valproic acid and digoxin

valproic acid has been researched along with digoxin in 30 studies

Research

Studies (30)

Timeframe	Studies, this research(%)	All Research%
pre-1990	3 (10.00)	18.7374
1990's	4 (13.33)	18.2507
2000's	10 (33.33)	29.6817
2010's	11 (36.67)	24.3611
2020's	2 (6.67)	2.80

Authors

Authors	Studies
Abraham, MH; Acree, WE; Ibrahim, A	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
Lombardo, F; Obach, RS; Waters, NJ	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y	1
Ahlers, AA; Nielsen, C	1
Gal, J; Molitoris, BA; Nakata, LM; Sedman, AJ	1
Buchanan, N	1
Müller, FO; Steyn, JM	1
Chyka, PA; Holley, JE; Mandrell, TD; Sugathan, P	1
Cai, S; Castela-Papin, N; Farinotti, R; Keller, F; Souleau, CH; Vatier, J	1
Soldin, SJ	1
Bellomo, R; Bordoni, V; D'Intini, V; Dall'Olio, G; Galloni, E; Reiter, K; Ricatti, MG; Ronco, C; Ruperti, S; Soffiati, G; Soli, M	1
Al-Beshri, M; AL-Ghamdi, HA; EL Desoky, ES; Halaby, FH	1
Dalaklioglu, S	1
Mishchenko, M; Shtrygol, D; Shtrygol, S; Tsyvunin, V	1
Gorbach, T; Lytkin, D; Mishchenko, M; Shtrygol, D; Shtrygol, S; Taran, A; Tsyvunin, V	1

Reviews

2 review(s) available for valproic acid and digoxin

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Therapeutic drug monitoring in childhood. Australian paediatric journal, 1986, Volume: 22, Issue:1 Topics: Aminoglycosides; Anti-Bacterial Agents; Carbamazepine; Child; Chloramphenicol; Digoxin; Drug Interactions; Half-Life; Humans; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Saliva; Theophylline; Valproic Acid	1986

Other Studies

28 other study(ies) available for valproic acid and digoxin

Article	Year
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs. European journal of medicinal chemistry, 2008, Volume: 43, Issue:3 Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization	2008
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships. Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16 Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone	2016
[Therapeutic monitoring of drug concentration in blood. Are the analyses correctly ordered?]. Ugeskrift for laeger, 1991, Apr-29, Volume: 153, Issue:18 Topics: Blood Chemical Analysis; Carbamazepine; Digoxin; Drug Administration Schedule; Humans; Lithium; Monitoring, Physiologic; Surveys and Questionnaires; Theophylline; Valproic Acid	1991
Therapeutic drug monitoring in patients with chronic renal failure: evaluation of the Abbott TDx drug assay system. American journal of nephrology, 1986, Volume: 6, Issue:2 Topics: Carbamazepine; Cross Reactions; Digoxin; Gentamicins; Humans; Immunoassay; Kidney Failure, Chronic; Lidocaine; Monitoring, Physiologic; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Quinidine; Valproic Acid; Vancomycin	1986
Comparative effects of two commercially available blood collection tubes on plasma concentrations of drugs. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1980, Jan-26, Volume: 57, Issue:4 Topics: Acebutolol; Blood Specimen Collection; Carbamazepine; Diazepam; Digoxin; Ethosuximide; Humans; Nordazepam; Penbutolol; Pharmaceutical Preparations; Propranolol; Quinidine; Salicylates; Time Factors; Valproic Acid; Warfarin	1980
Correlation of drug pharmacokinetics and effectiveness of multiple-dose activated charcoal therapy. Annals of emergency medicine, 1995, Volume: 25, Issue:3 Topics: Acetaminophen; Animals; Charcoal; Digoxin; Disease Models, Animal; Drug Administration Schedule; Female; Half-Life; Linear Models; Metabolic Clearance Rate; Pharmacokinetics; Poisoning; Poisons; Prospective Studies; Random Allocation; Swine; Theophylline; Valproic Acid	1995
Drug interactions with diosmectite: a study using the artificial stomach-duodenum model. International journal of pharmaceutics, 1999, May-10, Volume: 182, Issue:1 Topics: Adsorption; Animals; Anti-Infective Agents; Cimetidine; Dapsone; Digoxin; Drug Interactions; Duodenum; Fluoroquinolones; Gastric Mucosa; Gastrointestinal Agents; Hydrogen-Ion Concentration; Intestinal Absorption; Metronidazole; Models, Biological; Pharmacokinetics; Silicates; Stomach; Swine; Valproic Acid	1999
Free drug measurements. When and why? An overview. Archives of pathology & laboratory medicine, 1999, Volume: 123, Issue:9 Topics: Biological Availability; Carbamazepine; Digoxin; Pharmaceutical Preparations; Pharmacokinetics; Phenytoin; Protein Binding; Temperature; Valproic Acid	1999
In vitro removal of therapeutic drugs with a novel adsorbent system. Blood purification, 2002, Volume: 20, Issue:4 Topics: Adsorption; Anti-Bacterial Agents; Biocompatible Materials; Carbamazepine; Digoxin; Glycopeptides; Hemoperfusion; Humans; Models, Biological; Phenobarbital; Phenytoin; Sorption Detoxification; Theophylline; Uremia; Valproic Acid	2002
Therapeutic monitoring of digoxin and antiepileptic drugs in Egypt and Saudi Arabia. Therapeutic drug monitoring, 2003, Volume: 25, Issue:2 Topics: Anticonvulsants; Carbamazepine; Cardiotonic Agents; Developing Countries; Digoxin; Drug Monitoring; Egypt; Humans; Phenytoin; Retrospective Studies; Saudi Arabia; Valproic Acid	2003
Evaluating appropriateness of digoxin, carbamazepine, valproic acid, and phenytoin usage by therapeutic drug monitoring. Clinical laboratory, 2013, Volume: 59, Issue:3-4 Topics: Animals; Carbamazepine; Digoxin; Humans; Monitoring, Physiologic; Phenytoin; Valproic Acid	2013
Digoxin at sub-cardiotonic dose modulates the anticonvulsive potential of valproate, levetiracetam and topiramate in experimental primary generalized seizures. Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti, 2022,Spring, Volume: 71, Issue:2 Topics: Animals; Anticonvulsants; Camphor; Cardiotonic Agents; Digoxin; Levetiracetam; Male; Mice; Picrotoxin; Seizures; Strychnine; Topiramate; Valproic Acid	2022
Effect of digoxin, sodium valproate, and celecoxib on the cerebral cyclooxygenase pathway and neuron-specific enolase under the pentylenetetrazole-induced kindling in mice. Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti, 2023,Fall, Volume: 72, Issue:4 Topics: Animals; Anticonvulsants; Celecoxib; Digoxin; Epilepsy; Mice; Neuroinflammatory Diseases; Pentylenetetrazole; Phosphopyruvate Hydratase; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Valproic Acid	2023