Compounds > valproic acid

valproic acid and gossypol

valproic acid has been researched along with gossypol in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Cai, JY; He, XH; Ji, YH; Ouyang, DY; Saltis, M; Xu, LH; Zha, QB; Zhang, YT1
Cai, JY; He, XH; Huang, MY; Lin, QR; Ouyang, DY; Pan, H; Xu, LH; Zhao, GX1
Chen, XH; Gong, Y; Ni, ZH; Zhang, X; Zou, ZM1

Other Studies

4 other study(ies) available for valproic acid and gossypol

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Valproic acid synergistically enhances the cytotoxicity of gossypol in DU145 prostate cancer cells: an iTRTAQ-based quantitative proteomic analysis.
    Journal of proteomics, 2011, Sep-06, Volume: 74, Issue:10

    Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; DNA Damage; Drug Synergism; Energy Metabolism; Gossypol; Histone Deacetylase Inhibitors; Humans; Male; Mitochondria; Prostatic Neoplasms; Proteomics; Valproic Acid

2011
The BH3-mimetic gossypol and noncytotoxic doses of valproic acid induce apoptosis by suppressing cyclin-A2/Akt/FOXO3a signaling.
    Oncotarget, 2015, Nov-17, Volume: 6, Issue:36

    Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cyclin A2; Female; Forkhead Box Protein O3; Forkhead Transcription Factors; Gossypol; HeLa Cells; Heterografts; Humans; Mice; Mice, Inbred BALB C; Peptide Fragments; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Signal Transduction; Valproic Acid

2015
Valproic Acid Enhances the Anti-tumor Effect of (-)-gossypol to Burkitt Lymphoma Namalwa Cells.
    Biomedical and environmental sciences : BES, 2015, Volume: 28, Issue:10

    Topics: Antineoplastic Agents; Apoptosis; Burkitt Lymphoma; Cell Line, Tumor; Contraceptive Agents, Male; Drug Synergism; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Gossypol; Humans; Valproic Acid

2015