valproic acid has been researched along with lamotrigine in 706 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 73 (10.34) | 18.2507 |
2000's | 282 (39.94) | 29.6817 |
2010's | 254 (35.98) | 24.3611 |
2020's | 97 (13.74) | 2.80 |
Authors | Studies |
---|---|
Bonsignori, A; Colombo, M; Dostert, P; Fariello, RG; Heidempergher, F; McArthur, RA; Pevarello, P; Pinciroli, V; Post, C; Salvati, P; Varasi, M | 1 |
Strassburg, CP; Tukey, RH | 1 |
Topliss, JG; Yoshida, F | 1 |
Bruno-Blanch, L; Gálvez, J; García-Domenech, R | 1 |
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
Huber, VJ; Kwee, IL; Nakada, T; Tsujita, M | 1 |
Brenneman, D; Cuyckens, F; Finley, MF; Herb, M; Huang, Y; Iannucci, R; Klein, B; Leclercq, L; Liu, Y; Lubin, ML; Malatynska, E; Maryanoff, BE; McComsey, DF; Milewski, ME; Parker, MH; Qin, N; Reitz, AB; Smith-Swintosky, VL; White, HS | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC | 1 |
Marona, H; Pękala, E; Szneler, E; Walczak, M; Waszkielewicz, AM | 1 |
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
Brenneman, DE; Finley, MF; Herb, M; Klein, BD; Liu, Y; Lubin, ML; Malatynska, E; Maryanoff, BE; McComsey, DF; Milewski, ME; Parker, MH; Qin, N; Reitz, AB; Smith-Swintosky, VL; White, HS; Wilcox, KS | 1 |
Karcz, T; Karolak-Wojciechowska, J; Kieć-Kononowicz, K; Kuder, K; Latacz, G; Schwed, JS; Stark, H; Łażewska, D | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Land, G; Peck, AW; Weatherley, BC; Yuen, AW | 1 |
O'Donohoe, NV | 1 |
Kelly, KM; Macdonald, RL | 3 |
Buchanan, N | 2 |
Chosidow, O; Duval, X; Francès, C; Herson, S; Lipsker, D; Semah, F | 1 |
Ferrie, CD; Knott, C; Panayiotopoulos, CP; Robinson, RO | 2 |
Buchanan, N; Sharpe, C | 1 |
Ferrie, CD; Panayiotopoulos, CP | 1 |
Di Perri, R; Perucca, E; Pisani, F; Richens, A | 1 |
Duncan, JS; Patsalos, PN; Reutens, DC | 1 |
Alving, J; Besag, FM; Dulac, O; Hosking, G; Spencer, SC; Wallace, SJ | 1 |
Hennessy, MJ; Wiles, CM | 1 |
Aguglia, U; De Sarro, A; De Sarro, G; Nava, F | 1 |
Duncan, JS; Li, LM; O'Donoghue, MF; Russo, M; Sander, JW | 1 |
Boreus, L; Eriksson, AS; Hoppu, K; Nergårdh, A | 1 |
Anderson, GD; Dren, AT; Gidal, BE; Harris, SJ; Lai, AA; Levy, RH; Wargin, WA; Wolf, KB; Yau, MK | 1 |
Jürgens, U; May, TW; Rambeck, B | 2 |
Berger, M; Hesslinger, B; van Calker, D; Walden, J | 1 |
Boas, J; Dam, M; Friis, ML; Gallagher, J; Kristensen, O; Pedersen, B | 1 |
Herranz, JL | 1 |
Bauer, J; Elger, CE; Helmstaedter, C | 1 |
Brodie, MJ; Yuen, AW | 1 |
Mathew, NT | 1 |
Chapman, DP; Giles, WH | 1 |
Connolly, MB; Farrell, K; MacWilliam, LM; Munn, R; Peng, S | 1 |
Kusumakar, V; Yatham, LN | 2 |
Gleichmann, E; Rönnau, AC; Ruzicka, T; Sachs, B; Schuppe, HC; von Schmiedeberg, S | 1 |
Coppola, G; Pascotto, A | 1 |
Chattergoon, DS; Hwang, P; Ito, S; Koren, G; McGuigan, MA | 1 |
Bozinović, D; Dobrić, I; Knezović, I; Loncarić, D; Skerlev, M; Tesović, G; Vukelíc, D | 1 |
Messenheimer, JA; Willmore, LJ | 1 |
Pellock, JM | 1 |
Calabrese, JR; Fatemi, SH; Rapport, DJ; Thuras, P | 1 |
Wallace, SJ | 1 |
Scheen, AJ | 1 |
Bazil, CW; Pedley, TA | 1 |
Isojärvi, JI; Knip, M; Koivunen, R; Myllylä, VV; Pakarinen, AJ; Rättyä, J; Tapanainen, JS; Tekay, A | 1 |
Berlinghieri, MC; David, E; De Sarro, GB; Dominijanni, A; Elia, M; Gulletta, E; Musumeci, SA | 1 |
Anderson, GD | 2 |
Bowden, CL | 4 |
Evans, DL; Murphy, TK; Tueth, MJ | 1 |
Hagan, RM; Xie, X | 1 |
Chang, GY; Gilliam, F; Messenheimer, J; Nyberg, J; Risner, ME; Rudd, GD; Sackellares, JC; Vazquez, B | 1 |
Erfurth, A; Grunze, H | 1 |
Schlienger, RG; Shapiro, LE; Shear, NH | 1 |
Hagan, RM; Higgins, GA; Kirkby, D; Southam, E | 1 |
Donnelly, A; Potter, JM | 1 |
Batty, AB; Black, AB; Harris, AL; Morris, RG; Sallustio, BC | 1 |
Goodwin, FK | 1 |
Böttiger, Y; Ståhle, L; Svensson, JO | 1 |
Chioni, A; Gatzonis, S; Laiaki, A; Mantouvalos, V; Siafakas, A; Zournas, C | 1 |
Lovell, RW | 1 |
Faught, E; French, J; Harden, C; Jacobson, M; Montouris, G; Morris, G; Rosenfeld, W | 1 |
Di Perri, R; Oteri, G; Perucca, E; Pisani, F; Richens, A; Russo, MF | 1 |
Elston, DM | 1 |
Dunn, N; Shakir, S; Wilton, L | 1 |
Brodie, MJ | 1 |
Matsuo, F | 1 |
Mawer, GE; Sander, JW; Wong, IC | 1 |
Bowers, MB; Fazeli, A; Mazure, CM; McKay, BG; Preda, A | 1 |
Boyd, S; Catania, S; Cross, H; de Sousa, C | 1 |
Echaniz-Laguna, A; Hirsch, E; Marescaux, C; Ruolt-Olivesi, I; Thiriaux, A | 1 |
Albani, F; Baruzzi, AA; Contin, M; Riva, R | 1 |
Meyer, MA | 1 |
Jović, NJ; Majkić-Singh, N; Milovanović, DD; Mirković, D | 1 |
Bircher, AJ; Schaub, N | 1 |
Carwile, ST; Husain, AM; Miller, PP; Radtke, RA | 1 |
Chaudron, LH; Jefferson, JW | 1 |
Heynen, T; Krupp, E; Li, XL; Post, RM; Weiss, SR | 1 |
Mojs, E; Toczko, A | 1 |
Pearlstein, T | 1 |
Isojarvi, JI; Tapanainen, JS | 1 |
Frey, M; Kanner, AM | 1 |
Calabrese, JR; Gajwani, P | 1 |
August, PJ; Bhushan, M; Brooke, R; Craven, NM; Hewitt-Symonds, M | 1 |
Anderson, GD; Gidal, BE; Lanning, A; Rutecki, PR; Shaw, R | 1 |
Jozwiak, S; Terczynski, A | 1 |
Karaduman, A; Yalçin, B | 1 |
Aberg, LE; Bäckman, M; Kirveskari, E; Santavuori, P | 1 |
Glauser, TA | 1 |
Harden, CL | 1 |
Allain, H; Biraben, A; Edan, G; Scarabin, JM; Schück, S | 1 |
Kiley, MA; Sander, JW; Smith, SJ | 1 |
Black, AB; Lam, E; Morris, RG; Westley, IS | 1 |
Jagoda, A; Yoon, Y | 1 |
Nemeroff, CB | 1 |
Miura, H | 1 |
Barrett, PS; Biton, V; Hammer, AE; Mirza, W; Montouris, G; Vuong, A | 1 |
Alao, AO; Dewan, MJ | 1 |
Bachański, M; Jóźwiak, S; Karkowska, B; Kmieć, T; Kuczyński, D | 1 |
Berner, A; Gjerstad, L; Isojärvi, JI; Røste, LS; Taubøll, E | 1 |
Betts, T | 1 |
Bartolomei, F; Chauvel, P; Dravet, C; Gastaut, JL; Guye, M | 1 |
Burdick, KE; Goldberg, JF | 1 |
Bowden, CL; Caban, SJ; Calabrese, JR; Kimmel, SE; Rapport, DJ; Shelton, MD; Shirley, ER; Suppes, T | 1 |
McCabe, PH; McNew, CD; Michel, NC | 1 |
Andrews, J; Eadie, MJ; Parker-Scott, S; Reith, DM | 1 |
Perucca, E | 1 |
Brodie, MJ; Dominiczak, M; Kwan, P; Shapiro, D; Stephen, LJ | 1 |
Campellone, JV; Sbei, M | 1 |
Atkinson, SA; Guo, CY; Ronen, GM | 1 |
Ferrier, IN | 1 |
Brodie, MJ; Kwan, P | 1 |
Chan, V; Ilett, KF; Morris, RG; Tett, SE | 1 |
Acquafondata, C; Battaglia, D; Chiricozzi, F; Guzzetta, F; Iuvone, L; Lettori, D; Mittica, A; Pane, M; Stefanini, MC | 1 |
Caban, S; Calabrese, JR; Kimmel, SE; Kujawa, M; Rapport, DJ; Shelton, MD | 1 |
Calabrese, JR; Ketter, TA | 1 |
Aldenkamp, AP; Arends, J; Bootsma, HP; de Vocht, J; Diepman, L; Hulsman, J; Lambrechts, D; Leenen, L; Majoie, M; Schellekens, A | 1 |
Chengappa, KN; Gershon, S; Levine, J | 1 |
Albani, F; Avoni, P; Baruzzi, A; Contin, M; Riva, R | 1 |
Covington, EC | 1 |
De Sarro, A; De Sarro, G; Di Paola, ED; Ferreri, G; Fischer, W | 1 |
Farber, NB; Heinkel, C; Jiang, XP; Nemmers, B | 1 |
Canevini, MP; Canger, R; Cavani, S; Chifari, R; Elia, M; Guerrini, R; Pierluigi, M; Sgrò, V | 1 |
Baraban, SC; Barbaro, NM; Smyth, MD | 1 |
Mataringa, MI; May, TW; Rambeck, B | 1 |
Bauer, G; Deisenhammer, F; Dilitz, E; Luef, G; Niedermüller, U; Thaler, C; Trinka, E; Unterberger, I | 1 |
Armijo, JA; Cuadrado, A; de las Cuevas, I; Valdizán, EM | 1 |
Conn, DK; Robillard, M | 1 |
Baraldo, M; Benetello, P; Furlanut, M; Tonon, A | 1 |
Dodrill, CB | 1 |
Baldwin, D; Bowden, C; Goodwin, G; Grunze, H; Kasper, S; Licht, R; Möller, HJ; Vieta, E | 1 |
Cogulu, O; Gunduz, C; Kultursay, N; Ozkinay, F; Yilmaz, D | 1 |
Rekling, JC | 1 |
Hosák, L; Libiger, J | 1 |
Posner, E | 4 |
Giordano, S; Reed, RC | 1 |
Keck, PE; McElroy, SL | 1 |
Ernst, CL; Goldberg, JF | 1 |
Shelton, RC | 1 |
Keck, PE | 1 |
Biton, V; Hammer, AE; Hoyler, S; Levisohn, P; Vuong, A | 1 |
Keränen, T; Peltola, J; Rainesalo, S; Saransaari, P | 1 |
Bourgeois, BF | 1 |
Freeman, MP; Gelenberg, AJ; Gnanadesikan, M | 1 |
Carandang, CG; Maxwell, DJ; Oesterheld, JR; Robbins, DR | 1 |
Burneo, JG; Faught, E; Knowlton, RC; Kuzniecky, RI; Lawn, N; Limdi, N; Mendez, M; Prasad, A; Welty, TE | 1 |
Ayala, R; Dam, M; Gomez, G; Isojärvi, J; Messenheimer, J; Morrell, MJ; O'Neill, F; Taylor, AE; Tennis, P | 1 |
Fiore, LA; Freitas, A; Thomé-Souza, S; Valente, KD | 1 |
Demiralay, E; Kilinç, M; Söğüt, A; Söğüt, AG; Uzar, H; Yilmaz, A | 1 |
Betts, T; Dutton, N; Greenhill, L; Rolfe, T; Yarrow, H | 1 |
Marson, AG; Mohamed, K; Posner, EB | 3 |
Graham, J; Hitchcock, A; Lander, C; O'Brien, TJ; Vajda, FJ | 1 |
Dittmann, S; Grunze, H | 1 |
Altshuler, LL; Frye, MA; Grunze, H; Keck, P; Kupka, RW; Leverich, GS; McElroy, S; Nolen, WA; Post, RM; Suppes, T; Walden, J | 1 |
Hammer, AE; Kaminow, L; Schimschock, JR; Vuong, A | 1 |
Appleton, RE; Chadwick, DW; Nicolson, A; Smith, DF | 1 |
Gau, CS; Lin, CJ; Liou, HH; Shyu, MK; Wu, SP | 1 |
Gidal, BE; Maloney, K; Parnell, J; Sale, M; Sheth, R | 1 |
Bandara, D; Hashim, N; Ilchyshyn, A; Tan, E | 1 |
Altshuler, L; Cohen, L; Leibenluft, E; Manber, R; Miller, L; Stowe, Z; Suppes, T; Viguera, A; Wisner, KL; Yonkers, KA | 1 |
Meussen-Elholm, ET; Olsen, CM; Røste, LS; Taubøll, E | 1 |
Stahl, SM | 2 |
Chiarelli, F; Cutarella, R; Giannuzzi, R; Latini, G; Morgese, G; Trotta, D; Verrotti, A | 1 |
Beeber, AR; Mueller, TH | 1 |
Kass, E; Klein, RM; Lewis, FT | 1 |
Isojärvi, JI; Mikkonen, K; Päivänsalo, M; Pakarinen, AJ; Tapanainen, P; Vainionpää, LK | 1 |
Ghaemi, SN; Hsu, DJ; Pardo, TB | 1 |
Hammer, AE; Kustra, RP; Messenheimer, JA; Morris, GL | 1 |
Fakhoury, TA; Hammer, AE; Messenheimer, JA; Vuong, A | 1 |
Cerminara, C; Curatolo, P; Montanaro, ML; Seri, S | 1 |
Auricchio, G; Carotenuto, M; Coppola, G; Federico, R; Pascotto, A | 1 |
Baldassano, CF; Ballas, CA; O'Reardon, JP | 1 |
Elger, CE; Helmstaedter, C; Kockelmann, E | 1 |
Becker, OV; Glenn, T; Ketter, TA; Marsh, WK; Rasgon, NL | 1 |
Papp, Z; Török, L | 1 |
Adams, DJ; Bazil, CW; Buchsbaum, R; Du, Y; Hager, M; Hirsch, LJ; Morrell, MJ; Resor, SR; Spencer, HT; Straka, T; Weintraub, D | 1 |
Battino, D; Perucca, E; Tomson, T | 1 |
Buchan, S; Kerr, MP; Morgan, CL | 1 |
Oral, ET; Vahip, S | 1 |
Cook, M; Eadie, M; Graham, J; Hitchcock, A; Lander, C; O'brien, T; Solinas, C; Vajda, F | 1 |
Goodwin, FK; Lieberman, DZ | 1 |
Frediani, F | 1 |
Karlov, VA | 1 |
Schatzberg, AF | 1 |
Pedersen, AM; Rasmussen, NH | 1 |
Mishchenko, AL; Morozov, GV; Semenova, NV; Slastenko, OA | 1 |
Bebin, EM; Burneo, JG; Miller, S; Prasad, A | 1 |
Biton, V; Blum, D; Hammer, AE; Messenheimer, JA; Natarajan, S; Sale, ME; Vuong, A | 1 |
Ahmad, S; Fowler, LJ; Whitton, PS | 1 |
Arban, R; Brackenborough, K; Gerrard, P; Large, C; Maraia, G; Wilson, A; Winyard, L | 1 |
Pucci, V; Raggi, MA | 1 |
Flück, CE; Miller, WL; Yaworsky, DC | 1 |
Dam, M; P-Codrea Tigaran, S; Sidenius, P | 1 |
De Simone, C; Famularo, G; Minisola, G | 1 |
Curtis, V | 1 |
Gaily, E; Penovich, P | 1 |
Bilali, S; Calabrese, JR; Findling, RL; Jackson, K; Rapport, DJ; Youngstrom, EA | 1 |
Brodie, MJ; Mohanraj, R | 1 |
Messenheimer, J; Mockenhaupt, M; Schlingmann, J; Tennis, P | 1 |
Calabrese, JR; Elhaj, O; Gajwani, P; Gao, K; Muzina, DJ | 1 |
Fein, JD; Hamann, KL | 1 |
Negosanti, F; Neri, I; Patrizi, A; Posar, A; Santucci, M; Savoia, F | 1 |
Anderson, GD; Shen, DD; Szot, P; White, SS | 1 |
Haider, N; Rahman, M | 1 |
Gidal, BE; Hammer, A; Tamura, T; Vuong, A | 1 |
Solinas, C; Vajda, FJ | 1 |
Alda, M; Baruch, P; Beaulieu, S; Connolly, M; Daigneault, A; Gorman, CP; Kennedy, SH; MacQueen, G; McIntyre, R; Milev, R; O'Donovan, C; Parikh, S; Ravindran, A; Schaffer, A; Sharma, V; Silverstone, P; Yatham, LN; Young, LT | 1 |
Amann, B; Calabrese, JR; Elhaj, O; Forsthoff, A; Gajwani, P; Gao, K; Grunze, H; Muzina, D | 1 |
Jagadheesan, K; Sinha, VK; Thakur, A | 1 |
Howland, RH | 1 |
Deckers, CL; Egberts, AC; Hekster, YA; Keyser, A; Knoester, PD; Renier, WO | 1 |
Berry, D; Millington, C | 1 |
Andrews, G; Page, AC | 1 |
Chan, YC; Hankins, MB; Miller, KM; Shaheen, N; Votolato, NA | 1 |
Steinborn, B | 1 |
Alvey, CW; Bockbrader, HN; Brodie, MJ; Bron, NJ; Gibson, GL; Hounslow, NJ; Posvar, EL; Randinitis, EJ; Wesche, DL; Wilson, EA | 1 |
Baldy-Moulinier, M; Berramdane, M; Coubes, P; Crespel, A; Gelisse, P; Genton, P; Monicard, C | 1 |
Chang, CC; Chang, HA; Huang, SY; Shiah, IS | 1 |
Bergmann, L; Kurlemann, G; Schmitz, B; Siemes, H; Steinhoff, BJ; Ueberall, MA | 1 |
Benbadis, SR | 1 |
Namushi, RN; Otaiku, OM; Saravanan, N | 1 |
Belousova, ED; Dorofeeva, MIu; Ermakov, AIu | 1 |
Ab Rahman, AF; Ibrahim, MI; Ismail, HI; Seng, TB | 1 |
Auricchio, G; Coppola, G; Epifanio, G; Federico, RR; Pascotto, A; Resicato, G | 1 |
Durst, R; Raskin, S; Teitelbaum, A; Zislin, J | 1 |
Antai-Otong, D | 1 |
Stefan, H; Tilz, C; Tilz, GP; Wang, B; Wang-Tilz, Y | 1 |
Khadse, SS; Khanna, SA; Mittal, G; Surve, TY | 1 |
Dickinson, RG; Elliot, DJ; Mackenzie, PI; Miners, JO; Rowland, A; Williams, JA | 1 |
Alldredge, B; Fenn, HH; Ketter, TA; Sommer, BR | 1 |
Benabarre, A; Colom, F; Comes, M; Daban, C; Goikolea, JM; Martínez-Arán, A; Sánchez-Moreno, J; Torrent, C; Vieta, E | 1 |
Bowden, CL; Karren, NU | 1 |
Ginsberg, LD | 1 |
Kapaki, E; Limpitaki, G; Paraskevas, GP; Petropoulou, O; Triantafyllou, NI; Vassilopoulos, D | 1 |
Altmann, A; Bessenyei, M; Clemens, B; Hollódy, K; Jerney, J; Kollár, K; Ménes, A; Piros, P; Rosdy, B; Rózsavölgyi, M; Steinecker, K | 1 |
Bóné, B; Janszky, J | 1 |
Baker, GA; Finnell, RH; Kalayjian, LA; Liporace, JD; Loring, DW; Mawer, G; Meador, KJ; Pennell, PB; Smith, JC; Wolff, MC | 1 |
Atagun, I; Kaya, MC; Kurt, E; Oral, ET; Savas, E; Savas, HA; Selek, S; Yumru, M | 1 |
Chou, JC; Fazzio, L | 1 |
Luef, G; Ohman, I; Pittschieler, S; Sabers, A; Tomson, T | 1 |
Crespel, A; Gélisse, P | 1 |
Guillon, B; Maiga, Y; Nogues, B | 1 |
Steinhoff, BJ | 1 |
Bowden, CL; Jamison, KL; Redmond, JR | 1 |
Beaulieu, S; Kennedy, SH; MacQueen, G; McIntyre, RS; O'Donovan, C; Parikh, SV; Sharma, V; Yatham, LN | 1 |
Cui, J; Shao, L; Wang, JF; Young, LT | 1 |
Akin, R; Gok, F; Gokcay, E; Kurt, I; Sarici, SU; Unay, B | 1 |
Crespel, A; Gelisse, P; Genton, P | 1 |
Choi, KG; Chung, HW; Kim, SH; Lee, HW; Lee, JW | 1 |
Bahk, WM; Chae, JH; Jun, TY; Woo, YS | 1 |
Ben-Ezra, J; Massey, GV; Riley, RS; Russell, EC; Williams, DC | 1 |
Piantino, JA; Torres, A | 1 |
Calabrese, JR; Colangelo, E; Manning, JS; Muzina, DJ | 1 |
Bialer, M; Chien, S; Doose, DR; Mertens, A; Novak, G; Solanki, B; Verhaeghe, T; Yao, C | 1 |
Hasegawa, R; Hirata-Koizumi, M; Miyake, S; Saito, M | 1 |
Al-Kharusi, AM; Alwaidh, M; Appleton, R; Baker, GA; Chadwick, DW; Cockerell, OC; Cooper, PN; Cramp, C; Doughty, J; Eaton, B; Gamble, C; Goulding, PJ; Howell, SJ; Hughes, A; Jackson, M; Jacoby, A; Kellett, M; Lawson, GR; Leach, JP; Marson, AG; Nicolaides, P; Roberts, R; Shackley, P; Shen, J; Smith, CT; Smith, DF; Smith, PE; Vanoli, A; Williamson, PR | 1 |
Bajbouj, M; Danker-Hopfe, H; Gallinat, J; Hellen, F; Lang, UE; Lisanby, SH; Neu, P; Vesper, J | 1 |
Cander, B; Girisgin, SA; Gul, M; Kaya, E; Kaya, H; Kocak, S | 1 |
Alda, M; Duffy, A; Garnham, J; Macdougall, M; Munro, A; O'Donovan, C; Passmore, M; Slaney, C; Teehan, A | 1 |
Bourin, M; Prica, C | 1 |
Feucht, M; Hall, RE; Kindler, J; Mayer, H; Pahs, G; Plattner, B; Steiner, H; Williams, RP | 1 |
Reimers, A; Skogvoll, E; Spigset, O; Sund, JK | 1 |
Amann, B; Grunze, H; Trimble, M; Vieta, E | 1 |
Bodard, S; Castelnau, P; Chalon, S; Gressens, P; Lagrue, E; Saliba, E | 1 |
Brodie, MJ; Butler, E; Hitiris, N; Leach, JP; Leach, VM; Parker, P; Sills, GJ; Stephen, LJ; Wilson, EA | 1 |
Kim, JY; Lee, HW | 1 |
Edelbroek, PM; Vermeij, TA | 1 |
Correa, H; da Rocha, FF; Soares, FM; Teixeira, AL | 1 |
Bilali, SR; Calabrese, JR; Elhaj, O; Ganocy, SJ; Rapport, DJ; Sajatovic, M; Youngstrom, EA | 1 |
Grunze, H | 1 |
De Smedt, H; Otoul, C; Stockis, A | 1 |
Cross, H; Ferrie, C; Lascelles, K; Livingston, J; Mewasingh, L | 1 |
Graham, J; Kaye, NS; Nanry, K; Roberts, J; Thompson, T | 1 |
Baumann, RJ; Fakhoury, TA; Hammer, AE; Kustra, RP; Messenheimer, JA; Vuong, A | 1 |
Greenshaw, AJ; McGrath, BM; McKay, R; Silverstone, PH; Slupsky, CM | 1 |
Appleton, R; Baker, GA; Chadwick, DW; Doughty, J; Eaton, B; Gamble, C; Jacoby, A; Marson, AG; Shackley, P; Smith, DF; Tudur-Smith, C; Vanoli, A; Williamson, PR | 1 |
Barbieri, M; Beynon, S; Bravo Vergel, Y; Duffy, S; Dunn, G; Geddes, J; Gilbody, S; Palmer, S; Soares-Weiser, K; Woolacott, N | 1 |
Auvinen, A; Keränen, T; Kharazmi, E; Peltola, J; Peltola, M; Raitanen, J | 1 |
Borgohain, R; Evers, S; Guekht, AB; Karlov, VA; Lee, BI; Messenheimer, JA; Naritoku, DK; Pohl, LR; Warnock, CR | 1 |
Bauer, J; Buchmüller, L; Burr, W; Reuber, M | 1 |
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Amuan, ME; Henion, A; Lopez, MR; Panahi, S; Pugh, MJ; VanCott, AC | 1 |
Božina, N; Domjanović, IK; Gadže, ŽP; Ganoci, L; Lovrić, M; Romić, ZČ; Šimičević, L; Sporiš, IŠ; Trkulja, V | 1 |
Akyol, A; Apaydın-Dogan, E; Aslan-Kara, K; Ataklı, D; Atalar, AC; Baykan, B; Bebek, N; Bican-Demir, A; Bicer-Gomceli, Y; Bora, İ; Bozdemir, H; Cakmak, G; Ceyhan-Dirican, A; Delil, S; Erdinc, O; Eren, F; Ersoy, A; Genc, F; Gul, G; Gul, ZB; Gurses, C; Halac, G; Ilhan-Algin, D; Kamisli, O; Keskin-Guler, S; Kutlu, G; Mısırlı, CH; Ozkara, C; Pekoz, MT; Sarı, H; Saygi, S; Tantik-Pak, A; Tekin, B; Tezer-Fılık, I; Tutkavul, K; Ustun-Ozek, S; Velioglu, SK; Yalcın, AD; Yeni, SN; Yücel, SP | 1 |
Hume, AL; Lawal, OD; Meador, KJ; Wen, X | 1 |
Eadie, M; Graham, J; Hitchcock, A; Lander, C; O'Brien, T; Perucca, P; Vajda, F | 1 |
162 review(s) available for valproic acid and lamotrigine
Article | Year |
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Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic | 2000 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Mechanisms of action of currently prescribed and newly developed antiepileptic drugs.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Drugs, Investigational; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Ion Channels; Lamotrigine; Mice; Phenylcarbamates; Propylene Glycols; Rats; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Triazines; Valproic Acid | 1994 |
Antiepileptic drug mechanisms of action.
Topics: Acetates; Action Potentials; Amines; Anticonvulsants; Calcium Channels; Cyclohexanecarboxylic Acids; Drug Design; Epilepsy, Generalized; Gabapentin; gamma-Aminobutyric Acid; Humans; Ion Channels; Lamotrigine; Receptors, GABA-A; Receptors, Neurotransmitter; Sodium Channels; Triazines; Valproic Acid | 1993 |
Antiepileptic drug mechanisms of action.
Topics: Acetates; Action Potentials; Amines; Animals; Anticonvulsants; Barbiturates; Benzodiazepines; Calcium Channels; Carbamazepine; Central Nervous System; Cyclohexanecarboxylic Acids; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Ion Channels; Lamotrigine; Phenytoin; Rats; Receptors, GABA; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Sodium Channels; Triazines; Trimethadione; Valproic Acid; Vigabatrin | 1995 |
[Advantages and disadvantages of new antiepileptic drugs].
Topics: Acetates; Adrenocorticotropic Hormone; Amines; Anticonvulsants; Brain; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Phenylcarbamates; Propylene Glycols; Triazines; Valproic Acid; Vigabatrin | 1996 |
Pharmacologic and dietary therapies in epilepsy: conventional treatments and recent advances.
Topics: Acetates; Amines; Anticonvulsants; Benzodiazepines; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Ketone Bodies; Lamotrigine; Phenylcarbamates; Phenytoin; Propylene Glycols; Triazines; Valproic Acid; Vigabatrin | 1997 |
Adult experience with lamotrigine.
Topics: Adult; Anticonvulsants; Drug Interactions; Epilepsy; Humans; Lamotrigine; Treatment Outcome; Triazines; Valproic Acid | 1997 |
Overview of lamotrigine and the new antiepileptic drugs: the challenge.
Topics: Acetates; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Drug Interactions; Epilepsy; Exanthema; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Phenylcarbamates; Propylene Glycols; Tiagabine; Treatment Outcome; Triazines; Valproic Acid; Vigabatrin | 1997 |
Myoclonus and epilepsy in childhood: a review of treatment with valproate, ethosuximide, lamotrigine and zonisamide.
Topics: Anticonvulsants; Child; Child, Preschool; Epilepsies, Myoclonic; Ethosuximide; Humans; Infant; Isoxazoles; Lamotrigine; Triazines; Valproic Acid; Zonisamide | 1998 |
Advances in the medical treatment of epilepsy.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Diazepam; Drug Approval; Drug Design; Drug Interactions; Drug Resistance; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Injections, Intravenous; Ketones; Lamotrigine; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Phenylcarbamates; Phenytoin; Prodrugs; Propylene Glycols; Tiagabine; Topiramate; Triazines; United States; Valproic Acid; Vigabatrin | 1998 |
A mechanistic approach to antiepileptic drug interactions.
Topics: Acetates; Amines; Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Carbamazepine; Cyclohexanecarboxylic Acids; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Induction; Ethosuximide; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Glucuronosyltransferase; Humans; Lamotrigine; Mixed Function Oxygenases; Nipecotic Acids; Phenobarbital; Phenylcarbamates; Phenytoin; Propylene Glycols; Tiagabine; Topiramate; Triazines; Valproic Acid; Vigabatrin | 1998 |
New concepts in mood stabilization: evidence for the effectiveness of valproate and lamotrigine.
Topics: Affect; Anticonvulsants; Humans; Lamotrigine; Mood Disorders; Triazines; Valproic Acid | 1998 |
Special considerations: use of lithium in children, adolescents, and elderly populations.
Topics: Abnormalities, Drug-Induced; Acetates; Adolescent; Adult; Age Factors; Aged; Amines; Anticonvulsants; Bipolar Disorder; Carbamazepine; Child; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Lithium; Male; Pregnancy; Triazines; Valproic Acid | 1998 |
Cellular and molecular actions of lamotrigine: Possible mechanisms of efficacy in bipolar disorder.
Topics: Acetates; Action Potentials; Amines; Anticonvulsants; Antidepressive Agents; Antimanic Agents; Bipolar Disorder; Calcium Channel Blockers; Carrier Proteins; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Ion Channel Gating; Lamotrigine; Limbic System; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Neural Inhibition; Neuronal Plasticity; Serotonin Plasma Membrane Transport Proteins; Signal Transduction; Sodium Channels; Synaptic Transmission; Triazines; Valproic Acid | 1998 |
Lamotrigine-induced severe cutaneous adverse reactions.
Topics: Adolescent; Adult; Age Factors; Aged; Anticonvulsants; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Female; Humans; Lamotrigine; Male; Middle Aged; Stevens-Johnson Syndrome; Triazines; Valproic Acid | 1998 |
Anticonvulsant therapy and suicide risk in affective disorders.
Topics: Amitriptyline; Anticonvulsants; Bipolar Disorder; Carbamazepine; Double-Blind Method; Female; Follow-Up Studies; Humans; Lamotrigine; Lithium; Male; Mood Disorders; Prospective Studies; Risk Factors; Suicide; Suicide Prevention; Triazines; Valproic Acid | 1999 |
Monostars: an aid to choosing an antiepileptic drug as monotherapy.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Oxcarbazepine; Phenobarbital; Phenytoin; Practice Guidelines as Topic; Practice Patterns, Physicians'; Triazines; Valproic Acid; Vigabatrin | 1999 |
Lamotrigine.
Topics: Adolescent; Adult; Animals; Anticonvulsants; Child; Clinical Trials as Topic; Diplopia; Dizziness; Drug Administration Schedule; Drug Eruptions; Drug Interactions; Drug Prescriptions; Drug Therapy, Combination; Epilepsy; Headache; Humans; Lamotrigine; Practice Guidelines as Topic; Product Surveillance, Postmarketing; Treatment Outcome; Triazines; Valproic Acid | 1999 |
Mood stabilizers during breastfeeding: a review.
Topics: Acetates; Amines; Anticonvulsants; Bipolar Disorder; Breast Feeding; Carbamazepine; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant; Infant, Newborn; Lamotrigine; Lithium; MEDLINE; Milk, Human; Pregnancy; Pregnancy Complications; Puerperal Disorders; Triazines; Valproic Acid | 2000 |
Antidepressant treatment of posttraumatic stress disorder.
Topics: Anticonvulsants; Antidepressive Agents; Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Double-Blind Method; Humans; Lamotrigine; Lithium; Monoamine Oxidase Inhibitors; Placebos; Selective Serotonin Reuptake Inhibitors; Sertraline; Stress Disorders, Post-Traumatic; Treatment Outcome; Triazines; Valproic Acid | 2000 |
Idiosyncratic reactions: new methods of identifying high-risk patients.
Topics: Anticonvulsants; Biomarkers; Drug Monitoring; Epilepsy; Epoxide Hydrolases; Felbamate; Free Radical Scavengers; Genetic Markers; Humans; Lamotrigine; Phenylcarbamates; Propylene Glycols; Risk Factors; Triazines; Valproic Acid | 2000 |
Therapeutic safety monitoring: what to look for and when to look for it.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Monitoring; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Phenobarbital; Phenytoin; Practice Guidelines as Topic; Topiramate; Triazines; Valproic Acid; Vigabatrin | 2000 |
New antiepileptic drugs and preparations.
Topics: Acetates; Administration, Rectal; Age Factors; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Diazepam; Drug Overdose; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Injections, Intravenous; Lamotrigine; Phenylcarbamates; Phenytoin; Propylene Glycols; Topiramate; Triazines; Valproic Acid | 2000 |
An ever-increasing pharmacopoeia for the management of patients with bipolar disorder.
Topics: Acetates; Amines; Anticonvulsants; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Carbamazepine; Clozapine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Electroconvulsive Therapy; Electromagnetic Phenomena; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Lithium; Olanzapine; Pirenzepine; Risperidone; Topiramate; Treatment Outcome; Triazines; Valproic Acid | 2000 |
Novel treatments for bipolar disorder.
Topics: Acetates; Amines; Bipolar Disorder; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Fatty Acids, Omega-3; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Topiramate; Triazines; Valproic Acid | 2001 |
Cognitive side effects of anticonvulsants.
Topics: Acetates; Amines; Anticonvulsants; Bipolar Disorder; Carbamazepine; Cognition Disorders; Cyclohexanecarboxylic Acids; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Mood Disorders; Topiramate; Triazines; Valproic Acid | 2001 |
Bipolar rapid cycling: focus on depression as its hallmark.
Topics: Anticonvulsants; Antidepressive Agents, Tricyclic; Bipolar Disorder; Comorbidity; Controlled Clinical Trials as Topic; Depressive Disorder; Drug Therapy, Combination; Humans; Lamotrigine; Lithium; Patient Compliance; Placebos; Substance-Related Disorders; Survival Analysis; Treatment Outcome; Triazines; Valproic Acid | 2001 |
The management of refractory idiopathic epilepsies.
Topics: Adolescent; Anticonvulsants; Child; Clinical Protocols; Drug Administration Schedule; Drug Therapy, Combination; Epilepsies, Partial; Epilepsy; Epilepsy, Generalized; Fructose; Humans; Lamotrigine; Topiramate; Treatment Outcome; Triazines; Valproic Acid | 2001 |
Developments in mood stabilisers.
