valproic acid and ganciclovir

valproic acid has been researched along with ganciclovir in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (31.58)29.6817
2010's11 (57.89)24.3611
2020's2 (10.53)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Klass, CM; Krug, LT; Offermann, MK; Pozharskaya, VP1
Corbett, G; Gandhi, MK; Jones, K; Nourse, J1
Joshi, G; Kothari, V; Mulherkar, R; Nama, S; Somasundaram, K1
Airenne, K; Alasaarela, L; Määttä, AM; Pikkarainen, J; Samaranayake, H; Stedt, H; Ylä-Herttuala, S1
Adachi, A; Chihara, K; Hino, Y; Ibusuki, C; Kimura, K; Nakamura, S; Suematsu, N; Takahashi, N; Takata, M1
Chang, KP; Chang, YS; Fan, HC; Hsieh, CH; Hsu, CL; Huang, Y; Huang, YC; Kuo, YC; Lee, LY; Li, HP; Lin, AC; Lin, TL; Lui, KW; Wang, HM1
de Greeuw, I; Eersels, JLH; Greijer, AE; Middeldorp, JM; Molthoff, CFM; Novalić, Z; Verkuijlen, SAWM; Verlaan, M1
Jain, V; Kamble, V; Nanda, A; Patel, H; Warawdekar, UM1

Reviews

1 review(s) available for valproic acid and ganciclovir

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

18 other study(ies) available for valproic acid and ganciclovir

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
The targeting of primary effusion lymphoma cells for apoptosis by inducing lytic replication of human herpesvirus 8 while blocking virus production.
    Blood, 2005, May-15, Volume: 105, Issue:10

    Topics: Antiviral Agents; Apoptosis; Cell Line; DNA-Directed DNA Polymerase; Foscarnet; Ganciclovir; Herpesvirus 8, Human; Humans; Lymphoma; Nucleic Acid Synthesis Inhibitors; RNA, Messenger; Valproic Acid; Viral Proteins; Virus Assembly; Virus Replication

2005
Sodium valproate in combination with ganciclovir induces lysis of EBV-infected lymphoma cells without impairing EBV-specific T-cell immunity.
    International journal of laboratory hematology, 2010, Volume: 32, Issue:1 Pt 1

    Topics: Antiviral Agents; Epstein-Barr Virus Infections; Fatal Outcome; Ganciclovir; Histone Deacetylase Inhibitors; Humans; Lymphoma, Large B-Cell, Diffuse; Male; Middle Aged; Neoplasm Recurrence, Local; T-Lymphocytes; Valproic Acid

2010
HDAC inhibitor valproic acid enhances tumor cell kill in adenovirus-HSVtk mediated suicide gene therapy in HNSCC xenograft mouse model.
    International journal of cancer, 2010, Feb-01, Volume: 126, Issue:3

    Topics: Adenoviruses, Human; Animals; Bystander Effect; Carcinoma, Squamous Cell; Cell Line, Tumor; Combined Modality Therapy; Defective Viruses; Female; Ganciclovir; Genes, Transgenic, Suicide; Genetic Therapy; Genetic Vectors; Head and Neck Neoplasms; Histone Deacetylase Inhibitors; Humans; Mice; Mice, Nude; Prodrugs; Simplexvirus; Thymidine Kinase; Valproic Acid; Xenograft Model Antitumor Assays

2010
Improved therapeutic effect on malignant glioma with adenoviral suicide gene therapy combined with temozolomide.
    Gene therapy, 2013, Volume: 20, Issue:12

    Topics: Adenoviruses, Human; Animals; Antineoplastic Agents, Alkylating; Antiviral Agents; Combined Modality Therapy; Dacarbazine; Ganciclovir; Genes, Transgenic, Suicide; Genes, Viral; Genetic Therapy; Genetic Vectors; Glioma; Herpesvirus 1, Human; Humans; Male; Neoplasms, Experimental; Rats; Temozolomide; Thymidine Kinase; Treatment Outcome; Tumor Cells, Cultured; Valproic Acid

2013
[Case report; drug-induced hypersensitivity syndrome following meningoencephalitis associated with human herpes virus-6].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2013, Oct-10, Volume: 102, Issue:10

    Topics: Aged; Antiviral Agents; Biomarkers; Cytokines; Diagnosis, Differential; DNA, Viral; Drug Hypersensitivity Syndrome; Ganciclovir; Herpesvirus 6, Human; Humans; Lymphocyte Activation; Male; Meningoencephalitis; Methylprednisolone; Phenobarbital; Prednisolone; Pulse Therapy, Drug; T-Lymphocytes; Valproic Acid; Virus Activation

2013
Application of a patient-derived xenograft model in cytolytic viral activation therapy for nasopharyngeal carcinoma.
    Oncotarget, 2015, Oct-13, Volume: 6, Issue:31

    Topics: Animals; Anticonvulsants; Antimetabolites, Antineoplastic; Antiviral Agents; Apoptosis; Carcinoma; Cell Proliferation; Deoxycytidine; DNA, Viral; Drug Therapy, Combination; Epstein-Barr Virus Infections; Ganciclovir; Gemcitabine; Gene Expression Profiling; Herpesvirus 4, Human; Humans; Immunoenzyme Techniques; Male; Mice; Mice, Inbred NOD; Mice, SCID; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplasm Recurrence, Local; Oncolytic Virotherapy; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Valproic Acid; Viral Load; Virus Activation; Xenograft Model Antitumor Assays

2015
Cytolytic virus activation therapy and treatment monitoring for Epstein-Barr virus associated nasopharyngeal carcinoma in a mouse tumor model.
    Journal of medical virology, 2017, Volume: 89, Issue:12

    Topics: Animals; Antiviral Agents; Carcinoma; Deoxycytidine; Disease Models, Animal; DNA, Viral; Epstein-Barr Virus Infections; Ganciclovir; Gemcitabine; Herpesvirus 4, Human; Humans; Mice; Mice, Nude; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Treatment Outcome; Tumor Cells, Cultured; Valproic Acid; Viral Load; Virus Activation

2017
Modifying gap junction communication in cancer therapy.
    Current research in translational medicine, 2021, Volume: 69, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Cadherins; Cell Communication; Cell Line, Tumor; Cell Membrane; Connexins; Dexamethasone; Ganciclovir; Gap Junctions; Gene Expression Regulation, Neoplastic; HeLa Cells; Histone Deacetylase Inhibitors; Humans; Molecular Targeted Therapy; Neoplasms; Tretinoin; Valproic Acid

2021