valproic acid and leptin

valproic acid has been researched along with leptin in 37 studies

Research

Studies (37)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (2.70)	18.2507
2000's	18 (48.65)	29.6817
2010's	14 (37.84)	24.3611
2020's	4 (10.81)	2.80

Authors

Authors	Studies
Basciani, F; Chiarelli, F; de Martino, M; Morgese, G; Morresi, S; Verrotti, A	1
Isojärvi, JI; Knip, M; Kotila, M; Pakarinen, A; Pylvänen, V; Turkka, J	1
Berberoğlu, M; Caksen, H; Deda, G	1
Basile, VS; Kennedy, SH; Mancini, DA; McIntyre, RS; Srinivasan, J	1
Chiarelli, F; di Corcia, G; Morgese, G; Salladini, C; Trotta, D; Verrotti, A	1
Lagace, DC; McLeod, RS; Nachtigal, MW	1
Chiarelli, F; Greco, R; Iannetti, P; Latini, G; Verrotti, A	1
Aydin, K; Bideci, A; Gucuyener, K; Okuyaz, C; Serdaroglu, A	1
Bauer, G; El-Khatib, F; Hoppichler, F; Lechleitner, M; Luef, GJ; Naser, A; Rauchenzauner, M; Trinka, E; Unterberger, I; Waldmann, M	1
Hamed, SA	1
Kim, JY; Lee, HW	1
Huang, SP; Li, D; Li, J	2
Penning, C; van der Wouden, JC	1
Ebenbichler, CF; Ernst, B; Haberlandt, E; Hoppichler, F; Karall, D; Luef, G; Rauchenzauner, M; Rostasy, K; Scholl-Bürgi, S	1
Akinci, A; Gungor, S; Ozerol, IH; Tabel, Y; Yologlu, S; Yücel, G	1
Ebenbichler, CF; Engl, J; Haberlandt, E; Karall, D; Laimer, M; Luef, G; Rauchenzauner, M; Schoenherr, E; Scholl-Bürgi, S; Tatarczyk, T	1
Anton, SD; Greenway, FL; Han, H; Martin, CK; Smith, SR	1
Fida, NM; Hamed, EA; Hamed, SA	1
Jiang, B; Kenna, HA; Rasgon, NL	1
Chang, HH; Chen, PS; Chou, CH; Gean, PW; Lu, RB; Tsai, HC; Yang, YK	1
Balestri, P; Barlocco, EG; Casarosa, E; Grosso, S; Luisi, S; Matera, M; Mostardini, R; Petraglia, F	1
Camurdan, O; Cansu, A; Cinaz, P; Hırfanoğlu, T; Serdaroglu, A	1
Aksoy, A; Deger, O; Hosver, I; Karagüzel, G; Sönmez, FM	1
Aydin, K; Kiyici, A; Oran, B; Tokgoz, H	1
Demir, CF; Inci, MF; Ozkan, F	1
Aydin, K; Oran, B; Tokgoz, H	1
Aksoy, A; Aliyazicioglu, R; Deger, O; Fazlioglu, K; Karaguzel, G; Sonmez, FM; Zaman, D	1
Belcastro, V; D'Egidio, C; Striano, P; Verrotti, A	1
Berkovic, SF; Collins, M; Hill, KD; Kantor, S; Lawrence, KM; Makovey, J; O'Brien, TJ; Petty, SJ; Sambrook, PN; Wark, JD	1
Chang, HH; Chen, PS; Chen, SL; Huang, CC; Huang, SY; Lee, CC; Lee, SY; Lu, RB; Yang, YK	1
Akgün, S; Kahraman, A; Köken, T	1
Alver, A; Cansu, A; Çiçek, NP; Kamaşak, T; Okten, A; Serin, M	1
Bengesser, SA; Birner, A; Dalkner, N; Fellendorf, FT; Hamm, C; Kapfhammer, HP; Lenger, M; Maget, A; Mangge, H; Pilz, R; Platzer, M; Queissner, R; Reininghaus, B; Reininghaus, EZ; Reiter, A; Zelzer, S	1
Demirel, A; Kilic, H; Uysal, S	1
Amiriani, T; Dolab, N; Kamkar, MZ; Marjani, A; Marjani, M; Yuzugulen, J	1
Altunkaynak, Z; Bilgici, B; Gümrükçüoğlu, Tİ; Karaustaoğlu, A; Tunçel, ÖK	1

