valproic acid has been researched along with lithium in 467 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (4.28) | 18.7374 |
| 1990's | 122 (26.12) | 18.2507 |
| 2000's | 179 (38.33) | 29.6817 |
| 2010's | 96 (20.56) | 24.3611 |
| 2020's | 50 (10.71) | 2.80 |
| Authors | Studies |
|---|---|
| Chauvot, B; Maés, L; Pascalis, G | 1 |
| Semadeni, GW | 1 |
| Villeneuve, A | 1 |
| Motohashi, N | 1 |
| Clothier, J; Freeman, T; Swann, AC | 1 |
| Gerner, RH; Stanton, A | 1 |
| Mosolov, SN | 1 |
| Cullen, MJ; Mitchell, P | 1 |
| Mitchell, PB; Parker, GB | 1 |
| Brown, G; Ellicott, A; Gitlin, M; Hammen, C; Jamison, K | 1 |
| McFarland, BH; Miller, MR; Straumfjord, AA | 1 |
| Alpert, JE; Frankenburg, FR; Hudson, JI; Keck, PE; Strakowski, SM; Teschke, GC; Tohen, M; Wilson, DR | 1 |
| Ahlers, AA; Nielsen, C | 1 |
| Calabrese, JR; Delucchi, GA | 2 |
| Altamura, AC; Mauri, MC; Percudani, M; Regazzetti, MG | 1 |
| Post, RM | 2 |
| Coplan, JD; Gorman, JM | 1 |
| Hayes, SG | 1 |
| Cookson, JC | 1 |
| Borsook, D; Brennan, MJ; Moore-Ede, MC; Richardson, GS | 1 |
| Hudson, JI; Pope, HG | 1 |
| Baciewicz, AM | 1 |
| Lovett, L; Shaw, DM; Watkins, SE | 1 |
| Schou, M | 2 |
| Rogers, J; Troost, BT; Williams, DP | 1 |
| Shukla, GS | 1 |
| Jähkel, M; Oehler, J; Schmidt, J | 1 |
| Dose, M; Emrich, HM; Günther, R | 1 |
| Cordero, JF; Oakley, GP | 1 |
| Soucek, K; Vencovský, E; Zatecká, I | 1 |
| Berrettini, W; Kellner, C; Post, RM; Uhde, TW | 1 |
| Emrich, HM; Kissling, W; Möller, HJ; von Zerssen, D; Windorfer, A | 1 |
| Parthasarathy, R; Vadnal, R | 1 |
| Blum, LD | 1 |
| Werder, SF | 1 |
| Costello, LE; Suppes, T | 1 |
| DasGupta, K; Jefferson, JW | 1 |
| Gross, R; Grunhaus, L | 1 |
| Calabrese, JR; Woyshville, MJ | 2 |
| Brady, KT; Sonne, SC | 1 |
| Bowden, CL | 7 |
| Byerly, MJ; Evans, DL; Greer, RA | 1 |
| Swann, AC | 3 |
| Chou, JC; Sweeney, EA; Tuma, I | 1 |
| Mielke, DH | 1 |
| Hickie, I; Jacobs, G; Mitchell, P; Withers, K | 1 |
| Risby, ED; Risch, SC; Risinger, RC | 1 |
| Fawcett, J; Kravitz, HM | 1 |
| Joffe, RT | 1 |
| Collacott, RA; Cooper, SA | 1 |
| Lagomarsino, AJ | 1 |
| Fawcett, J; Schaff, MR; Zajecka, JM | 1 |
| Kirch, DG; Li, R; Wing, LL; Wyatt, RJ | 1 |
| Ikeda, R | 1 |
| McCoy, L; Nasrallah, HA; Schwarzkopf, SB; Votolato, NA | 1 |
| Calabrese, JR; Kimmel, SE; Rapport, DJ; Reece, B; Woyshville, MJ | 1 |
| Altshuler, LL; Finch, NN; Frye, MA; Mintz, J; Szuba, MP | 1 |
| Beattie, M; Buxton, E; Dangel, C; Fenn, HH; Kraemer, H; Luby, V; Robinson, D; Yesavage, JA | 1 |
| Pollack, MH; Worthington, JJ | 1 |
| Cavanaugh, JH; Granneman, GR; Schneck, DW; Witt, GF | 1 |
| Bennett, JA; Chmiel, JJ; Henke, CJ; Keck, PE; Nabulsi, AA; Stanton, SP; Taylor, JL | 1 |
| Rush, AJ; Suppes, T | 1 |
| Keck, PE; McElroy, SL | 3 |
| Calabrese, JR; Fatemi, SH; Kujawa, M; Woyshville, MJ | 1 |
| Locke, CA; Mayer, PV; Stoll, AL; Vuckovic, A | 1 |
| Prien, RF; Rush, AJ | 1 |
| McDonald, WM; Nemeroff, CB | 1 |
| Dixon, JF; Hokin, LE; Los, GV | 1 |
| Barros, HM; Tannhauser, M; Tannhauser, SL; Vargas, C | 1 |
| Charles, G; Emilien, G; Maloteaux, JM; Seghers, A | 1 |
| Post, RM; Weiss, SR | 1 |
| DeVane, CL; Finkenbine, RD; McKinney, PA | 1 |
| Bennett, JA; Keck, PE; McElroy, SL | 2 |
| Chen, G; Hsiao, JK; Manji, HK; Masana, MI; Potter, WZ; Risby, ED | 1 |
| Chaney, KA; Chen, J; Rasenick, MM | 1 |
| Keitner, GI; Miller, IW; Ryan, CE; Solomon, DA | 1 |
| Bowden, CL; Calabrese, JR; Davis, JM; Dilsaver, SC; Morris, D; Petty, F; Small, J; Swann, AC | 1 |
| Baldassano, CF; Ghaemi, SN; Sachs, GS; Truman, CJ | 1 |
| Dixon, JF; Hokin, LE | 1 |
| Godleski, LS; Griffin, RA; Mazure, CM; Sernyak, MJ; Woods, SW | 1 |
| Swartz, CM; Townes, P | 1 |
| Longhurst, JG | 1 |
| Ali, SO; Bryan, AL; Denicoff, KD; Post, RM; Smith-Jackson, EE | 1 |
| Bowden, CL; Calabrese, J; Davis, J; Goodnick, P; Lambert, M; Morris, D; Swann, A | 1 |
| Dardennes, RM; Even, C | 1 |
| Freeman, MP; Stoll, AL | 1 |
| Calabrese, JR; Fatemi, SH; Rapport, DJ; Thuras, P | 1 |
| DeGolia, SG; Dunai, M; Ketter, TA; Strong, CM; Tate, DL; Winsberg, ME | 1 |
| Kraemer, HC; Rush, AJ; Suppes, T; Webb, A | 1 |
| Baker, CB; Sernyak, MJ; Woods, SW | 1 |
| Garno, JL; Goldberg, JF; Kocsis, JH; Leon, AC; Portera, L | 2 |
| Greenfield, SF; Griffin, ML; Najavits, LM; Soto, JA; Tohen, M; Weiss, RD; Wyner, D | 1 |
| Licht, RW | 1 |
| Evans, DL; Murphy, TK; Tueth, MJ | 1 |
| Boerlin, HL; Gitlin, MJ; Hammen, CL; Zoellner, LA | 1 |
| Sanderson, DR | 1 |
| Hagan, RM; Higgins, GA; Kirkby, D; Southam, E | 1 |
| Woods, SW | 1 |
| Biederman, J; Bostic, JQ; Daly, J; Faraone, SV; Garcia-Jetton, J; Mick, E; Prince, J; Russell, R; Spencer, T; Wilens, TE; Wozniak, J | 1 |
| Dardennes, R; Even, C | 1 |
| Chen, G; Huang, LD; Jiang, YM; Manji, HK; Yuan, PX; Zeng, WZ; Zhao, ZH | 1 |
| Bown, C; Wang, JF; Young, LT | 1 |
| Bebchuk, JM; Chen, G; Glitz, D; Hasanat, KA; Manji, HK; Moore, GJ | 1 |
| Goodwin, FK | 1 |
| Austin, MP; Mitchell, PB | 1 |
| Bourin, M; Redrobe, JP | 1 |
| Grundy, S; Tohen, M | 1 |
| Shelton, RC | 1 |
| Altshuler, LL; Chen, ST; Erhart, SM; Melnyk, KA; Miller, E; Mintz, J | 1 |
| Cress, KK; Diamond, E; Freeman, MP; Marangell, LB; Rueter, S; Severus, WE; Stoll, AL; Zboyan, HA | 1 |
| Freeman, MP | 1 |
| Conney, J; Kaston, B | 1 |
| Lovell, RW | 1 |
| Corá-Locatelli, G; Frye, MA; Ketter, TA; Kimbrell, TA; Post, RM | 1 |
| Kupfer, DJ; Marcus, SC; Olfson, M; Pincus, HA; Zarin, DA | 1 |
| Cott, AD; Wisner, KL | 1 |
| DeBattista, C; Schatzberg, AF | 1 |
| Caretto, J; Schaffer, CB; Schaffer, LC | 1 |
| Bowden, CL; Calabrese, JR; Dilsaver, SC; Morris, DD; Swann, AC | 3 |
| Lubrich, B; van Calker, D | 1 |
| Ali, SO; Bryan, AL; Denicoff, KD; Frye, MA; Goldstein, TR; Leverich, GS; Post, RM; Smith-Jackson, E | 1 |
| Jope, RS; Pacheco, MA | 1 |
| Tyrer, SP; Vanstraelen, M | 1 |
| Bowers, MB; Fazeli, A; Mazure, CM; McKay, BG; Preda, A | 1 |
| Lenox, RH; Manji, HK | 2 |
| Centeno, F; Fuentes, JM; González-Polo, RA; Mora, A; Soler, G | 1 |
| Amann, B; Erfurth, A; Grunze, H; Marcuse, A; Normann, C; Walden, J | 1 |
| Hoenderboom, AC; Kupka, RW; Nolen, WA; Oostervink, F | 1 |
| Chaudron, LH; Jefferson, JW | 1 |
| Pearlstein, T | 1 |
| Khan, T; Lippmann, S; Mercke, Y; Sheng, H | 1 |
| Altshuler, LL; Burt, VK; Gudeman, D; Hendrick, V; Korenman, S; Rasgon, NL; Tanavoli, S | 1 |
| Gershon, S; Soares, JC | 1 |
| Goldberg, JF; Kocsis, JH; Sacks, MH | 1 |
| Greenberg, ML; Murray, M | 1 |
| Bucci, JP; Carmody, TJ; Emslie, GJ; Hume, JH; Kowatch, RA; Kromelis, M; Rush, AJ; Suppes, T; Weinberg, WA | 1 |
| Baker, CB; Dalkilic, A; Diaz, E; Pearsall, HR; Woods, SW | 1 |
| Griswold, KS; Pessar, LF | 1 |
| Ghaemi, SN; Guille, C; Sachs, GS | 1 |
| Chen, G; Manji, HK; Moore, GJ | 1 |
| Nemeroff, CB | 1 |
| Brady, KT | 1 |
| Ghaemi, SN | 1 |
| Benedek, DM; Flynn, J; Grieger, TA | 1 |
| Buttenfield, J; Chengappa, KN; Gershon, S; Hardan, A; Kupfer, DJ; Levine, J; Luther, J; Mallinger, AG; Pollock, B; Vagnucci, A; Verfaille, S | 1 |
| Atzert, R; Brar, JS; Chengappa, KN; Delaney, J; Levin, H; Levine, J; Moffa, N; Parepally, H; Rathore, D; Solai, L | 1 |
| Ding, D; Greenberg, ML; Peterson, B; Vaden, DL | 1 |
| Blankesteijn, WM; Cleutjens, JP; Smits, JF; Snel, F; van Gijn, ME | 1 |
| Gundlapalli, SP; Iqbal, MM; Passman, TE; Ryals, T; Ryan, WG | 1 |
| Green, M; Hua, LV; Li, PP; Warsh, JJ | 1 |
| Bell, JM; Chang, MC; Contreras, MA; Rapoport, SI; Rintala, JJ; Rosenberger, TA | 1 |
| Chang, KD; Ketter, TA | 1 |
| Bowden, CL; Evans, DL; Gergel, IP; Gyulai, L; Nemeroff, CB; Oakes, R; Pitts, CD; Sachs, GS | 1 |
| Bowden, CL; Caban, SJ; Calabrese, JR; Kimmel, SE; Rapport, DJ; Shelton, MD; Shirley, ER; Suppes, T | 1 |
| Guenther, MG; Huang, EY; Klein, PS; Lazar, MA; Phiel, CJ; Zhang, F | 1 |
| Grace, JJ; Narendran, R; Pato, MT; Pristach, CA; Valenti, AM; Young, CM | 1 |
| Iqbal, MM; Mahmud, SZ; Sohhan, T | 1 |
| Ahrens, B; Becker, T; Roick, C | 1 |
| Patrick, G; Reeves, RR; Struve, FA | 1 |
| Bingham, CR; Brescan, DW; DiGiovanni, SK; Hattab, H; Perez, DE; Ray, JB; Sajatovic, M | 1 |
| Geddes, JR; Goodwin, GM; Haslam, DR; Macritchie, KA; Scott, J | 1 |
| Ferrier, IN | 1 |
| Hardy-Baylé, MC | 1 |
| Belmaker, RH; Ding, D; Greenberg, ML; Ju, S; Shaldubina, A; Vaden, DL | 1 |
| Chuang, DM; Hashimoto, R; Hough, C; Nakazawa, T; Yamamoto, T | 1 |
| Calabrese, JR; Ketter, TA | 1 |
| Ketter, TA; Wang, PW | 1 |
| Chengappa, KN; Gershon, S; Levine, J | 1 |
| Cheng, L; Harwood, AJ; Mudge, AW; Williams, RS | 1 |
| Pope, M; Scott, J | 1 |
| Meyer, JM | 1 |
| Bosetti, F; Rapoport, SI | 1 |
| Bowden, CL; Ghaemi, SN; Grossman, F; Okamoto, A; Sachs, GS | 1 |
| Brennan, A; Cleverley, K; Goold, RG; Gordon-Weeks, PR; Hall, AC; Lucas, FR; Salinas, PC | 1 |
| Frye, MA; Ketter, TA; Li, X | 1 |
| Hollander, E; Pallanti, S; Quercioli, L; Sood, E | 1 |
| Alonso, JC; Centeno, F; Mora, A; Sabio, G; Soler, G | 1 |
| el-Mailakh, RS; el-Masri, MA; Hennion, JP; Huff, MO | 1 |
| Cohen, D; Flament, MF; Gérardin, P; Mazet, P | 1 |
| Sajatovic, M | 1 |
| Bowley, MP; Drevets, WC; Ongür, D; Price, JL | 1 |
| Fernandez-Corres, B; Gonzalez-Pinto, A; Gutierrez, M; Lalaguna, B; Micó, JA; Pérez-Heredia, JL; Tohen, M | 1 |
| Gould, TD; Manji, HK | 2 |
| Asghar, SJ; Hanstock, CC; O'Donnell, T; Silverstone, PH; Ulrich, M; Wu, RH | 2 |
| Gurvich, N; Klein, PS | 1 |
| Brar, JS; Chalasani, L; Chengappa, KN; Houck, P; Levine, J; Parepally, H | 1 |
| Agam, G; Greenberg, ML; Shaltiel, G; Shamir, A | 1 |
| Geddes, JR | 1 |
| Atmanspacher, R; Moser, D; Spleiss, O; van Calker, D; Wiesmann, K; Willmroth, F | 1 |
| Berghöfer, AM; Hartikainen, J; Reischies, FM | 1 |
| Ding, D; Greenberg, ML | 1 |
| Loy, R; Tariot, PN | 1 |
| Berghöfer, A; Hartikainen, J; Reischies, FM | 1 |
| Ernst, CL; Goldberg, JF | 1 |
| Bown, CD; Wang, JF; Young, LT | 1 |
| Du, J; Gray, NA; Manji, HK; Moore, GJ; Zhou, R | 1 |
| Dunner, DL | 1 |
| Hanstock, CC; Nakashima, TT; O'Donnell, T; Rotzinger, S; Silverstone, PH; Ulrich, M | 2 |
| Bowden, CL; Calabrese, JR; Chou, JC; Evans, DL; Gyulai, L; Hirschfeld, RM; Keck, PE; McElroy, SL; Nemeroff, CB; Petty, F; Risch, CS; Swann, AC; Wassef, A; Wozniak, PJ | 1 |
| Hume, JH; Kowatch, RA; Kromelis, M; Sethuraman, G; Weinberg, WA | 1 |
| Akundi, RS; Fiebich, BL; Hamke, M; Lieb, K; Treffurth, Y; von Kleinsorgen, M | 1 |
| Agam, G; Harwood, AJ | 1 |
| Iwazaki, H | 1 |
| Koyama, T; Nakagawa, S | 1 |
| Koyama, T; Suzuki, K | 1 |
| Iyo, M; Nonomura, T | 1 |
| Agam, G; Belmaker, RH; Kozlovsky, N; Nadri, C | 1 |
| Basile, VS; Kennedy, SH; Mancini, DA; McIntyre, RS; Srinivasan, J | 1 |
| Denson, TF; Sokolski, KN | 1 |
| Baker, JD; Hirschfeld, RM; Sommerville, KW; Tracy, K; Wozniak, P | 1 |
| Belin, T; Davanzo, P; Emley-Akanno, C; Gunderson, B; Mintz, J; Montazeri, N; Oppenheimer, J; Ott, D; Pataki, C; Strober, M | 1 |
| Cordeiro, ML; Gundersen, CB; Umbach, JA | 1 |
| Dittmann, S; Grunze, H | 1 |
| Bretschneider, S; Bullacher, Ch; Frasch, K; Hess, R; Neumann, NU; Wittek, R | 1 |
| Benabarre, A; Colom, F; Comes, M; Corbella, B; Goikolea, JM; Martínez-Arán, A; Reinares, M; Sánchez-Moreno, J; Torrent, C; Vieta, E | 1 |
| Chen, G; Du, J; Einat, H; Gould, TD; Manji, HK | 1 |
| Charney, DS; Denicoff, KD; Du, J; Gray, NA; Manji, HK; Quiroz, J; Singh, J; Zarate, CA | 1 |
| Du, J; Falke, C; Gray, NA; Manji, HK; Szabo, S; Yuan, P | 1 |
| Du, J; Falke, CS; Gray, NA; Manji, HK; Yuan, P | 1 |
| Akimoto, T; Koyama, T; Kusumi, I; Sasaki, Y; Suzuki, K | 1 |
| Coffey, B | 1 |
| Burt, VK; Rasgon, N | 1 |
| Shao, L; Sun, X; Wang, JF; Young, LT | 1 |
| Corson, TW; Li, PP; Warsh, JJ; Woo, KK | 1 |
| Baker, RW; Bowden, CL; Calabrese, JR; Chengappa, KN; Evans, AR; Feldman, PD; Ghaemi, SN; Kupfer, DJ; Risser, RC; Sachs, GS; Suppes, T; Tohen, M; Zarate, CA | 1 |
| Bagnall, AM; Bridle, C; Darba, J; Duffy, S; Palmer, S; Riemsma, R; Sculpher, M | 1 |
| Hashimoto, M; Kurita, M; Mashiko, H; Miyashita, N; Niwa, S; Ohtomo, K; Shirakawa, H | 1 |
| Bowden, CL; Grossman, F; Myers, JE; Xie, Y | 1 |
| Brune, K; Fox, N; Li, B; Liu, F; Ni, B; Paul, S; Ryder, J; Solenberg, P; Su, Y; Wu, X; Zhou, Y | 1 |
| Charney, DS; Denicoff, KD; Luckenbaugh, DA; Manji, HK; Payne, JL; Quiroz, JA; Singh, J; Zarate, CA | 1 |
| Kass, E; Klein, RM; Lewis, FT | 1 |
| Ghaemi, SN; Hsu, DJ; Pardo, TB | 1 |
| Basta-Kaim, A; Budziszewska, B; Jaworska-Feil, L; Kubera, M; Lasoń, W; Leśkiewicz, M; Tetich, M | 1 |
| Calabrese, JR; Daniel, DG; Kochan, LD; Swann, AC; Wozniak, PJ | 1 |
| Altshuler, LL; DeAntonio, M; Frye, MA; Hwang, S; Mintz, J; State, RC; Strober, M | 1 |
| Dager, SR; Demopulos, C; Dunner, DL; Friedman, SD; Hirashima, F; Lyoo, IK; Parow, A; Renshaw, PF; Stoll, AL | 1 |
| Cummings, MR; Miller, BD | 1 |
| Oral, ET; Vahip, S | 1 |
| Jainer, AK; Sundararajan, V | 1 |
| Kennedy, SH; Konarski, JZ; Mancini, DA; McCann, S; McIntyre, RS; Srinivasan, J | 1 |
| Mullen, J; Paulsson, B; Vågerö, AM; Yatham, LN | 1 |
| Schatzberg, AF | 1 |
| Geddes, J | 1 |
| Bark, N; Citrome, L; Josiassen, R; Mallikaarjun, S; Salazar, DE | 1 |
| Asghar, SJ; Bell, EC; Dave, S; Silverstone, PH; Willson, MC; Wilman, AH | 1 |
| Chuang, DM; Hiroi, T; Hough, C; Leeds, P; Wei, H | 1 |
| De Sarno, P; Eom, TY; Jope, RS; Roh, MS; Roth, KA; Zmijewska, AA | 1 |
| Wozniak, J | 1 |
| Citrome, L; Goldberg, JF | 1 |
| Dewhurst, S; Jin, N; Kovács, AD; Maggirwar, SB; Sui, Z | 1 |
| Chen, G; Chen, J; Damschroder-Williams, P; Du, J; Gray, NA; Li, X; Manji, HK; Yuan, P; Zhang, L; Zhou, R | 1 |
| Dalton, EC; Harwood, AJ; Jonathan Ryves, W; Williams, RS | 1 |
| Ahearn, EP; Hirschfeld, RM; Keck, PE; Palmer, C; Revicki, DA; Weisler, RH | 1 |
| Asghar, SJ; Bell, EC; Dave, S; McGrath, BM; Silverstone, PH; Willson, MC | 1 |
| Bowden, CL; Calabrese, JR; Collins, MA; McElroy, SL; Swann, AC; Weisler, RH; Wozniak, PJ | 1 |
| Dokucu, ME; Taghert, PH; Yu, L | 1 |
| Shao, L; Wang, JF; Young, LT | 1 |
| Berle, JØ; Spigset, O | 1 |
| Furuichi, T; Tomomura, M | 1 |
| Bell, EC; Dave, S; Silverstone, PH; Willson, MC; Wilman, AH | 1 |
| Brody, SA; Geyer, MA; Large, CH; Ong, JC | 1 |
| Axelson, D; Birmaher, B; Brambilla, P; Hatch, JP; Kaur, S; Keshavan, MS; Monkul, ES; Nicoletti, M; Ryan, N; Sassi, RB; Soares, JC | 1 |
| Chuang, DM | 1 |
| Danielyan, A; Kowatch, RA | 1 |
| Ding, D; Geiger, JH; Greenberg, ML; Ju, S; Shi, Y; Vaden, DL | 1 |
| Adam, MJ; Chinnapalli, M; Lam, RW; Liddle, PF; Ruth, TJ; Solomons, K; Yatham, LN | 1 |
| Schweizer, LM; Schweizer, M; Vavassori, S; Wang, K | 1 |
| Bilali, S; Calabrese, JR; Findling, RL; Ganocy, SJ; Jackson, K; Rapport, DJ; Shelton, MD; Youngstrom, EA | 1 |
| DeCaria, CM; Grant, JE; Hollander, E; Pallanti, S; Urpe, M | 1 |
| Allen, MH; Bowden, CL; Calabrese, JR; Chessick, CA; Endick, CJ; Goldberg, JF; Miklowitz, DA; Miyahara, S; Sachs, GS; Sagduyu, K; Thase, ME; Wisniewski, SR | 1 |
| Durst, R; Raskin, S; Teitelbaum, A; Zislin, J | 1 |
| Calabrese, JR; Demeter, CA; Findling, RL; Gracious, BL; McNamara, NK; Reed, MD; Stansbrey, R; Whipkey, RE; Youngstrom, EA | 1 |
| Alda, M; Goldapple, K; Krüger, S; Mayberg, HS; Parikh, S; Young, LT | 1 |
| Einat, H; Manji, HK | 1 |
| Andreazza, AC; Ceresér, KM; Frey, BN; Kapczinski, F; Martins, MR; Quevedo, J; Réus, GZ; Valvassori, SS | 1 |
| Manji, HK; Singh, J; Zarate, CA | 1 |
| Carlezon, WA; Cohen, BM; Mague, SD; Tomasiewicz, HC | 1 |
| Hellings, JA | 1 |
| Akdeniz, F; Bora, E; Vahip, S | 1 |
| Andreazza, AC; Frey, BN; Hatch, JP; Kapczinski, F; Martins, MR; Quevedo, J; Réus, GZ; Rosa, AR; Valvassori, SS | 1 |
| Ahl, J; Baldessarini, RJ; Houston, JP; Kaiser, CJ; Meyers, AL; Tohen, M | 1 |
| Cui, J; Shao, L; Wang, JF; Young, LT | 1 |
| Barbieri, M; Beynon, S; Bravo Vergel, Y; Duffy, S; Dunn, G; Geddes, J; Gilbody, S; Palmer, S; Soares-Weiser, K; Woolacott, N | 1 |
| Chuang, DM; Leeds, P; Leng, Y; Liang, MH; Marinova, Z; Ren, M | 1 |
| Bazinet, RP; Lee, HJ; Rao, JS; Rapoport, SI | 1 |
| Goldfarb, DS; Hoffman, RS; Holubek, WJ; Nelson, LS | 1 |
| Cheung, NS; Duan, W; Li, QT; Liu, JP; Liu, K; Smith, A; Zhang, W; Zhou, S | 1 |
| Fonseca, SG; Ishigaki, S; Kakiuchi, C; Kato, T; Oslowski, CM; Urano, F | 1 |
| Alesci, S; Bachmann, RF; Du, J; Li, X; Manji, HK; Wang, Y; Yuan, P; Zhou, R | 1 |
| Agam, G; Almog, O; Belmaker, RH; Bersudsky, Y; Heldman, E; Ishikawa, Y; Mann, L; Vatner, SF | 1 |
| Bundo, M; Ishigooka, J; Ishiwata, M; Iwamoto, K; Kakiuchi, C; Kato, T; Sugawara, H; Ueda, J | 1 |
| Bayliss, G | 1 |
| Chuang, DM; Leeds, P; Leng, Y; Tsai, LK; Wang, Z | 1 |
| Cao, X; Liang, Z; Su, Y; Sun, S; Xiao, H | 1 |
| Glue, P; Herbison, P; Tarr, GP | 1 |
| Fisar, Z; Hroudová, J; Raboch, J | 1 |
| Al Jurdi, R; Bruce, ML; Gildengers, A; Greenberg, RL; Mulsant, B; Sajatovic, M; Tenhave, T; Young, RC | 1 |
| Carson, W; Khan, A; Marcus, R; Morris, B; Rollin, L; Sanchez, R; Timko, K | 1 |
| Aggarwal, SK; Li, SC | 1 |
| Chappell, PB; Gurtovaya, O; Ice, KS; Kasuba, B; Sachs, GS; Schwartz, JH; Vanderburg, DG | 1 |
| Burke, AK; Currier, D; Galfalvy, HC; Grunebaum, MF; Harkavy-Friedman, J; Mann, JJ; Oquendo, MA; Parsey, RV; Sher, L; Sublette, ME; Sullivan, GM | 1 |
| Chiu, CT; Chuang, DM; Leeds, P; Liu, G | 1 |
| Albin, RL; Tallaksen-Greene, SJ | 1 |
| Chuang, DM; Leeds, P; Leng, Y; Munasinghe, J; Tsai, LK; Wang, Z | 1 |
| Austin, DR; Catapano, LA; Chen, G; Dosemeci, A; Luckenbaugh, DA; Manji, HK; Markey, SP; Nanavati, D | 1 |
| Perlis, RH | 1 |
| Rushlow, WJ; Sutton, LP | 1 |
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| Ekholm, B; Gustafsson, U; Suppes, T; Vieta, E | 1 |
| Chiu, CT; Chuang, DM; Leeds, P; Tanaka, M; Wang, Z; Yu, F; Zhang, Y | 1 |
| Bahk, WM; Kim, MD; Kwon, YJ; Lee, HB; Lee, JG; Woo, YS; Yoon, BH | 1 |
| Gu, L; Hertz, L; Li, B; Peng, L; Yan, E | 1 |
| Goyal, MK; Kesav, P; Modi, M; Prabhakar, S; Vishnu, VY | 1 |
| Cardoso, MR; Ferreira, GK; Furlanetto, CB; Gonçalves, CL; Jeremias, IC; Quevedo, J; Resende, WR; Rezin, GT; Scaini, G; Streck, EL; Valvassori, SS; Varela, RB | 1 |
| Breman, AM; Chen, H; Cheung, SW; Han, K; Hao, S; Holder, JL; Kang, H; Lu, H; Lu, HC; Patel, A; Schaaf, CP; Sun, H; Tang, J; Wu, Z; Yu, P; Zoghbi, HY | 1 |
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| Ballard, ED; Brutsche, NE; Ionescu, DF; Luckenbaugh, DA; Lundin, NB; Machado-Vieira, R; Niciu, MJ; Richards, EM; Vande Voort, JL; Xu, AJ; Zarate, CA | 1 |
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| Chang, CL; Cheng, C; Chou, PH; Lan, TH; Lin, CH; McInnis, MG; Tsai, CJ | 1 |
