valproic acid has been researched along with ketamine in 27 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.70) | 18.7374 |
| 1990's | 2 (7.41) | 18.2507 |
| 2000's | 5 (18.52) | 29.6817 |
| 2010's | 15 (55.56) | 24.3611 |
| 2020's | 4 (14.81) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Anavekar, SN; Davis, HT; Tsianco, MC; Wardell, WM | 1 |
| Lloyd, KG; Naquet, R; Valin, A; Voltz, C | 1 |
| Löscher, W; Rohlfs, A; Rundfeldt, C | 1 |
| Lerner, AJ; Maddux, BN; Sagar, SM; Suarez, JI; Ubogu, EE; Werz, MA | 1 |
| Brody, SA; Geyer, MA; Large, CH; Ong, JC | 1 |
| Chen, LC; Furuya, H; Hashimoto, Y; Hiraoka, K; Kubota, T; Takekawa, K | 1 |
| Brutsche, NE; Diazgranados, N; Ibrahim, L; Kammerer, WA; Khalife, S; Kronstein, P; Luckenbaugh, DA; Machado-Vieira, R; Manji, HK; Newberg, A; Quezado, Z; Salvadore, G; Zarate, CA | 1 |
| Gulati, S; Lodha, R; Raj, D | 1 |
| Brutsche, N; Cassarly, C; Franco-Chaves, J; Ibrahim, L; Luckenbaugh, DA; Marquardt, CA; Mathews, D; Zarate, CA | 1 |
| Budni, J; Dal-Pizzol, F; Deroza, PF; Fraga, Dde B; Ghedim, FV; Oliveira, MB; Quevedo, J; Steckert, AV; Valvassori, SS; Zugno, AI | 1 |
| Barbas, C; Laje, G; Lorenzo, MP; Ramamoorthy, A; Silva dos Santos, M; Villaseñor, A; Wainer, IW; Zarate, C | 1 |
| Ionescu, DF; Luckenbaugh, DA; Niciu, MJ; Richards, EM; Zarate, CA | 1 |
| Bregy, L; Brown, SA; Dallmann, R; Detmar, M; Hollmén, M; Kohler, M; Li, X; Martinez-Lozano Sinues, P; Proulx, S; Zenobi, R | 1 |
| Ballard, ED; Brutsche, NE; Ionescu, DF; Luckenbaugh, DA; Lundin, NB; Machado-Vieira, R; Niciu, MJ; Richards, EM; Vande Voort, JL; Xu, AJ; Zarate, CA | 1 |
| Brigo, F; Höfler, J; Kalss, G; Leitinger, M; Rohracher, A; Trinka, E | 1 |
| Baldwin, R; Lumley, L; Niquet, J; Norman, K; Suchomelova, L; Wasterlain, CG | 1 |
| Luckenbaugh, DA; Niciu, MJ; Pennybaker, SJ; Zarate, CA | 1 |
| Ambrosi, M; Pavone, P; Striano, P; Verrotti, A | 1 |
| Baldwin, R; Estrada, IBF; Furtado, MA; Lumley, L; Naylor, D; Niquet, J; Rossetti, F; Schultz, M; Suchomelova, L; Wasterlain, CG | 1 |
| Baranes, S; Chapman, S; David, T; Dekel Jaoui, H; Efrati, R; Egoz, I; Gez, R; Gore, A; Grauer, E; Lazar, S; Neufeld-Cohen, A; Yampolsky, M | 1 |
| García-Peñas, JJ; González-Alguacil, E; Soto-Insuga, V | 1 |
| Brisca, G; Buratti, S; Giacheri, E; Mancardi, MM; Moscatelli, A; Nobili, L; Palmieri, A; Riva, A; Striano, P; Tibaldi, J | 1 |
7 review(s) available for valproic acid and ketamine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Pharmacologic treatment of status epilepticus.
Topics: Anticonvulsants; Benzodiazepines; Humans; Ketamine; Levetiracetam; Piracetam; Randomized Controlled Trials as Topic; Seizures; Status Epilepticus; Treatment Failure; Valproic Acid | 2016 |
Symptomatology and predictors of antidepressant efficacy in extended responders to a single ketamine infusion.