Reviews

3 review(s) available for valproic acid and leptin

Article	Year
Leptin and insulin homeostasis in epilepsy: relation to weight adverse conditions. Epilepsy research, 2007, Volume: 75, Issue:1 Topics: Animals; Anticonvulsants; Body Weight; Epilepsy; Homeostasis; Humans; Insulin; Leptin; Valproic Acid	2007
Reproductive and metabolic abnormalities associated with bipolar disorder and its treatment. Harvard review of psychiatry, 2009, Volume: 17, Issue:2 Topics: Bipolar Disorder; Dyslipidemias; Endocrine System Diseases; Female; Humans; Hypogonadism; Hypothalamo-Hypophyseal System; Leptin; Lithium Carbonate; Menstruation; Obesity; Pituitary-Adrenal System; Polycystic Ovary Syndrome; Psychotropic Drugs; Valproic Acid	2009
Metabolic and endocrine effects of valproic acid chronic treatment. Epilepsy research, 2013, Volume: 107, Issue:1-2 Topics: Anticonvulsants; Epilepsy; Humans; Hyperinsulinism; Insulin Resistance; Leptin; Metabolic Syndrome; Valproic Acid; Weight Gain	2013

Trials

5 trial(s) available for valproic acid and leptin

Article	Year
Antipsychotic-induced weight gain: bipolar disorder and leptin. Journal of clinical psychopharmacology, 2003, Volume: 23, Issue:4 Topics: Adolescent; Adult; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Body Mass Index; Female; Humans; Leptin; Lithium; Male; Middle Aged; Olanzapine; Pirenzepine; Risperidone; Valproic Acid; Weight Gain	2003
Serum insulin, leptin, and neuropeptide y levels in epileptic children treated with valproate. Journal of child neurology, 2005, Volume: 20, Issue:10 Topics: Anticonvulsants; Blood Glucose; Body Mass Index; Child; Child, Preschool; Epilepsy; Female; Humans; Hydrocortisone; Hypoglycemic Agents; Insulin; Leptin; Male; Neuropeptide Y; Valproic Acid; Weight Gain	2005
The role of ghrelin in weight gain and growth in epileptic children using valproate. Journal of child neurology, 2007, Volume: 22, Issue:12 Topics: Adolescent; Anticonvulsants; Blood Glucose; Body Height; Body Mass Index; Body Weight; C-Peptide; Child; Child, Preschool; Epilepsy; Female; Ghrelin; Humans; Insulin; Insulin Resistance; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor I; Leptin; Male; Puberty; Valproic Acid; Weight Gain	2007
Effect of valproic acid treatment on body composition, leptin and the soluble leptin receptor in epileptic children. Epilepsy research, 2008, Volume: 80, Issue:2-3 Topics: Adolescent; Anthropology, Physical; Anticonvulsants; Body Composition; Body Mass Index; Child; Cross-Sectional Studies; Dose-Response Relationship, Drug; Epilepsy; Female; Humans; Leptin; Male; Receptors, Leptin; Sex Factors; Valproic Acid	2008
Effect of valproic acid on body weight, food intake, physical activity and hormones: results of a randomized controlled trial. Journal of psychopharmacology (Oxford, England), 2009, Volume: 23, Issue:7 Topics: Adolescent; Adult; Anticonvulsants; Attitude; Blood Glucose; Body Weight; Creatinine; Delayed-Action Preparations; Eating; Feeding Behavior; Female; Ghrelin; Glucagon-Like Peptide 1; Humans; Insulin; Leptin; Lipids; Male; Middle Aged; Motor Activity; Patient Compliance; Peptide Fragments; Peptide YY; Serum Albumin; Valproic Acid	2009

