valproic acid has been researched along with ethosuximide in 305 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 122 (40.00) | 18.7374 |
| 1990's | 58 (19.02) | 18.2507 |
| 2000's | 51 (16.72) | 29.6817 |
| 2010's | 62 (20.33) | 24.3611 |
| 2020's | 12 (3.93) | 2.80 |
| Authors | Studies |
|---|---|
| Johnson, DN; Kilpatrick, BF; Kinnier, WB; Lo, YS; Moses, LM; Sutherland, DB; Taylor, CR; Tomczuk, BE | 1 |
| Mori, Y; Nakamura, J; Sasaki, H; Shibasaki, J | 1 |
| Edafiogho, IO; Farrar, VA; Moore, JA; Nicholson, JM; Scott, KR | 1 |
| Goehring, RR; Greenwood, TD; Nwokogu, GC; Pisipati, JS; Rogers, TG; Wolfe, JF | 1 |
| Kadaba, PK | 1 |
| Conley, JD; Kohn, H | 1 |
| Ciechanowicz-Rutkowska, M; Edafiogho, IO; el-Assadi, A; Farrar, VA; Filippini, G; Grochowski, J; Hinko, CN; Moore, JA; Pilati, T; Serda, P | 1 |
| Covey, DF; Ferrendelli, JA; Hill, MW; Hsiang, BC; Latifi, TN; Reddy, PA; Rothman, SM; Woodward, KE | 1 |
| Flaherty, PT; Greenwood, TD; Manheim, AL; Wolfe, JF | 1 |
| Covey, DF; Ferrendelli, JA; Hill, MW; Hsiang, BC; Latifi, TN; McIlheran, SM; Reddy, PA; Rothman, SM; Woodward, KE | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Bruno-Blanch, L; Gálvez, J; García-Domenech, R | 1 |
| Jolivette, LJ; Ward, KW | 1 |
| Alam, M; Arshad, MF; Bhat, MA; Khan, SA; Pandeya, SN; Rana, A; Siddiqui, N; Stables, J | 1 |
| Alkskas, IA; Azam, F; Khokra, SL; Prakash, O | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Brenneman, D; Cuyckens, F; Finley, MF; Herb, M; Huang, Y; Iannucci, R; Klein, B; Leclercq, L; Liu, Y; Lubin, ML; Malatynska, E; Maryanoff, BE; McComsey, DF; Milewski, ME; Parker, MH; Qin, N; Reitz, AB; Smith-Swintosky, VL; White, HS | 1 |
| Alkskas, IA; Azam, F; El-Gnidi, BA | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| He, X; Hu, X; Wu, W; Wu, Z; Xiao, Y; Zhang, T; Zhong, M | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Chlebek, I; Kamiński, K; Obniska, J; Rzepka, S; Wiklik, B | 1 |
| Brenneman, DE; Finley, MF; Herb, M; Klein, BD; Liu, Y; Lubin, ML; Malatynska, E; Maryanoff, BE; McComsey, DF; Milewski, ME; Parker, MH; Qin, N; Reitz, AB; Smith-Swintosky, VL; White, HS; Wilcox, KS | 1 |
| Baker, MT; Mishra, RK | 1 |
| Kumari, S; Mishra, CB; Tiwari, M | 1 |
| Filipek, B; Kamiński, K; Kieć-Kononowicz, K; Latacz, G; Obniska, J; Rapacz, A; Łuszczki, JJ | 1 |
| Andres-Mach, M; Kamiński, K; Kieć-Kononowicz, K; Latacz, G; Rapacz, A; Zagaja, M; Łuszczki, JJ | 1 |
| Filipek, B; Kamiński, K; Obniska, J; Pękala, E; Powroźnik, B; Rapacz, A; Rybka, S; Żmudzki, P | 1 |
| Edayadulla, N; Ramesh, P | 1 |
| Abram, M; Andres-Mach, M; Kamiński, K; Obniska, J; Rapacz, A; Zagaja, M; Łuszczki, JJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Góra, M; Kamiński, K; Obniska, J; Rapacz, A; Rybka, S; Sałat, K; Żmudzki, P | 1 |
| Filipek, B; Furgała, A; Obniska, J; Rapacz, A; Rybka, S; Żmudzki, P | 1 |
| Filipek, B; Kamiński, K; Obniska, J; Rapacz, A | 1 |
| Filipek, B; Obniska, J; Rapacz, A; Rybka, S; Żmudzki, P | 1 |
| Concepcion, GP; Haygood, MG; Light, A; Lin, Z; Olivera, BM; Schmidt, EW; Smith, MD | 1 |
| Budziszewska, B; Koczurkiewicz, P; Marona, H; Pańczyk, K; Pękala, E; Piska, K; Pytka, K; Rapacz, A; Starek-Świechowicz, B; Waszkielewicz, AM | 1 |
| Jamal Gilani, S; Kala, C; Prakash Dixit, S; Sarim Imam, S; Zaheen Hassan, M | 1 |
| Akhtar, MJ; Bhatia, R; Grover, G; Nath, R | 1 |
| Bohlen, N; Hertl, M | 1 |
| Lascelles, PT; Patsalos, PN | 5 |
| Dreifuss, FE | 1 |
| Flachs, H; Gram, L; Parnas, J | 2 |
| Eadie, MJ; McKauge, L; Smith, GA; Tyrer, JH | 1 |
| Lewis, JR | 1 |
| Penin, H | 1 |
| Goujet, MA; Simon, P | 1 |
| Jeavons, PM | 1 |
| Klotz, U | 1 |
| Conomy, JP | 1 |
| Göbel, W; Löscher, W | 1 |
| Englander, RN; Hanna, GR; Johnson, RN; Nowack, WJ | 1 |
| Newmark, ME; Penry, JK | 1 |
| Reith, H; Schäfer, H | 1 |
| Runci, FM; Segre, G | 1 |
| Crawford, RD; Davis, HL; Johnson, DD | 1 |
| Deisenhammer, E; Sommer, R | 1 |
| Fierz, L; Karbowski, K; Robert, F | 1 |
| Lai, AA; Levy, RH; Lockard, JS; Patel, IH | 1 |
| Congdon, WC; DuCharme, LL; Levy, RH; Lockard, JS; Patel, IH | 1 |
| Brachet, A; Henry, P; Loiseau, P | 1 |
| Frey, HH; Löscher, W | 2 |
| Gastaut, H; Osuntokun, BO | 1 |
| Dam, M; Hvidberg, EF | 1 |
| Mares, P; Stanková, L | 1 |
| Watanabe, M; Yagi, K | 1 |
| Müller, D; Todt, H | 1 |
| Karroum, N; Matthews-Ferrari, K | 1 |
| Declerck, AC; Wauquier, A | 1 |
| Wyllie, E; Wyllie, R | 1 |
| Papazian, O | 1 |
| Joseph, T; Rajesh, KR; Rao, S | 1 |
| Bartels, H; Hebestreit, H; Mingers, AM; Pannenbecker, J | 1 |
| Frey, HH; Wahle, H | 1 |
| Matisová, E; Pham Thi, Ha; Volmut, J | 1 |
| Inoue, Y; Kuroda, Y; Nakanishi M, S; Neshige, R | 1 |
| Cosgrove, M; Pople, S; Wallace, SJ | 1 |
| Czuczwar, SJ; Kleinrok, Z; Małek, U | 1 |
| Blennow, G; Heijbel, J; Sandstedt, P; Tonnby, B | 1 |
| Baty, C; Jambou, J; Leducq, B; Richard, L | 1 |
| Maitre, M; Vayer, P | 1 |
| Coulter, DA; Huguenard, JR; Prince, DA | 1 |
| Aburada, M; Hosoya, E; Iizuka, S; Ishige, A; Matsuzaki, Y; Sakamoto, K; Sekiguchi, K; Sugaya, E | 1 |
| Reynolds, EH; Trimble, MR | 1 |
| Bender, AS; Hertz, L | 1 |
| Snead, OC | 1 |
| Mares, P; Velísek, L | 1 |
| Clark, R; Picker, M; Poling, A; Vande Polder, D | 1 |
| Macdonald, RL; McLean, MJ | 1 |
| Killam, EK; Paule, MG | 1 |
| Blakely, E; Picker, M; Poling, A; White, W | 1 |
| Wallace, SJ | 2 |
| Lee, EK; Walters, JR; Waszczak, BL | 1 |
| Bousquet, E; Puglisi, G; Santagati, NA | 1 |
| Shinnar, S | 1 |
| Browning, RA; Faingold, CL | 1 |
| Meyer, FP; Walther, H | 1 |
| Charlier, B; Maitre, M; Mandel, P; Vayer, P | 1 |
| György, I; Ilyés, I; Princzinger, A; Sári, B | 1 |
| Krall, RL; Resor, SJ | 1 |
| Bourgeois, BF | 2 |
| Piredda, SG; Swinyard, EA; Woodhead, JH | 1 |
| Fromm, GH | 1 |
| Depaulis, A; Marescaux, C; Micheletti, G; Reis, J; Rumbach, L; Vergnes, M; Warter, JM | 1 |
| Blomquist, HK; Zetterlund, B | 1 |
| Dailey, JW; Jobe, PC | 1 |
| Löscher, W; Nau, H | 1 |
| Picker, M; Poling, A; White, W | 1 |
| Marescaux, C; Micheletti, G; Rumbach, L; Vergnes, M; Warter, JM | 1 |
| Baier, WK; Dieterich, E; Doose, H; Fichsel, H; Tuxhorn, I | 1 |
| Baier, WK; Dieterich, E; Doose, H; Fichsel, H | 1 |
| Grossett, D; Picker, M; Poling, A; Vande Polder, D | 1 |
| Freeman, JM; Vining, EP | 1 |
| König, H | 1 |
| Dreifuss, FE; Drury, I | 1 |
| Abbott, LC; Bennett, GD; Finnell, RH; Taylor, SM | 1 |
| Adelman, WJ; Brennan, JJ; Fohlmeister, JF | 1 |
| Maheshwari, MC | 1 |
| Schmidt, D | 2 |
| Ottonello, D; Perria, B; Rosadini, G; Sannita, WG; Timitilli, C | 1 |
| Neuvonen, PJ; Tokola, RA | 1 |
| Mantegazza, P; Martini, A; Panerai, AE; Sacerdote, P | 1 |
| Bearden, LJ; Snead, OC | 1 |
| Rowan, AJ | 1 |
| Crema, A; Perucca, E | 1 |
| de Beer-Pawlikowski, N; Meijer, JW; Meinardi, H; Rowan, AJ; van der Geest, P | 1 |
| Bleck, TP | 1 |
| Asconapé, J; Penry, JK | 1 |
| Reynolds, EH | 1 |
| Callaghan, N; Keating, J; O'Dwyer, R | 1 |
| Albright, PS; Bruni, J | 1 |
| Di Perri, R; Fazio, A; La Rosa, G; Narbone, MC; Oteri, G; Pisani, F; Trunfio, C | 1 |
| Frey, HH; Löscher, W; Reiche, R; Schultz, D | 1 |
| Santavuori, P | 1 |
| Ramsay, RE | 1 |
| Inoue, Y; Röder-Wanner, UU; Tsai, JJ; Wolf, P | 1 |
| Koryntová, H; Mares, P; Maresová, D; Pohl, M; Seidl, J; Velísek, L | 1 |
| Classen, W; Mondadori, C | 1 |
| Picker, M; Poling, A | 1 |
| Porter, RJ; Theodore, WH | 1 |
| De Paiva, VJ; Subirana, A; Subirana, M | 1 |
| Mares, P; Maresová, D; Schickerová, R | 1 |
| Chattha, AS; Fromm, GH; Glass, JD; Martinez, AJ; Silverman, M | 1 |
| Grgurinovich, N; Miners, JO | 1 |
| Franco-Morselli, R; Morselli, PL | 1 |
| Müller, FO; Steyn, JM | 1 |
| Karlov, VA; Savitskaia, ON | 1 |
| Kumps, A; Mardens, Y | 1 |
| Külpmann, WR | 1 |
| Cramer, JA; Mattson, RH | 1 |
| Ayers, GJ; Burnett, D; Goudie, JH; Reed, K | 1 |
| Chattha, AS; Fromm, GH; Glass, JD; Martinez, AJ | 1 |
| Aminoff, MJ | 1 |
| Bustamante, L; Goldensohn, ES; Lueders, H; Pippenger, C | 1 |
| Scollo-Lavizzari, G | 1 |
| Dreifuss, FE; Kupferberg, HJ; Penry, JK; Sackellares, JC; Sato, S; White, BG | 1 |
| Manfredi, C; Zinterhofer, L | 1 |
| Albani, F; Baruzzi, A; Riva, R | 1 |
| Bauer, LA; Harris, C; Levy, RH; Raisys, VA; Wilensky, AJ | 1 |
| Clifford, DB; Dodson, WE; Ferrendelli, JA; Lothman, EW | 1 |
| Cohan, SL | 1 |
| Boldyrev, AI | 1 |
| Koch, KM; Levy, RH | 1 |
| Callaghan, N; Daly, M; O'Driscoll, D; O'Hare, J; O'Neill, B | 1 |
| Cloyd, J; Garnett, WR; Holmes, GL; Meyer, MC; Schiffer, JR | 1 |
| Amit, R; Maytal, J; Vitale, S | 1 |
| Amano, T; Fujita, Y; Hanaya, R; Matsubayashi, H; Sasa, M; Serikawa, T; Ujihara, H; Uozumi, T | 1 |
| Stringer, JL | 1 |
| Badalian, LO; Iskander, MB; Kharlamov, DA; Medvedev, MI; Mukhin, KIu; Temin, PA; Veselov, NK | 1 |
| Korinthenberg, R; Wehrle, L; Zimmerhackl, LB | 1 |
| Hekster, YA; Keyser, A; Lammers, MW; Meinardi, H; Renier, WO; van Lier, H; Wijsman, DJ | 1 |
| Kubová, H; Mares, P; Pohl, M; Zelízko, M | 1 |
| Ferreiro Martín, D; Ribacoba Montero, R; Salas Puig, J | 1 |
| Pellock, JM | 1 |
| Camfield, CS; Camfield, PR; Dooley, JM; Fraser, AD; Gordon, KE | 1 |
| Baba, H; Ono, K; Sugai, S | 1 |
| Bachmann, KA; Jauregui, L | 1 |
| Becker, A; Brosz, M; Grecksch, G | 1 |
| Avanzini, G; Battino, D; Estienne, M | 1 |
| Hirohashi, M; Kitano, Y; Nomura, M; Takasuna, K; Usui, C | 1 |
| Boreus, L; Eriksson, AS; Hoppu, K; Nergårdh, A | 1 |
| Brudniak, T; Czuczwar, SJ; Gasior, M; Kamiński, R; Kleinrok, Z | 1 |
| Perucca, E; Pisani, F; Spina, E | 1 |
| Balian, JD; Mahmood, I | 1 |
| Diomedi, M; Gigli, GL; Masala, C; Placidi, F; Pomponi, MG; Scalise, A; Silvestri, G | 1 |
| Bernasconi, R; Bittiger, H; De Barry, J; Marescaux, C; Mathivet, P | 1 |
| Boenigk, HE; May, T; Sälke-Kellermann, RA | 1 |
| Bartolomei, F; Bureau, M; Dravet, C; Gastaut, JL; Genton, P; Roger, J; Viallat, D | 1 |
| Hechler, V; Maitre, M; Ratomponirina, C | 1 |
| Herranz, JL; Otero, B; Ribacoba, R; Salas-Puig, J; Solar, DM | 1 |
| Anderson, GD | 1 |
| David, J; Joseph, S; Joseph, T | 1 |
| Deckers, CL; Dirksen, R; Meinardi, H; Roks, G; van Egmond, J; van Rijn, CM | 1 |
| Czuczwar, SJ; Kleinrok, Z; Klonowski, P; Tutka, P | 1 |
| D'Mello, SR; LoTurco, JJ; Rattan, S; Sarkisian, MR | 1 |
| Baggot, PJ; Kalamarides, JA; Shoemaker, JD | 1 |
| Fukuhara, N; Ishida, C | 1 |
| Conilleau, V; Dompmartin, A; Leroy, D; Michel, M; Verneuil, L | 1 |
| Alkadhi, KA; Otoom, SA | 1 |
| Cespuglio, R; Debilly, G; Faradji, H; Rousset, C; Vergnes, M | 1 |
| David, J; Joseph, T; Kumaresan, S | 1 |
| Calvani, M; Guaitolini, C; Paolone, G; Parisi, G; Parisi, P | 1 |
| David, J; Joseph, T; Subramanyam, K | 1 |
| Baraban, SC; Barbaro, NM; Smyth, MD | 1 |
| Corley, SM; Gilbert, TH; Teskey, GC | 1 |
| Ono, T | 1 |
| Hattori, H | 1 |
| Oguni, H | 1 |