Topics: Adult; Alcohol-Related Disorders; Antidepressive Agents; Bipolar Disorder; Depressive Disorder, Major; Female; Humans; Infusions, Intravenous; Ketamine; Lithium; Male; Middle Aged; Psychiatric Status Rating Scales; Treatment Outcome; Valproic Acid | 2017 |
Pediatric status epilepticus: improved management with new drug therapies?
Topics: Algorithms; Anticonvulsants; Child; Clinical Protocols; Humans; Ketamine; Levetiracetam; Midazolam; Piracetam; Prospective Studies; Retrospective Studies; Status Epilepticus; Valproic Acid | 2017 |
Rational polytherapy in the treatment of cholinergic seizures.
Topics: Animals; Anticonvulsants; Cholinesterase Inhibitors; Drug Therapy, Combination; Ketamine; Male; Midazolam; Muscarinic Agonists; Nerve Agents; Pilocarpine; Rats; Rats, Sprague-Dawley; Soman; Status Epilepticus; Valproic Acid | 2020 |
[Paediatric status epilepticus].
Topics: Adult; Anesthetics; Anticonvulsants; Benzodiazepines; Child; Epilepsy; Humans; Ketamine; Lacosamide; Levetiracetam; Lidocaine; Phenobarbital; Phenytoin; Propofol; Seizures; Status Epilepticus; Topiramate; Valproic Acid | 2022 |
Ketamine as advanced second-line treatment in benzodiazepine-refractory convulsive status epilepticus in children.
Topics: Animals; Anticonvulsants; Benzodiazepines; Drug Resistant Epilepsy; Ketamine; Status Epilepticus; Valproic Acid | 2023 |
4 trial(s) available for valproic acid and ketamine
| Article | Year |
|---|---|
A randomized add-on trial of an N-methyl-D-aspartate antagonist in treatment-resistant bipolar depression.
Topics: Adolescent; Adult; Aged; Bipolar Disorder; Diagnostic and Statistical Manual of Mental Disorders; Double-Blind Method; Drug Resistance; Drug Therapy, Combination; Excitatory Amino Acid Antagonists; Female; Humans; Ketamine; Lithium Compounds; Male; Middle Aged; N-Methylaspartate; Placebos; Psychiatric Status Rating Scales; Treatment Outcome; Valproic Acid | 2010 |
A pilot study of plasma metabolomic patterns from patients treated with ketamine for bipolar depression: evidence for a response-related difference in mitochondrial networks.
Topics: Adult; Antidepressive Agents; Biomarkers, Pharmacological; Bipolar Disorder; Cross-Over Studies; Depressive Disorder, Treatment-Resistant; Drug Therapy, Combination; Female; Humans; Ketamine; Lithium; Lysophosphatidylcholines; Lysophospholipids; Male; Metabolome; Middle Aged; Pilot Projects; Valproic Acid; Young Adult | 2014 |
A single infusion of ketamine improves depression scores in patients with anxious bipolar depression.
Topics: Adult; Affect; Anxiety; Anxiety Disorders; Bipolar Disorder; Cross-Over Studies; Depression; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Infusions, Intravenous; Ketamine; Lithium Carbonate; Male; Middle Aged; Valproic Acid | 2015 |
Lithium and Valproate Levels Do Not Correlate with Ketamine's Antidepressant Efficacy in Treatment-Resistant Bipolar Depression.
Topics: Adult; Antidepressive Agents; Bipolar Disorder; Cross-Over Studies; Depressive Disorder, Treatment-Resistant; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Ketamine; Lithium; Male; Middle Aged; Psychiatric Status Rating Scales; Treatment Outcome; Valproic Acid | 2015 |
16 other study(ies) available for valproic acid and ketamine
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Postmarketing surveillance of new drugs: II. Case studies.
Topics: Azauridine; Bacteriuria; Contraceptives, Oral; Costs and Cost Analysis; Double-Blind Method; Drug-Related Side Effects and Adverse Reactions; Humans; Ketamine; Levodopa; Research Design; United States; United States Food and Drug Administration; Valproic Acid | 1979 |
Effects of pharmacological manipulation on neurotransmitter and other amino acid levels in the CSF of the Senegalese baboon Papio papio.