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| Coppens, V; Dumont, G; Morrens, M; Sabbe, B; Staels, W; van den Ameele, S; van Diermen, L | 1 |
| Asth, L; Gavioli, EC; Lobão-Soares, B; Medeiros, IU; Santos, WB; Silva, EF; Soares-Rachetti, VP; Souza, LS | 1 |
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| Fischer, HD; Fung, K; Gruneir, A; Herrmann, N; Rej, S; Shulman, K | 1 |
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| Feng, HL; Jiang, HQ; Jiang, HZ; Qi, Y; Wang, J; Wang, SY; Wang, TH; Wang, XD; Wang, Y; Yang, YQ; Yin, X; Zhang, CT | 1 |
| Alam, HB; Allyn-Feuer, A; Athey, BD; Georgoff, P; Higgins, GA; Nikolian, V | 1 |
| Holder, SD | 1 |
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| Araújo, TDS; Carvalho, AF; Chaves Filho, AJM; de Lucena, DF; de Queiroz, AIG; Lima, CNC; Macedo, D; Machado, MJS; Quevedo, J; Vasconcelos, SMM | 1 |
| Adroja, B; Parekh, H; Prakash, S | 1 |
| Artola, A; Chiu, CT; Chuang, DM; Cordner, ZA; Hess, EJ; Jenkins, PM; Kim, TY; Nelson, AD; Pletnikov, MM; Ross, CA; Tamashiro, KL; Wang, X; Woolums, BM; Xiong, J; Zaika, N; Zhu, S; Zuo, Y | 1 |
| Chou, PH; Chu, CS; Lan, TH; Lin, CH | 1 |
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| Hsieh, TC; Lin, CC; Wu, LS | 2 |
| Nurchi, AM; Pinna, AP; Podda, F; Ripoli, C; Tronci, MG; Zanni, R | 1 |
| Bastos, JR; de Miranda, AS; Machado, FS; Marciano Vieira, ÉL; Moreira, FA; Perico, KM; Teixeira, AL | 1 |
| Carvalho, AF; Hidalgo-Mazzei, D; Murru, A; Pacchiarotti, I; Samalin, L; Verdolini, N; Vieta, E; Young, AH | 1 |
| Han, X; Ji, E; Li, L; Qiu, Y; Tang, F; Yang, H; Zhang, S; Zhang, Z | 1 |
| Huang, J; Jia, S; Li, B; Peng, L; Verkhratsky, A | 1 |
| Kelly, E; Sharma, D; Wilkinson, CJ; Williams, RSB | 1 |
| Asth, L; Calo', G; Gavioli, EC; Guerrini, R; Ruzza, C; Silva, AI; Silva, EF; Souza, LS; Zaveri, NT | 1 |
| Bai, Y; Fang, Y; Han, X; Ji, E; Li, L; Peng, D; Tang, F; Yang, H; Zhang, S; Zhang, Z | 1 |
| Fahimeh, J; Mahboobeh, R; Masoud, Y; Mehrnoosh, M; Parastoo, K; Ramin, S | 1 |
| Dixon, S; Garg, AX; Gruneir, A; Herrmann, N; Jandoc, R; McArthur, E; Rej, S | 1 |
| Balasubramanian, D; Kennedy, MA; Pearson, JF | 1 |
| Bertolin, S; Lam, RW; Qian, H; Valdes, M; Wong, H; Yatham, LN | 1 |
| Carmassi, C; Caruso, D; Del Grande, C; Dell'Osso, L; Fagiolini, A; Masci, I; Musetti, L | 1 |
| Alda, M; Corbett, N | 1 |
| Ağaoğlu, E; Ak, S; Anıl Yağcıoğlu, AE; Ertuğrul, A; Karahan, S; Karakaşlı, AA; Yazıcı, MK | 1 |
| Hroudová, J; Ľupták, M | 1 |
| Cheong, JH; Choi, SY; Jang, CG; Jeong, JH; Kim, DW; Kim, HC; Nabeshima, T; Phan, DH; Saito, K; Sharma, N; Shin, EJ; Tran, HQ; Tran, TV | 1 |
| Abulseoud, OA; Camsari, U; Güçlü, O; Schleyer, B; Şenormancı, G; Şenormancı, Ö | 1 |
| Balcioglu, YH; Turan, B; Unal, G | 1 |
| Arnold, JG; Bai, Y; Bowden, CL; Calabrese, JR; Conroy, C; D'Arcangelo, N; Gao, K; Prihoda, TJ; Quinones, M; Schinagle, M; Singh, V | 1 |
| Dixon, S; Garg, AX; Gruneir, A; Harel, Z; Herrmann, N; Jeyakumar, N; McArthur, E; Muanda, FT; Rej, S | 1 |
| Berk, M; Brietzke, E; Goldstein, BI; Kessing, LV; López-Jaramillo, C; Majeed, A; Malhi, GS; Mansur, RB; McIntyre, RS; Nierenberg, AA; Rosenblat, JD; Vieta, E; Vinberg, M; Young, AH | 1 |
| Bauer, M; Bohlken, J; Kostev, K; Riedel-Heller, S | 1 |
| Cree, SL; Kennedy, MA; Miller, AL; Pearson, JF; Sinha, P | 1 |
| Akkouh, IA; Andreassen, OA; de Assis, DR; Djurovic, S; Frei, E; Hughes, T; Osete, JR; Smeland, OB; Steen, NE; Szabo, A | 1 |
| Arnold, I; Dehning, J; Grunze, A; Hausmann, A | 1 |
| Abdelnaim, MA; Deppe, M; Hebel, T; Kreuzer, PM; Langguth, B; Mohonko, A; Poeppl, TB; Rupprecht, R; Schecklmann, M | 1 |
| Salisbury, E; Topp, S | 1 |
| Hatano, M; Ikuta, T; Iwata, N; Kishi, T; Matsuda, Y; Nomura, I; Okuya, M; Sakuma, K | 1 |
| Asp, M; Fernström, J; Grudet, C; Holck, A; Lavant, E; Lindqvist, D; Ohlsson, L; Westrin, Å | 1 |
| Amiriani, T; Dolab, N; Kamkar, MZ; Marjani, A; Marjani, M; Yuzugulen, J | 1 |
| Akbarzadeh, F; Dadgar Moghaddam, M; Eslamzadeh, M; Fayyazi Bordbar, MR; Mokhber, N; Ziaee, M; Zolfaghari, M | 1 |
| Altun, A; Çiçekli, MN; Günaydın, C; Tiryaki, ES | 1 |
| Austin, KL; Kim, HM; Miller, DR; Sauer, BC; Smith, EG; Valenstein, M | 1 |
| Bowden, CL; Calabrese, JR; Friedman, ES; Fung, V; Iosifescu, DV; Ketter, TA; Kocsis, JH; Köhler-Forsberg, O; McElroy, SL; McInnis, M; Nierenberg, AA; Ostacher, MJ; Shelton, RC; Sylvia, LG; Thase, M; Tohen, M | 1 |
| Anyfandi, E; Ferentinos, P; Kalogerakou, S; Nikolakopoulou, M; Owens, DA; Papakosta, VM; Psarros, C; Tsaltas, E | 1 |
| De Picker, LJ; Geddes, JR; Harrison, PJ; Leboyer, M; Morrens, M; Taquet, M | 1 |
| Köhler-Forsberg, O; Nierenberg, AA; Rohde, C; Østergaard, SD | 2 |
| Budtz-Jørgensen, E; Gerds, T; Kessing, LV; Ziersen, SC | 1 |
| Nabekura, T; Uwai, Y | 1 |
| Holm, M; Lähteenvuo, M; Taipale, H; Tanskanen, A; Tiihonen, J | 1 |
| Greenberg, ML; Lazcano, P; Onu, CJ; Schmidtke, MW | 1 |
| Ji, E; Kim, KW; Kwon, JS; Moon, W; Shin, J | 1 |
| Cai, Z; Chen, G; Chen, J; Li, Q; Li, R; Ma, X; Song, X; Tian, H; Xu, Y; Yang, L; Zhang, Q; Zhou, C; Zhuo, C | 1 |
| Cao, D; Hong, Y; Huang, W; Wang, L; Wei, H; Xu, J; Zhang, J | 1 |
| Koponen, M; Lähteenvuo, M; Puranen, A; Taipale, H; Tanskanen, A; Tiihonen, J | 1 |
| Chan, HY; Chen, CC; Chou, FH; Lin, CH | 1 |
| Bodenstein, K; Damba, JJ; Drury, J; Greenway, KT; Lavin, P; Rej, S; Renoux, C; Sekhon, H; Trinh, E | 1 |
| Cantelmi, T; Lepore, E; Unfer, V; Unfer, VR | 1 |
| Chao, G; Jin, Y; Liu, C; Wang, J; Xu, C; Zhou, Q | 1 |
| Davis, RE; Dutheil, S; Snyder, GL; Watson, LS | 1 |
| Chan, HY; Chen, CC; Lin, CH; Lin, HY | 1 |
| Chen, R; Davis, RE; Durgam, S; Kozauer, SG; Lakkis, HD; Mates, S; McIntyre, RS; Satlin, A; Suppes, T; Tohen, M; Vanover, KE | 1 |
| Carli, M; Grenno, G; Kolachalam, S; Longoni, B; Maggio, R; Pardini, C; Ponzini, S; Scarselli, M; Tidona, S; Vaglini, F; Viaggi, C; Weiss, F | 1 |
| El-Mallakh, RS; Elsayed, OH; Pahwa, M | 1 |
| Bocci, G; Calabrò, PF; Carli, M; Fini, E; Natale, G; Scarselli, M | 1 |
| Leopold, S; Quante, A | 1 |
| Chou, PH; Lin, CH; Wang, XY; Yang, CC | 1 |
| Al-Dardery, NM; Attia, AN; Hamad, AA; Meshref, M; Mohamed, SF | 1 |
| Arslan, MA; Bilgici, B; Gümrükçüoğlu, Tİ; Karaustaoğlu, A; Tunçel, ÖK | 1 |
| Chen, W; Chen, Z; Huang, Y; Peng, H; Wang, B; Wang, M; Wang, X; Wu, H | 1 |
| Scarselli, M | 1 |
| Bellocco, R; Bosi, A; Carrero, JJ; Ceriani, L; Chang, Z; Clase, CM; Elinder, CG; Fu, EL; Landén, M; Runesson, B; Sjölander, A | 1 |
| Burke, AK; Dervic, K; Galfalvy, HC; Grunebaum, M; Mann, JJ; Oquendo, MA; Sher, L; Sublette, ME; Sullivan, G | 1 |
138 review(s) available for valproic acid and lithium
| Article | Year |
|---|---|
Treatment of bipolar disorder.
Topics: Anticonvulsants; Bipolar Disorder; Carbamazepine; Humans; Lithium; Valproic Acid | 1991 |
Alternative prophylactic treatments to lithium in bipolar disorders.
Topics: Alprazolam; Bipolar Disorder; Calcium Channel Blockers; Carbamazepine; Clonazepam; Humans; Lithium; Valproic Acid | 1990 |
Non-lithium treatment for bipolar disorder.
Topics: Anticonvulsants; Bipolar Disorder; Carbamazepine; Clinical Trials as Topic; Clonazepam; Drug Therapy, Combination; Humans; Lithium; Lithium Carbonate; Valproic Acid | 1990 |
Treatment of anxiety disorder in patients with mood disorders.
Topics: Antidepressive Agents; Anxiety Disorders; Benzodiazepines; Buspirone; Depressive Disorder; Humans; Lithium; Psychotherapy; Valproic Acid | 1990 |
Emerging perspectives on valproate in affective disorders.
Topics: Adult; Bipolar Disorder; Carbamazepine; Drug Therapy, Combination; Humans; Lithium; Lithium Carbonate; Valproic Acid | 1989 |
Phenomenology of rapid cycling manic depression and its treatment with valproate.
Topics: Bipolar Disorder; Carbamazepine; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Lithium; Male; Valproic Acid | 1989 |
Drug treatment of bipolar depression and mania.
Topics: Antidepressive Agents; Antipsychotic Agents; Bipolar Disorder; Bromocriptine; Carbamazepine; Cholinesterase Inhibitors; Clonidine; Depressive Disorder; Double-Blind Method; Drug Therapy, Combination; Humans; Lithium; Monoamine Oxidase Inhibitors; Phosphatidylcholines; Tryptophan; Valproic Acid; Verapamil | 1985 |
Antidepressant drug therapy for bulimia: current status.
Topics: Antidepressive Agents; Bupropion; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Feeding and Eating Disorders; Fenfluramine; Humans; Hyperphagia; Lithium; Lithium Carbonate; Methamphetamine; Monoamine Oxidase Inhibitors; Nomifensine; Phenytoin; Placebos; Propiophenones; Valproic Acid | 1986 |
Carbamazepine drug interactions.
Topics: Carbamazepine; Cimetidine; Dextropropoxyphene; Drug Interactions; Erythromycin; Humans; Isoniazid; Lithium; Phenobarbital; Phenytoin; Primidone; Protein Binding; Troleandomycin; Valproic Acid; Warfarin | 1986 |
Current perspectives in the pharmacopsychiatry of depression and mania.
Topics: Affective Disorders, Psychotic; Antidepressive Agents; Bipolar Disorder; Depressive Disorder; Endorphins; Humans; Lithium; Narcotics; Receptors, Cell Surface; Receptors, GABA-A; Valproic Acid | 1983 |
Drug exposure during pregnancy: some epidemiologic considerations.
Topics: Abnormalities, Drug-Induced; Benzodiazepines; Caffeine; Dicyclomine; Doxylamine; Drug Combinations; Epidemiologic Methods; Female; Humans; Hydantoins; Immunosuppressive Agents; Lithium; Lithium Carbonate; Phenothiazines; Pregnancy; Pyridoxine; Registries; Risk; Rubella Vaccine; Solvents; Spermatocidal Agents; Trimethadione; Valproic Acid | 1983 |
An update on the diagnosis and treatment of mania in bipolar disorder.
Topics: Bipolar Disorder; Carbamazepine; Diagnosis, Differential; Humans; Lithium; Psychotherapy; Valproic Acid | 1995 |
Treatment of mania in the medically ill.
Topics: Bipolar Disorder; Carbamazepine; Comorbidity; Humans; Lithium; Metabolic Clearance Rate; Neurocognitive Disorders; Patient Care Team; Psychophysiologic Disorders; Psychotropic Drugs; Valproic Acid | 1994 |
A medication algorithm for treatment of bipolar rapid cycling?
Topics: Algorithms; Bipolar Disorder; Carbamazepine; Clozapine; Controlled Clinical Trials as Topic; Drug Administration Schedule; Drug Therapy, Combination; Electroconvulsive Therapy; Humans; Lithium; Treatment Outcome; Valproic Acid | 1995 |
The relationship between substance abuse and bipolar disorder.
Topics: Alcoholism; Bipolar Disorder; Carbamazepine; Comorbidity; Diagnosis, Dual (Psychiatry); Hospitalization; Humans; Lithium; Prevalence; Substance-Related Disorders; Treatment Outcome; Valproic Acid | 1995 |
Predictors of response to divalproex and lithium.
Topics: Bipolar Disorder; Carbamazepine; Comorbidity; Drug Administration Schedule; Drug Therapy, Combination; Humans; Lithium; Probability; Substance-Related Disorders; Treatment Outcome; Valproic Acid | 1995 |
Secondary mania: diagnosis and treatment.
Topics: Age of Onset; Bipolar Disorder; Diagnosis, Differential; Humans; Lithium; Treatment Outcome; Valproic Acid | 1995 |
Mixed or dysphoric manic states: psychopathology and treatment.
Topics: Bipolar Disorder; Diagnosis, Differential; Electroconvulsive Therapy; Humans; Lithium; Psychiatric Status Rating Scales; Risk Factors; Terminology as Topic; Treatment Outcome; Valproic Acid | 1995 |
Treatment approaches for acute mania.
Topics: Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Carbamazepine; Dyskinesia, Drug-Induced; Female; Humans; Lithium; Male; Psychotropic Drugs; Valproic Acid | 1993 |
Practice guideline for the treatment of patients with bipolar disorder. American Psychiatric Association.
Topics: Adolescent; Adult; Antidepressive Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Carbamazepine; Child; Combined Modality Therapy; Electroconvulsive Therapy; Female; Humans; Lithium; Male; Psychotherapy; Valproic Acid | 1994 |
Valproate in bipolar disorder: the Canadian perspective.
Topics: Anticonvulsants; Antipsychotic Agents; Bipolar Disorder; Drug Therapy, Combination; Humans; Lithium; Valproic Acid | 1993 |
Mania and Down's syndrome.
Topics: Adult; Antipsychotic Agents; Bipolar Disorder; Down Syndrome; Humans; Lithium; Male; Middle Aged; Valproic Acid | 1993 |
[Drug combinations of lithium: reasons and limitations].
Topics: Antidepressive Agents; Bipolar Disorder; Carbamazepine; Drug Therapy, Combination; Female; Humans; Lithium; Male; Valproic Acid | 1993 |
Rapid cycling bipolar disorder and its treatment with valproate.
Topics: Adult; Bipolar Disorder; Female; Humans; Lithium; Male; Psychiatric Status Rating Scales; Valproic Acid | 1993 |
Lithium therapy: limitations and alternatives in the treatment of bipolar disorders.
Topics: Anticonvulsants; Bipolar Disorder; Carbamazepine; Humans; Lithium; Patient Compliance; Tranquilizing Agents; Treatment Outcome; Valproic Acid | 1995 |
Outcome in the pharmacologic treatment of bipolar disorder.
Topics: Antimanic Agents; Bipolar Disorder; Carbamazepine; Clinical Trials as Topic; Follow-Up Studies; Humans; Lithium; Psychotropic Drugs; Treatment Outcome; Valproic Acid | 1996 |
Predictors of response to mood stabilizers.
Topics: Antimanic Agents; Bipolar Disorder; Carbamazepine; Clinical Trials as Topic; Comorbidity; Humans; Lithium; Treatment Outcome; Valproic Acid | 1996 |
Role of newer medications for bipolar disorder.
Topics: Antidepressive Agents; Antimanic Agents; Bipolar Disorder; Carbamazepine; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Lithium; Long-Term Care; Psychotropic Drugs; Treatment Outcome; Valproic Acid | 1996 |
The diagnosis and treatment of mania in the elderly.
Topics: Age of Onset; Aged; Anticonvulsants; Bipolar Disorder; Carbamazepine; Diagnosis, Differential; Dose-Response Relationship, Drug; Humans; Lithium; Middle Aged; Schizophrenia; Tranquilizing Agents; Valproic Acid | 1996 |
Lithium compared to valproic acid and carbamazepine in the treatment of mania: a statistical meta-analysis.
Topics: Bipolar Disorder; Carbamazepine; Humans; Lithium; Valproic Acid | 1996 |
A speculative model of affective illness cyclicity based on patterns of drug tolerance observed in amygdala-kindled seizures.
Topics: Affect; Amygdala; Animals; Anticonvulsants; Bipolar Disorder; Carbamazepine; Disease Progression; Drug Administration Schedule; Drug Evaluation, Preclinical; Drug Tolerance; Humans; Kindling, Neurologic; Lithium; Mood Disorders; Neurotransmitter Agents; Periodicity; Rats; Seizures; Valproic Acid | 1996 |
Alopecia and mood stabilizer therapy.
Topics: Adult; Alopecia; Antimanic Agents; Bipolar Disorder; Case Management; Diethylcarbamazine; Female; Humans; Incidence; Lithium; Time Factors; Valproic Acid | 1996 |
Dosing strategies and time course of response to antimanic drugs.
Topics: Bipolar Disorder; Carbamazepine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Humans; Lithium; Randomized Controlled Trials as Topic; Treatment Outcome; Valproic Acid | 1996 |
Health-economic implications of the onset of action of antimanic agents.
Topics: Bipolar Disorder; Carbamazepine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Costs; Health Care Costs; Humans; Lithium; Randomized Controlled Trials as Topic; Treatment Outcome; Valproic Acid | 1996 |
Regulation of signal transduction pathways by mood-stabilizing agents: implications for the delayed onset of therapeutic efficacy.
Topics: Adenylyl Cyclases; Animals; Bipolar Disorder; Carbamazepine; Cell Line; Glioma; GTP-Binding Proteins; Humans; Lithium; Luciferases; Protein Kinase C; Rats; Receptors, Neurotransmitter; Signal Transduction; Valproic Acid | 1996 |
G protein-mediated signal transduction as a target of antidepressant and antibipolar drug action: evidence from model systems.
Topics: Adenylyl Cyclases; Antidepressive Agents; Desipramine; Down-Regulation; GTP-Binding Proteins; Humans; Lithium; Receptors, Adrenergic, beta; Receptors, Neurotransmitter; Signal Transduction; Valproic Acid | 1996 |
Polypharmacy in bipolar I disorder.
Topics: Bipolar Disorder; Carbamazepine; Humans; Lithium; Valproic Acid | 1996 |
Mood stabilizer combinations: a review of safety and efficacy.
Topics: Acetates; Amines; Anticonvulsants; Antipsychotic Agents; Bipolar Disorder; Calcium Channel Blockers; Clinical Trials as Topic; Clozapine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Lithium; Risperidone; Valproic Acid | 1998 |
Drug treatment of mania: a critical review.
Topics: Anti-Anxiety Agents; Anticonvulsants; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Calcium Channel Blockers; Carbamazepine; Decision Making; Electroconvulsive Therapy; Humans; Lithium; Randomized Controlled Trials as Topic; Treatment Outcome; Valproic Acid | 1998 |
Key treatment studies of lithium in manic-depressive illness: efficacy and side effects.
Topics: Acute Disease; Bipolar Disorder; Clinical Trials as Topic; Delayed-Action Preparations; Drug Administration Schedule; Drug Therapy, Combination; Humans; Lithium; Placebos; Randomized Controlled Trials as Topic; Treatment Outcome; Valproic Acid | 1998 |
Special considerations: use of lithium in children, adolescents, and elderly populations.
Topics: Abnormalities, Drug-Induced; Acetates; Adolescent; Adult; Age Factors; Aged; Amines; Anticonvulsants; Bipolar Disorder; Carbamazepine; Child; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Lithium; Male; Pregnancy; Triazines; Valproic Acid | 1998 |
[Current trends in the therapeutic use of thymic regulators].
Topics: Anticonvulsants; Antidepressive Agents; Depressive Disorder; Female; Humans; Lithium; Mood Disorders; Pregnancy; Pregnancy Complications; Valproic Acid | 1998 |
Modulation of CNS signal transduction pathways and gene expression by mood-stabilizing agents: therapeutic implications.
Topics: Bipolar Disorder; Calcium-Calmodulin-Dependent Protein Kinases; Carbamazepine; Gene Expression; Glycogen Synthase Kinases; Humans; Lithium; Mood Disorders; Protein Kinase C; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Tamoxifen; Transcription Factor AP-1; Valproic Acid | 1999 |
Anticonvulsant therapy and suicide risk in affective disorders.
Topics: Amitriptyline; Anticonvulsants; Bipolar Disorder; Carbamazepine; Double-Blind Method; Female; Follow-Up Studies; Humans; Lamotrigine; Lithium; Male; Mood Disorders; Prospective Studies; Risk Factors; Suicide; Suicide Prevention; Triazines; Valproic Acid | 1999 |
Use of psychotropic medications in breast-feeding women: acute and prophylactic treatment.
