valproic acid and levodopa

valproic acid has been researched along with levodopa in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-199010 (37.04)18.7374
1990's4 (14.81)18.2507
2000's6 (22.22)29.6817
2010's7 (25.93)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jolivette, LJ; Ward, KW1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Leijnse-Ybema, HJ; Tan, BK; Zee, MF1
Marsden, CD; Parkes, JD; Price, PA1
Godwin-Austen, RB1
Anavekar, SN; Davis, HT; Tsianco, MC; Wardell, WM1
Calne, DB; Eng, N; Nutt, J; Plotkin, C; Williams, A; Ziegler, M1
MacMillan, V1
Cavagnini, F; Danesi, L; Dubini, A; Invitti, C1
Calderazzo, L; Cepeda, C; Naquet, R; Stutzmann, JM; Valin, A1
Dahlström, S; Koulu, M; Lammintausta, R1
Georgiev, V; Markovska, V1
Hamada, T; Matsuura, T; Moriwaka, F; Tashiro, K; Yoshida, K1
Kagaya, A; Motohashi, N; Saito, H; Takebayashi, M; Yamawaki, S1
Caffarri, G; Capretti, L; Chiodera, P; Cigarini, C; Coiro, V; Gramellini, D; Necchi Ghiri, S; Volpi, R1
Onofrj, M; Paci, C; Thomas, A1
Ehrenberg, BL; Eisensehr, I; Noachtar, S; Rogge Solti, S1
Fernandez, HH; Hicks, CW; Itin, I; Pandya, MM1
Foote, KD; Hassan, A; Iyer, S; McFarland, NR; Okun, MS; Rodriguez, RL; Sriram, A; Ward, HE1
Factor, SA; Silver, M1
Epstein, J; Hayes, MT; Lai, L; Madiedo, CJ1

Reviews

1 review(s) available for valproic acid and levodopa

ArticleYear
[Myoclonus induced by some benzodiazepines in the Papio papio. Comparison with myoclonus induced by intermittent light stimulation (author's transl)].
    Revue d'electroencephalographie et de neurophysiologie clinique, 1982, Volume: 12, Issue:1

    Topics: Allylglycine; Animals; Anti-Anxiety Agents; Apomorphine; Diazepam; Levodopa; Lorazepam; Myoclonus; Papio; Photic Stimulation; Serotonin; Valproic Acid

1982

Trials

5 trial(s) available for valproic acid and levodopa

ArticleYear
Sodium valproate in Huntington's chorea.
    Clinical neurology and neurosurgery, 1976, Volume: 79, Issue:1

    Topics: Clinical Trials as Topic; Drug Evaluation; Drug Tolerance; Female; Humans; Huntington Disease; Levodopa; Middle Aged; Valerates; Valproic Acid

1976
Sodium valproate in the treatment of levodopa-induced dyskinesia.
    Journal of neurology, neurosurgery, and psychiatry, 1978, Volume: 41, Issue:8

    Topics: Clinical Trials as Topic; Double-Blind Method; Dyskinesia, Drug-Induced; Female; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Valerates; Valproic Acid

1978
Treatment of Parkinson's disease with sodium valproate: clinical, pharmacological, and biochemical observations.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 1979, Volume: 6, Issue:3

    Topics: Aged; Carbidopa; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; gamma-Aminobutyric Acid; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Valproic Acid

1979
Altered neuroendocrine control of GH secretion in normal women of advanced reproductive age.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 1997, Volume: 52, Issue:4

    Topics: Adult; Aging; Dopamine Agonists; Female; GABA Agonists; Growth Hormone-Releasing Hormone; Human Growth Hormone; Humans; Insulin-Like Growth Factor I; Levodopa; Middle Aged; Neurosecretory Systems; Reference Values; Reproduction; Serotonin Receptor Agonists; Sumatriptan; Valproic Acid

1997
Treatment of idiopathic restless legs syndrome (RLS) with slow-release valproic acid compared with slow-release levodopa/benserazid.
    Journal of neurology, 2004, Volume: 251, Issue:5

    Topics: Adult; Aged; Anticonvulsants; Antiparkinson Agents; Benserazide; Cross-Over Studies; Double-Blind Method; Female; Follow-Up Studies; Humans; Levodopa; Male; Middle Aged; Polysomnography; Restless Legs Syndrome; Surveys and Questionnaires; Time Factors; Treatment Outcome; Valproic Acid

2004

Other Studies

21 other study(ies) available for valproic acid and levodopa

ArticleYear
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.
    Journal of pharmaceutical sciences, 2005, Volume: 94, Issue:7

    Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution

2005
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
The treatment of the choreas and athetotic dystonias.
    Journal of the Royal College of Physicians of London, 1979, Volume: 13, Issue:1

    Topics: Adult; Athetosis; Benzodiazepines; Child; Chorea; Dystonia; Haloperidol; Humans; Levodopa; Movement Disorders; Phenelzine; Phenothiazines; Pimozide; Tetrabenazine; Valproic Acid

