valproic acid has been researched along with kainic acid in 30 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (30.00) | 18.7374 |
| 1990's | 4 (13.33) | 18.2507 |
| 2000's | 6 (20.00) | 29.6817 |
| 2010's | 9 (30.00) | 24.3611 |
| 2020's | 2 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Bennett, JP; Coyle, JT; Schwarcz, R | 1 |
| Hansson, E; Nilsson, M; Rönnbäck, L | 1 |
| Maheshwari, MC; Selvamurthy, W; Sharma, SK; Singh, TP | 1 |
| Bossut, D; Frenk, H; Mayer, DJ | 1 |
| Kubová, H; Mares, P; Ortová, M; Velísek, L; Velísková, J | 1 |
| Anfosso, R; Calò, M; De Sarro, GB; Marmo, E; Nisticò, G; Rotiroti, D | 1 |
| Gale, K; Iadarola, MJ | 1 |
| Isaacson, RL; Lanthorn, TH | 1 |
| Czuczwar, SJ; Kleinrok, Z; Turski, L; Turski, W | 1 |
| Fuller, TA; Olney, JW | 1 |
| Clifford, DB; Dodson, WE; Ferrendelli, JA; Lothman, EW | 1 |
| Bolanos, AR; Helmers, SL; Holmes, GL; Hori, A; Mikati, M; Sarkisian, M; Stafstrom, CE; Tandon, P; Yang, Y | 1 |
| Czuczwar, SJ; Haberek, G; Kleinrok, Z; Matyska, J; Pilip, S; Tomczyk, T; Turski, WA; Urbanska, EM | 1 |
| Arkhipov, VI; Shevchenko, NA | 1 |
| Angehagen, M; Ben-Menachem, E; Hansson, E; Rönnbäck, L | 1 |
| Gobbi, G; Janiri, L | 1 |
| Khan, FA; Lian, XY; Stringer, JL | 1 |
| Han, X; Nedergaard, M; Oberheim, NA; Peng, W; Ransom, B; Takano, T; Tian, GF | 1 |
| Haastert, K; Jahn, K; Kotsiari, A; Krampfl, K; Petri, S; Ragancokova, D; Schlesinger, F; Stangel, M | 1 |
| Eisenach, JC; Hayashida, K; Hobo, S | 1 |
| Antonucci, F; Bozzi, Y; Braida, D; Caleo, M; Clerici, M; Corradini, I; De Astis, S; Donzelli, A; Frassoni, C; Inverardi, F; Lipp, HP; Loos, M; Martucci, R; Matteoli, M; Pattini, L; Sala, M; Verderio, C; Welzl, H; Wolfer, D | 1 |
| Chang, P; Walker, MC; Williams, RS | 1 |
| Bhowmik, M; Saini, N; Vohora, D | 1 |
| Bankstahl, M; Klein, S; Löscher, W | 1 |
| Greene, DL; Hoshi, N; Kang, S; Kay, HY; Kosenko, A | 1 |
| Tang, R; Tang, X; Yang, X; Yu, H | 1 |
| Ji, Y; Jiang, N; Kuang, P; Lao, W; Lin, W; Wang, Z; Yin, T; Zhao, Y; Zhu, H | 1 |
| Baharvand, H; Ghasemi-Kasman, M; Javan, M | 1 |
| Kandeda, AK; Mabou, ST; Nodeina, S | 1 |
| Li, J; Sha, L; Xu, Q | 1 |
1 review(s) available for valproic acid and kainic acid
| Article | Year |
|---|---|
Cellular compartments of GABA in brain and their relationship to anticonvulsant activity.
Topics: 4-Aminobutyrate Transaminase; Aminocaproates; Aminooxyacetic Acid; Animals; Anticonvulsants; Brain; Corpus Striatum; Denervation; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Kainic Acid; Kinetics; Mesencephalon; Muscimol; Neuroglia; Neurons; Rats; Receptors, Cell Surface; Receptors, GABA-A; Seizures; Substantia Nigra; Tissue Distribution; Valproic Acid; Vigabatrin | 1981 |
29 other study(ies) available for valproic acid and kainic acid
| Article | Year |
|---|---|
Inhibitors of GABA metabolism: implications for Huntington's disease.