| Yasuhara, A | 1 |
| Rekling, JC | 1 |
| Posner, E | 6 |
| Marson, AG; Mohamed, K; Posner, EB | 3 |
| Berroya, AG; Bleasel, AF; Bye, AM; Lah, S; Lawson, J; McIntyre, J; Sabaz, M; Webster, R | 1 |
| Papp, Z; Török, L | 1 |
| Hayashi, M; Nagao, H; Wakamoto, H | 1 |
| Borowicz, KK; Czuczwar, SJ; Luszczki, JJ | 1 |
| Czuczwar, SJ; Dekundy, A; Kaminski, RM; Tochman, AM; Turski, WA | 1 |
| Pedersen, AM; Rasmussen, NH | 1 |
| Avantaggiato, P; Cagnana, A; Cardinali, S; Granocchio, E; Lanzi, G; Papalia, G; Veggiotti, P | 1 |
| Aujard, Y; Livet, MO; Ponsot, G | 1 |
| Czuczwar, SJ; Luszczki, JJ; Patsalos, PN; Ratnaraj, N | 2 |
| Gilbert, TH; Teskey, GC | 1 |
| Calderon, A; Palencia, G; Sotelo, J | 1 |
| Feucht, M; Hall, RE; Kindler, J; Mayer, H; Pahs, G; Plattner, B; Steiner, H; Williams, RP | 1 |
| Eggers, AE | 1 |
| Hirvonen, K; Koivikko, M; Kylliäinen, A; Riita, T; Sirén, A; Tenhunen, M | 1 |
| Bortolato, M; Fà, M; Frau, R; Marrosu, F; Mereu, G; Muroni, A; Orrù, M; Puligheddu, M; Tuveri, A | 1 |
| Edelbroek, PM; Vermeij, TA | 1 |
| Wakamoto, H | 1 |
| Aiba, T; Gomita, Y; Kawasaki, H; Kitamura, Y; Kurosaki, Y; Makita, T; Nishihara, S; Ohtsuka, Y; Sendo, T; Ueshima, S | 1 |
| Collins, JJ; Evason, K; Huang, C; Hughes, S; Kornfeld, K | 1 |
| Aleem, IS; Ashraf, A; Cortez, MA; Kanawaty, A; Liu, CC; Sadeghnia, HR; Shen, L; Snead, OC; Stewart, L; Trepanier, CH; Wu, Y | 1 |
| Andres-Mach, MM; Czuczwar, SJ; Dudra-Jastrzebska, M; Luszczki, JJ; Patsalos, PN; Ratnaraj, N | 1 |
| Lagae, L | 1 |
| Penovich, PE; Willmore, LJ | 1 |
| Mula, M | 1 |
| Adamson, PC; Capparelli, EV; Clark, PO; Cnaan, A; Dlugos, D; Glauser, TA; Hirtz, DG; Masur, D; Shinnar, S | 1 |
| Vining, EP | 1 |
| Arzimanoglou, A; Perucca, E; Ryvlin, P | 1 |
| Chiarelli, F; Coppola, G; D'Egidio, C; Parisi, P; Verrotti, A | 1 |
| Gaily, E; Granström, ML; Kantola-Sorsa, E; Liukkonen, E; Paetau, R; Peltola, M | 1 |
| Potera, C | 1 |
| Agostinelli, S; Chiarelli, F; Coppola, G; Curatolo, P; Franzoni, E; Grosso, S; Iannetti, P; Olivieri, C; Parisi, P; Spalice, A; Verrotti, A; Zamponi, N | 1 |
| Andres-Mach, M; Barcicka-Klosowska, B; Czuczwar, SJ; Florek-Luszczki, M; Haratym-Maj, A; Luszczki, JJ | 1 |
| Chae, JH; Choi, JE; Hwang, H; Hwang, YS; Kim, H; Kim, KJ; Kim, SH; Lim, BC | 1 |
| Buchneva, IA; Ermakov, AIu; Ermolenko, NA; Voronkova, KV | 1 |
| Buchneva, IA; Ermakov, AIu; Ermolenko, NA; Voronkova, KV; Zakharova, EI | 1 |
| Borowicz, KK; Czuczwar, SJ; Piskorska, B; Stępniak, B | 1 |
| Antonucci, F; Bozzi, Y; Braida, D; Caleo, M; Clerici, M; Corradini, I; De Astis, S; Donzelli, A; Frassoni, C; Inverardi, F; Lipp, HP; Loos, M; Martucci, R; Matteoli, M; Pattini, L; Sala, M; Verderio, C; Welzl, H; Wolfer, D | 1 |
| Buchneva, IA; Ermakov, AIu; Ermolenko, NA; Kalikina, TA; Zakharova, EI | 1 |
| Adamson, PC; Clark, PO; Cnaan, A; Dlugos, D; Glauser, TA; Hirtz, DG; Masur, D; Shinnar, S | 1 |
| Bialer, M | 1 |
| Desai, J; Mitchell, WG | 1 |
| Jin, DI; Kang, JW; Lee, JE; Lee, SH; Lin, T | 1 |
| Beker van Woudenberg, A; Bouma, M; de Groot, D; Hermsen, S; Menke, A; Piersma, A; Rijkmans, E; Snel, C; Wolterbeek, A | 1 |
| Filipek, B; Kamiński, K; Obniska, J; Rapacz, A; Rybka, S | 1 |
| Borowicz, KK; Popławska, M; Wróblewska, D | 1 |
| Bastin, ML; Cook, AM; Oyler, DR; Smetana, KS | 1 |
| Brigo, F; Igwe, SC | 1 |
| Alarcón-Martínez, H; Casas-Fernández, C; Domingo-Jiménez, R; Ibáñez-Micó, S; Martínez-Ferrández, C; Martínez-Salcedo, E | 1 |
| Godoy, F; Lyons, C; Vanden Driessche, K | 1 |
| Bloch, J; Miranda, MJ | 1 |
| Chalhub, EG; Chen, W | 1 |
| Clark, P; Cnaan, A; Dlugos, D; Glauser, TA; Hirtz, DG; Hu, F; Liu, C; Masur, D; Shinnar, RC; Shinnar, S; Weiss, EF | 1 |
| Crescioli, G; De Masi, S; Guerrini, R; Ilvento, L; Lucenteforte, E; McGreevy, KS; Mugelli, A; Pugi, A; Rosati, A; Virgili, G | 1 |
| Garraghty, PE; Orczyk, JJ | 1 |
| Biraben, A; Costet, N; Dieuset, G; Hadjadj, S; Kuchenbuch, M; Martin, B; Pawluski, JL; Vercueil, L | 1 |
| Abe, K; Hashimura, M; Iha, HA; Iwai, C; Kato, M; Kawaji, S; Kawakita, K; Kunisawa, N; Ogawa, M; Ohno, Y; Shimizu, S | 1 |
| de Baat, C; Vissink, A; Zweers, PGMA | 1 |
| Kessler, SK; McGinnis, E | 1 |
| Brigo, F; Igwe, SC; Lattanzi, S | 2 |
| Berg, AT; Blumenfeld, H; Chung, MH; Dohle, C; Giblin, K; Morse, E | 1 |
| Canafoglia, L; Casellato, S; Dettori, MS; Duran, D; Franceschetti, S; Freri, E; Granata, T; Panzica, F; Ragona, F | 1 |
| Belcastro, V; Brigo, F; Striano, P | 1 |
| Abram, M; Andres-Mach, M; Esguerra, CV; Gawel, K; Jakubiec, M; Kamiński, K; Latacz, G; Lubelska, A; Nieoczym, D; Pieróg, M; Rapacz, A; Socała, K; Szewczyk, A; Szulczyk, B; Wlaź, P; Zagaja, M; Łuszczki, JJ | 1 |
| Cesaroni, E; Cossu, S; Cusmai, R; Di Capua, M; Maiorani, D; Pepi, C; Pruna, D; Specchio, N; Striano, P; Vigevano, F | 1 |
| Czuczwar, SJ; Krzyżanowski, M; Świąder, K; Świąder, MJ; Wróbel, A; Zakrocka, I; Łuszczki, JJ | 1 |
| Bahlo, M; Bello-Espinosa, LE; Bennett, MF; Berkovic, SF; Buchhalter, J; Chan, EK; D'Alfonso, S; Dabscheck, G; Damiano, JA; Grinton, BE; Hildebrand, MS; Myers, KA; Sadleir, LG; Scheffer, IE; Schneider, AL | 1 |
| Coppola, G; Di Bonaventura, C; Donadio, S; Operto, FF; Padovano, C; Pastorino, GMG; Scuoppo, C; Vivenzio, V | 1 |
| Samanta, D | 1 |
| Bobylova, MY; Glukhova, LY; Kuzmich, GV; Mukhin, KY; Pylayeva, OA | 1 |
| Battino, D; Bromley, R; Kochen, S; Meador, KJ; Pennell, PB; Thomas, SV; Tomson, T | 1 |
| Schubert-Bast, S; Strzelczyk, A | 1 |
| Adamson, PC; Blumer, JL; Capparelli, EV; Clark, PO; Cnaan, A; Dong, M; Fukuda, T; Glauser, TA; Mizuno, K; Reed, MD; Shinnar, S; Vinks, AA | 1 |
| Chu, H; Shi, J; Yang, X; Zhang, X; Zhou, Z | 1 |
61 review(s) available for valproic acid and ethosuximide
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Synthetic and therapeutic perspectives of nitrogen containing heterocycles as anti-convulsants.
Topics: Animals; Anticonvulsants; Heterocyclic Compounds; Humans; Molecular Structure; Seizures; Structure-Activity Relationship | 2020 |
Psychotropic effect of antiepileptic drugs.
Topics: Anticonvulsants; Carbamazepine; Ethosuximide; Humans; Mental Processes; Personality Inventory; Phenobarbital; Phenytoin; Psychiatric Status Rating Scales; Psychotropic Drugs; Thiazines; Valproic Acid | 1979 |
[Long-term anticonvulsant therapy (author's transl)].
Topics: Anticonvulsants; Carbamazepine; Chronic Disease; Clonazepam; Epilepsy; Ethosuximide; Humans; Long-Term Care; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1978 |
[Antiepileptics during pregnancy and lactation. Pharmacokinetic data].
Topics: Anticonvulsants; Bromides; Carbamazepine; Clonazepam; Diazepam; Ethosuximide; Female; Fetus; Humans; Kinetics; Lactation; Maternal-Fetal Exchange; Nitrazepam; Phenobarbital; Phenytoin; Pregnancy; Primidone; Valproic Acid | 1979 |
Pharmacological and biochemical studies in epileptic fowl.
Topics: Animals; Anticonvulsants; Benzodiazepinones; Brain; Chickens; Disease Models, Animal; Ethosuximide; Female; Humans; Male; Mutation; Phenobarbital; Phenytoin; Photic Stimulation; Primidone; Seizures; Valproic Acid | 1979 |
Clinical pharmacokinetics of anticonvulsants.
Topics: Administration, Oral; Adult; Aged; Aging; Animals; Anticonvulsants; Carbamazepine; Child; Clonazepam; Diazepam; Drug Interactions; Ethosuximide; Female; Humans; Hydantoins; Infant, Newborn; Injections, Intramuscular; Injections, Intravenous; Intestinal Absorption; Kidney Diseases; Kinetics; Liver Diseases; Milk; Molecular Biology; Phenobarbital; Phenytoin; Pregnancy; Primidone; Valproic Acid | 1976 |
[Neurotoxicity of antiepileptic drugs].
Topics: Adult; Anticonvulsants; Benzodiazepines; Carbamazepine; Child; Ethosuximide; Humans; Male; Nervous System; Nervous System Diseases; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1992 |
Routine laboratory monitoring for serious adverse effects of antiepileptic medications: the controversy.
Topics: Anemia, Aplastic; Anticonvulsants; Carbamazepine; Chemical and Drug Induced Liver Injury; Drug Monitoring; Epilepsy; Ethosuximide; Humans; Leukopenia; Phenytoin; Thrombocytopenia; Valproic Acid | 1991 |
Adverse neuropsychiatric effects of anticonvulsant drugs.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Barbiturates; Benzodiazepines; Biogenic Amines; Carbamazepine; Cerebellar Ataxia; Dystonia; Ethosuximide; Folic Acid Deficiency; Hormones; Humans; Mental Disorders; Nervous System Diseases; Peripheral Nervous System Diseases; Phenytoin; Rats; Tremor; Valproic Acid | 1985 |
The neuropharmacology of epileptic falling spells.
Topics: Anti-Anxiety Agents; Benzodiazepines; Brain; Electroencephalography; Epilepsy; Ethosuximide; Humans; Imipramine; Posture; Valproic Acid | 1987 |
Use of ethosuximide and valproate in the treatment of epilepsy.
Topics: Abnormalities, Drug-Induced; Brain Diseases; Drug Interactions; Epilepsies, Myoclonic; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Ethosuximide; Humans; Status Epilepticus; Succinimides; Trimethadione; Valproic Acid | 1986 |
Antiepileptic drugs in adolescents.
Topics: Adaptation, Psychological; Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Clonazepam; Drug Interactions; Epilepsy; Ethosuximide; Female; Humans; Phenobarbital; Phenytoin; Pregnancy; Primidone; Sports; Valproic Acid | 1987 |
Mechanisms of anticonvulsant drug action. II. Drugs primarily used for absence epilepsy.
Topics: Anticonvulsants; Benzodiazepines; Epilepsy; Ethosuximide; Humans; Kinetics; Valproic Acid | 1987 |
[Thyroid function in children under prolonged anticonvulsant therapy].
Topics: Anticonvulsants; Carbamazepine; Child; Epilepsy; Ethosuximide; Humans; Secretory Rate; Thyroid Gland; Thyroid Hormones; Valproic Acid | 1988 |
Drug treatment of epilepsy.
Topics: Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Valproic Acid | 1987 |
Effects of different classes of antiepileptic drugs on brain-stem pathways.
Topics: Animals; Anticonvulsants; Baclofen; Brain Stem; Carbamazepine; Disease Models, Animal; Electroshock; Ethosuximide; Phenytoin; Reticular Formation; Valproic Acid | 1985 |
Pharmacokinetics of anti-epileptic drugs in the dog: a review.
Topics: Animals; Anticonvulsants; Blood Proteins; Carbamazepine; Clonazepam; Diazepam; Dog Diseases; Dogs; Epilepsy; Ethosuximide; Kinetics; Phenobarbital; Phenytoin; Primidone; Species Specificity; Trimethadione; Valproic Acid | 1985 |
Psychopharmacological aspects of antiepileptic treatment.
Topics: Anticonvulsants; Carbamazepine; Drug Therapy, Combination; Electroencephalography; Epilepsy; Ethosuximide; Humans; Phenytoin; Psychological Tests; Psychometrics; Psychotropic Drugs; Research Design; Sampling Studies; Thiazines; Valproic Acid | 1980 |
Diagnosis and treatment of epilepsy.