1979
Postmarketing surveillance of new drugs: II. Case studies.
    Journal of clinical pharmacology, 1979, Volume: 19, Issue:4

    Topics: Azauridine; Bacteriuria; Contraceptives, Oral; Costs and Cost Analysis; Double-Blind Method; Drug-Related Side Effects and Adverse Reactions; Humans; Ketamine; Levodopa; Research Design; United States; United States Food and Drug Administration; Valproic Acid

1979
The effects of the anticonvulsant valproic acid on cerebral indole amine metabolism.
    Canadian journal of physiology and pharmacology, 1979, Volume: 57, Issue:8

    Topics: 5-Hydroxytryptophan; Animals; Biogenic Amines; Brain; Dopamine; Female; Hydroxyindoleacetic Acid; Indoles; Levodopa; Rats; Serotonin; Tryptophan; Valproic Acid

1979
Neuroendocrine effects of chronic administration of sodium valproate in epileptic patients.
    Acta endocrinologica, 1988, Volume: 118, Issue:3

    Topics: Adolescent; Adrenocorticotropic Hormone; Child; Epilepsy; Female; Growth Hormone; Growth Hormone-Releasing Hormone; Humans; Hypothalamo-Hypophyseal System; Levodopa; Male; Prolactin; Thyrotropin; Valproic Acid

1988
Effects of some gamma-aminobutyric acid (GABA)-ergic drugs on the dopaminergic control of human growth hormone secretion.
    The Journal of clinical endocrinology and metabolism, 1980, Volume: 51, Issue:1

    Topics: Adult; Apomorphine; Baclofen; Diazepam; Dopamine; gamma-Aminobutyric Acid; Growth Hormone; Humans; Levodopa; Male; Valproic Acid

1980
Interrelations between dopaminergic and GABA-ergic transmitter mechanisms in apomorphine stereotypy.
    Acta physiologica et pharmacologica Bulgarica, 1982, Volume: 8, Issue:3

    Topics: Aminooxyacetic Acid; Animals; Apomorphine; Dopamine; gamma-Aminobutyric Acid; Haloperidol; Humans; Levodopa; Male; Picrotoxin; Rats; Stereotyped Behavior; Valproic Acid

1982
Myoclonus and seizures in a patient with parkinsonism: induction by levodopa and its confirmation on SEPs.
    The Japanese journal of psychiatry and neurology, 1993, Volume: 47, Issue:3

    Topics: Aged; Electroencephalography; Electromyography; Epilepsies, Myoclonic; Epilepsy, Generalized; Evoked Potentials, Somatosensory; Female; Humans; Levodopa; Neurologic Examination; Parkinson Disease; Seizures; Valproic Acid

1993
Effect of acute treatment with sodium valproate on catecholamine and serotonin synthesis in mouse cerebral cortex.
    Neuropsychobiology, 1995, Volume: 32, Issue:3

    Topics: Animals; Catecholamines; Cerebral Cortex; Levodopa; Male; Mice; Mice, Inbred ICR; Muscimol; Picrotoxin; Serotonin; Time Factors; Valproic Acid

1995
Reversible parkinsonism induced by prolonged treatment with valproate.
    Journal of neurology, 1998, Volume: 245, Issue:12

    Topics: Aged; Anticonvulsants; Antiparkinson Agents; Carbidopa; Female; Humans; Levodopa; Male; Middle Aged; Parkinson Disease, Secondary; Remission Induction; Seizures; Valproic Acid

1998
Valproate for the treatment of medication-induced impulse-control disorders in three patients with Parkinson's disease.
    Parkinsonism & related disorders, 2011, Volume: 17, Issue:5

    Topics: Adult; Anticonvulsants; Antiparkinson Agents; Disruptive, Impulse Control, and Conduct Disorders; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Valproic Acid

2011
Valproate as a treatment for dopamine dysregulation syndrome (DDS) in Parkinson's disease.
    Journal of neurology, 2013, Volume: 260, Issue:2

    Topics: Aged; Aged, 80 and over; Akathisia, Drug-Induced; Anticonvulsants; Carbidopa; Disruptive, Impulse Control, and Conduct Disorders; Dopamine Agents; Drug Combinations; Female; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Valproic Acid

2013
Valproic acid-induced parkinsonism: levodopa responsiveness with dyskinesia.
    Parkinsonism & related disorders, 2013, Volume: 19, Issue:8

    Topics: Adult; Aged; Dyskinesia, Drug-Induced; Female; Humans; Levodopa; Male; Middle Aged; Parkinson Disease, Secondary; Valproic Acid

2013
Successful treatment of dopamine dysregulation syndrome with valproic acid.
    The Journal of neuropsychiatry and clinical neurosciences, 2014,Summer, Volume: 26, Issue:3

    Topics: Antimanic Agents; Carbidopa; Compulsive Behavior; Dopamine Agonists; Drug Combinations; Female; Humans; Levodopa; Middle Aged; Parkinson Disease; Valproic Acid

2014