valproic acid and isomethyleugenol

valproic acid has been researched along with isomethyleugenol in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19903 (16.67)18.7374
1990's3 (16.67)18.2507
2000's3 (16.67)29.6817
2010's7 (38.89)24.3611
2020's2 (11.11)2.80

Authors

AuthorsStudies
Albinsson, A; Gyllenhaal, O1
Carl, GF1
Kawai, S; Kondo, K; Nakamura, M; Nishioka, R; Takeuchi, M1
Alonso, E; Martín-Rodríguez, JC; Pérez-Miguelsanz, J; Puerta, J; Ubeda, N; Varela-Moreiras, G1
Kotani, E; Takeya, T; Tobinaga, S; Watanabe, A; Yoshiike, M1
Achón, M; Alonso-Aperte, E; Pérez-Miguelsanz, J; Ubeda, N; Varela-Moreiras, G1
Deutsch, J; Rapoport, SI; Rosenberger, TA1
Costa, E; Davis, J; Dong, E; Doueiri, MS; Grayson, DR; Guidotti, A; Pinna, G; Rodriguez-Menendez, V; Tremolizzo, L; Tueting, P1
Costa, E; Dong, E; Grayson, DR; Guidotti, A1
Costa, E; Davis, JM; Guidotti, A; Kadriu, B; Pibiri, F; Tueting, P; Veldic, M1
Balmer, NV; Chambers, SM; Hescheler, J; Ivanova, VN; Jagtap, S; Leist, M; Nikolaeva, E; Sachinidis, A; Waldmann, T; Weng, MK; Zimmer, B1
Chen, LH; Cheng, LY; Cherng, CG; Kao, GS; Su, CC; Tzeng, WY; Wang, CY; Yu, L1
Bator, E; Latusz, J; Maćkowiak, M; Mordalska, P; Wędzony, K1
Balmer, NV; Berthold, MR; Hengstler, JG; Henry, M; Ivanova, VN; Klima, S; Kolde, R; Leist, M; Meganathan, K; Rahnenführer, J; Rempel, E; Sachinidis, A; Waldmann, T; Weng, MK1
Ganai, SA; Kalladi, SM; Mahadevan, V1
Hwangbo, MH; Kim, IK; Lee, HA; Park, KM; Seok, YM1
Kanbur, E; Stanley, BA; Tümer, E; Yerlikaya, A1
Bronsema, A; Guerreiro, H; Kresbach, C; Rutkowski, S; Schüller, U; Winkler, B1

Reviews

1 review(s) available for valproic acid and isomethyleugenol

ArticleYear
The Ubiquitin-Proteasome Pathway and Epigenetic Modifications in Cancer.
    Anti-cancer agents in medicinal chemistry, 2021, Volume: 21, Issue:1

    Topics: Acetylation; Boron Compounds; Bortezomib; DNA Modification Methylases; Enzyme Inhibitors; Epigenesis, Genetic; Glycine; Histone Acetyltransferases; Histone Deacetylases; Humans; Hydroxamic Acids; Methylation; Neoplasms; NF-kappa B; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Processing, Post-Translational; Signal Transduction; Terphenyl Compounds; Ubiquitin; Ubiquitination; Valproic Acid

2021

Other Studies

17 other study(ies) available for valproic acid and isomethyleugenol

ArticleYear
Gas chromatographic determination of valproate in minute serum samples after extractive methylation.
    Journal of chromatography, 1978, Nov-21, Volume: 161

    Topics: Chromatography, Gas; Humans; Methylation; Valproic Acid

1978
Effect of chronic valproate treatment on folate-dependent methyl biosynthesis in the rat.
    Neurochemical research, 1986, Volume: 11, Issue:5

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Brain; Carbon; Folic Acid; Glycine Hydroxymethyltransferase; Liver; Male; Methionine Adenosyltransferase; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Oxidoreductases Acting on CH-NH Group Donors; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Valproic Acid

1986
Improved direct injection method and extractive methylation method for determination of valproic acid in serum by gas chromatography.
    Journal of chromatography, 1985, Jul-12, Volume: 342, Issue:1

