valproic acid has been researched along with diazepam in 231 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 100 (43.29) | 18.7374 |
| 1990's | 48 (20.78) | 18.2507 |
| 2000's | 46 (19.91) | 29.6817 |
| 2010's | 30 (12.99) | 24.3611 |
| 2020's | 7 (3.03) | 2.80 |
| Authors | Studies |
|---|---|
| Johnson, DN; Kilpatrick, BF; Kinnier, WB; Lo, YS; Moses, LM; Sutherland, DB; Taylor, CR; Tomczuk, BE | 1 |
| Baron, BM; Dudley, MW; Kane, JM; Miller, FP; Sorensen, SM; Staeger, MA | 1 |
| Andrews, PR; Craik, DJ; Martin, JL | 1 |
| Dalton, CR; Dudley, MW; Kane, JM; Kehne, JH; Ketteler, HJ; McCloskey, TC; Miller, FP; Ogden, AM; Senyah, Y; Staeger, MA | 1 |
| Bonsignori, A; Colombo, M; Dostert, P; Fariello, RG; Heidempergher, F; McArthur, RA; Pevarello, P; Pinciroli, V; Post, C; Salvati, P; Varasi, M | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Chang, TK; Ensom, MH; Kiang, TK | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Abraham, MH; Acree, WE; Ibrahim, A | 1 |
| Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Glen, RC; Lowe, R; Mitchell, JB | 1 |
| Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC | 1 |
| Atzpodien, EA; Csato, M; Doessegger, L; Fischer, H; Lenz, B; Schmitt, G; Singer, T | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Filipek, B; Gunia-Krzyżak, A; Marona, H; Nitek, W; Pańczyk, K; Pękala, E; Rapacz, A; Słoczyńska, K; Waszkielewicz, AM; Żelaszczyk, D; Żesławska, E | 1 |
| Akhtar, MJ; Bhatia, R; Grover, G; Nath, R | 1 |
| Bohlen, N; Hertl, M | 1 |
| Richens, A | 1 |
| Loiseau, P | 1 |
| Araki, Y; Ueki, S; Watanabe, S | 1 |
| Hori, M; Ito, T; Shimizu, M; Yoshida, K | 3 |
| Dahlström, S; Kangas, L; Koulu, M; Lammintausta, R | 1 |
| Reith, H; Schäfer, H | 1 |
| Curless, RG | 1 |
| Aicardi, J | 1 |
| Wada, JA | 1 |
| Molodavkin, GM; Ostrovskaia, RU | 1 |
| Gastaut, H; Osuntokun, BO | 1 |
| Dam, M; Hvidberg, EF | 1 |
| Coulthard, MG | 1 |
| Fukusako, T; Morimatsu, M; Nogaki, H; Yamamoto, K | 1 |
| Hönack, D; Löscher, W | 1 |
| Kim, CK; Mana, MJ; Pinel, JP | 1 |
| Jones, CH; Kim, CK; Mana, MJ; Pinel, JP | 1 |
| Fujita, T; Takano, K; Tanaka, S; Tanaka, T; Yonemasu, Y | 1 |
| David, J; Joseph, T; Kulkarni, C | 1 |
| Georgiev, VP; Kambourova, TS; Lazarova, MB | 1 |
| Biggio, G; Concas, A; Mascia, MP; Sanna, E; Santoro, G; Serra, M | 1 |
| Lloyd, KG; Naquet, R; Valin, A; Voltz, C | 1 |
| Corbett, R; Cornfeldt, M; Dunn, RW; Fielding, S | 1 |
| Bowmer, CJ; Panjehshahin, MR; Yates, MS | 1 |
| Breimer, DD; de Boer, AG; van Hoogdalem, E | 1 |
| Bagri, A; Di Scala, G; Sandner, G | 1 |
| Keck, PE; Lawrence, JM; McElroy, SL | 1 |
| Fredow, G; Löscher, W | 1 |
| Löscher, W; Wahnschaffe, U | 1 |
| Biggio, G; Concas, A; Mascia, MP; Sanna, E; Santoro, V; Serra, M | 1 |
| Hönack, D; Löscher, W; Wahnschaffe, U | 1 |
| Anai, T; Hirota, Y; Miyakawa, I; Oga, M; Yoshimatsu, J | 1 |
| Czuczwar, SJ; Janusz, W; Kleinrok, Z; Szczepanik, B; Wamil, A | 1 |
| Ankerhus, J; Brems, M; Daugbjerg, P; Knudsen, FU; Mai, J | 1 |