Topics: Anticonvulsants; Antidepressive Agents; Antipsychotic Agents; Bipolar Disorder; Carbamazepine; Electroconvulsive Therapy; Electromagnetic Fields; Fructose; Humans; Lamotrigine; Lithium; Nipecotic Acids; Psychotherapy; Suicide Prevention; Thyroxine; Tiagabine; Topiramate; Triazines; Valproic Acid | 2001 |
Current research on rapid cycling bipolar disorder and its treatment.
Topics: Acute Disease; Antimanic Agents; Bipolar Disorder; Carbamazepine; Drug Administration Schedule; Drug Therapy, Combination; Humans; Lamotrigine; Lithium Carbonate; Morbidity; Prognosis; Recurrence; Severity of Illness Index; Thyroid Hormones; Triazines; Valproic Acid | 2001 |
Stabilization of mood from below versus above baseline in bipolar disorder: a new nomenclature.
Topics: Affect; Antidepressive Agents; Antipsychotic Agents; Bipolar Disorder; Carbamazepine; Clinical Trials as Topic; Double-Blind Method; Electroconvulsive Therapy; Humans; Lamotrigine; Lithium; Models, Psychological; Terminology as Topic; Treatment Outcome; Triazines; Valproic Acid | 2002 |
The evolving role of topiramate among other mood stabilizers in the management of bipolar disorder.
Topics: Acetates; Acute Disease; Amines; Anticonvulsants; Antimanic Agents; Bipolar Disorder; Carbamazepine; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Lithium; Randomized Controlled Trials as Topic; Topiramate; Triazines; Valproic Acid | 2001 |
Anticonvulsants for neuropathic pain and detoxification.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Clonazepam; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Inactivation, Metabolic; Lamotrigine; Neuralgia; Phenytoin; Substance Withdrawal Syndrome; Triazines; Valproic Acid | 1998 |
Children versus adults: pharmacokinetic and adverse-effect differences.
Topics: Adolescent; Age Factors; Anticonvulsants; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Eruptions; Epilepsy; Exanthema; Female; Humans; Infant; Infant, Newborn; Lamotrigine; Liver Diseases; Male; Risk Factors; Triazines; Valproic Acid | 2002 |
World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for biological treatment of bipolar disorders. Part I: Treatment of bipolar depression.
Topics: Antidepressive Agents; Antimanic Agents; Biological Psychiatry; Bipolar Disorder; Carbamazepine; Electroconvulsive Therapy; Evidence-Based Medicine; Humans; International Cooperation; Lamotrigine; Lithium Carbonate; Triazines; Valproic Acid | 2002 |
Antiepileptic drugs in schizophrenia: a review.
Topics: Anticonvulsants; Antipsychotic Agents; Carbamazepine; Drug Resistance; Humans; Lamotrigine; Receptors, GABA; Schizophrenia; Synaptic Transmission; Triazines; Valproic Acid | 2002 |
Absence seizures in children.
Topics: Acetates; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Epilepsy, Absence; Ethosuximide; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Triazines; Valproic Acid | 2002 |
New approaches in managing bipolar depression.
Topics: Anticonvulsants; Antidepressive Agents; Antipsychotic Agents; Bipolar Disorder; Carbamazepine; Clinical Trials as Topic; Drug Administration Schedule; Drug Therapy, Combination; Humans; Lamotrigine; Lithium; Treatment Outcome; Triazines; Valproic Acid | 2003 |
Antidepressant properties of anticonvulsant drugs for bipolar disorder.
Topics: Acetates; Affect; Amines; Anticonvulsants; Antidepressive Agents; Bipolar Disorder; Carbamazepine; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Lithium; Topiramate; Triazines; Valproic Acid | 2003 |
Treating bipolar depression.
Topics: Acetates; Affect; Amines; Anticonvulsants; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Carbamazepine; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Lithium Compounds; Nipecotic Acids; Olanzapine; Oxcarbazepine; Pirenzepine; Tiagabine; Topiramate; Treatment Outcome; Triazines; Valproic Acid; Zonisamide | 2003 |
Long-term therapy of bipolar illness.
Topics: Affect; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Carbamazepine; Controlled Clinical Trials as Topic; Humans; Lamotrigine; Lithium Compounds; Olanzapine; Pirenzepine; Secondary Prevention; Time Factors; Treatment Outcome; Triazines; Valproic Acid | 2003 |
Chronic management of seizures in the syndromes of idiopathic generalized epilepsy.
Topics: Adult; Anticonvulsants; Child; Clinical Trials as Topic; Epilepsy, Generalized; Fructose; Humans; Lamotrigine; Syndrome; Topiramate; Treatment Outcome; Triazines; Valproic Acid | 2003 |
Valproate.
Topics: Antimanic Agents; Bipolar Disorder; Drug Interactions; Humans; Lamotrigine; Lithium Compounds; Prognosis; Randomized Controlled Trials as Topic; Triazines; Valproic Acid; Weight Gain | 2003 |
Alternatives to lithium and divalproex in the maintenance treatment of bipolar disorder.
Topics: Acetates; Amines; Anticonvulsants; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Calcium Channel Blockers; Carbamazepine; Clozapine; Cyclohexanecarboxylic Acids; Dibenzothiazepines; Donepezil; Fatty Acids, Omega-3; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Indans; Lamotrigine; Lithium Carbonate; Olanzapine; Piperazines; Piperidines; Pirenzepine; Quetiapine Fumarate; Risperidone; Thiazoles; Topiramate; Treatment Outcome; Triazines; Valproic Acid | 2003 |
Ethosuximide, sodium valproate or lamotrigine for absence seizures in children and adolescents.
Topics: Adolescent; Anticonvulsants; Child; Epilepsy, Absence; Ethosuximide; Humans; Lamotrigine; Randomized Controlled Trials as Topic; Triazines; Valproic Acid | 2003 |
[Treatment of acute bipolar disorder. Intriguing balancing act between mania and depression].
Topics: Acute Disease; Algorithms; Antidepressive Agents; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Carbamazepine; Drug Therapy, Combination; Humans; Isotopes; Lamotrigine; Lithium; Olanzapine; Pirenzepine; Risperidone; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Triazines; Valproic Acid | 2003 |
A re-evaluation of the role of antidepressants in the treatment of bipolar depression: data from the Stanley Foundation Bipolar Network.
Topics: Adult; Affect; Antidepressive Agents; Bipolar Disorder; Depressive Disorder; Double-Blind Method; Drug Administration Schedule; Female; Foundations; Humans; Lamotrigine; Male; Monoamine Oxidase Inhibitors; Morbidity; Prospective Studies; Randomized Controlled Trials as Topic; Recurrence; Retrospective Studies; Time Factors; Triazines; Valproic Acid | 2003 |
Management of bipolar disorder during pregnancy and the postpartum period.
Topics: Adolescent; Adult; Anticonvulsants; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Carbamazepine; Embryonic and Fetal Development; Female; Fetal Diseases; Humans; Lamotrigine; Lithium Carbonate; Postpartum Period; Pregnancy; Prenatal Exposure Delayed Effects; Triazines; Valproic Acid | 2004 |
Anticonvulsants as anxiolytics, part 1: tiagabine and other anticonvulsants with actions on GABA.
Topics: Anti-Anxiety Agents; Anticonvulsants; Anxiety Disorders; Carbamazepine; Fructose; GABA Agonists; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Synapses; Tiagabine; Topiramate; Triazines; Valproic Acid | 2004 |
An overview of primary care assessment and management of bipolar disorder.
Topics: Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Diagnostic Errors; Humans; Lamotrigine; Lithium; Olanzapine; Primary Health Care; Triazines; Valproic Acid | 2004 |
Strategies for preventing the recurrence of bipolar disorder.
Topics: Anticonvulsants; Antidepressive Agents; Benzodiazepines; Bipolar Disorder; Cognitive Behavioral Therapy; Combined Modality Therapy; Drug Therapy, Combination; Humans; Lamotrigine; Lithium; Olanzapine; Patient Education as Topic; Psychotherapy; Secondary Prevention; Selective Serotonin Reuptake Inhibitors; Triazines; Valproic Acid | 2004 |
Rethinking the treatment paradigm for bipolar depression: the importance of long-term management.
Topics: Amines; Anticonvulsants; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Carbamazepine; Chronic Disease; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Lithium Carbonate; Randomized Controlled Trials as Topic; Time; Topiramate; Triazines; Valproic Acid | 2004 |
Correlating lamotrigine serum concentrations with tolerability in patients with epilepsy.
Topics: Anticonvulsants; Dose-Response Relationship, Drug; Drug Eruptions; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Gastrointestinal Diseases; Headache; Humans; Lamotrigine; Male; Mental Disorders; Nervous System Diseases; Retrospective Studies; Sleep Initiation and Maintenance Disorders; Triazines; Valproic Acid | 2004 |
Bipolar depression: an overview.
Topics: Acute Disease; Antidepressive Agents; Antimanic Agents; Benzodiazepines; Bipolar Disorder; Chemoprevention; Contraindications; Depressive Disorder; Diagnosis, Differential; Drug Therapy, Combination; Humans; Lamotrigine; Lithium; Olanzapine; Triazines; Valproic Acid | 2004 |
Separate and concomitant use of lamotrigine, lithium, and divalproex in bipolar disorders.
Topics: Acute Disease; Administration, Oral; Antimanic Agents; Bipolar Disorder; Drug Therapy, Combination; Humans; Lamotrigine; Lithium Carbonate; Prognosis; Treatment Outcome; Triazines; Valproic Acid | 2004 |
Anticonvulsant drugs in primary headaches prophylaxis.
Topics: Amines; Anticonvulsants; Carbamazepine; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-Aminobutyric Acid; Headache; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Oxcarbazepine; Piracetam; Topiramate; Triazines; Valproic Acid; Vigabatrin; Zonisamide | 2004 |
[Therapy of epilepsy: current strategy and tactics].
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Age Factors; Anticonvulsants; Carbamazepine; Child; Drug Therapy, Combination; Epilepsy; Female; Fetus; Humans; Infant, Newborn; Lamotrigine; Male; Polycystic Ovary Syndrome; Pregnancy; Risk Factors; Sex Factors; Triazines; Valproic Acid | 2004 |
Employing pharmacologic treatment of bipolar disorder to greatest effect.
Topics: Anticonvulsants; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Lamotrigine; Lithium; Olanzapine; Receptors, GABA; Receptors, Glutamate; Treatment Outcome; Triazines; Valproic Acid | 2004 |
Absence seizures in children.
Topics: Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Epilepsy, Absence; Ethosuximide; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Triazines; Valproic Acid | 2003 |
[Childhood and juvenile absence epilepsy. Treatment and prognosis].
Topics: Anticonvulsants; Child; Child Development; Child, Preschool; Cognition; Epilepsy, Absence; Ethosuximide; Evidence-Based Medicine; Humans; Lamotrigine; Prognosis; Triazines; Valproic Acid | 2004 |
Absence seizures in children.
Topics: Adolescent; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Epilepsy, Absence; Ethosuximide; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Triazines; Valproic Acid | 2004 |
A systematic review of treatment of typical absence seizures in children and adolescents with ethosuximide, sodium valproate or lamotrigine.
Topics: Anticonvulsants; Child; Epilepsy, Absence; Ethosuximide; Humans; Lamotrigine; Randomized Controlled Trials as Topic; Triazines; Valproic Acid | 2005 |
Analysis of antiepileptic drugs in biological fluids by means of electrokinetic chromatography.
Topics: Acetazolamide; Anticonvulsants; Barbiturates; Benzodiazepines; Carbamazepine; Chromatography, Micellar Electrokinetic Capillary; Felbamate; Humans; Hydantoins; Isoxazoles; Lamotrigine; Phenylcarbamates; Propylene Glycols; Succinimides; Triazines; Valproic Acid; Vigabatrin; Zonisamide | 2005 |
Women are not the same as men: specific clinical issues for female patients with bipolar disorder.
Topics: Anticonvulsants; Antidepressive Agents; Benzodiazepines; Bipolar Disorder; Counseling; Dibenzothiazepines; Family Planning Services; Female; Humans; Lamotrigine; Lithium Carbonate; Male; Olanzapine; Pregnancy; Pregnancy Complications; Quetiapine Fumarate; Risperidone; Teratogens; Triazines; Valproic Acid; Women's Health | 2005 |
New data on the use of lithium, divalproate, and lamotrigine in rapid cycling bipolar disorder.
Topics: Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Humans; Lamotrigine; Lithium Carbonate; Periodicity; Randomized Controlled Trials as Topic; Triazines; Valproic Acid | 2005 |
Lamotrigine and antiepileptic drugs as mood stabilizers in bipolar disorder.
Topics: Acute Disease; Amines; Anticonvulsants; Antimanic Agents; Bipolar Disorder; Carbamazepine; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Oxcarbazepine; Randomized Controlled Trials as Topic; Secondary Prevention; Triazines; Valproic Acid | 2005 |
Canadian Network for Mood and Anxiety Treatments (CANMAT) guidelines for the management of patients with bipolar disorder: consensus and controversies.
Topics: Adolescent; Adult; Age of Onset; Anticonvulsants; Antipsychotic Agents; Anxiety Disorders; Benzodiazepines; Bipolar Disorder; Canada; Chronic Disease; Comorbidity; Diagnostic and Statistical Manual of Mental Disorders; Drug Monitoring; Female; Humans; Lamotrigine; Lithium Carbonate; Mass Screening; Mood Disorders; Olanzapine; Personality Disorders; Prevalence; Quality of Life; Risk Factors; Substance-Related Disorders; Triazines; Valproic Acid | 2005 |
Antiepileptic drugs in mood-disordered patients.
Topics: Anticonvulsants; Bipolar Disorder; Carbamazepine; Depressive Disorder; Humans; Lamotrigine; Treatment Outcome; Triazines; Valproic Acid | 2005 |
Anticonvulsant drug therapies.
Topics: Amines; Anticonvulsants; Bipolar Disorder; Carbamazepine; Cyclohexanecarboxylic Acids; Depressive Disorder; Drug Administration Schedule; Drug Interactions; Drug Monitoring; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Nurse's Role; Oxcarbazepine; Patient Selection; Safety; Topiramate; Treatment Outcome; Triazines; Valproic Acid; Zonisamide | 2005 |
Absence seizures in children.
Topics: Adolescent; Amines; Anticonvulsants; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Epilepsy, Absence; Ethosuximide; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Triazines; Valproic Acid | 2005 |
Ethosuximide, sodium valproate or lamotrigine for absence seizures in children and adolescents.
Topics: Adolescent; Anticonvulsants; Child; Epilepsy, Absence; Ethosuximide; Humans; Lamotrigine; Randomized Controlled Trials as Topic; Triazines; Valproic Acid | 2005 |
Practical management issues for idiopathic generalized epilepsies.
Topics: Age Factors; Age of Onset; Anticonvulsants; Electric Stimulation Therapy; Epilepsy, Generalized; Humans; Lamotrigine; Practice Guidelines as Topic; Syndrome; Triazines; Vagus Nerve; Valproic Acid | 2005 |
Treatment considerations for patients experiencing rapid-cycling bipolar disorder.
Topics: Antidepressive Agents; Antimanic Agents; Bipolar Disorder; Diagnosis, Differential; Drug Administration Schedule; Humans; Lamotrigine; Lithium Carbonate; Nursing Assessment; Patient Care Planning; Patient Selection; Periodicity; Practice Guidelines as Topic; Psychiatric Nursing; Psychiatric Status Rating Scales; Risk Factors; Severity of Illness Index; Time Factors; Treatment Failure; Triazines; Valproic Acid | 2006 |
Anticonvulsants in bipolar disorder.
Topics: Anticonvulsants; Bipolar Disorder; Carbamazepine; Humans; Lamotrigine; Triazines; Valproic Acid | 2006 |
[Epilepsy and male sexual dysfunction: etiology, diagnosis and therapy].
Topics: Androgens; Anticonvulsants; Bromocriptine; Carbamazepine; Cognition; Enzyme Induction; Epilepsy; Gonadal Steroid Hormones; Humans; Lamotrigine; Liver; Male; Oxcarbazepine; Phenytoin; Sexual Dysfunctions, Psychological; Testosterone; Triazines; Valproic Acid | 2006 |
Maintenance treatment of bipolar disorder: Applying research to clinical practice.
Topics: Anticonvulsants; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Bipolar Disorder; Carbamazepine; Evidence-Based Medicine; Humans; Lamotrigine; Lithium Carbonate; Olanzapine; Piperazines; Quinolones; Triazines; Valproic Acid | 2006 |
Differentiating bipolar disorder from depression in primary care.
Topics: Bipolar Disorder; Depression; Depressive Disorder, Major; Diagnosis, Differential; Humans; Lamotrigine; Lithium Compounds; Physicians, Family; Primary Health Care; Triazines; Valproic Acid | 2007 |
The role of mood stabilisers in the treatment of the depressive facet of bipolar disorders.
Topics: Affective Symptoms; Animals; Antimanic Agents; Bipolar Disorder; Carbamazepine; Depressive Disorder; Disease Models, Animal; Humans; Lamotrigine; Lithium Compounds; Rats; Triazines; Valproic Acid | 2007 |
Antiepileptic drugs and mood stability.
Topics: Affect; Anticonvulsants; Bipolar Disorder; Carbamazepine; Clinical Trials as Topic; Humans; Lamotrigine; Treatment Outcome; Triazines; Valproic Acid | 2007 |
[Anticonvulsants in the treatment of bipolar disorder].
Topics: Anticonvulsants; Antimanic Agents; Bipolar Disorder; Carbamazepine; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Lamotrigine; Phenytoin; Treatment Outcome; Triazines; Valproic Acid | 2007 |
A systematic review and economic model of the clinical effectiveness and cost-effectiveness of interventions for preventing relapse in people with bipolar disorder.
Topics: Adult; Antidepressive Agents; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Carbamazepine; Cognitive Behavioral Therapy; Cost-Benefit Analysis; Databases, Bibliographic; Female; Humans; Lamotrigine; Lithium; Male; Models, Economic; Olanzapine; Outcome and Process Assessment, Health Care; Randomized Controlled Trials as Topic; Secondary Prevention; Triazines; Valproic Acid | 2007 |
Anticonvulsants for the treatment of behavioral and psychological symptoms of dementia: a literature review.
Topics: Aggression; Amines; Anticonvulsants; Carbamazepine; Cognition Disorders; Cyclohexanecarboxylic Acids; Dementia; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Neuropsychological Tests; Psychomotor Disorders; Triazines; Valproic Acid | 2008 |
Juvenile myoclonic epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Child; Diagnosis, Differential; Electroencephalography; Humans; Lamotrigine; Myoclonic Epilepsy, Juvenile; Triazines; Valproic Acid | 2007 |
[Caffeine and antiepileptic drugs: experimental and clinical data].
Topics: Animals; Anticonvulsants; Caffeine; Carbamazepine; Dose-Response Relationship, Drug; Drug Interactions; Electroshock; Humans; Lamotrigine; Mice; Nipecotic Acids; Phenobarbital; Phenytoin; Seizures; Tiagabine; Triazines; Valproic Acid | 2007 |
Treatment of juvenile myoclonic epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Female; Humans; Infant; Lamotrigine; Levetiracetam; Male; Myoclonic Epilepsy, Juvenile; Piracetam; Sex Factors; Triazines; Valproic Acid | 2008 |
[Mood stabilizers--past, present and future].
Topics: Affect; Antimanic Agents; Bipolar Disorder; Calcium; Carbamazepine; Depressive Disorder; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Lamotrigine; Lithium Compounds; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Mood Disorders; Triazines; Valproic Acid | 2008 |
[Anticonvulsant mood stabilizers in the treatment of behavioral and psychological symptoms of dementia (BPSD)].
Topics: Aged; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Dementia; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Oxcarbazepine; Psychomotor Agitation; Topiramate; Treatment Outcome; Triazines; Valproic Acid | 2008 |
Epileptic disorders in pregnancy: an overview.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Epilepsy; Female; Folic Acid; Hemorrhage; Humans; Lamotrigine; Obstetrics; Pregnancy; Pregnancy Complications; Risk; Seizures; Triazines; Valproic Acid | 2008 |
[Empirical evidence for the use of anticonvulsants in personality disorders].
Topics: Amines; Anticonvulsants; Borderline Personality Disorder; Carbamazepine; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Oxcarbazepine; Personality Disorders; Pregabalin; Randomized Controlled Trials as Topic; Topiramate; Triazines; Valproic Acid | 2009 |
[Mood stabilizer in the psychopharmacotherapy of borderline personality disorder].
Topics: Anticonvulsants; Antimanic Agents; Borderline Personality Disorder; Carbamazepine; Female; Fructose; Humans; Lamotrigine; Lithium Compounds; Male; Randomized Controlled Trials as Topic; Topiramate; Triazines; Valproic Acid | 2009 |
Adding lithium or anticonvulsants to antipsychotics for the treatment of schizophrenia: useful strategy or exercise in futility?
Topics: Anticonvulsants; Antimanic Agents; Antipsychotic Agents; Delayed-Action Preparations; Drug Therapy, Combination; Humans; Lamotrigine; Lithium Carbonate; Medical Futility; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Schizophrenia; Schizophrenic Psychology; Treatment Failure; Triazines; Valproic Acid | 2009 |
Anticonvulsants in the treatment of major depressive disorder: an overview.
Topics: Anticonvulsants; Antidepressive Agents; Carbamazepine; Clinical Trials as Topic; Depressive Disorder, Major; Drug Therapy, Combination; Evidence-Based Medicine; Humans; Lamotrigine; Treatment Outcome; Triazines; Valproic Acid | 2009 |
Early intervention in bipolar disorder, part II: therapeutics.
Topics: Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Brain; Early Diagnosis; Humans; Lamotrigine; Lithium Compounds; Riluzole; Triazines; Valproic Acid | 2008 |
The first line of therapy in a girl with juvenile myoclonic epilepsy: should it be valproate or a new agent?
Topics: Anticonvulsants; Congenital Abnormalities; Delayed-Action Preparations; Drug Design; Epilepsy, Generalized; Female; Fructose; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Male; Myoclonic Epilepsy, Juvenile; Piracetam; Pregnancy; Risk Assessment; Topiramate; Treatment Outcome; Triazines; Valproic Acid; Weight Gain; Zonisamide | 2009 |
Rational polytherapy.
Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Drug Synergism; Drug Therapy, Combination; Epilepsy; Humans; Lamotrigine; Sodium Channel Blockers; Treatment Outcome; Triazines; Valproic Acid | 2009 |
Is the brain arachidonic acid cascade a common target of drugs used to manage bipolar disorder?
Topics: Animals; Anticonvulsants; Antidepressive Agents; Arachidonic Acid; Bipolar Disorder; Brain; Carbamazepine; Fructose; Humans; Lamotrigine; Lithium Compounds; Molecular Structure; Signal Transduction; Topiramate; Triazines; Valproic Acid | 2009 |
The teratogenic risk of antiepileptic drug polytherapy.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Australia; Drug Therapy, Combination; Female; Fetal Diseases; Fetus; Humans; Infant, Newborn; Lamotrigine; Logistic Models; Maternal-Fetal Exchange; Pregnancy; Pregnancy Complications; Registries; Risk; Risk Factors; Teratogens; Triazines; Valproic Acid | 2010 |
Frequency of and rationales for the combined use of electroconvulsive therapy and antiepileptic drugs in Austria and the literature.
Topics: Anticonvulsants; Austria; Bipolar Disorder; Carbamazepine; Combined Modality Therapy; Electroconvulsive Therapy; Guidelines as Topic; Humans; Lamotrigine; Lithium Carbonate; Oxcarbazepine; Treatment Outcome; Triazines; Valproic Acid | 2009 |
Is anticonvulsant treatment of mania a class effect? Data from randomized clinical trials.
Topics: Amines; Anticonvulsants; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Interactions; Drug Therapy, Combination; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Lithium Compounds; Oxcarbazepine; Randomized Controlled Trials as Topic; Topiramate; Triazines; Valproic Acid | 2011 |
[Sense and sensibility: bipolar affective disorder as a battlefield of cognitions and emotions--lamotrigine therapy as a peacekeeper].
Topics: Adolescent; Adult; Affect; Aged; Antimanic Agents; Bipolar Disorder; Cerebral Cortex; Child; Clinical Trials as Topic; Cognition; Cognition Disorders; Epigenesis, Genetic; Gyrus Cinguli; Humans; Lamotrigine; Limbic System; Lithium Compounds; Middle Aged; Schizophrenic Psychology; Stress, Psychological; Treatment Outcome; Triazines; Valproic Acid | 2010 |
Tolerance to the prophylactic effects of carbamazepine and related mood stabilizers in the treatment of bipolar disorders.
Topics: Amygdala; Animals; Anticonvulsants; Bipolar Disorder; Carbamazepine; Drug Resistance; Drug Tolerance; Humans; Kindling, Neurologic; Lamotrigine; Lithium Compounds; Mood Disorders; Seizures; Triazines; Valproic Acid | 2011 |
[Treatment of bipolar disorder during pregnancy and in the postpartum period].
Topics: Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Contraindications; Female; Humans; Lactation; Lamotrigine; Lithium Compounds; Pregnancy; Pregnancy Complications; Puerperal Disorders; Risk Factors; Triazines; Valproic Acid | 2011 |
[Rational combinations of antiepileptic drugs for refractory epilepsy].
Topics: Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carbamazepine; Clinical Trials as Topic; Disease Models, Animal; Drug Interactions; Drug Resistance; Drug Therapy, Combination; Epilepsy; Fructose; Humans; Lamotrigine; Levetiracetam; Multidrug Resistance-Associated Proteins; Piracetam; Prognosis; Topiramate; Triazines; Valproic Acid | 2011 |
[Pregabalin and gabapentin in multiple sclerosis: clinical experiences and therapeutic implications].
Topics: Adult; Aged; Aged, 80 and over; Amines; Anticonvulsants; Antineoplastic Agents; Carbamazepine; Cohort Studies; Cyclohexanecarboxylic Acids; Disability Evaluation; Drug Therapy, Combination; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Ion Channels; Lamotrigine; Male; Middle Aged; Mitoxantrone; Multiple Sclerosis; Neurologic Examination; Pregabalin; Retrospective Studies; Triazines; Valproic Acid; Young Adult | 2011 |
[The optimal combination of ECT with pharmacotherapy].
Topics: Affect; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Antimanic Agents; Carbamazepine; Electroconvulsive Therapy; Humans; Lamotrigine; Lithium Compounds; Mood Disorders; Schizophrenia; Selective Serotonin Reuptake Inhibitors; Tranquilizing Agents; Triazines; Valproic Acid | 2011 |
[Drug-induced tremor].
Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Antagonists; Animals; Anticonvulsants; Antidepressive Agents; Antipsychotic Agents; Bronchodilator Agents; Cimetidine; Histamine H2 Antagonists; Humans; Immunosuppressive Agents; Lamotrigine; Lithium Compounds; Pindolol; Theophylline; Tremor; Triazines; Valproic Acid | 2011 |
Takotsubo syndrome (TKS): a possible mechanism of sudden unexplained death in epilepsy (SUDEP).
Topics: Adrenergic beta-1 Receptor Antagonists; Anticonvulsants; Aspirin; Bisoprolol; Death, Sudden; Epilepsy; Female; Fibrinolytic Agents; Humans; Lamotrigine; Middle Aged; Perindopril; Takotsubo Cardiomyopathy; Triazines; Valproic Acid | 2012 |
Beneficial effects of mood stabilizers lithium, valproate and lamotrigine in experimental stroke models.
Topics: Animals; Antipsychotic Agents; Bipolar Disorder; Disease Models, Animal; Humans; Lamotrigine; Lithium Compounds; Stroke; Triazines; Valproic Acid | 2011 |
Lamotrigine XR conversion to monotherapy: first study using a historical control group.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Delivery Systems; Epilepsies, Partial; Female; Follow-Up Studies; Humans; International Cooperation; Lamotrigine; Male; Middle Aged; Treatment Outcome; Triazines; Valproic Acid; Young Adult | 2012 |
[Lithium and anticonvulsants in bipolar depression].
Topics: Anticonvulsants; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Clinical Trials as Topic; Drug Interactions; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Humans; Lamotrigine; Lithium Carbonate; Secondary Prevention; Treatment Outcome; Triazines; Valproic Acid | 2011 |
[Mood stabilizers].
Topics: Antimanic Agents; Bipolar Disorder; Carbamazepine; Humans; Lamotrigine; Lithium; Triazines; Valproic Acid | 2012 |
Mood stabilizers for the treatment of behavioral and psychological symptoms of dementia: an update review.
Topics: Antipsychotic Agents; Carbamazepine; Dementia; Humans; Lamotrigine; Oxcarbazepine; Triazines; Valproic Acid | 2012 |
[Juvenile myoclonic epilepsy].
Topics: Adolescent; Anticonvulsants; Diagnosis, Differential; Electroencephalography; Female; Humans; Lamotrigine; Levetiracetam; Male; Myoclonic Epilepsy, Juvenile; Myoclonus; Piracetam; Prognosis; Risk Factors; Treatment Outcome; Triazines; Valproic Acid | 2012 |
[Mood stabilizer].
Topics: Antimanic Agents; Bipolar Disorder; Carbamazepine; Humans; Lamotrigine; Lithium Compounds; Triazines; Valproic Acid | 2012 |
Seizures and intracranial hemorrhage.
Topics: Anticonvulsants; Carbamazepine; Congenital Abnormalities; Eclampsia; Epilepsy; Female; Folic Acid; Heparin; Humans; Infant, Newborn; Intracranial Hemorrhages; Lamotrigine; Monitoring, Physiologic; North America; Phenobarbital; Phenytoin; Pregnancy; Risk Factors; Seizures; Subarachnoid Hemorrhage; Triazines; Valproic Acid; Vitamin K | 2013 |
One-carbon metabolism and bipolar disorder.
Topics: Antidepressive Agents; Antimanic Agents; Bipolar Disorder; Brain; Folic Acid; Humans; Lamotrigine; Methylenetetrahydrofolate Reductase (NADPH2); Triazines; Valproic Acid | 2013 |
Pharmacotherapy for mood disorders in pregnancy: a review of pharmacokinetic changes and clinical recommendations for therapeutic drug monitoring.
Topics: Antidepressive Agents; Carbamazepine; Drug Monitoring; Female; Humans; Lamotrigine; Mood Disorders; Pregnancy; Pregnancy Complications; Triazines; Valproic Acid | 2014 |
Pharmacotherapy for tonic-clonic seizures.
Topics: Acetamides; Anticonvulsants; Epilepsy, Generalized; Epilepsy, Tonic-Clonic; Fructose; Humans; Lacosamide; Lamotrigine; Levetiracetam; Piracetam; Risk Factors; Seizures; Topiramate; Treatment Failure; Triazines; Valproic Acid | 2014 |
Developmental neurotoxicity and anticonvulsant drugs: a possible link.
Topics: Animals; Anticonvulsants; Breast Feeding; Carbamazepine; Cognition Disorders; Developmental Disabilities; Female; Humans; Lamotrigine; Phenobarbital; Phenytoin; Pregnancy; Prenatal Exposure Delayed Effects; Triazines; Valproic Acid | 2014 |
[Treatment of pediatric epilepsy].
Topics: Adolescent; Amines; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Dioxolanes; Drug Approval; Drug Substitution; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant; Lamotrigine; Levetiracetam; Patient Education as Topic; Piracetam; Practice Guidelines as Topic; Topiramate; Triazines; Triazoles; Valproic Acid | 2014 |
Anticonvulsants to treat post-traumatic stress disorder.
Topics: Anti-Anxiety Agents; Anticonvulsants; Fructose; Humans; Lamotrigine; Nipecotic Acids; Stress Disorders, Post-Traumatic; Tiagabine; Topiramate; Triazines; Valproic Acid | 2014 |
Comparative efficacy and acceptability of drug treatments for bipolar depression: a multiple-treatments meta-analysis.
Topics: Adult; Antidepressive Agents; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Bipolar Disorder; Depression; Dibenzothiazepines; Drug Therapy, Combination; Fluoxetine; Humans; Isoindoles; Lamotrigine; Lithium Compounds; Lurasidone Hydrochloride; Monoamine Oxidase Inhibitors; Olanzapine; Piperazines; Quetiapine Fumarate; Quinolones; Randomized Controlled Trials as Topic; Risperidone; Selective Serotonin Reuptake Inhibitors; Thiazoles; Treatment Outcome; Triazines; Valproic Acid | 2014 |
Lamotrigine-induced severe cutaneous adverse reaction: Update data from 1999-2014.
Topics: Adult; Aged; Anticonvulsants; Drug Therapy, Combination; Female; Humans; Lamotrigine; Male; Middle Aged; Stevens-Johnson Syndrome; Triazines; Valproic Acid | 2015 |
Management of adverse effects of mood stabilizers.
Topics: Anticonvulsants; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Carbamazepine; Disease Management; Humans; Lamotrigine; Lithium Compounds; Oxcarbazepine; Triazines; Valproic Acid | 2015 |
Alopecias due to drugs and other skin and systemic disorders.
Topics: Alopecia; Anticonvulsants; Antidepressive Agents; Antineoplastic Agents; Dermatologic Agents; Dermatomycoses; Diet; Folliculitis; Herpes Zoster; HIV Infections; Humans; Isotretinoin; Lamotrigine; Lithium Compounds; Lupus Erythematosus, Systemic; Malnutrition; Mycosis Fungoides; Paroxetine; Sarcoidosis; Seasons; Skin Neoplasms; Starvation; Stress, Psychological; Syphilis; Triazines; Valproic Acid | 2015 |
Bipolar Disorder in Pregnancy and Postpartum: Principles of Management.
Topics: Antipsychotic Agents; Bipolar Disorder; Electroconvulsive Therapy; Female; Humans; Lactation; Lamotrigine; Lithium Compounds; Postpartum Period; Pregnancy; Pregnancy Complications; Risk; Triazines; Valproic Acid | 2016 |
[Preconceptional and perinatal challenges of pregnancy in women with epilepsy].
Topics: Adult; Amines; Anticonvulsants; Benzodiazepines; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Levetiracetam; Oxcarbazepine; Parturition; Perinatal Care; Phenobarbital; Phenytoin; Piracetam; Preconception Care; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Teratogens; Triazines; Valproic Acid | 2016 |
Topics: AC133 Antigen; Acenaphthenes; Acer; Acrosome Reaction; Adult; Agaricales; Aged; Aged, 80 and over; Animals; Animals, Zoo; Anti-Bacterial Agents; Anticoagulants; Antifungal Agents; Antimanic Agents; Antioxidants; Aortic Valve; Area Under Curve; ATP Binding Cassette Transporter, Subfamily G, Member 2; Bacillus; Bacterial Toxins; Bacterial Typing Techniques; Base Composition; Beauveria; Binge Drinking; Biomarkers; Bipolar Disorder; Blood Coagulation; Blotting, Western; Brachytherapy; Calcium Channels, L-Type; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Cell Wall; Cells, Cultured; Ceramics; Chi-Square Distribution; China; Chlorophyll; Chlorophyta; Chloroplasts; Cholesterol, HDL; Chromatography, High Pressure Liquid; Chromobacterium; Clostridium perfringens; Clozapine; Constriction, Pathologic; Coronary Artery Bypass; Corticotropin-Releasing Hormone; Cross-Sectional Studies; Cytochrome P-450 CYP2C9; Dental Porcelain; Dental Restoration Failure; Dental Stress Analysis; Designer Drugs; Diaminopimelic Acid; DNA Fingerprinting; DNA, Bacterial; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Dosage Calculations; Drug Evaluation, Preclinical; Drug Resistance, Bacterial; Elasticity Imaging Techniques; Epsilonproteobacteria; Equipment Design; Ericaceae; Excitatory Amino Acid Antagonists; False Negative Reactions; Fatty Acids; Female; Food Analysis; Fresh Water; Gene Expression Regulation, Neoplastic; Glutathione; Graft Occlusion, Vascular; Heart Valve Prosthesis Implantation; Heart Ventricles; HEK293 Cells; Hemolymph; Humans; Hyaluronan Receptors; Hydrogen Peroxide; Hydrothermal Vents; Indoles; Inflammation Mediators; Inhibitory Concentration 50; Insecta; International Normalized Ratio; Isotope Labeling; Itraconazole; Kidney; Kinetics; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Lamotrigine; Lanthanoid Series Elements; Limit of Detection; Linear Models; Lipid Peroxidation; Liver; Liver Cirrhosis; Logistic Models; Lung Neoplasms; Lymph Node Excision; Lymphatic Metastasis; Male; Malondialdehyde; Mediastinum; Metronidazole; Mice; Mice, Nude; Mice, Transgenic; Microbial Sensitivity Tests; Microscopy, Fluorescence; Middle Aged; Monocytes; Monomeric GTP-Binding Proteins; Multivariate Analysis; Myocytes, Cardiac; Neoplasm Staging; Neoplastic Stem Cells; Neural Pathways; Nitrates; Nucleic Acid Hybridization; Octamer Transcription Factor-3; Odds Ratio; Oxidation-Reduction; Oxidative Stress; Peptidoglycan; Phantoms, Imaging; Pharmacogenetics; Pharmacogenomic Variants; Phenotype; Phospholipids; Photolysis; Photosynthesis; Phylogeny; Plant Extracts; Polychaeta; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Positron Emission Tomography Computed Tomography; Predictive Value of Tests; Preoperative Care; Prostatic Neoplasms; Pseudomonas aeruginosa; Pyrimidines; Pyrroles; Quorum Sensing; Radiology, Interventional; Radiopharmaceuticals; Radiotherapy Dosage; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Reference Values; Regression Analysis; Retrospective Studies; Reverse Transcriptase Polymerase Chain Reaction; Rhizosphere; Risk Factors; RNA, Ribosomal, 16S; ROC Curve; Rutin; Saphenous Vein; Seawater; Selenium; Semen Preservation; Sensitivity and Specificity; Septal Nuclei; Sequence Analysis, DNA; Serum Albumin; Serum Albumin, Human; Shear Strength; Sodium Pertechnetate Tc 99m; Sodium-Hydrogen Exchangers; Soil Microbiology; SOXB1 Transcription Factors; Spain; Species Specificity; Sperm Motility; Spermatozoa; Spheroids, Cellular; Spores, Fungal; Stroke; Superoxide Dismutase; Swine; Tandem Mass Spectrometry; Technetium Compounds; Technetium Tc 99m Exametazime; Technetium Tc 99m Sestamibi; Temperature; Thiosulfates; Thrombosis; Thyroid Neoplasms; Transducers; Transfection; Transplantation, Heterologous; Treatment Outcome; Triazines; Tumor Burden; Urocortins; Uterine Cervical Neoplasms; Vacuoles; Valproic Acid; Ventral Tegmental Area; Vitamin K 2; Vitamin K Epoxide Reductases; Warfarin; Water Microbiology; Young Adult | 2016 |
The effect of mood-stabilizing drugs on cytokine levels in bipolar disorder: A systematic review.
