tanderup, K; Temizhan, A; Terao, T; Thiele, TE; Tran, T; Tucker, MJ; Vetriani, C; Vítová, M; Wang, JP; Wang, L; Wang, M; Wang, X; Waters, CH; Weng, SX; Wickline, SA; Wildner, D; Wodarcyk, AJ; Wolf, P; Wu, L; Wu, YL; Wunderlich, G; Xiong, L; Xu, P; Yang, GS; Yang, XN; Yang, Y; Yayla, C; Ying, SH; Zachleder, V; Zhang, XG; Zhang, XK; Zhang, Y; Zheng, JY; Zhong, WZ; Zhu, J; Zhu, YJ; Żmudzki, P1
Gupta, YK; Kakkar, AK; Kumar, R; Sarangi, SC1
Atef, H; El-Khouly, OA; Nazmy, EA; Said, E1
Cui, W; Wen, X; Zhai, Q; Zhang, T; Zhang, Y1
Gad, AM1
Al-Houqani, M; Azimullah, S; Eissa, N; Jalal, FY; Jayaprakash, P; Kieć-Kononowicz, K; Ojha, SK; Sadek, B; Łażewska, D1
Albayrak, P; Deda, G; Doğan, Ö; Eminoglu, FT; Haznedar, P; Öz Tunçer, G; Teber, S1
Buyuk, B; Coskun, O; Ovali, MA; Oztopuz, O; Sehitoglu, MH; Turkon, H; Uzun, M1
Agarwal, A; Arora, R; Ganeshan N, S; Gupta, YK; Kaleekal, T; Kumar, R; Sarangi, SC1
Ates, B; Colak, C; Gunata, M; Koroglu, OF; Parlakpinar, H; Tanriverdi, LH; Vardi, N; Yildiz, A1
Ahmed, MM; Alsemeh, AE; Fawzy, A; Rezq, S; Samy, W; Tharwat, M1