| McKinlay, I; Newton, R | 1 |
| Dvorák, A; Fácková, M; Husovská, G; Pavlícek, N; Tosnerová, T; Vinar, O; Vinarová, E | 1 |
| Czuczwar, SJ; Janusz, W; Kleinrok, Z; Wamil, A | 1 |
| Meldrum, BS | 1 |
| Bidziński, A; Hauptmann, M; Kostowski, W; Płaźnik, A; Tamborska, E | 1 |
| Bender, AS; Hertz, L | 1 |
| Kryzhanovskiĭ, GN; Shandra, AA | 1 |
| Samanin, R; Tullii, M; Vezzani, A; Wu, HQ | 1 |
| Green, AR; Johnson, P; Mountford, JA; Nimgaonkar, VL | 1 |
| Moura, D; Soares-da-Silva, P | 1 |
| Dewhurst, DG | 1 |
| Vellucci, SV; Webster, RA | 1 |
| Antinori, D; de Ruggiero, A; Fioretti, P; Mais, V; Melis, GB; Paoletti, AM | 1 |
| Bakalakis, S; Facchinetti, F; Genazzani, AR; Muller, EE; Petraglia, F; Volpe, A | 1 |
| Löscher, W | 1 |
| Endsley, B; Leibold, L; Picker, M; Poling, A | 1 |
| Calvo, R; Carlos, R; Erill, S | 1 |
| Hvorslev, V; Lee, K; Taudorf, K | 1 |
| Bentley, M; Feely, M; Gent, JP; Haigh, JR | 1 |
| Belknap, JK; Crabbe, JC; Kosobud, A; Laursen, SE; Tam, B; Young, ER | 1 |
| Biziere, K; Calassi, R; Chambon, JP; Heaulme, M; Perio, A | 1 |
| Freed, WJ; Schwarz, SS | 1 |
| Dulac, O; Jambaque, I; Motte, J; Plouin, P | 1 |
| Watanabe, K | 1 |
| Meyer, FP; Walther, H | 1 |
| Rosman, NP | 1 |
| Cabrero, A; Fernández, RM; Fidalgo, I; Mosquera, C; Rodríguez, J | 1 |
| Préaubert, G; Schnetzler, F; Schnetzler, JP | 1 |
| Lindhout, D; Reuss, A; Sachs, ES; Stewart, PA; van Swaay, E; Wladimiroff, JW | 1 |
| Depaulis, A; Marescaux, C; Micheletti, G; Reis, J; Rumbach, L; Vergnes, M; Warter, JM | 1 |
| García Ruiz, A; Gómez Luque, A; Martos Crespo, F; Sánchez de la Cuesta, F | 1 |
| Chweh, AY; Coleman, JC; Shenoy, AK; Swinyard, EA | 1 |
| Baltzer, V; Bernasconi, R; Jones, RS; Klein, M; Maître, L; Martin, P; Portet, C; Schmutz, M | 1 |
| Cano, JP; Hariton, C; Jadot, G; Mandel, P; Mesdjian, E | 1 |
| Kazandjian, A; Spyraki, C; Varonos, D | 1 |
| Frey, HH; Löscher, W | 1 |
| Jähkel, M; Oehler, J; Schmidt, J | 1 |
| Harada, S; Itoh, N; Mimaki, T; Suzuki, Y; Tagawa, T; Tanaka, J; Terada, H; Yabuuchi, H | 1 |
| Abbott, LC; Bennett, GD; Finnell, RH; Taylor, SM | 1 |
| Hanano, M; Iga, T; Sawada, Y; Sugiyama, Y | 1 |
| Bencze, W; Bernasconi, R; Hauser, K; Klein, M; Martin, P; Schmutz, M | 1 |
| Dunn, R; Fielding, S; Kruse, H; Lal, H; Shearman, GT; Theurer, K | 1 |
| Kharlamov, AN; Kozlovskaia, MM; Raevskiĭ, KS; Val'dman, AV | 1 |
| Abraham, RR; Beckford, U; Dornhorst, A; Gillham, B; Jones, MT; Seed, M; Wynn, V | 1 |
| Kosoĭ, MIu | 1 |
| Calderazzo, L; Cepeda, C; Naquet, R; Stutzmann, JM; Valin, A | 1 |
| Davis, WC; Ticku, MK | 1 |
| Morag, M; Myslobodsky, M | 1 |
| Gardner, CR; Piper, DC | 1 |
| Adamec, R; Racine, RJ; Tuff, LP | 1 |
| Petersen, EN | 1 |
| Friel, PN; Koch, KM; Levy, RH; Lockard, JS; Maris, DO | 1 |
| Kofman, O; Myslobodsky, MS | 1 |
| Bruni, J; Somerville, ER | 1 |
| Fukuda, H; Goto, M; Hasebe, Y; Kaneko, T; Kato, K | 1 |
| Hvidberg, EF | 1 |
| Escorihuela, R; Sandiumenge, J | 1 |