Topics: Automatism; Benzodiazepines; Carbamazepine; Electroencephalography; Epilepsies, Partial; Epilepsy; Epilepsy, Temporal Lobe; Ethosuximide; Humans; Muscle Tonus; Phenobarbital; Phenytoin; Primidone; Telemetry; Valproic Acid | 1983 |
Therapy for status epilepticus.
Topics: Acetazolamide; Anesthesia; Anticonvulsants; Barbiturates; Chlormethiazole; Clonazepam; Diazepam; Ethosuximide; Humans; Lidocaine; Lorazepam; Paraldehyde; Phenobarbital; Phenytoin; Status Epilepticus; Valproic Acid | 1983 |
Mental effects of antiepileptic medication: a review.
Topics: Adolescent; Adult; Anticonvulsants; Attention; Barbiturates; Brain Chemistry; Carbamazepine; Child; Drug Therapy, Combination; Epilepsy; Ethosuximide; Folic Acid Deficiency; Humans; Mental Disorders; Mental Processes; Phenytoin; Psychomotor Performance; Psychoses, Substance-Induced; Serotonin; Valproic Acid | 1983 |
The clinical pharmacology of antiepileptic drugs.
Topics: Adult; Anticonvulsants; Benzodiazepines; Carbamazepine; Drug Interactions; Ethosuximide; Female; Half-Life; Humans; Intestinal Absorption; Kidney; Kidney Diseases; Kinetics; Liver Diseases; Phenobarbital; Phenytoin; Pregnancy; Primidone; Protein Binding; Tissue Distribution; Trimethadione; Valproic Acid | 1984 |
Clinical pharmacokinetics of antiepileptic drugs in adults.
Topics: Adult; Aging; Anticonvulsants; Carbamazepine; Clonazepam; Diazepam; Disease; Ethosuximide; Female; Humans; Kinetics; Phenobarbital; Phenytoin; Pregnancy; Primidone; Saliva; Valproic Acid | 1980 |
Pharmacological principles in the long-term treatment of epilepsy.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Diazepam; Epilepsy; Ethosuximide; Humans; Kinetics; Long-Term Care; Phenobarbital; Phenytoin; Primidone; Succinimides; Valproic Acid | 1981 |
Antiepileptic therapeutic drug monitoring.
Topics: Anticonvulsants; Carbamazepine; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1981 |
Drug interactions with valproic acid.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Dose-Response Relationship, Drug; Drug Interactions; Ethosuximide; Fatty Acids, Nonesterified; Humans; Kinetics; Phenobarbital; Phenytoin; Primidone; Salicylates; Valproic Acid | 1982 |
Standard approach to antiepileptic drug treatment in the United States.
Topics: Adult; Anticonvulsants; Benzodiazepines; Carbamazepine; Child; Drug Administration Schedule; Drug Therapy, Combination; Drug Utilization; Epilepsy; Ethosuximide; Humans; Medicine; Phenobarbital; Specialization; United States; Valproic Acid | 1994 |
Clinical pharmacokinetics of antiepileptic drugs in paediatric patients. Part I: Phenobarbital, primidone, valproic acid, ethosuximide and mesuximide.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Epilepsy; Ethosuximide; Humans; Infant; Infant, Newborn; Phenobarbital; Primidone; Succinimides; Valproic Acid | 1995 |
Clinically significant pharmacokinetic drug interactions with carbamazepine. An update.
Topics: Analgesics, Non-Narcotic; Anti-Bacterial Agents; Anticonvulsants; Antidepressive Agents; Carbamazepine; Drug Interactions; Ethosuximide; Felbamate; Humans; Phenobarbital; Phenylcarbamates; Phenytoin; Primidone; Propylene Glycols; Valproic Acid | 1996 |
Myoclonus and epilepsy in childhood: a review of treatment with valproate, ethosuximide, lamotrigine and zonisamide.
Topics: Anticonvulsants; Child; Child, Preschool; Epilepsies, Myoclonic; Ethosuximide; Humans; Infant; Isoxazoles; Lamotrigine; Triazines; Valproic Acid; Zonisamide | 1998 |
A mechanistic approach to antiepileptic drug interactions.
Topics: Acetates; Amines; Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Carbamazepine; Cyclohexanecarboxylic Acids; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Induction; Ethosuximide; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Glucuronosyltransferase; Humans; Lamotrigine; Mixed Function Oxygenases; Nipecotic Acids; Phenobarbital; Phenylcarbamates; Phenytoin; Propylene Glycols; Tiagabine; Topiramate; Triazines; Valproic Acid; Vigabatrin | 1998 |
[Neurotoxicity of anticonvulsants].
Topics: Anticonvulsants; Carbamazepine; Ethosuximide; Humans; Phenytoin; Primidone; Valproic Acid | 1999 |
[Childhood absence epilepsy(pyknolepsy)].
Topics: Child; Child, Preschool; Diagnosis, Differential; Epilepsy, Absence; Ethosuximide; Humans; Prognosis; Valproic Acid | 2002 |
[Juvenile absence epilepsy(JAE)].
Topics: Adolescent; Diagnosis, Differential; Epilepsy, Absence; Ethosuximide; Humans; Prognosis; Valproic Acid | 2002 |
[Epilepsy with myoclonic absences].
Topics: Child; Child, Preschool; Diagnosis, Differential; Drug Therapy, Combination; Electroencephalography; Epilepsies, Myoclonic; Ethosuximide; Humans; Infant; Prognosis; Syndrome; Valproic Acid | 2002 |
[Epilepsy with continuous spikes and waves during slow sleep].
Topics: Adolescent; Child; Clonazepam; Diagnosis, Differential; Drug Therapy, Combination; Electroencephalography; Epilepsy; Ethosuximide; Humans; Prognosis; Sleep; Valproic Acid | 2002 |
Absence seizures in children.
Topics: Acetates; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Epilepsy, Absence; Ethosuximide; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Triazines; Valproic Acid | 2002 |
Ethosuximide, sodium valproate or lamotrigine for absence seizures in children and adolescents.
Topics: Adolescent; Anticonvulsants; Child; Epilepsy, Absence; Ethosuximide; Humans; Lamotrigine; Randomized Controlled Trials as Topic; Triazines; Valproic Acid | 2003 |
Absence seizures in children.
Topics: Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Epilepsy, Absence; Ethosuximide; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Triazines; Valproic Acid | 2003 |
[Childhood and juvenile absence epilepsy. Treatment and prognosis].
Topics: Anticonvulsants; Child; Child Development; Child, Preschool; Cognition; Epilepsy, Absence; Ethosuximide; Evidence-Based Medicine; Humans; Lamotrigine; Prognosis; Triazines; Valproic Acid | 2004 |
Absence seizures in children.
Topics: Adolescent; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Epilepsy, Absence; Ethosuximide; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Triazines; Valproic Acid | 2004 |
A systematic review of treatment of typical absence seizures in children and adolescents with ethosuximide, sodium valproate or lamotrigine.
Topics: Anticonvulsants; Child; Epilepsy, Absence; Ethosuximide; Humans; Lamotrigine; Randomized Controlled Trials as Topic; Triazines; Valproic Acid | 2005 |
Absence seizures in children.
Topics: Adolescent; Amines; Anticonvulsants; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Epilepsy, Absence; Ethosuximide; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Triazines; Valproic Acid | 2005 |
Ethosuximide, sodium valproate or lamotrigine for absence seizures in children and adolescents.
Topics: Adolescent; Anticonvulsants; Child; Epilepsy, Absence; Ethosuximide; Humans; Lamotrigine; Randomized Controlled Trials as Topic; Triazines; Valproic Acid | 2005 |
Absence seizures in children.
Topics: Acute Disease; Anticonvulsants; Child; Epilepsy, Absence; Ethosuximide; Evidence-Based Medicine; Humans; Incidence; Quality of Life; Valproic Acid | 2008 |
New antiepileptic drugs: molecular targets.
Topics: Action Potentials; Animals; Anticonvulsants; Barbiturates; Carbamazepine; Clinical Trials as Topic; Drug Evaluation, Preclinical; Drug Monitoring; Electroshock; Epilepsy; Ethosuximide; gamma-Aminobutyric Acid; Humans; Molecular Structure; Neurotransmitter Transport Proteins; Phenytoin; Randomized Controlled Trials as Topic; Receptors, N-Methyl-D-Aspartate; Seizures; Structure-Activity Relationship; Synaptic Transmission; Treatment Outcome; Valproic Acid | 2009 |
Absence seizures in children.
Topics: Acute Disease; Anticonvulsants; Child; Epilepsy, Absence; Ethosuximide; Evidence-Based Medicine; Humans; Quality of Life; Seizures; Treatment Outcome; Valproic Acid | 2013 |
Antiepileptic dosing for critically ill adult patients receiving renal replacement therapy.
Topics: Acetamides; Acute Kidney Injury; Amines; Anticonvulsants; Carbamates; Critical Illness; Cyclohexanecarboxylic Acids; Dibenzazepines; Dose-Response Relationship, Drug; Ethosuximide; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lacosamide; Lamotrigine; Levetiracetam; Phenobarbital; Phenylcarbamates; Phenylenediamines; Phenytoin; Piracetam; Propylene Glycols; Renal Dialysis; Renal Replacement Therapy; Seizures; Topiramate; Triazines; Valproic Acid; Zonisamide | 2016 |
Ethosuximide, sodium valproate or lamotrigine for absence seizures in children and adolescents.
Topics: Adolescent; Anticonvulsants; Child; Epilepsy, Absence; Ethosuximide; Humans; Lamotrigine; Randomized Controlled Trials as Topic; Triazines; Valproic Acid | 2017 |
[Scientific evidence on treatment and prognosis of childhood absence epilepsy].
Topics: Anticonvulsants; Child; Cognition Disorders; Comorbidity; Electroencephalography; Epilepsy, Absence; Ethosuximide; Evidence-Based Medicine; Humans; Prognosis; Valproic Acid | 2017 |
Comparative efficacy of antiepileptic drugs in children and adolescents: A network meta-analysis.
Topics: Adolescent; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Resistant Epilepsy; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Ethosuximide; Hormones; Humans; Infant; Lamotrigine; Levetiracetam; Network Meta-Analysis; Nitriles; Odds Ratio; Piracetam; Pyridones; Spasms, Infantile; Treatment Outcome; Triazines; Valproic Acid | 2018 |
[Medicaments and oral healthcare. Proliferation of the gingiva].
Topics: Anticonvulsants; Carbamazepine; Cell Proliferation; Ethosuximide; Gingiva; Humans; Netherlands; Oral Hygiene; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 2018 |
A Practical Guide to Treatment of Childhood Absence Epilepsy.
Topics: Anticonvulsants; Child; Child, Preschool; Drug-Related Side Effects and Adverse Reactions; Electroencephalography; Epilepsy, Absence; Ethosuximide; Female; Humans; Lamotrigine; Male; Practice Guidelines as Topic; Seizures; Treatment Outcome; Valproic Acid | 2019 |
Ethosuximide, sodium valproate or lamotrigine for absence seizures in children and adolescents.
Topics: Adolescent; Anticonvulsants; Child; Epilepsy, Absence; Ethosuximide; Humans; Lamotrigine; Randomized Controlled Trials as Topic; Valproic Acid | 2019 |
Historical trend toward improved long-term outcome in childhood absence epilepsy.
Topics: Anticonvulsants; Child; Child, Preschool; Epilepsy, Absence; Ethosuximide; Female; History, 21st Century; Humans; Infant; Infant, Newborn; Longitudinal Studies; Male; Retrospective Studies; Treatment Outcome; Valproic Acid | 2019 |
A reappraisal of atypical absence seizures in children and adults: therapeutic implications.
Topics: Anticonvulsants; Epilepsy, Generalized; Ethosuximide; Humans; Lamotrigine; Lennox Gastaut Syndrome; ras GTPase-Activating Proteins; Valproic Acid | 2019 |
Ethosuximide, sodium valproate or lamotrigine for absence seizures in children and adolescents.
Topics: Adolescent; Anticonvulsants; Child; Epilepsy, Absence; Ethosuximide; Female; Humans; Lamotrigine; Male; Randomized Controlled Trials as Topic; Seizures; Treatment Failure; Valproic Acid | 2021 |
Breastfeeding while on treatment with antiseizure medications: a systematic review from the ILAE Women Task Force
Topics: Breast Feeding; Cannabidiol; Carbamazepine; Child; Clobazam; Clonazepam; Epilepsy; Ethosuximide; Everolimus; Felbamate; Female; Fenfluramine; Gabapentin; Humans; Infant; Lacosamide; Lamotrigine; Levetiracetam; Oxcarbazepine; Phenobarbital; Phenytoin; Prospective Studies; Tiagabine; Topiramate; Valproic Acid; Vigabatrin; Zonisamide | 2022 |
Psychobehavioural and Cognitive Adverse Events of Anti-Seizure Medications for the Treatment of Developmental and Epileptic Encephalopathies.
Topics: Autism Spectrum Disorder; Bromides; Cannabidiol; Clobazam; Cognition; Ethosuximide; Everolimus; Felbamate; Fenfluramine; Humans; Lacosamide; Lamotrigine; Levetiracetam; Pregabalin; Spasms, Infantile; Sulfides; Topiramate; Valproic Acid; Vigabatrin; Zinc Compounds; Zonisamide | 2022 |
Antiseizure medications for idiopathic generalized epilepsies: a systematic review and network meta-analysis.
Topics: Anticonvulsants; Child; Epilepsy, Generalized; Ethosuximide; Humans; Levetiracetam; Network Meta-Analysis; Randomized Controlled Trials as Topic; Seizures; Topiramate; Valproic Acid | 2023 |
16 trial(s) available for valproic acid and ethosuximide
| Article | Year |
|---|---|
Valproic acid (Depakene). A new anticonvulsant agent.
Topics: Animals; Child; Clinical Trials as Topic; Drug Evaluation; Drug Interactions; Epilepsies, Myoclonic; Epilepsy; Epilepsy, Absence; Ethosuximide; Humans; Platelet Aggregation; Valproic Acid | 1978 |
Discontinuation of antiepileptic drugs in children who have outgrown epilepsy: effects on cognitive function.
Topics: Adolescent; Anticonvulsants; Attention; Carbamazepine; Child; Cognition; Epilepsy; Ethosuximide; Humans; Memory, Short-Term; Phenytoin; Psychomotor Performance; Reaction Time; Valproic Acid | 1990 |
Evaluation of treatment in typical absence seizures. The roles of long-term EEG monitoring and ethosuximide.
Topics: Child; Child, Preschool; Clinical Trials as Topic; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy, Absence; Ethosuximide; Female; Humans; Male; Time Factors; Valproic Acid | 1985 |
Controlled and comparative trials with valproate: United States.
Topics: Adolescent; Adult; Child; Child, Preschool; Clinical Trials as Topic; Epilepsy; Epilepsy, Absence; Ethosuximide; Humans; Middle Aged; Phenytoin; Spasms, Infantile; United States; Valproic Acid | 1984 |
Valproic acid versus ethosuximide in the treatment of absence seizures.
Topics: Adolescent; Child; Child, Preschool; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Electroencephalography; Epilepsy, Absence; Ethosuximide; Evoked Potentials; Female; Humans; Male; Valproic Acid | 1982 |
Comparative study of ethosuximide and sodium valproate in the treatment of typical absence seizures (petit mal).
Topics: Acute Disease; Adolescent; Adult; Child; Child, Preschool; Clinical Trials as Topic; Epilepsy, Absence; Ethosuximide; Female; Humans; Male; Pancreatitis; Valproic Acid | 1982 |
[The enkorat treatment of infantile spasms and the Lennox-Gastaut syndrome].