Reviews

1 review(s) available for valproic acid and malondialdehyde

ArticleYear
    Hand therapy, 2016, Volume: 21, Issue:1

    Topics: AC133 Antigen; Acenaphthenes; Acer; Acrosome Reaction; Adult; Agaricales; Aged; Aged, 80 and over; Animals; Animals, Zoo; Anti-Bacterial Agents; Anticoagulants; Antifungal Agents; Antimanic Agents; Antioxidants; Aortic Valve; Area Under Curve; ATP Binding Cassette Transporter, Subfamily G, Member 2; Bacillus; Bacterial Toxins; Bacterial Typing Techniques; Base Composition; Beauveria; Binge Drinking; Biomarkers; Bipolar Disorder; Blood Coagulation; Blotting, Western; Brachytherapy; Calcium Channels, L-Type; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Cell Wall; Cells, Cultured; Ceramics; Chi-Square Distribution; China; Chlorophyll; Chlorophyta; Chloroplasts; Cholesterol, HDL; Chromatography, High Pressure Liquid; Chromobacterium; Clostridium perfringens; Clozapine; Constriction, Pathologic; Coronary Artery Bypass; Corticotropin-Releasing Hormone; Cross-Sectional Studies; Cytochrome P-450 CYP2C9; Dental Porcelain; Dental Restoration Failure; Dental Stress Analysis; Designer Drugs; Diaminopimelic Acid; DNA Fingerprinting; DNA, Bacterial; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Dosage Calculations; Drug Evaluation, Preclinical; Drug Resistance, Bacterial; Elasticity Imaging Techniques; Epsilonproteobacteria; Equipment Design; Ericaceae; Excitatory Amino Acid Antagonists; False Negative Reactions; Fatty Acids; Female; Food Analysis; Fresh Water; Gene Expression Regulation, Neoplastic; Glutathione; Graft Occlusion, Vascular; Heart Valve Prosthesis Implantation; Heart Ventricles; HEK293 Cells; Hemolymph; Humans; Hyaluronan Receptors; Hydrogen Peroxide; Hydrothermal Vents; Indoles; Inflammation Mediators; Inhibitory Concentration 50; Insecta; International Normalized Ratio; Isotope Labeling; Itraconazole; Kidney; Kinetics; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Lamotrigine; Lanthanoid Series Elements; Limit of Detection; Linear Models; Lipid Peroxidation; Liver; Liver Cirrhosis; Logistic Models; Lung Neoplasms; Lymph Node Excision; Lymphatic Metastasis; Male; Malondialdehyde; Mediastinum; Metronidazole; Mice; Mice, Nude; Mice, Transgenic; Microbial Sensitivity Tests; Microscopy, Fluorescence; Middle Aged; Monocytes; Monomeric GTP-Binding Proteins; Multivariate Analysis; Myocytes, Cardiac; Neoplasm Staging; Neoplastic Stem Cells; Neural Pathways; Nitrates; Nucleic Acid Hybridization; Octamer Transcription Factor-3; Odds Ratio; Oxidation-Reduction; Oxidative Stress; Peptidoglycan; Phantoms, Imaging; Pharmacogenetics; Pharmacogenomic Variants; Phenotype; Phospholipids; Photolysis; Photosynthesis; Phylogeny; Plant Extracts; Polychaeta; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Positron Emission Tomography Computed Tomography; Predictive Value of Tests; Preoperative Care; Prostatic Neoplasms; Pseudomonas aeruginosa; Pyrimidines; Pyrroles; Quorum Sensing; Radiology, Interventional; Radiopharmaceuticals; Radiotherapy Dosage; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Reference Values; Regression Analysis; Retrospective Studies; Reverse Transcriptase Polymerase Chain Reaction; Rhizosphere; Risk Factors; RNA, Ribosomal, 16S; ROC Curve; Rutin; Saphenous Vein; Seawater; Selenium; Semen Preservation; Sensitivity and Specificity; Septal Nuclei; Sequence Analysis, DNA; Serum Albumin; Serum Albumin, Human; Shear Strength; Sodium Pertechnetate Tc 99m; Sodium-Hydrogen Exchangers; Soil Microbiology; SOXB1 Transcription Factors; Spain; Species Specificity; Sperm Motility; Spermatozoa; Spheroids, Cellular; Spores, Fungal; Stroke; Superoxide Dismutase; Swine; Tandem Mass Spectrometry; Technetium Compounds; Technetium Tc 99m Exametazime; Technetium Tc 99m Sestamibi; Temperature; Thiosulfates; Thrombosis; Thyroid Neoplasms; Transducers; Transfection; Transplantation, Heterologous; Treatment Outcome; Triazines; Tumor Burden; Urocortins; Uterine Cervical Neoplasms; Vacuoles; Valproic Acid; Ventral Tegmental Area; Vitamin K 2; Vitamin K Epoxide Reductases; Warfarin; Water Microbiology; Young Adult

2016

Trials

1 trial(s) available for valproic acid and malondialdehyde

ArticleYear
Renal tubular dysfunction in epileptic children on valproic acid therapy.
    Pediatric nephrology (Berlin, Germany), 2001, Volume: 16, Issue:3

    Topics: Acetylglucosamine; Adolescent; Anticonvulsants; beta 2-Microglobulin; Child; Cross-Sectional Studies; Epilepsy; Fanconi Syndrome; Female; Humans; Kidney Function Tests; Kidney Tubules; Longitudinal Studies; Male; Malondialdehyde; Valproic Acid

2001

Other Studies

28 other study(ies) available for valproic acid and malondialdehyde

ArticleYear
Side effects of sodium valproate (sodium di-N-propylacetate) on malonyldialdehyde-production and other platelet function tests.
    Minerva pediatrica, 1978, Sep-15, Volume: 30, Issue:17

