valproic acid has been researched along with ethinyl estradiol in 24 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (8.33) | 18.7374 |
| 1990's | 1 (4.17) | 18.2507 |
| 2000's | 13 (54.17) | 29.6817 |
| 2010's | 8 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Strassburg, CP; Tukey, RH | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Chang, TK; Ensom, MH; Kiang, TK | 1 |
| Jolivette, LJ; Ward, KW | 1 |
| Dansette, PM; Fontana, E; Poli, SM | 1 |
| Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Glen, RC; Lowe, R; Mitchell, JB | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Honda, K; Izumi, T; Miyaji, Y; Nakayama, S; Okazaki, O; Okudaira, N; Shiosakai, K; Sugiyama, D; Suzuki, W; Takakusa, H; Watanabe, A | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Banay-Schwartz, M; De Guzman, T; Lajtha, A; Zanchin, G | 1 |
| Back, DJ; Chadwick, D; Cleland, P; Cowie, A; Crawford, P; Orme, ML; Tjia, J | 1 |
| Doose, DR; Nayak, RK; Rosenfeld, WE; Walker, SA | 1 |
| Blum, AS; Farina, EL; Herzog, AG | 1 |
| Arbasino, C; Canevini, MP; Fattore, C; Galimberti, CA; Mazzucchelli, I; Perucca, E | 1 |
| Reimers, A; Skogvoll, E; Spigset, O; Sund, JK | 1 |
| Endo, T; Kawamura, S; Maruta, M; Sakai, A | 1 |
| Bouker, KB; Clarke, R; Cook, KL; Cruz, MI; de Assis, S; Hilakivi-Clarke, L; Hu, R; Jin, L; Nguyen, N; Wang, X; Wang, Y; Wärri, A; Wehrenberg, B; Xuan, J; Zhang, X; Zwart, A | 1 |
3 review(s) available for valproic acid and ethinyl estradiol
| Article | Year |
|---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic | 2000 |
UDP-glucuronosyltransferases and clinical drug-drug interactions.
Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic | 2005 |
Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity.
Topics: Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Humans; Isoenzymes; Structure-Activity Relationship; Terminology as Topic | 2005 |
21 other study(ies) available for valproic acid and ethinyl estradiol
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.
Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution | 2005 |
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Combination of GSH trapping and time-dependent inhibition assays as a predictive method of drugs generating highly reactive metabolites.
Topics: Glutathione; Pharmacology; Sulfur Radioisotopes | 2011 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
The effect of corticosteroids on amino acid content of brain tissue preparations.
Topics: Adrenal Cortex Hormones; Amino Acids; Animals; Brain; Culture Techniques; Dexamethasone; Estradiol; Ethinyl Estradiol; gamma-Aminobutyric Acid; Hydrocortisone; Mice; Progesterone; Valproic Acid | 1979 |
The lack of effect of sodium valproate on the pharmacokinetics of oral contraceptive steroids.
Topics: Adolescent; Adult; Contraceptives, Oral; Drug Interactions; Ethinyl Estradiol; Female; Humans; Kinetics; Levonorgestrel; Norgestrel; Valproic Acid | 1986 |
Effect of topiramate on the pharmacokinetics of an oral contraceptive containing norethindrone and ethinyl estradiol in patients with epilepsy.
Topics: Adult; Anticonvulsants; Contraception; Contraceptives, Oral, Combined; Contraceptives, Oral, Synthetic; Epilepsy; Estradiol Congeners; Ethinyl Estradiol; Female; Fructose; Humans; Norethindrone; Progesterone; Topiramate; Valproic Acid | 1997 |
Serum valproate levels with oral contraceptive use.
Topics: Adult; Anticonvulsants; Comorbidity; Contraceptives, Oral, Combined; Drug Combinations; Drug Interactions; Epilepsy; Ethinyl Estradiol; Ethynodiol Diacetate; Female; Humans; Menorrhagia; Menstruation Disturbances; Valproic Acid | 2005 |
Increased apparent oral clearance of valproic acid during intake of combined contraceptive steroids in women with epilepsy.
Topics: Administration, Oral; Adolescent; Adult; Anticonvulsants; Contraceptives, Oral, Combined; Contraceptives, Oral, Hormonal; Drug Interactions; Drug Monitoring; Enzyme Induction; Epilepsy; Ethinyl Estradiol; Female; Fluorescence Polarization Immunoassay; Glucuronosyltransferase; Humans; Valproic Acid | 2006 |
Lamotrigine in children and adolescents: the impact of age on its serum concentrations and on the extent of drug interactions.
Topics: Adolescent; Adult; Age Factors; Anticonvulsants; Antidepressive Agents; Benzodiazepines; Child; Child, Preschool; Contraceptives, Oral, Combined; Drug Interactions; Drug Therapy, Combination; Ethinyl Estradiol; Female; Fluoxetine; Humans; Lamotrigine; Male; Models, Biological; Triazines; Valproic Acid | 2007 |
Atypical depression as a premonitory symptom of migraine managed by an oral contraceptive.
Topics: Adult; Alprazolam; Borderline Personality Disorder; Calcium Channel Blockers; Contraceptives, Oral, Combined; Depressive Disorder, Major; Drug Combinations; Drug Therapy, Combination; Female; Humans; Mestranol; Migraine with Aura; Norethindrone; Piperazines; Suicide, Attempted; Valproic Acid | 2008 |
Effects of In Utero Exposure to Ethinyl Estradiol on Tamoxifen Resistance and Breast Cancer Recurrence in a Preclinical Model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenovirus E1A Proteins; Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Line, Tumor; DNA Methylation; Drug Resistance, Neoplasm; Ethinyl Estradiol; Female; Galectin 3; Gene Expression; Gene Silencing; Histocompatibility Antigens Class I; Humans; Hydralazine; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Mammary Neoplasms, Experimental; Neoplasm Recurrence, Local; Pregnancy; Prenatal Exposure Delayed Effects; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ets; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Tamoxifen; Trans-Activators; Valproic Acid | 2017 |