| Frey, HH; Löscher, W; Reiche, R; Schultz, D | 2 |
| Altmann, H; Dose, M; Emrich, HM; von Zerssen, D | 1 |
| Procopis, PG | 1 |
| Bleck, TP | 1 |
| Post, RM; Uhde, TW | 1 |
| Duwe, K; Kuhnz, W; Nau, H; Wittfoht, W | 1 |
| Battistin, L; Berlese, G; Roman, G; Varotto, M | 1 |
| Bourguignon, A; Cadet, B; Chaneac, D; de Medeiros, P; Monfort, JC | 1 |
| Dahlström, S; Koulu, M; Lammintausta, R | 1 |
| Franco-Morselli, R; Morselli, PL | 1 |
| Müller, FO; Steyn, JM | 1 |
| Fröscher, W | 1 |
| Addy, DP | 1 |
| Marumo, H; Ohmori, K; Shuto, K; Yamanami, S | 1 |
| Perucca, E; Richens, A; Ruprah, M | 1 |
| Czuczwar, SJ; Kleinrok, Z; Turski, L; Turski, W | 1 |
| Scollo-Lavizzari, G | 1 |
| Fuller, TA; Olney, JW | 1 |
| Dhillon, S; Richens, A | 2 |
| Bonardi, JM; Juif, J; Marescaux, C; Micheletti, G; Rumbach, L; Warter, JM | 1 |
| Clifford, DB; Dodson, WE; Ferrendelli, JA; Lothman, EW | 1 |
| Kupferberg, HJ; Miyahara, JT; Shenoy, AK; Swinyard, EA | 1 |
| Helwig, H; Staudt, F | 1 |
| Bourrillon, A | 1 |
| Becker, A; Grecksch, G; Ostner, C; Piönnigs, B | 1 |
| Abrosimov, IIu; Karpova, MN; Kryzhanovskiĭ, GN | 2 |
| Hekster, YA; Keyser, A; Lammers, MW; Meinardi, H; Renier, WO; van Lier, H; Wijsman, DJ | 1 |
| Camacho, F; Garcia-Bravo, B; Rodriguez-Pichardo, A | 1 |
| Amico-Roxas, M; Caruso, A; Cutuli, VM; de Bernardis, E; Lucenti, A; Villari, L | 1 |
| Chakrabarti, A; Chugh, Y; Sharma, PL | 1 |
| Hirohashi, M; Kitano, Y; Nomura, M; Takasuna, K; Usui, C | 1 |
| Aguglia, U; De Sarro, A; De Sarro, G; Nava, F | 1 |
| George, B; Kulkarni, SK | 1 |
| Balian, JD; Mahmood, I | 1 |
| Dalvi, A; Rodgers, RJ | 2 |
| Morton, LD; Pellock, JM; Rizkallah, E | 1 |
| Rantala, H; Tarkka, R; Uhari, M | 1 |
| Bazil, CW; Pedley, TA | 1 |
| Boothe, DM | 1 |
| Fiechtner, HB | 1 |
| Monnier, G; Moulin, T; Rumbach, L; Sevrin, C; Sevrin, P; Tatu, L | 1 |
| Czuczwar, SJ; Kleinrok, Z; Klonowski, P; Tutka, P | 1 |
| Gupta, YK; Malhotra, J | 1 |
| Hanson, GR; Jensen, M; Johnson, M; White, HS | 1 |
| Czuczwar, SJ; Haberek, G; Kleinrok, Z; Matyska, J; Pilip, S; Tomczyk, T; Turski, WA; Urbanska, EM | 1 |
| Heynen, T; Krupp, E; Li, XL; Post, RM; Weiss, SR | 1 |
| Beekman, M; Carter, RB; Gasior, M; Ungard, JT; Witkin, JM | 1 |
| Chen, Z; Fujii, Y; Ishizawa, K; Kamei, C; Okuma, C; Sugimoto, Y | 1 |
| Reddy, DS; Rogawski, MA | 2 |
| Mitchell, SC; Pollock, LM | 1 |
| Jagoda, A; Yoon, Y | 1 |
| Knudsen, FU | 1 |
| Sakai, K | 2 |
| Benson, PJ; Klein, EJ | 1 |
| Roffe, C | 1 |
| Temkin, NR | 1 |
| Aoyagi, Y; Ohta, A; Watanabe, Y; Yamada, K | 1 |
| Camfield, CS; Camfield, PR; Dooley, JM; Gordon, KE; MacSween, J | 1 |
| Autret-Leca, E; Jonville-Bera, AP; Ployet, JL | 1 |
| Gupta, YK; Srivastava, AK | 1 |
| Araujo, AP; Maia Filho, HS; Padua, PA | 1 |
| Gaman, OV; Glukhova, LIu; Maksimova, EV; Mironov, MB; Mukhin, KIu; Petrukhin, AA; Petrukhin, AS | 1 |
| Chen, KC; Chen, PS; Yang, MJ; Yang, YK; Yeh, TL | 1 |
| Koetter, KP; Maleck, WH; Petroianu, GA; Toomes, M | 1 |