    Topics: Adult; Blood Platelet Disorders; Blood Platelets; Child; Epilepsy; Factor IX; Factor VIII; Fibrinogen; Humans; Malonates; Malondialdehyde; Prothrombin; Thrombin; Valproic Acid

1978
Biochemical basis of sodium valproate hepatotoxicity and renal tubular disorder: time dependence of peroxidative injury.
    Pharmacological research, 1997, Volume: 35, Issue:2

    Topics: Animals; Anticonvulsants; Chemical and Drug Induced Liver Injury; Glutathione; Kidney; Kidney Diseases; Kidney Tubules; Lipid Peroxidation; Male; Malondialdehyde; Mice; Time Factors; Valproic Acid

1997
Mixed connective tissue disease associated with antineutrophil cytoplasmic antibodies against proteinase-3 and systemic atherosclerosis: a case report.
    Clinical rheumatology, 2004, Volume: 23, Issue:5

    Topics: Antibodies, Antineutrophil Cytoplasmic; Arteriosclerosis; Aspirin; Autoantibodies; Cholesterol, LDL; Female; Granulomatosis with Polyangiitis; Humans; Lipid Peroxidation; Malondialdehyde; Middle Aged; Mixed Connective Tissue Disease; Myeloblastin; Prednisolone; Probucol; Serine Endopeptidases; Treatment Outcome; Valproic Acid

2004
Antiepileptogenic and antioxidant effects of Nigella sativa oil against pentylenetetrazol-induced kindling in mice.
    Neuropharmacology, 2005, Volume: 49, Issue:4

    Topics: Adenosine Deaminase; Analysis of Variance; Animals; Anticonvulsants; Antioxidants; Dose-Response Relationship, Drug; Drug Interactions; Glutathione Peroxidase; Kindling, Neurologic; Male; Malondialdehyde; Mice; Nitric Oxide; Pentylenetetrazole; Plant Oils; Seizures; Time Factors; Valproic Acid; Xanthine Oxidase

2005
Increased oxidative stress in epileptic children treated with valproic acid.
    Epilepsy research, 2008, Volume: 78, Issue:2-3

    Topics: Anthropometry; Anticonvulsants; Antioxidants; Blood Chemical Analysis; Blood Glucose; Child; Epilepsy, Generalized; Female; Humans; Insulin; Lipid Peroxidation; Lipoproteins, LDL; Male; Malondialdehyde; Obesity; Oxidative Stress; Prospective Studies; Valproic Acid; Vitamin E

2008
Effects of epilepsy and valproic acid on oxidant status in children with idiopathic epilepsy.
    Epilepsy research, 2009, Volume: 84, Issue:2-3

    Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Epilepsy; Erythrocytes; Female; Glutathione Peroxidase; Humans; Infant; Lipid Peroxidation; Male; Malondialdehyde; Oxidative Stress; Superoxide Dismutase; Valproic Acid

2009
Nitric oxide, lipid peroxidation, and antioxidant enzyme levels in epileptic children using valproic acid.
    Brain research, 2009, Nov-10, Volume: 1297

    Topics: Anticonvulsants; Antioxidants; Biomarkers; Catalase; Child; Child, Preschool; Enzyme Assays; Enzymes; Epilepsy; Female; Humans; Lipid Peroxidation; Male; Malondialdehyde; Nitric Oxide; Oxidation-Reduction; Oxidative Stress; Spectrophotometry; Superoxide Dismutase; Valproic Acid

2009
[Effects of sodium valproate on neutrophils' oxidative metabolism and oxidant status in children with idiopathic epilepsy].
    Zhonghua er ke za zhi = Chinese journal of pediatrics, 2011, Volume: 49, Issue:10

    Topics: Anticonvulsants; Antioxidants; Case-Control Studies; Catalase; Child; Child, Preschool; Epilepsy; Female; Glutathione Peroxidase; Humans; Lipid Peroxidation; Male; Malondialdehyde; Neutrophils; Oxidative Stress; Superoxide Dismutase; Valproic Acid