Topics: Anticonvulsants; Carbamazepine; Child, Preschool; Clonazepam; Drug Therapy, Combination; Epilepsy; Ethosuximide; Female; Hemiplegia; Humans; Infant; Male; Remission Induction; Spasms, Infantile; Syndrome; Time Factors; Valproic Acid | 1994 |
Renal tubular dysfunction following treatment with anti-epileptic drugs.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cross-Sectional Studies; Epilepsy; Ethosuximide; Humans; Infant; Kidney Function Tests; Kidney Tubules; Phenytoin; Valproic Acid | 1994 |
Use of single sample clearance estimates of cytochrome P450 substrates to characterize human hepatic CYP status in vivo.
Topics: Administration, Oral; Adult; Antipyrine; Aryl Hydrocarbon Hydroxylases; Carbamazepine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Ethosuximide; Humans; Liver; Lorazepam; Male; Oxidoreductases, N-Demethylating; Phenobarbital; Phenytoin; Quinidine; Rifampin; Smoking; Theophylline; Valproic Acid | 1993 |
Pharmacokinetic interactions between lamotrigine and other antiepileptic drugs in children with intractable epilepsy.
Topics: Administration, Oral; Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clonazepam; Drug Administration Schedule; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Epilepsy; Ethosuximide; Female; Humans; Lamotrigine; Male; Phenobarbital; Treatment Outcome; Triazines; Valproic Acid | 1996 |
Beneficial effects of antiepileptic medication on absence seizures and cognitive functioning in children.
Topics: Adolescent; Anticonvulsants; Asthma; Attention; Child; Child, Preschool; Cognition; Discrimination, Psychological; Electroencephalography; Epilepsy, Absence; Ethosuximide; Female; Humans; Male; Matched-Pair Analysis; Memory; Motor Skills; Neuropsychological Tests; Prospective Studies; Reaction Time; Statistics, Nonparametric; Valproic Acid | 2007 |
Ethosuximide, valproic acid, and lamotrigine in childhood absence epilepsy.
Topics: Adolescent; Analysis of Variance; Anticonvulsants; Attention Deficit and Disruptive Behavior Disorders; Child; Child, Preschool; Double-Blind Method; Epilepsy, Absence; Ethosuximide; Female; Humans; Intention to Treat Analysis; Kaplan-Meier Estimate; Lamotrigine; Male; Seizures; Treatment Outcome; Triazines; Valproic Acid | 2010 |
Effects of fluoxetine on the anticonvulsant action of valproate and ethosuximide in mouse model of myoclonic convulsions.
Topics: Animals; Anticonvulsants; Antidepressive Agents, Second-Generation; Avoidance Learning; Convulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Epilepsies, Myoclonic; Ethosuximide; Fluorescent Antibody Technique; Fluoxetine; Male; Memory, Long-Term; Mice; Motor Activity; Pentylenetetrazole; Seizures; Selective Serotonin Reuptake Inhibitors; Valproic Acid | 2012 |
Ethosuximide, valproic acid, and lamotrigine in childhood absence epilepsy: initial monotherapy outcomes at 12 months.
Topics: Age Factors; Anticonvulsants; Child; Child, Preschool; Dose-Response Relationship, Drug; Double-Blind Method; Epilepsy, Absence; Ethosuximide; Female; Humans; Lamotrigine; Male; Treatment Outcome; Triazines; Valproic Acid | 2013 |
Pretreatment behavior and subsequent medication effects in childhood absence epilepsy.
Topics: Adolescent; Anticonvulsants; Checklist; Child; Child Behavior Disorders; Child, Preschool; Cross-Over Studies; Double-Blind Method; Electroencephalography; Epilepsy, Absence; Ethosuximide; Female; Follow-Up Studies; Humans; Lamotrigine; Male; Neuropsychological Tests; Outcome Assessment, Health Care; Triazines; Valproic Acid | 2017 |
Model-Informed Precision Dosing Guidance of Ethosuximide Developed from a Randomized Controlled Clinical Trial of Childhood Absence Epilepsy.
Topics: Anticonvulsants; Epilepsy, Absence; Ethosuximide; Humans; Seizures; Valproic Acid | 2023 |
228 other study(ies) available for valproic acid and ethosuximide
| Article | Year |
|---|---|
2-Phenyl-3H-imidazo[4,5-b]pyridine-3-acetamides as non-benzodiazepine anticonvulsants and anxiolytics.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Anxiety; Benzodiazepines; Binding, Competitive; Cerebral Cortex; gamma-Aminobutyric Acid; Imidazoles; Mice; Mice, Inbred ICR; Molecular Structure; Pyridines; Rats; Receptors, GABA-A; Seizures | 1991 |
Synthesis and anticonvulsant activity of 1-acyl-2-pyrrolidinone derivatives.
Topics: Animals; Anticonvulsants; Chemical Phenomena; Chemistry; gamma-Aminobutyric Acid; Male; Mice; Pyrrolidinones; Rats; Receptors, GABA-A; Seizures; Sleep; Structure-Activity Relationship | 1991 |
Synthesis and anticonvulsant activity of imidooxy derivatives.
Topics: Animals; Anticonvulsants; Chickens; Electroshock; Imides; Indicators and Reagents; Molecular Structure; Phthalimides; Reflex; Structure-Activity Relationship; Succinimides | 1991 |
Synthesis and anticonvulsant activity of 2-benzylglutarimides.
Topics: Animals; Anticonvulsants; Benzyl Compounds; Mice; Piperidines; Piperidones; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1990 |
Triazolines. 14. 1,2,3-Triazolines and triazoles, a new class of anticonvulsants. Drug design and structure-activity relationships.
Topics: Animals; Anticonvulsants; Electroshock; Mice; Seizures; Structure-Activity Relationship; Triazoles | 1988 |
Functionalized DL-amino acid derivatives. Potent new agents for the treatment of epilepsy.
Topics: Amino Acids; Animals; Anticonvulsants; Epilepsy; Magnetic Resonance Spectroscopy; Male; Mice; Seizures; Stereoisomerism; Structure-Activity Relationship | 1987 |
Synthesis and CLOGP correlation of imidooxy anticonvulsants.
Topics: Animals; Anticonvulsants; Chemical Phenomena; Chemistry, Physical; Crystallography, X-Ray; Electroshock; Male; Mice; Models, Molecular; Molecular Structure; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Seizures; Spiro Compounds; Structure-Activity Relationship | 1993 |
3,3-Dialkyl- and 3-alkyl-3-benzyl-substituted 2-pyrrolidinones: a new class of anticonvulsant agents.
Topics: Animals; Anticonvulsants; Humans; Magnetic Resonance Spectroscopy; Mice; Neurons; Pyrrolidinones | 1996 |
Synthesis and evaluation of N-(phenylacetyl)trifluoromethanesulfonamides as anticonvulsant agents.
Topics: Animals; Anticonvulsants; Body Weight; Cytochrome P-450 Enzyme System; Epilepsy; Mesylates; Mice; NADPH-Ferrihemoprotein Reductase; Organ Size; Oxidoreductases, O-Demethylating; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Sulfonamides | 1996 |
Synthesis and anticonvulsant activities of 3,3-dialkyl- and 3-alkyl-3-benzyl-2-piperidinones (delta-valerolactams) and hexahydro-2H-azepin-2-ones (epsilon-caprolactams).
Topics: Animals; Anticonvulsants; Bridged Bicyclo Compounds, Heterocyclic; Caprolactam; Electrophysiology; Ethosuximide; Mice; Phenobarbital; Piperidones; Rats; Valproic Acid | 1997 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity.
Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship | 2003 |
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.
Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution | 2005 |
Synthesis and anticonvulsant activity of sulfonamide derivatives-hydrophobic domain.
Topics: Animals; Anticonvulsants; Hydrophobic and Hydrophilic Interactions; Male; Mice; Mice, Inbred Strains; Rats; Rats, Sprague-Dawley; Rats, Wistar; Sulfonamides | 2007 |
Synthesis of some novel N4-(naphtha[1,2-d]thiazol-2-yl)semicarbazides as potential anticonvulsants.
Topics: Animals; Anticonvulsants; Brain Chemistry; Glutathione Peroxidase; Malondialdehyde; Mice; Motor Activity; Rats; Seizures; Semicarbazides; Structure-Activity Relationship; Superoxide Dismutase | 2009 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Novel, broad-spectrum anticonvulsants containing a sulfamide group: advancement of N-((benzo[b]thien-3-yl)methyl)sulfamide (JNJ-26990990) into human clinical studies.
Topics: Amides; Animals; Anticonvulsants; Carbonic Anhydrase II; Cell Line; Clinical Trials as Topic; Drug Evaluation, Preclinical; Female; Humans; Male; Mice; Rats; Sulfonamides; Thiophenes | 2009 |
Combating oxidative stress in epilepsy: design, synthesis, quantum chemical studies and anticonvulsant evaluation of 1-(substituted benzylidene/ethylidene)-4-(naphthalen-1-yl)semicarbazides.
Topics: Animals; Anticonvulsants; Antioxidants; Benzylidene Compounds; Drug Design; Electrons; Epilepsy; Male; Mice; Oxidative Stress; Quantum Theory; Semicarbazides | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Synthesis and anticonvulsant activity of ethyl 1-(2-arylhydrazinecarboxamido)-2,2-dimethylcyclopropanecarboxylate derivatives.
Topics: Animals; Anticonvulsants; Chemistry Techniques, Synthetic; Hydrazines; Male; Mice; Motor Activity; Rotarod Performance Test; Seizures | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Design, synthesis and anticonvulsant properties of new N-Mannich bases derived from 3-phenylpyrrolidine-2,5-diones.
Topics: Administration, Oral; Animals; Anticonvulsants; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Disease Models, Animal; Drug Design; Electroshock; Humans; Male; Mannich Bases; Mice; Microsomes, Liver; Motor Activity; Pentylenetetrazole; Protein Binding; Pyrrolidines; Rats; Rats, Sprague-Dawley; Seizures; Structure-Activity Relationship | 2013 |
Novel, broad-spectrum anticonvulsants containing a sulfamide group: pharmacological properties of (S)-N-[(6-chloro-2,3-dihydrobenzo[1,4]dioxin-2-yl)methyl]sulfamide (JNJ-26489112).
Topics: Absorption; Amides; Animals; Anticonvulsants; Dioxanes; Dogs; Drug Evaluation, Preclinical; Drug Resistance; Epilepsy; Female; Humans; Male; Mice; Rats; Sulfonamides | 2013 |
Seizure prevention by the naturally occurring phenols, carvacrol and thymol in a partial seizure-psychomotor model.
Topics: Animals; Anticonvulsants; Cymenes; Disease Models, Animal; Monoterpenes; Phenols; Psychomotor Performance; Seizures; Thymol | 2014 |
Design, synthesis and pharmacological evaluation of N-[4-(4-(alkyl/aryl/heteroaryl)-piperazin-1-yl)-phenyl]-carbamic acid ethyl ester derivatives as novel anticonvulsant agents.
Topics: Animals; Anticonvulsants; Carbamates; Drug Design; Electroshock; Epilepsy; Mice; Pentylenetetrazole; Piperazine; Piperazines; Seizures | 2015 |
Design, synthesis and biological evaluation of new hybrid anticonvulsants derived from N-benzyl-2-(2,5-dioxopyrrolidin-1-yl)propanamide and 2-(2,5-dioxopyrrolidin-1-yl)butanamide derivatives.
Topics: Amides; Animals; Anticonvulsants; Benzylamines; Convulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Design; Electroshock; Humans; Imidazoles; Male; Mice; Microsomes, Liver; Molecular Structure; Motor Activity; Pentylenetetrazole; Propionates; Pyrrolidines; Rotarod Performance Test; Seizures; Small Molecule Libraries; Structure-Activity Relationship | 2015 |
Design, synthesis, and anticonvulsant activity of new hybrid compounds derived from 2-(2,5-dioxopyrrolidin-1-yl)propanamides and 2-(2,5-dioxopyrrolidin-1-yl)butanamides.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Design; Electroshock; HEK293 Cells; Humans; Mice; Models, Molecular; Molecular Structure; Motor Activity; Piperazines; Seizures; Structure-Activity Relationship; Succinimides | 2015 |
Design, synthesis and biological activity of new amides derived from 3-methyl-3-phenyl-2,5-dioxo-pyrrolidin-1-yl-acetic acid.
Topics: Acetates; Amides; Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Design; Electroshock; Injections, Intraperitoneal; Mice; Molecular Structure; Pyrrolidines; Seizures | 2015 |
Synthesis of 2,6-dicarbethoxy-3,5-diaryltetrahydro-1,4-thiazine-1,1-dioxide derivatives as potent anticonvulsant agents.
Topics: Animals; Anticonvulsants; Crystallography, X-Ray; Cyclic S-Oxides; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Injections, Intraperitoneal; Mice; Models, Molecular; Molecular Structure; Pentylenetetrazole; Seizures; Structure-Activity Relationship; Thiazines | 2015 |
New hybrid molecules with anticonvulsant and antinociceptive activity derived from 3-methyl- or 3,3-dimethyl-1-[1-oxo-1-(4-phenylpiperazin-1-yl)propan-2-yl]pyrrolidine-2,5-diones.
Topics: Analgesics; Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Injections, Intraperitoneal; Mice; Molecular Structure; Pain; Pain Measurement; Pentylenetetrazole; Piperazines; Pyrrolidinones; Seizures | 2016 |
Synthesis, and anticonvulsant activity of new amides derived from 3-methyl- or 3-ethyl-3-methyl-2,5-dioxo-pyrrolidin-1-yl-acetic acids.
Topics: Amides; Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Mice; Molecular Structure; Pentylenetetrazole; Pyrrolidines; Seizures | 2016 |
Synthesis and evaluation of anticonvulsant properties of new N-Mannich bases derived from 3-(1-phenylethyl)- and 3-benzyl-pyrrolidine-2,5-dione.
Topics: Animals; Anticonvulsants; Calcium Channel Blockers; Calcium Channels, L-Type; GABA-A Receptor Antagonists; Mannich Bases; Mice; Piperazines; Pyrrolidines; Receptors, N-Methyl-D-Aspartate; Sodium Channel Blockers; Structure-Activity Relationship; Succinimides | 2016 |
Design, synthesis and anticonvulsant activity of new hybrid compounds derived from N-phenyl-2-(2,5-dioxopyrrolidin-1-yl)-propanamides and -butanamides.
Topics: Amides; Animals; Anticonvulsants; Calcium Channels; Drug Design; Humans; Injections, Intraperitoneal; Mice; Molecular Structure; Neurons; Pyrrolidines; Seizures | 2016 |
Synthesis and evaluation of anticonvulsant properties of new N-Mannich bases derived from pyrrolidine-2,5-dione and its 3-methyl-, 3-isopropyl, and 3-benzhydryl analogs.
Topics: Animals; Anticonvulsants; Mannich Bases; Mice; Pyrrolidines; Seizures | 2017 |
Modulating the Serotonin Receptor Spectrum of Pulicatin Natural Products.
Topics: Animals; Biological Products; Ligands; Mice; Molecular Structure; Receptors, Serotonin; Structure-Activity Relationship; Thiazolidines | 2017 |
Design, synthesis and anticonvulsant-analgesic activity of new
Topics: | 2017 |
Novel benzothiazole hydrazine carboxamide hybrid scaffolds as potential in vitro GABA AT enzyme inhibitors: Synthesis, molecular docking and antiepileptic evaluation.
Topics: Anticonvulsants; Hydrazines; Molecular Docking Simulation; Molecular Structure; Structure-Activity Relationship | 2019 |
[Adverse effects of anti-epileptic drugs].
Topics: Adrenocorticotropic Hormone; Anticonvulsants; Barbiturates; Carbamazepine; Diazepam; Epilepsy; Ethosuximide; Humans; Mephenytoin; Nitrazepam; Phenytoin; Primidone; Succinimides; Thiazines; Trimethadione; Valproic Acid | 1975 |
Effect of sodium valproate on plasma protein binding of diphenylhydantoin.