Other Studies

29 other study(ies) available for valproic acid and leptin

Article	Year
Serum leptin changes in epileptic patients who gain weight after therapy with valproic acid. Neurology, 1999, Jul-13, Volume: 53, Issue:1 Topics: Adolescent; Androgens; Anticonvulsants; Blood Glucose; Body Mass Index; Epilepsy; Female; Follicle Stimulating Hormone; Follow-Up Studies; Humans; Insulin; Leptin; Luteinizing Hormone; Proteins; Reference Values; Sex Hormone-Binding Globulin; Time Factors; Valproic Acid; Weight Gain	1999
Serum insulin and leptin levels in valproate-associated obesity. Epilepsia, 2002, Volume: 43, Issue:5 Topics: Adult; Body Mass Index; Body Weight; Epilepsy; Female; Humans; Insulin; Insulin Resistance; Leptin; Male; Obesity; Sex Factors; Valproic Acid	2002
Does long-term use of valproate cause weight gain in prepubertal epileptic children? The International journal of neuroscience, 2002, Volume: 112, Issue:10 Topics: Anticonvulsants; Body Mass Index; Child; Epilepsy; Female; Humans; Leptin; Male; Time; Valproic Acid; Weight Gain	2002
Serum insulin and leptin levels and valproate-associated obesity. Epilepsia, 2003, Volume: 44, Issue:12 Topics: Adult; Anticonvulsants; Body Composition; Body Mass Index; Child; Epilepsy; Feedback; Female; Humans; Insulin; Leptin; Male; Obesity; Risk Factors; Valproic Acid	2003
Valproic acid inhibits leptin secretion and reduces leptin messenger ribonucleic acid levels in adipocytes. Endocrinology, 2004, Volume: 145, Issue:12 Topics: 3T3-L1 Cells; Adipocytes; Animals; Anticonvulsants; Carbon Radioisotopes; CCAAT-Enhancer-Binding Protein-alpha; CCAAT-Enhancer-Binding Proteins; Cycloheximide; DNA-Binding Proteins; Energy Metabolism; Gene Expression; Glucose; Leptin; Lipid Metabolism; Mice; PPAR gamma; Protein Synthesis Inhibitors; RNA, Messenger; Sterol Regulatory Element Binding Protein 1; Transcription Factors; Valproic Acid	2004
Leptin, ghrelin, and adiponectin in epileptic patients treated with valproic acid. Neurology, 2005, Dec-13, Volume: 65, Issue:11 Topics: Adiponectin; Adipose Tissue; Adolescent; Adult; Anticonvulsants; Appetite Regulation; Body Weight; Brain; Epilepsy; Female; Ghrelin; Humans; Insulin; Leptin; Obesity; Peptide Hormones; Up-Regulation; Valproic Acid	2005
Valproate, weight gain and carbohydrate craving: a gender study. Seizure, 2007, Volume: 16, Issue:3 Topics: Adult; Anticonvulsants; Appetite; Body Mass Index; Dietary Carbohydrates; Epilepsy; Female; Glucose; Homeostasis; Humans; Leptin; Male; Sex Factors; Valproic Acid; Weight Gain	2007
Metabolic and hormonal disturbances in women with epilepsy on antiepileptic drug monotherapy. Epilepsia, 2007, Volume: 48, Issue:7 Topics: Adolescent; Adult; Anticonvulsants; Blood Glucose; Body Mass Index; Carbamazepine; Comorbidity; Epilepsy; Female; Humans; Insulin; Insulin Resistance; Lamotrigine; Leptin; Lipids; Metabolic Syndrome; Obesity; Risk Factors; Sex Factors; Triazines; Valproic Acid	2007
[Effects of topiramate and valproate acid on serum insulin and leptin levels in young and adult rats]. Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2007, Volume: 9, Issue:3 Topics: Age Factors; Animals; Anticonvulsants; Body Weight; Female; Fructose; Insulin; Leptin; Rats; Rats, Sprague-Dawley; Topiramate; Valproic Acid	2007
Increased plasma leptin levels and valproate use in patients with Rett syndrome. The Journal of pediatrics, 2007, Volume: 151, Issue:4 Topics: Anticonvulsants; Biomarkers; Growth Disorders; Humans; Leptin; Rett Syndrome; Valproic Acid	2007
Adiponectin and visfatin concentrations in children treated with valproic acid. Epilepsia, 2008, Volume: 49, Issue:2 Topics: Adiponectin; Adipose Tissue; Age Factors; Anticonvulsants; Blood Glucose; Child; Epilepsy; Female; Humans; Insulin Resistance; Leptin; Male; Nicotinamide Phosphoribosyltransferase; Valproic Acid; Weight Gain	2008