2011
Comparative study between the effect of methotrexate and valproic acid on solid Ehrlich tumour.
    Journal of the Egyptian National Cancer Institute, 2012, Volume: 24, Issue:4

    Topics: Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Ehrlich Tumor; Catalase; Cholesterol; Drug Screening Assays, Antitumor; Glutathione Peroxidase; Malondialdehyde; Methotrexate; Mice; Neoplasm Transplantation; Tumor Burden; Tumor Necrosis Factor-alpha; Tumor Suppressor Protein p53; Valproic Acid

2012
Edaravone ameliorates the adverse effects of valproic acid toxicity in small intestine.
    Human & experimental toxicology, 2015, Volume: 34, Issue:6

    Topics: Alkaline Phosphatase; Animals; Antipyrine; Edaravone; Female; Free Radical Scavengers; Glutathione; Glutathione Peroxidase; Glutathione Transferase; Intestine, Small; Malondialdehyde; N-Acetylneuraminic Acid; Peroxidase; Rats, Sprague-Dawley; Superoxide Dismutase; Thromboplastin; Valproic Acid

2015
Synergistic effects of GSK-3β and HDAC inhibitors in intracerebroventricular streptozotocin-induced cognitive deficits in rats.
    Naunyn-Schmiedeberg's archives of pharmacology, 2015, Volume: 388, Issue:3

    Topics: Acetylcholinesterase; Animals; Avoidance Learning; Brain; Brain-Derived Neurotrophic Factor; Cognition Disorders; Drug Synergism; Drug Therapy, Combination; Glutathione; Glycogen Synthase Kinase 3; Histone Deacetylase Inhibitors; Insulin; Lithium Chloride; Malondialdehyde; Memory; Memory Disorders; Neuroprotective Agents; Nitrates; Nitrites; Rats, Wistar; Spatial Learning; Streptozocin; Valproic Acid

2015
Effects of edaravone on cardiac damage in valproic acid induced toxicity.
    Annals of clinical and laboratory science, 2015,Spring, Volume: 45, Issue:2

    Topics: Alkaline Phosphatase; Animals; Antipyrine; Catalase; Edaravone; Female; Glutathione; Glutathione Peroxidase; Glutathione Transferase; Lipid Peroxidation; Malondialdehyde; Myocardium; N-Acetylneuraminic Acid; Peroxidase; Rats; Sodium-Potassium-Exchanging ATPase; Superoxide Dismutase; Thromboplastin; Valproic Acid

2015
Hypoglycemic, antilipidemic and antioxidant effects of valproic acid in alloxan-induced diabetic rats.
    European journal of pharmacology, 2015, Sep-05, Volume: 762

    Topics: Animals; Antioxidants; Blood Glucose; Body Weight; Calcium; Cytosol; Diabetes Mellitus, Experimental; Drinking; Hydrogen Peroxide; Hypoglycemic Agents; Hypolipidemic Agents; Insulin-Secreting Cells; Kidney; Lipids; Liver; Male; Malondialdehyde; Organ Size; Rats; Rats, Wistar; Valproic Acid

2015
Preclinical Evidences for an Antimanic Effect of Carvedilol.
    Neural plasticity, 2015, Volume: 2015

    Topics: Adrenergic beta-Antagonists; Animals; Antimanic Agents; Bipolar Disorder; Brain; Brain-Derived Neurotrophic Factor; Carbazoles; Carvedilol; Glutathione; Hippocampus; Lipid Peroxidation; Lisdexamfetamine Dimesylate; Male; Malondialdehyde; Motor Activity; Propanolamines; Rats; Rats, Wistar; Social Isolation; Valproic Acid

2015
1-Triacontanol cerotate; isolated from Marsilea quadrifolia Linn. ameliorates reactive oxidative damage in the frontal cortex and hippocampus of chronic epileptic rats.
    Journal of ethnopharmacology, 2015, Aug-22, Volume: 172