    Topics: Chromatography, Gas; Epilepsy; Humans; Methylation; Valproic Acid

1985
Valproate-induced developmental modifications maybe partially prevented by coadministration of folinic acid and S-adenosylmethionine.
    The International journal of developmental biology, 1996, Volume: Suppl 1

    Topics: Abnormalities, Drug-Induced; Animals; Anticonvulsants; Bone and Bones; Female; Fetus; Leucovorin; Liver; Methionine; Methylation; Neural Tube Defects; Pregnancy; Rats; Rats, Wistar; S-Adenosylmethionine; Valproic Acid

1996
Oxygenation reaction of methyl valproate with a mono-oxygenase model reagent: implication for stereochemical identification of the mammalian metabolites of valproic acid.
    Chemical & pharmaceutical bulletin, 1997, Volume: 45, Issue:6

    Topics: Animals; Ferrous Compounds; Indicators and Reagents; Liver; Methylation; Models, Chemical; Oxidation-Reduction; Rats; Stereoisomerism; Valproic Acid

1997
Impaired methionine synthesis and hypomethylation in rats exposed to valproate during gestation.
    Neurology, 1999, Mar-10, Volume: 52, Issue:4

    Topics: Analysis of Variance; Animals; Female; Folic Acid; Gestational Age; Homocysteine; Methionine; Methylation; Rats; Rats, Wistar; Valproic Acid

1999
Valproyl-CoA and esterified valproic acid are not found in brains of rats treated with valproic acid, but the brain concentrations of CoA and acetyl-CoA are altered.
    Neurochemical research, 2003, Volume: 28, Issue:6

    Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Animals; Brain; Chromatography, Gas; Coenzyme A; Esters; Fatty Acids; Kinetics; Male; Methylation; Rats; Rats, Inbred F344; Valproic Acid

2003
Valproate corrects the schizophrenia-like epigenetic behavioral modifications induced by methionine in mice.
    Biological psychiatry, 2005, Mar-01, Volume: 57, Issue:5

    Topics: Aggression; Animals; Anticonvulsants; Behavior, Animal; Benzodiazepines; Blotting, Western; Cell Adhesion Molecules, Neuronal; Chromosome Mapping; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Epilepsy; Extracellular Matrix Proteins; Frontal Lobe; GABA Modulators; Histones; Imidazoles; Immunohistochemistry; Interpersonal Relations; Male; Methionine; Methylation; Mice; Motor Activity; Nerve Tissue Proteins; Neural Inhibition; Promoter Regions, Genetic; Reelin Protein; Reflex, Startle; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; S-Adenosylmethionine; Schizophrenia; Serine Endopeptidases; Time Factors; Valproic Acid

2005
Histone hyperacetylation induces demethylation of reelin and 67-kDa glutamic acid decarboxylase promoters.
    Proceedings of the National Academy of Sciences of the United States of America, 2007, Mar-13, Volume: 104, Issue:11

    Topics: Acetylation; Animals; Cell Adhesion Molecules, Neuronal; Cytosine; DNA Methylation; Down-Regulation; Extracellular Matrix Proteins; Glutamate Decarboxylase; Histones; Isoenzymes; Male; Methylation; Mice; Nerve Tissue Proteins; Promoter Regions, Genetic; Reelin Protein; Serine Endopeptidases; Time Factors; Valproic Acid

2007
L-methionine decreases dendritic spine density in mouse frontal cortex.
    Neuroreport, 2010, Jun-02, Volume: 21, Issue:8

    Topics: Animals; Anticonvulsants; Cell Adhesion Molecules, Neuronal; Cell Differentiation; Cell Shape; Dendritic Spines; Disease Models, Animal; Down-Regulation; Drug Interactions; Extracellular Matrix Proteins; Frontal Lobe; GABA Agents; Male; Methionine; Methylation; Mice; Nerve Tissue Proteins; Neuroprotective Agents; Neurotoxins; Reelin Protein; Schizophrenia; Serine Endopeptidases; Synapses; Valproic Acid

2010
Epigenetic changes and disturbed neural development in a human embryonic stem cell-based model relating to the fetal valproate syndrome.
    Human molecular genetics, 2012, Sep-15, Volume: 21, Issue:18

