valproic acid and isotretinoin

valproic acid has been researched along with isotretinoin in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19901 (7.14)18.7374
1990's3 (21.43)18.2507
2000's4 (28.57)29.6817
2010's6 (42.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Holtzman, NA; Khoury, MJ1
Andersson, A; Berggren-Söderlund, M; Fex, G; Larsson, K1
Johnson, EM1
Cott, AD; Wisner, KL1
Hallman, H; Honkanen, T; Juvonen, E; Kauppila, M; Koistinen, P; Kutila, A; Mikkola, M; Nyländen, P; Poikonen, E; Rauhala, A; Savolainen, ER; Siitonen, T; Sinisalo, M; Suominen, M; Terävä, V; Timonen, T1
Lerche, CM; Philipsen, PA; Sehested, M; Wulf, HC1
Asz-Sigall, D; Guzmán-Sánchez, D1

Reviews

3 review(s) available for valproic acid and isotretinoin

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Alopecias due to drugs and other skin and systemic disorders.
    Current problems in dermatology, 2015, Volume: 47

    Topics: Alopecia; Anticonvulsants; Antidepressive Agents; Antineoplastic Agents; Dermatologic Agents; Dermatomycoses; Diet; Folliculitis; Herpes Zoster; HIV Infections; Humans; Isotretinoin; Lamotrigine; Lithium Compounds; Lupus Erythematosus, Systemic; Malnutrition; Mycosis Fungoides; Paroxetine; Sarcoidosis; Seasons; Skin Neoplasms; Starvation; Stress, Psychological; Syphilis; Triazines; Valproic Acid

2015

Trials

1 trial(s) available for valproic acid and isotretinoin

ArticleYear
Valproic acid combined with 13-cis retinoic acid and 1,25-dihydroxyvitamin D3 in the treatment of patients with myelodysplastic syndromes.
    Haematologica, 2007, Volume: 92, Issue:8

    Topics: Acetylation; Aged; Aged, 80 and over; Calcitriol; Cheilitis; Chemical and Drug Induced Liver Injury; Drug Therapy, Combination; Fatigue; Histones; Humans; Isotretinoin; Middle Aged; Myelodysplastic Syndromes; Pneumonia; Protein Processing, Post-Translational; Treatment Outcome; Valproic Acid

2007

Other Studies

10 other study(ies) available for valproic acid and isotretinoin

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
On the ability of birth defects monitoring to detect new teratogens.
    American journal of epidemiology, 1987, Volume: 126, Issue:1

    Topics: Abnormalities, Drug-Induced; Epidemiologic Methods; Humans; Infant, Newborn; Isotretinoin; Risk; Teratogens; Thalidomide; Tretinoin; Valproic Acid

1987
Low serum concentration of all-trans and 13-cis retinoic acids in patients treated with phenytoin, carbamazepine and valproate. Possible relation to teratogenicity.
    Archives of toxicology, 1995, Volume: 69, Issue:8

    Topics: Adult; Anticonvulsants; Carbamazepine; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Humans; Isotretinoin; Male; Middle Aged; Phenytoin; Teratogens; Tretinoin; Valproic Acid

1995
A risk assessment of topical tretinoin as a potential human developmental toxin based on animal and comparative human data.
    Journal of the American Academy of Dermatology, 1997, Volume: 36, Issue:3 Pt 2

    Topics: Abnormalities, Drug-Induced; Administration, Topical; Animals; Female; Humans; Isotretinoin; Keratolytic Agents; Methotrexate; Pregnancy; Risk Assessment; Teratogens; Thalidomide; Tretinoin; Valproic Acid

1997
Isotretinoin treatment of a woman with bipolar disorder.
    The Journal of clinical psychiatry, 1999, Volume: 60, Issue:6

    Topics: Acne Vulgaris; Adult; Bipolar Disorder; Comorbidity; Drug Therapy, Combination; Female; Humans; Isotretinoin; Keratolytic Agents; Lithium; Perphenazine; Valproic Acid

1999
Photocarcinogenesis of topical tazarotene and isotretinoin alone and in combination with valproic acid in hairless mice.
    Experimental dermatology, 2008, Volume: 17, Issue:11

    Topics: Administration, Cutaneous; Animals; Carcinogens; Dermatologic Agents; Dose-Response Relationship, Radiation; Female; Isotretinoin; Kaplan-Meier Estimate; Mice; Mice, Hairless; Nicotinic Acids; Photochemical Processes; Skin; Skin Neoplasms; Ultraviolet Rays; Valproic Acid

2008