    Topics: Animals; Chronic Disease; Dose-Response Relationship, Drug; Epilepsy, Generalized; Fatty Alcohols; Frontal Lobe; Glutathione; Hippocampus; Malondialdehyde; Marsileaceae; Oxidative Stress; Pentylenetetrazole; Rats; Valproic Acid

2015
Laser Acupuncture Improves Behavioral Disorders and Brain Oxidative Stress Status in the Valproic Acid Rat Model of Autism.
    Journal of acupuncture and meridian studies, 2015, Volume: 8, Issue:4

    Topics: Acupuncture Points; Acupuncture Therapy; Animals; Autistic Disorder; Brain; Catalase; Disease Models, Animal; Female; Humans; Lasers; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase; Valproic Acid

2015
Enhancing tyrosine hydroxylase and tryptophan hydroxylase expression and improving oxidative stress involved in the antidepressant effect of sodium valproate on rats undergoing chronic unpredicted stress.
    Neuroreport, 2015, Dec-16, Volume: 26, Issue:18

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Catalase; Depression; Male; Malondialdehyde; Oxidative Stress; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; RNA, Messenger; Stress, Psychological; Superoxide Dismutase; Tryptophan Hydroxylase; Tyrosine 3-Monooxygenase; Valproic Acid

2015
Neuroprotective effects of docosahexaenoic acid on hippocampal cell death and learning and memory impairments in a valproic acid-induced rat autism model.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2016, Volume: 49

    Topics: Animals; Anticonvulsants; Autistic Disorder; Caspase 3; Cell Death; Disease Models, Animal; Docosahexaenoic Acids; Female; Glutathione Peroxidase; Hippocampus; Learning Disabilities; Male; Malondialdehyde; Maze Learning; Memory Disorders; Neuroprotective Agents; Phosphopyruvate Hydratase; Rats; Rats, Wistar; Superoxide Dismutase; Valproic Acid

2016
Effect of lamotrigine, levetiracetam & topiramate on neurobehavioural parameters & oxidative stress in comparison with valproate in rats.
    The Indian journal of medical research, 2016, Volume: 144, Issue:1

    Topics: Animals; Brain; Fructose; Glutathione; Lamotrigine; Learning; Levetiracetam; Male; Malondialdehyde; Memory; Oxidative Stress; Piracetam; Rats; Superoxide Dismutase; Topiramate; Triazines; Valproic Acid

2016
Sulforaphane protects against sodium valproate-induced acute liver injury.
    Canadian journal of physiology and pharmacology, 2017, Volume: 95, Issue:4

    Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Anticarcinogenic Agents; Anticonvulsants; Antioxidants; Aspartate Aminotransferases; Biomarkers; Brassica; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Drug Evaluation, Preclinical; Epilepsy; Glutathione; Heme Oxygenase-1; Humans; Isothiocyanates; Liver Function Tests; Male; Malondialdehyde; Phytochemicals; Rats; Rats, Sprague-Dawley; Sulfoxides; Tumor Necrosis Factor-alpha; Valproic Acid

2017
N-acetylcysteine ameliorates repetitive/stereotypic behavior due to its antioxidant properties without activation of the canonical Wnt pathway in a valproic acid-induced rat model of autism.
    Molecular medicine reports, 2017, Volume: 16, Issue:2

    Topics: Acetylcysteine; Animals; Antioxidants; Autistic Disorder; Behavior, Animal; beta Catenin; Brain; Glutathione; Glycogen Synthase Kinase 3 beta; Male; Malondialdehyde; Oxidative Stress; Phosphorylation; Rats; Rats, Sprague-Dawley; Valproic Acid; Wnt Signaling Pathway

2017
Study on the influence of caffeic acid against sodium valproate-induced nephrotoxicity in rats.
    Journal of biochemical and molecular toxicology, 2018, Volume: 32, Issue:8