    Topics: Abnormalities, Drug-Induced; Antigens, Differentiation; Basic Helix-Loop-Helix Transcription Factors; Cell Differentiation; Cells, Cultured; Embryonic Stem Cells; Epigenesis, Genetic; Eye Proteins; Histone Deacetylase Inhibitors; Histones; Homeodomain Proteins; Humans; Hydroxamic Acids; Methylation; Nanog Homeobox Protein; Neural Plate; Neural Stem Cells; Neuroepithelial Cells; Octamer Transcription Factor-3; Oligonucleotide Array Sequence Analysis; Paired Box Transcription Factors; PAX6 Transcription Factor; Principal Component Analysis; Promoter Regions, Genetic; Protein Processing, Post-Translational; Repressor Proteins; Transcription, Genetic; Transcriptome; Valproic Acid

2012
Neonatal isolation decreases cued fear conditioning and frontal cortical histone 3 lysine 9 methylation in adult female rats.
    European journal of pharmacology, 2012, Dec-15, Volume: 697, Issue:1-3

    Topics: Acoustic Stimulation; Age Factors; Animals; Animals, Newborn; Azacitidine; Behavior, Animal; Cerebral Cortex; Conditioning, Psychological; Corticosterone; Cues; Decitabine; DNA Modification Methylases; Dose-Response Relationship, Drug; Down-Regulation; Estradiol; Fear; Female; Histone Deacetylase Inhibitors; Histones; Light; Lysine; Maternal Deprivation; Methylation; Photic Stimulation; Rats; Rats, Sprague-Dawley; Reflex, Startle; Stress, Psychological; Valproic Acid

2012
Prenatal MAM administration affects histone H3 methylation in postnatal life in the rat medial prefrontal cortex.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2014, Volume: 24, Issue:2

    Topics: Animals; Astrocytes; Body Weight; Brain; Enzyme Inhibitors; Glutamate Decarboxylase; Histone Demethylases; Histone-Lysine N-Methyltransferase; Histones; Male; Methylation; Methylazoxymethanol Acetate; Methyltransferases; Neurons; Oxidoreductases, N-Demethylating; Prefrontal Cortex; Rats; Rats, Wistar; RNA, Messenger; Sensory Gating; Teratogens; Valproic Acid

2014
From transient transcriptome responses to disturbed neurodevelopment: role of histone acetylation and methylation as epigenetic switch between reversible and irreversible drug effects.
    Archives of toxicology, 2014, Volume: 88, Issue:7

    Topics: Acetylation; Cell Differentiation; Embryonic Stem Cells; Epigenesis, Genetic; Eye Proteins; Gene Expression Regulation; Histone Deacetylase Inhibitors; Histones; Homeodomain Proteins; Humans; Hydroxamic Acids; Methylation; Paired Box Transcription Factors; PAX6 Transcription Factor; Repressor Proteins; Time Factors; Transcriptome; Valproic Acid

2014
HDAC inhibition through valproic acid modulates the methylation profiles in human embryonic kidney cells.
    Journal of biomolecular structure & dynamics, 2015, Volume: 33, Issue:6

    Topics: Catalytic Domain; Epigenesis, Genetic; Gene Expression Regulation; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; HEK293 Cells; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Humans; Ligands; Methylation; Models, Molecular; Molecular Conformation; Protein Binding; Protein Kinase C beta; Valproic Acid

2015
Lysine deacetylase inhibition attenuates hypertension and is accompanied by acetylation of mineralocorticoid receptor instead of histone acetylation in spontaneously hypertensive rats.
    Naunyn-Schmiedeberg's archives of pharmacology, 2016, Volume: 389, Issue:7

    Topics: Acetylation; Age Factors; Animals; Antihypertensive Agents; Blood Pressure; Disease Models, Animal; Gene Expression Profiling; Gene Expression Regulation; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Hypertension; Immediate-Early Proteins; Methylation; Oligonucleotide Array Sequence Analysis; Promoter Regions, Genetic; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Mineralocorticoid; RNA Polymerase II; Transcription Factors; Valproic Acid

2016
Long-term survival of an adolescent glioblastoma patient under treatment with vinblastine and valproic acid illustrates importance of methylation profiling.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2022, Volume: 38, Issue:2

    Topics: Adolescent; Brain Neoplasms; Glioblastoma; Humans; Methylation; Prognosis; Temozolomide; Valproic Acid; Vinblastine

2022