Topics: Antidepressive Agents, Tricyclic; Benzodiazepines; Breast Feeding; Carbamazepine; Depression, Postpartum; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Lithium; Mental Disorders; Psychotropic Drugs; Puerperal Disorders; Risk Assessment; Secondary Prevention; Selective Serotonin Reuptake Inhibitors; Valproic Acid | 1998 |
Management of acute mania.
Topics: Acute Disease; Algorithms; Anticonvulsants; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Carbamazepine; Clinical Trials as Topic; Humans; Lithium; Olanzapine; Pirenzepine; Research Design; Risk Factors; Treatment Outcome; Treatment Refusal; Valproic Acid | 1999 |
Mood-stabilizing drugs in depression.
Topics: Acute Disease; Anticonvulsants; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Bipolar Disorder; Carbamazepine; Clinical Trials as Topic; Depressive Disorder; Drug Therapy, Combination; Humans; Lithium; Secondary Prevention; Treatment Outcome; Valproic Acid | 1999 |
Metabolism and excretion of mood stabilizers and new anticonvulsants.
Topics: Anticonvulsants; Antimanic Agents; Carbamazepine; Drug Interactions; Drug Therapy, Combination; Humans; Lithium; Mood Disorders; Valproic Acid | 1999 |
Phenomenology and treatment of agitation.
Topics: Adolescent; Adult; Aged; Akathisia, Drug-Induced; Antipsychotic Agents; Anxiety Disorders; Benzodiazepines; Clinical Trials as Topic; Comorbidity; Depressive Disorder; Diagnosis, Differential; Female; Humans; Lithium; Middle Aged; Prevalence; Psychomotor Agitation; Selective Serotonin Reuptake Inhibitors; Valproic Acid | 1999 |
Treatment of aggression in patients with bipolar disorder.
Topics: Aggression; Antipsychotic Agents; Bipolar Disorder; Carbamazepine; Combined Modality Therapy; Drug Therapy, Combination; Humans; Lithium; Valproic Acid | 1999 |
Rapid cycling bipolar affective disorder in people with intellectual disability: a systematic review.
Topics: Antimanic Agents; Bipolar Disorder; Carbamazepine; Down Syndrome; Humans; Intellectual Disability; Lithium; Treatment Outcome; Valproic Acid | 1999 |
Ziskind-Somerfeld Research Award. Protein kinase C signaling in the brain: molecular transduction of mood stabilization in the treatment of manic-depressive illness.
Topics: Animals; Antimanic Agents; Awards and Prizes; Binding, Competitive; Bipolar Disorder; Blotting, Western; Brain; Calcium-Calmodulin-Dependent Protein Kinases; Disease Models, Animal; Enzyme Activators; Glycogen Synthase Kinase 3; Humans; Lithium; Male; Protein Kinase C; Rats; Rats, Sprague-Dawley; Research; Signal Transduction; Transcription Factor AP-1; Transcription, Genetic; Valproic Acid | 1999 |
[Risk of inducing resistance upon stopping and restarting lithium after long-term usage].
Topics: Adult; Aged; Antidepressive Agents; Antimanic Agents; Bipolar Disorder; Carbamazepine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Drug Tolerance; Humans; Lithium; Male; Middle Aged; Monoamine Oxidase Inhibitors; Treatment Outcome; Valproic Acid | 2000 |
Mood stabilizers during breastfeeding: a review.
Topics: Acetates; Amines; Anticonvulsants; Bipolar Disorder; Breast Feeding; Carbamazepine; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant; Infant, Newborn; Lamotrigine; Lithium; MEDLINE; Milk, Human; Pregnancy; Pregnancy Complications; Puerperal Disorders; Triazines; Valproic Acid | 2000 |
Antidepressant treatment of posttraumatic stress disorder.
Topics: Anticonvulsants; Antidepressive Agents; Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Double-Blind Method; Humans; Lamotrigine; Lithium; Monoamine Oxidase Inhibitors; Placebos; Selective Serotonin Reuptake Inhibitors; Sertraline; Stress Disorders, Post-Traumatic; Treatment Outcome; Triazines; Valproic Acid | 2000 |
Hair loss in psychopharmacology.
Topics: Adolescent; Adult; Alopecia; Antidepressive Agents; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Carbamazepine; Dose-Response Relationship, Drug; Female; Humans; Lithium; Male; Selective Serotonin Reuptake Inhibitors; Valproic Acid | 2000 |
The psychopharmacologic specificity of the lithium ion: origins and trajectory.
Topics: Anticonvulsants; Australia; Bipolar Disorder; Carbamazepine; Drug Therapy, Combination; History, 20th Century; Humans; Lithium; Mental Disorders; Psychopharmacology; United States; Valproic Acid | 2000 |
Management of bipolar disorder.
Topics: Adolescent; Adult; Age Distribution; Antimanic Agents; Bipolar Disorder; Carbamazepine; Child, Preschool; Female; Humans; Incidence; Lithium; Male; Monitoring, Physiologic; Pregnancy; Prognosis; Recurrence; Risk Assessment; Treatment Outcome; Valproic Acid | 2000 |
An ever-increasing pharmacopoeia for the management of patients with bipolar disorder.
Topics: Acetates; Amines; Anticonvulsants; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Carbamazepine; Clozapine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Electroconvulsive Therapy; Electromagnetic Phenomena; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Lithium; Olanzapine; Pirenzepine; Risperidone; Topiramate; Treatment Outcome; Triazines; Valproic Acid | 2000 |
The nature of bipolar disorder.
Topics: Bipolar Disorder; Cell Death; Circadian Rhythm; Corticotropin-Releasing Hormone; Disease Models, Animal; Dopamine; GTP-Binding Proteins; Humans; Lithium; Neurotransmitter Agents; Norepinephrine; Phosphatidylinositols; Protein Kinase C; Serotonin; Signal Transduction; Valproic Acid | 2000 |
New treatments for bipolar disorder: the role of atypical neuroleptic agents.
Topics: Acute Disease; Algorithms; Anticonvulsants; Antidepressive Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Clozapine; Dibenzothiazepines; Drug Therapy, Combination; Humans; Lithium; Olanzapine; Pirenzepine; Psychotic Disorders; Quetiapine Fumarate; Risperidone; Treatment Outcome; Valproic Acid | 2000 |
Effects of antimanic mood-stabilizing drugs on fetuses, neonates, and nursing infants.
Topics: Abnormalities, Drug-Induced; Acetates; Adult; Amines; Antimanic Agents; Benzodiazepines; Breast Feeding; Carbamazepine; Cyclohexanecarboxylic Acids; Female; Fetus; Gabapentin; gamma-Aminobutyric Acid; Haloperidol; Humans; Infant, Newborn; Lithium; Mood Disorders; Olanzapine; Pirenzepine; Placenta; Pregnancy; Risk Factors; Valproic Acid | 2001 |
Special issues in the treatment of paediatric bipolar disorder.
Topics: Anticonvulsants; Antipsychotic Agents; Bipolar Disorder; Carbamazepine; Child; Humans; Lithium; Valproic Acid | 2001 |
Bipolar rapid cycling: focus on depression as its hallmark.
Topics: Anticonvulsants; Antidepressive Agents, Tricyclic; Bipolar Disorder; Comorbidity; Controlled Clinical Trials as Topic; Depressive Disorder; Drug Therapy, Combination; Humans; Lamotrigine; Lithium; Patient Compliance; Placebos; Substance-Related Disorders; Survival Analysis; Treatment Outcome; Triazines; Valproic Acid | 2001 |
The effects of lithium, valproic acid, and carbamazepine during pregnancy and lactation.
Topics: Adult; Anticonvulsants; Antimanic Agents; Carbamazepine; Female; Humans; Lactation; Lithium; Pregnancy; Pregnancy Complications; Valproic Acid | 2001 |
[Prophylactic long-term therapy of affective disorders with lithium, valproic acid and carbamazepine--effectiveness and cost-effectiveness].
Topics: Antimanic Agents; Carbamazepine; Cost-Benefit Analysis; Disease Management; Germany; Humans; Lithium; Mood Disorders; Randomized Controlled Trials as Topic; Retrospective Studies; Valproic Acid | 2001 |
Valproic acid, valproate and divalproex in the maintenance treatment of bipolar disorder.
Topics: Antimanic Agents; Bipolar Disorder; Humans; Lithium; Randomized Controlled Trials as Topic; Valproic Acid | 2001 |
Developments in mood stabilisers.
Topics: Anticonvulsants; Antidepressive Agents; Antipsychotic Agents; Bipolar Disorder; Carbamazepine; Electroconvulsive Therapy; Electromagnetic Fields; Fructose; Humans; Lamotrigine; Lithium; Nipecotic Acids; Psychotherapy; Suicide Prevention; Thyroxine; Tiagabine; Topiramate; Triazines; Valproic Acid | 2001 |
Stabilization of mood from below versus above baseline in bipolar disorder: a new nomenclature.
Topics: Affect; Antidepressive Agents; Antipsychotic Agents; Bipolar Disorder; Carbamazepine; Clinical Trials as Topic; Double-Blind Method; Electroconvulsive Therapy; Humans; Lamotrigine; Lithium; Models, Psychological; Terminology as Topic; Treatment Outcome; Triazines; Valproic Acid | 2002 |
Predictors of treatment response in bipolar disorders: evidence from clinical and brain imaging studies.
Topics: Anticonvulsants; Antimanic Agents; Bipolar Disorder; Brain; Carbamazepine; gamma-Aminobutyric Acid; Humans; Lithium; Magnetic Resonance Imaging; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon; Valproic Acid | 2002 |
The evolving role of topiramate among other mood stabilizers in the management of bipolar disorder.
Topics: Acetates; Acute Disease; Amines; Anticonvulsants; Antimanic Agents; Bipolar Disorder; Carbamazepine; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Lithium; Randomized Controlled Trials as Topic; Topiramate; Triazines; Valproic Acid | 2001 |
Do lithium and anticonvulsants target the brain arachidonic acid cascade in bipolar disorder?
Topics: Animals; Anticonvulsants; Antimanic Agents; Arachidonic Acid; Bipolar Disorder; Brain; Brain Chemistry; Cyclooxygenase 2; Docosahexaenoic Acids; Humans; Isoenzymes; Lithium; Membrane Proteins; Models, Animal; Palmitic Acid; Phospholipids; Prostaglandin-Endoperoxide Synthases; Prostaglandins E; Rats; Valproic Acid | 2002 |
Synaptic, intracellular, and neuroprotective mechanisms of anticonvulsants: are they relevant for the treatment and course of bipolar disorders?
Topics: Anticonvulsants; Bipolar Disorder; Carbamazepine; gamma-Aminobutyric Acid; Gene Expression Regulation; Glutamic Acid; Humans; Lithium; Signal Transduction; Synaptic Transmission; Valproic Acid | 2002 |
The Wnt signaling pathway in bipolar disorder.
Topics: Animals; Antimanic Agents; Bipolar Disorder; Circadian Rhythm; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Lithium; Neuroprotective Agents; Proto-Oncogene Proteins; Signal Transduction; Valproic Acid; Wnt Proteins; Zebrafish Proteins | 2002 |
Carbamazepine and valproate in the maintenance treatment of bipolar disorder.
Topics: Anticonvulsants; Bipolar Disorder; Carbamazepine; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Humans; Lithium; Placebos; Randomized Controlled Trials as Topic; Secondary Prevention; Survival Analysis; Treatment Outcome; Valproic Acid | 2002 |
Lithium and valproic acid: parallels and contrasts in diverse signaling contexts.
Topics: Animals; Antimanic Agents; Bipolar Disorder; Gene Expression; Glycogen Synthase Kinase 3; Histone Deacetylases; Humans; Lithium; Mitogen-Activated Protein Kinases; Neurons; Neuroprotective Agents; Neurotransmitter Agents; Phenotype; Phosphoric Monoester Hydrolases; Reproduction; Signal Transduction; Sodium Channels; Valproic Acid | 2002 |
Myo-inositol-1-phosphate (MIP) synthase: a possible new target for antibipolar drugs.
Topics: Animals; Antipsychotic Agents; Bipolar Disorder; Blood Cells; Enzyme Inhibitors; Eukaryotic Cells; Humans; Inositol; Lithium; Models, Biological; Phosphoric Monoester Hydrolases; Prefrontal Cortex; Saccharomyces cerevisiae; Valproic Acid | 2002 |
New approaches in managing bipolar depression.
Topics: Anticonvulsants; Antidepressive Agents; Antipsychotic Agents; Bipolar Disorder; Carbamazepine; Clinical Trials as Topic; Drug Administration Schedule; Drug Therapy, Combination; Humans; Lamotrigine; Lithium; Treatment Outcome; Triazines; Valproic Acid | 2003 |
Antidepressant properties of anticonvulsant drugs for bipolar disorder.
Topics: Acetates; Affect; Amines; Anticonvulsants; Antidepressive Agents; Bipolar Disorder; Carbamazepine; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Lithium; Topiramate; Triazines; Valproic Acid | 2003 |
The use of mood stabilizers as plasticity enhancers in the treatment of neuropsychiatric disorders.
Topics: Anticonvulsants; Apoptosis; Atrophy; Brain; Central Nervous System Diseases; Gene Expression; Genes, bcl-2; Humans; Lithium; Mental Disorders; Mood Disorders; Neuronal Plasticity; Neurons; Signal Transduction; Valproic Acid | 2003 |
Drug interactions of lithium and other antimanic/mood-stabilizing medications.
Topics: Anticonvulsants; Antimanic Agents; Bipolar Disorder; Carbamazepine; Drug Interactions; Humans; Lithium; Valproic Acid | 2003 |
Search for a common mechanism of mood stabilizers.
Topics: Affect; Animals; Anticonvulsants; Antimanic Agents; Carbamazepine; Glycogen Synthase Kinase 3; Humans; Inositol; Lithium; Mood Disorders; Signal Transduction; Valproic Acid | 2003 |
[Manic phase (manic episode)].
Topics: Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Diagnostic and Statistical Manual of Mental Disorders; Electroconvulsive Therapy; Humans; Lithium; Olanzapine; Pirenzepine; Psychotherapy; Reference Standards; Valproic Acid | 2003 |
[Mechanism and clinical effects of drugs for mood disorder].
Topics: Antidepressive Agents; Antimanic Agents; Biogenic Monoamines; Humans; Inositol; Lithium; Meta-Analysis as Topic; Mood Disorders; Secondary Prevention; Synapses; Treatment Outcome; Valproic Acid | 2003 |
[Pharmacokinetics and drug interaction of antidepressants and anti-manic drugs].
Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents; Antimanic Agents; Carbamazepine; Cyclopropanes; Cytochrome P-450 Enzyme System; Drug Interactions; Fluvoxamine; Humans; Isoenzymes; Lithium; Milnacipran; Paroxetine; Selective Serotonin Reuptake Inhibitors; Valproic Acid | 2003 |
[Antidepressant induced rapid cycling].
Topics: Antidepressive Agents, Tricyclic; Antimanic Agents; Bipolar Disorder; Drug Therapy, Combination; Humans; Lithium; Risk Factors; Selective Serotonin Reuptake Inhibitors; Thyroxine; Valproic Acid | 2003 |
The safety and early efficacy of oral-loaded divalproex versus standard-titration divalproex, lithium, olanzapine, and placebo in the treatment of acute mania associated with bipolar disorder.
Topics: Acute Disease; Adolescent; Adult; Aged; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Diagnostic and Statistical Manual of Mental Disorders; Double-Blind Method; Drug Tolerance; Female; Humans; Lithium; Male; Middle Aged; Olanzapine; Pirenzepine; Randomized Controlled Trials as Topic; Severity of Illness Index; Titrimetry; Treatment Outcome; Valproic Acid | 2003 |
[Treatment of acute bipolar disorder. Intriguing balancing act between mania and depression].
Topics: Acute Disease; Algorithms; Antidepressive Agents; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Carbamazepine; Drug Therapy, Combination; Humans; Isotopes; Lamotrigine; Lithium; Olanzapine; Pirenzepine; Risperidone; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Triazines; Valproic Acid | 2003 |
[Persisting deficits after severe depression].
Topics: Adult; Antidepressive Agents; Antimanic Agents; Antipsychotic Agents; Carbamazepine; Cognition Disorders; Depression; Female; Follow-Up Studies; Humans; Isotopes; Lithium; Male; Middle Aged; Neuropsychological Tests; Time Factors; Tranquilizing Agents; Valproic Acid | 2003 |
Possible involvement of the ERK signaling cascade in bipolar disorder: behavioral leads from the study of mutant mice.
Topics: Animals; Behavior, Animal; Bipolar Disorder; Humans; Lithium; Mice; Mice, Mutant Strains; Mitogen-Activated Protein Kinases; Signal Transduction; Valproic Acid | 2003 |
Regulation of cellular plasticity cascades in the pathophysiology and treatment of mood disorders: role of the glutamatergic system.
Topics: Animals; Antidepressive Agents; Antimanic Agents; Glucocorticoids; Glutamates; Humans; Lithium; Mood Disorders; Neuronal Plasticity; Neurons; Receptors, AMPA; Signal Transduction; Stress, Psychological; Valproic Acid | 2003 |
Special considerations in treating bipolar disorder in women.
Topics: Anticonvulsants; Antimanic Agents; Bipolar Disorder; Breast Feeding; Contraceptives, Oral; Drug Interactions; Female; Humans; Lithium; Menopause; Menstrual Cycle; Postpartum Period; Practice Guidelines as Topic; Pregnancy; Sex Factors; Valproic Acid; Women's Health | 2004 |
A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder.
Topics: Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Cost-Benefit Analysis; Dibenzothiazepines; Humans; Lithium; Olanzapine; Quetiapine Fumarate; Randomized Controlled Trials as Topic; Valproic Acid | 2004 |
An overview of primary care assessment and management of bipolar disorder.
Topics: Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Diagnostic Errors; Humans; Lamotrigine; Lithium; Olanzapine; Primary Health Care; Triazines; Valproic Acid | 2004 |
Strategies for preventing the recurrence of bipolar disorder.
Topics: Anticonvulsants; Antidepressive Agents; Benzodiazepines; Bipolar Disorder; Cognitive Behavioral Therapy; Combined Modality Therapy; Drug Therapy, Combination; Humans; Lamotrigine; Lithium; Olanzapine; Patient Education as Topic; Psychotherapy; Secondary Prevention; Selective Serotonin Reuptake Inhibitors; Triazines; Valproic Acid | 2004 |
Pharmacologic management of behavioral instability in medically ill pediatric patients.
Topics: Adolescent; Adrenergic alpha-Agonists; Aggression; Analgesics, Non-Narcotic; Behavior Therapy; Behavioral Medicine; Benzodiazepines; Carbamazepine; Central Nervous System Stimulants; Child; Clonidine; Diphenhydramine; Histamine H1 Antagonists; Humans; Lithium; Methylphenidate; Psychomotor Agitation; Valproic Acid | 2004 |
Bipolar depression: an overview.
Topics: Acute Disease; Antidepressive Agents; Antimanic Agents; Benzodiazepines; Bipolar Disorder; Chemoprevention; Contraindications; Depressive Disorder; Diagnosis, Differential; Drug Therapy, Combination; Humans; Lamotrigine; Lithium; Olanzapine; Triazines; Valproic Acid | 2004 |
Employing pharmacologic treatment of bipolar disorder to greatest effect.
Topics: Anticonvulsants; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Lamotrigine; Lithium; Olanzapine; Receptors, GABA; Receptors, Glutamate; Treatment Outcome; Triazines; Valproic Acid | 2004 |
Bipolar disorder.
Topics: Antidepressive Agents; Antimanic Agents; Bipolar Disorder; Chlorpromazine; Humans; Lithium; Psychotherapy; Valproic Acid | 2003 |
Recognizing and managing bipolar disorder in children.
Topics: Adolescent; Age Factors; Amphetamine; Anticonvulsants; Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Bipolar Disorder; Child; Child, Preschool; Comorbidity; Humans; Lithium; Mental Disorders; Treatment Outcome; Valproic Acid | 2005 |
Latest therapies for bipolar disorder. Looking beyond lithium.
Topics: Anticonvulsants; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Carbamazepine; Drug Therapy, Combination; Humans; Lithium; Valproic Acid | 2005 |
Atypical antipsychotic augmentation of mood stabilizer therapy in bipolar disorder.
Topics: Acute Disease; Anticonvulsants; Antipsychotic Agents; Bipolar Disorder; Clinical Trials as Topic; Depressive Disorder; Drug Therapy, Combination; Humans; Lithium; Treatment Outcome; Valproic Acid; Weight Gain | 2005 |
Glycogen synthase kinase-3: a putative molecular target for lithium mimetic drugs.
Topics: Animals; Antidepressive Agents; Antipsychotic Agents; Circadian Rhythm; Disease Models, Animal; Electroconvulsive Therapy; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Humans; Lithium; Models, Biological; Mood Disorders; Neurotransmitter Agents; Signal Transduction; Valproic Acid | 2005 |
[Are mood stabilizers beneficial in the treatment of schizophrenia?].
Topics: Antimanic Agents; Antipsychotic Agents; Carbamazepine; Drug Interactions; Drug Therapy, Combination; Humans; Lithium; Schizophrenia; Valproic Acid | 2005 |
The antiapoptotic actions of mood stabilizers: molecular mechanisms and therapeutic potentials.
Topics: Affect; Animals; Antimanic Agents; Apoptosis; Excitatory Amino Acid Agonists; Humans; Lithium; N-Methylaspartate; Rats; Stroke; Valproic Acid | 2005 |
Management options for bipolar disorder in children and adolescents.
Topics: Adolescent; Benzodiazepines; Bipolar Disorder; Carbamazepine; Child; Clozapine; Dibenzothiazepines; Humans; Lithium; Olanzapine; Quetiapine Fumarate; Risperidone; Valproic Acid | 2005 |
Cellular plasticity cascades: genes-to-behavior pathways in animal models of bipolar disorder.
Topics: Animals; Antimanic Agents; Behavior, Animal; Bipolar Disorder; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Glycogen Synthase Kinases; Lithium; Mice; Neuronal Plasticity; Protein Kinase C; Proto-Oncogene Proteins c-bcl-2; Receptors, Glucocorticoid; Receptors, Glutamate; Signal Transduction; Valproic Acid | 2006 |
Cellular plasticity cascades: targets for the development of novel therapeutics for bipolar disorder.
Topics: Antimanic Agents; Bipolar Disorder; Glycogen Synthase Kinase 3; Histone Deacetylases; Humans; Lithium; Neuronal Plasticity; Valproic Acid | 2006 |
A systematic review and economic model of the clinical effectiveness and cost-effectiveness of interventions for preventing relapse in people with bipolar disorder.
Topics: Adult; Antidepressive Agents; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Carbamazepine; Cognitive Behavioral Therapy; Cost-Benefit Analysis; Databases, Bibliographic; Female; Humans; Lamotrigine; Lithium; Male; Models, Economic; Olanzapine; Outcome and Process Assessment, Health Care; Randomized Controlled Trials as Topic; Secondary Prevention; Triazines; Valproic Acid | 2007 |
Mode of action of mood stabilizers: is the arachidonic acid cascade a common target?
Topics: Antimanic Agents; Arachidonic Acid; Bipolar Disorder; Brain; Carbamazepine; Humans; Lithium; Valproic Acid | 2008 |
Dialysis in the poisoned patient.
Topics: Analgesics; Ethylene Glycol; Female; Humans; Lithium; Methanol; Middle Aged; Poisoning; Renal Dialysis; Valproic Acid | 2010 |
A meta-analysis of mood stabilizers for Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Antimanic Agents; Carbamazepine; Female; Humans; Lithium; Male; Middle Aged; Randomized Controlled Trials as Topic; Valproic Acid | 2010 |
Comparative efficacy and acceptability of mood stabilizer and second generation antipsychotic monotherapy for acute mania--a systematic review and meta-analysis.
Topics: Affect; Antidepressive Agents; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Double-Blind Method; Humans; Lithium; Lithium Carbonate; Lithium Compounds; Mood Disorders; Olanzapine; Randomized Controlled Trials as Topic; Valproic Acid | 2011 |
[Mood stabilizers].
Topics: Antimanic Agents; Bipolar Disorder; Carbamazepine; Humans; Lamotrigine; Lithium; Triazines; Valproic Acid | 2012 |
The efficacy and safety of switching to ziprasidone from olanzapine in patients with bipolar I disorder: an 8-week, multicenter, open-label study.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Drug Substitution; Drug Therapy, Combination; Dyslipidemias; Female; Humans; Lithium; Male; Middle Aged; Olanzapine; Piperazines; Prospective Studies; Thiazoles; Treatment Outcome; Valproic Acid; Young Adult | 2013 |
Can the response to mood stabilizers be predicted in bipolar disorder?
Topics: Antimanic Agents; Bipolar Disorder; Circadian Rhythm Signaling Peptides and Proteins; Genetic Association Studies; Genome-Wide Association Study; Humans; Inositol; Lithium; Neurotransmitter Agents; Pharmacogenetics; Phenotype; Valproic Acid | 2014 |
The effectiveness of lurasidone as an adjunct to lithium or divalproex in the treatment of bipolar disorder.
Topics: Antimanic Agents; Bipolar Disorder; Drug Therapy, Combination; Humans; Isoindoles; Lithium; Lurasidone Hydrochloride; Thiazoles; Treatment Outcome; Valproic Acid | 2014 |
[Adverse events of psychotropic drugs].
Topics: Animals; Anticonvulsants; Humans; Japan; Lithium; Mental Disorders; Psychotropic Drugs; Quality of Life; Valproic Acid | 2014 |
Degradation of misfolded proteins by autophagy: is it a strategy for Huntington's disease treatment?
Topics: Autophagy; Carbamazepine; Humans; Huntingtin Protein; Huntington Disease; Lithium; Mutant Proteins; Nerve Tissue Proteins; Oxazoles; Peptides; Rilmenidine; Sirolimus; Trehalose; Trinucleotide Repeat Expansion; Valproic Acid | 2013 |
Is the Modulation of Autophagy the Future in the Treatment of Neurodegenerative Diseases?
Topics: Animals; Autophagy; Disease Models, Animal; Food; Humans; Isothiocyanates; Lithium; Neurodegenerative Diseases; Resveratrol; Sirolimus; Spermidine; Stilbenes; Sulfoxides; Trehalose; Valproic Acid | 2015 |
Mood stabilizers during breastfeeding: a systematic review of the recent literature.