Topics: Animals; Blood Proteins; Brain; Drug Interactions; Ethosuximide; In Vitro Techniques; Injections, Intraperitoneal; Male; Phenytoin; Protein Binding; Rats; Thiazines; Valerates; Valproic Acid | 1977 |
Use of anticonvulsant drugs.
Topics: Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1979 |
Pharmacokinetics of drugs used for petit mal 'absence' epilepsy.
Topics: Administration, Oral; Benzodiazepinones; Biotransformation; Clonazepam; Drug Interactions; Epilepsy, Absence; Ethosuximide; Humans; Kinetics; Time Factors; Tissue Distribution; Valproic Acid | 1977 |
[Undesirable effects of antiepileptics].
Topics: Anticonvulsants; Barbiturates; Benzodiazepines; Carbamazepine; Ethosuximide; Humans; Hydantoins; Primidone; Valproic Acid | 1979 |
Choice of drug therapy in epilepsy.
Topics: Acetazolamide; Anticonvulsants; Benzodiazepines; Carbamazepine; Clonazepam; Epilepsy; Ethosuximide; Humans; Nitrazepam; Phenobarbital; Phenytoin; Valproic Acid | 1977 |
[Plasma levels of anticonvulsants. Experiences with routine plasma level determination of 6 different anticonvulsants].
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Drug Therapy, Combination; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1978 |
Long-term use of the major anticonvulsant drugs.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Drug Interactions; Epilepsy; Ethosuximide; Female; Humans; Phenobarbital; Phenytoin; Pregnancy; Primidone; Time Factors; Valproic Acid | 1978 |
Consecutive gas chromatographic determination of phenytoin, phenobarbital, primidone, phenylethylmalondiamide, carbamazepine, trimethadione, dimethadione, ethosuximide, and valproate from the same serum specimen.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Dimethadione; Ethosuximide; Phenobarbital; Phenylethylmalonamide; Phenytoin; Primidone; Trimethadione; Valproic Acid | 1978 |
Drugs for epilepsy.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Diazepam; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Status Epilepticus; Valproic Acid | 1979 |
Effects of valproate and ethosuximide on thalamocortical excitability.
Topics: Animals; Cats; Cerebral Cortex; Epilepsy; Ethosuximide; Thalamus; Valproic Acid | 1979 |
The use of antiepileptic drugs.
Topics: Anticonvulsants; Benzodiazepines; Carbamazepine; Drug Interactions; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1979 |
Simultaneous determination of di-n-propylacetic acid and ethosuximide in plasma by gas liquid chromatography.
Topics: Chromatography, Gas; Ethosuximide; Humans; Valproic Acid | 1979 |
[The serum concentration of anticonvulsants -- pharmacokinetic findings and practical therapeutic applications (author's transl)].
Topics: Antacids; Anticonvulsants; Biological Availability; Carbamazepine; Chromatography, Gas; Clonazepam; Dosage Forms; Ethosuximide; Half-Life; Humans; Immunoenzyme Techniques; Intestinal Absorption; Phenobarbital; Phenytoin; Primidone; Seizures; Valproic Acid | 1979 |
[Atypical petit mal status. Case contribution on diagnostic difficulties].
Topics: Adult; Cerebral Ventricle Neoplasms; Diagnostic Errors; Electroencephalography; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Ethosuximide; Humans; Male; Phenytoin; Tomography, X-Ray Computed; Valproic Acid | 1977 |
Efficacy testing of valproic acid compared to ethosuximide in monkey model: I. Dosage regimen design in the presence of diurnal oscillations.
Topics: Animals; Biopharmaceutics; Circadian Rhythm; Disease Models, Animal; Ethosuximide; Haplorhini; Macaca mulatta; Male; Seizures; Valerates; Valproic Acid | 1977 |
Efficacy testing of valproic acid compared to ethosuximide in monkey model: II. Seizure, EEG, and diurnal variations.
Topics: Animals; Circadian Rhythm; Disease Models, Animal; Electroencephalography; Ethosuximide; Haplorhini; Macaca mulatta; Male; Seizures; Valerates; Valproic Acid | 1977 |
[Measurement of the blood concentration of antiepileptic drugs. II Special cases].
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Clonazepam; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1975 |
Di-n-propylacetic acid--profile of anticonvulsant activity in mice.
Topics: Animals; Anticonvulsants; Bicuculline; Dose-Response Relationship, Drug; Electroshock; Ethosuximide; Female; Male; Mice; Pentylenetetrazole; Phenobarbital; Picrotoxin; Seizures; Strychnine; Trimethadione; Valerates; Valproic Acid | 1976 |
Proposals on antiepileptic pharmacotherapy for use in developing countries.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Clonazepam; Developing Countries; Diazepam; Epilepsy; Ethosuximide; Humans; Infant; Phenobarbital; Phenytoin; Valproic Acid | 1976 |
Influence of phenobarbital on ECoG phenomena induced by metrazol in rats during ontogenesis.
Topics: Aging; Animals; Cerebral Cortex; Clonazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Electrodes; Electroencephalography; Epilepsy; Ethosuximide; Injections, Intraperitoneal; Male; Pentylenetetrazole; Phenobarbital; Prohibitins; Rats; Rats, Wistar; Valproic Acid | 1992 |
The therapy of benign myoclonic epilepsy in infants.
Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Drug Therapy, Combination; Electroencephalography; Epilepsies, Myoclonic; Ethosuximide; Female; Humans; Infant; Male; Primidone; Valproic Acid | 1992 |
Mania and anticonvulsant therapy.
Topics: Attention Deficit Disorder with Hyperactivity; Bipolar Disorder; Child; Epilepsy, Absence; Ethosuximide; Humans; Male; Valproic Acid | 1992 |
Influence of antiepileptic drugs on sleep patterns.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Brain; Carbamazepine; Child; Child, Preschool; Drug Therapy, Combination; Electroencephalography; Epilepsy; Ethosuximide; Female; Humans; Long-Term Care; Male; Phenobarbital; Phenytoin; Retrospective Studies; Sleep Deprivation; Sleep Stages; Valproic Acid | 1991 |
Common epileptic syndromes in children.
Topics: Adolescent; Adrenocorticotropic Hormone; Carbamazepine; Child; Child, Preschool; Electroencephalography; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Ethosuximide; Female; Humans; Infant; Infant, Newborn; Male; Spasms, Infantile; Valproic Acid | 1991 |
Effect of antiepileptic drugs valproic acid, carbamazepine and ethosuccimide on exploratory behaviour in mice.
Topics: Analysis of Variance; Animals; Carbamazepine; Ethosuximide; Exploratory Behavior; Female; Male; Mice; Valproic Acid | 1991 |
[Pellagra in anticonvulsive therapy].
Topics: Adult; Anticonvulsants; Drug Therapy, Combination; Epilepsy; Ethosuximide; Female; Humans; Intellectual Disability; Pellagra; Phenytoin; Photosensitivity Disorders; Valproic Acid; Vitamins | 1990 |
Development of tolerance to the anticonvulsant effect of valproate but not to ethosuximide in a rat model of absence epilepsy.
Topics: Animals; Anticonvulsants; Drug Tolerance; Electroencephalography; Epilepsy, Absence; Ethosuximide; Female; Rats; Rats, Inbred Strains; Valproic Acid | 1990 |
Simultaneous determination of six antiepileptic drugs by capillary gas chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Ethosuximide; Humans; Hydroxides; Phenobarbital; Phenytoin; Potassium; Potassium Compounds; Primidone; Valproic Acid | 1990 |
[A case of adult-onset spike-wave stupor associated with hypoparathyroidism and hyperostosis frontalis interna (HFI)].
Topics: Adult; Electroencephalography; Epilepsy, Absence; Ethosuximide; Female; Humans; Hyperostosis Frontalis Interna; Hypoparathyroidism; Tomography, X-Ray Computed; Valproic Acid; Vitamin D | 1990 |
Rapid anti-epileptic drug assay.
Topics: Anticonvulsants; Carbamazepine; Child; Dose-Response Relationship, Drug; Epilepsy; Ethosuximide; Humans; Patient Compliance; Phenobarbital; Phenytoin; Valproic Acid | 1990 |
Influence of calcium channel inhibitors upon the anticonvulsant efficacy of common antiepileptics against pentylenetetrazol-induced convulsions in mice.
Topics: Animals; Anticonvulsants; Calcium Channel Blockers; Diltiazem; Drug Therapy, Combination; Ethosuximide; Male; Mice; Nifedipine; Pentylenetetrazole; Phenobarbital; Reference Values; Seizures; Valproic Acid; Verapamil | 1990 |
[Plasma determination of 7 common drugs by high performance liquid chromatography].
Topics: Anticonvulsants; Bronchodilator Agents; Caffeine; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Phenobarbital; Phenytoin; Theophylline; Valproic Acid | 1989 |
Gamma-hydroxybutyrate stimulation of the formation of cyclic GMP and inositol phosphates in rat hippocampal slices.
Topics: Animals; Cyclic GMP; Ethosuximide; Hippocampus; Hydroxybutyrates; Inositol Phosphates; Kinetics; Nalorphine; Naloxone; Pentazocine; Rats; Rats, Inbred Strains; Sodium Oxybate; Sugar Phosphates; Trimethadione; Valproic Acid | 1989 |
Characterization of ethosuximide reduction of low-threshold calcium current in thalamic neurons.
Topics: Animals; Calcium Channels; Dimethadione; Ethosuximide; Guinea Pigs; Neurons; Rats; Thalamus; Valproic Acid | 1989 |
Effect of anticonvulsants on pentylenetetrazol-induced power spectrum changes in electroencephalograms in rats.
Topics: Animals; Anticonvulsants; Cerebral Cortex; Cyclic AMP; Electroencephalography; Ethosuximide; Male; Pentylenetetrazole; Phenobarbital; Rats; Rats, Inbred Strains; Seizures; Valproic Acid | 1987 |
Evidence for involvement of the astrocytic benzodiazepine receptor in the mechanism of action of convulsant and anticonvulsant drugs.
Topics: Animals; Anticonvulsants; Astrocytes; Barbiturates; Benzodiazepinones; Brain; Carbamazepine; Cells, Cultured; Convulsants; Diazepam; Ethosuximide; Mice; Neurons; Pentylenetetrazole; Phenobarbital; Picrotoxin; Receptors, GABA-A; Sesterterpenes; Trimethadione; Valproic Acid | 1988 |
Influence of ethosuximide and dipropylacetate on metrazol-induced electrocorticographic changes during ontogenesis in rats.
Topics: Animals; Brain; Electroencephalography; Ethosuximide; Pentylenetetrazole; Rats; Rats, Inbred Strains; Theta Rhythm; Valproic Acid | 1986 |
Chronic effects of ethosuximide, phenytoin, clonazepam, and valproic acid on the delayed-matching-to-sample performance of pigeons.
Topics: Animals; Anticonvulsants; Clonazepam; Columbidae; Ethosuximide; Phenytoin; Psychomotor Performance; Time Factors; Valproic Acid | 1986 |
Sodium valproate, but not ethosuximide, produces use- and voltage-dependent limitation of high frequency repetitive firing of action potentials of mouse central neurons in cell culture.
Topics: Action Potentials; Animals; Carbamazepine; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Electric Stimulation; Ethosuximide; gamma-Aminobutyric Acid; Magnesium; Mice; Neurons; Phenytoin; Seizures; Sodium; Spinal Cord; Valproic Acid | 1986 |
Behavioral toxicity of chronic ethosuximide and sodium valproate treatment in the epileptic baboon, Papio papio.
Topics: Animals; Conditioning, Operant; Dose-Response Relationship, Drug; Epilepsy; Ethosuximide; Female; Male; Papio; Time Factors; Valproic Acid | 1986 |
Chronic effects of clonazepam, phenytoin, ethosuximide, and valproic acid on learning in pigeons as assayed by a repeated acquisition procedure.
Topics: Animals; Benzodiazepinones; Clonazepam; Columbidae; Dose-Response Relationship, Drug; Drug Tolerance; Ethosuximide; Learning; Phenytoin; Valproic Acid | 1986 |
Effects of anticonvulsant drugs on substantia nigra pars reticulata neurons.
Topics: Animals; Anticonvulsants; Carbamazepine; Clonazepam; Dose-Response Relationship, Drug; Ethosuximide; Male; Neurons; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Substantia Nigra; Trimethadione; Valproic Acid | 1986 |
Improved procedure for simultaneous determination of sodium valproate and ethosuximide in serum by gas liquid chromatography.
Topics: Chromatography, Gas; Ethosuximide; Humans; Valproic Acid | 1986 |
[Modification of psychophysical performance of the human by anticonvulsants].
Topics: Anticonvulsants; Arousal; Carbamazepine; Diazepam; Epilepsy; Ethosuximide; Humans; Mental Processes; Phenobarbital; Psychological Tests; Psychomotor Performance; Valproic Acid | 1987 |
Effect of anticonvulsant drugs on gamma-hydroxybutyrate release from hippocampal slices: inhibition by valproate and ethosuximide.
Topics: Animals; Ethosuximide; Hippocampus; Hydroxybutyrates; Pentobarbital; Potassium; Rats; Rats, Inbred Strains; Sodium Oxybate; Trimethadione; Valproic Acid; Verapamil; Veratridine | 1987 |
Combination of valproate and ethosuximide: antiepileptic and neurotoxic interaction.
Topics: Animals; Brain; Drug Synergism; Drug Therapy, Combination; Epilepsy; Ethosuximide; Female; Mice; Mice, Inbred ICR; Valproic Acid | 1988 |
Pharmacologic interactions between valproate and other drugs.
Topics: Anticonvulsants; Carbamazepine; Drug Interactions; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1988 |
Effect of stimulus intensity on the profile of anticonvulsant activity of phenytoin, ethosuximide and valproate.
Topics: Animals; Anticonvulsants; Bicuculline; Electroshock; Ethosuximide; Male; Mice; Pentylenetetrazole; Phenytoin; Picrotoxin; Seizures; Valproic Acid | 1985 |
Antiepileptic drug evaluation in a new animal model: spontaneous petit mal epilepsy in the rat.
Topics: Animals; Anticonvulsants; Carbamazepine; Diazepam; Disease Models, Animal; Drug Evaluation, Preclinical; Electroencephalography; Epilepsy, Absence; Ethosuximide; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Trimethadione; Valproic Acid | 1985 |
Anticonvulsant drugs and the genetically epilepsy-prone rat.
Topics: Acoustic Stimulation; Amitriptyline; Animals; Anticonvulsants; Carbamazepine; Desipramine; Disease Models, Animal; Epilepsy; Ethosuximide; Imipramine; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Seizures; Valproic Acid | 1985 |
Pharmacological evaluation of various metabolites and analogues of valproic acid. Anticonvulsant and toxic potencies in mice.
Topics: Animals; Anticonvulsants; Chemical Phenomena; Chemistry; Disease Models, Animal; Epilepsy; Ethosuximide; Male; Mice; Structure-Activity Relationship; Valproic Acid | 1985 |
Effects of phenobarbital, clonazepam, valproic acid, ethosuximide, and phenytoin on the delayed matching-to-sample performance of pigeons.
Topics: Animals; Anticonvulsants; Clonazepam; Columbidae; Conditioning, Psychological; Dose-Response Relationship, Drug; Ethosuximide; Memory; Phenobarbital; Phenytoin; Valproic Acid | 1985 |
Blockade of "antiabsence" activity of sodium valproate by THIP in rats with petit mal-like seizures. Comparison with ethosuximide.
Topics: Animals; Epilepsy, Absence; Ethosuximide; GABA Antagonists; Injections; Isoxazoles; Male; Oxazoles; Rats; Rats, Inbred Strains; Valproic Acid | 1985 |
Longterm follow-up of childhood epilepsy with absences. I. Epilepsy with absences at onset.
Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Epilepsy; Epilepsy, Absence; Ethosuximide; Female; Follow-Up Studies; Humans; Infant; Male; Middle Aged; Phenobarbital; Prognosis; Time Factors; Valproic Acid | 1985 |
Longterm follow-up of childhood epilepsy with absences. II. Absence-epilepsy with initial grand mal.
Topics: Adolescent; Adult; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Ethosuximide; Female; Follow-Up Studies; Humans; Male; Middle Aged; Prognosis; Time Factors; Valproic Acid | 1985 |
Effects of valproic acid and ethosuximide on the responding of pigeons maintained under a multiple fixed-ratio fixed-interval schedule of food delivery.
Topics: Animals; Columbidae; Conditioning, Operant; Dose-Response Relationship, Drug; Ethosuximide; Reinforcement Schedule; Time Factors; Valproic Acid | 1985 |
Monitoring: the most important role of the pediatrician.
Topics: Activities of Daily Living; Anticonvulsants; Carbamazepine; Child, Preschool; Environmental Monitoring; Epilepsy; Ethosuximide; Humans; Monitoring, Physiologic; Phenobarbital; Phenytoin; Referral and Consultation; Social Support; Valproic Acid | 1985 |
[Simple gas chromatography determination of valproic acid and ethosuximide in serum].
Topics: Chromatography, Gas; Ethosuximide; Humans; Quality Control; Time Factors; Valproic Acid | 1985 |
Pyknoleptic petit mal.
Topics: Adolescent; Age Factors; Animals; Bibliographies as Topic; Child; Child, Preschool; Clonazepam; Diagnosis, Differential; Electroencephalography; Epilepsy, Absence; Ethosuximide; Female; History, 18th Century; History, 19th Century; History, 20th Century; Humans; Prognosis; Valproic Acid | 1985 |
Seizure control following administration of anticonvulsant drugs in the quaking mouse.
Topics: Animals; Anticonvulsants; Carbamazepine; Diazepam; Ethosuximide; Mice; Mice, Inbred C57BL; Mice, Quaking; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 1985 |
Excitable channel currents and gating times in the presence of anticonvulsants ethosuximide and valproate.
Topics: Animals; Decapodiformes; Dose-Response Relationship, Drug; Ethosuximide; Ion Channels; Kinetics; Mathematics; Potassium; Sodium; Valproic Acid | 1984 |
Diphenylhydantoin substrate induced difference spectra: inhibition by other anticonvulsant drugs.
Topics: Animals; Anticonvulsants; Ethosuximide; In Vitro Techniques; Kinetics; Male; Microsomes, Liver; Phenobarbital; Phenytoin; Rats; Spectrophotometry; Thiazines; Valproic Acid | 1980 |
Changes in regional brain levels of amino acid putative neurotransmitters after prolonged treatment with the anticonvulsant drugs diphenylhydantoin, phenobarbitone, sodium valproate, ethosuximide, and sulthiame in the rat.
Topics: Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Brain; Ethosuximide; gamma-Aminobutyric Acid; Glutamates; Male; Neurotransmitter Agents; Organ Specificity; Phenobarbital; Phenytoin; Rats; Taurine; Thiazines; Valproic Acid | 1981 |
Choice of anticonvulsants in epilepsy.
Topics: Adult; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Carbamazepine; Child; Child, Preschool; Epilepsy; Ethosuximide; Follow-Up Studies; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1981 |
The influence of antiepileptic drugs on the electroencephalogram: a review of controlled clinical studies.
Topics: Anti-Anxiety Agents; Anticonvulsants; Brain; Carbamazepine; Clonazepam; Electroencephalography; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1982 |
Topographic approaches in human quantitative pharmaco-electroencephalography.
Topics: Anti-Anxiety Agents; Benzodiazepines; Dose-Response Relationship, Drug; Electroencephalography; Ethosuximide; Evoked Potentials; Flurazepam; Humans; Levetiracetam; Piracetam; Psychotropic Drugs; Valproic Acid | 1983 |
Metabolic interactions of phenytoin in the rat: effect of coadministration with the anticonvulsant drugs sodium valproate, sulthiame, ethosuximide or phenobarbital.
Topics: Animals; Anticonvulsants; Brain; Drug Interactions; Ethosuximide; Male; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Thiazines; Valproic Acid | 1984 |
Pharmacokinetics of antiepileptic drugs.
Topics: Adult; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Carbamazepine; Child; Child, Preschool; Drug Interactions; Epilepsy; Ethosuximide; Female; Half-Life; Humans; Infant; Infant, Newborn; Intestinal Absorption; Kinetics; Male; Metabolic Clearance Rate; Phenobarbital; Phenytoin; Pregnancy; Primidone; Protein Binding; Valproic Acid | 1983 |
Antiepileptic agents affect hypothalamic beta-endorphin concentrations.
Topics: Animals; Anticonvulsants; beta-Endorphin; Endorphins; Ethosuximide; Hypothalamus; Kinetics; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Somatostatin; Substance P; Valproic Acid | 1984 |
Anticonvulsants specific for petit mal antagonize epileptogenic effect of leucine enkephalin.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Endorphins; Enkephalins; Epilepsy, Absence; Ethosuximide; Male; Rats; Receptors, Opioid; Seizures; Trimethadione; Valproic Acid | 1980 |
Therapeutic monitoring of serum antiepileptic drug levels.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Ethosuximide; Humans; Laboratories; Monitoring, Physiologic; Phenobarbital; Phenytoin; Primidone; Time Factors; Valproic Acid | 1983 |
Valproate-ethosuximide combination therapy for refractory absence seizures.
Topics: Adolescent; Child; Drug Therapy, Combination; Epilepsy, Absence; Ethosuximide; Female; Humans; Male; Middle Aged; Valproic Acid | 1983 |
[Pharmacotherapy of epilepsy--current problems and controversies].
Topics: Adolescent; Adult; Carbamazepine; Child; Child, Preschool; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epilepsy, Post-Traumatic; Epilepsy, Tonic-Clonic; Ethosuximide; Female; Humans; Infant; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Primidone; Seizures, Febrile; Status Epilepticus; Valproic Acid | 1983 |
Some clinical and EEG aspects of benign juvenile myoclonic epilepsy.
Topics: Adolescent; Carbamazepine; Child; Child, Preschool; Drug Combinations; Electroencephalography; Epilepsies, Myoclonic; Ethosuximide; Female; Humans; Male; Phenytoin; Valproic Acid | 1984 |
Unnecessary polypharmacy in patients with frequent seizures.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Clonazepam; Drug Therapy, Combination; Epilepsy; Ethosuximide; Female; Humans; Male; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1984 |
Valproic acid-ethosuximide interaction: a pharmacokinetic study.
Topics: Adolescent; Adult; Drug Interactions; Ethosuximide; Female; Humans; Kinetics; Male; Middle Aged; Valproic Acid | 1984 |
Anticonvulsant potency of common antiepileptic drugs in the gerbil.
Topics: Animals; Anticonvulsants; Carbamazepine; Diazepam; Ethosuximide; Female; Gerbillinae; Male; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 1983 |
Absence seizures: valproate or ethosuximide?
Topics: Adolescent; Child; Child, Preschool; Drug Therapy, Combination; Electroencephalography; Epilepsy, Absence; Ethosuximide; Evoked Potentials; Female; Follow-Up Studies; Humans; Infant; Male; Nitrazepam; Valproic Acid | 1983 |
Psychiatric complications of absence therapy and their relation to alteration of sleep.
Topics: Delusions; Depression; Epilepsy, Absence; Ethosuximide; Female; Humans; Hypochondriasis; Hysteria; Male; Paranoid Disorders; Sleep; Valproic Acid | 1984 |
Effect of anticonvulsant drugs on thalamo-cortical and hippocampo-cortical self-sustained after-discharges in the rat.
Topics: Animals; Anticonvulsants; Carbamazepine; Cerebral Cortex; Electric Stimulation; Electroencephalography; Epilepsy; Ethosuximide; Hippocampus; Kindling, Neurologic; Male; Phenytoin; Rats; Rats, Inbred Strains; Thalamus; Valproic Acid | 1984 |
The effects of various antiepileptic drugs on E-shock-induced amnesia in mice: dissociability of effects on convulsions and effects on memory.
Topics: Amnesia; Animals; Anticonvulsants; Carbamazepine; Clonazepam; Electroshock; Ethosuximide; Humans; Male; Mice; Phenobarbital; Phenytoin; Valproic Acid | 1984 |
Effects of anticonvulsants on learning: performance of pigeons under a repeated acquisition procedure when exposed to phenobarbital, clonazepam, valproic acid, ethosuximide and phenytoin.
Topics: Animals; Anticonvulsants; Clonazepam; Columbidae; Dose-Response Relationship, Drug; Ethosuximide; Learning; Phenobarbital; Phenytoin; Valproic Acid | 1984 |
Nonsedative regimens in the treatment of epilepsy.
Topics: Carbamazepine; Epilepsy; Ethosuximide; Humans; Phenytoin; Seizures; Valproic Acid | 1983 |
[Plasma levels of antiepileptic agents in the treatment of epilepsy].
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clonazepam; Drug Interactions; Drug Therapy, Combination; Epilepsy; Ethosuximide; Female; Humans; Infant; Infant, Newborn; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1984 |
Effect of antiepileptic drugs on metrazol convulsions during ontogenesis in the rat.
Topics: Age Factors; Animals; Anticonvulsants; Clonazepam; Ethosuximide; Male; Pentylenetetrazole; Rats; Seizures; Valproic Acid | 1981 |
Antiabsence drugs and inhibitory pathways.
Topics: Animals; Anticonvulsants; Cats; Cerebral Ventricles; Epilepsy, Absence; Ethosuximide; Imipramine; Neural Inhibition; Neural Pathways; Trimethadione; Valproic Acid | 1980 |
Simple, rapid procedure for the determination of valproate and ethosuximide in plasma by gas-liquid chromatography.
Topics: Chromatography, Gas; Ethosuximide; Humans; Valproic Acid | 1980 |
Comparative effects of two commercially available blood collection tubes on plasma concentrations of drugs.
Topics: Acebutolol; Blood Specimen Collection; Carbamazepine; Diazepam; Digoxin; Ethosuximide; Humans; Nordazepam; Penbutolol; Pharmaceutical Preparations; Propranolol; Quinidine; Salicylates; Time Factors; Valproic Acid; Warfarin | 1980 |
[Comparative effectiveness of antiepileptic preparations in the treatment of patients with trigeminal neuralgia].
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Ethosuximide; Follow-Up Studies; Humans; Morpholines; Pyrrolidinones; Trigeminal Neuralgia; Valproic Acid | 1980 |
Simplified simultaneous determination of valproic acid and ethosuximide in serum by gas-liquid chromatography.
Topics: Chromatography, Gas; Epilepsy; Ethosuximide; Humans; Valproic Acid | 1980 |
[A gaschromatographic method for the simultaneous determination of ethosuximide and valproate in serum (author's transl)].
Topics: Chromatography, Gas; Ethosuximide; Humans; Microchemistry; Valproic Acid | 1980 |
Valproic acid and ethosuximide interaction.
Topics: Adolescent; Adult; Child; Child, Preschool; Drug Interactions; Drug Therapy, Combination; Epilepsy, Absence; Ethosuximide; Female; Humans; Male; Valproic Acid | 1980 |
Improved extraction of valproic acid from serum before chromatography.
Topics: Chromatography, Gas; Emulsions; Ethosuximide; Humans; Valproic Acid | 1980 |
Effect of anticonvulsant drugs on inhibitory and excitatory pathways.
Topics: Animals; Carbamazepine; Cats; Electric Stimulation; Ethosuximide; Maxillary Nerve; Neural Pathways; Phenytoin; Time Factors; Valproic Acid | 1981 |
Drug treatment of epilepsy.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Electroencephalography; Epilepsy; Ethosuximide; Female; Humans; Phenobarbital; Phenytoin; Pregnancy; Primidone; Seizures; Substance Withdrawal Syndrome; Valproic Acid | 1981 |
Quantitative evaluation of anticonvulsant effects on penicillin-induced spike foci in cats.
Topics: Animals; Anticonvulsants; Carbamazepine; Cats; Electroencephalography; Ethosuximide; Penicillins; Phenytoin; Seizures; Valproic Acid | 1981 |
Simplified gas chromatography of valproic acid and ethosuximide.
Topics: Chromatography, Gas; Ethosuximide; Humans; Reference Values; Valproic Acid | 1982 |
Rapid and simple GLC determination of valproic acid and ethosuximide in plasma of epileptic patients.
Topics: Chromatography, Gas; Epilepsy; Ethosuximide; Humans; Valproic Acid | 1982 |
Ethosuximide kinetics: possible interaction with valproic acid.
Topics: Adult; Drug Interactions; Ethosuximide; Female; Humans; Kinetics; Male; Time Factors; Valproic Acid | 1982 |
Effect of anticonvulsant drugs on kainic acid-induced epileptiform activity.
Topics: Animals; Anticonvulsants; Diazepam; Electroencephalography; Ethosuximide; Guinea Pigs; Hippocampus; Kainic Acid; Phenobarbital; Phenytoin; Pyrrolidines; Rats; Rats, Inbred Strains; Seizures; Valproic Acid | 1982 |
Effect of sodium valproate and ethosuximide on phenobarbital plasma protein binding.
Topics: Binding, Competitive; Blood Proteins; Ethosuximide; Humans; Phenobarbital; Valproic Acid | 1982 |
[Clinical evaluation of certain modern antiepileptic preparations].
Topics: Anticonvulsants; Automatism; Carbamazepine; Child; Clonazepam; Diencephalon; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Ethosuximide; Humans; Syndrome; Valproic Acid | 1982 |
Practical considerations in anticonvulsant therapy--Part 2.
Topics: Anticonvulsants; Benzodiazepines; Cost Control; Epilepsy; Ethosuximide; Humans; Monitoring, Physiologic; Patient Compliance; Patient Education as Topic; Pharmacists; Phenobarbital; Phenytoin; Primidone; Role; Valproic Acid | 1995 |
How long to treat childhood onset absence epilepsy.
Topics: Anticonvulsants; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Electroencephalography; Epilepsy, Absence; Ethosuximide; Evoked Potentials; Female; Humans; Male; Monitoring, Physiologic; Valproic Acid | 1995 |
Effect of antiepileptic drugs on absence-like seizures in the tremor rat.
Topics: Animals; Anticonvulsants; Data Interpretation, Statistical; Drug Therapy, Combination; Electroencephalography; Epilepsy, Absence; Ethosuximide; Female; Injections, Intraperitoneal; Male; Phenobarbital; Phenytoin; Rats; Rats, Inbred WKY; Rats, Mutant Strains; Seizures; Time Factors; Trimethadione; Valproic Acid | 1995 |
Valproic acid and ethosuximide slow the onset of maximal dentate activation in the rat hippocampus.
Topics: Animals; Dose-Response Relationship, Drug; Ethosuximide; Hippocampus; Male; Rats; Rats, Sprague-Dawley; Seizures; Time Factors; Valproic Acid | 1994 |
Epilepsy treatment in The Netherlands. Comparison of matched groups of two medical centres.
Topics: Adolescent; Adult; Carbamazepine; Diazepam; Epilepsy; Ethosuximide; Female; gamma-Aminobutyric Acid; Humans; Male; Netherlands; Phenobarbital; Phenytoin; Primidone; Quality of Health Care; Statistics, Nonparametric; Treatment Outcome; Valproic Acid; Vigabatrin | 1994 |
Is the site of action of ethosuximide in the hindbrain?
Topics: Animals; Anticonvulsants; Brain Stem; Clonazepam; Decerebrate State; Electrocardiography; Electroencephalography; Ethosuximide; Male; Pentylenetetrazole; Rats; Rats, Wistar; Rhombencephalon; Seizures; Valproic Acid | 1994 |
[Absence seizures in adulthood: four cases].