Topics: Affect; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Cytokines; Female; Humans; Lamotrigine; Lithium; Triazines; Valproic Acid | 2016 |
Antiepileptic dosing for critically ill adult patients receiving renal replacement therapy.
Topics: Acetamides; Acute Kidney Injury; Amines; Anticonvulsants; Carbamates; Critical Illness; Cyclohexanecarboxylic Acids; Dibenzazepines; Dose-Response Relationship, Drug; Ethosuximide; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lacosamide; Lamotrigine; Levetiracetam; Phenobarbital; Phenylcarbamates; Phenylenediamines; Phenytoin; Piracetam; Propylene Glycols; Renal Dialysis; Renal Replacement Therapy; Seizures; Topiramate; Triazines; Valproic Acid; Zonisamide | 2016 |
Ethosuximide, sodium valproate or lamotrigine for absence seizures in children and adolescents.
Topics: Adolescent; Anticonvulsants; Child; Epilepsy, Absence; Ethosuximide; Humans; Lamotrigine; Randomized Controlled Trials as Topic; Triazines; Valproic Acid | 2017 |
Pregnancy Outcomes Following In Utero Exposure to Lamotrigine: A Systematic Review and Meta-Analysis.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Infant, Newborn; Lamotrigine; Mood Disorders; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Triazines; Valproic Acid | 2017 |
Anticonvulsant drugs for generalized tonic-clonic epilepsy.
Topics: Acetamides; Anticonvulsants; Epilepsy, Generalized; Epilepsy, Tonic-Clonic; Female; Fructose; Humans; Isoxazoles; Lacosamide; Lamotrigine; Levetiracetam; Male; Nitriles; Piracetam; Pyridones; Randomized Controlled Trials as Topic; Topiramate; Treatment Outcome; Triazines; Valproic Acid; Zonisamide | 2017 |
Antiepileptic drug monotherapy for epilepsy: a network meta-analysis of individual participant data.
Topics: Adult; Amines; Anticonvulsants; Carbamazepine; Child; Cyclohexanecarboxylic Acids; Epilepsies, Partial; Epilepsy; Epilepsy, Generalized; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Network Meta-Analysis; Oxcarbazepine; Phenobarbital; Phenytoin; Piracetam; Remission Induction; Topiramate; Triazines; Valproic Acid; Zonisamide | 2017 |
Comparative safety of antiepileptic drugs for neurological development in children exposed during pregnancy and breast feeding: a systematic review and network meta-analysis.
Topics: Anticonvulsants; Autistic Disorder; Bayes Theorem; Breast Feeding; Carbamazepine; Child; Epilepsy; Female; Humans; Lamotrigine; Observational Studies as Topic; Oxcarbazepine; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Triazines; Valproic Acid | 2017 |
Lamotrigine versus valproic acid monotherapy for generalised epilepsy: A meta-analysis of comparative studies.
Topics: Anticonvulsants; Epilepsy, Generalized; Female; Humans; Lamotrigine; Male; Triazines; Valproic Acid | 2017 |
Essential Oils as an Alternative to Pyrethroids' Resistance against Anopheles Species Complex Giles (Diptera: Culicidae).
Topics: Animals; Anopheles; Caco-2 Cells; Carbamazepine; Diptera; Hep G2 Cells; Humans; Lamotrigine; Levetiracetam; Oils, Volatile; Phenytoin; Piracetam; Pyrethrins; Triazines; Valproic Acid | 2017 |
Antiepileptic drug monotherapy for epilepsy: a network meta-analysis of individual participant data.
Topics: Adult; Amines; Anticonvulsants; Carbamazepine; Child; Cyclohexanecarboxylic Acids; Epilepsies, Partial; Epilepsy; Epilepsy, Generalized; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Network Meta-Analysis; Oxcarbazepine; Phenobarbital; Phenytoin; Piracetam; Remission Induction; Topiramate; Triazines; Valproic Acid; Zonisamide | 2017 |
Comparative efficacy of antiepileptic drugs in children and adolescents: A network meta-analysis.
Topics: Adolescent; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Resistant Epilepsy; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Ethosuximide; Hormones; Humans; Infant; Lamotrigine; Levetiracetam; Network Meta-Analysis; Nitriles; Odds Ratio; Piracetam; Pyridones; Spasms, Infantile; Treatment Outcome; Triazines; Valproic Acid | 2018 |
Is there consensus across international evidence-based guidelines for the psychotropic drug management of bipolar disorder during the perinatal period?
Topics: Anticonvulsants; Antidepressive Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Breast Feeding; Carbamazepine; Consensus; Electroconvulsive Therapy; Evidence-Based Medicine; Female; Humans; Lamotrigine; Lithium; Practice Guidelines as Topic; Pregnancy; Psychotropic Drugs; Retrospective Studies; Triazines; Valproic Acid | 2018 |
A Practical Guide to Treatment of Childhood Absence Epilepsy.
Topics: Anticonvulsants; Child; Child, Preschool; Drug-Related Side Effects and Adverse Reactions; Electroencephalography; Epilepsy, Absence; Ethosuximide; Female; Humans; Lamotrigine; Male; Practice Guidelines as Topic; Seizures; Treatment Outcome; Valproic Acid | 2019 |
Ethosuximide, sodium valproate or lamotrigine for absence seizures in children and adolescents.
Topics: Adolescent; Anticonvulsants; Child; Epilepsy, Absence; Ethosuximide; Humans; Lamotrigine; Randomized Controlled Trials as Topic; Valproic Acid | 2019 |
Choice of therapeutic anti-seizure medication in patients with brain tumour.
Topics: Anticonvulsants; Brain Neoplasms; Drug Therapy, Combination; Epilepsy; Gabapentin; Glioma; Humans; Lamotrigine; Levetiracetam; Neoplasm Grading; Phenytoin; Survival Rate; Topiramate; Valproic Acid; Zonisamide | 2019 |
Pharmacotherapies for co-occurring substance use and bipolar disorders: A systematic review.
Topics: Anticonvulsants; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Comorbidity; Humans; Lamotrigine; Lithium Compounds; Quetiapine Fumarate; Substance-Related Disorders; Topiramate; Valproic Acid | 2019 |
Clinical opinion: Earlier employment of polytherapy in sequential pharmacotherapy of epilepsy.
Topics: Anticonvulsants; Drug Resistant Epilepsy; Drug Therapy, Combination; Epilepsy; Humans; Lamotrigine; Valproic Acid | 2019 |
Effects of Second-Generation Antiepileptic Drugs Compared to First-Generation Antiepileptic Drugs on Bone Metabolism in Patients with Epilepsy: A Meta-Analysis.
Topics: Anticonvulsants; Bone and Bones; Carbamazepine; Clinical Trials as Topic; Epilepsy; Humans; Lamotrigine; Levetiracetam; Prognosis; Valproic Acid | 2019 |
A reappraisal of atypical absence seizures in children and adults: therapeutic implications.
Topics: Anticonvulsants; Epilepsy, Generalized; Ethosuximide; Humans; Lamotrigine; Lennox Gastaut Syndrome; ras GTPase-Activating Proteins; Valproic Acid | 2019 |
Pharmacodynamic interactions of antiepileptic drugs: From bench to clinical practice.
Topics: Animals; Anticonvulsants; Drug Evaluation, Preclinical; Drug Interactions; Drug Therapy, Combination; Epilepsy; Humans; Lacosamide; Lamotrigine; Prospective Studies; Valproic Acid | 2020 |
[Transfer Mechanisms of Compounds between Mother and Fetus/Infant Aimed for Optimized Medication during Pregnancy and Breastfeeding].
Topics: Anticonvulsants; Benzodiazepines; Biological Transport; Breast Feeding; Cell Line; Epilepsy; Female; Folate Receptor 1; Gabapentin; Gene Expression; Humans; Lactation; Lamotrigine; Large Neutral Amino Acid-Transporter 1; Maternal-Fetal Exchange; Milk, Human; Placenta; Pregnancy; Pregnancy Complications; Proton-Coupled Folate Transporter; Valproic Acid | 2020 |
Bipolar disorders.
Topics: Adolescent; Adult; Anticonvulsants; Antidepressive Agents; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Carbamazepine; Cardiovascular Diseases; Child; Child Abuse; Comorbidity; Depressive Disorder, Major; Environmental Exposure; Humans; Lamotrigine; Lithium; Mania; Suicide; Suicide Prevention; Valproic Acid; Young Adult | 2020 |
Ethosuximide, sodium valproate or lamotrigine for absence seizures in children and adolescents.
Topics: Adolescent; Anticonvulsants; Child; Epilepsy, Absence; Ethosuximide; Female; Humans; Lamotrigine; Male; Randomized Controlled Trials as Topic; Seizures; Treatment Failure; Valproic Acid | 2021 |
Use of Phenytoin, Phenobarbital Carbamazepine, Levetiracetam Lamotrigine and Valproate in Pregnancy and Breastfeeding: Risk of Major Malformations, Dose-dependency, Monotherapy vs Polytherapy, Pharmacokinetics and Clinical Implications.
Topics: Anticonvulsants; Breast Feeding; Carbamazepine; Epilepsy; Female; Humans; Lamotrigine; Levetiracetam; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Valproic Acid | 2021 |
Initial Management of Seizure in Adults.
Topics: Adolescent; Adult; Anticonvulsants; Diagnosis, Differential; Electroencephalography; Epilepsy; Ethanol; Female; Humans; Lamotrigine; Levetiracetam; Practice Guidelines as Topic; Seizures; Valproic Acid | 2021 |
Genetics and antiepileptic mood stabilizer treatment response in bipolar disorder: what do we know?
Topics: Anticonvulsants; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Carbamazepine; Humans; Lamotrigine; Mood Disorders; Treatment Outcome; Valproic Acid | 2021 |
The efficacy of lamotrigine after failure of the first administration of valproate in treating epilepsy: a systematic review and meta-analysis.
Topics: Epilepsy; Humans; Lamotrigine; Quality of Life; Triazines; Valproic Acid | 2022 |
Evidence-based treatment strategies for rapid cycling bipolar disorder, a systematic review.
Topics: Anticonvulsants; Antipsychotic Agents; Aripiprazole; Bipolar Disorder; Humans; Lamotrigine; Olanzapine; Quetiapine Fumarate; Valproic Acid | 2022 |
Side effects of long-term oral anti-seizure drugs on thyroid hormones in patients with epilepsy: a systematic review and network meta-analysis.
Topics: Anticonvulsants; Carbamazepine; Epilepsy; Humans; Lamotrigine; Levetiracetam; Network Meta-Analysis; Oxcarbazepine; Phenobarbital; Phenytoin; Thyroid Hormones; Thyrotropin; Topiramate; Valproic Acid | 2022 |
The interplay of epilepsy with impaired mitophagy and autophagy linked dementia (MAD): A review of therapeutic approaches.
Topics: Anticonvulsants; Carbamazepine; Dementia; Epilepsy; Felbamate; Gabapentin; Humans; Inflammasomes; Lamotrigine; Mitophagy; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Oxcarbazepine; Parkinson Disease; Phenytoin; Seizures; Topiramate; Triazines; Ubiquitin-Protein Ligases; Valproic Acid | 2022 |
Breastfeeding while on treatment with antiseizure medications: a systematic review from the ILAE Women Task Force
Topics: Breast Feeding; Cannabidiol; Carbamazepine; Child; Clobazam; Clonazepam; Epilepsy; Ethosuximide; Everolimus; Felbamate; Female; Fenfluramine; Gabapentin; Humans; Infant; Lacosamide; Lamotrigine; Levetiracetam; Oxcarbazepine; Phenobarbital; Phenytoin; Prospective Studies; Tiagabine; Topiramate; Valproic Acid; Vigabatrin; Zonisamide | 2022 |
Psychobehavioural and Cognitive Adverse Events of Anti-Seizure Medications for the Treatment of Developmental and Epileptic Encephalopathies.
Topics: Autism Spectrum Disorder; Bromides; Cannabidiol; Clobazam; Cognition; Ethosuximide; Everolimus; Felbamate; Fenfluramine; Humans; Lacosamide; Lamotrigine; Levetiracetam; Pregabalin; Spasms, Infantile; Sulfides; Topiramate; Valproic Acid; Vigabatrin; Zinc Compounds; Zonisamide | 2022 |
[Medical Treatment of Epilepsy].
Topics: Anticonvulsants; Epilepsy; Female; Humans; Lamotrigine; Levetiracetam; Seizures; Valproic Acid | 2023 |
97 trial(s) available for valproic acid and lamotrigine
Article | Year |
---|---|
Lamotrigine for the treatment of epilepsy in childhood.
Topics: Adolescent; Anticonvulsants; Body Weight; Child; Child, Preschool; Consumer Product Safety; Dose-Response Relationship, Drug; Drug Therapy, Combination; Drug Tolerance; Epilepsy; Humans; Infant; Lamotrigine; Treatment Outcome; Triazines; Valproic Acid | 1995 |
Pharmacokinetic interactions between lamotrigine and other antiepileptic drugs in children with intractable epilepsy.
Topics: Administration, Oral; Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clonazepam; Drug Administration Schedule; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Epilepsy; Ethosuximide; Female; Humans; Lamotrigine; Male; Phenobarbital; Treatment Outcome; Triazines; Valproic Acid | 1996 |
Bidirectional interaction of valproate and lamotrigine in healthy subjects.
Topics: Analysis of Variance; Anticonvulsants; Drug Administration Schedule; Drug Interactions; Half-Life; Humans; Lamotrigine; Male; Reference Values; Time Factors; Triazines; Valproic Acid | 1996 |
Serum concentrations of lamotrigine in epileptic patients: the influence of dose and comedication.
Topics: Adult; Age Factors; Anticonvulsants; Body Weight; Carbamazepine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Lamotrigine; Male; Middle Aged; Phenobarbital; Phenytoin; Sex Factors; Triazines; Valproic Acid | 1996 |
Controlled trial of lamotrigine (Lamictal) for treatment-resistant partial seizures.
Topics: Adolescent; Adult; Anticonvulsants; Cross-Over Studies; Double-Blind Method; Epilepsy, Complex Partial; Humans; Lamotrigine; Middle Aged; Placebos; Triazines; Valproic Acid | 1996 |
Lamotrigine substitution study: evidence for synergism with sodium valproate? 105 Study Group.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Dose-Response Relationship, Drug; Drug Synergism; Epilepsy; Female; Humans; Lamotrigine; Male; Middle Aged; Retreatment; Treatment Outcome; Triazines; Valproic Acid | 1997 |
Prospective, open-label, add-on study of lamotrigine in 56 children with intractable generalized epilepsy.
Topics: Adolescent; Anticonvulsants; Benzodiazepines; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy, Generalized; Female; Humans; Infant; Lamotrigine; Male; Prospective Studies; Retreatment; Treatment Outcome; Triazines; Valproic Acid | 1997 |
Lamotrigine as add-on drug in children and adolescents with refractory epilepsy and mental delay: an open trial.
Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Developmental Disabilities; Drug Resistance; Drug Therapy, Combination; Electroencephalography; Epilepsy; Female; Humans; Lamotrigine; Male; Triazines; Valproic Acid | 1997 |
Lamotrigine in rapid-cycling bipolar disorder.
Topics: Adult; Anticonvulsants; Bipolar Disorder; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluoxetine; Humans; Lamotrigine; Lithium; Male; Middle Aged; Prospective Studies; Psychiatric Status Rating Scales; Regression Analysis; Treatment Outcome; Triazines; Valproic Acid | 1997 |
An active-control trial of lamotrigine monotherapy for partial seizures.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Double-Blind Method; Epilepsies, Partial; Exanthema; Female; Humans; Hydrogen Peroxide; Lamotrigine; Male; Middle Aged; Phenytoin; Triazines; Valproic Acid | 1998 |
Anticonvulsant therapy and suicide risk in affective disorders.
Topics: Amitriptyline; Anticonvulsants; Bipolar Disorder; Carbamazepine; Double-Blind Method; Female; Follow-Up Studies; Humans; Lamotrigine; Lithium; Male; Mood Disorders; Prospective Studies; Risk Factors; Suicide; Suicide Prevention; Triazines; Valproic Acid | 1999 |
Adding lamotrigine to valproate: incidence of rash and other adverse effects. Postmarketing Antiepileptic Drug Survey (PADS) Group.
Topics: Adolescent; Adult; Child; Dizziness; Drug Eruptions; Drug Hypersensitivity; Drug Therapy, Combination; Female; Follow-Up Studies; Gastrointestinal Diseases; Hallucinations; Headache; Humans; Incidence; Lamotrigine; Male; Middle Aged; Product Surveillance, Postmarketing; Prospective Studies; Sleep Initiation and Maintenance Disorders; Triazines; Valproic Acid | 1999 |
Effect of felbamate on clobazam and its metabolite kinetics in patients with epilepsy.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Carbamazepine; Child; Child, Preschool; Clobazam; Cytochrome P-450 Enzyme System; Drug Therapy, Combination; Epilepsies, Partial; Felbamate; Female; Humans; Lamotrigine; Male; Phenobarbital; Phenylcarbamates; Phenytoin; Propylene Glycols; Prospective Studies; Triazines; Valproic Acid | 1999 |
Plasma and urinary serotonin and 5-HIAA in children treated with lamotrigine for intractable epilepsy.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Female; Humans; Hydroxyindoleacetic Acid; Lamotrigine; Male; Serotonin; Triazines; Valproic Acid | 1999 |
Adding valproate to lamotrigine: a study of their pharmacokinetic interaction.
Topics: Adolescent; Adult; Aged; Child; Dose-Response Relationship, Drug; Drug Costs; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Lamotrigine; Male; Metabolic Clearance Rate; Middle Aged; Treatment Outcome; Triazines; Valproic Acid | 2000 |
Lack of an effect of valproate concentration on lamotrigine pharmacokinetics in developmentally disabled patients with epilepsy.
Topics: Adolescent; Adult; Algorithms; Anticonvulsants; Child; Chromatography, Gas; Chromatography, High Pressure Liquid; Developmental Disabilities; Drug Interactions; Epilepsy; Female; Humans; Lamotrigine; Male; Middle Aged; Models, Biological; Population; Triazines; Valproic Acid | 2000 |
Open study evaluating lamotrigine efficacy and safety in add-on treatment and consecutive monotherapy in patients with carbamazepine- or valproate-resistant epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Calcium Channel Blockers; Carbamazepine; Child; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Drug Tolerance; Epilepsy; Female; Humans; Lamotrigine; Male; Treatment Outcome; Triazines; Valproic Acid | 2000 |
Epilepsy and antiepileptic drug therapy in juvenile neuronal ceroid lipofuscinosis.
Topics: Adolescent; Adult; Age of Onset; Anticonvulsants; Child; Child, Preschool; Clonazepam; Comorbidity; Drug Administration Schedule; Drug Therapy, Combination; Epilepsy; Female; Finland; Follow-Up Studies; Humans; Lamotrigine; Male; Neuronal Ceroid-Lipofuscinoses; Phenobarbital; Treatment Outcome; Triazines; Valproic Acid | 2000 |
Clinical study of lamotrigine and valproic acid in patients with epilepsy: using a drug interaction to advantage?
Topics: Adult; Anticonvulsants; Area Under Curve; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Enzyme Inhibitors; Epilepsy; Female; Half-Life; Humans; Lamotrigine; Male; Middle Aged; Triazines; Valproic Acid | 2000 |
Developmental and therapeutic pharmacology of antiepileptic drugs.
Topics: Adolescent; Adult; Age Factors; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Administration Schedule; Drug Industry; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Epilepsies, Partial; Epilepsy; Half-Life; Humans; Infant; Intestinal Absorption; Isoxazoles; Lamotrigine; Prospective Studies; Treatment Outcome; Triazines; Valproic Acid; Zonisamide | 2000 |
Weight change associated with valproate and lamotrigine monotherapy in patients with epilepsy.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Body Weight; Child; Epilepsy; Female; Humans; Lamotrigine; Male; Middle Aged; Triazines; Valproic Acid | 2001 |
[Gabitril as an additive drug in therapy of intractable epileptic seizures in children].
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clonazepam; Drug Therapy, Combination; Epilepsies, Partial; Epilepsy, Generalized; Felbamate; Female; Follow-Up Studies; Humans; Lamotrigine; Male; Nipecotic Acids; Nitrazepam; Oxcarbazepine; Phenylcarbamates; Phenytoin; Propylene Glycols; Tiagabine; Triazines; Valproic Acid; Vigabatrin | 2000 |
Effect of divalproex-lamotrigine combination therapy in frontal lobe seizures.
Topics: Adolescent; Adult; Anticonvulsants; Drug Therapy, Combination; Epilepsy, Frontal Lobe; Female; Humans; Lamotrigine; Male; Middle Aged; Triazines; Valproic Acid | 2001 |
Urinary excretion of valproate metabolites in children and adolescents.
Topics: Adolescent; Aging; Anticonvulsants; Biotransformation; Child; Child, Preschool; Chromatography, Gas; Cross-Sectional Studies; Drug Combinations; Drug Interactions; Female; Humans; Hydrolysis; Lamotrigine; Male; Triazines; Valproic Acid | 2000 |
Randomized double-blind parallel-group study comparing cognitive effects of a low-dose lamotrigine with valproate and placebo in healthy volunteers.
Topics: Adult; Affect; Anticonvulsants; Cognition; Double-Blind Method; Epilepsy; Humans; Lamotrigine; Male; Neuropsychological Tests; Placebos; Psychomotor Performance; Triazines; Valproic Acid | 2002 |
The evolving role of topiramate among other mood stabilizers in the management of bipolar disorder.
Topics: Acetates; Acute Disease; Amines; Anticonvulsants; Antimanic Agents; Bipolar Disorder; Carbamazepine; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Lithium; Randomized Controlled Trials as Topic; Topiramate; Triazines; Valproic Acid | 2001 |
Topiramate therapeutic monitoring in patients with epilepsy: effect of concomitant antiepileptic drugs.
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Epilepsy; Female; Fructose; Humans; Lamotrigine; Male; Phenobarbital; Phenytoin; Prospective Studies; Topiramate; Triazines; Valproic Acid | 2002 |
Lamotrigine versus valproate monotherapy-associated weight change in adolescents with epilepsy: results from a post hoc analysis of a randomized, double-blind clinical trial.
Topics: Administration, Oral; Adolescent; Adult; Anticonvulsants; Body Mass Index; Child; Double-Blind Method; Epilepsy; Female; Humans; Lamotrigine; Male; Obesity; Risk Factors; Triazines; Valproic Acid; Weight Gain | 2003 |
Lamotrigine in adolescent mood disorders.
Topics: Adolescent; Anticonvulsants; Bipolar Disorder; Child; Delayed-Action Preparations; Drug Therapy, Combination; Humans; Lamotrigine; Retrospective Studies; Triazines; Valproic Acid | 2003 |
Lamotrigine monotherapy compared with carbamazepine, phenytoin, or valproate monotherapy in patients with epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug Evaluation; Drug Interactions; Drug Therapy, Combination; Drug Tolerance; Epilepsy; Female; Humans; Lamotrigine; Male; Middle Aged; Quality of Life; Seizures; Self-Assessment; Treatment Outcome; Triazines; Valproic Acid | 2003 |
Evaluation of VPA dose and concentration effects on lamotrigine pharmacokinetics: implications for conversion to lamotrigine monotherapy.
Topics: Adult; Confidence Intervals; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Female; Humans; Lamotrigine; Male; Middle Aged; Triazines; Valproic Acid | 2003 |
Factors associated with poor control in partial complex epilepsy.
Topics: Age of Onset; Anticonvulsants; Carbamazepine; Child; Drug Therapy, Combination; Electroencephalography; Epilepsy, Complex Partial; Female; Follow-Up Studies; Humans; Lamotrigine; Male; Phenobarbital; Predictive Value of Tests; Prospective Studies; Recurrence; Risk Factors; Treatment Outcome; Triazines; Valproic Acid | 2004 |
Lamotrigine for patients with juvenile myoclonic epilepsy following prior treatment with valproate: results of an open-label study.
Topics: Adolescent; Anticonvulsants; Child; Drug Evaluation; Humans; Lamotrigine; Myoclonic Epilepsy, Juvenile; Treatment Outcome; Triazines; Valproic Acid | 2004 |
Efficacy and tolerability of conversion to monotherapy with lamotrigine compared with valproate and carbamazepine in patients with epilepsy.
Topics: Adult; Anticonvulsants; Carbamazepine; Chi-Square Distribution; Drug Interactions; Drug Tolerance; Epilepsy; Female; Humans; Lamotrigine; Male; Middle Aged; Treatment Outcome; Triazines; Valproic Acid | 2004 |
Lamotrigine versus valproic acid as first-line monotherapy in newly diagnosed typical absence seizures: an open-label, randomized, parallel-group study.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Disease-Free Survival; Drug Administration Schedule; Electroencephalography; Epilepsy, Absence; Female; Follow-Up Studies; Humans; Lamotrigine; Male; Monitoring, Ambulatory; Treatment Outcome; Triazines; Valproic Acid | 2004 |
A dosing algorithm for converting from valproate monotherapy to lamotrigine monotherapy in patients with epilepsy.
Topics: Adolescent; Adult; Aged; Algorithms; Anticonvulsants; Confidence Intervals; Demography; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Evaluation; Drug Interactions; Drug Therapy, Combination; Drug Tolerance; Epilepsy; Female; Humans; Lamotrigine; Male; Middle Aged; Treatment Outcome; Triazines; Valproic Acid | 2005 |
Pharmacological outcomes in newly diagnosed epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsy; Female; Follow-Up Studies; Humans; Lamotrigine; Male; Retrospective Studies; Substance Withdrawal Syndrome; Time Factors; Treatment Outcome; Triazines; Valproic Acid | 2005 |
Effectiveness of lamotrigine in clinical practice: results of a retrospective population-based study.
Topics: Adult; Anticonvulsants; Drug Interactions; Epilepsy; Female; Humans; Lamotrigine; Logistic Models; Male; Middle Aged; Retrospective Studies; Time Factors; Treatment Outcome; Triazines; Valproic Acid | 2005 |
Analysis of pregabalin at therapeutic concentrations in human plasma/serum by reversed-phase HPLC.
Topics: Anticonvulsants; Calibration; Carbamazepine; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Interactions; Drug Stability; Drug Therapy, Combination; Epilepsy; gamma-Aminobutyric Acid; Humans; Lamotrigine; Pregabalin; Reproducibility of Results; Spectrophotometry, Ultraviolet; Triazines; Trinitrobenzenesulfonic Acid; Valproic Acid | 2005 |
The LAM-SAFE Study: lamotrigine versus carbamazepine or valproic acid in newly diagnosed focal and generalised epilepsies in adolescents and adults.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Demography; Epilepsies, Partial; Epilepsy, Generalized; Female; Humans; Lamotrigine; Male; Middle Aged; Time Factors; Treatment Outcome; Triazines; Valproic Acid | 2005 |
Plasma free carnitine in epilepsy children, adolescents and young adults treated with old and new antiepileptic drugs with or without ketogenic diet.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Carnitine; Child; Child, Preschool; Dietary Fats; Drug Therapy, Combination; Epilepsy; Female; Fructose; Humans; Infant; Ketosis; Lamotrigine; Male; Prospective Studies; Risk Factors; Topiramate; Triazines; Valproic Acid | 2006 |
Cognitive functioning in bipolar patients receiving lamotrigine: preliminary results.
Topics: Adult; Anticonvulsants; Bipolar Disorder; Carbamazepine; Cognition; Female; Humans; Lamotrigine; Male; Memory, Short-Term; Middle Aged; Neuropsychological Tests; Psychiatric Status Rating Scales; Treatment Outcome; Triazines; Valproic Acid; Verbal Behavior | 2006 |
Add-on lamotrigine treatment and plasma glutamate levels in epilepsy: relation to treatment response.
Topics: Adult; Anticonvulsants; Drug Therapy, Combination; Epilepsy; Female; Glutamic Acid; Humans; Lamotrigine; Male; Time Factors; Triazines; Valproic Acid | 2006 |
Quantitative EEG effects of carbamazepine, oxcarbazepine, valproate, lamotrigine, and possible clinical relevance of the findings.
Topics: Adolescent; Adult; Alpha Rhythm; Anticonvulsants; Carbamazepine; Child; Electroencephalography; Epilepsy; Female; Humans; Lamotrigine; Male; Occipital Lobe; Triazines; Valproic Acid | 2006 |
In utero antiepileptic drug exposure: fetal death and malformations.
Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Carbamazepine; Cognition; Female; Fetal Death; Humans; Lamotrigine; Phenytoin; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Prospective Studies; Triazines; Uterus; Valproic Acid | 2006 |
Valproate effects on kinetics of lamotrigine in pregnancy and treatment with oral contraceptives.
Topics: Anticonvulsants; Contraceptives, Oral; Drug Combinations; Epilepsy; Female; Humans; Kinetics; Lamotrigine; Metabolic Clearance Rate; Pregnancy; Pregnancy Complications; Triazines; Valproic Acid | 2006 |
Evaluation of renal tubular function in children taking anti-epileptic treatment.
Topics: Acetylglucosaminidase; Anticonvulsants; Biomarkers; Blood Urea Nitrogen; Carbamazepine; Child; Child, Preschool; Creatinine; Drug Therapy, Combination; Epilepsies, Partial; Epilepsy, Generalized; Humans; Kidney Tubules; Lamotrigine; Triazines; Valproic Acid | 2006 |
Lack of efficacy and potential aggravation of myoclonus with lamotrigine in Unverricht-Lundborg disease.
Topics: Acute Disease; Adult; Age of Onset; Anticonvulsants; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Lamotrigine; Male; Middle Aged; Myoclonus; Retrospective Studies; Treatment Outcome; Triazines; Unverricht-Lundborg Syndrome; Valproic Acid | 2006 |
The SANAD study of effectiveness of valproate, lamotrigine, or topiramate for generalised and unclassifiable epilepsy: an unblinded randomised controlled trial.
Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Cost-Benefit Analysis; Epilepsy, Generalized; Female; Follow-Up Studies; Fructose; Humans; Lamotrigine; Male; Quality-Adjusted Life Years; Time Factors; Topiramate; Treatment Failure; Triazines; Valproic Acid | 2007 |
Motor cortex excitability after vagus nerve stimulation in major depression.
Topics: Adult; Benzodiazepines; Citalopram; Clomipramine; Clozapine; Depressive Disorder; Doxepin; Drug Therapy, Combination; Electric Stimulation; Female; Humans; Lamotrigine; Lithium Carbonate; Male; Mianserin; Middle Aged; Mirtazapine; Morpholines; Motor Cortex; Neural Conduction; Neural Inhibition; Olanzapine; Paroxetine; Psychiatric Status Rating Scales; Reboxetine; Tranylcypromine; Triazines; Vagus Nerve; Valproic Acid | 2007 |
Sodium valproate versus lamotrigine: a randomised comparison of efficacy, tolerability and effects on circulating androgenic hormones in newly diagnosed epilepsy.
Topics: Adolescent; Adult; Aged; Androgens; Androstenedione; Anticonvulsants; Body Mass Index; Body Weight; Data Interpretation, Statistical; Epilepsy; Female; Humans; Lamotrigine; Male; Middle Aged; Sex Hormone-Binding Globulin; Testosterone; Triazines; Valproic Acid | 2007 |
Treatment adherence in individuals with rapid cycling bipolar disorder: results from a clinical-trial setting.
Topics: Adult; Antimanic Agents; Bipolar Disorder; Double-Blind Method; Female; Humans; Lamotrigine; Lithium Compounds; Male; Patient Compliance; Psychiatric Status Rating Scales; Triazines; Valproic Acid | 2007 |
Lack of pharmacokinetic interaction of levetiracetam on carbamazepine, valproic acid, topiramate, and lamotrigine in children with epilepsy.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Fructose; Humans; Lamotrigine; Levetiracetam; Male; Outcome Assessment, Health Care; Piracetam; Placebos; Topiramate; Triazines; Valproic Acid | 2007 |
Effect of open-label lamotrigine as monotherapy and adjunctive therapy on the self-assessed cognitive function scores of patients with bipolar I disorder.
Topics: Adult; Aged; Antidepressive Agents; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Cognition; Female; Humans; Lamotrigine; Male; Middle Aged; Neuropsychological Tests; Psychiatric Status Rating Scales; Triazines; Valproic Acid | 2007 |
A randomised controlled trial examining the longer-term outcomes of standard versus new antiepileptic drugs. The SANAD trial.
Topics: Adult; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsy; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Health Status Indicators; Humans; Lamotrigine; Male; Oxcarbazepine; Topiramate; Treatment Outcome; Triazines; Valproic Acid | 2007 |
Lamotrigine extended-release as adjunctive therapy for partial seizures.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Benzodiazepines; Carbamazepine; Delayed-Action Preparations; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Epilepsies, Partial; Female; Humans; Lamotrigine; Male; Middle Aged; Placebos; Time Factors; Treatment Outcome; Triazines; Valproic Acid | 2007 |
Adjunctive lamotrigine for partial seizures in patients aged 1 to 24 months.
Topics: Anticonvulsants; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Evaluation; Electroencephalography; Epilepsies, Partial; Female; Humans; Infant; Lamotrigine; Male; Treatment Outcome; Triazines; Valproic Acid | 2008 |
Aripiprazole therapy in 20 older adults with bipolar disorder: a 12-week, open-label trial.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Aripiprazole; Basal Ganglia Diseases; Bipolar Disorder; Depressive Disorder; Drug Synergism; Drug Therapy, Combination; Electrocardiography; Female; Humans; Interview, Psychological; Lamotrigine; Lithium Carbonate; Male; Middle Aged; Pilot Projects; Piperazines; Prospective Studies; Quinolones; Triazines; Valproic Acid | 2008 |
Hyperandrogenism, ovulatory dysfunction, and polycystic ovary syndrome with valproate versus lamotrigine.
Topics: Adolescent; Adult; Anovulation; Epilepsy; Female; Humans; Hyperandrogenism; Internationality; Lamotrigine; Ovulation; Polycystic Ovary Syndrome; Prospective Studies; Triazines; Valproic Acid | 2008 |
Lamotrigine and valproic acid have different effects on motorcortical neuronal excitability.