Topics: Bipolar Disorder; Breast Feeding; Female; Humans; Infant; Infant Welfare; Lithium; Milk, Human; Postpartum Period; Psychotropic Drugs; Puerperal Disorders; Valproic Acid | 2016 |
The effect of mood-stabilizing drugs on cytokine levels in bipolar disorder: A systematic review.
Topics: Affect; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Cytokines; Female; Humans; Lamotrigine; Lithium; Triazines; Valproic Acid | 2016 |
Symptomatology and predictors of antidepressant efficacy in extended responders to a single ketamine infusion.
Topics: Adult; Alcohol-Related Disorders; Antidepressive Agents; Bipolar Disorder; Depressive Disorder, Major; Female; Humans; Infusions, Intravenous; Ketamine; Lithium; Male; Middle Aged; Psychiatric Status Rating Scales; Treatment Outcome; Valproic Acid | 2017 |
Mining the topography and dynamics of the 4D Nucleome to identify novel CNS drug pathways.
Topics: Brain; Cell Nucleus; Chromosomes, Human; Circadian Rhythm; Computational Biology; Data Mining; Gene Expression Regulation; Genome, Human; Humans; Lithium; Nerve Tissue Proteins; Neurons; Pharmacogenetics; Psychotropic Drugs; Transcription, Genetic; Valproic Acid | 2017 |
Psychotic and Bipolar Disorders: Bipolar Disorder.
Topics: Antimanic Agents; Bipolar Disorder; Cardiovascular Diseases; Chronic Pain; Comorbidity; Family Practice; Humans; Lithium; Metabolic Syndrome; Migraine Disorders; Preventive Medicine; Psychiatry; Referral and Consultation; Stroke; Substance-Related Disorders; Valproic Acid | 2017 |
Is there consensus across international evidence-based guidelines for the psychotropic drug management of bipolar disorder during the perinatal period?
Topics: Anticonvulsants; Antidepressive Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Breast Feeding; Carbamazepine; Consensus; Electroconvulsive Therapy; Evidence-Based Medicine; Female; Humans; Lamotrigine; Lithium; Practice Guidelines as Topic; Pregnancy; Psychotropic Drugs; Retrospective Studies; Triazines; Valproic Acid | 2018 |
Mixed states in bipolar and major depressive disorders: systematic review and quality appraisal of guidelines.
Topics: Antidepressive Agents; Antimanic Agents; Antipsychotic Agents; Aripiprazole; Bipolar Disorder; Depressive Disorder, Major; Diagnostic and Statistical Manual of Mental Disorders; Drug Therapy, Combination; Electroconvulsive Therapy; Humans; Lithium; Lurasidone Hydrochloride; Olanzapine; Paliperidone Palmitate; Piperazines; Practice Guidelines as Topic; Quetiapine Fumarate; Thiazoles; Valproic Acid | 2018 |
Lithium and valproate serum level fluctuations within the menstrual cycle: a systematic review.
Topics: Affect; Bipolar Disorder; Female; Humans; Lithium; Male; Menstrual Cycle; Mood Disorders; Valproic Acid | 2019 |
Important role of mitochondria and the effect of mood stabilizers on mitochondrial function.
Topics: Calcium; Energy Metabolism; Humans; Lithium; Mental Disorders; Mitochondria; Psychotropic Drugs; Reactive Oxygen Species; Signal Transduction; Valproic Acid | 2019 |
Bipolar disorders.
Topics: Adolescent; Adult; Anticonvulsants; Antidepressive Agents; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Carbamazepine; Cardiovascular Diseases; Child; Child Abuse; Comorbidity; Depressive Disorder, Major; Environmental Exposure; Humans; Lamotrigine; Lithium; Mania; Suicide; Suicide Prevention; Valproic Acid; Young Adult | 2020 |
Old Age Bipolar Disorder-Epidemiology, Aetiology and Treatment.
Topics: Aged; Anticonvulsants; Antipsychotic Agents; Bipolar Disorder; Humans; Lithium; Valproic Acid | 2021 |
Pharmacological treatment for bipolar mania: a systematic review and network meta-analysis of double-blind randomized controlled trials.
Topics: Adult; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Bipolar Disorder; Carbamazepine; Female; Haloperidol; Humans; Lithium; Male; Mania; Network Meta-Analysis; Olanzapine; Paliperidone Palmitate; Quetiapine Fumarate; Randomized Controlled Trials as Topic; Risperidone; Tamoxifen; Valproic Acid | 2022 |
A cumulative Bayesian network meta-analysis on the comparative efficacy of pharmacotherapies for mania over the last 40 years.
Topics: Adult; Antimanic Agents; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Carbamazepine; Dibenzocycloheptenes; Haloperidol; Humans; Lithium; Mania; Network Meta-Analysis; Olanzapine; Paliperidone Palmitate; Pharmaceutical Preparations; Piperazines; Quetiapine Fumarate; Risperidone; Tamoxifen; Thiazoles; Valproic Acid | 2022 |
Psychotropic Drugs and Adverse Kidney Effects: A Systematic Review of the Past Decade of Research.
Topics: Aged; Anticonvulsants; Antidepressive Agents; Antipsychotic Agents; Benzodiazepines; Diabetes Insipidus, Nephrogenic; Female; Humans; Kidney; Lithium; Lithium Compounds; Psychotropic Drugs; Renal Insufficiency, Chronic; Valproic Acid | 2022 |
Valproate and lithium: Old drugs for new pharmacological approaches in brain tumors?
Topics: Antimanic Agents; Bipolar Disorder; Brain Neoplasms; Glioblastoma; Humans; Lithium; Lithium Carbonate; Lithium Chloride; Pharmaceutical Preparations; Valproic Acid | 2023 |
[Effects of lithium, valproic acid, carbamazepine and antipsychotic agents on cognition in bipolar disorders-A systematic review].
Topics: Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Carbamazepine; Cognition; Dementia; Humans; Lithium; Valproic Acid | 2023 |
Safety and efficacy of lithium in patients with amyotrophic lateral sclerosis: a systematic review and meta-analysis of randomized controlled trials.
Topics: Amyotrophic Lateral Sclerosis; Humans; Lithium; Randomized Controlled Trials as Topic; Valproic Acid; Vital Capacity | 2023 |
T cells: an emerging cast of roles in bipolar disorder.
Topics: Antimanic Agents; Bipolar Disorder; Humans; Lithium; T-Lymphocytes; Valproic Acid | 2023 |
84 trial(s) available for valproic acid and lithium
| Article | Year |
|---|---|
Dysphoric mania.
Topics: Bipolar Disorder; Double-Blind Method; Humans; Lithium; Psychiatric Status Rating Scales; Valproic Acid | 1992 |
[Comparative effectiveness of preventive use of lithium carbonate, carbamazepine and sodium valproate in affective and schizoaffective psychoses].
Topics: Adult; Affective Disorders, Psychotic; Aged; Carbamazepine; Humans; Lithium; Lithium Carbonate; Middle Aged; Psychotic Disorders; Recurrence; Valproic Acid | 1991 |
Spectrum of efficacy of valproate in 55 patients with rapid-cycling bipolar disorder.
Topics: Adult; Antidepressive Agents; Bipolar Disorder; Carbamazepine; Clinical Trials as Topic; Depressive Disorder; Drug Therapy, Combination; Female; Humans; Lithium; Male; Outcome and Process Assessment, Health Care; Prospective Studies; Valproic Acid | 1990 |
Non-lithium treatment for bipolar disorder.
Topics: Anticonvulsants; Bipolar Disorder; Carbamazepine; Clinical Trials as Topic; Clonazepam; Drug Therapy, Combination; Humans; Lithium; Lithium Carbonate; Valproic Acid | 1990 |
Phenomenology of rapid cycling manic depression and its treatment with valproate.
Topics: Bipolar Disorder; Carbamazepine; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Lithium; Male; Valproic Acid | 1989 |
Long-term use of valproate in primary psychiatric disorders.
Topics: Adult; Bipolar Disorder; Clinical Trials as Topic; Depressive Disorder; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Lithium; Male; Psychiatric Status Rating Scales; Psychotic Disorders; Valproic Acid | 1989 |
Antidepressant drug therapy for bulimia: current status.
Topics: Antidepressive Agents; Bupropion; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Feeding and Eating Disorders; Fenfluramine; Humans; Hyperphagia; Lithium; Lithium Carbonate; Methamphetamine; Monoamine Oxidase Inhibitors; Nomifensine; Phenytoin; Placebos; Propiophenones; Valproic Acid | 1986 |
Selective response to the anticonvulsant carbamazepine in manic-depressive illness: a case study.
Topics: Bipolar Disorder; Carbamazepine; Dose-Response Relationship, Drug; Female; Humans; Lithium; Middle Aged; Phenytoin; Valproic Acid | 1984 |
Effect of sodium valproate on mania. The GABA-hypothesis of affective disorders.
Topics: Adolescent; Adult; Affective Disorders, Psychotic; Alcohol Withdrawal Delirium; Bipolar Disorder; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Female; gamma-Aminobutyric Acid; Humans; Lithium; Male; Middle Aged; Placebos; Propranolol; Valproic Acid | 1980 |
The relationship between antimanic agent for treatment of classic or dysphoric mania and length of hospital stay.
Topics: Adult; Antimanic Agents; Benzodiazepines; Bipolar Disorder; Carbamazepine; Drug Therapy, Combination; Female; Hospitalization; Humans; Length of Stay; Lithium; Male; Middle Aged; Proportional Hazards Models; Retrospective Studies; Survival Analysis; Treatment Outcome; Valproic Acid | 1996 |
Pharmacokinetic interactions and side effects resulting from concomitant administration of lithium and divalproex sodium.
Topics: Adult; Bipolar Disorder; Chromatography, High Pressure Liquid; Cross-Over Studies; Drug Interactions; Drug Therapy, Combination; Headache; Humans; Lithium; Male; Placebos; Spectrophotometry, Atomic; Valproic Acid | 1996 |
Depression during mania. Treatment response to lithium or divalproex.
Topics: Adult; Bipolar Disorder; Double-Blind Method; Female; Humans; Lithium; Male; Patient Dropouts; Placebos; Psychiatric Status Rating Scales; Severity of Illness Index; Treatment Outcome; Valproic Acid | 1997 |
Valproate prophylaxis in a prospective clinical trial of refractory bipolar disorder.
Topics: Adult; Aged; Ambulatory Care; Bipolar Disorder; Carbamazepine; Drug Resistance; Drug Therapy, Combination; Female; Humans; Lithium; Male; Middle Aged; Prospective Studies; Treatment Outcome; Valproic Acid | 1997 |
Effect size of efficacy measures comparing divalproex, lithium and placebo in acute mania.
Topics: Adolescent; Adult; Aged; Antimanic Agents; Bipolar Disorder; Double-Blind Method; Female; Humans; Lithium; Male; Mathematical Computing; Meta-Analysis as Topic; Middle Aged; Treatment Outcome; Valproic Acid | 1997 |
Lamotrigine in rapid-cycling bipolar disorder.
Topics: Adult; Anticonvulsants; Bipolar Disorder; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluoxetine; Humans; Lamotrigine; Lithium; Male; Middle Aged; Prospective Studies; Psychiatric Status Rating Scales; Regression Analysis; Treatment Outcome; Triazines; Valproic Acid | 1997 |
Treatment algorithm use to optimize management of symptomatic patients with a history of mania.
Topics: Adult; Algorithms; Ambulatory Care; Antipsychotic Agents; Bipolar Disorder; Brief Psychiatric Rating Scale; Clinical Protocols; Decision Trees; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Lithium; Male; Prospective Studies; Psychiatric Status Rating Scales; Treatment Outcome; Valproic Acid | 1998 |
Bipolar depression and antidepressant-induced mania: a naturalistic study.
Topics: Adult; Ambulatory Care; Antidepressive Agents; Antidepressive Agents, Tricyclic; Bipolar Disorder; Carbamazepine; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluoxetine; Follow-Up Studies; Humans; Lithium; Male; Monoamine Oxidase Inhibitors; Selective Serotonin Reuptake Inhibitors; Valproic Acid; Verapamil | 1998 |
Anticonvulsant therapy and suicide risk in affective disorders.
Topics: Amitriptyline; Anticonvulsants; Bipolar Disorder; Carbamazepine; Double-Blind Method; Female; Follow-Up Studies; Humans; Lamotrigine; Lithium; Male; Mood Disorders; Prospective Studies; Risk Factors; Suicide; Suicide Prevention; Triazines; Valproic Acid | 1999 |
Omega 3 fatty acids in bipolar disorder: a preliminary double-blind, placebo-controlled trial.
Topics: Adult; Anticonvulsants; Bipolar Disorder; Carbamazepine; Double-Blind Method; Drug Therapy, Combination; Fatty Acids, Omega-3; Female; Humans; Lithium; Male; Middle Aged; Placebos; Psychiatric Status Rating Scales; Signal Transduction; Treatment Outcome; Valproic Acid | 1999 |
The use of primidone in the treatment of refractory bipolar disorder.
Topics: Adult; Ambulatory Care; Anticonvulsants; Antipsychotic Agents; Bipolar Disorder; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Lithium; Male; Middle Aged; Primidone; Prospective Studies; Treatment Failure; Treatment Outcome; Valproic Acid | 1999 |
Differential effect of number of previous episodes of affective disorder on response to lithium or divalproex in acute mania.
Topics: Acute Disease; Antimanic Agents; Bipolar Disorder; Double-Blind Method; Humans; Lithium; Placebos; Regression Analysis; Secondary Prevention; Severity of Illness Index; Treatment Outcome; Valproic Acid | 1999 |
Antidepressant discontinuation-related mania: critical prospective observation and theoretical implications in bipolar disorder.
Topics: Adrenergic Uptake Inhibitors; Anticonvulsants; Antidepressive Agents; Antidepressive Agents, Tricyclic; Bipolar Disorder; Carbamazepine; Drug Therapy, Combination; Humans; Lithium; Neurotransmitter Uptake Inhibitors; Prospective Studies; Selective Serotonin Reuptake Inhibitors; Substance Withdrawal Syndrome; Valproic Acid | 1999 |
A history of substance abuse complicates remission from acute mania in bipolar disorder.
Topics: Acute Disease; Adult; Anticonvulsants; Antipsychotic Agents; Bipolar Disorder; Carbamazepine; Comorbidity; Diagnosis, Dual (Psychiatry); Female; Hospitalization; Humans; Lithium; Male; Retrospective Studies; Substance-Related Disorders; Treatment Outcome; Valproic Acid | 1999 |
Tiagabine appears not to be efficacious in the treatment of acute mania.
Topics: Acute Disease; Adult; Anticonvulsants; Bipolar Disorder; Drug Therapy, Combination; Female; GABA Antagonists; Hospitalization; Humans; Lithium; Male; Middle Aged; Nipecotic Acids; Psychiatric Status Rating Scales; Risperidone; Tiagabine; Treatment Outcome; Valproic Acid | 1999 |
Medication status and polycystic ovary syndrome in women with bipolar disorder: a preliminary report.
Topics: Adolescent; Adult; Anticonvulsants; Bipolar Disorder; Drug Administration Schedule; Drug Therapy, Combination; Female; Follicle Stimulating Hormone; Hirsutism; Humans; Lithium; Menstruation Disturbances; Middle Aged; Obesity; Pilot Projects; Polycystic Ovary Syndrome; Testosterone; Valproic Acid | 2000 |
Effect size of lithium, divalproex sodium, and carbamazepine in children and adolescents with bipolar disorder.
Topics: Acute Disease; Adolescent; Age Factors; Antimanic Agents; Bipolar Disorder; Carbamazepine; Child; Dose-Response Relationship, Drug; Female; Humans; Lithium; Male; Outpatients; Pilot Projects; Psychiatric Status Rating Scales; Valproic Acid | 2000 |
Mania: differential effects of previous depressive and manic episodes on response to treatment.
Topics: Antimanic Agents; Bipolar Disorder; Depression; Double-Blind Method; Drug Tolerance; Female; Humans; Lithium; Male; Psychiatric Status Rating Scales; Recurrence; Severity of Illness Index; Treatment Outcome; Valproic Acid | 2000 |
Effects of divalproex versus lithium on length of hospital stay among patients with bipolar disorder.
Topics: Adult; Antimanic Agents; Bipolar Disorder; Connecticut; Cost-Benefit Analysis; Female; Humans; Length of Stay; Lithium; Male; Prospective Studies; Valproic Acid | 2000 |
A naturalistic comparison of clozapine, risperidone, and olanzapine in the treatment of bipolar disorder.
Topics: Adult; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Bipolar Disorder; Body Weight; Clozapine; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Lithium; Male; Olanzapine; Pirenzepine; Psychiatric Status Rating Scales; Retrospective Studies; Risperidone; Treatment Outcome; Valproic Acid | 2000 |
Inositol as an add-on treatment for bipolar depression.
Topics: Adult; Anticonvulsants; Antimanic Agents; Bipolar Disorder; Blood-Brain Barrier; Carbamazepine; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Inositol; Lithium; Male; Middle Aged; Pilot Projects; Treatment Outcome; Valproic Acid | 2000 |
Topiramate as add-on treatment for patients with bipolar mania.
Topics: Acetates; Adult; Aged; Amines; Anticonvulsants; Antimanic Agents; Bipolar Disorder; Body Mass Index; Carbamazepine; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Follow-Up Studies; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lithium; Male; Middle Aged; Topiramate; Treatment Outcome; Valproic Acid | 1999 |
Double-blind, placebo-controlled comparison of imipramine and paroxetine in the treatment of bipolar depression.
Topics: Adult; Aged; Ambulatory Care; Anticonvulsants; Antidepressive Agents, Tricyclic; Bipolar Disorder; Carbamazepine; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Imipramine; Lithium; Male; Middle Aged; Paroxetine; Placebos; Selective Serotonin Reuptake Inhibitors; Treatment Outcome; Valproic Acid | 2001 |
Olanzapine therapy in treatment-resistant psychotic mood disorders: a long-term follow-up study.
Topics: Adult; Affective Disorders, Psychotic; Aged; Anticonvulsants; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Brief Psychiatric Rating Scale; Cohort Studies; Depressive Disorder; Drug Therapy, Combination; Female; Follow-Up Studies; Hospitalization; Humans; Lithium; Male; Middle Aged; Olanzapine; Pirenzepine; Psychiatric Status Rating Scales; Psychotic Disorders; Schizophrenia; Treatment Outcome; Valproic Acid | 2001 |
Quetiapine alone and added to a mood stabilizer for serious mood disorders.
Topics: Adult; Aged; Antipsychotic Agents; Bipolar Disorder; Brief Psychiatric Rating Scale; Dibenzothiazepines; Drug Administration Schedule; Drug Therapy, Combination; Female; Hospitalization; Humans; Lithium; Male; Middle Aged; Prospective Studies; Psychiatric Status Rating Scales; Psychotic Disorders; Quetiapine Fumarate; Severity of Illness Index; Treatment Outcome; Valproic Acid; Weight Gain | 2001 |
The evolving role of topiramate among other mood stabilizers in the management of bipolar disorder.
Topics: Acetates; Acute Disease; Amines; Anticonvulsants; Antimanic Agents; Bipolar Disorder; Carbamazepine; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Lithium; Randomized Controlled Trials as Topic; Topiramate; Triazines; Valproic Acid | 2001 |
Pattern of response to divalproex, lithium, or placebo in four naturalistic subtypes of mania.
Topics: Adult; Antimanic Agents; Behavior; Bipolar Disorder; Delusions; Double-Blind Method; Euphoria; Female; Hostility; Humans; Hyperkinesis; Lithium; Male; Psychiatric Status Rating Scales; Valproic Acid | 2002 |
Combination of a mood stabilizer with risperidone or haloperidol for treatment of acute mania: a double-blind, placebo-controlled comparison of efficacy and safety.
Topics: Acute Disease; Adolescent; Adult; Aged; Antimanic Agents; Antiparkinson Agents; Antipsychotic Agents; Basal Ganglia Diseases; Bipolar Disorder; Brief Psychiatric Rating Scale; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Haloperidol; Humans; Lithium; Male; Middle Aged; Placebos; Psychiatric Status Rating Scales; Risperidone; Treatment Outcome; Valproic Acid | 2002 |
Lithium and valproate treatment of pathological gambling: a randomized single-blind study.
Topics: Anticonvulsants; Disruptive, Impulse Control, and Conduct Disorders; Drug Administration Schedule; Female; Gambling; Humans; Lithium; Male; Psychiatric Status Rating Scales; Single-Blind Method; Treatment Outcome; Valproic Acid | 2002 |
Treatment of bipolar I rapid cycling patients during dysphoric mania with olanzapine.
Topics: Adult; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Carbamazepine; Chemotherapy, Adjuvant; Female; Humans; Lithium; Male; Middle Aged; Olanzapine; Pirenzepine; Psychiatric Status Rating Scales; Time Factors; Valproic Acid | 2002 |
Chronic treatment with both lithium and sodium valproate may normalize phosphoinositol cycle activity in bipolar patients.
Topics: Adult; Algorithms; Antimanic Agents; Bipolar Disorder; Brain Chemistry; Female; Frontal Lobe; Humans; Inositol; Lithium; Magnetic Resonance Spectroscopy; Male; Phosphatidylinositols; Psychiatric Status Rating Scales; Temporal Lobe; Valproic Acid | 2002 |
Initial triple therapy of acute mania, adding lithium and valproate to neuroleptics.
Topics: Acute Disease; Adult; Aged; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Drug Therapy, Combination; Female; Hospitalization; Humans; Lithium; Male; Middle Aged; Psychiatric Status Rating Scales; Treatment Outcome; Valproic Acid | 2002 |
Initial lithium and valproate combination therapy in acute mania.
Topics: Acute Disease; Adult; Aged; Antimanic Agents; Bipolar Disorder; Drug Therapy, Combination; Female; Humans; Lithium; Male; Middle Aged; Prospective Studies; Retrospective Studies; Severity of Illness Index; Treatment Outcome; Valproic Acid | 2002 |
Chronic treatment with lithium, but not sodium valproate, increases cortical N-acetyl-aspartate concentrations in euthymic bipolar patients.
Topics: Adult; Antidepressive Agents; Antimanic Agents; Aspartic Acid; Bipolar Disorder; Cerebral Cortex; Choline; Creatine; Drug Administration Schedule; Female; Humans; Inositol; Lithium; Magnetic Resonance Spectroscopy; Male; Phosphocreatine; Valproic Acid | 2003 |
Maintenance efficacy of divalproex in the prevention of bipolar depression.
Topics: Adolescent; Adult; Aged; Bipolar Disorder; Chi-Square Distribution; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Interactions; Enzyme Inhibitors; Female; Follow-Up Studies; Humans; Lithium; Male; Middle Aged; Psychiatric Status Rating Scales; Secondary Prevention; Selective Serotonin Reuptake Inhibitors; Time Factors; Treatment Outcome; Valproic Acid | 2003 |
Combination pharmacotherapy in children and adolescents with bipolar disorder.
Topics: Adolescent; Antidepressive Agents; Antimanic Agents; Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Bipolar Disorder; Bupropion; Carbamazepine; Central Nervous System Stimulants; Child; Drug Therapy, Combination; Female; Humans; Lithium; Male; Methylphenidate; Prospective Studies; Risperidone; Selective Serotonin Reuptake Inhibitors; Valproic Acid | 2003 |
Antipsychotic-induced weight gain: bipolar disorder and leptin.
Topics: Adolescent; Adult; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Body Mass Index; Female; Humans; Leptin; Lithium; Male; Middle Aged; Olanzapine; Pirenzepine; Risperidone; Valproic Acid; Weight Gain | 2003 |
The safety and early efficacy of oral-loaded divalproex versus standard-titration divalproex, lithium, olanzapine, and placebo in the treatment of acute mania associated with bipolar disorder.
Topics: Acute Disease; Adolescent; Adult; Aged; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Diagnostic and Statistical Manual of Mental Disorders; Double-Blind Method; Drug Tolerance; Female; Humans; Lithium; Male; Middle Aged; Olanzapine; Pirenzepine; Randomized Controlled Trials as Topic; Severity of Illness Index; Titrimetry; Treatment Outcome; Valproic Acid | 2003 |
Adjunctive topiramate in bipolar II disorder.
Topics: Adult; Anticonvulsants; Antimanic Agents; Bipolar Disorder; Carbamazepine; Drug Resistance; Drug Therapy, Combination; Female; Fructose; Humans; Lithium; Male; Middle Aged; Psychiatric Status Rating Scales; Topiramate; Treatment Outcome; Valproic Acid | 2003 |
Relapse prevention in bipolar I disorder: 18-month comparison of olanzapine plus mood stabiliser v. mood stabiliser alone.
Topics: Adult; Aged; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Lithium; Male; Middle Aged; Olanzapine; Recurrence; Time Factors; Valproic Acid | 2004 |
Risperidone in combination with mood stabilizers: a 10-week continuation phase study in bipolar I disorder.
Topics: Adult; Anticonvulsants; Antipsychotic Agents; Bipolar Disorder; Brief Psychiatric Rating Scale; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Hospitalization; Humans; Lithium; Male; Psychiatric Status Rating Scales; Severity of Illness Index; Treatment Outcome; Valproic Acid | 2004 |
Pramipexole for bipolar II depression: a placebo-controlled proof of concept study.
Topics: Adult; Antidepressive Agents; Antimanic Agents; Benzothiazoles; Bipolar Disorder; Dopamine Agonists; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Lithium; Male; Middle Aged; Nerve Growth Factors; Pilot Projects; Pramipexole; Receptors, Dopamine D2; Receptors, Dopamine D3; Thiazoles; Valproic Acid | 2004 |
Psychosis in mania: specificity of its role in severity and treatment response.
Topics: Anticonvulsants; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Cluster Analysis; Delusions; Factor Analysis, Statistical; Hallucinations; Hospitalization; Humans; Lithium; Placebos; Psychiatric Status Rating Scales; Severity of Illness Index; Treatment Outcome; Valproic Acid | 2004 |
Lithium and valproic acid treatment effects on brain chemistry in bipolar disorder.
Topics: Adult; Analysis of Variance; Antimanic Agents; Bipolar Disorder; Brain; Brain Chemistry; Brain Mapping; Case-Control Studies; Echo-Planar Imaging; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Lactic Acid; Lithium; Magnetic Resonance Spectroscopy; Male; Psychiatric Status Rating Scales; Valproic Acid | 2004 |
The antidepressant effects of risperidone and olanzapine in bipolar disorder.
