valproic acid and fenfluramine

valproic acid has been researched along with fenfluramine in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19903 (20.00)18.7374
1990's0 (0.00)18.2507
2000's3 (20.00)29.6817
2010's3 (20.00)24.3611
2020's6 (40.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Glen, RC; Lowe, R; Mitchell, JB1
Hudson, JI; Pope, HG1
Aicardi, J; Gastaut, H; Misès, J1
Lerer, B1
Ceulemans, B; Copmans, D; Crawford, AD; de Witte, PA; Esguerra, CV; Kecskés, A; Lagae, L; Langlois, M; Zhang, Y1
Boyd, B; Farfel, GM; Galer, BS; Gammaitoni, A; Smith, S1
Ferretti, A; Pietrafusa, N; Specchio, N; Trivisano, M; Vigevano, F1
Conway, E; Devinsky, O; King, L; Price, D; Schwartz, D1
Ceulemans, B; Maes, P; Schoonjans, A1
Bonaventura, CD; Capovilla, G; Coppola, A; Elia, M; Ferlazzo, E; Gobbi, G; Marini, C; Meletti, S; Riva, A; Romeo, A; Santoro, K; Striano, P; Verrotti, A1
Battino, D; Bromley, R; Kochen, S; Meador, KJ; Pennell, PB; Thomas, SV; Tomson, T1
Schubert-Bast, S; Strzelczyk, A1

Reviews

4 review(s) available for valproic acid and fenfluramine

ArticleYear
Antidepressant drug therapy for bulimia: current status.
    The Journal of clinical psychiatry, 1986, Volume: 47, Issue:7

    Topics: Antidepressive Agents; Bupropion; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Feeding and Eating Disorders; Fenfluramine; Humans; Hyperphagia; Lithium; Lithium Carbonate; Methamphetamine; Monoamine Oxidase Inhibitors; Nomifensine; Phenytoin; Placebos; Propiophenones; Valproic Acid

1986
Alternative therapies for bipolar disorder.
    The Journal of clinical psychiatry, 1985, Volume: 46, Issue:8

    Topics: Ascorbic Acid; Bipolar Disorder; Bupropion; Carbamazepine; Choline; Clonazepam; Clonidine; Clorgyline; Demeclocycline; Fenfluramine; Humans; Methylene Blue; Phosphatidylcholines; Physostigmine; Propiophenones; Propranolol; Spironolactone; Thyroxine; Tryptophan; Valproic Acid

1985
Breastfeeding while on treatment with antiseizure medications: a systematic review from the ILAE Women Task Force
    Epileptic disorders : international epilepsy journal with videotape, 2022, 12-01, Volume: 24, Issue:6

    Topics: Breast Feeding; Cannabidiol; Carbamazepine; Child; Clobazam; Clonazepam; Epilepsy; Ethosuximide; Everolimus; Felbamate; Female; Fenfluramine; Gabapentin; Humans; Infant; Lacosamide; Lamotrigine; Levetiracetam; Oxcarbazepine; Phenobarbital; Phenytoin; Prospective Studies; Tiagabine; Topiramate; Valproic Acid; Vigabatrin; Zonisamide

2022
Psychobehavioural and Cognitive Adverse Events of Anti-Seizure Medications for the Treatment of Developmental and Epileptic Encephalopathies.
    CNS drugs, 2022, Volume: 36, Issue:10

    Topics: Autism Spectrum Disorder; Bromides; Cannabidiol; Clobazam; Cognition; Ethosuximide; Everolimus; Felbamate; Fenfluramine; Humans; Lacosamide; Lamotrigine; Levetiracetam; Pregabalin; Spasms, Infantile; Sulfides; Topiramate; Valproic Acid; Vigabatrin; Zinc Compounds; Zonisamide

2022

Trials

2 trial(s) available for valproic acid and fenfluramine

ArticleYear
Antidepressant drug therapy for bulimia: current status.
    The Journal of clinical psychiatry, 1986, Volume: 47, Issue:7

    Topics: Antidepressive Agents; Bupropion; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Feeding and Eating Disorders; Fenfluramine; Humans; Hyperphagia; Lithium; Lithium Carbonate; Methamphetamine; Monoamine Oxidase Inhibitors; Nomifensine; Phenytoin; Placebos; Propiophenones; Valproic Acid

1986
A phase I, randomized, open-label, single-dose, 3-period crossover study to evaluate the drug-drug interaction between ZX008 (fenfluramine HCl oral solution) and a regimen of stiripentol, clobazam, and valproate in healthy subjects
.
    International journal of clinical pharmacology and therapeutics, 2019, Volume: 57, Issue:1

    Topics: Administration, Oral; Adult; Clobazam; Cross-Over Studies; Dioxolanes; Drug Interactions; Female; Fenfluramine; Healthy Volunteers; Humans; Male; Middle Aged; Non-Smokers; Valproic Acid; Young Adult

2019

Other Studies

10 other study(ies) available for valproic acid and fenfluramine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Syncopal attacks compulsively self-induced by Valsalva's maneuver associated with typical absence seizures. A case report.
    Archives of neurology, 1988, Volume: 45, Issue:8

    Topics: Apnea; Child; Child Behavior; Compulsive Behavior; Electroencephalography; Epilepsy, Absence; Female; Fenfluramine; Humans; Syncope; Valproic Acid; Valsalva Maneuver

1988
Pharmacological characterization of an antisense knockdown zebrafish model of Dravet syndrome: inhibition of epileptic seizures by the serotonin agonist fenfluramine.
    PloS one, 2015, Volume: 10, Issue:5

    Topics: Animals; Anticonvulsants; Disease Models, Animal; Epilepsies, Myoclonic; Fenfluramine; Gene Knockdown Techniques; Humans; Morpholinos; NAV1.1 Voltage-Gated Sodium Channel; Oligonucleotides, Antisense; Selective Serotonin Reuptake Inhibitors; Valproic Acid; Zebrafish; Zebrafish Proteins

2015
Successful use of fenfluramine in nonconvulsive status epilepticus of Dravet syndrome.
    Epilepsia, 2020, Volume: 61, Issue:4

    Topics: Anticonvulsants; Child; Clobazam; Drug Therapy, Combination; Epilepsies, Myoclonic; Fenfluramine; Humans; Male; NAV1.1 Voltage-Gated Sodium Channel; Point Mutation; Selective Serotonin Reuptake Inhibitors; Status Epilepticus; Valproic Acid

2020
Effect of fenfluramine on convulsive seizures in CDKL5 deficiency disorder.
    Epilepsia, 2021, Volume: 62, Issue:7

    Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Epilepsies, Myoclonic; Epilepsy, Tonic-Clonic; Epileptic Syndromes; Female; Fenfluramine; Humans; Lethargy; Male; Seizures; Spasms, Infantile; Treatment Outcome; Valproic Acid; Young Adult

2021
Aggravation of valproic acid induced thrombocytopenia after the introduction of fenfluramine, a case report.
    Seizure, 2021, Volume: 93

    Topics: Anemia; Anticonvulsants; Fenfluramine; Humans; Thrombocytopenia; Valproic Acid

2021
An Italian consensus on the management of Lennox-Gastaut syndrome.
    Seizure, 2022, Volume: 101

    Topics: Anticonvulsants; Cannabidiol; Clobazam; Consensus; Fenfluramine; Humans; Lamotrigine; Lennox Gastaut Syndrome; Quality of Life; Topiramate; Valproic Acid

2022