valproic acid has been researched along with hki 272 in 3 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Avogadri-Connors, F; Booth, L; Cutler, RE; Dent, P; Kirkwood, J; Lalani, AS; Poklepovic, A; Roberts, JL; Sander, C | 1 |
| Booth, L; Cutler, RE; Dent, P; Diala, I; Lalani, AS; Poklepovic, A; Rais, R; Roberts, JL | 1 |
| Booth, L; Dent, P; Hancock, JF; Hoff, DV; Poklepovic, A | 1 |
3 other study(ies) available for valproic acid and hki 272
| Article | Year |
|---|---|
The levels of mutant K-RAS and mutant N-RAS are rapidly reduced in a Beclin1 / ATG5 -dependent fashion by the irreversible ERBB1/2/4 inhibitor neratinib.
Topics: Antineoplastic Combined Chemotherapy Protocols; Autophagy-Related Protein 5; Beclin-1; Cell Line, Tumor; Dose-Response Relationship, Drug; Down-Regulation; Drug Evaluation, Preclinical; Drug Synergism; ErbB Receptors; GTP Phosphohydrolases; Histone Deacetylase Inhibitors; Humans; Membrane Proteins; Neoplasms; Phenylbutyrates; Proto-Oncogene Proteins p21(ras); Quinolines; Receptor, ErbB-2; Receptor, ErbB-4; Valproic Acid | 2018 |
Palbociclib augments Neratinib killing of tumor cells that is further enhanced by HDAC inhibition.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Drug Synergism; Female; Histone Deacetylase Inhibitors; Humans; Mice; Ovarian Neoplasms; Piperazines; Pyridines; Quinolines; Valproic Acid; Xenograft Model Antitumor Assays | 2019 |
Enhanced signaling via ERBB3/PI3K plays a compensatory survival role in pancreatic tumor cells exposed to [neratinib + valproate].
Topics: Cell Line, Tumor; Cell Survival; Humans; MAP Kinase Signaling System; Models, Biological; Pancreatic Neoplasms; Phosphatidylinositol 3-Kinases; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyrimidines; Quinazolines; Quinolines; Receptor, ErbB-3; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; TOR Serine-Threonine Kinases; Valproic Acid | 2020 |