States of serum leptin and insulin in children with epilepsy: risk predictors of weight gain. European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 2009, Volume: 13, Issue:3 Topics: Adolescent; Age Factors; Anticonvulsants; Body Mass Index; Carbamazepine; Case-Control Studies; Child; Epilepsy; Female; Humans; Hyperinsulinism; Insulin; Lamotrigine; Leptin; Lipids; Male; Predictive Value of Tests; Risk Assessment; Sex Factors; Triazines; Valproic Acid; Weight Gain	2009
[Effects of valproate acid on blood lipid, serum leptin and cerebral cortex in juvenile and adult rats]. Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2010, Volume: 12, Issue:6 Topics: Animals; Anticonvulsants; Body Weight; Cerebral Cortex; Female; Leptin; Lipids; Myelin Sheath; Rats; Rats, Sprague-Dawley; Valproic Acid	2010
C825T polymorphism of the GNB3 gene on valproate-related metabolic abnormalities in bipolar disorder patients. Journal of clinical psychopharmacology, 2010, Volume: 30, Issue:5 Topics: Adult; Alleles; Bipolar Disorder; Body Mass Index; Female; Genetic Carrier Screening; Heterotrimeric GTP-Binding Proteins; Humans; Leptin; Male; Middle Aged; Polymorphism, Single Nucleotide; Protein Subunits; Valproic Acid; Young Adult	2010
Circulating levels of allopregnanolone, a neuroactive steroid, and leptin during treatment with valproic acid in children with epilepsy. Neuroendocrinology, 2011, Volume: 93, Issue:3 Topics: Anticonvulsants; Child; Epilepsy; Female; Humans; Immunoassay; Leptin; Male; Obesity; Pregnanolone; Valproic Acid; Weight Gain	2011
Serum insulin, cortisol, leptin, neuropeptide Y, galanin and ghrelin levels in epileptic children receiving valproate. Hormone research in paediatrics, 2011, Volume: 76, Issue:1 Topics: Adolescent; Child; Child, Preschool; Epilepsy; Galanin; Ghrelin; Humans; Hydrocortisone; Insulin; Leptin; Neuropeptide Y; Valproic Acid; Weight Gain	2011
The effects of antiepileptic drugs on the relationships between leptin levels and bone turnover in prepubertal children with epilepsy. Journal of pediatric endocrinology & metabolism : JPEM, 2011, Volume: 24, Issue:9-10 Topics: Anticonvulsants; Biomarkers; Bone Density; Bone Remodeling; Carbamazepine; Child; Child, Preschool; Cross-Sectional Studies; Epilepsy; Female; Humans; Leptin; Male; Valproic Acid	2011
Plasma leptin, neuropeptide Y, ghrelin, and adiponectin levels and carotid artery intima media thickness in epileptic children treated with valproate. Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2012, Volume: 28, Issue:7 Topics: Adiponectin; Age Factors; Anticonvulsants; Blood Glucose; Body Mass Index; Carotid Intima-Media Thickness; Child; Epilepsy; Female; Follow-Up Studies; Ghrelin; Humans; Insulin; Leptin; Male; Neuropeptide Y; Valproic Acid	2012
Importance of accurate measurement of carotid intima-media thickness for evaluating epileptic children treated with valproate. Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2013, Volume: 29, Issue:3 Topics: Adiponectin; Anticonvulsants; Carotid Intima-Media Thickness; Epilepsy; Female; Ghrelin; Humans; Leptin; Male; Neuropeptide Y; Valproic Acid	2013
Reply from the authors of the article entitled "Importance of accurate measurement of carotid intima media thickness for evaluating epileptic children treated with valproate". Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2013, Volume: 29, Issue:3 Topics: Adiponectin; Anticonvulsants; Carotid Intima-Media Thickness; Epilepsy; Female; Ghrelin; Humans; Leptin; Male; Neuropeptide Y; Valproic Acid	2013