Topics: 4-Aminobutyrate Transaminase; Alkynes; Aminocaproates; Aminocaproic Acid; Animals; Caudate Nucleus; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Huntington Disease; Kainic Acid; Male; Nerve Degeneration; Rats; Substantia Nigra; Transaminases; Valproic Acid | 1977 |
Receptor-coupled uptake of valproate in rat astroglial primary cultures.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Astrocytes; Biological Transport; Cells, Cultured; Cerebral Cortex; Clonidine; Drug Interactions; Glutamates; Glutamic Acid; Isoproterenol; Kainic Acid; Ketanserin; Phenylephrine; Prazosin; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Serotonin; Valproic Acid; Yohimbine | 1992 |
Kainic acid induced epileptogenesis in developing normal & undernourished rats--a computerised EEG analysis.
Topics: Age Factors; Animals; Cerebellum; Electroencephalography; Glycine; Hippocampus; Kainic Acid; Nutrition Disorders; Rats; Seizures; Spinal Cord; Valproic Acid | 1990 |
Is substance P a primary afferent neurotransmitter for nociceptive input? III. Valproic acid and chlordiazepoxide decrease behaviors elicited by intrathecal injection of substance P and excitatory compounds.
Topics: Animals; Anticonvulsants; Chlordiazepoxide; Injections, Spinal; Kainic Acid; Male; Morphine; Nociceptors; Pain; Rats; Rats, Inbred Strains; Spinal Cord; Strychnine; Substance P; Valproic Acid | 1988 |
Influence of clonazepam and valproate on kainate-induced model of psychomotor seizures.
Topics: Animals; Anticonvulsants; Clonazepam; Kainic Acid; Rats; Seizures; Valproic Acid | 1989 |
Convulsant effects of kainic acid and dihydrofolate are antagonized by sodium valproate.
Topics: Animals; Convulsants; Folic Acid; Folic Acid Antagonists; Kainic Acid; Pyrrolidines; Rats; Rats, Inbred Strains; Valproic Acid | 1983 |
Hippocampal involvement in the pharmacologic induction of withdrawal-like behaviors.
Topics: Animals; Cyclazocine; Endorphins; Enkephalin, Methionine; Enkephalins; Escape Reaction; Ethylketocyclazocine; Hippocampus; Humans; Injections, Intraventricular; Kainic Acid; Morphine Dependence; Pyrrolidines; Rats; Serotonin; Shivering; Substance Withdrawal Syndrome; Valproic Acid | 1981 |
Effects of some antiepileptic drugs in pentetrazol-induced convulsions in mice lesioned with kainic acid.
Topics: Acetazolamide; Animals; Anticonvulsants; Carbamazepine; Diazepam; Dose-Response Relationship, Drug; Hippocampus; Injections, Intraventricular; Kainic Acid; Male; Mice; Pentylenetetrazole; Phenobarbital; Pyrrolidines; Seizures; Succinimides; Trimethadione; Valproic Acid | 1981 |
Only certain anticonvulsants protect against kainate neurotoxicity.
Topics: Animals; Anticonvulsants; Diazepam; Kainic Acid; Male; Nervous System Diseases; Phenobarbital; Phenytoin; Pyrrolidines; Rats; Rats, Inbred Strains; Seizures; Valproic Acid | 1981 |
Effect of anticonvulsant drugs on kainic acid-induced epileptiform activity.
Topics: Animals; Anticonvulsants; Diazepam; Electroencephalography; Ethosuximide; Guinea Pigs; Hippocampus; Kainic Acid; Phenobarbital; Phenytoin; Pyrrolidines; Rats; Rats, Inbred Strains; Seizures; Valproic Acid | 1982 |
Comparison of valproate and phenobarbital treatment after status epilepticus in rats.
Topics: Animals; Anticonvulsants; Behavior, Animal; Disease Models, Animal; Excitatory Amino Acid Agonists; Hippocampus; Kainic Acid; Male; Maze Learning; Phenobarbital; Rats; Rats, Sprague-Dawley; Status Epilepticus; Stress, Physiological; Valproic Acid | 1998 |
NMDA- but not kainate-mediated events reduce efficacy of some antiepileptic drugs against generalized tonic-clonic seizures in mice.