| Polesin, A; Stern, M | 1 |
| Araki, H; Gomita, Y; Hashimoto, Y; Suemaru, K | 1 |
| Miyake, H; Nishihara, K; Tsuji, M; Tucker, A; Ukita, T | 1 |
| Li, S; Maeda, K; Matsumoto, K; Murakami, Y; Wang, M | 1 |
| Mehta, V; Singhi, P; Singhi, S | 1 |
| Mihajlovic-Madzarevic, V; Pappas, P | 1 |
| Dardis, C; Doherty, C; Farid, S | 1 |
| Nakazato, Y; Shimazu, K; Tamura, N | 1 |
| Kalita, J; Misra, UK; Nair, PP | 1 |
| Amonkou, AA; Brouh, Y; Ndjeundo, PG; Pete, Y; Tetchi, YD; Yapobi, Y | 1 |
| Domínguez-Fuentes, B; García-Arjona, R; García-Gil, D; Navarro-Navarro, J; Romero-Palacios, A; Sánchez-Crespo, JM | 1 |
| Kanemoto, K; Oshima, T; Tadokoro, Y | 1 |
| Chang, HR; Lai, YR; Lian, JD; Wu, SW | 1 |
| Chen, L; Feng, P; Liu, L; Wang, J; Zhou, D | 1 |
| Ahir, BK; Pratten, MK | 1 |
| Feifel, D; Melendez, G; Shilling, PD | 1 |
| Jasinarachchi, M; Rupasinghe, J | 1 |
| Benet, LZ; Grover, A | 1 |
| Chen, WB; Fan, CQ; Gao, R; Ren, Y; Su, YY; Wang, L; Zhang, YZ; Zhao, JW | 1 |
| Dürmüller, N; Porsolt, RD | 1 |
| Chen, Z; Liu, X; Ma, M; Su, L; Wu, Y | 1 |
| Addis, M; Bailey, K; Chanda, S; de Araujo Furtado, M; Lumley, LA; Moffett, M; Pak, T; Robertson, BD; Rossetti, F; Shields, M; Yourick, DL | 1 |
| Albus, K; Heinemann, U; Wahab, A | 1 |
| Bialer, M; Dudek, FE; Hen, N; Kaufmann, D; Nelson, C; Pouliot, W; Ricks, K; Roach, B; Shekh-Ahmad, T; Yagen, B | 1 |
| Choi, HC; Kang, TC; Kim, JE; Kim, YI; Lee, DS; Ryu, HJ; Song, HK | 1 |
| Awa, HD; Chelo, D; Kinkela, MN; Ndombo, PO | 1 |
| Baraban, SC; Dinday, MT; Hortopan, GA | 1 |
| Araki, Y; Hatano, K; Ishii, N; Terao, T | 1 |
| Lubszky, S; Reinhart, WH; Schulzki, T; Thöny, S | 1 |
| Bankstahl, M; Klein, S; Löscher, W | 1 |
| Afrikanova, T; Buenafe, OE; Crawford, AD; De Prins, A; de Witte, PA; Esguerra, CV; Kaminski, RM; Langlois, M; Leclercq, K; Rospo, CC; Smolders, I; Van Eeckhaut, A | 1 |
| Bamford, A; Clarke, A; Crowe, BH; Hacohen, Y; Lim, M; Lin, JP; Pullaperuma, SP; Sancho-Shimizu, V; Tudor-Williams, G; Vincent, A | 1 |
| Díaz, FV; Rasgado, LA; Reyes, GC | 1 |
| Löscher, W; Töllner, K; Twele, F | 1 |
| Chen, W; Chun, B; Gao, D; Jiang, M; Liu, G; Ren, G; Su, Y; Tian, F; Ye, H; Zhang, Y | 1 |
| Abe, K; Hashimura, M; Iha, HA; Iwai, C; Kato, M; Kawaji, S; Kawakita, K; Kunisawa, N; Ogawa, M; Ohno, Y; Shimizu, S | 1 |
| Buhl, DL; Duveau, V; Evrard, A; Gurrell, R; Mandé-Niedergang, B; Roucard, C; Ruggiero, C | 1 |
| Barker-Haliski, M; Knox, KM; Koneval, Z; Memon, A; White, HS; Zierath, DK | 1 |
| Ballardini, M; Carelli, C; Freni, F; Moretti, M; Morini, L; Vignali, C | 1 |
| García-Peñas, JJ; Gil Nagel-Rein, A; Sánchez-Carpintero, R; Villanueva-Haba, V | 1 |
| Dadi, FG; Ijigu, GM; Moges, BT; Semman, MF; Tesfaye, BT | 1 |
| Hume, AL; Lawal, OD; Meador, KJ; Wen, X | 1 |
| Chen, W; Huang, H; Jiang, M; Liu, G; Su, Y; Tian, F; Wang, Y; Zhang, Y | 1 |
34 review(s) available for valproic acid and diazepam
| Article | Year |
|---|---|
UDP-glucuronosyltransferases and clinical drug-drug interactions.
Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic | 2005 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Synthetic and therapeutic perspectives of nitrogen containing heterocycles as anti-convulsants.
Topics: Animals; Anticonvulsants; Heterocyclic Compounds; Humans; Molecular Structure; Seizures; Structure-Activity Relationship | 2020 |
Interactions with antiepileptic drugs.
Topics: Acetaminophen; Acetazolamide; Anti-Anxiety Agents; Anticoagulants; Anticonvulsants; Carbamazepine; Diazepam; Drug Interactions; Furosemide; Gonadal Steroid Hormones; Griseofulvin; Humans; Phenobarbital; Phenytoin; Primidone; Thiazines; Urea; Valproic Acid; Vitamin D | 1977 |
[Antiepileptics during pregnancy and lactation. Pharmacokinetic data].
Topics: Anticonvulsants; Bromides; Carbamazepine; Clonazepam; Diazepam; Ethosuximide; Female; Fetus; Humans; Kinetics; Lactation; Maternal-Fetal Exchange; Nitrazepam; Phenobarbital; Phenytoin; Pregnancy; Primidone; Valproic Acid | 1979 |
Pharmacological prophylaxis in the kindling model of epilepsy.
Topics: Amygdala; Anesthetics, Local; Animals; Antidepressive Agents, Tricyclic; Atropine; Aziridines; Carbamazepine; Catecholamines; Cats; Cerebral Cortex; Chlorpromazine; Clorazepate Dipotassium; Diazepam; Disease Models, Animal; Drug Evaluation, Preclinical; Epilepsy; Haplorhini; Hydroxydopamines; Phenobarbital; Phenytoin; Rats; Reserpine; Seizures; Valproic Acid | 1977 |
Clinical pharmacokinetics of anticonvulsants.
Topics: Administration, Oral; Adult; Aged; Aging; Animals; Anticonvulsants; Carbamazepine; Child; Clonazepam; Diazepam; Drug Interactions; Ethosuximide; Female; Humans; Hydantoins; Infant, Newborn; Injections, Intramuscular; Injections, Intravenous; Intestinal Absorption; Kidney Diseases; Kinetics; Liver Diseases; Milk; Molecular Biology; Phenobarbital; Phenytoin; Pregnancy; Primidone; Valproic Acid | 1976 |
Pharmacokinetics of rectal drug administration, Part I. General considerations and clinical applications of centrally acting drugs.
Topics: Administration, Rectal; Antiemetics; Atropine; Carbamazepine; Clonazepam; Delayed-Action Preparations; Diazepam; Flunitrazepam; Humans; Hydromorphone; Intestinal Absorption; Methadone; Methohexital; Midazolam; Morphine; Pharmacokinetics; Phenobarbital; Valproic Acid | 1991 |
Drugs acting on amino acid neurotransmitters.
Topics: Acoustic Stimulation; Amino Acids; Animals; Chemical Phenomena; Chemistry; Diazepam; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Humans; Hypoxia; Imidazoles; Isoxazoles; Mice; Mice, Inbred DBA; Muscimol; Myoclonus; Neurotransmitter Agents; Papio; Rats; Rats, Inbred Strains; Seizures; Valproic Acid | 1986 |
[Drug activation of GABAergic transmission in the central nervous system: benzodiazepines and GABAergic agonists].
Topics: Animals; Benzodiazepines; Benzodiazepinones; Brain; Carbolines; Chemical Phenomena; Chemistry; Cyclic GMP; Diazepam; Flumazenil; gamma-Aminobutyric Acid; Humans; Receptors, GABA-A; Synaptic Transmission; Valproic Acid | 1985 |
GABAergic control of anterior pituitary function in humans.
Topics: Adrenocorticotropic Hormone; Corticotropin-Releasing Hormone; Diazepam; Female; gamma-Aminobutyric Acid; Gonadotropin-Releasing Hormone; Growth Hormone; Growth Hormone-Releasing Hormone; Humans; Hyperprolactinemia; Hypothalamo-Hypophyseal System; Menstruation; Pituitary Gland, Anterior; Pituitary-Adrenal System; Receptors, GABA-A; Secretory Rate; Thyrotropin; Thyrotropin-Releasing Hormone; Valproic Acid | 1986 |
[The stiff-man syndrome].