Topics: Adolescent; Adult; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Body Weight; Chemotherapy, Adjuvant; Depression; Female; Humans; Lithium; Male; Middle Aged; Olanzapine; Pilot Projects; Prospective Studies; Psychiatric Status Rating Scales; Risperidone; Time Factors; Valproic Acid | 2004 |
Quetiapine versus placebo in combination with lithium or divalproex for the treatment of bipolar mania.
Topics: Adolescent; Adult; Analysis of Variance; Bipolar Disorder; Dibenzothiazepines; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Lithium; Male; Middle Aged; Psychiatric Status Rating Scales; Quetiapine Fumarate; Valproic Acid | 2004 |
Lithium and valproate attenuate dextroamphetamine-induced changes in brain activation.
Topics: Adult; Anticonvulsants; Brain; Capsules; Central Nervous System Stimulants; Dextroamphetamine; Double-Blind Method; Drug Interactions; Female; Humans; Lithium; Magnetic Resonance Imaging; Male; Neuropsychological Tests; Oxygen; Patient Selection; Time Factors; Valproic Acid | 2005 |
Effectiveness and medical costs of divalproex versus lithium in the treatment of bipolar disorder: results of a naturalistic clinical trial.
Topics: Adult; Anticonvulsants; Antimanic Agents; Bipolar Disorder; Carbamazepine; Drug Costs; Drug Therapy, Combination; Female; Health Care Costs; Health Status; Hospitalization; Humans; Lithium; Male; Outcome Assessment, Health Care; Quality of Life; Treatment Outcome; Valproic Acid | 2005 |
Valproate attenuates dextroamphetamine-induced subjective changes more than lithium.
Topics: Adolescent; Adult; Affect; Anticonvulsants; Antimanic Agents; Bipolar Disorder; Central Nervous System Stimulants; Dextroamphetamine; Dose-Response Relationship, Drug; Double-Blind Method; Female; Hemodynamics; Humans; Lithium; Male; Middle Aged; Valproic Acid | 2005 |
Relationship of mania symptomatology to maintenance treatment response with divalproex, lithium, or placebo.
Topics: Adult; Antimanic Agents; Bipolar Disorder; Double-Blind Method; Drug Evaluation; Drug Tolerance; Female; Humans; Lithium; Male; Middle Aged; Psychiatric Status Rating Scales; Time Factors; Valproic Acid | 2005 |
Differential effects of chronic lithium and valproate on brain activation in healthy volunteers.
Topics: Adult; Attention; Bipolar Disorder; Brain; Double-Blind Method; Female; Humans; Lithium; Magnetic Resonance Imaging; Male; Memory; Valproic Acid | 2005 |
A 20-month, double-blind, maintenance trial of lithium versus divalproex in rapid-cycling bipolar disorder.
Topics: Adolescent; Adult; Anticonvulsants; Bipolar Disorder; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Lithium; Longitudinal Studies; Male; Patient Dropouts; Psychiatric Status Rating Scales; Secondary Prevention; Treatment Outcome; Valproic Acid | 2005 |
Combination lithium and divalproex sodium in pediatric bipolar symptom re-stabilization.
Topics: Adolescent; Antimanic Agents; Bipolar Disorder; Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Lithium; Male; Prospective Studies; Valproic Acid | 2006 |
Much improved outcome with gabapentin-divalproex combination in adults with bipolar disorders and developmental disabilities.
Topics: Adolescent; Adult; Amines; Antimanic Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids; Developmental Disabilities; Drug Combinations; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lithium; Male; Middle Aged; Psychiatric Status Rating Scales; Treatment Outcome; Valproic Acid | 2006 |
Reduced suicidal ideation in bipolar I disorder mixed-episode patients in a placebo-controlled trial of olanzapine combined with lithium or divalproex.
Topics: Adult; Anticonvulsants; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Double-Blind Method; Female; Humans; Lithium; Male; Middle Aged; Olanzapine; Placebos; Principal Component Analysis; Psychiatric Status Rating Scales; Risk Factors; Suicide; Treatment Outcome; Valproic Acid | 2006 |
Depression symptom ratings in geriatric patients with bipolar mania.
Topics: Aged; Aged, 80 and over; Antimanic Agents; Bipolar Disorder; Depressive Disorder; Double-Blind Method; Female; Geriatric Psychiatry; Humans; Lithium; Male; Middle Aged; Psychiatric Status Rating Scales; Regression Analysis; United States; Valproic Acid | 2011 |
Efficacy of aripiprazole adjunctive to lithium or valproate in the long-term treatment of patients with bipolar I disorder with an inadequate response to lithium or valproate monotherapy: a multicenter, double-blind, randomized study.
Topics: Adult; Antimanic Agents; Aripiprazole; Bipolar Disorder; Confidence Intervals; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Lithium; Longitudinal Studies; Male; Middle Aged; Piperazines; Psychiatric Status Rating Scales; Quinolones; Time Factors; Treatment Outcome; Valproic Acid | 2011 |
Estimation of resource utilisation difference between lithium and valproate treatment groups from the VALID study.
Topics: Adult; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Cost-Benefit Analysis; Female; Health Services; Humans; Lithium; Male; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Surveys and Questionnaires; Valproic Acid | 2011 |
Efficacy and safety of adjunctive oral ziprasidone for acute treatment of depression in patients with bipolar I disorder: a randomized, double-blind, placebo-controlled trial.
Topics: Acute Disease; Adolescent; Adult; Aged; Antimanic Agents; Bipolar Disorder; Depressive Disorder, Major; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Lamotrigine; Lithium; Male; Middle Aged; Piperazines; Serotonin Antagonists; Thiazoles; Treatment Outcome; Triazines; Valproic Acid; Young Adult | 2011 |
Treatment of suicide attempters with bipolar disorder: a randomized clinical trial comparing lithium and valproate in the prevention of suicidal behavior.
Topics: Adult; Antimanic Agents; Bipolar Disorder; Double-Blind Method; Female; Humans; Lithium; Male; Middle Aged; Suicide Prevention; Suicide, Attempted; Treatment Outcome; Valproic Acid | 2011 |
Safety and efficacy of olanzapine monotherapy and olanzapine with a mood stabilizer in 18-week treatment of manic/mixed episodes for Japanese patients with bipolar I disorder.
Topics: Adult; Affect; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Carbamazepine; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Japan; Lithium; Male; Middle Aged; Olanzapine; Prolactin; Psychiatric Status Rating Scales; Time Factors; Treatment Outcome; Valproic Acid | 2012 |
Characterizing relapse prevention in bipolar disorder with adjunctive ziprasidone: clinical and methodological implications.
Topics: Antipsychotic Agents; Bipolar Disorder; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Follow-Up Studies; Humans; Lithium; Piperazines; Secondary Prevention; Thiazoles; Treatment Outcome; Valproic Acid | 2013 |
Investigation into the long-term metabolic effects of aripiprazole adjunctive to lithium, valproate, or lamotrigine.
Topics: Adult; Antipsychotic Agents; Aripiprazole; Bipolar Disorder; Body Weight; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Lamotrigine; Lithium; Male; Metabolic Syndrome; Middle Aged; Obesity; Overweight; Piperazines; Quinolones; Time Factors; Treatment Outcome; Triazines; Valproic Acid | 2013 |
Maintenance treatment with quetiapine when combined with either lithium or divalproex in bipolar I disorder: analysis of two large randomized, placebo-controlled trials.
Topics: Adult; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Dibenzothiazepines; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Lithium; Male; Middle Aged; Quetiapine Fumarate; Secondary Prevention; Treatment Outcome; Valproic Acid | 2013 |
A pilot study of plasma metabolomic patterns from patients treated with ketamine for bipolar depression: evidence for a response-related difference in mitochondrial networks.
Topics: Adult; Antidepressive Agents; Biomarkers, Pharmacological; Bipolar Disorder; Cross-Over Studies; Depressive Disorder, Treatment-Resistant; Drug Therapy, Combination; Female; Humans; Ketamine; Lithium; Lysophosphatidylcholines; Lysophospholipids; Male; Metabolome; Middle Aged; Pilot Projects; Valproic Acid; Young Adult | 2014 |
Lithium and Valproate Levels Do Not Correlate with Ketamine's Antidepressant Efficacy in Treatment-Resistant Bipolar Depression.
Topics: Adult; Antidepressive Agents; Bipolar Disorder; Cross-Over Studies; Depressive Disorder, Treatment-Resistant; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Ketamine; Lithium; Male; Middle Aged; Psychiatric Status Rating Scales; Treatment Outcome; Valproic Acid | 2015 |
Prophylactic efficacy of lithium, valproic acid, and carbamazepine in the maintenance phase of bipolar disorder: a naturalistic study.
Topics: Adult; Antimanic Agents; Bipolar Disorder; Carbamazepine; Female; Follow-Up Studies; Humans; Lithium; Male; Middle Aged; Post-Exposure Prophylaxis; Secondary Prevention; Treatment Outcome; Valproic Acid | 2016 |
Effect of lurasidone on meaningful change in health-related quality of life in patients with bipolar depression.
Topics: Adult; Antipsychotic Agents; Bipolar Disorder; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Lithium; Lurasidone Hydrochloride; Male; Quality of Life; Valproic Acid; Young Adult | 2016 |
Assessing bipolar disorder in the older adult: the GERI-BD toolbox.
Topics: Aged; Antimanic Agents; Bipolar Disorder; Depressive Disorder, Major; Double-Blind Method; Drug Therapy, Combination; Female; Geriatric Assessment; Humans; Lithium; Male; Middle Aged; Mood Disorders; Valproic Acid | 2018 |
Risperidone adjunctive therapy duration in the maintenance treatment of bipolar I disorder: A post hoc analysis.
Topics: Administration, Oral; Adolescent; Adult; Aged; Antipsychotic Agents; Bipolar Disorder; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Lithium; Male; Middle Aged; Risperidone; Secondary Prevention; Treatment Outcome; Valproic Acid; Young Adult | 2019 |
Sequential Multiple Assignment Randomized Treatment (SMART) for Bipolar Disorder at Any Phase of Illness and at least Mild Symptom Severity.
Topics: Antipsychotic Agents; Bipolar Disorder; Double-Blind Method; Drug Therapy, Combination; Humans; Lamotrigine; Lithium; Quetiapine Fumarate; Treatment Outcome; Valproic Acid | 2020 |
Personality profile and therapeutic response to lithium carbonate and sodium valproate in mania with psychotic features.
Topics: Antimanic Agents; Humans; Lithium; Lithium Carbonate; Mania; Personality; Valproic Acid | 2022 |
Lithium plus antipsychotics or anticonvulsants for bipolar disorder: Comparing clinical response and metabolic changes.
Topics: Adult; Anticonvulsants; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Drug Therapy, Combination; Female; Humans; Lithium; Male; Metabolic Syndrome; Valproic Acid | 2023 |
Adjunctive lumateperone (ITI-007) in the treatment of bipolar depression: Results from a randomized placebo-controlled clinical trial.
Topics: Antipsychotic Agents; Bipolar Disorder; Depressive Disorder, Major; Double-Blind Method; Drug Therapy, Combination; Humans; Lithium; Treatment Outcome; Valproic Acid | 2023 |
Antisuicidal effect of lithum in bipolar disorder: is there an age-specific effect?
Topics: Adult; Age Factors; Aged; Bipolar Disorder; Humans; Lithium; Middle Aged; Suicidal Ideation; Valproic Acid | 2023 |
251 other study(ies) available for valproic acid and lithium
| Article | Year |
|---|---|
[Manic-depressive psychoses. Chronic treatment with tricyclic antidepressive agents].
Topics: Adult; Aged; Antidepressive Agents, Tricyclic; Bipolar Disorder; Female; Humans; Lithium; Male; Middle Aged; Time Factors; Valproic Acid | 1977 |
[Clinical study of the normothymic effect of dipropylacetamide].
Topics: Adolescent; Adult; Drug Evaluation; Female; Humans; Lithium; Male; Mental Disorders; Middle Aged; Psychotropic Drugs; Valerates; Valproic Acid | 1976 |
[Duration of antidepressive treatments].
Topics: Antidepressive Agents, Tricyclic; Bupropion; Carbamazepine; Depressive Disorder; Dose-Response Relationship, Drug; Humans; Lithium; Monoamine Oxidase Inhibitors; Serotonin Antagonists; Valproic Acid | 1992 |
GABA receptor alterations after chronic lithium administration. Comparison with carbamazepine and sodium valproate.
Topics: Animals; Baclofen; Brain; Carbamazepine; In Vitro Techniques; Lithium; Male; Muscimol; Rats; Rats, Inbred WKY; Receptors, GABA-A; Valproic Acid | 1992 |
Algorithm for patient management of acute manic states: lithium, valproate, or carbamazepine?
Topics: Acute Disease; Algorithms; Bipolar Disorder; Carbamazepine; Humans; Lithium; Valproic Acid | 1992 |
Valproate for rapid-cycling unipolar affective disorder.
Topics: Adult; Depressive Disorder; Drug Therapy, Combination; Female; Humans; Lithium; Longitudinal Studies; Recurrence; Valproic Acid | 1991 |
Life events and the course of bipolar disorder.
Topics: Adult; Ambulatory Care; Antipsychotic Agents; Bipolar Disorder; Carbamazepine; Female; Follow-Up Studies; Humans; Life Change Events; Lithium; Male; Patient Compliance; Recurrence; Valproic Acid | 1990 |
Valproate use in the older manic patient.
Topics: Age Factors; Aged; Antipsychotic Agents; Bipolar Disorder; Combined Modality Therapy; Drug Evaluation; Drug Therapy, Combination; Electroconvulsive Therapy; Female; Hospitals, Psychiatric; Hospitals, State; Humans; Institutionalization; Lithium; Male; Middle Aged; Psychiatric Status Rating Scales; Valproic Acid | 1990 |
Four cases of obstructive sleep apnea associated with treatment-resistant mania.
Topics: Adult; Bipolar Disorder; Clonazepam; Female; Follow-Up Studies; Hospitalization; Humans; Lithium; Middle Aged; Patient Compliance; Perphenazine; Respiratory Therapy; Sleep Apnea Syndromes; Valproic Acid; Weight Gain | 1991 |
[Therapeutic monitoring of drug concentration in blood. Are the analyses correctly ordered?].
Topics: Blood Chemical Analysis; Carbamazepine; Digoxin; Drug Administration Schedule; Humans; Lithium; Monitoring, Physiologic; Surveys and Questionnaires; Theophylline; Valproic Acid | 1991 |
GABA and circadian timekeeping: implications for manic-depression and sleep disorders.
Topics: 4-Aminobutyrate Transaminase; Acetylcholine; Aldehyde Oxidoreductases; Animals; Benzodiazepines; Bipolar Disorder; Carbamazepine; Circadian Rhythm; Enzyme Induction; gamma-Aminobutyric Acid; Glutamate Dehydrogenase; Humans; Hypothalamus, Middle; Lithium; Models, Biological; Receptors, GABA-A; Sleep Wake Disorders; Succinate-Semialdehyde Dehydrogenase; Suprachiasmatic Nucleus; Valproic Acid | 1986 |
The use of alternative drug therapy in nine patients with recurrent affective disorder resistant to conventional prophylaxis.
Topics: Adult; Aged; Bipolar Disorder; Carbamazepine; Drug Therapy, Combination; Female; Humans; Lithium; Middle Aged; Recurrence; Valproic Acid | 1986 |
New developments in long-term preventive therapy.
Topics: Antidepressive Agents; Bipolar Disorder; Depressive Disorder; Diethylcarbamazine; Dose-Response Relationship, Drug; Humans; Lithium; Time Factors; Valproic Acid | 1986 |
Lithium-induced downbeat nystagmus.
Topics: Adult; Bipolar Disorder; Electrooculography; Female; Haloperidol; Humans; Lithium; Middle Aged; Nystagmus, Pathologic; Valproic Acid | 1988 |
[New developments in preventive therapy of manic-depressive disease].
Topics: Antidepressive Agents; Carbamazepine; Depressive Disorder; Dose-Response Relationship, Drug; Humans; Lithium; Long-Term Care; Psychotropic Drugs; Valproic Acid | 1988 |
Combined lithium and valproate treatment and subsequent withdrawal: serotonergic mechanism of their interaction in discrete brain regions.
Topics: Animals; Brain; Brain Chemistry; Drug Interactions; Humans; Lithium; Lithium Carbonate; Male; Rats; Rats, Inbred Strains; Serotonin; Substance Withdrawal Syndrome; Valproic Acid | 1985 |
[Effect of lithium, carbamazepine, ca-valproate and diazepam on changes in social isolation-induced behavior in mice].
Topics: Aggression; Animals; Behavior, Animal; Carbamazepine; Diazepam; Lithium; Male; Mice; Motor Activity; Serotonin; Social Isolation; Stress, Physiological; Valproic Acid | 1985 |
[Comparison of the side-effects of lithium and dipropylacetamide (Depamide)].
Topics: Humans; Lithium; Valproic Acid | 1983 |
Myo-inositol monophosphatase: diverse effects of lithium, carbamazepine, and valproate.
Topics: Animals; Brain; Calcium; Carbamazepine; Cattle; Enzyme Inhibitors; Lithium; Magnesium; Phosphoric Monoester Hydrolases; Valproic Acid | 1995 |
Sucralfate in bipolar patients with valproate intolerance.
Topics: Bipolar Disorder; Drug Therapy, Combination; Female; Humans; Lithium; Middle Aged; Sucralfate; Valproic Acid | 1995 |
Valproate and carbamazepine join lithium as primary treatments for bipolar disorder.
Topics: Bipolar Disorder; Carbamazepine; Electroconvulsive Therapy; Humans; Lithium; Valproic Acid | 1995 |
A clinically significant interaction between clozapine and valproate.
Topics: Adult; Arousal; Bipolar Disorder; Clozapine; Confusion; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Humans; Lithium; Male; Orientation; Psychotic Disorders; Speech Disorders; Valproic Acid | 1995 |
Lithium: the present and the future.
Topics: Acute Disease; Bipolar Disorder; Carbamazepine; Depressive Disorder; Drug Interactions; Female; Humans; Lithium; Pregnancy; Pregnancy Complications; Puerperal Disorders; Treatment Outcome; Valproic Acid | 1995 |
Choosing lithium, anticonvulsant, or electroconvulsant therapy for mood disorders.
Topics: Anticonvulsants; Bipolar Disorder; Carbamazepine; Controlled Clinical Trials as Topic; Electroconvulsive Therapy; Humans; Lithium; Mood Disorders; Valproic Acid | 1995 |
Anticonvulsant therapy for mood disorders.
Topics: Affect; Anticonvulsants; Bipolar Disorder; Carbamazepine; Humans; Lithium; Valproic Acid | 1994 |
Combining lithium and sodium valproate for bipolar disorder.
Topics: Bipolar Disorder; Drug Therapy, Combination; Female; Humans; Lithium; Male; Middle Aged; Valproic Acid | 1994 |
Safety and efficacy of divalproex sodium in elderly bipolar patients.
Topics: Aged; Bipolar Disorder; Drug Therapy, Combination; Female; Humans; Lithium; Male; Treatment Outcome; Valproic Acid | 1994 |
Efficacy of divalproex vs lithium and placebo in mania.
Topics: Bipolar Disorder; Humans; Lithium; Valproic Acid | 1994 |
Divalproex sodium in the treatment of refractory affective disorders.
Topics: Adult; Aged; Bipolar Disorder; Carbamazepine; Depressive Disorder; Drug Therapy, Combination; Female; Humans; Lithium; Male; Middle Aged; Psychotic Disorders; Recurrence; Retrospective Studies; Treatment Outcome; Valproic Acid | 1993 |
Effects of haloperidol, lithium, and valproate on phosphoinositide turnover in rat brain.
Topics: Animals; Brain Chemistry; Carbachol; Corpus Striatum; Drug Interactions; Haloperidol; Lithium; Male; Norepinephrine; Phosphatidylinositols; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Valproic Acid | 1993 |
[A study on the pharmacological mechanism of the mood stabilizer--the changes of the rat brain concentrations of monoamines and their metabolites after the administration of Li, CBZ and VPA for 14 days].
Topics: Animals; Biogenic Monoamines; Brain; Carbamazepine; Lithium; Male; Rats; Rats, Sprague-Dawley; Time Factors; Valproic Acid | 1993 |
Clinical correlates of valproate augmentation in refractory bipolar disorder.
Topics: Adult; Antidepressive Agents; Bipolar Disorder; Drug Therapy, Combination; Female; Hospitalization; Humans; Lithium; Male; Probability; Retrospective Studies; Treatment Outcome; Valproic Acid | 1993 |
Trends in pharmacotherapy of Schizoaffective and bipolar affective disorders: a 5-year naturalistic study.
Topics: Bipolar Disorder; Carbamazepine; Clinical Trials as Topic; Drug Therapy, Combination; Drug Utilization; Hospitalization; Humans; Information Systems; Lithium; Psychotic Disorders; Survival Analysis; Treatment Outcome; Valproic Acid | 1996 |
Treatment of dysphoric mania with nefazodone.
Topics: Adult; Antidepressive Agents, Second-Generation; Bipolar Disorder; Drug Therapy, Combination; Female; Humans; Lithium; Piperazines; Treatment Outcome; Triazoles; Valproic Acid | 1996 |
A pharmacoeconomic model of divalproex vs. lithium in the acute and prophylactic treatment of bipolar I disorder.
Topics: Acute Disease; Ambulatory Care; Bipolar Disorder; Costs and Cost Analysis; Decision Support Techniques; Dose-Response Relationship, Drug; Drug Costs; Economics, Pharmaceutical; Health Care Costs; Hospitalization; Humans; Lithium; Recurrence; Treatment Outcome; Valproic Acid | 1996 |
Medication optimization during clozapine treatment.
Topics: 1-Naphthylamine; Adult; Clozapine; Drug Therapy, Combination; Humans; Lithium; Male; Obsessive-Compulsive Disorder; Psychotic Disorders; Selective Serotonin Reuptake Inhibitors; Sertraline; Treatment Outcome; Valproic Acid | 1996 |
Lithium-associated cognitive and functional deficits reduced by a switch to divalproex sodium: a case series.
Topics: Adult; Bipolar Disorder; Cognition Disorders; Creativity; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Lithium; Male; Middle Aged; Motivation; Quality of Life; Valproic Acid | 1996 |
National Institute of Mental Health Workshop Report on the Treatment of Bipolar Disorder.
Topics: Antidepressive Agents; Bipolar Disorder; Carbamazepine; Education; Humans; Lithium; Valproic Acid | 1996 |
A novel action of lithium: stimulation of glutamate release and inositol 1,4,5 trisphosphate accumulation via activation of the N-methyl D-aspartate receptor in monkey and mouse cerebral cortex slices.
Topics: Animals; Calcium Channels; Cerebral Cortex; Cyclopentanes; Excitatory Amino Acid Antagonists; Glutamic Acid; Haplorhini; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Lithium; Mice; Piperazines; Receptors, Cytoplasmic and Nuclear; Receptors, N-Methyl-D-Aspartate; Valproic Acid | 1996 |
Lithium and valproate combined administration: acute behavioural effects and drug plasma levels.
Topics: Analysis of Variance; Animals; Anticonvulsants; Behavior, Animal; Drug Interactions; Female; Flame Ionization; Hyponatremia; Lithium; Peritoneal Dialysis; Rats; Rats, Wistar; Sodium; Valproic Acid | 1996 |
Acute treatment of bipolar disorder with adjunctive risperidone in outpatients.
Topics: Adult; Antipsychotic Agents; Bipolar Disorder; Carbamazepine; Drug Therapy, Combination; Female; Humans; Lithium; Male; Middle Aged; Psychiatric Status Rating Scales; Retrospective Studies; Risperidone; Treatment Outcome; Valproic Acid | 1997 |
The antibipolar drug valproate mimics lithium in stimulating glutamate release and inositol 1,4,5-trisphosphate accumulation in brain cortex slices but not accumulation of inositol monophosphates and bisphosphates.
Topics: Animals; Antidepressive Agents; Antimanic Agents; Bipolar Disorder; Cerebral Cortex; Drug Interactions; Glutamic Acid; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Lithium; Male; Mice; Mice, Inbred ICR; Molecular Mimicry; Receptors, N-Methyl-D-Aspartate; Valproic Acid | 1997 |
Chronic neuroleptic exposure in bipolar outpatients.
Topics: Adult; Aged; Ambulatory Care; Antidepressive Agents; Antipsychotic Agents; Bipolar Disorder; Community Mental Health Centers; Connecticut; Drug Therapy, Combination; Drug Utilization; Female; Humans; Lithium; Male; Medical Records; Middle Aged; Valproic Acid | 1997 |
Comparison of valproic acid and lithium in mania.
Topics: Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Drug Administration Schedule; Drug Industry; Drug Therapy, Combination; Humans; Lithium; Research Design; Research Support as Topic; Retrospective Studies; Valproic Acid | 1997 |
Mania.
Topics: Antimanic Agents; Bipolar Disorder; Humans; Lithium; Valproic Acid | 1997 |
Is divalproex a cost-effective alternative in the acute and prophylactic treatment of bipolar I disorder?
Topics: Acute Disease; Bipolar Disorder; Cost-Benefit Analysis; Drug Costs; Health Care Costs; Hospitalization; Humans; Length of Stay; Lithium; Research Design; Treatment Outcome; Valproic Acid | 1997 |
Rapid efficacy of olanzapine augmentation in nonpsychotic bipolar mixed states.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Drug Therapy, Combination; Female; Humans; Lithium; Male; Middle Aged; Olanzapine; Pirenzepine; Thyroxine; Valproic Acid | 1998 |
Cost-effectiveness of divalproex versus lithium.
Topics: Bipolar Disorder; Cost-Benefit Analysis; Drug Administration Schedule; Drug Costs; Hospitalization; Humans; Length of Stay; Lithium; Lithium Carbonate; Research Design; Valproic Acid | 1997 |
Rapid titration of mood stabilizers predicts remission from mixed or pure mania in bipolar patients.
Topics: Adult; Analysis of Variance; Bipolar Disorder; Carbamazepine; Drug Administration Schedule; Drug Therapy, Combination; Female; Hospital Records; Hospitalization; Humans; Lithium; Logistic Models; Male; Middle Aged; Probability; Psychiatric Status Rating Scales; Retrospective Studies; Severity of Illness Index; Survival Analysis; Treatment Outcome; Valproic Acid | 1998 |
Medication compliance among patients with bipolar disorder and substance use disorder.