Topics: Adolescent; Adult; Analysis of Variance; Central Nervous System Agents; Electromyography; Evoked Potentials, Motor; Humans; Lamotrigine; Linear Models; Male; Motor Activity; Motor Cortex; Transcranial Magnetic Stimulation; Triazines; Valproic Acid; Young Adult | 2009 |
Effects of valproate or lamotrigine monotherapy on the reproductive endocrine and insulin-related metabolic profile in Chinese adults with epilepsy: a prospective randomized study.
Topics: Adolescent; Adult; Anticonvulsants; China; Cross-Sectional Studies; Dose-Response Relationship, Drug; Endocrine System; Epilepsy; Female; Follicle Stimulating Hormone; Hormones; Humans; Insulin; Lamotrigine; Luteinizing Hormone; Male; Metabolome; Middle Aged; Prospective Studies; Testosterone; Time Factors; Triazines; Valproic Acid; Young Adult | 2009 |
A double-blind randomized trial of mood stabilizer augmentation using lamotrigine and valproate for patients with schizophrenia who are stabilized and partially responsive.
Topics: Adult; Antimanic Agents; Antipsychotic Agents; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Lamotrigine; Male; Prospective Studies; Psychiatric Status Rating Scales; Quality of Life; Schizophrenia; Schizophrenic Psychology; Severity of Illness Index; Treatment Outcome; Triazines; Valproic Acid | 2009 |
[Valproic acid versus lamotrigine as a monotherapy for absence epilepsy in children].
Topics: Anticonvulsants; Child; Child, Preschool; Electroencephalography; Epilepsy, Absence; Female; Humans; Lamotrigine; Male; Triazines; Valproic Acid | 2009 |
Interleaved transcranial magnetic stimulation and fMRI suggests that lamotrigine and valproic acid have different effects on corticolimbic activity.
Topics: Adolescent; Adult; Anticonvulsants; Brain Mapping; Cerebral Cortex; Humans; Lamotrigine; Limbic System; Magnetic Resonance Imaging; Male; Transcranial Magnetic Stimulation; Triazines; Valproic Acid | 2010 |
Ethosuximide, valproic acid, and lamotrigine in childhood absence epilepsy.
Topics: Adolescent; Analysis of Variance; Anticonvulsants; Attention Deficit and Disruptive Behavior Disorders; Child; Child, Preschool; Double-Blind Method; Epilepsy, Absence; Ethosuximide; Female; Humans; Intention to Treat Analysis; Kaplan-Meier Estimate; Lamotrigine; Male; Seizures; Treatment Outcome; Triazines; Valproic Acid | 2010 |
Lamotrigine adjunctive therapy to lithium and divalproex in depressed patients with rapid cycling bipolar disorder and a recent substance use disorder: a 12-week, double-blind, placebo-controlled pilot study.
Topics: Adult; Analysis of Variance; Antimanic Agents; Bipolar Disorder; Chi-Square Distribution; Depression; Double-Blind Method; Drug Therapy, Combination; Humans; Lamotrigine; Lithium Compounds; Middle Aged; Ohio; Pilot Projects; Placebos; Psychiatric Status Rating Scales; Remission Induction; Substance-Related Disorders; Time Factors; Treatment Outcome; Triazines; Valproic Acid | 2010 |
Effects of carbamazepine and metabolites on IL-2, IL-5, IL-6, IL-10 and IFN-γ secretion in epileptic patients: the influence of co-medication.
Topics: Acridines; Adult; Aged; Anticonvulsants; Carbamazepine; Dibenzazepines; Drug Therapy, Combination; Epilepsy; Female; Humans; Interferon-gamma; Interleukins; Lamotrigine; Male; Middle Aged; Th1 Cells; Th2 Cells; Triazines; Valproic Acid; Young Adult | 2011 |
Efficacy and safety of adjunctive oral ziprasidone for acute treatment of depression in patients with bipolar I disorder: a randomized, double-blind, placebo-controlled trial.
Topics: Acute Disease; Adolescent; Adult; Aged; Antimanic Agents; Bipolar Disorder; Depressive Disorder, Major; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Lamotrigine; Lithium; Male; Middle Aged; Piperazines; Serotonin Antagonists; Thiazoles; Treatment Outcome; Triazines; Valproic Acid; Young Adult | 2011 |
Long-term control of epileptic drop attacks with the combination of valproate, lamotrigine, and a benzodiazepine: a 'proof of concept,' open label study.
Topics: Adolescent; Adult; Anticonvulsants; Benzodiazepines; Child; Child, Preschool; Drug Therapy, Combination; Electroencephalography; Epilepsy; Female; Humans; Lamotrigine; Male; Middle Aged; Syncope; Triazines; Valproic Acid; Young Adult | 2011 |
Using interleaved transcranial magnetic stimulation/functional magnetic resonance imaging (fMRI) and dynamic causal modeling to understand the discrete circuit specific changes of medications: lamotrigine and valproic acid changes in motor or prefrontal e
Topics: Adolescent; Adult; Anticonvulsants; Brain Mapping; Cerebral Cortex; Cross-Sectional Studies; Double-Blind Method; Functional Laterality; Humans; Lamotrigine; Magnetic Resonance Imaging; Male; Models, Neurological; Neural Pathways; Transcranial Magnetic Stimulation; Triazines; Valproic Acid; Young Adult | 2011 |
Lamotrigine XR conversion to monotherapy: first study using a historical control group.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Delivery Systems; Epilepsies, Partial; Female; Follow-Up Studies; Humans; International Cooperation; Lamotrigine; Male; Middle Aged; Treatment Outcome; Triazines; Valproic Acid; Young Adult | 2012 |
Pharmacokinetic drug interactions between clobazam and drugs metabolized by cytochrome P450 isoenzymes.
Topics: Adolescent; Adult; Anticonvulsants; Area Under Curve; Benzodiazepines; Caffeine; Central Nervous System Stimulants; Clinical Trials, Phase I as Topic; Clobazam; Cytochrome P-450 Enzyme System; Dextromethorphan; Drug Interactions; Female; Humans; Hypnotics and Sedatives; Hypoglycemic Agents; Isoenzymes; Lamotrigine; Male; Midazolam; Middle Aged; Models, Statistical; Pharmacokinetics; Prospective Studies; Tolbutamide; Triazines; Valproic Acid; Young Adult | 2012 |
Impact of age, weight and concomitant treatment on lamotrigine pharmacokinetics.
Topics: Adolescent; Adult; Age Factors; Anticonvulsants; Area Under Curve; Body Weight; Carbamazepine; Child; Dose-Response Relationship, Drug; Drug Interactions; Epilepsy; Female; Humans; Lamotrigine; Male; Models, Biological; Regression Analysis; Sex Factors; Triazines; Valproic Acid; Young Adult | 2012 |
Lamotrigine vs. lamotrigine plus divalproex in randomized, placebo-controlled maintenance treatment for bipolar depression.
Topics: Adult; Antimanic Agents; Bipolar Disorder; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Kaplan-Meier Estimate; Lamotrigine; Male; Middle Aged; Treatment Outcome; Triazines; Valproic Acid | 2012 |
[Efficacy and safety of the combined therapy of valproic acid and lamotrigine for epileptics].
Topics: Child; Child, Preschool; Drug Therapy, Combination; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epilepsy, Generalized; Female; Follow-Up Studies; Humans; Infant; Lamotrigine; Male; Prospective Studies; Seizures; Treatment Outcome; Triazines; Valproic Acid | 2012 |
Lamotrigine as add-on treatment to lithium and divalproex: lessons learned from a double-blind, placebo-controlled trial in rapid-cycling bipolar disorder.
Topics: Adolescent; Adult; Aged; Antimanic Agents; Bipolar Disorder; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Lamotrigine; Lithium Chloride; Male; Middle Aged; Psychiatric Status Rating Scales; Retrospective Studies; Triazines; Valproic Acid; Young Adult | 2012 |
Ethosuximide, valproic acid, and lamotrigine in childhood absence epilepsy: initial monotherapy outcomes at 12 months.
Topics: Age Factors; Anticonvulsants; Child; Child, Preschool; Dose-Response Relationship, Drug; Double-Blind Method; Epilepsy, Absence; Ethosuximide; Female; Humans; Lamotrigine; Male; Treatment Outcome; Triazines; Valproic Acid | 2013 |
Relative effectiveness of adjunctive risperidone on manic and depressive symptoms in mixed mania.
Topics: Adult; Antidepressive Agents; Antimanic Agents; Bipolar Disorder; Depressive Disorder; Diagnostic and Statistical Manual of Mental Disorders; Drug Resistance; Drug Therapy, Combination; Female; Humans; Lamotrigine; Lithium Compounds; Lost to Follow-Up; Male; Middle Aged; Psychiatric Status Rating Scales; Risperidone; Secondary Prevention; Time Factors; Triazines; Valproic Acid | 2013 |
Investigation into the long-term metabolic effects of aripiprazole adjunctive to lithium, valproate, or lamotrigine.
Topics: Adult; Antipsychotic Agents; Aripiprazole; Bipolar Disorder; Body Weight; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Lamotrigine; Lithium; Male; Metabolic Syndrome; Middle Aged; Obesity; Overweight; Piperazines; Quinolones; Time Factors; Treatment Outcome; Triazines; Valproic Acid | 2013 |
Efficacy and tolerability of lamotrigine in juvenile myoclonic epilepsy in adults: a prospective, unblinded randomized controlled trial.
Topics: Adolescent; Adult; Anticonvulsants; Female; Humans; Lamotrigine; Male; Middle Aged; Myoclonic Epilepsy, Juvenile; Prospective Studies; Treatment Outcome; Triazines; Valproic Acid | 2013 |
Pharmacokinetics of lamotrigine in paediatric and young adult epileptic patients--nonlinear mixed effects modelling approach.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Interactions; Drug Monitoring; Epilepsy; Female; Humans; Lamotrigine; Male; Models, Biological; Nonlinear Dynamics; Triazines; Valproic Acid; Young Adult | 2014 |
Time to 12-month remission and treatment failure for generalised and unclassified epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Child; Electroencephalography; Epilepsy, Generalized; Female; Fructose; Humans; Lamotrigine; Magnetic Resonance Imaging; Male; Odds Ratio; Predictive Value of Tests; Regression Analysis; Remission Induction; Seizures; Time Factors; Tomography, X-Ray Computed; Topiramate; Treatment Failure; Triazines; Valproic Acid | 2014 |
Treatment outcome after failure of a first antiepileptic drug.
Topics: Adolescent; Adult; Anticonvulsants; Epilepsy; Female; Fructose; Humans; Lamotrigine; Male; Middle Aged; Time Factors; Topiramate; Treatment Failure; Treatment Outcome; Triazines; Valproic Acid; Young Adult | 2014 |
Efficacy and safety of ezogabine/retigabine as adjunctive therapy to specified single antiepileptic medications in an open-label study of adults with partial-onset seizures.
Topics: Aged; Anticonvulsants; Carbamates; Carbamazepine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsies, Partial; Female; Humans; Kaplan-Meier Estimate; Lamotrigine; Levetiracetam; Male; Middle Aged; Oxcarbazepine; Phenylenediamines; Piracetam; Seizures; Treatment Outcome; Triazines; Valproic Acid | 2015 |
Influence of valproic acid concentration and polymorphism of UGT1A4*3, UGT2B7 -161C > T and UGT2B7*2 on serum concentration of lamotrigine in Chinese epileptic children.
Topics: Adolescent; Anticonvulsants; Asian People; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Female; Genotype; Glucuronosyltransferase; Humans; Lamotrigine; Male; Polymorphism, Single Nucleotide; Triazines; Valproic Acid | 2015 |
Cognitive effects of adjunctive perampanel for partial-onset seizures: A randomized trial.
Topics: Acetamides; Adolescent; Anticonvulsants; Attention; Carbamazepine; Child; Cognition; Double-Blind Method; Drug Therapy, Combination; Epilepsies, Partial; Female; Fructose; Humans; Lacosamide; Lamotrigine; Levetiracetam; Male; Memory, Short-Term; Neuropsychological Tests; Nitriles; Oxcarbazepine; Piracetam; Pyridones; Topiramate; Treatment Outcome; Triazines; Valproic Acid | 2016 |
Prediction of an Optimal Dose of Lamotrigine for Augmentation Therapy in Treatment-Resistant Depressive Disorder From Plasma Lamotrigine Concentration at Week 2.
Topics: Adult; Antidepressive Agents; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Chromatography, High Pressure Liquid; Depressive Disorder, Major; Depressive Disorder, Treatment-Resistant; Dose-Response Relationship, Drug; Drug Monitoring; Drug Therapy, Combination; Female; Humans; Lamotrigine; Male; Middle Aged; Treatment Outcome; Triazines; Valproic Acid | 2016 |
Association of UGT2B7 and UGT1A4 Polymorphisms with Serum Concentration of Antiepileptic Drugs in Children.
Topics: Adolescent; Anticonvulsants; Asian People; Base Sequence; Child; Child, Preschool; Epilepsy; Female; Genetic Association Studies; Glucuronosyltransferase; Humans; Lamotrigine; Male; Multivariate Analysis; Polymorphism, Single Nucleotide; Regression Analysis; Triazines; Valproic Acid | 2016 |
Evaluate the effects of long-term valproic acid treatment on metabolic profiles in newly diagnosed or untreated female epileptic patients: A prospective study.
Topics: Adiponectin; Adolescent; Adult; Anticonvulsants; Blood Glucose; Body Mass Index; Cholesterol; Cholesterol, HDL; Epilepsy; Female; Humans; Insulin Resistance; Lamotrigine; Metabolism, Inborn Errors; Prospective Studies; Triazines; Triglycerides; Valproic Acid; Weight Gain; Young Adult | 2017 |
Correlation between the Efficacy of Lamotrigine and the Serum Lamotrigine Level during the Remission Phase of Acute Bipolar II Depression: A Naturalistic and Unblinded Prospective Pilot Study.
Topics: Adult; Aged; Antidepressive Agents; Bipolar Disorder; Drug Therapy, Combination; Female; Humans; Lamotrigine; Male; Middle Aged; Pilot Projects; Prospective Studies; Remission Induction; Treatment Outcome; Triazines; Valproic Acid | 2017 |
Pretreatment behavior and subsequent medication effects in childhood absence epilepsy.
Topics: Adolescent; Anticonvulsants; Checklist; Child; Child Behavior Disorders; Child, Preschool; Cross-Over Studies; Double-Blind Method; Electroencephalography; Epilepsy, Absence; Ethosuximide; Female; Follow-Up Studies; Humans; Lamotrigine; Male; Neuropsychological Tests; Outcome Assessment, Health Care; Triazines; Valproic Acid | 2017 |
Evaluate the effects of antiepileptic drugs on reproductive endocrine system in newly diagnosed female epileptic patients receiving either Valproate or Lamotrigine monotherapy: A prospective study.
Topics: Adolescent; Adult; Anticonvulsants; Endocrine System; Epilepsy; Female; Follow-Up Studies; Hormones; Humans; Lamotrigine; Menstruation Disturbances; Ovary; Polycystic Ovary Syndrome; Risk Factors; Valproic Acid; Young Adult | 2018 |
Unblinded, randomized multicenter trial comparing lamotrigine and valproate combination with controlled-release carbamazepine monotherapy as initial drug regimen in untreated epilepsy.
Topics: Adult; Anticonvulsants; Carbamazepine; Delayed-Action Preparations; Drug Therapy, Combination; Epilepsy; Female; Humans; Lamotrigine; Male; Triazines; Valproic Acid | 2018 |
Effect of lamotrigine on cognitive function and serum inflammatory factors in patients with depression of recurrent bipolar disorder.
Topics: Adult; Anticonvulsants; Bipolar Disorder; Cognition; Female; Humans; Inflammation Mediators; Interleukin-1beta; Interleukin-6; Intramolecular Oxidoreductases; Lamotrigine; Macrophage Migration-Inhibitory Factors; Male; Middle Aged; Recurrence; Trail Making Test; Valproic Acid; Young Adult | 2018 |
Sequential Multiple Assignment Randomized Treatment (SMART) for Bipolar Disorder at Any Phase of Illness and at least Mild Symptom Severity.
Topics: Antipsychotic Agents; Bipolar Disorder; Double-Blind Method; Drug Therapy, Combination; Humans; Lamotrigine; Lithium; Quetiapine Fumarate; Treatment Outcome; Valproic Acid | 2020 |
Lamotrigine versus levetiracetam or zonisamide for focal epilepsy and valproate versus levetiracetam for generalised and unclassified epilepsy: two SANAD II non-inferiority RCTs.
Topics: Child, Preschool; Cost-Benefit Analysis; Epilepsies, Partial; Epilepsy; Female; Humans; Lamotrigine; Levetiracetam; Quality of Life; Valproic Acid; Zonisamide | 2021 |
Value of Group Intervention on Prognosis of Quality of Life in Epileptic Patients Treated With Sodium Valproate and Lamotrigine.
Topics: Epilepsy; Humans; Lamotrigine; Prognosis; Quality of Life; Valproic Acid | 2023 |
450 other study(ies) available for valproic acid and lamotrigine
Article | Year |
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Synthesis and anticonvulsant activity of a new class of 2-[(arylalky)amino]alkanamide derivatives.
Topics: Alanine; Animals; Anticonvulsants; Benzylamines; Bicuculline; Drug Design; Electroshock; Indicators and Reagents; Male; Mice; Mice, Inbred ICR; Models, Molecular; Molecular Structure; Motor Activity; Picrotoxin; Postural Balance; Rats; Rats, Inbred Strains; Seizures; Structure-Activity Relationship; Strychnine | 1998 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity.
Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship | 2003 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Inhibition of aquaporin 4 by antiepileptic drugs.
Topics: Animals; Anticonvulsants; Aquaporin 4; Computer Simulation; Drug Evaluation, Preclinical; Humans; Oocytes; Protein Binding; Thermodynamics; Xenopus | 2009 |
Novel, broad-spectrum anticonvulsants containing a sulfamide group: advancement of N-((benzo[b]thien-3-yl)methyl)sulfamide (JNJ-26990990) into human clinical studies.
Topics: Amides; Animals; Anticonvulsants; Carbonic Anhydrase II; Cell Line; Clinical Trials as Topic; Drug Evaluation, Preclinical; Female; Humans; Male; Mice; Rats; Sulfonamides; Thiophenes | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility | 2010 |
Synthesis and anticonvulsant activity of trans- and cis-2-(2,6-dimethylphenoxy)-N-(2- or 4-hydroxycyclohexyl)acetamides and their amine analogs.
Topics: Acetamides; Amines; Animals; Anticonvulsants; Mice; Rats; Seizures | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Novel, broad-spectrum anticonvulsants containing a sulfamide group: pharmacological properties of (S)-N-[(6-chloro-2,3-dihydrobenzo[1,4]dioxin-2-yl)methyl]sulfamide (JNJ-26489112).
Topics: Absorption; Amides; Animals; Anticonvulsants; Dioxanes; Dogs; Drug Evaluation, Preclinical; Drug Resistance; Epilepsy; Female; Humans; Male; Mice; Rats; Sulfonamides | 2013 |
Chlorophenoxy aminoalkyl derivatives as histamine H(3)R ligands and antiseizure agents.
Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Electroshock; Humans; Ligands; Male; Mice; Models, Molecular; Molecular Structure; Rats; Rats, Sprague-Dawley; Receptors, Histamine H3; Seizures; Structure-Activity Relationship | 2016 |
What to do when the first anticonvulsant does not work.
Topics: Aminocaproates; Anticonvulsants; Carbamazepine; Epilepsy; Humans; Lamotrigine; Phenytoin; Treatment Outcome; Triazines; Valproic Acid; Vigabatrin | 1992 |
Sodium valproate acutely inhibits lamotrigine metabolism.
Topics: Adult; Anticonvulsants; Drug Interactions; Glucuronates; Humans; Lamotrigine; Liver; Male; Triazines; Valproic Acid | 1992 |
Use of antiepileptic drugs in childhood epilepsy.
Topics: Adult; Aminocaproates; Anticonvulsants; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Humans; Infant; Lamotrigine; Prognosis; Risk Factors; Triazines; Valproic Acid; Vigabatrin | 1991 |
Juvenile myoclonic epilepsy.
Topics: Adolescent; Age of Onset; Animals; Anticonvulsants; Child; Circadian Rhythm; Clonazepam; Cricetinae; Electroencephalography; Epilepsies, Myoclonic; Epilepsy, Tonic-Clonic; Female; Humans; Lamotrigine; Life Style; Pregnancy; Pregnancy Complications; Triazines; Valproic Acid | 1995 |
Lamotrigine versus carbamazepine in epilepsy.
Topics: Adult; Anticonvulsants; Clonazepam; Epilepsy, Generalized; Epilepsy, Tonic-Clonic; Humans; Lamotrigine; Male; Stevens-Johnson Syndrome; Triazines; Valproic Acid | 1995 |
Lamotrigine as an add-on drug in typical absence seizures.
Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy, Generalized; Female; Follow-Up Studies; Humans; Infant; Lamotrigine; Male; Middle Aged; Retrospective Studies; Treatment Outcome; Triazines; Valproic Acid | 1995 |
Juvenile myoclonic epilepsy: diagnosis, management and outcome.
Topics: Adolescent; Adult; Alcohol Drinking; Anticonvulsants; Carbamazepine; Epilepsies, Myoclonic; Female; Humans; Lamotrigine; Life Style; Male; Middle Aged; Phenytoin; Prognosis; Sleep Deprivation; Stress, Physiological; Time Factors; Treatment Outcome; Triazines; Valproic Acid; Weight Gain | 1995 |
Therapeutic interaction of lamotrigine and sodium valproate in intractable myoclonic epilepsy.
Topics: Adolescent; Anticonvulsants; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Electroencephalography; Epilepsies, Myoclonic; Female; Humans; Lamotrigine; Treatment Outcome; Triazines; Valproic Acid | 1994 |
Interaction of lamotrigine with sodium valproate.
Topics: Adolescent; Anticonvulsants; Child; Drug Synergism; Epilepsy, Absence; Humans; Lamotrigine; Triazines; Valproic Acid | 1993 |
Interaction of lamotrigine with sodium valproate.
Topics: Adult; Aged; Anticonvulsants; Child; Drug Interactions; Drug Therapy, Combination; Female; Humans; Lamotrigine; Male; Middle Aged; Seizures; Triazines; Valproic Acid | 1993 |
Disabling tremor after lamotrigine with sodium valproate.
Topics: Anticonvulsants; Drug Interactions; Epilepsy, Generalized; Epilepsy, Tonic-Clonic; Humans; Lamotrigine; Phenytoin; Tremor; Triazines; Valproic Acid | 1993 |
Lamotrigine encephalopathy.
Topics: Anticonvulsants; Astrocytoma; Brain Diseases; Brain Neoplasms; Drug Interactions; Female; Frontal Lobe; Humans; Lamotrigine; Middle Aged; Seizures; Triazines; Valproic Acid | 1996 |
Lamotrigine potentiates the antiseizure activity of some anticonvulsants in DBA/2 mice.
Topics: Acoustic Stimulation; Animals; Anticonvulsants; Diazepam; Drug Synergism; Female; Lamotrigine; Male; Mice; Mice, Inbred DBA; Phenytoin; Seizures; Triazines; Valproic Acid | 1996 |
Allergic skin rash with lamotrigine and concomitant valproate therapy: evidence for an increased risk.
Topics: Adolescent; Adult; Anticonvulsants; Drug Eruptions; Female; Humans; Lamotrigine; Male; Middle Aged; Risk Factors; Triazines; Valproic Acid | 1996 |
The use of lamotrigine in juvenile myoclonic epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Epilepsies, Myoclonic; Female; Humans; Lamotrigine; Triazines; Valproic Acid | 1996 |
Addition of lamotrigine to valproate may enhance efficacy in the treatment of bipolar affective disorder.
Topics: Adult; Anticonvulsants; Bipolar Disorder; Drug Therapy, Combination; Humans; Lamotrigine; Male; Triazines; Valproic Acid | 1996 |
Nonconvulsive status epilepticus with generalized 'fast activity'.
Topics: Alpha Rhythm; Anticonvulsants; Cerebral Cortex; Diagnosis, Differential; Drug Therapy, Combination; Electroencephalography; Epilepsy, Generalized; Epilepsy, Tonic-Clonic; Humans; Lamotrigine; Male; Mental Recall; Middle Aged; Status Epilepticus; Triazines; Valproic Acid | 1997 |
Valproate and lamotrigine in migraine.
Topics: Calcium Channel Blockers; Humans; Lamotrigine; Migraine Disorders; Triazines; Valproic Acid | 1997 |
Lamotrigine treatment of rapid cycling bipolar disorder.
Topics: Adult; Aged; Anticonvulsants; Bipolar Disorder; Drug Administration Schedule; Drug Eruptions; Drug Therapy, Combination; Humans; Lamotrigine; Triazines; Valproic Acid | 1997 |
Lamotrigine-induced Stevens-Johnson syndrome: demonstration of specific lymphocyte reactivity in vitro.
Topics: Adult; Anticonvulsants; Concanavalin A; Drug Eruptions; Drug Therapy, Combination; Half-Life; Humans; Lamotrigine; Liver; Lymphocyte Activation; Lymphocytes; Male; Risk Factors; Stevens-Johnson Syndrome; Triazines; Valproic Acid | 1997 |
An open study of lamotrigine in refractory bipolar depression.
Topics: Adolescent; Adult; Anticonvulsants; Antidepressive Agents; Bipolar Disorder; Cohort Studies; Depressive Disorder; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Lamotrigine; Male; Personality Inventory; Psychiatric Status Rating Scales; Treatment Outcome; Triazines; Valproic Acid | 1997 |
Multiorgan dysfunction and disseminated intravascular coagulation in children receiving lamotrigine and valproic acid.
Topics: Anticonvulsants; Child; Child, Preschool; Disseminated Intravascular Coagulation; Drug Interactions; Drug Therapy, Combination; Female; Humans; Lamotrigine; Male; Multiple Organ Failure; Triazines; Valproic Acid | 1997 |
Lamotrigine and toxic epidermal necrolysis.
Topics: Anticonvulsants; Drug Therapy, Combination; Humans; Infant; Lamotrigine; Male; Stevens-Johnson Syndrome; Triazines; Valproic Acid | 1997 |
[Lamotrigine (Lamictal)].
Topics: Anticonvulsants; Brain; Child; Child, Preschool; Drug Combinations; Drug Eruptions; Epilepsies, Partial; Epilepsy; Epilepsy, Generalized; Excitatory Amino Acid Antagonists; Humans; Lamotrigine; Sodium Channel Blockers; Triazenes; Triazines; Valproic Acid | 1997 |
Valproate, lamotrigine, and insulin-mediated risks in women with epilepsy.
Topics: Analysis of Variance; Anticonvulsants; Cholesterol, HDL; Epilepsy; Female; Follow-Up Studies; Humans; Hyperandrogenism; Hyperinsulinism; Insulin; Lamotrigine; Menstrual Cycle; Ovary; Polycystic Ovary Syndrome; Risk Assessment; Time Factors; Triazines; Ultrasonography; Valproic Acid | 1998 |
Does antiepileptic therapy affect immune response?
Topics: Adolescent; Adult; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Carbamazepine; Clobazam; Cytokines; Drug Therapy, Combination; Epilepsy; Felbamate; Female; Humans; Immunoglobulin A; Immunoglobulin G; Immunoglobulin M; Lamotrigine; Male; Phenobarbital; Phenylcarbamates; Phenytoin; Propylene Glycols; Receptors, Interleukin-2; Triazines; Valproic Acid | 1998 |
New perspectives in the treatment of acute mania: a single case report.
Topics: Anticonvulsants; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Female; Humans; Infusions, Intravenous; Lamotrigine; Middle Aged; Treatment Outcome; Triazines; Valproic Acid | 1998 |
Lamotrigine inhibits monoamine uptake in vitro and modulates 5-hydroxytryptamine uptake in rats.
Topics: Acetates; Amines; Animals; Anticonvulsants; Biogenic Amines; Blood Platelets; Brain; Carbamazepine; Cyclohexanecarboxylic Acids; Dopamine; Dopamine Uptake Inhibitors; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Lithium; Male; Norepinephrine; p-Chloroamphetamine; Phenytoin; Rats; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Agents; Serotonin Syndrome; Synaptosomes; Tetrodotoxin; Triazines; Valproic Acid; Zonisamide | 1998 |
Carbamazepine-10,11-epoxide in therapeutic drug monitoring.
Topics: Adult; Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Drug Interactions; Drug Monitoring; Female; Fluorescence Polarization Immunoassay; Humans; Lamotrigine; Phenytoin; Sodium Channels; Triazines; Valproic Acid | 1998 |
Lamotrigine and therapeutic drug monitoring: retrospective survey following the introduction of a routine service.
Topics: Anticonvulsants; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Epilepsy; Health Care Surveys; Humans; Lamotrigine; Retrospective Studies; Triazines; Valproic Acid | 1998 |
Lamotrigine drug interactions in a TDM material.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Female; Humans; Lamotrigine; Male; Middle Aged; Phenobarbital; Phenytoin; Triazines; Valproic Acid | 1999 |
Influence of oxcarbazepine and methsuximide on lamotrigine concentrations in epileptic patients with and without valproic acid comedication: results of a retrospective study.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Child; Drug Interactions; Drug Therapy, Combination; Female; Humans; Lamotrigine; Male; Middle Aged; Oxcarbazepine; Regression Analysis; Retrospective Studies; Succinimides; Triazines; Valproic Acid | 1999 |
A case of fever following antiepileptic treatment.
Topics: Adult; Anticonvulsants; Body Temperature Regulation; Carbamazepine; Drug Therapy, Combination; Epilepsy, Complex Partial; Female; Fever of Unknown Origin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Oxcarbazepine; Triazines; Valproic Acid; Vigabatrin | 1999 |
Mood stabilizer combinations for bipolar disorder.
Topics: Acetates; Adolescent; Age Factors; Amines; Antimanic Agents; Bipolar Disorder; Child; Cyclohexanecarboxylic Acids; Drug Eruptions; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Lithium; Triazines; Valproic Acid | 1999 |
The efficacy of valproate-lamotrigine comedication in refractory complex partial seizures: evidence for a pharmacodynamic interaction.
Topics: Adult; Anticonvulsants; Drug Interactions; Drug Therapy, Combination; Epilepsy, Complex Partial; Female; Humans; Lamotrigine; Male; Middle Aged; Treatment Outcome; Triazines; Valproic Acid | 1999 |
Photo Quiz.
Topics: Aged; Anticonvulsants; Drug Interactions; Epilepsy; Female; Humans; Lamotrigine; Skin; Stevens-Johnson Syndrome; Triazines; Valproic Acid | 1999 |
Stevens-Johnson syndrome and antiepileptics.
Topics: Adult; Anticonvulsants; Child; Drug Therapy, Combination; Epilepsy; Humans; Lamotrigine; Stevens-Johnson Syndrome; Triazines; Valproic Acid | 1999 |
Factors influencing the incidence of lamotrigine-related skin rash.
Topics: Adolescent; Adult; Anticonvulsants; Child; Dose-Response Relationship, Drug; Drug Therapy, Combination; England; Epilepsy; Exanthema; Female; Humans; Incidence; Lamotrigine; Male; Middle Aged; Practice Guidelines as Topic; Retrospective Studies; Risk Factors; Sex Factors; Triazines; Valproic Acid | 1999 |
Lamotrigine as prophylaxis against steroid-induced mania.
Topics: Adult; Anti-Inflammatory Agents; Antimanic Agents; Bipolar Disorder; Contraindications; Female; Humans; Lamotrigine; Lithium; Nephritis, Interstitial; Prednisone; Triazines; Valproic Acid | 1999 |
Paradoxic reaction to lamotrigine in a child with benign focal epilepsy of childhood with centrotemporal spikes.
Topics: Acute Disease; Anticonvulsants; Carbamazepine; Child; Electroencephalography; Epilepsy, Absence; Epilepsy, Rolandic; Female; Humans; Lamotrigine; Triazines; Valproic Acid | 1999 |
Lupus anticoagulant induced by the combination of valproate and lamotrigine.
Topics: Antibodies, Anticardiolipin; Anticonvulsants; Child, Preschool; Dose-Response Relationship, Drug; Drug Therapy, Combination; Enzyme-Linked Immunosorbent Assay; Epilepsy, Absence; Humans; Lamotrigine; Lupus Coagulation Inhibitor; Lupus Erythematosus, Systemic; Male; Triazines; Valproic Acid | 1999 |
Valproic acid dosing recommendations questioned.
Topics: Adult; Age Factors; Anticonvulsants; Drug Combinations; Drug Interactions; Epilepsy; Half-Life; Humans; Lamotrigine; Middle Aged; Triazines; Valproic Acid | 2000 |
Severe hypersensitivity syndrome to lamotrigine confirmed by lymphocyte stimulation in vitro.
Topics: Adult; Anticonvulsants; Drug Hypersensitivity; Drug Therapy, Combination; Humans; Immunologic Tests; Lamotrigine; Lymphocyte Activation; Male; Triazines; Valproic Acid | 2000 |
Improved sexual function in three men taking lamotrigine for epilepsy.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsies, Partial; Epilepsy, Complex Partial; Epilepsy, Temporal Lobe; Erectile Dysfunction; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Middle Aged; Phenobarbital; Phenytoin; Sexual Dysfunctions, Psychological; Triazines; Valproic Acid | 2000 |
Tolerance to the anticonvulsant effects of lamotrigine on amygdala kindled seizures: cross-tolerance to carbamazepine but not valproate or diazepam.
Topics: Amygdala; Animals; Anticonvulsants; Carbamazepine; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Drug Tolerance; Electric Stimulation; Electrodes, Implanted; Kindling, Neurologic; Lamotrigine; Male; Rats; Rats, Sprague-Dawley; Seizures; Triazines; Valproic Acid | 2000 |
[Effectiveness and tolerance of adjunctive treatment of lamotrigine and conversion to monotherapy in pediatric patients with epilepsy. Preliminary studies].
Topics: Adolescent; Adult; Anticonvulsants; Child; Drug Tolerance; Electroencephalography; Epilepsy; Female; Humans; Lamotrigine; Male; Triazines; Valproic Acid | 2000 |
Valproate, hyperandrogenism, and polycystic ovaries: a report of 3 cases.
Topics: Adolescent; Adult; Anticonvulsants; Body Weight; Electroencephalography; Epilepsy; Female; Humans; Hyperandrogenism; Lamotrigine; Menstruation Disturbances; Ovary; Polycystic Ovary Syndrome; Testosterone; Treatment Outcome; Triazines; Ultrasonography; Valproic Acid | 2000 |
Lamotrigine and clozapine for bipolar disorder.
Topics: Antidepressive Agents; Antipsychotic Agents; Bipolar Disorder; Clozapine; Drug Therapy, Combination; Humans; Lamotrigine; Male; Middle Aged; Treatment Outcome; Triazines; Valproic Acid | 2000 |
Prolonged toxic epidermal necrolysis due to Lamotrigine.
Topics: Adult; Anticonvulsants; Drug Interactions; Humans; Lamotrigine; Male; Seizures; Stevens-Johnson Syndrome; Triazines; Valproic Acid | 2000 |
Stevens-Johnson syndrome associated with concomitant use of lamotrigine and valproic acid.
Topics: Adult; Anticonvulsants; Antimanic Agents; Drug Therapy, Combination; Female; Humans; Lamotrigine; Psychotic Disorders; Stevens-Johnson Syndrome; Triazines; Valproic Acid | 2000 |
Exacerbation of juvenile myoclonic epilepsy with lamotrigine.
Topics: Adolescent; Adult; Anticonvulsants; Female; Humans; Lamotrigine; Male; Myoclonic Epilepsy, Juvenile; Triazines; Valproic Acid | 2000 |
Idiopathic generalized epilepsy presenting with hemiconvulsive seizures.
Topics: Adolescent; Anticonvulsants; Child; Comorbidity; Electroencephalography; Epilepsy, Frontal Lobe; Epilepsy, Generalized; Epilepsy, Partial, Motor; Female; Humans; Lamotrigine; Male; Treatment Outcome; Triazines; Valproic Acid | 2000 |
Valproate and other anticonvulsants for psychiatric disorders.
Topics: Abnormalities, Drug-Induced; Acetates; Adult; Amines; Anti-Anxiety Agents; Anticonvulsants; Bipolar Disorder; Carbamazepine; Cognition Disorders; Cyclohexanecarboxylic Acids; Dizziness; Dose-Response Relationship, Drug; Drug Therapy, Combination; Fructose; Gabapentin; gamma-Aminobutyric Acid; Heart Defects, Congenital; Humans; Lamotrigine; Nausea; Obesity; Stevens-Johnson Syndrome; Topiramate; Triazines; Valproic Acid | 2000 |
Evaluating the tolerability of the newer mood stabilizers.