Topics: Baclofen; Diazepam; Humans; Muscle Rigidity; Muscle Spasticity; Syndrome; Valproic Acid | 1987 |
Febrile seizures.
Topics: Child; Child, Preschool; Diagnosis, Differential; Diazepam; Electroencephalography; Epilepsy; Female; Humans; Infant; Male; Nitrazepam; Phenobarbital; Risk Factors; Seizures, Febrile; Valproic Acid | 1987 |
[A valproic acid-diazepam combination as an alternative to neuroleptic treatment].
Topics: Adult; Aged; Aged, 80 and over; Bipolar Disorder; Diazepam; Drug Combinations; Female; Humans; Male; Middle Aged; Psychotic Disorders; Schizophrenia; Valproic Acid | 1988 |
Pharmacokinetics of anti-epileptic drugs in the dog: a review.
Topics: Animals; Anticonvulsants; Blood Proteins; Carbamazepine; Clonazepam; Diazepam; Dog Diseases; Dogs; Epilepsy; Ethosuximide; Kinetics; Phenobarbital; Phenytoin; Primidone; Species Specificity; Trimethadione; Valproic Acid | 1985 |
Prediction of the disposition of nine weakly acidic and six weakly basic drugs in humans from pharmacokinetic parameters in rats.
Topics: Animals; Antipyrine; Barbiturates; Biological Availability; Chlorpromazine; Diazepam; Drug Evaluation; Female; Half-Life; Humans; Kinetics; Male; Metabolic Clearance Rate; Pentazocine; Pharmaceutical Preparations; Phenylbutazone; Phenytoin; Propranolol; Quinidine; Rats; Species Specificity; Tissue Distribution; Tolbutamide; Valproic Acid; Warfarin | 1985 |
[Myoclonus induced by some benzodiazepines in the Papio papio. Comparison with myoclonus induced by intermittent light stimulation (author's transl)].
Topics: Allylglycine; Animals; Anti-Anxiety Agents; Apomorphine; Diazepam; Levodopa; Lorazepam; Myoclonus; Papio; Photic Stimulation; Serotonin; Valproic Acid | 1982 |
[Use of phenobarbital in febrile convulsive crisis].
Topics: Child, Preschool; Diazepam; Epilepsy; Humans; Infant; Nervous System Diseases; Phenobarbital; Recurrence; Risk; Seizures, Febrile; Valproic Acid | 1983 |
Therapy for status epilepticus.
Topics: Acetazolamide; Anesthesia; Anticonvulsants; Barbiturates; Chlormethiazole; Clonazepam; Diazepam; Ethosuximide; Humans; Lidocaine; Lorazepam; Paraldehyde; Phenobarbital; Phenytoin; Status Epilepticus; Valproic Acid | 1983 |
Treatment of mood disorders with antiepileptic medications: clinical and theoretical implications.
Topics: Anticonvulsants; Bipolar Disorder; Carbamazepine; Clinical Trials as Topic; Clonazepam; Depressive Disorder; Diazepam; Double-Blind Method; Humans; Phenytoin; Valproic Acid | 1983 |
Clinical pharmacokinetics of antiepileptic drugs in adults.
Topics: Adult; Aging; Anticonvulsants; Carbamazepine; Clonazepam; Diazepam; Disease; Ethosuximide; Female; Humans; Kinetics; Phenobarbital; Phenytoin; Pregnancy; Primidone; Saliva; Valproic Acid | 1980 |
Pharmacological principles in the long-term treatment of epilepsy.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Diazepam; Epilepsy; Ethosuximide; Humans; Kinetics; Long-Term Care; Phenobarbital; Phenytoin; Primidone; Succinimides; Valproic Acid | 1981 |
New drug therapy for acute seizure management.
Topics: Acute Disease; Anticonvulsants; Child; Diazepam; Epilepsy; Humans; Phenytoin; Prodrugs; Seizures; Valproic Acid | 1997 |
A meta-analytic review of the preventive treatment of recurrences of febrile seizures.
Topics: Anticonvulsants; Chi-Square Distribution; Child; Diazepam; Drug Administration Schedule; Fever; Humans; Odds Ratio; Phenobarbital; Phenytoin; Pyridoxine; Randomized Controlled Trials as Topic; Recurrence; Risk Assessment; Seizures, Febrile; Valproic Acid | 1997 |
Advances in the medical treatment of epilepsy.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Diazepam; Drug Approval; Drug Design; Drug Interactions; Drug Resistance; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Injections, Intravenous; Ketones; Lamotrigine; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Phenylcarbamates; Phenytoin; Prodrugs; Propylene Glycols; Tiagabine; Topiramate; Triazines; United States; Valproic Acid; Vigabatrin | 1998 |
Anticonvulsant therapy in small animals.