    Topics: Animals; Anticonvulsants; Biomarkers; Caffeic Acids; Caspase 3; Creatinine; Inflammation; Interferon-gamma; Kidney; Male; Malondialdehyde; NF-kappa B; Nitric Oxide Synthase Type II; Rats, Sprague-Dawley; Receptors, Notch; Signal Transduction; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha; Urea; Valproic Acid

2018
The histamine H3R antagonist DL77 attenuates autistic behaviors in a prenatal valproic acid-induced mouse model of autism.
    Scientific reports, 2018, 08-30, Volume: 8, Issue:1

    Topics: Animals; Anxiety; Autistic Disorder; Behavior, Animal; Brain; Choice Behavior; Cytokines; Disease Models, Animal; Donepezil; Exploratory Behavior; Female; Histamine H3 Antagonists; Inflammation Mediators; Malondialdehyde; Maze Learning; Mice; Motor Activity; Oxidative Stress; Phenyl Ethers; Piperidines; Receptors, Histamine H3; Social Behavior; Stereotyped Behavior; Valproic Acid

2018
Effects of levetiracetam and valproic acid treatment on liver function tests, plasma free carnitine and lipid peroxidation in childhood epilepsies.
    Epilepsy research, 2019, Volume: 153

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Anticonvulsants; Carnitine; Child; Deoxyguanosine; Epilepsy; Female; Humans; Levetiracetam; Lipid Peroxidation; Liver; Liver Function Tests; Male; Malondialdehyde; Retrospective Studies; Thiobarbituric Acid Reactive Substances; Valproic Acid

2019
Melatonin ameliorates sodium valproate-induced hepatotoxicity in rats.
    Molecular biology reports, 2020, Volume: 47, Issue:1

    Topics: Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Glutathione; Glutathione Peroxidase; Glutathione Transferase; Hepatocytes; Isoenzymes; Lipid Peroxidation; Liver; Male; Malondialdehyde; Melatonin; NF-kappa B; Oxidative Stress; Peroxidase; Rats; Rats, Wistar; Superoxide Dismutase; Valproic Acid

2020
Pharmacodynamic and pharmacokinetic interactions of hydroalcoholic leaf extract of Centella asiatica with valproate and phenytoin in experimental models of epilepsy in rats.
    Journal of ethnopharmacology, 2021, Apr-24, Volume: 270

    Topics: Adjuvants, Pharmaceutic; Animals; Anticonvulsants; Behavior, Animal; Centella; Cognitive Dysfunction; Cytochrome P-450 Enzyme Inhibitors; Disease Models, Animal; Electroshock; Epilepsy; Glutathione; Herb-Drug Interactions; Malondialdehyde; Medicine, Ayurvedic; Methanol; Oxidative Stress; Pentylenetetrazole; Phenytoin; Plant Extracts; Plant Leaves; Rats, Wistar; Seizures; Valproic Acid

2021
Protective effects of naringin on valproic acid-induced hepatotoxicity in rats.
    Tissue & cell, 2021, Volume: 72

    Topics: Animals; Body Weight; Catalase; Chemical and Drug Induced Liver Injury; Flavanones; Glutathione; Liver; Liver Function Tests; Malondialdehyde; Organ Size; Protective Agents; Rats, Wistar; Superoxide Dismutase; Valproic Acid

2021
Vitamin E rescues valproic acid-induced testicular injury in rats: Role of autophagy.
    Life sciences, 2022, May-01, Volume: 296

    Topics: AMP-Activated Protein Kinases; Animals; Autophagy; Beclin-1; Catalase; Gene Expression Regulation; Male; Malondialdehyde; Microtubule-Associated Proteins; Rats; Sperm Motility; Superoxide Dismutase; Testis; Testosterone; TOR Serine-Threonine Kinases; Valproic Acid; Vitamin E

2022