valproic acid has been researched along with inositol 1,4,5-trisphosphate in 9 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 5 (55.56) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dixon, JF; Hokin, LE; Los, GV | 1 |
| Dixon, JF; Hokin, LE | 1 |
| Cheng, L; Harwood, AJ; Mudge, AW; Williams, RS | 1 |
| Adley, K; Chadborn, NH; Eickholt, BJ; Eikel, D; Harwood, AJ; Nau, H; Ryves, WJ; Towers, GJ; Williams, RS; Ylinen, LM | 1 |
| Bialer, M; Dalton, EC; Ewan, K; Eyal, S; Harwood, AJ; Jenkins, A; Pessah, N; Shimshoni, JA; Williams, RS; Yagen, B | 1 |
| Adley, KE; Jin, T; Lee, VW; Maniak, M; Müller-Taubenberger, A; Pawolleck, N; Sihra, TS; Wiedemann, C; Williams, RS; Xu, X | 1 |
| Nurrish, SJ; Saiardi, A; Tokuoka, SM | 1 |
| Chmielowska, M; Gajewska, A; Herman, A; Kalisz, M; Martynska, L; Skrzypska, J; Wasilewska-Dziubinska, E; Wolinska-Witort, E | 1 |
| Cheng, S; Janin, A; Ji, MM; Liu, H; Shen, Y; Wang, L; Xu, PP; Xue, W; Zhan, Q; Zhao, WL; Zhao, X; Zhao, Y | 1 |
9 other study(ies) available for valproic acid and inositol 1,4,5-trisphosphate
| Article | Year |
|---|---|
A novel action of lithium: stimulation of glutamate release and inositol 1,4,5 trisphosphate accumulation via activation of the N-methyl D-aspartate receptor in monkey and mouse cerebral cortex slices.
Topics: Animals; Calcium Channels; Cerebral Cortex; Cyclopentanes; Excitatory Amino Acid Antagonists; Glutamic Acid; Haplorhini; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Lithium; Mice; Piperazines; Receptors, Cytoplasmic and Nuclear; Receptors, N-Methyl-D-Aspartate; Valproic Acid | 1996 |
The antibipolar drug valproate mimics lithium in stimulating glutamate release and inositol 1,4,5-trisphosphate accumulation in brain cortex slices but not accumulation of inositol monophosphates and bisphosphates.
Topics: Animals; Antidepressive Agents; Antimanic Agents; Bipolar Disorder; Cerebral Cortex; Drug Interactions; Glutamic Acid; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Lithium; Male; Mice; Mice, Inbred ICR; Molecular Mimicry; Receptors, N-Methyl-D-Aspartate; Valproic Acid | 1997 |
A common mechanism of action for three mood-stabilizing drugs.
Topics: Animals; Animals, Newborn; Antimanic Agents; Bipolar Disorder; Calcium-Calmodulin-Dependent Protein Kinases; Carbamazepine; Cell Aggregation; Chemotaxis; Dictyostelium; Ganglia, Spinal; Genes, Protozoan; Glycogen Synthase Kinases; Growth Cones; Histone Deacetylase Inhibitors; Histone Deacetylases; Hydroxamic Acids; Inositol 1,4,5-Trisphosphate; Lithium; Mice; Mutation; Neurons, Afferent; Rats; Signal Transduction; Valproic Acid | 2002 |
Effects of valproic acid derivatives on inositol trisphosphate depletion, teratogenicity, glycogen synthase kinase-3beta inhibition, and viral replication: a screening approach for new bipolar disorder drugs derived from the valproic acid core structure.
Topics: Animals; Bipolar Disorder; Cell Line; Drug Evaluation, Preclinical; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; HIV-1; Humans; Inositol 1,4,5-Trisphosphate; Rats; Teratogens; Valproic Acid; Virus Replication | 2005 |
The effects of central nervous system-active valproic acid constitutional isomers, cyclopropyl analogs, and amide derivatives on neuronal growth cone behavior.
Topics: Animals; Anticonvulsants; Cells, Cultured; Dictyostelium; Ganglia, Spinal; Growth Cones; Inositol 1,4,5-Trisphosphate; Rats; Rats, Sprague-Dawley; Signal Transduction; Valproic Acid; Wnt Proteins | 2007 |
Attenuation of phospholipid signaling provides a novel mechanism for the action of valproic acid.
Topics: Animals; Anticonvulsants; Chemotaxis; Dictyostelium; Endocytosis; Enzyme Inhibitors; Exocytosis; Humans; Inositol 1,4,5-Trisphosphate; Phosphatidylinositol 3-Kinases; Phospholipids; Protozoan Proteins; Rats; Recombinant Fusion Proteins; Signal Transduction; Valproic Acid | 2007 |
The mood stabilizer valproate inhibits both inositol- and diacylglycerol-signaling pathways in Caenorhabditis elegans.
Topics: Acetylcholine; Animals; Antimanic Agents; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Carrier Proteins; Defecation; Diglycerides; Inositol; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Inositol Phosphates; Muscle Contraction; Mutation; Ovulation; Phosphatidylinositol 4,5-Diphosphate; Signal Transduction; Valproic Acid | 2008 |
The effect of valproate (VPA) treatment on inositol phosphates (IPs) accumulation in non-stimulated and GnRH-treated female rat anterior pituitary cells in vitro.
Topics: Animals; Cells, Cultured; Chromatography, Ion Exchange; Female; GABA Agents; Gonadotrophs; Gonadotropin-Releasing Hormone; Inositol 1,4,5-Trisphosphate; Luteinizing Hormone; Pituitary Gland, Anterior; Protein Kinase C; Rats; Rats, Wistar; Signal Transduction; Up-Regulation; Valproic Acid | 2013 |
Induction of autophagy by valproic acid enhanced lymphoma cell chemosensitivity through HDAC-independent and IP3-mediated PRKAA activation.
Topics: AMP-Activated Protein Kinases; Antineoplastic Agents; Autophagy; Cell Line, Tumor; Drug Synergism; Enzyme Activation; Humans; Inositol 1,4,5-Trisphosphate; Lymphoma; Mitochondria; Signal Transduction; Sirolimus; Valproic Acid | 2015 |