Topics: Acetates; Amines; Animals; Anticonvulsants; Bromides; Clonazepam; Clorazepate Dipotassium; Cyclohexanecarboxylic Acids; Diazepam; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Mephenytoin; Pentobarbital; Phenobarbital; Phenylcarbamates; Phenytoin; Primidone; Propylene Glycols; Seizures; Valproic Acid | 1998 |
New antiepileptic drugs and preparations.
Topics: Acetates; Administration, Rectal; Age Factors; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Diazepam; Drug Overdose; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Injections, Intravenous; Lamotrigine; Phenylcarbamates; Phenytoin; Propylene Glycols; Topiramate; Triazines; Valproic Acid | 2000 |
[Febrile convulsions, Treatment and prognosis].
Topics: Analgesics, Non-Narcotic; Anticonvulsants; Child, Preschool; Diazepam; Epilepsy; Humans; Infant; Phenobarbital; Primidone; Prognosis; Recurrence; Seizures, Febrile; Time Factors; Valproic Acid | 2001 |
[Stiff-man syndrome].
Topics: Autoantibodies; Diabetes Mellitus, Type 1; Diagnosis, Differential; Diazepam; GABA Agents; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Humans; Prognosis; Stiff-Person Syndrome; Valproic Acid | 2000 |
Antiepileptogenesis and seizure prevention trials with antiepileptic drugs: meta-analysis of controlled trials.
Topics: Anticonvulsants; Brain Diseases; Brain Injuries; Carbamazepine; Controlled Clinical Trials as Topic; Diazepam; Epilepsy; Humans; Lorazepam; Models, Statistical; Phenobarbital; Phenytoin; Randomized Controlled Trials as Topic; Risk; Seizures; Treatment Outcome; Valproic Acid | 2001 |
[Stiff-person syndrome].
Topics: Animals; Autoantibodies; Autoimmunity; Diabetes Mellitus, Type 1; Diagnosis, Differential; Diazepam; GABA Agents; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Humans; Motor Neurons; Nerve Tissue Proteins; Prognosis; Stiff-Person Syndrome; Synaptic Transmission; Valproic Acid | 2002 |
[Diagnosis and treatment of epilepsy in the field of psychiatry].
Topics: Adult; Anticonvulsants; Carbamazepine; Diazepam; Electroencephalography; Epilepsy; Female; Humans; Male; Middle Aged; Psychiatry; Treatment Outcome; Valproic Acid | 2008 |
A systematic review of randomized controlled trials on the theraputic effect of intravenous sodium valproate in status epilepticus.
Topics: Anticonvulsants; Diazepam; Humans; Injections, Intravenous; Levetiracetam; Phenytoin; Piracetam; Randomized Controlled Trials as Topic; Status Epilepticus; Valproic Acid | 2012 |
Cannabidiol for the treatment of Lennox-Gastaut syndrome and Dravet syndrome: experts' recommendations for its use in clinical practice in Spain.
Topics: Anticonvulsants; Cannabidiol; Clobazam; Clonazepam; Diazepam; Dioxolanes; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Epilepsies, Myoclonic; Humans; Lennox Gastaut Syndrome; Phenobarbital; Practice Guidelines as Topic; Pyrrolidinones; Spain; Triazoles; Valproic Acid | 2021 |
13 trial(s) available for valproic acid and diazepam
| Article | Year |
|---|---|
Intermittent prophylaxis in febrile convulsions: diazepam or valproic acid?
Topics: Diazepam; Female; Humans; Infant; Male; Prospective Studies; Randomized Controlled Trials as Topic; Recurrence; Seizures, Febrile; Valproic Acid | 1990 |
Intention to treat febrile convulsions with rectal diazepam, valproate or phenobarbitone.
Topics: Administration, Rectal; Child; Child, Preschool; Diazepam; Female; Humans; Infant; Male; Phenobarbital; Risk Factors; Seizures, Febrile; Valproic Acid | 1989 |
Does sodium valproate increase clinical effects of diazepam? Double blind study.
Topics: Anti-Anxiety Agents; Anxiety; Diazepam; Double-Blind Method; Drug Interactions; Humans; Valproic Acid | 1989 |
Effects of sodium valproate and diazepam on beta-endorphin, beta-lipotropin and cortisol secretion induced by hypoglycemic stress in humans.
Topics: Adult; beta-Endorphin; beta-Lipotropin; Diazepam; Endorphins; Female; Humans; Hydrocortisone; Hypoglycemia; Hypothalamo-Hypophyseal System; Pituitary-Adrenal System; Receptors, GABA-A; Stress, Physiological; Valproic Acid | 1986 |
Prophylactic treatment with valproic acid or diazepam in children with febrile convulsions.