Topics: Adult; Benzodiazepines; Bipolar Disorder; Carbamazepine; Comorbidity; Female; Humans; Lithium; Male; Patient Compliance; Psychiatric Status Rating Scales; Psychotropic Drugs; Retrospective Studies; Selective Serotonin Reuptake Inhibitors; Substance-Related Disorders; Valproic Acid | 1998 |
Use of mood stabilizers by hospitalized geriatric patients with bipolar disorder.
Topics: Aged; Analysis of Variance; Antimanic Agents; Bipolar Disorder; Carbamazepine; Female; Geriatric Psychiatry; Hospitalization; Humans; Length of Stay; Lithium; Male; Middle Aged; Retrospective Studies; Treatment Outcome; Valproic Acid | 1998 |
Lamotrigine inhibits monoamine uptake in vitro and modulates 5-hydroxytryptamine uptake in rats.
Topics: Acetates; Amines; Animals; Anticonvulsants; Biogenic Amines; Blood Platelets; Brain; Carbamazepine; Cyclohexanecarboxylic Acids; Dopamine; Dopamine Uptake Inhibitors; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Lithium; Male; Norepinephrine; p-Chloroamphetamine; Phenytoin; Rats; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Agents; Serotonin Syndrome; Synaptosomes; Tetrodotoxin; Triazines; Valproic Acid; Zonisamide | 1998 |
Classic mania: treatment response to divalproex or lithium.
Topics: Bipolar Disorder; Depressive Disorder; Humans; Lithium; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Treatment Outcome; Valproic Acid | 1998 |
The naturalistic course of pharmacologic treatment of children with maniclike symptoms: a systematic chart review.
Topics: Adolescent; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Bipolar Disorder; Carbamazepine; Central Nervous System Stimulants; Child; Clinical Protocols; Comorbidity; Dose-Response Relationship, Drug; Drug Administration Schedule; Follow-Up Studies; Humans; Lithium; Medical Records; Mental Disorders; Psychiatric Status Rating Scales; Recurrence; Retrospective Studies; Selective Serotonin Reuptake Inhibitors; Survival Analysis; Treatment Outcome; Valproic Acid | 1998 |
The mood-stabilizing agents lithium and valproate robustly increase the levels of the neuroprotective protein bcl-2 in the CNS.
Topics: Affect; Animals; Antimanic Agents; Brain Chemistry; Frontal Lobe; Gene Expression; Lithium; Male; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Inbred WKY; RNA, Messenger; Transcription Factors; Valproic Acid | 1999 |
Differential display PCR reveals novel targets for the mood-stabilizing drug valproate including the molecular chaperone GRP78.
Topics: Animals; Antimanic Agents; Carbamazepine; Carrier Proteins; Dose-Response Relationship, Drug; Endoplasmic Reticulum Chaperone BiP; Gene Expression; Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Lithium; Male; Molecular Chaperones; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; RNA, Messenger; Transcription, Genetic; Valproic Acid | 1999 |
Evidence of the activity of lithium on 5-HT1B receptors in the mouse forced swimming test: comparison with carbamazepine and sodium valproate.
Topics: Animals; Antimanic Agents; Carbamazepine; Dose-Response Relationship, Drug; Drug Interactions; Lithium; Mice; Motor Activity; Piperidines; Pyridines; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Serotonin Receptor Agonists; Swimming; Valproic Acid | 1999 |
Introduction: the use of mood stabilizers in the treatment of psychiatric disorders.
Topics: Anticonvulsants; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Carbamazepine; Humans; Lithium; Mental Disorders; Mood Disorders; Valproic Acid | 1999 |
Efficacy of lithium vs. valproate in the treatment of mania in the elderly: a retrospective study.
Topics: Age Factors; Age of Onset; Aged; Anticonvulsants; Antimanic Agents; Bipolar Disorder; Female; Hospital Records; Hospitalization; Humans; Lithium; Male; Regression Analysis; Retrospective Studies; Severity of Illness Index; Treatment Outcome; Valproic Acid | 1999 |
Valproate with lithium and carbamazepine in bipolar disorder.
Topics: Bipolar Disorder; Carbamazepine; Clinical Trials as Topic; Cross-Over Studies; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Humans; Lithium; Prospective Studies; Research Design; Valproic Acid | 1999 |
Pharmacoeconomic and health outcome comparison of lithium and divalproex in a VA geriatric nursing home population: influence of drug-related morbidity on total cost of treatment.
Topics: Aged; Antimanic Agents; Cohort Studies; Drug Costs; Drug Monitoring; Health Care Costs; Hospitalization; Hospitals, Veterans; Humans; Intensive Care Units; Lithium; Los Angeles; Retrospective Studies; Skilled Nursing Facilities; Valproic Acid | 1999 |
Mood stabilizer combinations for bipolar disorder.
Topics: Acetates; Adolescent; Age Factors; Amines; Antimanic Agents; Bipolar Disorder; Child; Cyclohexanecarboxylic Acids; Drug Eruptions; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Lithium; Triazines; Valproic Acid | 1999 |
Therapeutic drug monitoring of mood stabilizers in Medicaid patients with bipolar disorder.
Topics: Adolescent; Adult; Bipolar Disorder; Blood Chemical Analysis; Carbamazepine; Case Management; Drug Monitoring; Female; Health Care Costs; Humans; Kidney Function Tests; Lithium; Male; Managed Care Programs; Medicaid; Middle Aged; Thyroid Function Tests; United States; Valproic Acid | 1999 |
Isotretinoin treatment of a woman with bipolar disorder.
Topics: Acne Vulgaris; Adult; Bipolar Disorder; Comorbidity; Drug Therapy, Combination; Female; Humans; Isotretinoin; Keratolytic Agents; Lithium; Perphenazine; Valproic Acid | 1999 |
Inhibition of the high affinity myo-inositol transport system: a common mechanism of action of antibipolar drugs?
Topics: Adrenergic Uptake Inhibitors; Amitriptyline; Animals; Antimanic Agents; Astrocytes; Biological Transport; Brain; Carbamazepine; Carrier Proteins; Heat-Shock Proteins; Humans; Inositol; Lithium; Membrane Proteins; Rats; Rats, Wistar; RNA, Messenger; Symporters; Time Factors; Tumor Cells, Cultured; Valproic Acid | 1999 |
Modulation of carbachol-stimulated AP-1 DNA binding activity by therapeutic agents for bipolar disorder in human neuroblastoma SH-SY5Y cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Antipsychotic Agents; Bipolar Disorder; Calcium; Calcium Signaling; Carbachol; Carbamazepine; Chelating Agents; DNA; Dose-Response Relationship, Drug; Edetic Acid; Egtazic Acid; Gene Expression Regulation; Humans; Indoles; Ionomycin; Ionophores; Lithium; Muscarinic Agonists; Nerve Tissue Proteins; Neuroblastoma; Neurons; Phosphatidylinositols; Protein Binding; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Tumor Cells, Cultured; Valproic Acid | 1999 |
Lamotrigine as prophylaxis against steroid-induced mania.
Topics: Adult; Anti-Inflammatory Agents; Antimanic Agents; Bipolar Disorder; Contraindications; Female; Humans; Lamotrigine; Lithium; Nephritis, Interstitial; Prednisone; Triazines; Valproic Acid | 1999 |
Different mechanisms of protection against apoptosis by valproate and Li+.
Topics: Animals; Apoptosis; Cells, Cultured; Cerebellum; Chromones; Enzyme Inhibitors; Insulin; Lithium; Membrane Fluidity; Morpholines; Neuroprotective Agents; Phosphoinositide-3 Kinase Inhibitors; Potassium; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Signal Transduction; Valproic Acid | 1999 |
Low-dose lithium augmentation of divalproex in geriatric mania.
Topics: Acute Disease; Aged; Antimanic Agents; Bipolar Disorder; Cognition Disorders; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Overdose; Drug Therapy, Combination; Female; Humans; Lithium; Male; Treatment Outcome; Valproic Acid | 2000 |
Expression of yeast INM1 encoding inositol monophosphatase is regulated by inositol, carbon source and growth stage and is decreased by lithium and valproate.
Topics: Amino Acid Sequence; Animals; Carbon; Cattle; Escherichia coli; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Fungal; Genotype; Humans; Inositol; Lithium; Molecular Sequence Data; Open Reading Frames; Phosphoric Monoester Hydrolases; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Sequence Alignment; Sequence Homology, Amino Acid; Valproic Acid; Xenopus laevis | 2000 |
Clinical and preclinical evidence for the neurotrophic effects of mood stabilizers: implications for the pathophysiology and treatment of manic-depressive illness.
Topics: Affect; Antimanic Agents; Atrophy; Bipolar Disorder; Brain; Calcium-Calmodulin-Dependent Protein Kinases; Cell Death; Genes, bcl-2; Humans; Lithium; Magnetic Resonance Imaging; Neuroprotective Agents; RNA, Messenger; Valproic Acid | 2000 |
Difficulties in diagnosis and management of bipolar disorder: three case presentations.
Topics: Adult; Anticonvulsants; Antipsychotic Agents; Bipolar Disorder; Carbamazepine; Combined Modality Therapy; Comorbidity; Female; Humans; Lithium; Male; Psychotherapy; Substance-Related Disorders; Treatment Refusal; Valproic Acid | 2000 |
Pharmacologic treatment of patients hospitalized with the diagnosis of schizoaffective disorder.
Topics: Anticonvulsants; Antidepressive Agents; Antimanic Agents; Antipsychotic Agents; Drug Therapy, Combination; Hospitalization; Lithium; Psychotic Disorders; Valproic Acid | 2001 |
Pharmacologic loading in the treatment of acute mania.
Topics: Acute Disease; Anticonvulsants; Antimanic Agents; Bipolar Disorder; Carbamazepine; Dose-Response Relationship, Drug; Humans; Lithium; Valproic Acid | 2000 |
Lithium and valproate decrease inositol mass and increase expression of the yeast INO1 and INO2 genes for inositol biosynthesis.
Topics: Basic Helix-Loop-Helix Transcription Factors; DNA-Binding Proteins; Fungal Proteins; Gene Expression Regulation, Fungal; Genes, Fungal; Inositol; Lithium; Repressor Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Transcription Factors; Valproic Acid | 2001 |
Overexpression of components of the Frizzled-Dishevelled cascade results in apoptotic cell death, mediated by beta-catenin.
Topics: Adaptor Proteins, Signal Transducing; Animals; Apoptosis; beta Catenin; Cell Line; Chlorocebus aethiops; Chromones; COS Cells; Cytoskeletal Proteins; Dishevelled Proteins; Drosophila Proteins; Gene Expression; Humans; Intracellular Signaling Peptides and Proteins; Lithium; Membrane Proteins; Morpholines; PC12 Cells; Phosphoproteins; Protein Biosynthesis; Proteins; Rats; Signal Transduction; Trans-Activators; Valproic Acid; Virulence Factors, Bordetella | 2001 |
Molecular cloning of a novel isoform of diphosphoinositol polyphosphate phosphohydrolase: a potential target of lithium therapy.
Topics: Acid Anhydride Hydrolases; Amino Acid Sequence; Animals; Anticonvulsants; Base Sequence; Brain; Carbamazepine; Cloning, Molecular; DNA, Complementary; Inositol Phosphates; Lithium; Male; Molecular Sequence Data; Neurons; Protein Isoforms; Psychotropic Drugs; Rats; Rats, Wistar; RNA, Messenger; Signal Transduction; Valproic Acid | 2001 |
Chronic valproate treatment decreases the in vivo turnover of arachidonic acid in brain phospholipids: a possible common effect of mood stabilizers.
Topics: Acyl Coenzyme A; Animals; Antimanic Agents; Arachidonic Acid; Brain; Brain Chemistry; Fatty Acids; Fatty Acids, Nonesterified; Gene Expression; Kinetics; Lithium; Male; Phospholipases A; Phospholipids; Rats; Rats, Inbred F344; Tritium; Valproic Acid | 2001 |
Introduction: the role of anticonvulsants as mood stabilizers.
Topics: Anticonvulsants; Bipolar Disorder; Depressive Disorder; Humans; Lamotrigine; Lithium; Terminology as Topic; Triazines; Valproic Acid | 2001 |
Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen.
Topics: Acetylation; Animals; Anticonvulsants; Antimanic Agents; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Dose-Response Relationship, Drug; Glycogen Synthase Kinase 3; Green Fluorescent Proteins; Histone Deacetylase 1; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Humans; Hydroxamic Acids; Inhibitory Concentration 50; Lithium; Luminescent Proteins; Plasmids; Promoter Regions, Genetic; Proto-Oncogene Proteins; Recombinant Fusion Proteins; Signal Transduction; Teratogens; Time Factors; Transcription, Genetic; Transfection; Valproic Acid; Wnt Proteins; Xenopus; Zebrafish Proteins | 2001 |
Does EEG predict response to valproate versus lithium in patients with mania?
Topics: Acute Disease; Adult; Anticonvulsants; Antimanic Agents; Bipolar Disorder; Brain; Electroencephalography; Female; Humans; Lithium; Male; Middle Aged; Psychotic Disorders; Severity of Illness Index; Valproic Acid | 2001 |
[Manic syndrome: diagnostic trends and principles of treatment].
Topics: Adult; Anticonvulsants; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Carbamazepine; Chlorpromazine; Diagnosis, Differential; Haloperidol; Hospitalization; Humans; Iatrogenic Disease; Lithium; Neurocognitive Disorders; Schizophrenia; Syndrome; Time Factors; Valproic Acid | 1998 |
Consensus guidelines outline drug selection and sequencing options for bipolar disorder.
Topics: Antidepressive Agents; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Cyclohexanols; Depressive Disorder; Drug Therapy, Combination; Humans; Lithium; Practice Guidelines as Topic; Valproic Acid | 2000 |
Epi-inositol regulates expression of the yeast INO1 gene encoding inositol-1-P synthase.
Topics: Anticonvulsants; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Fungal; Inositol; Isomerism; Lithium; Myo-Inositol-1-Phosphate Synthase; Saccharomyces cerevisiae; Valproic Acid | 2002 |
Lithium protection against glutamate excitotoxicity in rat cerebral cortical neurons: involvement of NMDA receptor inhibition possibly by decreasing NR2B tyrosine phosphorylation.
Topics: Animals; Antimanic Agents; Calcium; Cells, Cultured; Cerebral Cortex; Cytoprotection; Dose-Response Relationship, Drug; Glutamic Acid; Ion Transport; Lithium; Neurons; Phosphorylation; Rats; Receptors, N-Methyl-D-Aspartate; Time Factors; Tyrosine; Valproic Acid | 2002 |
A common mechanism of action for three mood-stabilizing drugs.
Topics: Animals; Animals, Newborn; Antimanic Agents; Bipolar Disorder; Calcium-Calmodulin-Dependent Protein Kinases; Carbamazepine; Cell Aggregation; Chemotaxis; Dictyostelium; Ganglia, Spinal; Genes, Protozoan; Glycogen Synthase Kinases; Growth Cones; Histone Deacetylase Inhibitors; Histone Deacetylases; Hydroxamic Acids; Inositol 1,4,5-Trisphosphate; Lithium; Mice; Mutation; Neurons, Afferent; Rats; Signal Transduction; Valproic Acid | 2002 |
Nonadherence with mood stabilizers: prevalence and predictors.
Topics: Adult; Anticonvulsants; Antidepressive Agents; Attitude of Health Personnel; Attitude to Health; Bipolar Disorder; Carbamazepine; Cohort Studies; Denial, Psychological; Depressive Disorder; Drug Therapy, Combination; Female; Humans; Lithium; Logistic Models; Male; Patient Compliance; Physician-Patient Relations; Probability; Psychiatric Status Rating Scales; Severity of Illness Index; Valproic Acid | 2002 |
A retrospective comparison of weight, lipid, and glucose changes between risperidone- and olanzapine-treated inpatients: metabolic outcomes after 1 year.
Topics: Adult; Aged; Anticonvulsants; Antipsychotic Agents; Benzodiazepines; Blood Glucose; Body Weight; Diabetes Mellitus; Drug Therapy, Combination; Fasting; Female; Glucose Tolerance Test; Hospitalization; Humans; Hyperlipidemias; Lipid Metabolism; Lipids; Lithium; Male; Middle Aged; Olanzapine; Outcome Assessment, Health Care; Pirenzepine; Retrospective Studies; Risperidone; Schizophrenia; Valproic Acid | 2002 |
Valproate regulates GSK-3-mediated axonal remodeling and synapsin I clustering in developing neurons.
Topics: Animals; Animals, Newborn; Antimanic Agents; Axons; Brain; Calcium-Calmodulin-Dependent Protein Kinases; Cell Differentiation; Cells, Cultured; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Histone Deacetylase Inhibitors; Histone Deacetylases; Lithium; Mice; Microtubule-Associated Proteins; Microtubules; Nerve Fibers; Neuronal Plasticity; Proto-Oncogene Proteins; Signal Transduction; Synapsins; Valproic Acid; Wnt Proteins | 2002 |
Different dependence of lithium and valproate on PI3K/PKB pathway.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Animals; Animals, Newborn; Antimanic Agents; Apoptosis; Caspase Inhibitors; Caspases; Cells, Cultured; Ceramides; Cerebellum; Enzyme Activation; Enzyme Precursors; Lithium; Neurons; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Potassium; Protein Serine-Threonine Kinases; Rats; Rats, Wistar; Valproic Acid | 2002 |
Evaluation of neuroprotection by lithium and valproic acid against ouabain-induced cell damage.
Topics: Antimanic Agents; Apoptosis; DNA Fragmentation; Dose-Response Relationship, Drug; Humans; L-Lactate Dehydrogenase; Lithium; Neuroblastoma; Neurons; Neuroprotective Agents; Ouabain; Sodium-Potassium-Exchanging ATPase; Tumor Cells, Cultured; Valproic Acid | 2002 |
Drug treatment of conduct disorder in young people.
Topics: Adolescent; Adrenergic alpha-Agonists; Anticonvulsants; Antipsychotic Agents; Carbamazepine; Central Nervous System Stimulants; Child; Child Behavior Disorders; Child, Preschool; Clonidine; Conduct Disorder; Humans; Lithium; Randomized Controlled Trials as Topic; Valproic Acid | 2002 |
Treatment of bipolar disorder in older adults.
Topics: Aged; Anticonvulsants; Antidepressive Agents; Antipsychotic Agents; Bipolar Disorder; Carbamazepine; Humans; Lithium; Valproic Acid | 2002 |
Low glial numbers in the amygdala in major depressive disorder.
Topics: Amygdala; Anticonvulsants; Bipolar Disorder; Cell Count; Cell Size; Depressive Disorder, Major; Entorhinal Cortex; Humans; Lithium; Neuroglia; Neurons; Valproic Acid | 2002 |
Changes in body weight and body mass index among psychiatric patients receiving lithium, valproate, or topiramate: an open-label, nonrandomized chart review.
Topics: Adult; Anticonvulsants; Antimanic Agents; Body Mass Index; Body Weight; Data Collection; Female; Fructose; Humans; Lithium; Male; Medical Records; Psychotic Disorders; Topiramate; Valproic Acid | 2002 |
Can we conduct some large simple trials in bipolar disorder?
Topics: Anticonvulsants; Bipolar Disorder; Humans; Lithium; Randomized Controlled Trials as Topic; Research Design; Treatment Outcome; Valproic Acid | 2002 |
Expression of G-proteins and regulators of G-protein signalling in neutrophils of patients with bipolar disorder: effects of mood stabilizers.
Topics: Antimanic Agents; Bipolar Disorder; Case-Control Studies; GTP-Binding Protein alpha Subunits, Gs; Heterotrimeric GTP-Binding Proteins; Humans; Lithium; Neutrophils; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Valproic Acid | 2002 |
Lithium and valproate decrease the membrane phosphatidylinositol/phosphatidylcholine ratio.
Topics: Cell Membrane; Culture Media; Lithium; Phosphatidylcholines; Phosphatidylinositols; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Valproic Acid | 2003 |
Neuroprotective properties of valproate: potential benefit for AD and tauopathies.
Topics: Alzheimer Disease; Animals; Anticonvulsants; Clinical Trials as Topic; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Lithium; Mice; Neuroprotective Agents; Phosphorylation; Research Design; Tauopathies; Valproic Acid | 2002 |
Attenuation of N-methyl-D-aspartate-mediated cytoplasmic vacuolization in primary rat hippocampal neurons by mood stabilizers.
Topics: Animals; Antimanic Agents; Bipolar Disorder; Carbamazepine; Cell Survival; Cells, Cultured; Cytoplasm; Drug Interactions; Fetus; Glial Fibrillary Acidic Protein; Hippocampus; Lithium; Microscopy, Electron; N-Methylaspartate; Nerve Degeneration; Neurons; Neuroprotective Agents; Phosphopyruvate Hydratase; Rats; Treatment Outcome; Vacuoles; Valproic Acid | 2003 |
Chronic lithium and sodium valproate both decrease the concentration of myoinositol and increase the concentration of inositol monophosphates in rat brain.
Topics: Animals; Anticonvulsants; Brain Chemistry; Central Nervous System Stimulants; Creatine; Dextroamphetamine; Glucose-6-Phosphate; Glycine; Inositol; Inositol Phosphates; Lithium; Magnetic Resonance Spectroscopy; Male; Phosphocreatine; Phosphorylcholine; Rats; Rats, Sprague-Dawley; Valproic Acid | 2003 |
Valproic acid inhibits substance P-induced activation of protein kinase C epsilon and expression of the substance P receptor.
Topics: Animals; Anticonvulsants; Antimanic Agents; Carbamazepine; Cells, Cultured; Drug Stability; Enzyme Activation; Humans; Interleukin-6; Lithium; Protein Kinase C; Protein Kinase C-epsilon; Rats; Rats, Wistar; Receptors, Neurokinin-1; Substance P; Valproic Acid | 2003 |
Effects of chronic lithium and sodium valproate on concentrations of brain amino acids.
Topics: Alanine; Amino Acids; Analysis of Variance; Animals; Aspartic Acid; Brain; Brain Chemistry; Chromatography, High Pressure Liquid; Enzyme Inhibitors; gamma-Aminobutyric Acid; Glutamic Acid; Lithium; Magnetic Resonance Imaging; Male; Rats; Rats, Sprague-Dawley; Taurine; Valproic Acid | 2003 |
Lack of effect of mood stabilizers or neuroleptics on GSK-3 protein levels and GSK-3 activity.
Topics: Affect; Animals; Antimanic Agents; Antipsychotic Agents; Blotting, Western; Chlorpromazine; Clozapine; Frontal Lobe; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Haloperidol; Lithium; Rats; Rats, Sprague-Dawley; Valproic Acid | 2003 |
Adjunctive quetiapine in bipolar patients partially responsive to lithium or valproate.
Topics: Adult; Aged; Bipolar Disorder; Dibenzothiazepines; Drug Therapy, Combination; Female; Humans; Lithium; Male; Middle Aged; Quetiapine Fumarate; Retrospective Studies; Valproic Acid | 2003 |
Mood stabilizers in hospitalized children with bipolar disorder: a retrospective review.
Topics: Analysis of Variance; Anticonvulsants; Bipolar Disorder; Carbamazepine; Child; Child, Hospitalized; Female; Humans; Length of Stay; Lithium; Male; Retrospective Studies; Treatment Outcome; Valproic Acid | 2003 |
Convergent effects of lithium and valproate on the expression of proteins associated with large dense core vesicles in NGF-differentiated PC12 cells.
Topics: Animals; Anticonvulsants; Blotting, Northern; Blotting, Western; Carrier Proteins; Cell Differentiation; Chromosomal Proteins, Non-Histone; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Gene Expression Regulation; HSP40 Heat-Shock Proteins; Lithium; Membrane Glycoproteins; Membrane Proteins; Membrane Transport Proteins; Nerve Growth Factor; Nerve Tissue Proteins; Neuropeptides; PC12 Cells; Potassium Chloride; Rats; Secretory Vesicles; Synaptophysin; Time Factors; Tritium; Valproic Acid; Vesicular Acetylcholine Transport Proteins; Vesicular Biogenic Amine Transport Proteins; Vesicular Monoamine Transport Proteins; Vesicular Transport Proteins | 2004 |
[Fast control of manic or mixed episodes. Atypical neuroleptics for bipolar patients].
Topics: Acute Disease; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Clinical Trials as Topic; Dopamine Antagonists; Drug Therapy, Combination; Haloperidol; Humans; Isotopes; Lithium; Olanzapine; Pirenzepine; Selective Serotonin Reuptake Inhibitors; Time Factors; Valproic Acid | 2003 |
[Long-term therapy with intuition].
Topics: Acute Disease; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Clinical Trials as Topic; Drug Therapy, Combination; Hospitalization; Humans; Isotopes; Lithium; Olanzapine; Patient Readmission; Pirenzepine; Placebos; Recurrence; Selective Serotonin Reuptake Inhibitors; Time Factors; Valproic Acid | 2003 |
Structurally dissimilar antimanic agents modulate synaptic plasticity by regulating AMPA glutamate receptor subunit GluR1 synaptic expression.
Topics: Animals; Antimanic Agents; Biotin; Blotting, Western; Cells, Cultured; Down-Regulation; Lithium; Male; Neuronal Plasticity; Rats; Receptors, AMPA; Synapses; Synaptic Transmission; Synaptosomes; Valproic Acid | 2003 |
Lithium regulates total and synaptic expression of the AMPA glutamate receptor GluR2 in vitro and in vivo.
Topics: Animals; Antidepressive Agents; Antimanic Agents; Down-Regulation; Hippocampus; Imipramine; Immunohistochemistry; Lithium; Organ Culture Techniques; Rats; Rats, Inbred WKY; Receptors, AMPA; Receptors, Cell Surface; Synapses; Valproic Acid | 2003 |
Effects of lithium and valproate on agonist-induced platelet intracellular calcium mobilization: relevance to myosin light chain kinase.
Topics: Adult; Antimanic Agents; Azepines; Blood Platelets; Calcium; Enzyme Inhibitors; Humans; In Vitro Techniques; Lithium; Male; Myosin-Light-Chain Kinase; Pilot Projects; Serotonin; Thrombin; Valproic Acid | 2004 |
Clinical case presentation: therapeutic challenges in adolescent-onset bipolar disorder.
Topics: Adolescent; Aggression; Anti-Anxiety Agents; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Clonazepam; Diagnosis, Differential; Education; Family; GABA Modulators; Haloperidol; Hospitalization; Humans; Irritable Mood; Lithium; Lorazepam; Male; Piperazines; Psychiatric Status Rating Scales; Sexual Behavior; Thiazoles; Valproic Acid | 2003 |
Lithium the lifesaver.