Topics: Acetates; Amines; Anticonvulsants; Bipolar Disorder; Central Nervous System Diseases; Cyclohexanecarboxylic Acids; Drug Information Services; Fructose; Gabapentin; gamma-Aminobutyric Acid; Gastrointestinal Diseases; Humans; Incidence; Lamotrigine; Mental Disorders; Neurotoxicity Syndromes; Topiramate; Triazines; Valproic Acid | 2001 |
Valproate, but not lamotrigine, induces ovarian morphological changes in Wistar rats.
Topics: Administration, Oral; Animals; Anticonvulsants; Body Temperature; Body Weight; Female; Immunoenzyme Techniques; Lamotrigine; Organ Size; Ovary; Rats; Rats, Wistar; Triazines; Tumor Suppressor Protein p53; Valproic Acid | 2001 |
Case reports.
Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Anticonvulsants; Child; Diagnosis, Differential; Epilepsy; Female; Humans; Hyperandrogenism; Lamotrigine; Polycystic Ovary Syndrome; Triazines; Valproic Acid | 2001 |
Absence epilepsy with fast rhythmic discharges during sleep: an intermediary form of generalized epilepsy?
Topics: Adult; Age of Onset; Anticonvulsants; Cerebral Cortex; Child; Child, Preschool; Diagnosis, Differential; Drug Resistance; Electroencephalography; Epilepsy; Epilepsy, Absence; Epilepsy, Generalized; Female; Humans; Lamotrigine; Male; Middle Aged; Prognosis; Retrospective Studies; Sleep; Triazines; Valproic Acid; Wakefulness | 2001 |
Introduction: the role of anticonvulsants as mood stabilizers.
Topics: Anticonvulsants; Bipolar Disorder; Depressive Disorder; Humans; Lamotrigine; Lithium; Terminology as Topic; Triazines; Valproic Acid | 2001 |
Hormone profiles in young adults with epilepsy treated with sodium valproate or lamotrigine monotherapy.
Topics: Adult; Anticonvulsants; Blood Glucose; Body Mass Index; Comorbidity; Dehydroepiandrosterone; Epilepsy; Female; Humans; Hyperinsulinism; Insulin; Lamotrigine; Lipids; Male; Menstruation Disturbances; Obesity; Polycystic Ovary Syndrome; Sex Factors; Testosterone; Triazines; Triglycerides; Valproic Acid | 2001 |
Stupor from lamotrigine toxicity.
Topics: Anticonvulsants; Coma; Drug Overdose; Epilepsy, Complex Partial; Female; Humans; Lamotrigine; Middle Aged; Neurotoxicity Syndromes; Suicide, Attempted; Triazines; Valproic Acid | 2001 |
Long-term valproate and lamotrigine treatment may be a marker for reduced growth and bone mass in children with epilepsy.
Topics: Adolescent; Anticonvulsants; Bone and Bones; Bone Density; Bone Diseases, Developmental; Bone Diseases, Metabolic; Calcium, Dietary; Child; Child Development; Child, Preschool; Diet; Epilepsy; Female; Growth; Humans; Lamotrigine; Male; Osteocalcin; Physical Exertion; Triazines; Valproic Acid; Vitamin D | 2001 |
Effectiveness of first antiepileptic drug.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy; Female; Humans; Lamotrigine; Male; Treatment Outcome; Triazines; Valproic Acid | 2001 |
Population pharmacokinetics of lamotrigine.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Drug Interactions; Female; Humans; Lamotrigine; Male; Metabolic Clearance Rate; Middle Aged; Triazines; Valproic Acid | 2001 |
Reversible aphasic disorder induced by lamotrigine in atypical benign childhood epilepsy.
Topics: Anticonvulsants; Aphasia; Child; Electroencephalography; Epilepsy, Absence; Female; Humans; Lamotrigine; Triazines; Valproic Acid; Wechsler Scales | 2001 |
Influence of some beta-adrenoceptor antagonists on the anticonvulsant potency of antiepileptic drugs against audiogenic seizures in DBA/2 mice.
Topics: Acoustic Stimulation; Adrenergic beta-Antagonists; Animals; Anticonvulsants; Atenolol; Body Temperature; Carbamazepine; Epilepsy, Reflex; Female; Lamotrigine; Male; Metoprolol; Mice; Mice, Inbred DBA; Motor Activity; Phenobarbital; Propanolamines; Propranolol; Stereoisomerism; Triazines; Valproic Acid | 2002 |
Antiepileptic drugs and agents that inhibit voltage-gated sodium channels prevent NMDA antagonist neurotoxicity.
Topics: Animals; Anticonvulsants; Carbamazepine; Dizocilpine Maleate; Drug Interactions; Excitatory Amino Acid Antagonists; Female; Ion Channel Gating; Lamotrigine; Neurotransmitter Agents; Phenytoin; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sodium Channels; Triazines; Valproic Acid | 2002 |
Mild generalized epilepsy and developmental disorder associated with large inv dup(15).
Topics: Adult; Age of Onset; Angelman Syndrome; Anticonvulsants; Chromosome Aberrations; Chromosome Inversion; Chromosomes, Human, Pair 15; Electroencephalography; Epilepsy, Absence; Epilepsy, Generalized; Female; Gene Duplication; Humans; In Situ Hybridization, Fluorescence; Intellectual Disability; Lamotrigine; Male; Phenotype; Prader-Willi Syndrome; Severity of Illness Index; Treatment Outcome; Triazines; Valproic Acid | 2002 |
Effects of antiepileptic drugs on induced epileptiform activity in a rat model of dysplasia.
Topics: 4-Aminopyridine; Action Potentials; Animals; Animals, Newborn; Anticonvulsants; Carbamazepine; Disease Models, Animal; Electroencephalography; Epilepsy; Ethosuximide; Female; Hippocampus; In Vitro Techniques; Lamotrigine; Methylazoxymethanol Acetate; Phenobarbital; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Triazines; Valproic Acid | 2002 |
Does lamotrigine influence valproate concentrations?
Topics: Adolescent; Adult; Analysis of Variance; Child; Child, Preschool; Drug Interactions; Epilepsy; Female; Humans; Lamotrigine; Male; Regression Analysis; Triazines; Valproic Acid | 2002 |
Non convulsive status epilepticus after replacement of valproate with lamotrigine.
Topics: Adult; Aged; Anticoagulants; Benzodiazepines; Electroencephalography; Epilepsy, Generalized; Female; Humans; Lamotrigine; Middle Aged; Retrospective Studies; Status Epilepticus; Substance Withdrawal Syndrome; Triazines; Valproic Acid | 2002 |
Synergistic interaction between valproate and lamotrigine against seizures induced by 4-aminopyridine and pentylenetetrazole in mice.
Topics: Animals; Brain; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Lamotrigine; Male; Mice; Pentylenetetrazole; Seizures; Triazines; Valproic Acid | 2002 |
Lamotrigine use in geriatric patients with bipolar depression.
Topics: Aged; Aged, 80 and over; Antimanic Agents; Bipolar Disorder; Depressive Disorder; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Lamotrigine; Lithium Chloride; Male; Triazines; Valproic Acid | 2002 |
Therapeutic drug monitoring of lamotrigine in patients suffering from resistant partial seizures.
Topics: Adult; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug Interactions; Drug Monitoring; Drug Resistance; Drug Therapy, Combination; Epilepsies, Partial; Female; Humans; Lamotrigine; Male; Middle Aged; Treatment Outcome; Triazines; Valproic Acid | 2002 |
Thoughts on Aldenkamp et al.'s article.
Topics: Anticonvulsants; Bias; Cognition; Dose-Response Relationship, Drug; Functional Laterality; Humans; Lamotrigine; Neuropsychological Tests; Psychomotor Performance; Triazines; Valproic Acid | 2002 |
Valproic acid and lamotrigine treatment during pregnancy. The risk of chromosomal abnormality.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adult; Anticonvulsants; Chromosome Aberrations; Chromosomes, Human, X; Cleft Palate; Epilepsy; Female; Fetal Growth Retardation; Humans; Infant; Infant, Newborn; Karyotyping; Lamotrigine; Pedigree; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Triazines; Valproic Acid | 2003 |
Neuroprotective effects of anticonvulsants in rat hippocampal slice cultures exposed to oxygen/glucose deprivation.
Topics: Acetates; Amines; Animals; Anticonvulsants; Carbamates; Carbamazepine; Cell Death; Cells, Cultured; Chlordiazepoxide; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Ethosuximide; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Glucose; Hippocampus; Hypoxia; Ischemia; Lamotrigine; Levetiracetam; Midazolam; Neurons; Neuroprotective Agents; Nipecotic Acids; Oxcarbazepine; Phenobarbital; Phenylcarbamates; Phenylenediamines; Phenytoin; Piracetam; Propylene Glycols; Rats; Rats, Wistar; Tiagabine; Triazines; Valproic Acid | 2003 |
Comparison of lamotrigine and valproate with respect to quality of life.
Topics: Anticonvulsants; Epilepsy; Humans; Lamotrigine; Quality of Life; Triazines; Valproic Acid | 2003 |
Uptake of GABA and activity of GABA-transaminase in platelets from epileptic patients.
Topics: 4-Aminobutyrate Transaminase; Adult; Anticonvulsants; Blood Platelets; Case-Control Studies; Dose-Response Relationship, Drug; Epilepsy; Female; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Myoclonic Epilepsy, Juvenile; Triazines; Valproic Acid | 2003 |
Neurotoxicity following addition of intravenous valproate to lamotrigine therapy.
Topics: Administration, Oral; Adult; Ammonia; Anticonvulsants; Confusion; Drug Interactions; Drug Therapy, Combination; Epilepsy, Absence; Epilepsy, Generalized; Female; Glucuronosyltransferase; Humans; Inactivation, Metabolic; Injections, Intravenous; Lamotrigine; Middle Aged; Status Epilepticus; Triazines; Valproic Acid | 2003 |
Higher androgens and weight gain with valproate compared with lamotrigine for epilepsy.
Topics: Adult; Analysis of Variance; Androgens; Confidence Intervals; Cross-Sectional Studies; Epilepsy; Female; Humans; Lamotrigine; Triazines; Valproic Acid; Weight Gain | 2003 |
Lamotrigine and valproate: efficacy of co-administration in a pediatric population.
Topics: Adolescent; Ambulatory Care; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Female; Follow-Up Studies; Humans; Infant; Lamotrigine; Male; Triazines; Valproic Acid | 2003 |
Suspected lamotrigine-induced toxic epidermal necrolysis.
Topics: Adult; Anticonvulsants; Drug Therapy, Combination; Female; Humans; Lamotrigine; Myoclonic Epilepsy, Juvenile; Skin; Stevens-Johnson Syndrome; Triazines; Valproic Acid | 2003 |
A study of anticonvulsant medication on ovarian function in a group of women with epilepsy who have only ever taken one anticonvulsant compared with a group of women without epilepsy.
Topics: Anticonvulsants; Carbamazepine; Case-Control Studies; Epilepsy; Female; Follicle Stimulating Hormone; Humans; Lamotrigine; Luteinizing Hormone; Magnetic Resonance Imaging; Menstrual Cycle; Ovary; Polycystic Ovary Syndrome; Prolactin; Testosterone; Triazines; Valproic Acid | 2003 |
The Australian registry of anti-epileptic drugs in pregnancy: experience after 30 months.
Topics: Abortion, Induced; Anticonvulsants; Australia; Carbamazepine; Cohort Studies; Congenital Abnormalities; Epilepsy; Female; Humans; Infant; Infant, Newborn; Interviews as Topic; Lamotrigine; Pregnancy; Pregnancy Complications; Pregnancy Trimester, First; Prospective Studies; Registries; Telephone; Triazines; Valproic Acid | 2003 |
The relationship between treatment with valproate, lamotrigine, and topiramate and the prognosis of the idiopathic generalised epilepsies.
Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Databases, Factual; Electroencephalography; Epilepsy; Female; Fructose; Humans; Lamotrigine; Male; Retrospective Studies; Topiramate; Treatment Outcome; Triazines; Valproic Acid | 2004 |
Interaction between anticonvulsants and human placental carnitine transporter.
Topics: Acetates; Amines; Aminoisobutyric Acids; Anticonvulsants; Carnitine; Carrier Proteins; Culture Techniques; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Administration Schedule; Epilepsy; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Models, Biological; Nipecotic Acids; Organic Cation Transport Proteins; Phenytoin; Placenta; Pregnancy; Pregnancy Complications; Pregnancy Proteins; Solute Carrier Family 22 Member 5; Tiagabine; Topiramate; Triazines; Valproic Acid; Vigabatrin | 2004 |
Early cyclosporine treatment of incipient toxic epidermal necrolysis induced by concomitant use of lamotrigine and sodium valproate.
Topics: Adult; Anticonvulsants; Cyclosporine; Dermatologic Agents; Drug Therapy, Combination; Epilepsy, Complex Partial; Female; Humans; Lamotrigine; Stevens-Johnson Syndrome; Triazines; Valproic Acid | 2004 |
Antiepileptic drugs inhibit cell growth in the human breast cancer cell line MCF7.
Topics: Anticonvulsants; Breast Neoplasms; Cell Division; Cell Line, Tumor; Drug Screening Assays, Antitumor; Estrogens; Female; Humans; Lamotrigine; Phenobarbital; Phenytoin; Protein Binding; Receptors, Estrogen; Triazines; Valproic Acid | 2004 |
Delirium from valproic acid with lamotrigine.
Topics: Anticonvulsants; Delirium; Drug Interactions; Drug Therapy, Combination; Epilepsy, Complex Partial; Female; Humans; Lamotrigine; Middle Aged; Triazines; Valproic Acid | 2004 |
Serum androgen levels and testicular structure during pubertal maturation in male subjects with epilepsy.
Topics: Adolescent; Adult; Androgens; Androstenedione; Anticonvulsants; Carbamazepine; Child; Epilepsy; Humans; Lamotrigine; Male; Oxcarbazepine; Puberty; Regression Analysis; Sex Hormone-Binding Globulin; Testis; Testosterone; Triazines; Valproic Acid | 2004 |
Lamotrigine-induced seizure aggravation and negative myoclonus in idiopathic rolandic epilepsy.
Topics: Anticonvulsants; Child; Drug Therapy, Combination; Electroencephalography; Electromyography; Epilepsy, Rolandic; Female; Humans; Lamotrigine; Myoclonus; Seizures; Sleep Disorders, Intrinsic; Triazines; Valproic Acid | 2004 |
Anticonvulsants as mood stabilizers and adjuncts to antipsychotics: valproate, lamotrigine, carbamazepine, and oxcarbazepine and actions at voltage-gated sodium channels.
Topics: Affect; Anticonvulsants; Antipsychotic Agents; Bipolar Disorder; Carbamazepine; Drug Therapy, Combination; Humans; Lamotrigine; Oxcarbazepine; Psychotic Disorders; Schizophrenia; Schizophrenic Psychology; Sodium Channel Blockers; Sodium Channels; Treatment Outcome; Triazines; Valproic Acid | 2004 |
Cognitive profile of topiramate as compared with lamotrigine in epilepsy patients on antiepileptic drug polytherapy: relationships to blood serum levels and comedication.
Topics: Adult; Anticonvulsants; Cognition; Drug Therapy, Combination; Epilepsy; Female; Fructose; Humans; Lamotrigine; Language; Male; Memory; Neuropsychological Tests; Retrospective Studies; Topiramate; Triazines; Valproic Acid | 2004 |
Lamotrigine therapy in treatment-resistant menstrually-related rapid cycling bipolar disorder: a case report.
Topics: Adult; Antimanic Agents; Bipolar Disorder; Chronobiology Phenomena; Cyclohexanols; Drug Resistance; Female; Follicular Phase; Humans; Lamotrigine; Menstruation; Thyroxine; Triazines; Valproic Acid; Venlafaxine Hydrochloride | 2004 |
[Anticonvulsant hypersensitivity syndrome].
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Eruptions; Drug Hypersensitivity; Ethosuximide; Fever; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Lymphatic Diseases; Phenobarbital; Phenytoin; Syndrome; Triazines; Valproic Acid | 2004 |
Navigating toward fetal and maternal health: the challenge of treating epilepsy in pregnancy.
Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Carbamazepine; Child; Cohort Studies; Confounding Factors, Epidemiologic; Epilepsy; Female; Humans; Lamotrigine; Maternal Welfare; Practice Patterns, Physicians'; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Registries; Research Design; Risk Factors; Triazines; Valproic Acid | 2004 |
The outcome of initiation of antiepileptic drug monotherapy in primary care: a UK database survey.
Topics: Aged; Anticonvulsants; Carbamazepine; Child, Preschool; Clinical Competence; Epilepsy; Family Practice; Female; Humans; Lamotrigine; Male; Phenytoin; Treatment Outcome; Triazines; Valproic Acid | 2004 |
Australian pregnancy registry of women taking antiepileptic drugs.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Australia; Drug Therapy, Combination; Epilepsy; Female; Humans; Infant, Newborn; Lamotrigine; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Prospective Studies; Registries; Retrospective Studies; Risk Factors; Triazines; Valproic Acid | 2004 |
[Influence of psychotropic drugs on thrombocytes aggregation in patients with epilepsy].
Topics: Adolescent; Adult; Barbiturates; Carbamazepine; Epilepsy; Humans; In Vitro Techniques; Lamotrigine; Middle Aged; Phenobarbital; Phenytoin; Platelet Aggregation; Psychotropic Drugs; Thrombocytopenia; Triazines; Valproic Acid | 2004 |
Video-EEG study in an adult and a child with eyelid myoclonia with absences.
Topics: Adult; Anticonvulsants; Child; Dominance, Cerebral; Drug Therapy, Combination; Electroencephalography; Epilepsies, Myoclonic; Epilepsy, Absence; Epilepsy, Reflex; Evoked Potentials; Female; Frontal Lobe; Humans; Lamotrigine; Male; Myoclonus; Phenytoin; Photic Stimulation; Sunlight; Triazines; Valproic Acid; Video Recording | 2004 |
Effects of combined lamotrigine and valproate on basal and stimulated extracellular amino acids and monoamines in the hippocampus of freely moving rats.
Topics: Animals; Anticonvulsants; Biogenic Monoamines; Brain Chemistry; Drug Interactions; Extracellular Space; Hippocampus; Lamotrigine; Male; Microdialysis; Neurotransmitter Agents; Rats; Rats, Wistar; Triazines; Valproic Acid; Veratridine | 2005 |
Evaluation of the effects of lamotrigine, valproate and carbamazepine in a rodent model of mania.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Bipolar Disorder; Carbamazepine; Central Nervous System Stimulants; Chlordiazepoxide; Dextroamphetamine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation; Drug Interactions; Drug Therapy, Combination; Lamotrigine; Mice; Motor Activity; Pentylenetetrazole; Psychomotor Agitation; Seizures; Triazines; Valproic Acid | 2005 |
Effects of anticonvulsants on human p450c17 (17alpha-hydroxylase/17,20 lyase) and 3beta-hydroxysteroid dehydrogenase type 2.
Topics: 17-Hydroxysteroid Dehydrogenases; Adrenal Cortex Hormones; Androgens; Anticonvulsants; Carbamazepine; Female; Fructose; Humans; Kinetics; Lamotrigine; Microsomes; Mineralocorticoids; Polycystic Ovary Syndrome; Steroid 17-alpha-Hydroxylase; Substrate Specificity; Topiramate; Triazines; Valproic Acid | 2005 |
Lamotrigine-induced rash--worth a rechallenge.
Topics: Anticonvulsants; Epilepsy, Generalized; Exanthema; Humans; Lamotrigine; Retrospective Studies; Risk Factors; Triazines; Valproic Acid | 2005 |
Stevens-Johnson syndrome associated with single high dose of lamotrigine in a patient taking valproate.
Topics: Adult; Anticonvulsants; Drug Interactions; Epilepsy, Tonic-Clonic; Humans; Lamotrigine; Male; Stevens-Johnson Syndrome; Triazines; Valproic Acid | 2005 |
What can we say to women of reproductive age with epilepsy?
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Anticonvulsants; Dose-Response Relationship, Drug; Epilepsy; Female; Humans; Lamotrigine; Nervous System Malformations; Patient Education as Topic; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Risk Assessment; Status Epilepticus; Triazines; Valproic Acid | 2005 |
Risk of Stevens-Johnson syndrome and toxic epidermal necrolysis in new users of antiepileptics.
Topics: Anticonvulsants; Carbamazepine; Causality; Epilepsy; Germany; Humans; Incidence; Inpatients; Lamotrigine; Phenobarbital; Phenytoin; Prohibitins; Registries; Reproducibility of Results; Risk Assessment; Risk Factors; Stevens-Johnson Syndrome; Triazines; Valproic Acid | 2005 |
Images in clinical medicine. Stevens-Johnson syndrome.
Topics: Adult; Anticonvulsants; Drug Synergism; Female; Humans; Lamotrigine; Stevens-Johnson Syndrome; Triazines; Valproic Acid | 2005 |
Telogen effluvium caused by magnesium valproate and lamotrigine.
Topics: Acute Disease; Adolescent; Adult; Alopecia; Anticonvulsants; Epilepsy; Female; Humans; Lamotrigine; Triazines; Valproic Acid | 2005 |
Valproic acid, but not lamotrigine, suppresses seizure-induced c-fos and c-Jun mRNA expression.
Topics: Animals; Anticonvulsants; Behavior, Animal; Brain; Flurothyl; Gene Expression Regulation; In Situ Hybridization; Lamotrigine; Male; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats; Rats, Sprague-Dawley; Reaction Time; RNA, Messenger; Seizures; Triazines; Valproic Acid | 2005 |
Anticonvulsant hypersensitivity syndrome from addition of lamotrigine to divalproex.
Topics: Anticonvulsants; Bipolar Disorder; Drug Hypersensitivity; Drug Therapy, Combination; Exanthema; Female; Humans; Lamotrigine; Middle Aged; Triazines; Valproic Acid | 2005 |
Blood homocysteine, folate and vitamin B-12 concentrations in patients with epilepsy receiving lamotrigine or sodium valproate for initial monotherapy.
Topics: Adult; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Lamotrigine; Male; Middle Aged; Triazines; Valproic Acid; Vitamin B 12 | 2005 |
Potential risks associated with high-dose valproate in pregnancy in psychiatric patients.
Topics: Adult; Antimanic Agents; Bipolar Disorder; Depressive Disorder, Major; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fetal Diseases; Humans; Lamotrigine; Pregnancy; Triazines; Valproic Acid | 2005 |
Lamotrigine add-on to valproate therapy for paediatric bipolar affective disorder.
Topics: Antimanic Agents; Bipolar Disorder; Child; Drug Therapy, Combination; Humans; Lamotrigine; Male; Triazines; Valproic Acid | 2005 |
Outcome measurement, outcome management and monitoring.
Topics: Anticonvulsants; Antipsychotic Agents; Australia; Benzodiazepines; Bipolar Disorder; Carbamazepine; Drug Monitoring; Humans; Lamotrigine; Lithium Carbonate; Olanzapine; Outcome and Process Assessment, Health Care; Surveys and Questionnaires; Treatment Outcome; Triazines; Valproic Acid | 2005 |
Worsening of psychotic symptoms in schizophrenia with addition of lamotrigine: a case report.
Topics: Adult; Antipsychotic Agents; Brain; Clozapine; Drug Therapy, Combination; Female; Humans; Lamotrigine; Lithium Carbonate; Magnetic Resonance Imaging; Psychotic Disorders; Schizophrenia; Severity of Illness Index; Triazines; Valproic Acid | 2005 |
Pharmacokinetic interactions of carbamazepine with some antiepileptic drugs during epilepsy treatment in children and adolescents.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Drug Interactions; Epilepsy; Female; Fructose; Humans; Lamotrigine; Male; Protein Binding; Topiramate; Triazines; Valproic Acid; Vigabatrin | 2005 |
Pregabalin drug interaction studies: lack of effect on the pharmacokinetics of carbamazepine, phenytoin, lamotrigine, and valproate in patients with partial epilepsy.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Drug Interactions; Drug Therapy, Combination; Epilepsies, Partial; Female; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Middle Aged; Phenytoin; Pregabalin; Triazines; Valproic Acid | 2005 |
Lamotrigine associated with exacerbation or de novo myoclonus in idiopathic generalized epilepsies.
Topics: Adult; Anticonvulsants; Brain; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Epilepsies, Myoclonic; Epilepsy; Female; Humans; Lamotrigine; Middle Aged; Myoclonus; Triazines; Valproic Acid | 2005 |
Toxic epidermal necrolysis with combination lamotrigine and valproate in bipolar disorder.
Topics: Adult; Anticonvulsants; Bipolar Disorder; Drug Therapy, Combination; Female; Humans; Lamotrigine; Stevens-Johnson Syndrome; Triazines; Valproic Acid | 2006 |
Interstitial pneumonitis during lamotrigine therapy.
Topics: Anticonvulsants; Drug Therapy, Combination; Female; Humans; Lamotrigine; Lung Diseases, Interstitial; Middle Aged; Triazines; Valproic Acid | 2005 |
[The efficacy of topiramate (topamax) in the treatment of resistant epilepsy in children].
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Resistance; Drug Therapy, Combination; Epilepsy; Female; Fructose; Humans; Infant; Lamotrigine; Male; Topiramate; Treatment Outcome; Triazines; Valproic Acid; Vigabatrin | 2005 |
The use of lamotrigine and other antiepileptic drugs in paediatric patients at a Malaysian hospital.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cost-Benefit Analysis; Drug Therapy, Combination; Drug Utilization; Epilepsy; Female; Humans; Lamotrigine; Malaysia; Male; Medical Records; Practice Patterns, Physicians'; Retrospective Studies; Seizures; Triazines; Valproic Acid | 2005 |
Adjunctive lamotrigine as a possible mania inducer in bipolar patients.
Topics: Adult; Antidepressive Agents; Antipsychotic Agents; Bipolar Disorder; Dibenzothiazepines; Drug Therapy, Combination; Female; Humans; Lamotrigine; Lithium; Male; Quetiapine Fumarate; Triazines; Valproic Acid | 2006 |
Influence of lamotrigine and topiramate on MDR1 expression in difficult-to-treat temporal lobe epilepsy.
Topics: Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain; Carbamazepine; Disease Models, Animal; Drug Resistance; Epilepsy, Temporal Lobe; Fructose; Gene Expression; Genes, MDR; Humans; Immunohistochemistry; Kindling, Neurologic; Lactones; Lamotrigine; Male; Random Allocation; Rats; Rats, Sprague-Dawley; Topiramate; Triazines; Valproic Acid | 2006 |
Epilepsy with myoclonic absences.
Topics: Anticonvulsants; Child; Drug Therapy, Combination; Electroencephalography; Epilepsy, Tonic-Clonic; Female; Humans; Lamotrigine; Mental Disorders; Triazines; Valproic Acid | 2006 |
In vitro characterization of lamotrigine N2-glucuronidation and the lamotrigine-valproic acid interaction.
Topics: Anticonvulsants; Area Under Curve; Cell Line; Drug Interactions; Enzyme Inhibitors; Fluconazole; Glucuronosyltransferase; Humans; In Vitro Techniques; Isoenzymes; Kinetics; Lamotrigine; Microsomes, Liver; Models, Biological; Recombinant Proteins; Sapogenins; Serum Albumin, Bovine; Triazines; Valproic Acid; Zidovudine | 2006 |
Safety and tolerability of mood-stabilising anticonvulsants in the elderly.
Topics: Aged; Aged, 80 and over; Anticonvulsants; Antimanic Agents; Bipolar Disorder; Carbamazepine; Drug Interactions; Humans; Lamotrigine; Middle Aged; Triazines; Valproic Acid | 2006 |
A retrospective analysis of changing from alternative agents to carbamazepine extended-release capsules in bipolar disorder.
Topics: Adolescent; Adult; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Capsules; Carbamazepine; Child; Child, Preschool; Delayed-Action Preparations; Female; Humans; Lamotrigine; Lithium Carbonate; Male; Middle Aged; Olanzapine; Oxcarbazepine; Retrospective Studies; Treatment Outcome; Triazines; Valproic Acid | 2006 |
Atypical antipsychotics related metabolic syndrome in bipolar patients.
Topics: Adolescent; Adult; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Body Mass Index; Carbamazepine; Cross-Sectional Studies; Diagnostic and Statistical Manual of Mental Disorders; Dibenzothiazepines; Female; Humans; Lamotrigine; Lithium Carbonate; Male; Metabolic Syndrome; Middle Aged; Olanzapine; Prevalence; Quetiapine Fumarate; Risperidone; Severity of Illness Index; Triazines; Valproic Acid | 2007 |
[Reintroduction of treatment with lamotrigine in combination with valproate after an initial allergic skin reaction].
Topics: Adult; Anticonvulsants; Drug Eruptions; Drug Therapy, Combination; Epilepsy, Absence; Female; Humans; Lamotrigine; Male; Triazines; Valproic Acid | 2006 |
[Exacerbation of tonicoclonic seizures in a juvenile myoclonic epileptic taking lamotrigine].
Topics: Adult; Anticonvulsants; Electroencephalography; Epilepsy, Tonic-Clonic; Humans; Lamotrigine; Male; Myoclonic Epilepsy, Juvenile; Triazines; Valproic Acid | 2006 |
How to replace lamotrigine with valproate.
Topics: Adolescent; Adult; Anticonvulsants; Cost-Benefit Analysis; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Lamotrigine; Treatment Outcome; Triazines; Valproic Acid | 2006 |
Lamotrigine combined with divalproex or lithium for bipolar disorder: a case series.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Antimanic Agents; Bipolar Disorder; Drug Therapy, Combination; Female; Humans; Lamotrigine; Lithium Compounds; Male; Middle Aged; Retrospective Studies; Treatment Outcome; Triazines; Valproic Acid | 2006 |
Canadian Network for Mood and Anxiety Treatments (CANMAT) guidelines for the management of patients with bipolar disorder: update 2007.
Topics: Acute Disease; Antidepressive Agents; Antipsychotic Agents; Anxiety Disorders; Benzodiazepines; Bipolar Disorder; Canada; Comorbidity; Dibenzothiazepines; Drug Therapy, Combination; Humans; Lamotrigine; Lithium Carbonate; Mood Disorders; Olanzapine; Quetiapine Fumarate; Triazines; Valproic Acid | 2006 |
Role of glutathione in neuroprotective effects of mood stabilizing drugs lithium and valproate.
Topics: Animals; Antimanic Agents; Brain; Carbamazepine; Cell Death; Cell Line, Tumor; Cells, Cultured; Cerebral Cortex; Enzyme Inhibitors; Glutamate-Cysteine Ligase; Glutathione; Humans; Lamotrigine; Lithium; Nerve Degeneration; Neurons; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Triazines; Valproic Acid | 2007 |
A 6-month longitudinal study of bone mineral density with antiepileptic drug monotherapy.
Topics: Adolescent; Adult; Anticonvulsants; Biomarkers; Bone Density; Bone Diseases, Metabolic; Calcitriol; Carbamazepine; Epilepsy; Female; Humans; Lamotrigine; Longitudinal Studies; Male; Middle Aged; Parathyroid Hormone; Triazines; Valproic Acid; Vitamin D | 2007 |
Lamotrigine added to valproate successfully treated a case of ultra-rapid cycling bipolar disorder.
Topics: Adult; Antimanic Agents; Bipolar Disorder; Calcium Channel Blockers; Drug Therapy, Combination; Humans; Lamotrigine; Male; Psychiatric Status Rating Scales; Triazines; Valproic Acid | 2007 |
Translocation-positive acute myeloid leukemia associated with valproic acid therapy.
Topics: Acute Disease; Anticonvulsants; Cell Differentiation; Cell Division; Child, Preschool; Chromosomes, Human, Pair 16; Chromosomes, Human, Pair 8; Clone Cells; Cocarcinogenesis; Drug Therapy, Combination; Epilepsy, Absence; Female; Humans; Isoxazoles; Lamotrigine; Leukemia, Myeloid; Levetiracetam; Neoplastic Stem Cells; Oncogene Proteins, Fusion; Phenobarbital; Piracetam; Translocation, Genetic; Triazines; Valproic Acid; Zonisamide | 2008 |
Myoclonic seizures in a patient with Charcot-Marie-tooth disease.
Topics: Anticonvulsants; Carbamazepine; Charcot-Marie-Tooth Disease; Child; Developmental Disabilities; Drug Therapy, Combination; Epilepsies, Myoclonic; Gene Duplication; Humans; Lamotrigine; Male; Myelin Proteins; Triazines; Valproic Acid | 2007 |
An interaction study between the new antiepileptic and CNS drug carisbamate (RWJ-333369) and lamotrigine and valproic acid.
Topics: Anticonvulsants; Area Under Curve; Carbamates; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Humans; Lamotrigine; Triazines; Valproic Acid | 2007 |
Adverse events caused by drug interactions involving glucuronoconjugates of zidovudine, valproic acid and lamotrigine, and analysis of how such potential events are discussed in package inserts of Japan, UK and USA.
Topics: Area Under Curve; Communication; Disclosure; Drug Combinations; Drug Interactions; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Glucuronates; Half-Life; Humans; Japan; Lamotrigine; Triazines; United Kingdom; United States; Valproic Acid; Zidovudine | 2007 |
Stevens-Johnson syndrome due to concomitant use of lamotrigine and valproic acid.
Topics: Adult; Anticonvulsants; Carbamazepine; Drug Therapy, Combination; Epilepsy; Female; Humans; Lamotrigine; Stevens-Johnson Syndrome; Triazines; Valproic Acid | 2007 |
Prophylactic treatment response in bipolar disorder: results of a naturalistic observation study.
Topics: Adult; Aged; Aged, 80 and over; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Carbamazepine; Female; Humans; Lamotrigine; Lithium Carbonate; Male; Middle Aged; Observation; Observer Variation; Olanzapine; Treatment Outcome; Triazines; Valproic Acid | 2007 |
Juvenile myoclonic epilepsy: a benign disorder? Personality traits and psychiatric symptoms.
Topics: Adolescent; Adult; Anticonvulsants; Child; Ethosuximide; Female; Fructose; Humans; Lamotrigine; Levetiracetam; Male; Mental Disorders; Myoclonic Epilepsy, Juvenile; Personality; Personality Tests; Piracetam; Psychiatric Status Rating Scales; Surveys and Questionnaires; Topiramate; Triazines; Valproic Acid | 2007 |
Lamotrigine in children and adolescents: the impact of age on its serum concentrations and on the extent of drug interactions.
Topics: Adolescent; Adult; Age Factors; Anticonvulsants; Antidepressive Agents; Benzodiazepines; Child; Child, Preschool; Contraceptives, Oral, Combined; Drug Interactions; Drug Therapy, Combination; Ethinyl Estradiol; Female; Fluoxetine; Humans; Lamotrigine; Male; Models, Biological; Triazines; Valproic Acid | 2007 |
Lamotrigine is neuroprotective in the energy deficiency model of MPTP intoxicated mice.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Anticonvulsants; Apoptosis; Corpus Striatum; Dopamine; Dopamine Agents; Energy Metabolism; Fructose; Lamotrigine; Male; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Neurotoxins; Topiramate; Triazines; Valproic Acid | 2007 |
Metabolic and hormonal disturbances in women with epilepsy on antiepileptic drug monotherapy.
Topics: Adolescent; Adult; Anticonvulsants; Blood Glucose; Body Mass Index; Carbamazepine; Comorbidity; Epilepsy; Female; Humans; Insulin; Insulin Resistance; Lamotrigine; Leptin; Lipids; Metabolic Syndrome; Obesity; Risk Factors; Sex Factors; Triazines; Valproic Acid | 2007 |
Robust isocratic high performance liquid chromatographic method for simultaneous determination of seven antiepileptic drugs including lamotrigine, oxcarbazepine and zonisamide in serum after solid-phase extraction.
Topics: Analysis of Variance; Animals; Anticonvulsants; Carbamazepine; Cattle; Chromatography, High Pressure Liquid; Drug Monitoring; Ethosuximide; Humans; Isoxazoles; Lamotrigine; Oxcarbazepine; Phenobarbital; Phenytoin; Primidone; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Solid Phase Extraction; Solutions; Specimen Handling; Spectrophotometry, Ultraviolet; Temperature; Triazines; Valproic Acid; Zonisamide | 2007 |
Addition of lamotrigine to valproic acid: a successful outcome in a case of rapid-cycling bipolar affective disorder.
Topics: Adult; Antimanic Agents; Bipolar Disorder; Depressive Disorder, Major; Female; Humans; Lamotrigine; Lithium Carbonate; Psychiatric Status Rating Scales; Triazines; Valproic Acid | 2007 |
Old versus new antiepileptic drugs: the SANAD study.