Topics: Adult; Age Factors; Age of Onset; Drug Therapy, Combination; Electroencephalography; Epilepsy, Absence; Epilepsy, Generalized; Ethosuximide; Female; Humans; Male; Middle Aged; Polysomnography; Sleep; Stress, Psychological; Valproic Acid | 1994 |
The use of antiepileptic drug levels in children: a survey of Canadian pediatric neurologists.
Topics: Adolescent; Anticonvulsants; Attitude of Health Personnel; Carbamazepine; Child; Epilepsy; Ethosuximide; Female; Humans; Male; Phenobarbital; Valproic Acid | 1993 |
A new chronic model of spontaneous nonconvulsive generalized seizures.
Topics: 4-Butyrolactone; Animals; Cerebral Cortex; Corpus Callosum; Electroencephalography; Epilepsy, Absence; Epilepsy, Generalized; Ethosuximide; Evoked Potentials; Injections, Intraperitoneal; Male; Phenytoin; Rats; Rats, Wistar; Seizures; Sodium Oxybate; Valproic Acid | 1993 |
Antiepileptic drugs--their effects on kindled seizures and kindling-induced learning impairments.
Topics: Animals; Anticonvulsants; Avoidance Learning; Cognition; Dose-Response Relationship, Drug; Ethosuximide; Kindling, Neurologic; Learning Disabilities; Male; Pentylenetetrazole; Phenobarbital; Rats; Rats, Wistar; Seizures; Valproic Acid | 1995 |
Increasing-current electroshock seizure test: a new method for assessment of anti- and pro-convulsant activities of drugs in mice.
Topics: Analgesics, Opioid; Animals; Anticonvulsants; Carbamazepine; Convulsants; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation; Drug Interactions; Ear; Electrodes; Electroshock; Ethosuximide; Injections, Intravenous; Male; Mice; Morphine; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 1996 |
Influence of nicardipine, nimodipine and flunarizine on the anticonvulsant efficacy of antiepileptics against pentylenetetrazol in mice.
Topics: Animals; Anticonvulsants; Calcium Channel Blockers; Clonazepam; Drug Interactions; Ethosuximide; Flunarizine; Male; Mice; Mice, Inbred Strains; Motor Activity; Nicardipine; Nimodipine; Pentylenetetrazole; Random Allocation; Seizures; Valproic Acid | 1996 |
Interspecies scaling: predicting pharmacokinetic parameters of antiepileptic drugs in humans from animals with special emphasis on clearance.
Topics: Animals; Anticonvulsants; Diazepam; Ethosuximide; Half-Life; Humans; Models, Biological; Species Specificity; Valproic Acid | 1996 |
Clinical case report: multiple idiosyncratic adverse effects of antiepileptic drugs in trisomy 9p.
Topics: Adult; Anticonvulsants; Brain; Carbamazepine; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, Pair 9; Diagnostic Errors; Electroencephalography; Epilepsy, Generalized; Ethosuximide; Female; Hodgkin Disease; Humans; Intellectual Disability; Lupus Erythematosus, Systemic; Magnetic Resonance Imaging; Myoclonus; Phenytoin; Pseudolymphoma; Trisomy; Valproic Acid | 1996 |
Binding characteristics of gamma-hydroxybutyric acid as a weak but selective GABAB receptor agonist.
Topics: Animals; Anticonvulsants; Baclofen; Binding, Competitive; Brain Chemistry; Ethosuximide; GABA Agonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Guanylyl Imidodiphosphate; In Vitro Techniques; Male; Organophosphorus Compounds; Radioligand Assay; Rats; Rats, Wistar; Receptors, GABA-B; Sodium Oxybate; Valproic Acid | 1997 |
Influence of ethosuximide on valproic acid serum concentrations.
Topics: Adolescent; Child; Child, Preschool; Drug Interactions; Ethosuximide; Female; Humans; Male; Valproic Acid | 1997 |
Prognostic factors for childhood and juvenile absence epilepsies.
Topics: Adolescent; Adult; Age of Onset; Anticonvulsants; Child; Child, Preschool; Drug Therapy, Combination; Electroencephalography; Epilepsy, Absence; Ethosuximide; Female; Follow-Up Studies; Humans; Male; Phenobarbital; Prognosis; Retrospective Studies; Time Factors; Valproic Acid | 1997 |
gamma-Hydroxybutyrate conversion into GABA induces displacement of GABAB binding that is blocked by valproate and ethosuximide.
Topics: 4-Aminobutyrate Transaminase; Animals; Binding Sites; Brain; Enzyme Inhibitors; Ethosuximide; gamma-Aminobutyric Acid; Hydroxybutyrate Dehydrogenase; In Vitro Techniques; Male; Rats; Rats, Wistar; Sodium Oxybate; Valproic Acid | 1997 |
[The efficacy of the valproic acid-ethosuximide combination in the continuous slow point wave syndrome during sleep].
Topics: Anticonvulsants; Brain; Child; Electroencephalography; Epilepsy, Generalized; Ethosuximide; Female; Humans; Sleep, REM; Tomography, Emission-Computed, Single-Photon; Valproic Acid | 1997 |
Additive anticonvulsant effect of flunarizine and sodium valproate on electroshock and chemoshock induced seizures in mice.
Topics: Animals; Anticonvulsants; Carbamazepine; Disease Models, Animal; Drug Interactions; Drug Synergism; Drug Therapy, Combination; Electroshock; Ethosuximide; Flunarizine; Male; Mice; Motor Activity; Pentylenetetrazole; Phenytoin; Seizures; Valproic Acid | 1998 |
Effects of polytherapy compared with monotherapy in antiepileptic drugs: an animal study.
Topics: Animals; Anticonvulsants; Ataxia; Behavior, Animal; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Ethosuximide; Hand Strength; Male; Nervous System Diseases; Rats; Rats, Wistar; Valproic Acid | 1999 |
N(G)-nitro-L-arginine impairs the anticonvulsive action of ethosuximide against pentylenetetrazol.
Topics: Animals; Anticonvulsants; Arginine; Convulsants; Diazepam; Drug Interactions; Enzyme Inhibitors; Ethosuximide; Male; Mice; Nitroarginine; Pentylenetetrazole; Phenobarbital; Psychomotor Performance; Seizures; Valproic Acid | 1999 |
Characterization of seizures in the flathead rat: a new genetic model of epilepsy in early postnatal development.
Topics: Animals; Anticonvulsants; Behavior, Animal; Brain; Cerebral Cortex; Disease Models, Animal; Electroencephalography; Epilepsy; Ethosuximide; Female; Male; Models, Genetic; Mutation; Phenobarbital; Rats; Rats, Mutant Strains; Rats, Wistar; Seizures; Valproic Acid | 1999 |
Valproate-induced biochemical abnormalities in pregnancy corrected by vitamins: a case report.
Topics: Adult; Anticonvulsants; Epilepsy; Ethosuximide; Female; Humans; Metabolic Diseases; Pantothenic Acid; Pregnancy; Pregnancy Complications; Valproic Acid; Vitamins | 1999 |
Hypersensitivity syndrome due to 2 anticonvulsant drugs.
Topics: Antibodies, Viral; Anticonvulsants; Child; Drug Hypersensitivity; Ethosuximide; Herpesvirus 6, Human; Humans; Male; Patch Tests; Syndrome; Valproic Acid | 1999 |
Epileptiform activity of veratridine model in rat brain slices: effects of antiepileptic drugs.
Topics: Action Potentials; Animals; Anticonvulsants; Convulsants; Ethosuximide; Hippocampus; Ion Channel Gating; Ion Transport; Phenytoin; Pyramidal Cells; Rats; Sodium; Sodium Channels; Valproic Acid; Veratridine | 2000 |
Sleep and epilepsy: A key role for nitric oxide?
Topics: Animals; Anticonvulsants; Brain; Cerebral Cortex; Circadian Rhythm; Disease Models, Animal; Electroencephalography; Enzyme Inhibitors; Epilepsy; Epilepsy, Absence; Ethosuximide; Humans; Male; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Rats; Rats, Wistar; Sleep; Valproic Acid; Wakefulness | 2000 |
Comparative profiles of sodium valproate and ethosuximide on electro-behavioural correlates in gamma-hydroxybutyrate and pentylenetetrazol induced absence seizures in rats.
Topics: Animals; Anticonvulsants; Convulsants; Disease Models, Animal; Electroencephalography; Epilepsy, Absence; Ethosuximide; Male; Pentylenetetrazole; Rats; Rats, Wistar; Sodium Oxybate; Species Specificity; Valproic Acid | 2000 |
Latent coeliac disease in a child with epilepsy, cerebral calcifications, drug-induced systemic lupus erythematosus and intestinal folic acid malabsorption associated with impairment of folic acid transport across the blood-brain barrier.
Topics: Adolescent; Anticonvulsants; Biological Transport; Blood-Brain Barrier; Brain; Brain Diseases; Calcinosis; Celiac Disease; Epilepsy; Ethosuximide; Folic Acid; Humans; Lupus Erythematosus, Systemic; Male; Urea; Valproic Acid | 2001 |
Interaction of flunarizine with sodium valproate or ethosuximide in gamahydroxybutyrate induced absence seizures in rats.
Topics: Animals; Anticonvulsants; Calcium Channel Blockers; Disease Models, Animal; Drug Interactions; Drug Synergism; Electroencephalography; Epilepsy, Absence; Ethosuximide; Flunarizine; Male; Rats; Rats, Wistar; Sodium Oxybate; Valproic Acid | 2001 |
Effects of antiepileptic drugs on induced epileptiform activity in a rat model of dysplasia.
Topics: 4-Aminopyridine; Action Potentials; Animals; Animals, Newborn; Anticonvulsants; Carbamazepine; Disease Models, Animal; Electroencephalography; Epilepsy; Ethosuximide; Female; Hippocampus; In Vitro Techniques; Lamotrigine; Methylazoxymethanol Acetate; Phenobarbital; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Triazines; Valproic Acid | 2002 |
Conventional anticonvulsant drugs in the guinea pig kindling model of partial seizures: effects of acute phenobarbital, valproate, and ethosuximide.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Epilepsies, Partial; Ethosuximide; Female; Forecasting; Guinea Pigs; Kindling, Neurologic; Male; Phenobarbital; Valproic Acid | 2002 |
Neuroprotective effects of anticonvulsants in rat hippocampal slice cultures exposed to oxygen/glucose deprivation.
Topics: Acetates; Amines; Animals; Anticonvulsants; Carbamates; Carbamazepine; Cell Death; Cells, Cultured; Chlordiazepoxide; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Ethosuximide; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Glucose; Hippocampus; Hypoxia; Ischemia; Lamotrigine; Levetiracetam; Midazolam; Neurons; Neuroprotective Agents; Nipecotic Acids; Oxcarbazepine; Phenobarbital; Phenylcarbamates; Phenylenediamines; Phenytoin; Piracetam; Propylene Glycols; Rats; Rats, Wistar; Tiagabine; Triazines; Valproic Acid | 2003 |
Speech and language deterioration in benign rolandic epilepsy.
Topics: Anomia; Anticonvulsants; Carbamazepine; Cerebral Cortex; Child; Child, Preschool; Cognition Disorders; Dose-Response Relationship, Drug; Drug Therapy, Combination; Dysarthria; Electroencephalography; Epilepsy, Rolandic; Ethosuximide; Evoked Potentials; Follow-Up Studies; Humans; Language Development Disorders; Male; Neuropsychological Tests; Prednisone; Speech Perception; Treatment Outcome; Valproic Acid; Verbal Learning | 2004 |
[Anticonvulsant hypersensitivity syndrome].
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Eruptions; Drug Hypersensitivity; Ethosuximide; Fever; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Lymphatic Diseases; Phenobarbital; Phenytoin; Syndrome; Triazines; Valproic Acid | 2004 |
[Long-term follow-up of a case of eyelid myoclonia with absences].
Topics: Adolescent; Clonazepam; Drug Therapy, Combination; Electroencephalography; Ethosuximide; Female; Follow-Up Studies; Humans; Myoclonus; Patient Compliance; Photophobia; Time Factors; Valproic Acid | 2004 |
Isobolographic and subthreshold analysis of interactions among felbamate and four conventional antiepileptic drugs in pentylenetetrazole-induced seizures in mice.
Topics: Animals; Anticonvulsants; Behavior, Animal; Clonazepam; Disease Models, Animal; Drug Interactions; Drug Synergism; Drug Therapy, Combination; Epilepsies, Myoclonic; Ethosuximide; Felbamate; Female; Humans; Lethal Dose 50; Mice; Motor Activity; Neurotoxicity Syndromes; Pentylenetetrazole; Phenobarbital; Phenylcarbamates; Propylene Glycols; Seizures; Valproic Acid | 2004 |
Ethosuximide and valproate display high efficacy against lindane-induced seizures in mice.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Ethosuximide; GABA Agents; Hexachlorocyclohexane; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Mice; Pentylenetetrazole; Seizures; Valproic Acid | 2004 |
Motor impairment on awakening in a patient with an EEG pattern of "unilateral, continuous spikes and waves during slow sleep".
Topics: Anticonvulsants; Arm; Benzodiazepines; Child; Clobazam; Electroencephalography; Epilepsy; Ethosuximide; Female; Humans; Movement; Psychomotor Disorders; Sleep; Valproic Acid | 2005 |
[Rickets. A rare complication of anti-epileptic treatments. Report of two cases in children].
Topics: Anticonvulsants; Black People; Calcifediol; Child; Contraindications; Drug Monitoring; Electroencephalography; Epilepsies, Myoclonic; Ergocalciferols; Ethosuximide; Humans; Male; Phenobarbital; Phenytoin; Radiography; Rare Diseases; Rickets; Valproic Acid | 1976 |
Pharmacodynamic and/or pharmacokinetic characteristics of interactions between loreclezole and four conventional antiepileptic drugs in pentylenetetrazole-induced seizures in mice: an isobolographic analysis.
Topics: Animals; Anticonvulsants; Clonazepam; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Ethosuximide; Kindling, Neurologic; Linear Models; Male; Mice; Pentylenetetrazole; Phenobarbital; Seizures; Triazoles; Valproic Acid | 2005 |
Characterization of the anticonvulsant, behavioral and pharmacokinetic interaction profiles of stiripentol in combination with clonazepam, ethosuximide, phenobarbital, and valproate using isobolographic analysis.
Topics: Animals; Anticonvulsants; Brain Chemistry; Clonazepam; Dioxolanes; Disease Models, Animal; Drug Interactions; Drug Therapy, Combination; Ethosuximide; Male; Mice; Neurotoxicity Syndromes; Pentylenetetrazole; Phenobarbital; Seizures; Valproic Acid | 2006 |
Conventional anticonvulsant drugs in the guinea-pig kindling model of partial seizures: effects of repeated administration.
Topics: Action Potentials; Amygdala; Animals; Anticonvulsants; Brain; Carbamazepine; Disease Models, Animal; Drug Administration Schedule; Drug Evaluation, Preclinical; Electric Stimulation; Epilepsies, Partial; Ethosuximide; Female; Guinea Pigs; Kindling, Neurologic; Male; Phenobarbital; Phenytoin; Predictive Value of Tests; Reproducibility of Results; Species Specificity; Treatment Outcome; Valproic Acid | 2007 |
Thalidomide inhibits pentylenetetrazole-induced seizures.
Topics: Analysis of Variance; Animals; Anticonvulsants; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Ethosuximide; Male; Pentylenetetrazole; Rats; Rats, Wistar; Seizures; Severity of Illness Index; Valproic Acid | 2007 |
Juvenile myoclonic epilepsy: a benign disorder? Personality traits and psychiatric symptoms.
Topics: Adolescent; Adult; Anticonvulsants; Child; Ethosuximide; Female; Fructose; Humans; Lamotrigine; Levetiracetam; Male; Mental Disorders; Myoclonic Epilepsy, Juvenile; Personality; Personality Tests; Piracetam; Psychiatric Status Rating Scales; Surveys and Questionnaires; Topiramate; Triazines; Valproic Acid | 2007 |
Temporal lobe epilepsy is a disease of faulty neuronal resonators rather than oscillators, and all seizures are provoked, usually by stress.