Topics: Antimanic Agents; Bipolar Disorder; Humans; Lithium; Suicide; Suicide Prevention; Valproic Acid | 2004 |
Glutathione S-transferase is a novel target for mood stabilizing drugs in primary cultured neurons.
Topics: Animals; Antimanic Agents; Blotting, Northern; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression Profiling; Gene Expression Regulation; Glutathione Transferase; Isoenzymes; Lithium; Neurons; Oligonucleotide Array Sequence Analysis; Rats; RNA, Messenger; Valproic Acid | 2004 |
Cell-type specific regulation of calreticulin and Bcl-2 expression by mood stabilizer drugs.
Topics: Analysis of Variance; Animals; Antihypertensive Agents; Antimanic Agents; Calreticulin; Caprylates; Cell Line; Dose-Response Relationship, Drug; Gene Expression Regulation; Humans; Immunoblotting; Lithium; Neuroglia; Neurons; Proto-Oncogene Proteins c-bcl-2; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Valproic Acid | 2004 |
Case of bipolar disorder successfully stabilized with clonazepam, valproate and lithium after numerous relapses for 47 years.
Topics: Aged; Antimanic Agents; Bipolar Disorder; Clonazepam; Drug Resistance; Drug Therapy, Combination; Female; GABA Agents; GABA Modulators; Humans; Lithium; Psychiatric Status Rating Scales; Recurrence; Valproic Acid | 2004 |
Lithium, a common drug for bipolar disorder treatment, regulates amyloid-beta precursor protein processing.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Bipolar Disorder; Brain; Cells, Cultured; Enzyme Inhibitors; Genes, Dominant; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Lithium; Mice; Mice, Transgenic; Oligonucleotides, Antisense; Protein Processing, Post-Translational; Valproic Acid | 2004 |
Pharmaceutical drug overdose case reports. From the World Literature.
Topics: Acetaminophen; Adolescent; Adult; Aged; Amlodipine; Child, Preschool; Diphenhydramine; Dizocilpine Maleate; Drug Overdose; Female; Humans; International Normalized Ratio; Lithium; Male; Middle Aged; Paroxetine; Salicylates; Valproic Acid; Warfarin | 2003 |
Mood stabilizers inhibit glucocorticoid receptor function in LMCAT cells.
Topics: Amphetamine; Animals; Anthracenes; Antimanic Agents; Blotting, Western; Carbamazepine; Cell Line; Cell Survival; Chloramphenicol O-Acetyltransferase; Corticosterone; Dose-Response Relationship, Drug; Flavonoids; Gene Expression Regulation, Enzymologic; Imidazoles; Indoles; Inositol; Lithium; Maleimides; Protein Kinase C; Protein Kinase C-alpha; Pyridines; Receptors, Glucocorticoid; Tamoxifen; Tetradecanoylphorbol Acetate; Valproic Acid | 2004 |
Chart review of the impact of attention-deficit/hyperactivity disorder comorbidity on response to lithium or divalproex sodium in adolescent mania.
Topics: Adolescent; Adult; Anticonvulsants; Attention Deficit Disorder with Hyperactivity; Bipolar Disorder; Child; Comorbidity; Female; Humans; Lithium; Longitudinal Studies; Male; Medical Records; Psychiatric Status Rating Scales; Retrospective Studies; Treatment Outcome; Valproic Acid | 2004 |
A mood stabilizer with risperidone or haloperidol for mania.
Topics: Anticonvulsants; Antipsychotic Agents; Bipolar Disorder; Double-Blind Method; Drug Therapy, Combination; Ethics, Research; Haloperidol; Humans; Lithium; Patient Selection; Placebos; Randomized Controlled Trials as Topic; Research Design; Risperidone; Valproic Acid | 2004 |
Pharmacokinetics of aripiprazole and concomitant lithium and valproate.
Topics: Adult; Aripiprazole; Drug Therapy, Combination; Humans; Lithium; Male; Middle Aged; Piperazines; Psychotic Disorders; Quinolones; Schizophrenia; Valproic Acid | 2005 |
Protracted lithium treatment protects against the ER stress elicited by thapsigargin in rat PC12 cells: roles of intracellular calcium, GRP78 and Bcl-2.
Topics: Animals; Blotting, Western; Calcium; Calcium-Transporting ATPases; Cell Survival; Curcumin; Electrophoretic Mobility Shift Assay; Endoplasmic Reticulum; Enzyme Inhibitors; Heat-Shock Proteins; Lithium; Molecular Chaperones; Neuroprotective Agents; PC12 Cells; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-fos; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thapsigargin; Transcription Factor AP-1; Valproic Acid | 2005 |
Hypoxia activates glycogen synthase kinase-3 in mouse brain in vivo: protection by mood stabilizers and imipramine.
Topics: Animals; Anticonvulsants; Antidepressive Agents, Tricyclic; Brain; Carbon Dioxide; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Activation; Glycogen Synthase Kinase 3; Hypoxia; Imipramine; Immunoblotting; Immunohistochemistry; Lithium; Male; Mice; Mice, Inbred C57BL; Nitrogen; Phosphorylation; Serine; Time Factors; Valproic Acid | 2005 |
Opposite effects of lithium and valproic acid on trophic factor deprivation-induced glycogen synthase kinase-3 activation, c-Jun expression and neuronal cell death.
Topics: Animals; Cell Death; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Glycogen Synthase Kinase 3; Lithium; Nerve Growth Factors; Neurons; Proto-Oncogene Proteins c-jun; Rats; Rats, Sprague-Dawley; Valproic Acid | 2005 |
Drug treatments for bipolar disorder: 1--Acute manic or depressive episodes.
Topics: Adult; Anticonvulsants; Antidepressive Agents; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Carbamazepine; Depressive Disorder; Humans; Lithium; Randomized Controlled Trials as Topic; Valproic Acid | 2005 |
The anti-apoptotic, glucocorticoid receptor cochaperone protein BAG-1 is a long-term target for the actions of mood stabilizers.
Topics: Alkaline Phosphatase; Animals; Antimanic Agents; Behavior, Animal; Blotting, Western; Cell Line, Tumor; Dexamethasone; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Interactions; Gene Expression; Hippocampus; Humans; Immunohistochemistry; Indoles; Lithium; Male; Molecular Weight; Neuroblastoma; Rats; Rats, Wistar; Receptors, Glucocorticoid; RNA, Small Interfering; Time Factors; Transcription Factors; Transfection; Valproic Acid | 2005 |
GSK-3 activity in neocortical cells is inhibited by lithium but not carbamazepine or valproic acid.
Topics: Animals; Antimanic Agents; Carbamazepine; Cells, Cultured; Glycogen Synthase Kinase 3; Isoenzymes; Lithium; Neurons; Rats; Valproic Acid | 2005 |
Lithium- and valproate-induced alterations in circadian locomotor behavior in Drosophila.
Topics: Animals; Antimanic Agents; Circadian Rhythm; Dose-Response Relationship, Drug; Drosophila; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Lithium; Motor Activity; Valproic Acid | 2005 |
Chronic treatment with mood stabilizers lithium and valproate prevents excitotoxicity by inhibiting oxidative stress in rat cerebral cortical cells.
Topics: Animals; Antimanic Agents; Calcium; Cell Survival; Cells, Cultured; Cerebral Cortex; Excitatory Amino Acids; Glutamic Acid; In Situ Nick-End Labeling; Lipid Peroxidation; Lithium; Nerve Tissue Proteins; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Sprague-Dawley; Valproic Acid | 2005 |
Apoptosis-associated tyrosine kinase (AATYK) has differential Ca2+-dependent phosphorylation states in response to survival and apoptotic conditions in cerebellar granule cells.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Blotting, Western; Calcium; Calcium Channels; Cell Movement; Cell Survival; Cells, Cultured; Cerebellum; Dose-Response Relationship, Drug; Enzyme Inhibitors; Lithium; Mice; Mutation; Phosphorylation; Plasmids; Potassium; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-jun; Serine; Valproic Acid | 2005 |
An investigation of the efficacy of mood stabilizers in rodent models of prepulse inhibition.
Topics: Amphetamine; Anesthetics, Dissociative; Animals; Antimanic Agents; Carbamazepine; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Drug Interactions; Ketamine; Lithium; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Phenytoin; Reflex, Startle; Valproic Acid | 2005 |
Cingulate cortex anatomical abnormalities in children and adolescents with bipolar disorder.
Topics: Adolescent; Adult; Age Factors; Anticonvulsants; Atrophy; Bipolar Disorder; Brain; Brain Mapping; Child; Female; Functional Laterality; Gyrus Cinguli; Humans; Image Processing, Computer-Assisted; Lithium; Magnetic Resonance Imaging; Male; Sex Factors; Valproic Acid | 2005 |
Genetic perturbation of glycolysis results in inhibition of de novo inositol biosynthesis.
Topics: Amino Acid Sequence; Base Sequence; DNA Primers; Glycolysis; Inositol; Lithium; Molecular Sequence Data; Mutation; Saccharomyces cerevisiae; Sequence Homology, Amino Acid; Triose-Phosphate Isomerase; Valproic Acid | 2005 |
A positron emission tomography study of the effects of treatment with valproate on brain 5-HT2A receptors in acute mania.
Topics: Acute Disease; Adult; Antimanic Agents; Bipolar Disorder; Brain; Contrast Media; Female; Humans; Lithium; Male; Middle Aged; Positron-Emission Tomography; Pyrimidinones; Receptor, Serotonin, 5-HT2A; Valproic Acid | 2005 |
In Saccharomyces cerevisiae, impaired PRPP synthesis is accompanied by valproate and Li+ sensitivity.
Topics: Binding Sites; Cell Wall; Lithium; Phospholipids; Phosphoribosyl Pyrophosphate; Ribose-Phosphate Pyrophosphokinase; Saccharomyces cerevisiae; Valproic Acid | 2005 |
Reliability and validity of the pathological gambling adaptation of the Yale-Brown Obsessive-Compulsive Scale (PG-YBOCS).
Topics: Adult; Disruptive, Impulse Control, and Conduct Disorders; Female; Fluvoxamine; Gambling; Humans; Lithium; Male; Obsessive-Compulsive Disorder; Psychometrics; Reproducibility of Results; Sensitivity and Specificity; Severity of Illness Index; Surveys and Questionnaires; Valproic Acid | 2005 |
Suicidal ideation and pharmacotherapy among STEP-BD patients.
Topics: Adult; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antimanic Agents; Bipolar Disorder; Cohort Studies; Female; Humans; Lithium; Logistic Models; Male; Patient Care Planning; Suicide; Suicide Prevention; United States; Valproic Acid | 2005 |
Adjunctive lamotrigine as a possible mania inducer in bipolar patients.
Topics: Adult; Antidepressive Agents; Antipsychotic Agents; Bipolar Disorder; Dibenzothiazepines; Drug Therapy, Combination; Female; Humans; Lamotrigine; Lithium; Male; Quetiapine Fumarate; Triazines; Valproic Acid | 2006 |
What is bipolar disorder?
Topics: Bipolar Disorder; Disease Susceptibility; Frontal Lobe; Humans; Lithium; Recurrence; Regional Blood Flow; Research Design; Treatment Outcome; Valproic Acid | 2006 |
Risk and resilience markers in bipolar disorder: brain responses to emotional challenge in bipolar patients and their healthy siblings.
Topics: Adult; Biomarkers; Bipolar Disorder; Brain; Cohort Studies; Depressive Disorder; Emotions; Female; Frontal Lobe; Gyrus Cinguli; Humans; Lithium; Male; Oxygen Radioisotopes; Positron-Emission Tomography; Regional Blood Flow; Risk Factors; Siblings; Temporal Lobe; Valproic Acid; Water | 2006 |
Effects of mood stabilizers on hippocampus BDNF levels in an animal model of mania.
Topics: Affect; Amphetamine; Animals; Antimanic Agents; Bipolar Disorder; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Hippocampus; Lithium; Male; Rats; Rats, Wistar; Valproic Acid | 2006 |
Behavioral effects of short-term administration of lithium and valproic acid in rats.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Dose-Response Relationship, Drug; Lithium; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Self Stimulation; Time Factors; Valproic Acid | 2006 |
Sustained attention deficits in manic and euthymic patients with bipolar disorder.
Topics: Adult; Anticonvulsants; Antimanic Agents; Arousal; Attention Deficit Disorder with Hyperactivity; Bipolar Disorder; Carbamazepine; Female; Humans; Lithium; Male; Neuropsychological Tests; Psychiatric Status Rating Scales; Psychomotor Performance; Reaction Time; Valproic Acid | 2006 |
Lithium increases nerve growth factor levels in the rat hippocampus in an animal model of mania.
Topics: Amphetamine; Animals; Antimanic Agents; Bipolar Disorder; Central Nervous System Stimulants; Hippocampus; Lithium; Male; Motor Activity; Nerve Growth Factors; Rats; Rats, Wistar; Valproic Acid | 2006 |
Role of glutathione in neuroprotective effects of mood stabilizing drugs lithium and valproate.
Topics: Animals; Antimanic Agents; Brain; Carbamazepine; Cell Death; Cell Line, Tumor; Cells, Cultured; Cerebral Cortex; Enzyme Inhibitors; Glutamate-Cysteine Ligase; Glutathione; Humans; Lamotrigine; Lithium; Nerve Degeneration; Neurons; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Triazines; Valproic Acid | 2007 |
Synergistic neuroprotective effects of lithium and valproic acid or other histone deacetylase inhibitors in neurons: roles of glycogen synthase kinase-3 inhibition.
Topics: Animals; Animals, Newborn; Cells, Cultured; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Histone Deacetylase Inhibitors; Histone Deacetylases; Lithium; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Valproic Acid | 2008 |
Use of hemodialysis and hemoperfusion in poisoned patients.
Topics: Acetaminophen; Carbamazepine; Ethylene Glycol; Hemoperfusion; Humans; Lithium; Poisoning; Poisons; Renal Dialysis; Retrospective Studies; Sorption Detoxification; Valproic Acid | 2008 |
GSK3beta modulates PACAP-induced neuritogenesis in PC12 cells by acting downstream of Rap1 in a caveolae-dependent manner.
Topics: Animals; Caveolae; Caveolin 1; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Lithium; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 3; Neurites; PC12 Cells; Phosphorylation; Pituitary Adenylate Cyclase-Activating Polypeptide; rap1 GTP-Binding Proteins; Rats; RNA, Small Interfering; Signal Transduction; Time Factors; Valproic Acid | 2009 |
Valproate, a mood stabilizer, induces WFS1 expression and modulates its interaction with ER stress protein GRP94.
Topics: Animals; Antimanic Agents; Biomarkers; Bipolar Disorder; Cell Line; Endoplasmic Reticulum; Gene Expression Regulation; Humans; Lithium; Membrane Glycoproteins; Membrane Proteins; Mice; Promoter Regions, Genetic; Stress, Physiological; Valproic Acid | 2009 |
Common effects of lithium and valproate on mitochondrial functions: protection against methamphetamine-induced mitochondrial damage.
Topics: Aldehydes; Analysis of Variance; Animals; Antimanic Agents; bcl-2-Associated X Protein; Brain; Cell Line, Tumor; Central Nervous System Stimulants; Cytochromes c; Dose-Response Relationship, Drug; Drug Interactions; Electron Transport Complex IV; Gene Expression Regulation; Humans; Lithium; Male; Methamphetamine; Mitochondria; Neuroblastoma; Oligonucleotide Array Sequence Analysis; Organic Chemicals; Oxygen Consumption; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-jun; Rats; Rats, Inbred WKY; RNA, Small Interfering; Time Factors; Transfection; Tyrosine 3-Monooxygenase; Valproic Acid | 2009 |
Inhibition of specific adenylyl cyclase isoforms by lithium and carbamazepine, but not valproate, may be related to their antidepressant effect.
Topics: Adenylyl Cyclases; Amphetamine; Analysis of Variance; Animals; Antimanic Agents; Benzazepines; Carbamazepine; Chlorocebus aethiops; Colforsin; COS Cells; Cyclic AMP; Dopamine Agonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Gene Expression Regulation; Isoenzymes; Lithium; Mice; Mice, Knockout; Models, Molecular; Motor Activity; Rotarod Performance Test; Swimming; Transfection; Valproic Acid | 2009 |
Effect of mood stabilizers on gene expression in lymphoblastoid cells.
Topics: Adult; Antimanic Agents; Cells, Cultured; Gene Expression; Humans; Lithium; Lymphocytes; Male; Middle Aged; Oligonucleotide Array Sequence Analysis; Reverse Transcriptase Polymerase Chain Reaction; Valproic Acid; Vascular Endothelial Growth Factor A | 2010 |
The mood stabilizers valproic acid and lithium enhance mesenchymal stem cell migration via distinct mechanisms.
Topics: Affect; Animals; Cell Movement; Cell Survival; Cells, Cultured; Drug Therapy, Combination; Gene Knockdown Techniques; Lithium; Matrix Metalloproteinase 9; Mesenchymal Stem Cells; Rats; Receptors, CXCR4; Valproic Acid | 2010 |
Inhibition of monoamine oxidase activity by antidepressants and mood stabilizers.
Topics: Affect; Amitriptyline; Animals; Antidepressive Agents; Antimanic Agents; Benzodiazepines; Cerebral Cortex; Citalopram; Clorgyline; Cocaine; Cyclohexanols; Desipramine; Fluoxetine; Imipramine; In Vitro Techniques; Iproniazid; Lithium; Mianserin; Mirtazapine; Mitochondria; Moclobemide; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Morpholines; Olanzapine; Pargyline; Reboxetine; Swine; Thiazepines; Valproic Acid; Venlafaxine Hydrochloride | 2010 |
Combined treatment with the mood stabilizers lithium and valproate produces multiple beneficial effects in transgenic mouse models of Huntington's disease.
Topics: Affect; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Huntington Disease; Lithium; Male; Mice; Mice, Transgenic; Valproic Acid | 2011 |
Treating mouse models of Huntington disease.
Topics: Affect; Animals; Female; Huntington Disease; Lithium; Male; Valproic Acid | 2011 |
Mesenchymal stem cells primed with valproate and lithium robustly migrate to infarcted regions and facilitate recovery in a stroke model.
Topics: Animals; Cell Movement; Infarction, Middle Cerebral Artery; Lithium; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Rats; Recovery of Function; Stroke; Valproic Acid | 2011 |
The effects of chronic treatment with mood stabilizers on the rat hippocampal post-synaptic density proteome.
Topics: Animals; Antipsychotic Agents; Drug Administration Schedule; Gene Regulatory Networks; Hippocampus; Lithium; Male; Mood Disorders; Post-Synaptic Density; Proteome; Rats; Rats, Inbred WKY; Treatment Outcome; Valproic Acid | 2011 |
Hard outcomes: clinical trials to reduce suicide.
Topics: Antimanic Agents; Bipolar Disorder; Female; Humans; Lithium; Male; Suicide Prevention; Suicide, Attempted; Valproic Acid | 2011 |
The effects of neuropsychiatric drugs on glycogen synthase kinase-3 signaling.
Topics: Animals; Antidepressive Agents; Antimanic Agents; Antipsychotic Agents; beta Catenin; Blotting, Western; Brain; Clozapine; Fluoxetine; Glycogen Synthase Kinase 3; Haloperidol; Imipramine; Immunoprecipitation; Lithium; Male; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Signal Transduction; Valproic Acid | 2011 |
Predictors of relapse or recurrence in bipolar I disorder.
Topics: Adolescent; Adult; Aged; Antimanic Agents; Benzodiazepines; Bipolar Disorder; Clinical Trials as Topic; Double-Blind Method; Female; Follow-Up Studies; Humans; Lithium; Male; Middle Aged; Olanzapine; Prognosis; Recurrence; Valproic Acid | 2012 |
Valproic acid phase shifts the rhythmic expression of Period2::Luciferase.
Topics: Animals; Anticonvulsants; Cells, Cultured; Circadian Rhythm; Female; Fibroblasts; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Lithium; Luciferases; Luminescent Measurements; Mice; Mice, Transgenic; Period Circadian Proteins; Recombinant Fusion Proteins; Suprachiasmatic Nucleus; Valproic Acid | 2011 |
Additional effect size measures helpful in understanding lithium and valproate trial results.
Topics: Antimanic Agents; Bipolar Disorder; Female; Humans; Lithium; Male; Suicide Prevention; Suicide, Attempted; Valproic Acid | 2012 |
Differential lithium efficacy in reducing suicidal behaviors compared with suicidal thoughts.
Topics: Antimanic Agents; Bipolar Disorder; Female; Humans; Lithium; Male; Suicide Prevention; Suicide, Attempted; Valproic Acid | 2012 |
Lithium and valproate prevent olfactory discrimination and short-term memory impairments in the intranasal 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) rat model of Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Administration, Intranasal; Age Factors; Animals; Animals, Newborn; Avoidance Learning; Chromatography, High Pressure Liquid; Discrimination, Psychological; Disease Models, Animal; Dopamine; Drug Administration Schedule; Drug Interactions; Exploratory Behavior; Lithium; Male; Memory Disorders; Memory, Short-Term; Neuroprotective Agents; Neurotoxins; Olfaction Disorders; Parkinsonian Disorders; Rats; Rats, Wistar; Recognition, Psychology; Serotonin; Statistics, Nonparametric; Swimming; Valproic Acid | 2012 |
The combination of valproic acid and lithium delays hematopoietic stem/progenitor cell differentiation.
Topics: Animals; Cell Differentiation; Cells, Cultured; Drug Combinations; Drug Evaluation, Preclinical; Drug Interactions; Female; Hematopoiesis; Hematopoietic Stem Cells; Lithium; Mice; Mice, Inbred C57BL; Myeloid Cells; Phenotype; Time Factors; Valproic Acid | 2012 |
Persistent febrile illness with multisystem organ failure associated with clozapine.
Topics: Abdominal Pain; Adult; Antipsychotic Agents; Clozapine; Combined Modality Therapy; Diagnostic Errors; Dibenzothiazepines; Drug Therapy, Combination; Female; Fever; Fluid Therapy; Headache; Hemodiafiltration; Humans; Lithium; Multiple Organ Failure; Norepinephrine; Quetiapine Fumarate; Schizophrenia; Systemic Inflammatory Response Syndrome; Urinary Tract Infections; Valproic Acid; Vasoconstrictor Agents | 2012 |
Mood stabilizers commonly restore staurosporine-induced increase of p53 expression and following decrease of Bcl-2 expression in SH-SY5Y cells.
Topics: Antimanic Agents; Apoptosis; Carbamazepine; Cell Line, Tumor; Enzyme Inhibitors; Gene Expression; Humans; Lamotrigine; Lithium; Neurons; Proto-Oncogene Proteins c-bcl-2; Staurosporine; Triazines; Tumor Suppressor Protein p53; Valproic Acid | 2012 |
Carbamazepine treatment of bipolar disorder: a retrospective evaluation of naturalistic long-term outcomes.
Topics: Adult; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Carbamazepine; Female; Humans; Lithium; Male; Middle Aged; Retrospective Studies; Treatment Outcome; Valproic Acid | 2012 |
Management of cluster headache.
Topics: Analgesics; Cluster Headache; Deep Brain Stimulation; Disease Management; Ergotamine; Fructose; Humans; Hypothalamus; Lithium; Methysergide; Oxygen; Prevalence; Randomized Controlled Trials as Topic; Sumatriptan; Topiramate; Valproic Acid; Verapamil | 2012 |
[Unipolar mania: a distinct entity or characteristic of manic preponderance?].
Topics: Anticonvulsants; Bipolar Disorder; Diagnostic and Statistical Manual of Mental Disorders; Humans; Lithium; Psychiatric Status Rating Scales; Treatment Outcome; Valproic Acid | 2012 |
Evaluation of behavioral and neurochemical changes induced by ketamine in rats: implications as an animal model of mania.
Topics: Animals; Antimanic Agents; Behavior, Animal; Bipolar Disorder; Disease Models, Animal; Drug Interactions; Ketamine; Lithium; Male; Protein Carbonylation; Rats; Rats, Wistar; Valproic Acid | 2012 |
New model of action for mood stabilizers: phosphoproteome from rat pre-frontal cortex synaptoneurosomal preparations.
Topics: Actins; Affect; Animals; Antipsychotic Agents; Cell Line, Tumor; Isoxazoles; Lithium; Male; Mitochondria; Paliperidone Palmitate; Phosphoproteins; Prefrontal Cortex; Proteome; Pyrimidines; Rats; Rats, Sprague-Dawley; Synapses; Synaptosomes; Time Factors; Tubulin; Valproic Acid | 2013 |
Posttrauma cotreatment with lithium and valproate: reduction of lesion volume, attenuation of blood-brain barrier disruption, and improvement in motor coordination in mice with traumatic brain injury.
Topics: Animals; Antimanic Agents; Blood-Brain Barrier; Brain Injuries; Disease Models, Animal; Drug Therapy, Combination; Lithium; Male; Mice; Mice, Inbred C57BL; Movement Disorders; Valproic Acid | 2013 |
Mechanisms for L-channel-mediated increase in [Ca(2+)]i and its reduction by anti-bipolar drugs in cultured astrocytes combined with its mRNA expression in freshly isolated cells support the importance of astrocytic L-channels.
Topics: Animals; Astrocytes; Brain; Calcium; Calcium Channels, L-Type; Carbamazepine; Cells, Cultured; Central Nervous System Depressants; Down-Regulation; Female; Ions; Lithium; Male; Mice; Mice, Transgenic; Nifedipine; Potassium; RNA, Messenger; Ryanodine; Ryanodine Receptor Calcium Release Channel; TRPC Cation Channels; Valproic Acid | 2013 |
Teaching neuroimages: reversible paradoxical lithium neurotoxicity.
Topics: Adult; Antimanic Agents; Bipolar Disorder; Gadolinium; Humans; Lithium; Magnetic Resonance Imaging; Male; Neuroimaging; Neurology; Neurotoxicity Syndromes; Treatment Outcome; Valproic Acid | 2013 |
Fenproporex increases locomotor activity and alters energy metabolism, and mood stabilizers reverse these changes: a proposal for a new animal model of mania.
Topics: Amphetamines; Animals; Antimanic Agents; Bipolar Disorder; Disease Models, Animal; Dose-Response Relationship, Drug; Energy Metabolism; Lithium; Male; Motor Activity; Rats; Rats, Wistar; Valproic Acid | 2014 |
SHANK3 overexpression causes manic-like behaviour with unique pharmacogenetic properties.