Topics: Adult; Anticonvulsants; Carbamazepine; Epilepsy; Humans; Lamotrigine; Triazines; Valproic Acid | 2007 |
Conversion to lamotrigine monotherapy from valproate monotherapy in older adolescent patients with epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Dose-Response Relationship, Drug; Epilepsy; Female; Humans; Lamotrigine; Male; Triazines; Valproic Acid | 2007 |
Unlike lithium, anticonvulsants and antidepressants do not alter rat brain myo-inositol.
Topics: Animals; Anticonvulsants; Antidepressive Agents; Antimanic Agents; Brain Chemistry; Carbamazepine; Cerebral Cortex; Hippocampus; Inositol; Lamotrigine; Lithium Carbonate; Magnetic Resonance Spectroscopy; Male; Rats; Rats, Sprague-Dawley; Triazines; Valproic Acid | 2007 |
Seizure-freedom with combination therapy in localization-related epilepsy.
Topics: Adult; Anticonvulsants; Brain; Carbamazepine; Drug Therapy, Combination; Female; Frontal Lobe; Fructose; Humans; Lamotrigine; Levetiracetam; Male; Nipecotic Acids; Occipital Lobe; Oxcarbazepine; Parietal Lobe; Piracetam; Seizures; Temporal Lobe; Tiagabine; Topiramate; Treatment Outcome; Triazines; Valproic Acid | 2008 |
Which patients become seizure free with antiepileptic drugs? An observational study in 821 patients with epilepsy.
Topics: Adult; Anticonvulsants; Carbamazepine; Cohort Studies; Drug Resistance; Drug Therapy, Combination; Epilepsy; Female; Fructose; Humans; Lamotrigine; Male; Middle Aged; Prognosis; Retrospective Studies; Secondary Prevention; Topiramate; Treatment Outcome; Triazines; Valproic Acid | 2008 |
Aseptic meningitis associated with lamotrigine: report of two cases.
Topics: Acquired Immunodeficiency Syndrome; Adult; Anticonvulsants; Blood; Blood Chemical Analysis; Cerebrospinal Fluid; Diagnosis, Differential; Female; Fever; Humans; Lamotrigine; Male; Meningitis, Aseptic; Meningitis, Bacterial; Meningitis, Viral; Phenobarbital; Triazines; Valproic Acid | 2007 |
Lamotrigine serum concentrations under valproate comedication: "contraindication" or "safe combination"? A case report.
Topics: Adult; Anticonvulsants; Antimanic Agents; Chromatography, High Pressure Liquid; Contraindications; Drug Combinations; Drug Interactions; Epilepsy, Tonic-Clonic; Humans; Lamotrigine; Male; Mental Disorders; Neurocognitive Disorders; Triazines; Valproic Acid | 2007 |
Comments on "Addition of lamotrigine to valproic acid: a successful outcome in a case of rapid-cycling bipolar affective disorder".
Topics: Anticonvulsants; Antipsychotic Agents; Bipolar Disorder; Drug Therapy, Combination; Humans; Lamotrigine; Lithium Compounds; Treatment Outcome; Triazines; Valproic Acid | 2008 |
Lamotrigine and the risk of fulminant hepatic failure.
Topics: Anticonvulsants; Cytomegalovirus Infections; Female; Humans; Lamotrigine; Liver Failure, Acute; Risk Factors; Triazines; Valproic Acid | 2007 |
Lamotrigine and the risk of fulminant hepatic failure.
Topics: Anticonvulsants; Cytomegalovirus Infections; Female; Humans; Lamotrigine; Liver Failure, Acute; Risk Factors; Triazines; Valproic Acid | 2008 |
Quetiapine and classical mood stabilizers in the long-term treatment of Bipolar Disorder: a 4-year follow-up naturalistic study.
Topics: Anticonvulsants; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Dibenzothiazepines; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Lamotrigine; Lithium Carbonate; Longitudinal Studies; Male; Middle Aged; Psychiatric Status Rating Scales; Quetiapine Fumarate; Triazines; Valproic Acid | 2008 |
Simultaneous toxicities in a child on multiple anticonvulsants.
Topics: Anticonvulsants; Bone Marrow; Bone Marrow Diseases; Chemical and Drug Induced Liver Injury; Child, Preschool; Drug Synergism; Drug Therapy, Combination; Epilepsy; Female; Humans; Lamotrigine; Liver; Liver Diseases; Lorazepam; Parainfluenza Virus 3, Human; Paramyxoviridae Infections; Phenytoin; Status Epilepticus; Triazines; Valproic Acid | 2008 |
Treatment of newly diagnosed epilepsies: the shortcomings of SANAD.
Topics: Anticonvulsants; Carbamazepine; Child; Epilepsy; Follow-Up Studies; Humans; Lamotrigine; Randomized Controlled Trials as Topic; Treatment Outcome; Triazines; Valproic Acid | 2008 |
[Secondary delirium due to the use of lamotrigine with abrupt increase valproic acid's dose].
Topics: Adult; Anticonvulsants; Bipolar Disorder; Delirium; Drug Interactions; Drug Therapy, Combination; Humans; Lamotrigine; Male; Triazines; Valproic Acid | 2008 |
Hallucinations during lamotrigine treatment.
Topics: Adolescent; Amitriptyline; Anticonvulsants; Antidepressive Agents, Tricyclic; Erythema Infectiosum; Female; Hallucinations; Humans; Lamotrigine; Triazines; Valproic Acid | 2008 |
Bone health in young women with epilepsy after one year of antiepileptic drug monotherapy.
Topics: Adolescent; Adult; Alkaline Phosphatase; Anticonvulsants; Biomarkers; Bone Density; Bone Diseases, Metabolic; Bone Remodeling; Calcium, Dietary; Carbamazepine; Collagen Type I; Epilepsy; Female; Femur; Humans; Lamotrigine; Life Style; Lumbar Vertebrae; Minerals; Parathyroid Hormone; Peptides; Phenytoin; Surveys and Questionnaires; Triazines; Valproic Acid; Vitamin D | 2008 |
Estimating the effects of co-medications on plasma olanzapine concentrations by using a mixed model.
Topics: Adult; Algorithms; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Dose-Response Relationship, Drug; Drug Interactions; Drug Monitoring; Female; Humans; Lamotrigine; Linear Models; Male; Middle Aged; Olanzapine; Regression Analysis; Smoking; Triazines; Valproic Acid | 2008 |
States of serum leptin and insulin in children with epilepsy: risk predictors of weight gain.
Topics: Adolescent; Age Factors; Anticonvulsants; Body Mass Index; Carbamazepine; Case-Control Studies; Child; Epilepsy; Female; Humans; Hyperinsulinism; Insulin; Lamotrigine; Leptin; Lipids; Male; Predictive Value of Tests; Risk Assessment; Sex Factors; Triazines; Valproic Acid; Weight Gain | 2009 |
Lamotrigine might potentiate valproic acid-induced hyperammonemic encephalopathy.
Topics: Aged; Anticonvulsants; Drug Synergism; Female; Humans; Hyperammonemia; Lamotrigine; Neurotoxicity Syndromes; Triazines; Valproic Acid | 2008 |
Antiepileptic drug utilization in children from 1997-2005--a study from the Netherlands.
Topics: Anticonvulsants; Carbamazepine; Child; Databases, Factual; Drug Utilization; Epilepsy; Female; Humans; Incidence; Lamotrigine; Male; Netherlands; Practice Guidelines as Topic; Prevalence; Retrospective Studies; Triazines; Valproic Acid | 2008 |
Isobolographic characterization of interactions of retigabine with carbamazepine, lamotrigine, and valproate in the mouse maximal electroshock-induced seizure model.
Topics: Animals; Anticonvulsants; Avoidance Learning; Behavior, Animal; Brain; Carbamates; Carbamazepine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Electroshock; Injections, Intraperitoneal; Lamotrigine; Male; Memory; Mice; Motor Activity; Muscle Strength; Phenylenediamines; Psychomotor Performance; Seizures; Triazines; Valproic Acid | 2009 |
Association of lamotrigine and valproate in refractory epilepsies of children and adolescents.
Topics: Adolescent; Age Distribution; Anticonvulsants; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Female; Humans; Lamotrigine; Male; Retrospective Studies; Seizures; Sex Distribution; Treatment Outcome; Triazines; Valproic Acid; Young Adult | 2008 |
Patterns of antiepileptic drug overdose differ between men and women: admissions to the Edinburgh Poisons Unit, 2000-2007.
Topics: Adult; Anticonvulsants; Carbamazepine; Drug Overdose; Female; Humans; Lamotrigine; Male; Middle Aged; Phenytoin; Psychotic Disorders; Retrospective Studies; Sex Distribution; Suicide, Attempted; Triazines; Valproic Acid; Young Adult | 2009 |
Lamotrigine-valproic acid combination therapy for medically refractory epilepsy.
Topics: Adolescent; Adult; Age of Onset; Anticonvulsants; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsies, Partial; Epilepsy, Generalized; Female; Follow-Up Studies; Humans; Infant; Lamotrigine; Male; Retrospective Studies; Treatment Outcome; Triazines; Valproic Acid | 2009 |
A case with Stevens Johnson syndrome triggered by combination of clobazam, lamotrigine, and valproic acid treatment.
Topics: Anticonvulsants; Benzodiazepines; Child, Preschool; Clobazam; Drug Therapy, Combination; Follow-Up Studies; Humans; Lamotrigine; Male; Prednisolone; Risk Assessment; Seizures; Stevens-Johnson Syndrome; Treatment Outcome; Triazines; Valproic Acid | 2009 |
Improvement of obsessive-compulsive disorder with divalproex and lamotrigine in two patients with bipolar II disorder.
Topics: Adult; Anticonvulsants; Bipolar Disorder; Female; Humans; Lamotrigine; Male; Obsessive-Compulsive Disorder; Triazines; Valproic Acid | 2009 |
Valproate and lamotrigine level variation with menstrual cycle phase and oral contraceptive use.
Topics: Adolescent; Adult; Anticonvulsants; Body Mass Index; Contraceptives, Oral, Combined; Drug Interactions; Epilepsy; Female; Follicular Phase; Humans; Lamotrigine; Luteal Phase; Menstrual Cycle; Middle Aged; Triazines; Valproic Acid; Young Adult | 2009 |
Changing trends in antiepileptic drug prescribing in girls of child-bearing potential.
Topics: Abnormalities, Drug-Induced; Adolescent; Anticonvulsants; Carbamazepine; Child; Contraceptive Agents; Drug Interactions; Epilepsy; Female; Humans; Lamotrigine; Practice Patterns, Physicians'; Pregnancy; Triazines; Valproic Acid | 2009 |
[When a seizure occurs...].
Topics: Adult; Anticonvulsants; Carbamazepine; Drug Therapy, Combination; Epilepsy; Female; Fructose; Humans; Lamotrigine; Levetiracetam; Piracetam; Topiramate; Treatment Outcome; Triazines; Valproic Acid | 2009 |
Prolyl oligopeptidase binds to GAP-43 and functions without its peptidase activity.
Topics: Animals; Antimanic Agents; Carbamazepine; Cell Culture Techniques; DNA, Complementary; GAP-43 Protein; Growth Cones; Humans; Indoles; Lamotrigine; Lithium Chloride; Mice; Mice, Knockout; Phosphatidylinositols; Prolyl Oligopeptidases; Rats; Serine Endopeptidases; Thiazolidines; Triazines; Valproic Acid | 2009 |
Cognitive function at 3 years of age after fetal exposure to antiepileptic drugs.
Topics: Adult; Anticonvulsants; Carbamazepine; Child, Preschool; Cognition; Developmental Disabilities; Dose-Response Relationship, Drug; Epilepsy; Female; Humans; Intelligence; Intelligence Tests; Lamotrigine; Neuropsychological Tests; Phenytoin; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Prospective Studies; Regression Analysis; Triazines; Valproic Acid | 2009 |
Life-threatening organ failure after lamotrigine therapy.
Topics: Anticonvulsants; Child; Contraindications; Drug Therapy, Combination; Exanthema; Female; Fever; Humans; Lamotrigine; Multiple Organ Failure; Rhabdomyolysis; Seizures; Treatment Outcome; Triazines; Valproic Acid | 2009 |
Variation in glucuronidation of lamotrigine in human liver microsomes.
Topics: Adolescent; Adult; Age Factors; Aged; Anticonvulsants; Child; Child, Preschool; Chromatography, Liquid; Glucuronides; Glucuronosyltransferase; Humans; Lamotrigine; Mass Spectrometry; Microsomes, Liver; Middle Aged; Triazines; Valproic Acid; Young Adult | 2009 |
Mood stabilizers increase prepulse inhibition in DBA/2NCrl mice.
Topics: Acoustic Stimulation; Animals; Anticonvulsants; Antimanic Agents; Carbamazepine; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Fructose; Injections, Intraperitoneal; Lamotrigine; Lithium Chloride; Male; Mice; Mice, Inbred DBA; Reflex, Startle; Topiramate; Triazines; Valproic Acid | 2009 |
Efficacy of anti-epileptic drugs in patients with gliomas and seizures.
Topics: Adult; Anticonvulsants; Brain Neoplasms; Carbamazepine; Drug Therapy, Combination; Female; Follow-Up Studies; Glioma; Humans; Kaplan-Meier Estimate; Lamotrigine; Levetiracetam; Male; Middle Aged; Neoplasm Staging; Piracetam; Seizures; Time Factors; Treatment Outcome; Triazines; Valproic Acid | 2009 |
Epilepsy in Angelman syndrome: a questionnaire-based assessment of the natural history and current treatment options.
Topics: Adolescent; Adult; Angelman Syndrome; Anticonvulsants; Child; Child, Preschool; Clonazepam; Comorbidity; Drug Administration Schedule; Drug Resistance; Epilepsy; Epilepsy, Generalized; Female; Humans; Infant; Lamotrigine; Levetiracetam; Male; Middle Aged; Piracetam; Surveys and Questionnaires; Syndrome; Treatment Outcome; Triazines; Vagus Nerve Stimulation; Valproic Acid | 2009 |
Maintenance treatment received by patients with bipolar I and II disorders--a naturalistic prospective study.
Topics: Adult; Anticonvulsants; Antimanic Agents; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Bipolar Disorder; Carbamazepine; Cohort Studies; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Lamotrigine; Lithium Carbonate; Long-Term Care; Male; Middle Aged; Olanzapine; Oxcarbazepine; Piperazines; Prospective Studies; Quinolones; Risperidone; Triazines; Valproic Acid | 2010 |
Clinical and neurocognitive predictors of functional outcome in bipolar euthymic patients: a long-term, follow-up study.
Topics: Adult; Affect; Anticonvulsants; Antimanic Agents; Bipolar Disorder; Cognition Disorders; Female; Follow-Up Studies; Humans; Lamotrigine; Lithium Carbonate; Male; Mental Recall; Middle Aged; Neuropsychological Tests; Prognosis; Psychometrics; Social Adjustment; Treatment Outcome; Triazines; Valproic Acid | 2010 |
Ring chromosome 20 syndrome: a link between epilepsy onset and neuropsychological impairment in three children.
Topics: Adult; Age of Onset; Anticonvulsants; Child; Chromosomes, Human, Pair 20; Cognition Disorders; Comorbidity; Drug Resistance; Drug Therapy, Combination; Epilepsy; Female; Humans; Intellectual Disability; Lamotrigine; Neuropsychological Tests; Ring Chromosomes; Syndrome; Triazines; Valproic Acid | 2009 |
Treatment-emergent mania/hypomania during antidepressant monotherapy in patients with rapid cycling bipolar disorder.
Topics: Adult; Affect; Anticonvulsants; Antidepressive Agents, Second-Generation; Antimanic Agents; Bipolar Disorder; Comorbidity; Double-Blind Method; Drug Therapy, Combination; Female; Fluoxetine; Humans; Lamotrigine; Lithium Carbonate; Male; Middle Aged; Randomized Controlled Trials as Topic; Recurrence; Risk Factors; Selective Serotonin Reuptake Inhibitors; Substance-Related Disorders; Triazines; Valproic Acid | 2008 |
Use of a new antiepileptic drug or an old one as first drug for treatment of absence epilepsy.
Topics: Anticonvulsants; Drug Monitoring; Epilepsy, Absence; Ethosuximide; Humans; Lamotrigine; Treatment Outcome; Triazines; Valproic Acid | 2009 |
Chronic antiepileptic monotherapy, bone metabolism, and body composition in non-institutionalized children.
Topics: Anthropometry; Anticonvulsants; Body Composition; Body Height; Body Mass Index; Body Weight; Carbamazepine; Child; Drug Administration Schedule; Drug Therapy; Epilepsy; Female; Fractures, Bone; Humans; Lamotrigine; Male; Oxcarbazepine; Prevalence; Thiazines; Triazines; Valproic Acid | 2010 |
Multiple organ dysfunction syndrome: infection or hypersensitivity reaction?
Topics: Anticonvulsants; Child; Drug Hypersensitivity; Drug Therapy, Combination; Humans; Hypersensitivity, Delayed; Lamotrigine; Male; Multiple Organ Failure; Triazines; Valproic Acid | 2010 |
A prospective study of cognitive fluency and originality in children exposed in utero to carbamazepine, lamotrigine, or valproate monotherapy.
Topics: Analysis of Variance; Anticonvulsants; Carbamazepine; Child, Preschool; Cognition; Creativity; Epilepsy; Female; Humans; Intelligence Tests; Lamotrigine; Male; Neuropsychological Tests; Patient Selection; Pregnancy; Prenatal Exposure Delayed Effects; Prospective Studies; Regression Analysis; Triazines; Valproic Acid | 2009 |
Valproic acid: long-term effects on children exposed in utero.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Cohort Studies; Contraindications; Dose-Response Relationship, Drug; Epilepsy; Female; Fructose; Humans; Intelligence; Lamotrigine; Language Development Disorders; Phenytoin; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Prenatal Exposure Delayed Effects; Psychomotor Disorders; Topiramate; Triazines; Valproic Acid | 2009 |
Adverse effects of carbamazepine, phenytoin, valproate and lamotrigine monotherapy in epileptic adult Chinese patients.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; China; Drug Eruptions; Epilepsy; Female; Humans; Lamotrigine; Male; Middle Aged; Patient Acceptance of Health Care; Phenytoin; Survival Analysis; Treatment Failure; Triazines; Valproic Acid; Young Adult | 2010 |
The World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for the Biological Treatment of Bipolar Disorders: Update 2010 on the treatment of acute bipolar depression.
Topics: Adolescent; Adult; Antidepressive Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Carbamazepine; Child; Dibenzothiazepines; Electroconvulsive Therapy; Humans; Lamotrigine; Lithium Compounds; Olanzapine; Psychiatric Status Rating Scales; Psychotherapy; Quetiapine Fumarate; Triazines; Valproic Acid | 2010 |
Long-term efficacy of valproate versus lamotrigine in treatment of idiopathic generalized epilepsies in children and adolescents.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Epilepsy; Female; Humans; Lamotrigine; Male; Triazines; Valproic Acid | 2010 |
Ethosuximide in childhood absence epilepsy--older and better.
Topics: Anticonvulsants; Child; Diagnosis, Differential; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Ethosuximide; Humans; Lamotrigine; Triazines; Valproic Acid | 2010 |
Infection or idiosyncratic reaction to antiepileptic drugs?
Topics: Adult; Anticonvulsants; Antipsychotic Agents; Bipolar Disorder; Clozapine; Diagnosis, Differential; Drug Therapy, Combination; Humans; Lamotrigine; Male; Pericarditis; Respiratory Insufficiency; Systemic Inflammatory Response Syndrome; Triazines; Valproic Acid | 2010 |
Antiepileptic drugs modify power of high EEG frequencies and their neural generators.
Topics: Adolescent; Adult; Anticonvulsants; Brain Waves; Carbamazepine; Electroencephalography; Epilepsy; Female; Humans; Ion Channels; Lamotrigine; Male; Neurons; Triazines; Valproic Acid; Young Adult | 2010 |
An older drug for childhood absence epilepsy.
Topics: Anticonvulsants; Child; Electroencephalography; Epilepsy, Absence; Ethosuximide; Humans; Lamotrigine; Randomized Controlled Trials as Topic; Treatment Outcome; Triazines; Valproic Acid | 2010 |
Cost effectiveness of adjunctive quetiapine fumarate extended-release tablets with mood stabilizers in the maintenance treatment of bipolar I disorder.
Topics: Absenteeism; Antimanic Agents; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Bipolar Disorder; Cost-Benefit Analysis; Delayed-Action Preparations; Dibenzothiazepines; Drug Therapy, Combination; Fees, Pharmaceutical; Health Care Costs; Hospital Charges; Humans; Lamotrigine; Lithium Compounds; Markov Chains; Models, Economic; Olanzapine; Piperazines; Quality-Adjusted Life Years; Quetiapine Fumarate; Quinolones; Risk; Tablets; Triazines; United States; Valproic Acid | 2010 |
Absence epilepsy and periventricular nodular heterotopia.
Topics: Anticonvulsants; Child, Preschool; Drug Therapy, Combination; Electroencephalography; Epilepsy, Absence; Female; Humans; Lamotrigine; Magnetic Resonance Imaging; Periventricular Nodular Heterotopia; Triazines; Valproic Acid | 2010 |
Quality of life and treatment satisfaction in Spanish epilepsy patients on monotherapy with lamotrigine or valproic acid.
Topics: Adult; Anticonvulsants; Epilepsy; Female; Humans; Lamotrigine; Male; Patient Satisfaction; Quality of Life; Spain; Surveys and Questionnaires; Triazines; Valproic Acid | 2010 |
Effects of AEDs on biomarkers in people with epilepsy: CRP, HbA1c and eGFR.
Topics: Adult; Aged; Aged, 80 and over; Anticonvulsants; Biomarkers; C-Reactive Protein; Epilepsy; Female; Glomerular Filtration Rate; Glycated Hemoglobin; Humans; Lamotrigine; Male; Middle Aged; Triazines; Valproic Acid; Young Adult | 2010 |
Presence of epileptiform discharges on initial EEGs are associated with failure of retention on first antiepileptic drug in newly diagnosed cryptogenic partial epilepsy: a 2-year observational study.
Topics: Adolescent; Adult; Anticonvulsants; Brain; Carbamazepine; Electroencephalography; Epilepsy, Complex Partial; Female; Fructose; Humans; Kaplan-Meier Estimate; Lamotrigine; Male; Middle Aged; Phenytoin; Retrospective Studies; Topiramate; Treatment Outcome; Triazines; Valproic Acid; Young Adult | 2010 |
Is lamotrigine a significant human teratogen? Observations from the Australian Pregnancy Register.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Australia; Congenital Abnormalities; Dose-Response Relationship, Drug; Epilepsy; Female; Humans; Incidence; Lamotrigine; Logistic Models; Odds Ratio; Pregnancy; Pregnancy Complications; Registries; Teratogens; Triazines; Valproic Acid | 2010 |
Age and comedications influence levetiracetam pharmacokinetics in children.
Topics: Adolescent; Age Factors; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Infant; Lamotrigine; Levetiracetam; Male; Metabolic Clearance Rate; Oxcarbazepine; Phenytoin; Piracetam; Retrospective Studies; Triazines; Valproic Acid | 2010 |
Cross-reactivity of skin rashes with current antiepileptic drugs in Chinese population.
Topics: Adolescent; Adult; Aged; Amines; Anticonvulsants; Carbamazepine; Chi-Square Distribution; Child; China; Clonazepam; Cyclohexanecarboxylic Acids; Exanthema; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Levetiracetam; Male; Medicine, Chinese Traditional; Middle Aged; Phenobarbital; Phenytoin; Piracetam; Retrospective Studies; Topiramate; Triazines; Valproic Acid; Young Adult | 2010 |
Migraine preventive drugs differentially affect cortical spreading depression in rat.
Topics: Animals; Anticonvulsants; Cortical Spreading Depression; Lamotrigine; Male; Migraine Disorders; Rats; Rats, Sprague-Dawley; Riboflavin; Treatment Outcome; Triazines; Valproic Acid | 2011 |
Use of mood stabilizers for hospitalized psychotic and bipolar disorder patients.
Topics: Anticonvulsants; Antidepressive Agents; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Drug Therapy, Combination; Female; Hospitalization; Humans; Lamotrigine; Lithium Compounds; Male; Psychiatric Status Rating Scales; Psychotic Disorders; Psychotropic Drugs; Schizophrenia; Treatment Outcome; Triazines; Valproic Acid | 2011 |
Unilateral continuous subclinical paroxysmal activity: an unusual finding in a patient with recurrent absence status.
Topics: Adult; Anticonvulsants; Brain; Carbamazepine; Diagnosis, Differential; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy, Tonic-Clonic; Female; Follow-Up Studies; Fructose; Humans; Lamotrigine; Phenobarbital; Secondary Prevention; Status Epilepticus; Topiramate; Treatment Outcome; Triazines; Valproic Acid; Weight Gain | 2010 |
Effects of breastfeeding in children of women taking antiepileptic drugs.
Topics: Adult; Anticonvulsants; Breast Feeding; Carbamazepine; Child, Preschool; Cognition; Epilepsy; Female; Humans; Infant; Infant, Newborn; Intelligence; Intelligence Tests; Lamotrigine; Linear Models; Pregnancy; Prenatal Exposure Delayed Effects; Prospective Studies; Time; Triazines; Valproic Acid | 2010 |
The effect of lamotrigine on valproic acid concentrations.
Topics: Adolescent; Child; Drug Interactions; Drug Synergism; Drug Therapy, Combination; Epilepsy; Female; Humans; Lamotrigine; Male; Retrospective Studies; Triazines; Valproic Acid; Young Adult | 2011 |
Effect of valproate, lamotrigine and levetiracetam on excitability and firing properties of CA1 neurons in rat brain slices.
Topics: Action Potentials; Animals; Bicuculline; CA1 Region, Hippocampal; Female; In Vitro Techniques; Lamotrigine; Levetiracetam; Male; Neurons; Piracetam; Rats; Rats, Sprague-Dawley; Triazines; Valproic Acid | 2011 |
Valproate treatment after liver transplant in a patient with Lennox-Gastaut syndrome.
Topics: Anticonvulsants; Chemical and Drug Induced Liver Injury; Electroencephalography; Female; Fructose; Humans; Immunosuppressive Agents; Intellectual Disability; Lamotrigine; Lennox Gastaut Syndrome; Liver Function Tests; Liver Transplantation; Phenobarbital; Seizures; Spasms, Infantile; Topiramate; Triazines; Valproic Acid; Young Adult | 2011 |
Neurodevelopment of children exposed in utero to lamotrigine, sodium valproate and carbamazepine.
Topics: Anticonvulsants; Carbamazepine; Case-Control Studies; Child, Preschool; Developmental Disabilities; Epilepsy; Female; Humans; Infant; Infant, Newborn; Lamotrigine; Male; Maternal-Fetal Exchange; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Triazines; Valproic Acid | 2011 |
Effects of antiepileptic drugs on GABA release from rat and human neocortical synaptosomes.
Topics: Adolescent; Adult; Aged; Amines; Animals; Anticonvulsants; Calcium; Carbamazepine; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Female; GABA Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant; Lamotrigine; Levetiracetam; Male; Middle Aged; Neocortex; Nipecotic Acids; Oximes; Phenytoin; Piracetam; Potassium; Pregabalin; Rats; Rats, Wistar; Synaptosomes; Tetanus Toxin; Tetrodotoxin; Triazines; Valproic Acid; Veratridine; Young Adult | 2011 |
Thyroid status in a large cohort of patients with mental retardation: the TOP-R (Thyroid Origin of Psychomotor Retardation) study.
Topics: Adult; Aged; Anticonvulsants; Carbamazepine; Cohort Studies; Cross-Sectional Studies; Drug Therapy, Combination; Female; Humans; Hyperthyroidism; Hypothyroidism; Intellectual Disability; Lamotrigine; Linear Models; Male; Middle Aged; Netherlands; Phenobarbital; Phenytoin; Prevalence; Thyroid Gland; Thyrotropin; Thyroxine; Triazines; Triiodothyronine; Valproic Acid | 2011 |
The relationship between UGT1A4 polymorphism and serum concentration of lamotrigine in patients with epilepsy.
Topics: Adult; Amino Acid Substitution; Anticonvulsants; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Interactions; Epilepsy; Female; Gene Frequency; Genotype; Glucuronosyltransferase; Humans; Inactivation, Metabolic; Lamotrigine; Male; Polymorphism, Single Nucleotide; Smoking; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Triazines; Turkey; Valproic Acid | 2011 |
Final results from 18 years of the International Lamotrigine Pregnancy Registry.
Topics: Abnormalities, Drug-Induced; Animals; Anticonvulsants; Female; Humans; Infant; Lamotrigine; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Pregnancy Trimesters; Registries; Teratogens; Triazines; Valproic Acid | 2011 |
Worsening of negative myoclonus by lamotrigine in a case of idiopathic focal epilepsy of children with long-term follow-up.
Topics: Anticonvulsants; Child, Preschool; Drug Therapy, Combination; Electroencephalography; Epilepsies, Myoclonic; Humans; Lamotrigine; Male; Triazines; Valproic Acid | 2012 |
Dose-dependent risk of malformations with antiepileptic drugs: an analysis of data from the EURAP epilepsy and pregnancy registry.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Epilepsy; Female; Humans; Infant; Infant, Newborn; Lamotrigine; Male; Phenobarbital; Pregnancy; Prenatal Exposure Delayed Effects; Prevalence; Prospective Studies; Registries; Triazines; Valproic Acid | 2011 |
Clinical and pharmacy utilization outcomes with brand to generic antiepileptic switches in patients with epilepsy.
Topics: Anticonvulsants; Drug Substitution; Drugs, Generic; Emergency Service, Hospital; Epilepsy; Female; Hospitalization; Humans; Lamotrigine; Male; Middle Aged; Phenytoin; Proportional Hazards Models; Regression Analysis; Retrospective Studies; Treatment Outcome; Triazines; Valproic Acid | 2011 |
Haematological side effects of antiepileptic drug treatment in patients with epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Blood Platelets; Carbamazepine; Cross-Sectional Studies; Epilepsy; Female; Humans; Lamotrigine; Leukocytes; Levetiracetam; Male; Middle Aged; Piracetam; Platelet Count; Triazines; Valproic Acid | 2011 |
Long-term effectiveness of ethosuximide, valproic acid, and lamotrigine in childhood absence epilepsy.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Electroencephalography; Epilepsy, Absence; Ethosuximide; Female; Follow-Up Studies; Humans; Lamotrigine; Male; Retrospective Studies; Treatment Outcome; Triazines; Valproic Acid; Young Adult | 2012 |
[Epilepsy in elderly].
Topics: Aged; Aged, 80 and over; Aging; Anticonvulsants; Carbamazepine; Electroencephalography; Epilepsies, Partial; Epilepsy; Female; Fructose; Humans; Lamotrigine; Magnetic Resonance Imaging; Male; Middle Aged; Patient Compliance; Phenobarbital; Phenytoin; Topiramate; Triazines; Valproic Acid | 2011 |
Vulnerability of an epileptic case to psychosis: sodium valproate with lamotrigine, forced normalization, postictal psychosis or all?
Topics: Adult; Age of Onset; Anticonvulsants; Child; Drug Therapy, Combination; Electroencephalography; Epilepsy; Humans; Lamotrigine; Male; Psychotic Disorders; Triazines; Valproic Acid | 2012 |
Comparative efficacy of combination drug therapy in refractory epilepsy.
Topics: Anticonvulsants; Developmental Disabilities; Drug Therapy, Combination; Epilepsy; Female; Humans; Lamotrigine; Male; Middle Aged; Retrospective Studies; Treatment Outcome; Triazines; Valproic Acid | 2012 |
[Lamotrigine add-on therapy for childhood-onset refractory epilepsy: comparison of the efficacy between 3 months and 6 months after initiation].
Topics: Adolescent; Adult; Age of Onset; Anticonvulsants; Child; Child, Preschool; Drug Therapy, Combination; Electroencephalography; Epilepsy; Female; Humans; Lamotrigine; Male; Quality of Life; Time Factors; Triazines; Valproic Acid; Young Adult | 2011 |
Antiepileptic drugs for bipolar disorder and the risk of suicidal behavior: a 30-year observational study.
Topics: Adult; Anticonvulsants; Bipolar Disorder; Carbamazepine; Female; Humans; Lamotrigine; Lithium Compounds; Male; Propensity Score; Prospective Studies; Risk Factors; Suicide; Suicide, Attempted; Triazines; Valproic Acid | 2012 |
[Case of a 13-year-old boy with hyponatremia due to lamotrigine-induced syndrome of inappropriate secretion of antidiuretic hormone].
Topics: Adolescent; Anticonvulsants; Drug Therapy, Combination; Humans; Hyponatremia; Inappropriate ADH Syndrome; Lamotrigine; Male; Risperidone; Triazines; Valproic Acid | 2012 |
Amygdala functional connectivity predicts pharmacotherapy outcome in pediatric bipolar disorder.
Topics: Adolescent; Age Factors; Amygdala; Bipolar Disorder; Child; Female; Humans; Lamotrigine; Male; Nerve Net; Predictive Value of Tests; Psychomotor Performance; Risperidone; Treatment Outcome; Triazines; Valproic Acid; Young Adult | 2011 |
Mood stabilizers commonly restore staurosporine-induced increase of p53 expression and following decrease of Bcl-2 expression in SH-SY5Y cells.
Topics: Antimanic Agents; Apoptosis; Carbamazepine; Cell Line, Tumor; Enzyme Inhibitors; Gene Expression; Humans; Lamotrigine; Lithium; Neurons; Proto-Oncogene Proteins c-bcl-2; Staurosporine; Triazines; Tumor Suppressor Protein p53; Valproic Acid | 2012 |
Economic evaluation of anti-epileptic drug therapies with specific focus on teratogenic outcomes.
Topics: Abnormalities, Drug-Induced; Adolescent; Anticonvulsants; Carbamazepine; Cost-Benefit Analysis; Epilepsy; Female; Humans; Lamotrigine; Monte Carlo Method; Netherlands; Outcome Assessment, Health Care; Pregnancy; Pregnancy Complications; Quality-Adjusted Life Years; Triazines; Valproic Acid; Young Adult | 2012 |
Bone mineral density in adult patients treated with various antiepileptic drugs.
Topics: Absorptiometry, Photon; Adolescent; Adult; Aged; Anticonvulsants; Bone Density; Carbamazepine; Cross-Sectional Studies; Drug Therapy, Combination; Female; Fructose; Humans; Incidence; Lamotrigine; Levetiracetam; Male; Middle Aged; Oxcarbazepine; Piracetam; Topiramate; Triazines; Valproic Acid; Young Adult | 2012 |
Prevalence, utilization, and costs of antiepileptic drugs for epilepsy in Germany--a nationwide population-based study in children and adults.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Child; Databases, Factual; Epilepsy; Germany; Humans; Lamotrigine; Levetiracetam; Middle Aged; Piracetam; Population Surveillance; Prevalence; Retrospective Studies; Triazines; Valproic Acid; Young Adult | 2012 |
Levetiracetam-associated loss of libido and anhedonia.
Topics: Adult; Anhedonia; Anticonvulsants; Brain; Electroencephalography; Epilepsies, Myoclonic; Epilepsy, Complex Partial; Erectile Dysfunction; Gonadal Steroid Hormones; Humans; Lamotrigine; Levetiracetam; Libido; Magnetic Resonance Imaging; Male; Piracetam; Triazines; Valproic Acid; Young Adult | 2012 |
Late adverse effects of the coadministration of valproate and lamotrigine.
Topics: Adolescent; Anticonvulsants; Ataxia; Child; Drug Therapy, Combination; Epilepsy; Female; Headache; Humans; Lamotrigine; Longitudinal Studies; Male; Movement Disorders; Nervous System Diseases; Triazines; Valproic Acid; Vertigo | 2012 |
Effects of the anticonvulsant lacosamide compared to valproate and lamotrigine on cocaine-enhanced reward in rats.
Topics: Acetamides; Animals; Anticonvulsants; Cocaine; Lacosamide; Lamotrigine; Male; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Reward; Self Stimulation; Treatment Outcome; Triazines; Valproic Acid | 2012 |
Lamotrigine related myocarditis: case report.
Topics: Adolescent; Anticonvulsants; Electrocardiography; Epilepsy; Humans; Lamotrigine; Magnetic Resonance Imaging; Male; Myocarditis; Triazines; Troponin T; Valproic Acid | 2012 |
[Idiopathic generalized epilepsy in young women: choise of treatment strategy].
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Electroencephalography; Epilepsy, Generalized; Female; Fructose; Humans; Lamotrigine; Levetiracetam; Piracetam; Remission Induction; Topiramate; Triazines; Valproic Acid; Young Adult | 2012 |
Effects of mood stabilizers on marble-burying behavior in mice: involvement of GABAergic system.