Topics: Anticonvulsants; Epilepsy; Epilepsy, Temporal Lobe; Ethosuximide; Hippocampus; Humans; Models, Neurological; Models, Theoretical; Neurons; Oscillometry; Seizures; Stress, Physiological; Treatment Outcome; Valproic Acid | 2007 |
Levetiracetam attenuates spontaneous spike-and-wave discharges in DBA/2J mice.
Topics: Animals; Anticonvulsants; Electroencephalography; Epilepsy, Absence; Ethosuximide; Injections, Intraperitoneal; Levetiracetam; Male; Mice; Mice, Inbred DBA; Piracetam; Valproic Acid | 2007 |
Robust isocratic high performance liquid chromatographic method for simultaneous determination of seven antiepileptic drugs including lamotrigine, oxcarbazepine and zonisamide in serum after solid-phase extraction.
Topics: Analysis of Variance; Animals; Anticonvulsants; Carbamazepine; Cattle; Chromatography, High Pressure Liquid; Drug Monitoring; Ethosuximide; Humans; Isoxazoles; Lamotrigine; Oxcarbazepine; Phenobarbital; Phenytoin; Primidone; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Solid Phase Extraction; Solutions; Specimen Handling; Spectrophotometry, Ultraviolet; Temperature; Triazines; Valproic Acid; Zonisamide | 2007 |
Childhood absence epilepsy with clinically apparent genetic and acquired burdens: a diagnostic consideration.
Topics: Action Potentials; Anticonvulsants; Birth Injuries; Brain; Causality; Child; Child, Preschool; Comorbidity; Cost of Illness; Diagnosis, Differential; Electroencephalography; Epilepsy, Absence; Ethosuximide; Female; Genetic Predisposition to Disease; Humans; Intellectual Disability; Male; Valproic Acid | 2008 |
Characterization of non-linear relationship between total and unbound serum concentrations of valproic acid in epileptic children.
Topics: Adolescent; Anticonvulsants; Binding Sites; Child; Child, Preschool; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Epilepsy; Ethosuximide; Humans; Infant; Nonlinear Dynamics; Protein Binding; Regression Analysis; Retrospective Studies; Valproic Acid | 2008 |
Valproic acid extends Caenorhabditis elegans lifespan.
Topics: Animals; Caenorhabditis elegans; Dose-Response Relationship, Drug; Ethosuximide; Longevity; Models, Animal; Time Factors; Trimethadione; Valproic Acid | 2008 |
Infantile spasms and Down syndrome: a new animal model.
Topics: 4-Butyrolactone; Animals; Anticonvulsants; Baclofen; Brain; Disease Models, Animal; Down Syndrome; Electroencephalography; Ethosuximide; GABA Agonists; Genotype; Humans; Infant; Mice; Mice, Mutant Strains; Organophosphorus Compounds; Phenotype; Receptors, GABA-A; Receptors, GABA-B; Spasms, Infantile; Time Factors; Valproic Acid; Vigabatrin | 2009 |
Isobolographic characterization of the anticonvulsant interaction profiles of levetiracetam in combination with clonazepam, ethosuximide, phenobarbital and valproate in the mouse pentylenetetrazole-induced seizure model.
Topics: Animals; Anticonvulsants; Clonazepam; Convulsants; Disease Models, Animal; Drug Interactions; Drug Therapy, Combination; Ethosuximide; Levetiracetam; Male; Mice; Pentylenetetrazole; Phenobarbital; Piracetam; Seizures; Valproic Acid | 2009 |
Rational treatment options with AEDs and ketogenic diet in Landau-Kleffner syndrome: still waiting after all these years.
Topics: Anticonvulsants; Behavior Therapy; Benzodiazepines; Child; Combined Modality Therapy; Diet, Ketogenic; Electroencephalography; Epilepsies, Partial; Ethosuximide; Humans; Immunoglobulins, Intravenous; Landau-Kleffner Syndrome; Sleep; Speech Therapy; Status Epilepticus; Valproic Acid | 2009 |
Use of a new antiepileptic drug or an old one as first drug for treatment of absence epilepsy.
Topics: Anticonvulsants; Drug Monitoring; Epilepsy, Absence; Ethosuximide; Humans; Lamotrigine; Treatment Outcome; Triazines; Valproic Acid | 2009 |
Ethosuximide in childhood absence epilepsy--older and better.
Topics: Anticonvulsants; Child; Diagnosis, Differential; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Ethosuximide; Humans; Lamotrigine; Triazines; Valproic Acid | 2010 |
When the past challenges the present: are older antiepileptic drugs still the best choice in childhood absence epilepsy?
Topics: Anticonvulsants; Child; Epilepsy, Absence; Ethosuximide; Humans; Randomized Controlled Trials as Topic; Valproic Acid | 2010 |
Gastaut type-idiopathic childhood occipital epilepsy and childhood absence epilepsy: a clinically significant association?
Topics: Anticonvulsants; Blindness; Child; Electroencephalography; Epilepsy; Epilepsy, Absence; Ethosuximide; Hallucinations; Humans; Male; Migraine Disorders; Occipital Lobe; Unconsciousness; Valproic Acid | 2010 |
Long-term outcome of 32 children with encephalopathy with status epilepticus during sleep, or ESES syndrome.
Topics: Adolescent; Anticonvulsants; Child; Cognition Disorders; Drug Therapy, Combination; Electroencephalography; Epilepsy, Rolandic; Ethosuximide; Female; Humans; Landau-Kleffner Syndrome; Longitudinal Studies; Male; Prospective Studies; Seizures; Sleep Wake Disorders; Status Epilepticus; Syndrome; Treatment Outcome; Valproic Acid | 2010 |
An older drug for childhood absence epilepsy.
Topics: Anticonvulsants; Child; Electroencephalography; Epilepsy, Absence; Ethosuximide; Humans; Lamotrigine; Randomized Controlled Trials as Topic; Treatment Outcome; Triazines; Valproic Acid | 2010 |
Long term outcome in children affected by absence epilepsy with onset before the age of three years.
Topics: Adolescent; Age of Onset; Anticonvulsants; Child; Child, Preschool; Cognition; Epilepsy, Absence; Ethosuximide; Female; Humans; Italy; Longitudinal Studies; Male; Neuropsychological Tests; Retrospective Studies; Treatment Outcome; Valproic Acid | 2011 |
Effects of WIN 55,212-2 mesylate (a synthetic cannabinoid) on the protective action of clonazepam, ethosuximide, phenobarbital and valproate against pentylenetetrazole-induced clonic seizures in mice.
Topics: Animals; Anticonvulsants; Avoidance Learning; Benzoxazines; Brain; Cannabinoid Receptor Agonists; Clonazepam; Disease Models, Animal; Drug Synergism; Ethosuximide; Hand Strength; Male; Mice; Morpholines; Naphthalenes; Pentylenetetrazole; Phenobarbital; Seizures; Valproic Acid | 2011 |
Long-term effectiveness of ethosuximide, valproic acid, and lamotrigine in childhood absence epilepsy.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Electroencephalography; Epilepsy, Absence; Ethosuximide; Female; Follow-Up Studies; Humans; Lamotrigine; Male; Retrospective Studies; Treatment Outcome; Triazines; Valproic Acid; Young Adult | 2012 |
[Transitory cognitive dysfunction in rolandic epilepsy].
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Cognition Disorders; Drug Therapy, Combination; Epilepsy, Rolandic; Ethosuximide; Female; Humans; Levetiracetam; Male; Piracetam; Recovery of Function; Remission Induction; Valproic Acid | 2011 |
[Idiopathic focal epilepsies of infancy and childhood].
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Drug Resistance; Drug Therapy, Combination; Electroencephalography; Epilepsies, Partial; Epilepsy, Rolandic; Ethosuximide; Female; Humans; Infant; Levetiracetam; Male; Piracetam; Valproic Acid | 2011 |
Epileptiform activity and cognitive deficits in SNAP-25(+/-) mice are normalized by antiepileptic drugs.
Topics: Animals; Anticonvulsants; Association Learning; Brain; Carbamazepine; Cognition Disorders; Epilepsy; Ethosuximide; Hyperkinesis; Kainic Acid; Male; Memory Disorders; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurons; Nimodipine; Seizures; Synaptosomal-Associated Protein 25; Valproic Acid | 2014 |
[Epilepsies with electric status epilepticus in sleep: peculiarities of clinical course and rational approaches to treatment].
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Resistance; Electricity; Electroencephalography; Ethosuximide; Female; Humans; Levetiracetam; Male; Piracetam; Sleep Stages; Sleep Wake Disorders; Status Epilepticus; Syndrome; Valproic Acid | 2011 |
How did phenobarbital's chemical structure affect the development of subsequent antiepileptic drugs (AEDs)?
Topics: Anticonvulsants; Carbamazepine; Drug Discovery; Epilepsy; Ethosuximide; History, 20th Century; Humans; Mephenytoin; Mephobarbital; Phenobarbital; Phenytoin; Primidone; Structure-Activity Relationship; Succinimides; Valproic Acid | 2012 |
Assessment of control in typical childhood absence epilepsy.
Topics: Anticonvulsants; Child; Data Collection; Electroencephalography; Epilepsy, Absence; Ethosuximide; Follow-Up Studies; Humans; Neurology; Practice Patterns, Physicians'; Surveys and Questionnaires; Valproic Acid | 2013 |
Teratogenic potential of antiepileptic drugs in the zebrafish model.
Topics: Acetamides; Animals; Anticonvulsants; Carbamazepine; Disease Models, Animal; Ethosuximide; Female; Fructose; Humans; Lacosamide; Lamotrigine; Levetiracetam; Piracetam; Pregnancy; Teratogenesis; Topiramate; Triazines; United States; Valproic Acid; Zebrafish | 2013 |
Zebrafish embryotoxicity test for developmental (neuro)toxicity: Demo case of an integrated screening approach system using anti-epileptic drugs.
Topics: Animals; Anticonvulsants; Brain; Carbamazepine; Dose-Response Relationship, Drug; Endpoint Determination; Ethosuximide; In Situ Hybridization; Levetiracetam; Piracetam; Toxicity Tests; Valproic Acid; Zebrafish | 2014 |
Synthesis, physicochemical, and anticonvulsant properties of new N-Mannich bases derived from pyrrolidine-2,5-dione and its 3-methyl analog.
Topics: Animals; Anticonvulsants; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Design; Electroshock; Ethosuximide; Male; Mannich Bases; Mice; Molecular Structure; Motor Activity; Neurotoxicity Syndromes; Pentylenetetrazole; Pyrrolidines; Rotarod Performance Test; Seizures; Structure-Activity Relationship; Valproic Acid | 2014 |
Interactions between an antidepressant reboxetine and four classic antiepileptic drugs in the mouse model of myoclonic seizures.
Topics: Animals; Anticonvulsants; Antidepressive Agents; Avoidance Learning; Clonazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Epilepsies, Myoclonic; Ethosuximide; Male; Mice; Morpholines; Motor Skills; Pentylenetetrazole; Phenobarbital; Reboxetine; Valproic Acid | 2015 |
Long-term prognosis of childhood absence epilepsy.
Topics: Adolescent; Anticonvulsants; Child; Disease Progression; Epilepsy, Absence; Ethosuximide; Female; Humans; Male; Prognosis; Retrospective Studies; Treatment Outcome; Valproic Acid | 2019 |
Bilateral subacute lacrimal gland enlargement mimicking dacryoadenitis in a 7-year-old boy: a rare adverse effect of valproic acid (sodium valproate).
Topics: Acute Disease; Anticonvulsants; Child; Dacryocystitis; Diagnosis, Differential; Drug Substitution; Ethosuximide; Humans; Lacrimal Apparatus Diseases; Male; Submandibular Gland Diseases; Valproic Acid | 2017 |
Inattention and Poor Eye Contact Is Not All Autism.
Topics: Anticonvulsants; Autism Spectrum Disorder; Child; Diagnosis, Differential; Electroencephalography; Epilepsy; Ethosuximide; Humans; Male; Valproic Acid | 2017 |
The effects of ethosuximide on aversive instrumental learning in adult rats.
Topics: Animals; Anticonvulsants; Appetite; Avoidance Learning; Cognition; Conditioning, Operant; Ethosuximide; Learning; Rats; Rats, Sprague-Dawley; Valproic Acid | 2018 |
Long-term negative impact of an inappropriate first antiepileptic medication on the efficacy of a second antiepileptic medication in mice.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Drug Therapy, Combination; Electroencephalography; Epilepsy, Absence; Ethosuximide; Inappropriate Prescribing; Male; Mice; Mice, Inbred Strains; Saline Solution; Treatment Outcome; Valproic Acid; Vigabatrin | 2018 |
Pharmacological characterization of nicotine-induced tremor: Responses to anti-tremor and anti-epileptic agents.
Topics: Animals; Anticonvulsants; Antiparkinson Agents; Benzeneacetamides; Calcium Channel Blockers; Carbamazepine; Diazepam; Disease Models, Animal; Essential Tremor; Ethosuximide; Male; Mice, Inbred Strains; Nicotine; Phenobarbital; Propranolol; Pyridines; Valproic Acid | 2018 |
Early clinical and EEG findings associated with the outcome in childhood absence epilepsy.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Electroencephalography; Epilepsy, Absence; Ethosuximide; Female; Follow-Up Studies; Humans; Male; Recurrence; Treatment Outcome; Valproic Acid | 2019 |
N-Benzyl-(2,5-dioxopyrrolidin-1-yl)propanamide (AS-1) with Hybrid Structure as a Candidate for a Broad-Spectrum Antiepileptic Drug.
Topics: Animals; Anticonvulsants; Behavior, Animal; Dose-Response Relationship, Drug; Epilepsy; Ethosuximide; Lacosamide; Levetiracetam; Male; Mice; Pentylenetetrazole; Pyrrolidines; Seizures; Valproic Acid; Zebrafish | 2020 |
De novo Absence Status Epilepticus in a pediatric cohort: Electroclinical pattern in a multicenter Italian patients cohort.
Topics: Adolescent; Anticonvulsants; Child; Electroencephalography; Epilepsy; Ethosuximide; Female; Humans; Italy; Male; Retrospective Studies; Status Epilepticus; Valproic Acid; Young Adult | 2019 |
Long-term vigabatrin treatment modifies pentylenetetrazole-induced seizures in mice: focused on GABA brain concentration.
Topics: 4-Aminobutyrate Transaminase; Animals; Anticonvulsants; Brain; Clonazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Ethosuximide; gamma-Aminobutyric Acid; Mice; Pentylenetetrazole; Seizures; Time Factors; Valproic Acid; Vigabatrin | 2020 |
Contribution of rare genetic variants to drug response in absence epilepsy.
Topics: Anticonvulsants; Epilepsy, Absence; Ethosuximide; gamma-Aminobutyric Acid; Humans; Pharmaceutical Preparations; Valproic Acid | 2021 |
Effects of antiseizure monotherapy on visuospatial memory in pediatric age.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Epilepsy; Ethosuximide; Executive Function; Female; Humans; Levetiracetam; Longitudinal Studies; Male; Neuropsychological Tests; Retrospective Studies; Spatial Memory; Valproic Acid | 2021 |
Pharmacotherapeutic management of seizures in patients with Angleman Syndrome.
Topics: Anticonvulsants; Cannabidiol; Child; Clobazam; Clonazepam; Ethosuximide; Humans; Lamotrigine; Levetiracetam; Quality of Life; Seizures; Topiramate; Valproic Acid | 2022 |
[Epilepsy in Angelman syndrome].
Topics: Angelman Syndrome; Anticonvulsants; Child; Electroencephalography; Epilepsy; Ethosuximide; Female; Humans; Levetiracetam; Male; Seizures; Valproic Acid | 2022 |