Topics: Animals; Anticonvulsants; Carbamazepine; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Electroshock; Epilepsy, Tonic-Clonic; Kainic Acid; Male; Mice; N-Methylaspartate; Phenobarbital; Phenytoin; Receptors, N-Methyl-D-Aspartate; Valproic Acid | 1999 |
Extinction of operant behavior as the test for cognitive disorders induced with kainic acid.
Topics: Animals; Anticonvulsants; Cognition Disorders; Conditioning, Operant; Extinction, Psychological; Kainic Acid; Male; Rats; Rats, Wistar; Valproic Acid | 2002 |
Topiramate protects against glutamate- and kainate-induced neurotoxicity in primary neuronal-astroglial cultures.
Topics: Animals; Animals, Newborn; Anticonvulsants; Astrocytes; Calcium; Calcium Signaling; Cell Membrane; Cell Survival; Cells, Cultured; Fructose; Glutamic Acid; Immunohistochemistry; Kainic Acid; Nerve Degeneration; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Neurotoxicity Syndromes; Phenytoin; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; Topiramate; Valproic Acid | 2003 |
Sodium- and magnesium-valproate in vivo modulate glutamatergic and GABAergic synapses in the medial prefrontal cortex.
Topics: Action Potentials; Animals; Anticonvulsants; gamma-Aminobutyric Acid; Glutamic Acid; Kainic Acid; Magnesium; N-Methylaspartate; Prefrontal Cortex; Quisqualic Acid; Rats; Rats, Wistar; Salts; Sodium; Synapses; Valproic Acid | 2006 |
Fructose-1,6-bisphosphate has anticonvulsant activity in models of acute seizures in adult rats.
Topics: Acute Disease; Allylamine; Analysis of Variance; Animals; Anticonvulsants; Behavior, Animal; Deoxyglucose; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Fructosediphosphates; Kainic Acid; Male; Meperidine; Models, Chemical; Pilocarpine; Rats; Rats, Sprague-Dawley; Seizures; Valproic Acid | 2007 |
Loss of astrocytic domain organization in the epileptic brain.
Topics: Amino Acids; Amyloid beta-Protein Precursor; Animals; Anticonvulsants; Astrocytes; Basic Helix-Loop-Helix Transcription Factors; Behavior, Animal; Brain; Dendrites; Disease Models, Animal; Electroencephalography; Epilepsy; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Kainic Acid; Luminescent Proteins; Mice; Mice, Transgenic; Nerve Tissue Proteins; Neurons; Time Factors; Valproic Acid | 2008 |
Analysis of neuroprotective effects of valproic acid on primary motor neurons in monoculture or co-cultures with astrocytes or Schwann cells.
Topics: Animals; Astrocytes; Calcium Signaling; Cell Death; Cells, Cultured; Coculture Techniques; Fura-2; Immunohistochemistry; Kainic Acid; Motor Neurons; Neuroprotective Agents; Neurotoxins; Rats; Schwann Cells; Valproic Acid | 2009 |
Up-regulation of spinal glutamate transporters contributes to anti-hypersensitive effects of valproate in rats after peripheral nerve injury.
Topics: Analgesics; Animals; Disease Models, Animal; Drug Therapy, Combination; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Hyperalgesia; Kainic Acid; Pain Threshold; Peripheral Nerve Injuries; Rats; Rats, Sprague-Dawley; Riluzole; Spinal Cord; Up-Regulation; Valproic Acid | 2011 |
Epileptiform activity and cognitive deficits in SNAP-25(+/-) mice are normalized by antiepileptic drugs.
Topics: Animals; Anticonvulsants; Association Learning; Brain; Carbamazepine; Cognition Disorders; Epilepsy; Ethosuximide; Hyperkinesis; Kainic Acid; Male; Memory Disorders; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurons; Nimodipine; Seizures; Synaptosomal-Associated Protein 25; Valproic Acid | 2014 |
Seizure-induced reduction in PIP3 levels contributes to seizure-activity and is rescued by valproic acid.