Topics: Animals; Antipsychotic Agents; Baclofen; Behavior, Animal; Bicuculline; Carbamazepine; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Lamotrigine; Lithium Carbonate; Male; Mice; Mice, Inbred ICR; Motor Activity; Muscimol; Obsessive-Compulsive Disorder; Receptors, GABA-A; Triazines; Valproic Acid | 2013 |
Carbamazepine, but not valproate, displays pharmacoresistance in lamotrigine-resistant amygdala kindled rats.
Topics: Amygdala; Animals; Anticonvulsants; Carbamazepine; Drug Resistance; Epilepsy; Kindling, Neurologic; Lamotrigine; Male; Rats; Rats, Sprague-Dawley; Triazines; Valproic Acid | 2013 |
Effect of pregabalin add-on treatment on seizure control, quality of life, and anxiety in patients with brain tumour-related epilepsy: a pilot study.
Topics: Adult; Aged; Anticonvulsants; Anxiety; Benzodiazepines; Brain Neoplasms; Carbamazepine; Clobazam; Drug Therapy, Combination; Epilepsy; Female; Fructose; gamma-Aminobutyric Acid; Humans; Lamotrigine; Levetiracetam; Male; Middle Aged; Oxcarbazepine; Phenobarbital; Pilot Projects; Piracetam; Pregabalin; Quality of Life; Topiramate; Treatment Outcome; Triazines; Valproic Acid; Young Adult | 2012 |
Seizure control with antiepileptic drug therapy in 517 consecutive adult outpatients at the Kork Epilepsy Centre.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Ambulatory Care; Anticonvulsants; Carbamazepine; Cross-Sectional Studies; Drug Therapy, Combination; Epilepsy; Female; Humans; Lamotrigine; Levetiracetam; Male; Middle Aged; Piracetam; Treatment Outcome; Triazines; Valproic Acid; Young Adult | 2012 |
Exon-disrupting deletions of NRXN1 in idiopathic generalized epilepsy.
Topics: Adult; Age of Onset; Anticonvulsants; Calcium-Binding Proteins; Case-Control Studies; Cell Adhesion Molecules, Neuronal; DNA Copy Number Variations; Electroencephalography; Epilepsy, Generalized; Exons; Family; Female; Fructose; Gene Deletion; Genotype; Humans; Infant; Lamotrigine; Male; Microarray Analysis; Middle Aged; Nerve Tissue Proteins; Neural Cell Adhesion Molecules; Neuropsychological Tests; Odds Ratio; Pedigree; Topiramate; Triazines; Valproic Acid | 2013 |
Antiepileptic drugs (AEDs) during pregnancy and risk of congenital jaw and oral malformation.
Topics: Abnormalities, Drug-Induced; Adverse Drug Reaction Reporting Systems; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Data Mining; Datasets as Topic; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Jaw Abnormalities; Lamotrigine; Mouth Abnormalities; Pregnancy; Risk Factors; Topiramate; Triazines; Valproic Acid | 2013 |
Neural correlates of treatment response in depressed bipolar adolescents during emotion processing.
Topics: Adolescent; Anticonvulsants; Antidepressive Agents; Antipsychotic Agents; Aripiprazole; Bipolar Disorder; Brain; Citalopram; Depressive Disorder; Dibenzothiazepines; Drug Therapy, Combination; Emotions; Facial Expression; Female; Humans; Lamotrigine; Magnetic Resonance Imaging; Male; Piperazines; Psychotropic Drugs; Quetiapine Fumarate; Quinolones; Sertraline; Triazines; Valproic Acid | 2013 |
The prevalence of neurodevelopmental disorders in children prenatally exposed to antiepileptic drugs.
Topics: Adult; Anticonvulsants; Carbamazepine; Case-Control Studies; Child; Child Development Disorders, Pervasive; Child, Preschool; Developmental Disabilities; Female; Humans; Infant; Lamotrigine; Logistic Models; Pregnancy; Prenatal Exposure Delayed Effects; Prevalence; Prospective Studies; Risk Factors; Triazines; Valproic Acid | 2013 |
Valproate and lamotrigine in pediatric patients with refractory epilepsy: after the first year.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Female; Humans; Lamotrigine; Longitudinal Studies; Male; Time Factors; Treatment Outcome; Triazines; Valproic Acid | 2013 |
Pityriasis rosea-like eruption associated with lamotrigine.
Topics: Adult; Anticonvulsants; Drug Eruptions; Drug Hypersensitivity; Female; Humans; Lamotrigine; Myoclonic Epilepsy, Juvenile; Pityriasis Rosea; Triazines; Valproic Acid | 2013 |
[Comparison of neuroprotective effects of anticonvulsant drugs in brain injury therapy].
Topics: Amines; Animals; Animals, Outbred Strains; Anticonvulsants; Brain; Brain Injuries; Brain Ischemia; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Electric Stimulation; Fructose; Gabapentin; gamma-Aminobutyric Acid; Lamotrigine; Magnesium Sulfate; Mice; Rats; Seizures; Topiramate; Triazines; Valproic Acid | 2012 |
Valproate as a risk factor for lamotrigine discontinuation.
Topics: Adult; Anticonvulsants; Antidepressive Agents; Bipolar Disorder; Drug Therapy, Combination; Female; Humans; Lamotrigine; Male; Middle Aged; Mood Disorders; Retrospective Studies; Risk Factors; Treatment Outcome; Triazines; Valproic Acid; Withholding Treatment; Young Adult | 2013 |
Levetiracetam add-on therapy in Japanese patients with refractory partial epilepsy.
Topics: Adult; Anticonvulsants; Benzodiazepines; Clobazam; Drug Therapy, Combination; Epilepsies, Partial; Epilepsy, Complex Partial; Female; Fructose; Humans; Japan; Lamotrigine; Levetiracetam; Male; Middle Aged; Phenytoin; Piracetam; Retrospective Studies; Topiramate; Treatment Outcome; Triazines; Valproic Acid; Young Adult | 2013 |
Developmental outcomes at preschool age after fetal exposure to valproic acid and lamotrigine: cognitive, motor, sensory and behavioral function.
Topics: Anticonvulsants; Attention; Behavior; Child; Child, Preschool; Cognition; Faculty; Female; Humans; Lamotrigine; Male; Maternal-Fetal Exchange; Motor Skills; Parents; Pregnancy; Prenatal Exposure Delayed Effects; Prospective Studies; Surveys and Questionnaires; Triazines; Valproic Acid | 2013 |
Age and adverse drug reactions from psychopharmacological treatment: data from the AMSP drug surveillance programme in Switzerland.
Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Age Factors; Aged; Aged, 80 and over; Antimanic Agents; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Carbamazepine; Causality; Dibenzothiazepines; Drug-Related Side Effects and Adverse Reactions; Female; Galactorrhea; Humans; Lamotrigine; Logistic Models; Male; Middle Aged; Neuroleptic Malignant Syndrome; Olanzapine; Quetiapine Fumarate; Risperidone; Severity of Illness Index; Switzerland; Triazines; Valproic Acid; Weight Gain; Young Adult | 2013 |
Seizure control and treatment changes in pregnancy: observations from the EURAP epilepsy pregnancy registry.
Topics: Anticonvulsants; Carbamazepine; Female; Humans; Lamotrigine; Phenobarbital; Pregnancy; Pregnancy Complications; Registries; Seizures; Treatment Outcome; Triazines; Valproic Acid | 2013 |
Teratogenic potential of antiepileptic drugs in the zebrafish model.
Topics: Acetamides; Animals; Anticonvulsants; Carbamazepine; Disease Models, Animal; Ethosuximide; Female; Fructose; Humans; Lacosamide; Lamotrigine; Levetiracetam; Piracetam; Pregnancy; Teratogenesis; Topiramate; Triazines; United States; Valproic Acid; Zebrafish | 2013 |
The impact of the use of antiepileptic drugs on the growth of children.
Topics: Adolescent; Anticonvulsants; Body Height; Bone Diseases, Developmental; Calcium; Carbamazepine; Cell Size; Cells, Cultured; Child; Child, Preschool; Chondrocytes; Epilepsy; Female; Fructose; Growth Plate; Humans; Lamotrigine; Male; Oxcarbazepine; Topiramate; Triazines; Valproic Acid | 2013 |
Reproductive endocrine health in pubertal females with epilepsy on antiepileptic drugs: time to screen?
Topics: Adiposity; Adolescent; Anticonvulsants; Cohort Studies; Cross-Sectional Studies; Drug Evaluation, Preclinical; Endocrine Disruptors; Epilepsy; Female; Hirsutism; Humans; Hyperandrogenism; Lamotrigine; Levetiracetam; Piracetam; Reproductive Health; Triazines; Valproic Acid | 2014 |
Malformation risks of antiepileptic drug monotherapies in pregnancy: updated results from the UK and Ireland Epilepsy and Pregnancy Registers.
Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Epilepsy; Female; Humans; Ireland; Lamotrigine; Pregnancy; Prospective Studies; Registries; Triazines; United Kingdom; Valproic Acid; Young Adult | 2014 |
[Clinical efficacy and pharmacokinetics of lamotrigine for childhood-onset intractable epilepsy].
Topics: Adolescent; Age of Onset; Child; Drug Therapy, Combination; Female; Humans; Lamotrigine; Male; Seizures; Treatment Outcome; Triazines; Valproic Acid | 2014 |
Rapid development of severe skin rash after adding valproic acid in a case of bipolar depression treated with low-dose lamotrigine.
Topics: Antimanic Agents; Bipolar Disorder; Drug Eruptions; Drug Interactions; Drug Therapy, Combination; Female; Humans; Lamotrigine; Middle Aged; Triazines; Valproic Acid | 2014 |
Characterization of a lamotrigine-resistant kindled model of epilepsy in mice: evaluation of drug resistance mechanisms.
Topics: Animals; Anticonvulsants; Calcium Channels; Carbamazepine; Disease Models, Animal; Drug Resistance; Epilepsy; Kindling, Neurologic; Lamotrigine; Male; Mice; Pentylenetetrazole; Time Factors; Triazines; Valproic Acid; Voltage-Gated Sodium Channels | 2014 |
Hypokalemia and hypomagnesaemia related to levetiracetam use.
Topics: Adult; Anticonvulsants; Humans; Hypokalemia; Lamotrigine; Levetiracetam; Magnesium; Male; Nephritis, Interstitial; Piracetam; Potassium; Risk Factors; Seizures; Triazines; Valproic Acid | 2014 |
International prescribing patterns for mood illness: the International Mood Network (IMN).
Topics: Antidepressive Agents; Antimanic Agents; Antipsychotic Agents; Asia; Bipolar Disorder; Carbamazepine; Drug Prescriptions; Europe; Female; Humans; Lamotrigine; Lithium Compounds; Male; Middle Aged; Mood Disorders; North America; Practice Patterns, Physicians'; Psychotropic Drugs; South America; Triazines; Valproic Acid | 2014 |
The teratogenicity of the newer antiepileptic drugs - an update.
Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Epilepsy; Female; Fetus; Fructose; Humans; Lamotrigine; Levetiracetam; Piracetam; Pregnancy; Registries; Risk; Topiramate; Triazines; Valproic Acid | 2014 |
Simultaneous analysis of 22 antiepileptic drugs in postmortem blood, serum and plasma using LC-MS-MS with a focus on their role in forensic cases.
Topics: Amines; Anticonvulsants; Carbamazepine; Chromatography, Liquid; Cyclohexanecarboxylic Acids; Drug Monitoring; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Levetiracetam; Limit of Detection; Nipecotic Acids; Oxcarbazepine; Phenytoin; Piracetam; Pregabalin; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Tiagabine; Topiramate; Triazines; Valproic Acid | 2014 |
Effect of comedication on lamotrigine clearance in Korean epilepsy patients.
Topics: Adult; Anticonvulsants; Dose-Response Relationship, Drug; Drug Interactions; Epilepsy; Female; Half-Life; Humans; Lamotrigine; Male; Middle Aged; Phenytoin; Triazines; Valproic Acid | 2015 |
Validation of a multigenic model to predict seizure control in newly treated epilepsy.
Topics: Adult; Algorithms; Anticonvulsants; Artificial Intelligence; Australia; Biomarkers, Pharmacological; Carbamazepine; Cohort Studies; Epilepsy; Female; Humans; Lamotrigine; Logistic Models; Male; Models, Genetic; Polymorphism, Single Nucleotide; Seizures; Treatment Outcome; Triazines; United Kingdom; Valproic Acid | 2014 |
Effects of mood-stabilizing drugs on dendritic outgrowth and synaptic protein levels in primary hippocampal neurons.
Topics: Animals; Antimanic Agents; Bipolar Disorder; Brain-Derived Neurotrophic Factor; Cell Adhesion Molecules, Neuronal; Dendrites; Disks Large Homolog 4 Protein; Hippocampus; Intracellular Signaling Peptides and Proteins; Lamotrigine; Lithium Compounds; Membrane Proteins; Neurons; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Rats; Synaptophysin; Triazines; Valproic Acid | 2015 |
Atherosclerotic effects of long-term old and new antiepileptic drugs monotherapy: a cross-sectional comparative study.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Carotid Arteries; Carotid Intima-Media Thickness; Cross-Sectional Studies; Enzyme-Linked Immunosorbent Assay; Epilepsies, Partial; Epilepsy, Generalized; Female; Fructose; Humans; Intracranial Arteriosclerosis; Lamotrigine; Levetiracetam; Male; Piracetam; Topiramate; Triazines; Valproic Acid | 2015 |
Nonlinear mixed effects modelling approach in investigating phenobarbital pharmacokinetic interactions in epileptic patients.
Topics: Adult; Anticonvulsants; Carbamazepine; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Fructose; Humans; Lamotrigine; Male; Middle Aged; Models, Biological; Nonlinear Dynamics; Phenobarbital; Topiramate; Triazines; Valproic Acid | 2015 |
Predominant polarity in bipolar disorder and validation of the polarity index in a German sample.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Antidepressive Agents; Antipsychotic Agents; Bipolar Disorder; Carbamazepine; Female; Germany; Humans; Lamotrigine; Lithium Compounds; Male; Middle Aged; Psychiatric Status Rating Scales; Retrospective Studies; Severity of Illness Index; Triazines; Valproic Acid; Young Adult | 2014 |
Reversal of novelty-induced hippocampal c-Fos expression in GluA1 subunit-deficient mice by chronic treatment targeting glutamatergic transmission.
Topics: Animals; CA3 Region, Hippocampal; Exploratory Behavior; Female; Fructose; Glutamic Acid; Hippocampus; Lamotrigine; Lithium Compounds; Male; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Neuroprotective Agents; Nitriles; Proto-Oncogene Proteins c-fos; Pyridones; Receptors, AMPA; Synaptic Transmission; Topiramate; Triazines; Valproic Acid | 2014 |
Gender differences in the treatment of patients with bipolar disorder: a study of 7354 patients.
Topics: Adult; Aged; Antidepressive Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Drug Prescriptions; Electroconvulsive Therapy; Female; Humans; Lamotrigine; Lithium Compounds; Logistic Models; Male; Middle Aged; Practice Patterns, Physicians'; Psychotherapy; Registries; Retrospective Studies; Sex Factors; Sweden; Triazines; Valproic Acid | 2015 |
IQ at 6 years after in utero exposure to antiepileptic drugs: a controlled cohort study.
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Child Development; Epilepsy; Female; Humans; Intelligence; Lamotrigine; Male; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Prospective Studies; Triazines; Valproic Acid | 2015 |
Fine-tuning risk assessment with antiepileptic drug use in pregnancy.
Topics: Anticonvulsants; Carbamazepine; Child Development; Epilepsy; Female; Humans; Intelligence; Lamotrigine; Male; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Triazines; Valproic Acid | 2015 |
Valproate and pregnancy: think again.
Topics: Anticonvulsants; Carbamazepine; Child Development; Epilepsy; Female; Humans; Intelligence; Lamotrigine; Male; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Triazines; Valproic Acid | 2015 |
Antiepileptic drugs in Rett Syndrome.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Lamotrigine; Male; Middle Aged; Retrospective Studies; Rett Syndrome; Treatment Outcome; Triazines; Valproic Acid | 2015 |
Effects of antiepileptic drug monotherapy on one-carbon metabolism and DNA methylation in patients with epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Case-Control Studies; Cross-Sectional Studies; DNA Methylation; Epilepsy; Female; Folic Acid; Heterocyclic Compounds; Homocysteine; Humans; Lamotrigine; Long Interspersed Nucleotide Elements; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Triazines; Valproic Acid; Vitamin B 12; Young Adult | 2015 |
Effects of UGT1A4 genetic polymorphisms on serum lamotrigine concentrations in Chinese children with epilepsy.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; China; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Genotype; Glucuronosyltransferase; Humans; Infant; Lamotrigine; Male; Polymorphism, Single Nucleotide; Prospective Studies; Triazines; Valproic Acid | 2015 |
Synergistic effect of docosahexaenoic acid on anticonvulsant activity of valproic acid and lamotrigine in animal seizure models.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Docosahexaenoic Acids; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Electroshock; Epilepsy; Kindling, Neurologic; Lamotrigine; Male; Mice; Pentylenetetrazole; Phenytoin; Rats; Rats, Wistar; Seizures; Triazines; Valproic Acid | 2015 |
A prospective study of adverse drug reactions to antiepileptic drugs in children.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cognition Disorders; Drug Therapy, Combination; Epilepsy; Female; Follow-Up Studies; Humans; Lamotrigine; Male; Prospective Studies; Severity of Illness Index; Sleep Disorders, Intrinsic; Triazines; United Kingdom; Valproic Acid | 2015 |
Dose-dependent teratogenicity of valproate in mono- and polytherapy: an observational study.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Anticonvulsants; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsy; Female; Follow-Up Studies; Humans; Infant, Newborn; Lamotrigine; Male; Middle Aged; Pregnancy; Pregnancy Complications; Prospective Studies; Registries; Teratogenesis; Triazines; Valproic Acid; Young Adult | 2015 |
Involvement of p38 MAPK in the Drug Resistance of Refractory Epilepsy Through the Regulation Multidrug Resistance-Associated Protein 1.
Topics: Animals; Chromatography, High Pressure Liquid; Drug Resistance; Epilepsy; Lamotrigine; Male; Microdialysis; Multidrug Resistance-Associated Proteins; p38 Mitogen-Activated Protein Kinases; Rats; Rats, Wistar; Triazines; Valproic Acid | 2015 |
Comparative Long-Term Effectiveness of a Monotherapy with Five Antiepileptic Drugs for Focal Epilepsy in Adult Patients: A Prospective Cohort Study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Epilepsies, Partial; Female; Fructose; Humans; Lamotrigine; Male; Middle Aged; Oxcarbazepine; Prospective Studies; Seizures; Topiramate; Treatment Failure; Triazines; Valproic Acid; Young Adult | 2015 |
Spontaneous reporting of Stevens-Johnson syndrome and toxic epidermal necrolysis associated with antiepileptic drugs.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amines; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Databases, Factual; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant; Lamotrigine; Male; Middle Aged; Oxcarbazepine; Pharmacovigilance; Phenobarbital; Spain; Stevens-Johnson Syndrome; Triazines; Valproic Acid; Young Adult | 2015 |
A LC-MS/MS method for therapeutic drug monitoring of carbamazepine, lamotrigine and valproic acid in DBS.
Topics: Anticonvulsants; Calibration; Carbamazepine; Child; Chromatography, Liquid; Dried Blood Spot Testing; Drug Monitoring; Epilepsy; Humans; Lamotrigine; Reproducibility of Results; Tandem Mass Spectrometry; Triazines; Valproic Acid | 2015 |
[Position Statement of Hungarian Epilepsy League: The use of valproate preparations for epilepsy in pregnancy and in women of childbearing age].
Topics: Adolescent; Adult; Anticonvulsants; Cognition; Contraception; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsy; Female; Humans; Hungary; Insurance Coverage; Insurance, Health; Lamotrigine; Levetiracetam; Middle Aged; Piracetam; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Triazines; Valproic Acid; Young Adult | 2015 |
LIS1-associated classic lissencephaly: A retrospective, multicenter survey of the epileptogenic phenotype and response to antiepileptic drugs.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Adolescent; Adult; Anticonvulsants; Brain; Child; Child, Preschool; Classical Lissencephalies and Subcortical Band Heterotopias; Drug Resistant Epilepsy; Electroencephalography; Female; Humans; Infant; Lamotrigine; Male; Microtubule-Associated Proteins; Phenobarbital; Phenotype; Retrospective Studies; Treatment Outcome; Triazines; Valproic Acid; Vigabatrin; Young Adult | 2016 |
Long-term Effectiveness of Antiepileptic Drug Monotherapy in Partial Epileptic Patients: A 7-year Study in an Epilepsy Center in China.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; China; Epilepsies, Partial; Female; Fructose; Humans; Lamotrigine; Levetiracetam; Male; Middle Aged; Oxcarbazepine; Piracetam; Retrospective Studies; Topiramate; Treatment Outcome; Triazines; Valproic Acid; Young Adult | 2015 |
Pharmacological outcomes in juvenile myoclonic epilepsy: Support for sodium valproate.
Topics: Adolescent; Adult; Anticonvulsants; Child; Comorbidity; Drug Resistant Epilepsy; Female; Follow-Up Studies; Humans; Lamotrigine; Levetiracetam; Male; Mental Disorders; Myoclonic Epilepsy, Juvenile; Piracetam; Retrospective Studies; Sex Factors; Treatment Outcome; Triazines; Valproic Acid; Young Adult | 2016 |
Specific adverse effects of antiepileptic drugs--A true-to-life monotherapy study.
Topics: Adult; Aged; Anticonvulsants; Anxiety; Carbamazepine; Depression; Drug-Related Side Effects and Adverse Reactions; Epilepsy; Fatigue; Female; Humans; Lamotrigine; Levetiracetam; Male; Middle Aged; Piracetam; Quality of Life; Triazines; Valproic Acid; Young Adult | 2016 |
Effects of UGT2B7 Genetic Polymorphisms on Serum Concentrations of Valproic Acid in Chinese Children With Epilepsy Comedicated With Lamotrigine.
Topics: Adolescent; Age Factors; Anticonvulsants; Asian People; Child; Child, Preschool; Chromatography, High Pressure Liquid; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Fluorescence Polarization Immunoassay; Genotype; Glucuronosyltransferase; Humans; Infant; Lamotrigine; Male; Mutation; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Sequence Analysis, DNA; Triazines; Valproic Acid | 2016 |
Clinical correlates of sustained response to individual drugs used in naturalistic treatment of patients with bipolar disorder.
Topics: Adult; Antidepressive Agents; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Child; Child Abuse; Drug Therapy, Combination; Female; Humans; Lamotrigine; Lithium Compounds; Male; Middle Aged; Mood Disorders; Neuropsychological Tests; Outpatients; Parents; Substance-Related Disorders; Treatment Outcome; Triazines; Valproic Acid | 2016 |
Anti-epileptic drugs and bone loss: Phenytoin reduces pro-collagen I and alters the electrophoretic mobility of osteonectin in cultured bone cells.
Topics: Animals; Anticonvulsants; Blotting, Western; Bone and Bones; Carbamazepine; Cell Line; Collagen Type I; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Fluorescent Antibody Technique; Fructose; Gene Expression Profiling; Lamotrigine; Levetiracetam; Microscopy, Confocal; Osteoblasts; Osteonectin; Phenytoin; Piracetam; Procollagen; Real-Time Polymerase Chain Reaction; Topiramate; Triazines; Valproic Acid | 2016 |
The effects of co-medications on lamotrigine clearance in Japanese children with epilepsy.
Topics: Adolescent; Anticonvulsants; Benzodiazepines; Carbamazepine; Child; Child, Preschool; Clobazam; Clonazepam; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Infant; Infant, Newborn; Isoxazoles; Japan; Lamotrigine; Levetiracetam; Male; Phenobarbital; Phenytoin; Piracetam; Triazines; Valproic Acid; Young Adult; Zonisamide | 2016 |
An investigation of the influence of patient-related factors and comedications on lamotrigine clearance in patients with epilepsy.
Topics: Adult; Anticonvulsants; Body Weight; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Kinetics; Lamotrigine; Male; Triazines; Valproic Acid; Young Adult | 2016 |
Comparison of body composition in persons with epilepsy on conventional & new antiepileptic drugs.
Topics: Adult; Anticonvulsants; Benzodiazepines; Body Composition; Body Water; Body Weight; Carbamazepine; Clobazam; Cross-Sectional Studies; Epilepsy; Female; Humans; Lamotrigine; Levetiracetam; Lipids; Male; Middle Aged; Piracetam; Triazines; Valproic Acid | 2016 |
Early-life epileptic encephalopathy secondary to SZT2 pathogenic recessive variants.
Topics: Anticonvulsants; Brain; Child, Preschool; Drug Resistant Epilepsy; Electroencephalography; Humans; Infant; Lamotrigine; Magnetic Resonance Imaging; Male; Mutation; Nerve Tissue Proteins; Periventricular Nodular Heterotopia; Treatment Outcome; Triazines; Valproic Acid | 2016 |
The Impact of Pharmacokinetic Interactions With Eslicarbazepine Acetate Versus Oxcarbazepine and Carbamazepine in Clinical Practice.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Dibenzazepines; Drug Interactions; Drug Monitoring; Female; Humans; Infant; Infant, Newborn; Lamotrigine; Male; Middle Aged; Norway; Oxcarbazepine; Triazines; Valproic Acid; Young Adult | 2016 |
Comparative persistence of antiepileptic drugs in patients with epilepsy: A STROBE-compliant retrospective cohort study.
Topics: Adolescent; Adult; Aged; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsy; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Hospitalization; Humans; Lamotrigine; Male; Medication Adherence; Middle Aged; Oxcarbazepine; Phenytoin; Proportional Hazards Models; Retrospective Studies; Risk Factors; Taiwan; Topiramate; Triazines; Valproic Acid; Young Adult | 2016 |
Efficacy and tolerability of anti-epileptic drugs-an internet study.
Topics: Adult; Anticonvulsants; Carbamazepine; Depression; Epilepsy; Female; Humans; Internet; Lamotrigine; Levetiracetam; Male; Middle Aged; Piracetam; Prospective Studies; Seizures; Self Report; Treatment Outcome; Triazines; United Kingdom; Valproic Acid | 2017 |
Epilepsy with myoclonic absences: Electroclinical characteristics in a distinctive pediatric epilepsy phenotype.
Topics: Anticonvulsants; Brain; Child; Child, Preschool; Cohort Studies; Drug Therapy, Combination; Electroencephalography; Epilepsies, Myoclonic; Female; Humans; Lamotrigine; Male; Phenotype; Prognosis; Seizures; Treatment Outcome; Triazines; Valproic Acid | 2016 |
Pharmacokinetic Drug-Drug Interactions of Mood Stabilizers and Risperidone in Patients Under Combined Treatment.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Carbamazepine; Drug Interactions; Drug Therapy, Combination; Female; Humans; Lamotrigine; Male; Middle Aged; Paliperidone Palmitate; Risperidone; Triazines; Valproic Acid; Young Adult | 2016 |
Effect of lamotrigine, levetiracetam & topiramate on neurobehavioural parameters & oxidative stress in comparison with valproate in rats.
Topics: Animals; Brain; Fructose; Glutathione; Lamotrigine; Learning; Levetiracetam; Male; Malondialdehyde; Memory; Oxidative Stress; Piracetam; Rats; Superoxide Dismutase; Topiramate; Triazines; Valproic Acid | 2016 |
Antiepileptic drugs in migraine and epilepsy: Who is at increased risk of adverse events?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Child; Epilepsy; Female; Humans; Lamotrigine; Male; Middle Aged; Migraine Disorders; Topiramate; Valproic Acid; Young Adult | 2018 |
Effectiveness and tolerability of antiepileptic drugs in 104 girls with Rett syndrome.
Topics: Adolescent; Adult; Age Factors; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Female; Humans; Lamotrigine; Outcome Assessment, Health Care; Rett Syndrome; Triazines; Valproic Acid; Young Adult | 2017 |
Anti-Epileptic Drug Combination Efficacy in an In Vitro Seizure Model - Phenytoin and Valproate, Lamotrigine and Valproate.
Topics: Animals; Anticonvulsants; Drug Combinations; Drug Interactions; Female; Hippocampus; In Vitro Techniques; Lamotrigine; Male; Models, Theoretical; Phenytoin; Rats; Rats, Wistar; Seizures; Treatment Outcome; Triazines; Valproic Acid | 2017 |
Association between antiepileptic drug dose and long-term response in patients with refractory epilepsy.
Topics: Adult; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resistant Epilepsy; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Lamotrigine; Longitudinal Studies; Male; Middle Aged; Phenytoin; Retrospective Studies; Time Factors; Treatment Outcome; Triazines; Valproic Acid | 2017 |
An investigation of the characteristics of outpatients with epilepsy and antiepileptic drug utilization in a multicenter cross-sectional study in China.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; China; Cross-Sectional Studies; Drug Combinations; Drug Utilization; Epilepsy; Female; Humans; Lamotrigine; Male; Middle Aged; Outpatient Clinics, Hospital; Oxcarbazepine; Tertiary Care Centers; Treatment Outcome; Triazines; Valproic Acid; Young Adult | 2017 |
Assessment of atherosclerotic risk among patients with epilepsy on valproic acid, lamotrigine, and carbamazepine treatment.
Topics: Adult; Anticonvulsants; Carbamazepine; Cholesterol; Cross-Sectional Studies; Epilepsy; Female; Humans; Intracranial Arteriosclerosis; Lamotrigine; Male; Retrospective Studies; Statistics, Nonparametric; Valproic Acid | 2017 |
Patterns of antiepileptic drug prescription in Sweden: A register-based approach.
Topics: Adult; Aged; Anticonvulsants; Carbamazepine; Drug Prescriptions; Epilepsy; Female; Humans; Lamotrigine; Male; Middle Aged; Registries; Sweden; Triazines; Valproic Acid | 2017 |
Lamotrigine Drug Interactions in Combination Therapy and the Influence of Therapeutic Drug Monitoring on Clinical Outcomes of Adult Patients.
Topics: Adult; Anticonvulsants; Carbamazepine; Clonazepam; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Female; Fructose; Humans; Lamotrigine; Levetiracetam; Male; Phenytoin; Piracetam; Seizures; Topiramate; Triazines; Valproic Acid | 2017 |
Rationale for an adjunctive therapy with fenofibrate in pharmacoresistant nocturnal frontal lobe epilepsy.
Topics: Adult; Animals; Anticonvulsants; Benzodiazepines; Carbamazepine; Clobazam; Disease Models, Animal; Drug Resistant Epilepsy; Drug Therapy, Combination; Electroencephalography; Epilepsy, Frontal Lobe; Female; Fenofibrate; Humans; Lamotrigine; Levetiracetam; Male; Mice; Mice, Transgenic; Middle Aged; Mutation; Oxcarbazepine; Piracetam; Polysomnography; PPAR alpha; Receptors, Nicotinic; Triazines; Valproic Acid; Young Adult | 2017 |
Comparative effectiveness of antiepileptic drugs in patients with mesial temporal lobe epilepsy with hippocampal sclerosis.
Topics: Adolescent; Adult; Aged; Amines; Anticonvulsants; Ataxia; Benzodiazepines; Carbamazepine; Clobazam; Cyclohexanecarboxylic Acids; Databases, Factual; Diplopia; Dizziness; Epilepsy, Temporal Lobe; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; Humans; Lamotrigine; Lethargy; Male; Middle Aged; Oxcarbazepine; Pregabalin; Retrospective Studies; Sclerosis; Topiramate; Treatment Outcome; Triazines; Valproic Acid; Vertigo; Vigabatrin; Vision Disorders; Young Adult | 2017 |
Stevens - Johnson Syndrome Induced by Combination of Lamotrigine and Valproic Acid in a 9-Year-Old Boy.
Topics: Anticonvulsants; Child; Drug Therapy, Combination; Humans; Lamotrigine; Male; Stevens-Johnson Syndrome; Valproic Acid | 2017 |
Associations between use of mood stabilizers and risk of cataract: A population-based nested case-control study.
Topics: Adult; Aged; Antimanic Agents; Bipolar Disorder; Carbamazepine; Case-Control Studies; Cataract; Databases, Factual; Female; Humans; Lamotrigine; Lithium; Male; Middle Aged; Risk; Schizophrenia; Taiwan; Triazines; Valproic Acid | 2018 |
Fetal Valproate Syndrome - Still a Problem Today!
Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Cesarean Section; Drug Therapy, Combination; Epilepsy; Female; Folic Acid; Humans; Infant, Newborn; Infant, Premature, Diseases; Lamotrigine; Male; Pregnancy; Pregnancy Complications; Pregnancy Trimester, Second; Risk Factors; Syndrome; Valproic Acid | 2017 |
Carbamazepine, lamotrigine, levetiracetam and valproic acid in dried blood spots with liquid chromatography tandem mass spectrometry; method development and validation.
Topics: Carbamazepine; Chromatography, Liquid; Dried Blood Spot Testing; Female; Humans; Lamotrigine; Levetiracetam; Linear Models; Male; Piracetam; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Triazines; Valproic Acid | 2018 |
A rapid and simple HPLC-MS/MS method for the simultaneous quantification of valproic acid and its five metabolites in human plasma and application to study pharmacokinetic interaction in Chinese epilepsy patients.
Topics: Adolescent; Adult; Anticonvulsants; Asian People; Chromatography, High Pressure Liquid; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Lamotrigine; Male; Sensitivity and Specificity; Tandem Mass Spectrometry; Time Factors; Triazines; Valproic Acid; Young Adult | 2018 |
Mood-Stabilizing Anticonvulsants, Spina Bifida, and Folate Supplementation: Commentary.
Topics: Anticonvulsants; Antimanic Agents; Bipolar Disorder; Carbamazepine; Dietary Supplements; Female; Folic Acid; Humans; Lamotrigine; Neural Tube Defects; Pregnancy; Pregnancy Complications; Spinal Dysraphism; Triazines; Valproic Acid | 2018 |
Population pharmacokinetics of lamotrigine co-administered with valproic acid in Chinese epileptic children using nonlinear mixed effects modeling.
Topics: Adolescent; Anticonvulsants; Asian People; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Female; Genotype; Glucuronosyltransferase; Humans; Lamotrigine; Male; Models, Biological; Nonlinear Dynamics; Polymorphism, Single Nucleotide; Triazines; Valproic Acid | 2018 |
Disabling tremor induced by long-term use of sodium valproate and lamotrigine: Case report.
Topics: Amantadine; Anticonvulsants; Antiparkinson Agents; Dyskinesia, Drug-Induced; Dyskinesias; Humans; Lamotrigine; Male; Middle Aged; Triazines; Trihexyphenidyl; Valproic Acid | 2017 |
Utilization of Antiepileptic Medicines in Swedish Children and Adolescents with Different Diagnoses.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Drug Prescriptions; Drug Utilization; Epilepsy; Female; Humans; Infant; Infant, Newborn; Lamotrigine; Male; Mental Disorders; Migraine Disorders; Off-Label Use; Pain; Practice Patterns, Physicians'; Prescription Drugs; Registries; Sex Factors; Sweden; Triazines; Valproic Acid | 2018 |
Effect of antiepileptic drug comedication on lamotrigine concentrations.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Fructose; Humans; Lamotrigine; Male; Middle Aged; Retrospective Studies; Topiramate; Triazines; Valproic Acid; Young Adult | 2018 |
Observational multicentre study into the use of antiepileptic drugs in Spanish neurology consultations.
Topics: Adult; Anticonvulsants; Drug Therapy, Combination; Epilepsy; Female; Humans; Lamotrigine; Levetiracetam; Male; Neurology; Referral and Consultation; Seizures; Spain; Valproic Acid | 2020 |
Double cortex syndrome in a male patient without lissencephaly.
Topics: Adult; Anticonvulsants; Classical Lissencephalies and Subcortical Band Heterotopias; Electroencephalography; Humans; Lamotrigine; Levetiracetam; Magnetic Resonance Imaging; Male; Mutation; Seizures; Valproic Acid | 2020 |
Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) 2018 guidelines for the management of patients with bipolar disorder.
Topics: Adolescent; Aged; Algorithms; Antipsychotic Agents; Bipolar Disorder; Bupropion; Child; Evidence-Based Medicine; Female; Humans; Lamotrigine; Lithium Compounds; Olanzapine; Quetiapine Fumarate; Societies, Medical; Suicide; Suicide Prevention; Valproic Acid | 2018 |
Time course of reversal of valproate-mediated inhibition of lamotrigine.
Topics: Administration, Oral; Adult; Anticonvulsants; Drug Interactions; Drug Substitution; Female; Humans; Lamotrigine; Male; Time Factors; Triazines; Valproic Acid | 2018 |
Juvenile myoclonic epilepsy refractory to treatment in a tertiary referral center.