Topics: Actin-Related Protein 2-3 Complex; Actins; Adult; Animals; Behavior, Animal; Bipolar Disorder; Chromosomes, Human, Pair 22; Disease Models, Animal; Excitatory Postsynaptic Potentials; Female; Gene Dosage; Gene Expression; Genes, Duplicate; Humans; Hyperkinesis; Inhibitory Postsynaptic Potentials; Lithium; Male; Mice; Mice, Transgenic; Microfilament Proteins; Nerve Tissue Proteins; Seizures; Valproic Acid | 2013 |
FGF-21, a novel metabolic regulator, has a robust neuroprotective role and is markedly elevated in neurons by mood stabilizers.
Topics: Animals; Animals, Newborn; Antimanic Agents; Cells, Cultured; Cerebral Cortex; Drug Synergism; Excitatory Amino Acid Agonists; Fibroblast Growth Factors; Gene Expression Regulation; Glutamic Acid; Glycogen Synthase Kinase 3; Hippocampus; Lithium; Male; Mice; Neurons; Neuroprotective Agents; Oncogene Protein v-akt; Rats; Rats, Sprague-Dawley; Transduction, Genetic; Valproic Acid | 2015 |
Lithium use for bipolar disorder post renal transplant: is mood stabilization without toxicity possible?
Topics: Biopsy; Bipolar Disorder; Cyclosporine; Female; Glomerular Filtration Rate; Humans; Kidney Transplantation; Lithium; Middle Aged; Nephritis, Interstitial; Renal Insufficiency; Risk; Risperidone; Tacrolimus; Treatment Outcome; Valproic Acid | 2014 |
Chronic treatment with mood-stabilizers attenuates abnormal hyperlocomotion of GluA1-subunit deficient mice.
Topics: Animals; Anticonvulsants; Antipsychotic Agents; Behavior, Animal; Female; Hyperkinesis; Lithium; Male; Maze Learning; Mice; Mice, Knockout; Motor Activity; Receptors, AMPA; Valproic Acid | 2014 |
Lithium/Valproic acid combination and L-glutamate induce similar pattern of changes in the expression of miR-30a-5p in SH-SY5Y neuroblastoma cells.
Topics: Brain-Derived Neurotrophic Factor; Cell Line, Tumor; Drug Synergism; Gene Expression Regulation; Glutamic Acid; Humans; In Vitro Techniques; Lithium; MicroRNAs; Nerve Degeneration; Neuroblastoma; Neurons; Neuroprotective Agents; Neurotoxins; Real-Time Polymerase Chain Reaction; Up-Regulation; Valproic Acid | 2014 |
Histone deacetylase inhibitors reverse manic-like behaviors and protect the rat brain from energetic metabolic alterations induced by ouabain.
Topics: Animals; Antimanic Agents; Behavior, Animal; Bipolar Disorder; Brain; Butyric Acid; Citric Acid Cycle; Disease Models, Animal; Energy Metabolism; Exploratory Behavior; Histone Deacetylase Inhibitors; Lithium; Male; Motor Activity; Ouabain; Rats; Rats, Wistar; Valproic Acid | 2015 |
Phosphorylation of transcription factor specificity protein 4 is increased in peripheral blood mononuclear cells of first-episode psychosis.
Topics: Adolescent; Adult; Animals; Antipsychotic Agents; Benzodiazepines; Cells, Cultured; Cross-Sectional Studies; Female; Humans; Lithium; Male; Models, Biological; Neurons; Olanzapine; Phosphorylation; Pilot Projects; Psychotic Disorders; Rats; Serine; Sp4 Transcription Factor; Valproic Acid; Young Adult | 2015 |
Mortality associated with lithium and valproate treatment of US Veterans Health Administration patients with mental disorders.
Topics: Aged; Aged, 80 and over; Antimanic Agents; Antipsychotic Agents; Cohort Studies; Female; Humans; Lithium; Male; Mental Disorders; Mental Health; Regression Analysis; Risk Factors; Valproic Acid; Veterans Health | 2015 |
Changes in mood stabilizer prescription patterns in bipolar disorder.
Topics: Adult; Aged; Anticonvulsants; Antidepressive Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Drug Prescriptions; Female; Humans; Lithium; Male; Middle Aged; Olanzapine; Sweden; Valproic Acid | 2016 |
The rapid suicide protection of mood stabilizers on patients with bipolar disorder: A nationwide observational cohort study in Taiwan.
Topics: Adolescent; Adult; Aged; Antimanic Agents; Bipolar Disorder; Carbamazepine; Cohort Studies; Female; Humans; Lithium; Male; Middle Aged; Proportional Hazards Models; Suicide; Suicide Prevention; Taiwan; Valproic Acid; Young Adult | 2016 |
Omega-3 Fatty Acids and Mood Stabilizers Alter Behavioural and Energy Metabolism Parameters in Animals Subjected to an Animal Model of Mania Induced by Fenproporex.
Topics: Amphetamines; Animals; Antimanic Agents; Behavior, Animal; Bipolar Disorder; Citrate (si)-Synthase; Creatine Kinase; Disease Models, Animal; Energy Metabolism; Fatty Acids, Omega-3; Gene Expression Regulation; Lithium; Male; Rats, Wistar; Succinate Dehydrogenase; Valproic Acid | 2017 |
Human Pluripotent Stem Cell-derived Cortical Neurons for High Throughput Medication Screening in Autism: A Proof of Concept Study in SHANK3 Haploinsufficiency Syndrome.
Topics: Autism Spectrum Disorder; Cell Differentiation; Cells, Cultured; Haploinsufficiency; Human Embryonic Stem Cells; Humans; Lithium; Male; Nerve Tissue Proteins; Neuronal Plasticity; Neurons; Phenotype; Pluripotent Stem Cells; RNA, Messenger; Severity of Illness Index; Transcriptome; Valproic Acid | 2016 |
Lithium and valproate prevent methylphenidate-induced mania-like behaviors in the hole board test.
Topics: Animals; Antimanic Agents; Behavior, Animal; Bipolar Disorder; Central Nervous System Stimulants; Disease Models, Animal; Exploratory Behavior; Lithium; Locomotion; Male; Methylphenidate; Mice; Neuropsychological Tests; Valproic Acid | 2016 |
A population-based study of the comparative effectiveness of second-generation antipsychotics vs older antimanic agents in bipolar disorder.
Topics: Adult; Antidepressive Agents; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Cohort Studies; Comparative Effectiveness Research; Drug Therapy, Combination; Female; Hospitalization; Humans; Lithium; Male; Medication Therapy Management; Middle Aged; Outpatients; Psychiatric Status Rating Scales; United States; Valproic Acid | 2016 |
Current psychotropic medication prescribing patterns in late-life bipolar disorder.
Topics: Age of Onset; Aged; Aged, 80 and over; Antidepressive Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Cross-Sectional Studies; Drug Prescriptions; Drug Therapy, Combination; Female; Humans; Lithium; Male; Ontario; Practice Patterns, Physicians'; Prevalence; Psychotropic Drugs; Valproic Acid | 2017 |
Antipsychotic adjunctive therapy to mood stabilizers and 1-year rehospitalization rates in bipolar disorder: A cohort study.
Topics: Adult; Affect; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Cohort Studies; Drug Therapy, Combination; Female; Humans; Israel; Lithium; Male; Outcome and Process Assessment, Health Care; Patient Readmission; Retrospective Studies; Secondary Prevention; Valproic Acid | 2016 |
Protection against hormone-mediated mood symptoms.
Topics: Affect; Antipsychotic Agents; Bipolar Disorder; Female; Humans; Lithium; Lurasidone Hydrochloride; Menstrual Cycle; Premenstrual Syndrome; Psychotic Disorders; Treatment Outcome; Valproic Acid; Young Adult | 2017 |
Downregulation of Homer1b/c in SOD1 G93A Models of ALS: A Novel Mechanism of Neuroprotective Effect of Lithium and Valproic Acid.
Topics: Amyotrophic Lateral Sclerosis; Animals; Apoptosis; Cell Line; Genetic Predisposition to Disease; Homer Scaffolding Proteins; Humans; Lithium; Mice; Mice, Transgenic; Proto-Oncogene Proteins c-bcl-2; RNA Interference; RNA, Small Interfering; Superoxide Dismutase; Valproic Acid | 2016 |
Treatment of refractory psychogenic polydipsia with lithium.
Topics: Antipsychotic Agents; Enzyme Inhibitors; Humans; Hyponatremia; Lithium; Male; Polydipsia, Psychogenic; Risperidone; Seizures; Valproic Acid; Water Intoxication | 2017 |
Antimanic activity of minocycline in a GBR12909-induced model of mania in mice: Possible role of antioxidant and neurotrophic mechanisms.
Topics: Animals; Antimanic Agents; Antioxidants; Bipolar Disorder; Brain; Disease Models, Animal; Hippocampus; Lipid Peroxidation; Lithium; Male; Mice; Minocycline; Valproic Acid | 2018 |
Serotonin syndrome in patients with headache disorders.
Topics: Acetaminophen; Adult; Amitriptyline; Analgesics; Cluster Headache; Drug Therapy, Combination; Flunarizine; Humans; Lithium; Male; Middle Aged; Migraine Disorders; Serotonin Agents; Serotonin Syndrome; Tramadol; Valproic Acid | 2017 |
Genetic disruption of ankyrin-G in adult mouse forebrain causes cortical synapse alteration and behavior reminiscent of bipolar disorder.
Topics: Animals; Ankyrins; Bipolar Disorder; Disease Models, Animal; GABAergic Neurons; Lithium; Methylphenidate; Mice; Mice, Inbred C57BL; Mice, Knockout; Potassium Channels, Voltage-Gated; Prosencephalon; Proto-Oncogene Proteins c-fyn; Synapses; Valproic Acid; Voltage-Gated Sodium Channels | 2017 |
Associations between use of mood stabilizers and risk of cataract: A population-based nested case-control study.
Topics: Adult; Aged; Antimanic Agents; Bipolar Disorder; Carbamazepine; Case-Control Studies; Cataract; Databases, Factual; Female; Humans; Lamotrigine; Lithium; Male; Middle Aged; Risk; Schizophrenia; Taiwan; Triazines; Valproic Acid | 2018 |
Long-term use of valproic acid and the prevalence of cancers in bipolar disorder patients in a Taiwanese population: An association analysis using the National Health Insurance Research Database (NHIRD).
Topics: Adult; Aged; Anticonvulsants; Bipolar Disorder; Databases, Factual; Female; Humans; Incidence; Lithium; Male; Middle Aged; National Health Programs; Neoplasms; Prevalence; Proportional Hazards Models; Retrospective Studies; Risk Factors; Taiwan; Valproic Acid | 2018 |
Second-generation antipsychotic and diabetes mellitus in children and adolescents.
Topics: Adolescent; Antipsychotic Agents; Autistic Disorder; Benzodiazepines; Blood Glucose; Clomipramine; Diabetes Mellitus, Type 1; Humans; Hypoglycemic Agents; Insulin; Lithium; Male; Metformin; Olanzapine; Valproic Acid | 2017 |
Inhibition of the dopamine transporter as an animal model of bipolar disorder mania: Locomotor response, neuroimmunological profile and pharmacological modulation.
Topics: Animals; Antidepressive Agents; Aripiprazole; Bipolar Disorder; Brain; Cytokines; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Lithium; Locomotion; Male; Mice; Nerve Growth Factors; Piperazines; Time Factors; Valproic Acid | 2018 |
Abnormal brain activation during emotion processing of euthymic bipolar patients taking different mood stabilizers.
Topics: Adult; Amygdala; Bipolar Disorder; Brain; Brain Mapping; Cross-Sectional Studies; Emotions; Facial Expression; Female; Functional Laterality; Gyrus Cinguli; Humans; Lithium; Magnetic Resonance Imaging; Male; Neural Pathways; Occipital Lobe; Prefrontal Cortex; Valproic Acid | 2019 |
Regulation of Glycogen Content in Astrocytes via Cav-1/PTEN/AKT/GSK-3β Pathway by Three Anti-bipolar Drugs.
Topics: Animals; Animals, Newborn; Antimanic Agents; Astrocytes; Bipolar Disorder; Carbamazepine; Caveolin 1; Cells, Cultured; Dose-Response Relationship, Drug; Glycogen; Glycogen Synthase Kinase 3 beta; Lithium; Mice; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Signal Transduction; Valproic Acid | 2018 |
Diacylglycerol kinase (DGKA) regulates the effect of the epilepsy and bipolar disorder treatment valproic acid in
Topics: Amino Acid Sequence; Anticonvulsants; Bipolar Disorder; Diacylglycerol Kinase; Dictyostelium; Diglycerides; Epilepsy; Green Fluorescent Proteins; Lithium; Models, Biological; Mutation; Valproic Acid | 2018 |
Nociceptin/orphanin FQ receptor agonists increase aggressiveness in the mouse resident-intruder test.
Topics: Aggression; Agonistic Behavior; Animals; Anxiety; Bipolar Disorder; Carbamazepine; Cycloheptanes; Depression; Depressive Disorder; Disease Models, Animal; Fenclonine; Lithium; Male; Mice; Mice, Knockout; Nociceptin; Nociceptin Receptor; Opioid Peptides; Piperidines; Receptors, Opioid; Valproic Acid | 2019 |
Cortical thickness and subcortical volumes alterations in euthymic bipolar I patients treated with different mood stabilizers.
Topics: Adult; Antimanic Agents; Bipolar Disorder; Cerebral Cortex; Female; Humans; Image Processing, Computer-Assisted; Lithium; Magnetic Resonance Imaging; Male; Prefrontal Cortex; Valproic Acid | 2019 |
Effect of Lithium and Valproate on Proliferation and Migration of Limbal Epithelial Stem/Progenitor Cells.
Topics: Cell Movement; Cell Proliferation; Cell Survival; Cells, Cultured; Enzyme Inhibitors; Flow Cytometry; Humans; Immunohistochemistry; Limbus Corneae; Lithium; Mesenchymal Stem Cells; Signal Transduction; Valproic Acid | 2019 |
Blood Lithium Monitoring Practices in a Population-Based Sample of Older Adults.
Topics: Aged; Biomarkers; Bipolar Disorder; Calcium; Case-Control Studies; Cohort Studies; Creatinine; Drug Monitoring; Female; Humans; Lithium; Male; Ontario; Thyrotropin; Valproic Acid | 2018 |
Gene expression effects of lithium and valproic acid in a serotonergic cell line.
Topics: Animals; Bipolar Disorder; Cell Adhesion; Cell Line; Chemotaxis; Extracellular Matrix; Gene Ontology; Lithium; Rats; Real-Time Polymerase Chain Reaction; RNA-Seq; Serotonergic Neurons; Transcriptional Activation; Transcriptome; Valproic Acid | 2019 |
Timing of onset of lithium relapse prevention - how early, how late?
Topics: Antipsychotic Agents; Bipolar Disorder; Humans; Lithium; Secondary Prevention; Valproic Acid | 2019 |
A comparative study of detection of myocarditis induced by clozapine: With and without cardiac monitoring.
Topics: Adult; Antipsychotic Agents; Clozapine; Drug Therapy, Combination; Female; Humans; Incidence; Inpatients; Lithium; Male; Middle Aged; Monitoring, Physiologic; Myocarditis; Psychotic Disorders; Risk Factors; Valproic Acid; Young Adult | 2019 |
Indoleamine-2,3-dioxygenase-1 is a molecular target for the protective activity of mood stabilizers against mania-like behavior induced by d-amphetamine.
Topics: Animals; Antimanic Agents; Bipolar Disorder; Calcium; Dextroamphetamine; Glutathione Peroxidase; Indoleamine-Pyrrole 2,3,-Dioxygenase; Lithium; Locomotion; Male; Membrane Potential, Mitochondrial; Mice, Inbred C57BL; Mice, Knockout; Mitochondria; Prefrontal Cortex; Superoxide Dismutase; Valproic Acid | 2020 |
Sex difference in the progression of manic symptoms during acute hospitalization: A prospective pilot study.
Topics: Adult; Aggression; Antimanic Agents; Bipolar Disorder; Disease Progression; Female; Follow-Up Studies; Hospitalization; Humans; Lithium; Longitudinal Studies; Male; Pilot Projects; Prospective Studies; Psychiatric Status Rating Scales; Sex Factors; Turkey; Valproic Acid | 2020 |
Immunopharmacological management of COVID-19: Potential therapeutic role of valproic acid.
Topics: Antimanic Agents; Betacoronavirus; Coronavirus; Coronavirus Infections; COVID-19; Humans; Lithium; Pandemics; Pneumonia, Viral; SARS-CoV-2; Valproic Acid | 2020 |
Association of Lithium Use and a Higher Serum Concentration of Lithium With the Risk of Declining Renal Function in Older Adults: A Population-Based Cohort Study.
Topics: Aged; Antimanic Agents; Humans; Kidney; Lithium; Longitudinal Studies; Male; Propensity Score; Renal Insufficiency; Risk Factors; Valproic Acid | 2020 |
Bipolar Disorder and Outcomes of Monotherapy with Lithium, Valproate, Quetiapine, Olanzapine, Venlafaxine, and Citalopram.
Topics: Antipsychotic Agents; Bipolar Disorder; Citalopram; Humans; Lithium; Olanzapine; Quetiapine Fumarate; Retrospective Studies; Valproic Acid; Venlafaxine Hydrochloride | 2021 |
Transcriptional analysis of sodium valproate in a serotonergic cell line reveals gene regulation through both HDAC inhibition-dependent and independent mechanisms.
Topics: Animals; Antimanic Agents; Cell Line; Computational Biology; Gene Expression Regulation; Histone Deacetylase Inhibitors; Histone Deacetylases; Lithium; Rats; RNA-Seq; Serotonin; Transcription, Genetic; Transcriptional Activation; Valproic Acid | 2021 |
Lithium increases mitochondrial respiration in iPSC-derived neural precursor cells from lithium responders.
Topics: Antimanic Agents; Humans; Induced Pluripotent Stem Cells; Lithium; Neural Stem Cells; Respiration; Valproic Acid | 2021 |
Antidepressant effect of repetitive transcranial magnetic stimulation is not impaired by intake of lithium or antiepileptic drugs.
Topics: Anticonvulsants; Antidepressive Agents; Antipsychotic Agents; Depression; Humans; Lamotrigine; Lithium; Transcranial Magnetic Stimulation; Treatment Outcome; Valproic Acid | 2021 |
Lithium use in a patient on haemodialysis with bipolar affective disorder and lithium-induced nephropathy.
Topics: Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Humans; Kidney Diseases; Lithium; Male; Mood Disorders; Neoplasm Recurrence, Local; Renal Dialysis; Valproic Acid | 2021 |
Plasma circulating cell-free mitochondrial DNA in depressive disorders.
Topics: Biomarkers; Cell-Free Nucleic Acids; DNA, Mitochondrial; Humans; Lamotrigine; Lithium; Mental Disorders; Valproic Acid | 2021 |
Long-term use of valproic acid reduced mortality in bipolar disorder patients in a Taiwanese population: An association analysis using the national health insurance research database (NHIRD).
Topics: Bipolar Disorder; Epilepsy; Humans; Lithium; Male; National Health Programs; Valproic Acid | 2022 |
Gender and Body Mass Index-Related Serum Level of Adipokines and Metabolic Syndrome Components in Bipolar Patients Who Received Lithium and Valproic Acid.
Topics: Adipokines; Adiponectin; Bipolar Disorder; Body Mass Index; Cholesterol, HDL; Female; Humans; Leptin; Lithium; Male; Metabolic Syndrome; Obesity; Valproic Acid | 2022 |
GLP-1 agonist liraglutide improves ouabain-induced mania and depressive state
Topics: Animals; Antioxidants; Glucagon-Like Peptide 1; Glutathione; Glycogen Synthase Kinase 3 beta; Liraglutide; Lithium; Mania; Ouabain; Oxidants; Rats; Sucrose; Valproic Acid | 2022 |
Suicide death over the first year of lithium versus valproate treatment in cohorts with and without bipolar disorder.
Topics: Antimanic Agents; Bipolar Disorder; Humans; Lithium; Suicide; Valproic Acid | 2022 |
Bipolar disorder, mood stabilizers and cognitive flexibility: Translationally dissecting illness from drug effects.
Topics: Animals; Anticonvulsants; Antimanic Agents; Bipolar Disorder; Cognition; Humans; Lithium; Rats; Valproic Acid | 2022 |
Association between serum lithium level and incidence of COVID-19 infection.
Topics: Antimanic Agents; Bipolar Disorder; COVID-19; Humans; Incidence; Lithium; Lithium Compounds; Valproic Acid | 2022 |
Association of Lithium Treatment With the Risk of Osteoporosis in Patients With Bipolar Disorder.
Topics: Adult; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Female; Humans; Lamotrigine; Lithium; Lithium Compounds; Male; Middle Aged; Osteoporosis; Retrospective Studies; Valproic Acid | 2022 |
Response to lithium and anticonvulsants among patients with bipolar disorder with and without comorbid epilepsy - A nation-wide population-based longitudinal study.
Topics: Anticonvulsants; Antipsychotic Agents; Bipolar Disorder; Comorbidity; Epilepsy; Humans; Lamotrigine; Lithium; Longitudinal Studies; Valproic Acid | 2022 |
Relationship between lithium carbonate and the risk of Parkinson-like events in patients with bipolar disorders: A multivariate analysis using the Japanese adverse drug event report database.
Topics: Antimanic Agents; Bipolar Disorder; Drug-Related Side Effects and Adverse Reactions; Humans; Japan; Lithium; Lithium Carbonate; Middle Aged; Multivariate Analysis; Parkinson Disease; Valproic Acid | 2022 |
Comparative effectiveness of mood stabilizers and antipsychotics in the prevention of hospitalization after lithium discontinuation in bipolar disorder.
Topics: Anticonvulsants; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Hospitalization; Humans; Lithium; Valproic Acid | 2022 |
Phosphatidic acid inhibits inositol synthesis by inducing nuclear translocation of kinase IP6K1 and repression of myo-inositol-3-P synthase.
Topics: AMP-Activated Protein Kinases; Animals; Fibroblasts; Glucose; Humans; Inositol; Lithium; Mammals; Mice; Phosphatidic Acids; Phospholipase D; Phosphotransferases (Phosphate Group Acceptor); Valproic Acid | 2022 |
Effect of valproate and lithium on dementia onset risk in bipolar disorder patients.
Topics: Aged; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Dementia; Humans; Lithium; Valproic Acid | 2022 |
Lithium produces bi-directionally regulation of mood disturbance, acts synergistically with anti-depressive/-manic agents, and did not deteriorate the cognitive impairment in murine model of bipolar disorder.
Topics: Animals; Anticonvulsants; Antidepressive Agents; Antimanic Agents; Bipolar Disorder; Cognitive Dysfunction; Disease Models, Animal; Lamotrigine; Lithium; Mice; Valproic Acid | 2022 |
Real-world effectiveness of mood stabilizer use in schizophrenia.
Topics: Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Carbamazepine; Female; Humans; Lamotrigine; Lithium; Male; Schizophrenia; Valproic Acid | 2023 |
Prescribing changes for bipolar patients discharged from two public psychiatric hospitals in Taiwan, 2006-2019.
Topics: Anticonvulsants; Antidepressive Agents; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Carbamazepine; Hospitals, Psychiatric; Humans; Lamotrigine; Lithium; Patient Discharge; Retrospective Studies; Taiwan; Valproic Acid | 2022 |
Safety of inositol supplementation in patients taking lithium or valproic acid: a pilot clinical study.
Topics: Adolescent; Adult; Dietary Supplements; Glucose; Humans; Inositol; Insulin; Lactalbumin; Lithium; Pilot Projects; Quality of Life; Thyrotropin; Triglycerides; Valproic Acid | 2022 |
Effects of different doses of lithium on the central nervous system in the rat valproic acid model of autism.
Topics: Animals; Autism Spectrum Disorder; Autistic Disorder; Hippocampus; Lithium; Lithium Compounds; Rats; Valproic Acid | 2023 |
Lumateperone Normalizes Pathological Levels of Acute Inflammation through Important Pathways Known to Be Involved in Mood Regulation.
Topics: Animals; Cytokines; Depressive Disorder, Major; Female; Inflammation; Lithium; Male; Mammals; Mice; Mice, Inbred C57BL; Rats; Rats, Sprague-Dawley; TOR Serine-Threonine Kinases; Valproic Acid | 2023 |
Fourteen-year trends in the prescribing patterns of pediatric bipolar patients discharged from two public mental hospitals in Taiwan.
Topics: Antidepressive Agents; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Child; Hospitals, Psychiatric; Humans; Lithium; Patient Discharge; Psychotropic Drugs; Taiwan; Valproic Acid | 2023 |
Pharmacological treatment of bipolar disorder and risk of diabetes mellitus: A nationwide study of 30,451 patients.
Topics: Anticonvulsants; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Diabetes Mellitus; Humans; Lamotrigine; Lithium; Valproic Acid | 2023 |
Pharmacological Strategies for Bipolar Disorders in Acute Phases and Chronic Management with a Special Focus on Lithium, Valproic Acid, and Atypical Antipsychotics.
Topics: Anticonvulsants; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Cyclothymic Disorder; Humans; Lithium; Valproic Acid | 2023 |
The paradox of vanishing lithium.
Topics: Antimanic Agents; Bipolar Disorder; Humans; Lithium; Lithium Compounds; Valproic Acid | 2023 |
Valproate-related neutropenia and lithium-related leukocytosis in patients treated with clozapine: a retrospective cohort study.
Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Humans; Leukocytosis; Lithium; Male; Neutropenia; Retrospective Studies; Valproic Acid | 2023 |
Increased levels of lipid and protein oxidation in rat prefrontal cortex after treatment by lithium, valproic acid, and olanzapine.
Topics: Advanced Oxidation Protein Products; Animals; Antipsychotic Agents; Benzodiazepines; Lithium; Male; Olanzapine; Prefrontal Cortex; Rats; Rats, Wistar; Valproic Acid | 2023 |
Lithium and Valproic Acid in Bipolar Disorders and Beyond.
Topics: Antimanic Agents; Bipolar Disorder; Humans; Lithium; Lithium Compounds; Valproic Acid | 2023 |
Absolute and Relative Risks of Kidney Outcomes Associated With Lithium vs Valproate Use in Sweden.
Topics: Acute Kidney Injury; Adult; Albuminuria; Cohort Studies; Creatinine; Female; Humans; Kidney; Lithium; Lithium Compounds; Middle Aged; Renal Insufficiency, Chronic; Risk; Sweden; Valproic Acid | 2023 |