Topics: Animals; Anticonvulsants; Cells, Cultured; GABA Antagonists; Hippocampus; Kainic Acid; Male; Neurons; Pentylenetetrazole; Phosphatidylinositol Phosphates; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Status Epilepticus; Valproic Acid | 2014 |
Histamine H3 receptor antagonism by ABT-239 attenuates kainic acid induced excitotoxicity in mice.
Topics: Animals; Anticonvulsants; Benzofurans; Dose-Response Relationship, Drug; Drug Therapy, Combination; Gene Expression; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hippocampus; Histamine H3 Antagonists; Kainic Acid; Male; Mice; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Protein Kinase Inhibitors; Pyrrolidines; Random Allocation; Seizures; Thiadiazoles; Valproic Acid | 2014 |
Inter-individual variation in the effect of antiepileptic drugs in the intrahippocampal kainate model of mesial temporal lobe epilepsy in mice.
Topics: Animals; Anticonvulsants; Carbamazepine; Diazepam; Disease Models, Animal; Drug Resistance; Electrodes, Implanted; Electroencephalography; Epilepsy, Temporal Lobe; Female; Hippocampus; Kainic Acid; Levetiracetam; Mice; Phenobarbital; Phenytoin; Piracetam; Seizures; Valproic Acid | 2015 |
M-current preservation contributes to anticonvulsant effects of valproic acid.
Topics: A Kinase Anchor Proteins; Action Potentials; Animals; Anthracenes; Anticonvulsants; Carbamates; Cells, Cultured; Drug Interactions; Female; Hippocampus; Humans; Kainic Acid; KCNQ2 Potassium Channel; Lipoylation; Male; Mice; Mice, Inbred C57BL; Muscarinic Agonists; Muscarinic Antagonists; Neurons; Phenylenediamines; Phosphorylation; Potassium Channel Blockers; Protein Processing, Post-Translational; Rats; Receptor, Muscarinic M1; Recombinant Fusion Proteins; Seizures; Signal Transduction; Superior Cervical Ganglion; Valproic Acid | 2015 |
Effects of spontaneous recurrent seizures on cognitive function via modulation of SNAREs expression.
Topics: Animals; Anticonvulsants; Cognition Disorders; Disease Models, Animal; Escape Reaction; Excitatory Amino Acid Agonists; Gene Expression Regulation; Hippocampus; Kainic Acid; Locomotion; Male; Maze Learning; Rats; Rats, Sprague-Dawley; Seizures; SNARE Proteins; Synapses; Synaptosomal-Associated Protein 25; Synaptotagmin I; Valproic Acid; Vesicle-Associated Membrane Protein 2 | 2018 |
Anticonvulsant effect of gentamicin on the seizures induced by kainic acid.
Topics: Analysis of Variance; Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy, Temporal Lobe; Excitatory Amino Acid Agonists; Gentamicins; Hippocampus; Injections, Intraperitoneal; Kainic Acid; Male; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Valproic Acid | 2018 |
Enhanced neurogenesis in degenerated hippocampi following pretreatment with miR-302/367 expressing lentiviral vector in mice.
Topics: Animals; Hippocampus; Kainic Acid; Lentivirus; Male; Mice; Mice, Inbred C57BL; MicroRNAs; Neurodegenerative Diseases; Neurogenesis; Neurons; Valproic Acid | 2017 |
An aqueous extract of Syzygium cumini protects against kainate-induced status epilepticus and amnesia: evidence for antioxidant and anti-inflammatory intervention.
Topics: Amnesia; Animals; Anti-Inflammatory Agents; Anticonvulsants; Antioxidants; Kainic Acid; Mice; Piracetam; Plant Extracts; Status Epilepticus; Syzygium; Valproic Acid | 2022 |
Long-term outcomes of classic and novel anti-seizure medication in a kainate-induced model of chronic epilepsy.
Topics: Animals; Anticonvulsants; Carbamazepine; Epilepsy; Epilepsy, Temporal Lobe; Kainic Acid; Mice; Valproic Acid | 2023 |