Topics: Adolescent; Adult; Anticonvulsants; Child; Drug Resistant Epilepsy; Electroencephalography; Female; Humans; Lamotrigine; Levetiracetam; Male; Middle Aged; Myoclonic Epilepsy, Juvenile; Retrospective Studies; Tertiary Care Centers; Treatment Outcome; Valproic Acid | 2018 |
Comparative risk of major congenital malformations with eight different antiepileptic drugs: a prospective cohort study of the EURAP registry.
Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Epilepsy; Female; Humans; Lamotrigine; Levetiracetam; Logistic Models; Male; Oxcarbazepine; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Topiramate; Valproic Acid; Young Adult | 2018 |
Interaction between ABCG2 421C>A polymorphism and valproate in their effects on steady-state disposition of lamotrigine in adults with epilepsy.
Topics: Adolescent; Adult; Aged; Alleles; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Glucuronosyltransferase; Humans; Lamotrigine; Male; Middle Aged; Neoplasm Proteins; Polymorphism, Single Nucleotide; Prospective Studies; Valproic Acid; Young Adult | 2018 |
Obstetric outcomes and effects on babies born to women treated for epilepsy during pregnancy in a resource limited setting: a comparative cohort study.
Topics: Abortion, Spontaneous; Adolescent; Adult; Anticonvulsants; Body Height; Body Weight; Carbamazepine; Case-Control Studies; Child Development; Clobazam; Congenital Abnormalities; Developing Countries; Drug Therapy, Combination; Epilepsy; Female; Humans; Infant; Infant, Low Birth Weight; Infant, Newborn; Lamotrigine; Live Birth; Medication Adherence; Pregnancy; Pregnancy Complications; Premature Birth; Prenatal Exposure Delayed Effects; Sri Lanka; Topiramate; Valproic Acid; Young Adult | 2018 |
Levetiracetam and lamotrigine effects as mono- and polytherapy on bone mineral density in epileptic patients.
Topics: Adolescent; Adult; Amino Acids; Anticonvulsants; Biomarkers; Bone Density; Bone Remodeling; Case-Control Studies; Drug Therapy, Combination; Epilepsy; Female; Humans; Lamotrigine; Levetiracetam; Male; Osteocalcin; Piracetam; Triazines; Valproic Acid; Young Adult | 2018 |
Clinically Relevant Effect of UGT1A4*3 on Lamotrigine Serum Concentration Is Restricted to Postmenopausal Women-A Study Matching Therapeutic Drug Monitoring and Genotype Data From 534 Patients.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Alleles; Databases, Factual; Drug Monitoring; Female; Genotype; Glucuronosyltransferase; Humans; Lamotrigine; Male; Middle Aged; Models, Biological; Postmenopause; Retrospective Studies; Sex Factors; Valproic Acid; Young Adult | 2018 |
A Population Pharmacokinetic-Pharmacogenetic Model of Lamotrigine in Chinese Children With Epilepsy.
Topics: Anticonvulsants; Asian People; ATP-Binding Cassette Transporters; Child; Drug Interactions; Epilepsy; Genotype; Hepatocyte Nuclear Factor 4; Humans; Inactivation, Metabolic; Lamotrigine; Models, Biological; Oxcarbazepine; Pharmacogenetics; Valproic Acid | 2018 |
Ictal Source Locations and Cortico-Thalamic Connectivity in Childhood Absence Epilepsy: Associations with Treatment Response.
Topics: Anticonvulsants; Cerebral Cortex; Child; Child, Preschool; China; Epilepsy, Absence; Female; Gray Matter; Humans; Lamotrigine; Magnetic Resonance Imaging; Magnetoencephalography; Male; Nerve Net; Thalamus; Treatment Outcome; Valproic Acid | 2019 |
Mood stabilisers and risk of stroke in bipolar disorder.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Antimanic Agents; Bipolar Disorder; Carbamazepine; Cross-Over Studies; Databases, Factual; Female; Humans; Lamotrigine; Lithium Compounds; Male; Middle Aged; Retrospective Studies; Stroke; Taiwan; Valproic Acid; Young Adult | 2019 |
Adverse drug reactions associated with six commonly used antiepileptic drugs in southern China from 2003 to 2015.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Child; Child, Preschool; China; Epilepsy; Female; Humans; Infant; Lamotrigine; Levetiracetam; Male; Middle Aged; Outpatients; Oxcarbazepine; Topiramate; Valproic Acid; Young Adult | 2019 |
The influence of concomitant antiepileptic drugs on lamotrigine serum concentrations in Northwest Chinese Han population with epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Asian People; Carbamazepine; Child; Child, Preschool; China; Drug Therapy, Combination; Epilepsy; Female; Humans; Lamotrigine; Male; Middle Aged; Oxcarbazepine; Retrospective Studies; Topiramate; Triazines; Valproic Acid; Young Adult | 2019 |
Accidental injuries in patients with generalized tonic-clonic seizures. A multicenter, observational, cross-sectional study (QUIN-GTC study).
Topics: Accidental Injuries; Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Cross-Sectional Studies; Epilepsy, Tonic-Clonic; Female; Humans; Lamotrigine; Levetiracetam; Male; Middle Aged; Quality of Life; Seizures; Valproic Acid; Young Adult | 2019 |
Fetal antiepileptic drug exposure and learning and memory functioning at 6 years of age: The NEAD prospective observational study.
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Epilepsy; Female; Humans; Lamotrigine; Learning; Memory; Memory Disorders; Mothers; Phenytoin; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Prospective Studies; Valproic Acid | 2019 |
Lamotrigine drug interactions in combination therapy and the influence of therapeutic drug monitoring on clinical outcomes in paediatric patients.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Czech Republic; Dose-Response Relationship, Drug; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Epilepsy; Female; Humans; Incidence; Lamotrigine; Levetiracetam; Male; Metabolic Clearance Rate; Severity of Illness Index; Topiramate; Valproic Acid | 2019 |
Levetiracetam administration is correlated with lower mortality in patients with mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes: a retrospective study.
Topics: Acidosis, Lactic; Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Female; Humans; Lamotrigine; Levetiracetam; Male; Mitochondrial Encephalomyopathies; Oxcarbazepine; Prospective Studies; Retrospective Studies; Stroke; Topiramate; Valproic Acid | 2019 |
Developmental outcomes at age four following maternal antiepileptic drug use.
Topics: Adult; Anticonvulsants; Carbamazepine; Child Development; Child, Preschool; Cohort Studies; Epilepsy; Female; Follow-Up Studies; Humans; Lamotrigine; Male; New Zealand; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Retrospective Studies; Valproic Acid | 2019 |
Case of Childhood Absence Epilepsy with Focal Spikes.
Topics: Action Potentials; Anticonvulsants; Child; Drug Substitution; Electroencephalography; Epilepsy, Absence; Follow-Up Studies; Humans; Lamotrigine; Magnetic Resonance Imaging; Male; Neuroimaging; Sleep Disorders, Intrinsic; Valproic Acid; Video Recording | 2019 |
Antiepileptic Drug Treatment Patterns in Women of Childbearing Age With Epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Anxiety Disorders; Comorbidity; Dissociative Disorders; Epilepsies, Partial; Epilepsy, Generalized; Female; Headache Disorders; Humans; Lamotrigine; Levetiracetam; Mental Disorders; Migraine Disorders; Mood Disorders; Oxcarbazepine; Phenytoin; Retrospective Studies; Risk; Teratogens; Topiramate; Valproic Acid; Young Adult | 2019 |
Differential effects of antiepileptic drugs on human bone cells.
Topics: Anticonvulsants; Bone and Bones; Bone Development; Carbamazepine; Cell Differentiation; Humans; Lamotrigine; Osteoblasts; Osteogenesis; Primary Cell Culture; Topiramate; Valproic Acid | 2019 |
Behavioral problems in children of mothers with epilepsy prenatally exposed to valproate, carbamazepine, lamotrigine, or levetiracetam monotherapy.
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Child Behavior Disorders; Epilepsy; Female; Humans; Lamotrigine; Levetiracetam; Male; Mothers; Pregnancy; Prenatal Exposure Delayed Effects; Prospective Studies; Registries; Social Behavior Disorders; Valproic Acid | 2019 |
Long-term follow-up with therapeutic drug monitoring of antiepileptic drugs in patients with juvenile myoclonic epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Drug Monitoring; Female; Follow-Up Studies; Humans; Lamotrigine; Levetiracetam; Male; Medication Adherence; Myoclonic Epilepsy, Juvenile; Norway; Retrospective Studies; Treatment Outcome; Valproic Acid; Young Adult | 2019 |
Management and attitudes toward patients with epilepsy in general practice: How far have we come in three decades?
Topics: Adult; Anticonvulsants; Attitude of Health Personnel; Australia; Carbamazepine; Clinical Competence; Electroencephalography; Epilepsy; Female; Follow-Up Studies; General Practitioners; Humans; Lamotrigine; Levetiracetam; Magnetic Resonance Imaging; Male; Middle Aged; Neurology; Phenytoin; Referral and Consultation; Surveys and Questionnaires; Valproic Acid | 2019 |
Use of antiepileptic drugs in women of fertile age.
Topics: Adolescent; Adult; Anticonvulsants; Denmark; Epilepsy; Female; Gabapentin; Humans; Lamotrigine; Levetiracetam; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Valproic Acid; Young Adult | 2019 |
Treatment and challenges with antiepileptic drugs in patients with juvenile myoclonic epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Cohort Studies; Female; Humans; Lamotrigine; Levetiracetam; Male; Myoclonic Epilepsy, Juvenile; Myoclonus; Norway; Quality of Life; Seizures; Valproic Acid; Young Adult | 2019 |
A 16q22.2-q23.1 deletion identified in a male infant with West syndrome.
Topics: Anticonvulsants; Chromosomes, Human, Pair 16; Epilepsy; Humans; Infant; Intellectual Disability; Lamotrigine; Male; Phenobarbital; Seizures; Sequence Deletion; Spasms, Infantile; Valproic Acid | 2019 |
Anti-epileptic drug and folic acid usage during pregnancy, seizure and malformation outcomes: Changes over two decades in the Kerala Registry of Epilepsy and Pregnancy.
Topics: Adult; Anticonvulsants; Carbamazepine; Female; Folic Acid; Humans; India; Lamotrigine; Levetiracetam; Oxcarbazepine; Phenytoin; Pregnancy; Pregnancy Complications; Registries; Seizures; Topiramate; Valproic Acid | 2020 |
Clinical correlates associated with the long-term response of bipolar disorder patients to lithium, valproate or lamotrigine: A retrospective study.
Topics: Adult; Alcoholism; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Comorbidity; Female; Follow-Up Studies; Humans; Lamotrigine; Lithium Compounds; Male; Middle Aged; Retrospective Studies; Seoul; Treatment Outcome; Valproic Acid | 2020 |
Valproate risk form-Surveying 215 clinicians involving 4775 encounters.
Topics: Adolescent; Adult; Anticonvulsants; Epilepsy; Female; Humans; Lamotrigine; Levetiracetam; Physicians; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Risk Assessment; Surveys and Questionnaires; United Kingdom; Valproic Acid | 2020 |
Effects of Sodium Valproate Combined with Lamotrigine on Quality of Life and Serum Inflammatory Factors in Patients with Poststroke Secondary Epilepsy.
Topics: Aged; Anticonvulsants; Biomarkers; Brain; Case-Control Studies; Down-Regulation; Drug Therapy, Combination; Epilepsy; Female; HMGB1 Protein; Humans; Inflammation Mediators; Interleukin-6; Lamotrigine; Male; Matrix Metalloproteinase 9; Middle Aged; Quality of Life; Stroke; Time Factors; Treatment Outcome; Valproic Acid | 2020 |
Delirium Secondary to Lamotrigine Toxicity.
Topics: Adolescent; Adult; Aged; Delirium; Drug Interactions; Female; Humans; Lamotrigine; Male; Middle Aged; Seizures; Sertraline; Valproic Acid | 2020 |
Neurocognition after prenatal levetiracetam, lamotrigine, carbamazepine or valproate exposure.
Topics: Anticonvulsants; Carbamazepine; Child; Child Development; Cognitive Dysfunction; Female; Humans; Lamotrigine; Levetiracetam; Netherlands; Neuropsychological Tests; Pregnancy; Prenatal Exposure Delayed Effects; Prospective Studies; Registries; Valproic Acid; Wechsler Scales | 2020 |
Testing association of rare genetic variants with resistance to three common antiseizure medications.
Topics: Anticonvulsants; Case-Control Studies; Drug Resistance; Epilepsy; Female; Genotype; Humans; Lamotrigine; Levetiracetam; Male; Pharmacogenomic Variants; Valproic Acid | 2020 |
Analysis of antiseizure drug-related adverse reactions from the electronic health record using the common data model.
Topics: Anticonvulsants; Common Data Elements; Drug-Related Side Effects and Adverse Reactions; Electronic Health Records; Epilepsy; Humans; Lamotrigine; Levetiracetam; Oxcarbazepine; Topiramate; Valproic Acid | 2020 |
Treatment of epilepsy in adults: Expert opinion in South Korea.
Topics: Adult; Aged; Anticonvulsants; Epilepsies, Partial; Epilepsy, Absence; Epilepsy, Generalized; Expert Testimony; Female; Humans; Lamotrigine; Levetiracetam; Male; Middle Aged; Oxcarbazepine; Republic of Korea; Surveys and Questionnaires; Treatment Outcome; Valproic Acid; Young Adult | 2020 |
Improvement of epilepsy with lacosamide in a patient with ring chromosome 20 syndrome.
Topics: Anticonvulsants; Carbamazepine; Child; Electroencephalography; Epilepsy; Humans; Lacosamide; Lamotrigine; Levetiracetam; Male; Ring Chromosomes; Seizures; Treatment Outcome; Valproic Acid | 2020 |
Pharmacoresponse in genetic generalized epilepsy: a genome-wide association study.
Topics: Adolescent; Anticonvulsants; Case-Control Studies; Child; Cohort Studies; Epilepsy, Generalized; Europe; Female; Genome-Wide Association Study; Humans; Lamotrigine; Levetiracetam; Male; Retrospective Studies; Treatment Outcome; Valproic Acid | 2020 |
Valproic Acid Impacts the Growth of Growth Plate Chondrocytes.
Topics: Animals; Anticonvulsants; Cells, Cultured; Child; Chondrocytes; Growth Plate; Humans; Lamotrigine; Rats; Valproic Acid | 2020 |
Sub-additive (antagonistic) interaction of lacosamide with lamotrigine and valproate in the maximal electroshock-induced seizure model in mice: an isobolographic analysis.
Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Drug Therapy, Combination; Electroshock; Epilepsy; Lacosamide; Lamotrigine; Male; Mice; Seizures; Valproic Acid | 2020 |
Dosing Recommendations Based on Population Pharmacokinetics of Lamotrigine in Mexican Adult Patients With Epilepsy.
Topics: Adult; Anticonvulsants; Epilepsy; Humans; Lamotrigine; Triazines; Valproic Acid | 2020 |
The clinical spectrum of familial and sporadic idiopathic generalized epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Epilepsy, Generalized; Female; Genetic Predisposition to Disease; Humans; Lamotrigine; Levetiracetam; Male; Middle Aged; Pedigree; Valproic Acid | 2020 |
Gaze-evoked nystagmus associated with valproic acid-induced lamotrigine toxicity.
Topics: Adult; Anticonvulsants; Epilepsy, Temporal Lobe; Female; Humans; Lamotrigine; Nystagmus, Pathologic; Seizures; Valproic Acid | 2020 |
Mood-Stabilizing Antiepileptic Treatment Response in Bipolar Disorder: A Genome-Wide Association Study.
Topics: Adult; Affect; Anticonvulsants; Antimanic Agents; Bipolar Disorder; Female; Gastrointestinal Absorption; Genome-Wide Association Study; Humans; Lamotrigine; Male; Middle Aged; Multidrug Resistance-Associated Proteins; Oxcarbazepine; Pharmacogenetics; Pharmacogenomic Variants; Polymorphism, Single Nucleotide; Quantitative Trait Loci; Retrospective Studies; Thrombospondins; Treatment Outcome; Valproic Acid | 2020 |
Antiseizure drug efficacy and tolerability in established and novel drug discovery seizure models in outbred vs inbred mice.
Topics: Animals; Animals, Outbred Strains; Anticonvulsants; Behavior, Animal; Brain; Carbamazepine; Cornea; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Discovery; Drug Evaluation, Preclinical; Drug Resistant Epilepsy; Electroshock; Kindling, Neurologic; Lamotrigine; Levetiracetam; Locomotion; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Open Field Test; Phenobarbital; Seizures; Treatment Outcome; Valproic Acid | 2020 |
Antiepileptic combination therapy with Stevens-Johnson syndrome and toxic epidermal necrolysis: Analysis of a Japanese pharmacovigilance database.
Topics: Anticonvulsants; Carbamazepine; Clobazam; Clonazepam; Databases, Factual; Drug Therapy, Combination; Epilepsy; Gabapentin; Humans; Japan; Lacosamide; Lamotrigine; Levetiracetam; Lorazepam; Pharmacovigilance; Phenytoin; Stevens-Johnson Syndrome; Valproic Acid | 2020 |
Patterns and prognostic markers for treatment response in generalized epilepsies.
Topics: Adolescent; Adult; Anticonvulsants; Biomarkers; Drug Resistance; Epilepsy, Generalized; Humans; Lamotrigine; Levetiracetam; Treatment Outcome; Valproic Acid; Young Adult | 2020 |
Trends of anti-seizure medication use in pediatric patients in six cities in China from 2013 to 2018.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; China; Epilepsy; Female; Humans; Infant; Lamotrigine; Levetiracetam; Male; Oxcarbazepine; Piracetam; Seizures; Valproic Acid | 2020 |
Antiseizure medication use during pregnancy and risk of ASD and ADHD in children.
Topics: Adolescent; Adult; Anticonvulsants; Attention Deficit Disorder with Hyperactivity; Autism Spectrum Disorder; Carbamazepine; Drug Prescriptions; Epilepsy; Female; Humans; Lamotrigine; Pregnancy; Prenatal Exposure Delayed Effects; Registries; Retrospective Studies; Self Report; Sweden; Valproic Acid | 2020 |
Association of Prenatal Exposure to Valproate and Other Antiepileptic Drugs With Intellectual Disability and Delayed Childhood Milestones.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clonazepam; Denmark; Developmental Disabilities; Drug Therapy, Combination; Epilepsy; Female; Humans; Infant; Intellectual Disability; Lamotrigine; Male; Oxcarbazepine; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Valproic Acid | 2020 |
Effects of valproate, lamotrigine, and levetiracetam monotherapy on bone health in newly diagnosed adult patients with epilepsy.
Topics: Adult; Anticonvulsants; Bone Density; Epilepsy; Humans; Lamotrigine; Levetiracetam; Triazines; Valproic Acid | 2020 |
An open study of valproate in subfertile men with epilepsy.
Topics: Adult; Anticonvulsants; Drug Substitution; Epilepsy; Female; Greece; Humans; Infertility, Male; Lamotrigine; Levetiracetam; Male; Pregnancy; Pregnancy Rate; Prospective Studies; Sperm Count; Sperm Motility; Spermatozoa; Valproic Acid | 2020 |
Risk factors of paradoxical reactions to anti-seizure medication in genetic generalized epilepsy.
Topics: Adult; Anticonvulsants; Epilepsy, Generalized; Humans; Lamotrigine; Levetiracetam; Myoclonic Epilepsy, Juvenile; Phenobarbital; Retrospective Studies; Risk Factors; Seizures; Valproic Acid; Zonisamide | 2021 |
Response to levetiracetam or lamotrigine in subjects with Juvenile Myoclonic Epilepsy previously treated with valproic acid: A single center retrospective study.
Topics: Anticonvulsants; Female; Humans; Lamotrigine; Levetiracetam; Myoclonic Epilepsy, Juvenile; Retrospective Studies; Treatment Outcome; Triazines; Valproic Acid | 2021 |
Modulation of the powder properties of lamotrigine by crystal forms.
Topics: Crystallography; Drug Compounding; Excipients; Lamotrigine; Microscopy, Electron, Scanning; Niacinamide; Particle Size; Porosity; Powders; Pressure; Rheology; Spectrum Analysis, Raman; Tablets; Valproic Acid; X-Ray Diffraction | 2021 |
Sodium valproate-induced cataract.
Topics: Anticonvulsants; Cataract; Humans; Lamotrigine; Valproic Acid | 2021 |
Knowledge of epilepsy among German pharmacists.
Topics: Anticonvulsants; Carbamazepine; Drug-Related Side Effects and Adverse Reactions; Epilepsy; Humans; Lamotrigine; Pharmacists; Seizures; Valproic Acid | 2021 |
Effects of antiepileptic drugs' administration during pregnancy on the nerve cell proliferation and axonal outgrowth of human neuroblastoma SH-SY5Y nerve cells.
Topics: Anticonvulsants; Carbamazepine; Cell Line, Tumor; Cell Proliferation; Child; Epilepsy; Female; Humans; Lamotrigine; NAV1.1 Voltage-Gated Sodium Channel; Neuroblastoma; Neuronal Outgrowth; Neurons; Phenytoin; Pregnancy; Prenatal Exposure Delayed Effects; Valproic Acid | 2021 |
Post-stroke epilepsy and antiepileptic drug use in men and women.
Topics: Adult; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Lamotrigine; Levetiracetam; Male; Medication Adherence; Middle Aged; Phenytoin; Stroke; Sweden; Valproic Acid | 2021 |
Effects of antiseizure medications on placental cells: Focus on heterodimeric placental carriers.
Topics: Anticonvulsants; Female; Humans; Lamotrigine; Levetiracetam; Placenta; Pregnancy; Valproic Acid | 2021 |
Antidepressant effect of repetitive transcranial magnetic stimulation is not impaired by intake of lithium or antiepileptic drugs.
Topics: Anticonvulsants; Antidepressive Agents; Antipsychotic Agents; Depression; Humans; Lamotrigine; Lithium; Transcranial Magnetic Stimulation; Treatment Outcome; Valproic Acid | 2021 |
Duration of untreated illness and bipolar disorder: time for a new definition? Results from a cross-sectional study.
Topics: Bipolar Disorder; Cross-Sectional Studies; Humans; Lamotrigine; Retrospective Studies; Valproic Acid | 2021 |
Changes in antiepileptic drug prescriptions over a decade in childbearing women in Lombardy region, Italy.
Topics: Anticonvulsants; Drug Prescriptions; Female; Humans; Infant; Lamotrigine; Levetiracetam; Male; Pregnancy; Valproic Acid | 2022 |
The Relationship Between Valproate and Lamotrigine/Levetiracetam Use and Prognosis in Patients With Epilepsy and Heart Failure: A Danish Register-Based Study.
Topics: Aged; Anticonvulsants; Cohort Studies; Denmark; Epilepsy; Heart Failure; Humans; Lamotrigine; Levetiracetam; Prognosis; Valproic Acid | 2022 |
[Women with epilepsy before and during pregnancy: a case series of outpatient counseling in a tertiary epilepsy center].
Topics: Anticonvulsants; Counseling; Epilepsy; Female; Folic Acid; Humans; Lamotrigine; Levetiracetam; Outpatients; Pregnancy; Pregnancy Complications; Retrospective Studies; Seizures; Valproic Acid | 2022 |
Plasma circulating cell-free mitochondrial DNA in depressive disorders.
Topics: Biomarkers; Cell-Free Nucleic Acids; DNA, Mitochondrial; Humans; Lamotrigine; Lithium; Mental Disorders; Valproic Acid | 2021 |
Evaluation of serum levels of asprosin and other metabolic profiles in patients with idiopathic tonic-clonic generalized epilepsy on treatment with valproic acid.
Topics: Adult; Anticonvulsants; Blood Glucose; Body Mass Index; Body Weights and Measures; Cross-Sectional Studies; Epilepsy, Tonic-Clonic; Female; Fibrillin-1; Glycated Hemoglobin; Humans; Insulin; Lamotrigine; Lipids; Male; Valproic Acid | 2022 |
Effects of Low- and High-Dose Valproic Acid and Lamotrigine on the Heart in Female Rats.
Topics: Animals; Anticonvulsants; Epilepsy; Female; Humans; Lamotrigine; Rats; Triazines; Valproic Acid | 2022 |
Changes in the use of antiseizure medications in children and adolescents in Norway, 2009-2018.
Topics: Adolescent; Adult; Anticonvulsants; Child; Epilepsy; Female; Humans; Lamotrigine; Levetiracetam; Valproic Acid | 2022 |
Antiseizure medication treatment pathways for US Medicare beneficiaries with newly treated epilepsy.
Topics: Aged; Anticonvulsants; Epilepsy; Gabapentin; Humans; Lacosamide; Lamotrigine; Levetiracetam; Medicare; Retrospective Studies; United States; Valproic Acid | 2022 |
Trends in antiseizure medication prescription patterns among all adults, women, and older adults with epilepsy: A German longitudinal analysis from 2008 to 2020.
Topics: Aged; Anticonvulsants; Benzodiazepines; Carbamazepine; Drug Prescriptions; Epilepsy; Epilepsy, Generalized; Female; Humans; Lamotrigine; Levetiracetam; Valproic Acid | 2022 |
Association of Lithium Treatment With the Risk of Osteoporosis in Patients With Bipolar Disorder.
Topics: Adult; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Female; Humans; Lamotrigine; Lithium; Lithium Compounds; Male; Middle Aged; Osteoporosis; Retrospective Studies; Valproic Acid | 2022 |
Comparison of Rates of Type 2 Diabetes in Adults and Children Treated With Anticonvulsant Mood Stabilizers.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Child; Cohort Studies; Diabetes Mellitus, Type 2; Female; Humans; Lamotrigine; Middle Aged; Oxcarbazepine; Valproic Acid; Young Adult | 2022 |
Response to lithium and anticonvulsants among patients with bipolar disorder with and without comorbid epilepsy - A nation-wide population-based longitudinal study.
Topics: Anticonvulsants; Antipsychotic Agents; Bipolar Disorder; Comorbidity; Epilepsy; Humans; Lamotrigine; Lithium; Longitudinal Studies; Valproic Acid | 2022 |
Trends in the prescription of anti-seizure medicines for pregnant women outpatients with epilepsy during 2016-2020 in Japan.
Topics: Anticonvulsants; Epilepsy; Female; Humans; Japan; Lamotrigine; Levetiracetam; Outpatients; Pregnancy; Pregnant Women; Prescriptions; Valproic Acid | 2022 |
Trends in the choice of antiseizure medications in juvenile myoclonic epilepsy: A retrospective multi-center study from Turkey between 2010 and 2020.
Topics: Adolescent; Anticonvulsants; Child; Female; Humans; Lamotrigine; Levetiracetam; Male; Myoclonic Epilepsy, Juvenile; Retrospective Studies; Seizures; Sex Factors; Treatment Outcome; Turkey; Valproic Acid | 2022 |
Association of Prenatal Exposure to Antiseizure Medication With Risk of Autism and Intellectual Disability.
Topics: Anticonvulsants; Autism Spectrum Disorder; Autistic Disorder; Carbamazepine; Child; Cohort Studies; Epilepsy; Female; Humans; Intellectual Disability; Lamotrigine; Levetiracetam; Male; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Topiramate; Valproic Acid | 2022 |
A description of sodium valproate, lamotrigine and levetiracetam consumption in the Western Cape public sector.
Topics: Anticonvulsants; Female; Humans; Lamotrigine; Levetiracetam; Public Sector; Retrospective Studies; Valproic Acid | 2022 |
Effects of treatment with clinically relevant valproate, carbamazepine, oxcarbazepine, topiramate, lamotrigine and levetiracetam on ovarian folliculogenesis in young rats.
Topics: Animals; Anticonvulsants; Benzodiazepines; Carbamazepine; Caspase 3; Caspase 9; Epidermal Growth Factor; Female; Lamotrigine; Levetiracetam; Ovary; Oxcarbazepine; Proliferating Cell Nuclear Antigen; Rats; Rats, Wistar; Topiramate; Valproic Acid | 2022 |
Risk factors of elevated blood ammonia level in epilepsy patients treated with lamotrigine.
Topics: Ammonia; Anticonvulsants; Epilepsy; Humans; Hyperammonemia; Lamotrigine; Risk Factors; Seizures; Triazines; Valproic Acid | 2022 |
Efficacy and safety of antiseizure medication in post-stroke epilepsy.
Topics: Anticonvulsants; Epilepsies, Partial; Epilepsy; Humans; Lacosamide; Lamotrigine; Levetiracetam; Seizures; Sodium Channels; Stroke; Valproic Acid | 2022 |
Pharmacotherapeutic management of seizures in patients with Angleman Syndrome.
Topics: Anticonvulsants; Cannabidiol; Child; Clobazam; Clonazepam; Ethosuximide; Humans; Lamotrigine; Levetiracetam; Quality of Life; Seizures; Topiramate; Valproic Acid | 2022 |
An Italian consensus on the management of Lennox-Gastaut syndrome.
Topics: Anticonvulsants; Cannabidiol; Clobazam; Consensus; Fenfluramine; Humans; Lamotrigine; Lennox Gastaut Syndrome; Quality of Life; Topiramate; Valproic Acid | 2022 |
Simultaneous determination of plasma lamotrigine, lamotrigine N2-glucuronide and lamotrigine N2-oxide by UHPLC-MS/MS in epileptic patients.
Topics: Anticonvulsants; Chromatography, High Pressure Liquid; Epilepsy; Glucuronides; Humans; Lamotrigine; Organic Chemicals; Oxides; Tandem Mass Spectrometry; Triazines; Valproic Acid | 2022 |
Lithium produces bi-directionally regulation of mood disturbance, acts synergistically with anti-depressive/-manic agents, and did not deteriorate the cognitive impairment in murine model of bipolar disorder.
Topics: Animals; Anticonvulsants; Antidepressive Agents; Antimanic Agents; Bipolar Disorder; Cognitive Dysfunction; Disease Models, Animal; Lamotrigine; Lithium; Mice; Valproic Acid | 2022 |
Real-world effectiveness of mood stabilizer use in schizophrenia.
Topics: Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Carbamazepine; Female; Humans; Lamotrigine; Lithium; Male; Schizophrenia; Valproic Acid | 2023 |
Effects of antiepileptic drugs polytherapy on pregnancy outcomes in women with epilepsy: An observation study in northwest China.
Topics: Anticonvulsants; Epilepsy; Female; Humans; Lamotrigine; Levetiracetam; Male; Phenobarbital; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Prenatal Exposure Delayed Effects; Registries; Topiramate; Valproic Acid | 2022 |
Prescribing changes for bipolar patients discharged from two public psychiatric hospitals in Taiwan, 2006-2019.
Topics: Anticonvulsants; Antidepressive Agents; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Carbamazepine; Hospitals, Psychiatric; Humans; Lamotrigine; Lithium; Patient Discharge; Retrospective Studies; Taiwan; Valproic Acid | 2022 |
Epilepsy and pregnancy. Factors associated with epileptic seizures during pregnancy.
Topics: Adult; Anticonvulsants; Epilepsy; Female; Humans; Lamotrigine; Levetiracetam; Pregnancy; Seizures; Valproic Acid | 2023 |
Multi-dimensional relationships among dementia, depression and prescribed drugs in England and Wales hospitals.
Topics: Aged; Anticonvulsants; Antidepressive Agents; Antipsychotic Agents; Depression; Donepezil; Dothiepin; Frontotemporal Dementia; Hospitals; Humans; Lamotrigine; Memantine; Mirtazapine; NAD; Sertraline; Valproic Acid; Venlafaxine Hydrochloride; Wales | 2022 |
Efficacy of antiseizure medication in a mouse model of HCN1 developmental and epileptic encephalopathy.
Topics: Animals; Anticonvulsants; Epilepsy; Epilepsy, Generalized; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Lamotrigine; Mice; Potassium Channels; Seizures; Valproic Acid | 2023 |
Prenatal Carbamazepine Exposure and Academic Performance in Adolescents: A Population-Based Cohort Study.
Topics: Academic Performance; Adolescent; Anticonvulsants; Benzodiazepines; Carbamazepine; Child; Cohort Studies; Female; Humans; Lamotrigine; Mothers; Pregnancy; Prenatal Exposure Delayed Effects; Valproic Acid | 2023 |
Comparative Safety of Antiseizure Medication Monotherapy for Major Malformations.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Benzodiazepines; Carbamazepine; Cohort Studies; Epilepsy; Female; Humans; Lamotrigine; Levetiracetam; Male; Oxcarbazepine; Pregnancy; Topiramate; Valproic Acid | 2023 |
New insight into the management of toxic epidermal necrolysis following the coadministration of lamotrigine and valproic acid.
Topics: Anticonvulsants; Humans; Lamotrigine; Stevens-Johnson Syndrome; Triazines; Valproic Acid | 2023 |
Trends in antiseizure medications utilization among women of childbearing age with epilepsy in Poland between 2015 and 2019.
Topics: Anticonvulsants; Benzodiazepines; Carbamazepine; Epilepsy; Female; Humans; Lamotrigine; Levetiracetam; Male; Oxcarbazepine; Poland; Topiramate; Valproic Acid | 2023 |
Pharmacological treatment of bipolar disorder and risk of diabetes mellitus: A nationwide study of 30,451 patients.
Topics: Anticonvulsants; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Diabetes Mellitus; Humans; Lamotrigine; Lithium; Valproic Acid | 2023 |
Effects of dosage in new users of lamotrigine inducing epidermal necrolysis: Results of the German Registry of Severe Skin Reactions.
Topics: Adult; Anticonvulsants; Epilepsy; Female; Humans; Lamotrigine; Male; Registries; Stevens-Johnson Syndrome; Triazines; Valproic Acid | 2023 |
Liquid chromatography coupled with tandem mass spectrometry for simultaneous quantification of valproate, valproate-glucuronide and lamotrigine in various biological matrices of rat.
Topics: Animals; Chromatography, High Pressure Liquid; Glucuronides; Lamotrigine; Rats; Tandem Mass Spectrometry; Valproic Acid | 2023 |
Prenatal Exposure to Antiseizure Medication and Incidence of Childhood- and Adolescence-Onset Psychiatric Disorders.
Topics: Adolescent; Anticonvulsants; Attention Deficit Disorder with Hyperactivity; Carbamazepine; Child; Child, Preschool; Epilepsy; Female; Humans; Incidence; Lamotrigine; Levetiracetam; Male; Oxcarbazepine; Pregnancy; Prenatal Exposure Delayed Effects; Prospective Studies; Topiramate; Valproic Acid | 2023 |
Selection and Continuation of Antiseizure Medication in Children With Epilepsy in Sweden From 2007 to 2020.
Topics: Anticonvulsants; Child; Child, Preschool; Epilepsy; Female; Humans; Infant; Lamotrigine; Levetiracetam; Male; Oxcarbazepine; Sweden; Triazines; Valproic Acid | 2023 |
Prescribing Trends of Antiseizure Drugs in Women Veterans With Epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Epilepsy; Female; Gabapentin; Humans; Lamotrigine; Levetiracetam; Middle Aged; Pain; Pharmaceutical Preparations; Teratogenesis; Topiramate; Valproic Acid; Veterans; Young Adult | 2023 |
Bearing variant alleles at uridine glucuronosyltransferase polymorphisms UGT2B7 -161C > T (rs7668258) or UGT1A4*3 c.142 T > G (rs2011425) has no relevant consequences for lamotrigine troughs in adults with epilepsy.
Topics: Adult; Alleles; Anticonvulsants; Bayes Theorem; Epilepsy; Genotype; Glucuronosyltransferase; Humans; Lamotrigine; Polymorphism, Single Nucleotide; UDP-Glucuronosyltransferase 1A9; Valproic Acid | 2023 |
Birth outcomes in pregnant women with epilepsy: A Nationwide multicenter study from Türkiye.
Topics: Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Infant; Infant, Newborn; Lamotrigine; Pregnancy; Pregnancy Complications; Pregnant Women; Prospective Studies; Valproic Acid | 2023 |
Utilization of Antiseizure Medications in Women of Childbearing Age With Epilepsy and Nonepilepsy Indications: A Retrospective Cohort Study.
Topics: Anticonvulsants; Clonazepam; Diazepam; Epilepsy; Female; Gabapentin; Humans; Lamotrigine; Lorazepam; Retrospective Studies; Topiramate; Valproic Acid | 2023 |
Changes over 24 years in a pregnancy register - Teratogenicity and epileptic seizure control.
Topics: Anticonvulsants; Australia; Epilepsy; Female; Humans; Lamotrigine; Pregnancy; Pregnancy Complications; Seizures; Valproic Acid | 2023 |