Topics: Amino Acids; Animals; Diazepam; Dizocilpine Maleate; Electroshock; Hemolysis; Humans; Ketamine; Neurotransmitter Agents; Papio; Phencyclidine; Reference Values; Valproic Acid | 1991 |
Reduction in firing rate of substantia nigra pars reticulata neurons by valproate: influence of different types of anesthesia in rats.
Topics: Anesthetics; Animals; Blood Pressure; Female; Heart Rate; Ketamine; Membrane Potentials; Rats; Rats, Wistar; Sodium Chloride; Substantia Nigra; Time Factors; Valproic Acid | 1995 |
Ketamine for refractory status epilepticus: a case of possible ketamine-induced neurotoxicity.
Topics: Adult; Anticonvulsants; Atrophy; Brain; Electroencephalography; Excitatory Amino Acid Antagonists; Humans; Ketamine; Lorazepam; Magnetic Resonance Imaging; Male; Neurotoxicity Syndromes; Phenytoin; Receptors, N-Methyl-D-Aspartate; Severity of Illness Index; Status Epilepticus; Valproic Acid | 2003 |
An investigation of the efficacy of mood stabilizers in rodent models of prepulse inhibition.
Topics: Amphetamine; Anesthetics, Dissociative; Animals; Antimanic Agents; Carbamazepine; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Drug Interactions; Ketamine; Lithium; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Phenytoin; Reflex, Startle; Valproic Acid | 2005 |
Rapid detection of drugs in biofluids using atmospheric pressure chemi/chemical ionization mass spectrometry.
Topics: Amphetamines; Atmospheric Pressure; Humans; Ions; Ketamine; Mass Spectrometry; Models, Chemical; Reference Standards; Sensitivity and Specificity; Substance Abuse Detection; Valproic Acid; Volatile Organic Compounds | 2009 |
Status epilepticus.
Topics: Anticonvulsants; Benzodiazepines; Child; Clinical Protocols; Fructose; GABA Modulators; Humans; Ketamine; Levetiracetam; Midazolam; Pentobarbital; Phenobarbital; Phenytoin; Piracetam; Propofol; Status Epilepticus; Thiopental; Topiramate; Valproic Acid | 2011 |
Family history of alcohol dependence and antidepressant response to an N-methyl-D-aspartate antagonist in bipolar depression.
Topics: Adult; Alcoholism; Antidepressive Agents; Bipolar Disorder; Cross-Over Studies; Double-Blind Method; Excitatory Amino Acid Antagonists; Female; Humans; Infusions, Intravenous; Ketamine; Linear Models; Male; Middle Aged; Personality Inventory; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Treatment Outcome; Valproic Acid | 2012 |
Evaluation of behavioral and neurochemical changes induced by ketamine in rats: implications as an animal model of mania.
Topics: Animals; Antimanic Agents; Behavior, Animal; Bipolar Disorder; Disease Models, Animal; Drug Interactions; Ketamine; Lithium; Male; Protein Carbonylation; Rats; Rats, Wistar; Valproic Acid | 2012 |
Drug Pharmacokinetics Determined by Real-Time Analysis of Mouse Breath.
Topics: Administration, Oral; Analgesics; Anesthetics, Intravenous; Animals; Anticonvulsants; Breath Tests; Equipment Design; Injections, Intraperitoneal; Ketamine; Mice; Propofol; Spectrometry, Mass, Electrospray Ionization; Valproic Acid | 2015 |
Midazolam-ketamine dual therapy stops cholinergic status epilepticus and reduces Morris water maze deficits.
Topics: Animals; Anticonvulsants; Brain; Cholinergic Agents; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Ketamine; Learning Disabilities; Lithium Chloride; Male; Maze Learning; Midazolam; N-Methylscopolamine; Pilocarpine; Rats; Rats, Sprague-Dawley; Status Epilepticus; Valproic Acid | 2016 |
Neuroprotection by delayed triple therapy following sarin nerve agent insult in the rat.
Topics: Animals; Anticonvulsants; Behavior, Animal; Brain; Carrier Proteins; Dinoprostone; Disease Models, Animal; Drug Administration Schedule; Drug Therapy, Combination; Injections, Intramuscular; Injections, Intraperitoneal; Ketamine; Male; Midazolam; Open Field Test; Rats, Sprague-Dawley; Receptors, GABA-A; Recognition, Psychology; Sarin; Status Epilepticus; Time Factors; Valproic Acid | 2021 |