The effects of topiramate and valproate therapy on insulin, c-peptide, leptin, neuropeptide Y, adiponectin, visfatin, and resistin levels in children with epilepsy. Seizure, 2013, Volume: 22, Issue:10 Topics: Adiponectin; Anticonvulsants; Body Mass Index; Body Weight; C-Peptide; Child; Epilepsy; Female; Fructose; Humans; Insulin; Leptin; Male; Neuropeptide Y; Nicotinamide Phosphoribosyltransferase; Resistin; Topiramate; Valproic Acid	2013
Weight and fat distribution in patients taking valproate: a valproate-discordant gender-matched twin and sibling pair study. Epilepsia, 2014, Volume: 55, Issue:10 Topics: Abdominal Fat; Absorptiometry, Photon; Adult; Anticonvulsants; Blood Pressure; Body Composition; Body Fat Distribution; Diseases in Twins; Epilepsy; Female; Humans; Leptin; Male; Sex Factors; Siblings; Twins, Dizygotic; Twins, Monozygotic; Valproic Acid; Weight Gain	2014
A longitudinal study of the association between the GNB3 C825T polymorphism and metabolic disturbance in bipolar II patients treated with valproate. The pharmacogenomics journal, 2017, Volume: 17, Issue:2 Topics: Adult; Antimanic Agents; Biomarkers; Bipolar Disorder; Body Mass Index; Case-Control Studies; Dyslipidemias; Female; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Heterotrimeric GTP-Binding Proteins; Heterozygote; Homozygote; Humans; Leptin; Lipids; Longitudinal Studies; Male; Middle Aged; Obesity; Pharmacogenomic Variants; Phenotype; Polymorphism, Single Nucleotide; Risk Factors; Time Factors; Treatment Outcome; Valproic Acid; Waist Circumference; Young Adult	2017
Evaluation of adiponectin and leptin levels and oxidative stress in bipolar disorder patients with metabolic syndrome treated by valproic acid. Journal of psychopharmacology (Oxford, England), 2017, Volume: 31, Issue:11 Topics: Adiponectin; Adult; Bipolar Disorder; Humans; Leptin; Male; Metabolic Syndrome; Middle Aged; Oxidative Stress; Risk Factors; Valproic Acid	2017
The effects of valproate and topiramate use on serum insulin, leptin, neuropeptide Y and ghrelin levels in epileptic children. Seizure, 2018, Volume: 58 Topics: Adolescent; Anticonvulsants; Biomarkers; Blood Glucose; Body Mass Index; Child; Epilepsy; Fructose; Ghrelin; Humans; Insulin; Leptin; Neuropeptide Y; Topiramate; Treatment Outcome; Valproic Acid; Weight Gain	2018
The Relationship Between Food Craving, Appetite-Related Hormones and Clinical Parameters in Bipolar Disorder. Nutrients, 2020, Dec-29, Volume: 13, Issue:1 Topics: Acylation; Adult; Anthropometry; Appetite; Bipolar Disorder; Craving; Cross-Sectional Studies; Fast Foods; Female; Ghrelin; Hormones; Humans; Leptin; Male; Middle Aged; Non-Smokers; Obesity; Smokers; Valproic Acid; Weight Gain; Young Adult	2020
The effects of valproate on serum leptin, insulin, and lipid levels in epileptic children. Pediatrics international : official journal of the Japan Pediatric Society, 2021, Volume: 63, Issue:11 Topics: Anticonvulsants; Child; Epilepsy; Humans; Insulin; Leptin; Valproic Acid	2021
Gender and Body Mass Index-Related Serum Level of Adipokines and Metabolic Syndrome Components in Bipolar Patients Who Received Lithium and Valproic Acid. Metabolic syndrome and related disorders, 2022, Volume: 20, Issue:2 Topics: Adipokines; Adiponectin; Bipolar Disorder; Body Mass Index; Cholesterol, HDL; Female; Humans; Leptin; Lithium; Male; Metabolic Syndrome; Obesity; Valproic Acid	2022
Increased growth hormone secretagogue receptor-1a (GHSR-1a) in hypothalamus during olanzapine treatment in rats. Psychoneuroendocrinology, 2022, Volume: 144 Topics: Adiponectin; Animals; Ghrelin; Hypothalamus; Interleukin-6; Leptin; Olanzapine; Rats; Receptors, Ghrelin; Resistin; Tumor Necrosis Factor-alpha; Valproic Acid; Weight Gain	2022