Topics: Child; Child, Preschool; Clinical Trials as Topic; Diazepam; Female; Humans; Infant; Male; Recurrence; Risk; Seizures, Febrile; Valproic Acid | 1986 |
[Preventing the recurrence of febrile seizures: intermittent prevention with rectal diazepam compared with continuous treatment with sodium valproate].
Topics: Administration, Rectal; Adolescent; Adult; Child; Diazepam; Drug Administration Schedule; Female; Humans; Male; Seizures, Febrile; Valproic Acid | 1987 |
Therapeutic effects of GABA-ergic drugs in affective disorders. A preliminary report.
Topics: Adolescent; Adult; Analgesics; Anticonvulsants; Bipolar Disorder; Carbamazepine; Clinical Trials as Topic; Diazepam; Double-Blind Method; Female; gamma-Aminobutyric Acid; Humans; Isoxazoles; Male; Middle Aged; Mood Disorders; Oxazoles; Oxcarbazepine; Schizophrenia; Valproic Acid | 1983 |
Treatment of mood disorders with antiepileptic medications: clinical and theoretical implications.
Topics: Anticonvulsants; Bipolar Disorder; Carbamazepine; Clinical Trials as Topic; Clonazepam; Depressive Disorder; Diazepam; Double-Blind Method; Humans; Phenytoin; Valproic Acid | 1983 |
Intravenous sodium valproate versus diazepam infusion for the control of refractory status epilepticus in children: a randomized controlled trial.
Topics: Anticonvulsants; Child; Child, Preschool; Diazepam; Female; Humans; Hypotension; Infant; Infusions, Intravenous; Male; Respiration, Artificial; Respiratory Insufficiency; Status Epilepticus; Time Factors; Treatment Outcome; Valproic Acid; Vasoconstrictor Agents | 2007 |
Intravenous sodium valproate in mainland China for the treatment of diazepam refractory convulsive status epilepticus.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Child; Child, Preschool; China; Diazepam; Female; Humans; Injections, Intravenous; Male; Middle Aged; Prospective Studies; Status Epilepticus; Time Factors; Valproic Acid; Young Adult | 2009 |
Valproate versus diazepam for generalized convulsive status epilepticus: a pilot study.
Topics: Adult; Aged; Anticonvulsants; Cerebrovascular Disorders; Diazepam; Drug Resistance; Electroencephalography; Emergencies; Encephalitis, Viral; Epilepsy; Female; Humans; Hypotension; Infusions, Intravenous; Male; Middle Aged; Pilot Projects; Respiratory Insufficiency; Status Epilepticus; Treatment Outcome; Valproic Acid; Young Adult | 2011 |
Phenobarbital Versus Valproate for Generalized Convulsive Status Epilepticus in Adults: A Prospective Randomized Controlled Trial in China.
Topics: Administration, Intravenous; Adult; Anticonvulsants; China; Diazepam; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Prospective Studies; Status Epilepticus; Treatment Outcome; Valproic Acid | 2016 |
Long-term follow-up of phenobarbital versus valproate for generalized convulsive status epilepticus in adults: A randomized clinical trial.
Topics: Adult; Anticonvulsants; Diazepam; Follow-Up Studies; Humans; Phenobarbital; Status Epilepticus; Treatment Outcome; Valproic Acid | 2023 |
185 other study(ies) available for valproic acid and diazepam
| Article | Year |
|---|---|
2-Phenyl-3H-imidazo[4,5-b]pyridine-3-acetamides as non-benzodiazepine anticonvulsants and anxiolytics.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Anxiety; Benzodiazepines; Binding, Competitive; Cerebral Cortex; gamma-Aminobutyric Acid; Imidazoles; Mice; Mice, Inbred ICR; Molecular Structure; Pyridines; Rats; Receptors, GABA-A; Seizures | 1991 |
2,4-Dihydro-3H-1,2,4-triazol-3-ones as anticonvulsant agents.
Topics: Animals; Anticonvulsants; Chemical Phenomena; Chemistry, Physical; Gerbillinae; Hippocampus; Hypoxia; Male; Mice; Neurons; Phencyclidine; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Triazoles | 1990 |
Functional group contributions to drug-receptor interactions.
Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship | 1984 |
5-Aryl-3-(alkylthio)-4H-1,2,4-triazoles as selective antagonists of strychnine-induced convulsions and potential antispastic agents.
Topics: Animals; Anticonvulsants; Cerebellum; Cerebral Cortex; Chlorides; Electroshock; Flumazenil; Male; Mice; Molecular Structure; Muscle Spasticity; Paralysis; Rats; Rats, Sprague-Dawley; Seizures; Structure-Activity Relationship; Strychnine; Triazoles | 1994 |
Synthesis and anticonvulsant activity of a new class of 2-[(arylalky)amino]alkanamide derivatives.
Topics: Alanine; Animals; Anticonvulsants; Benzylamines; Bicuculline; Drug Design; Electroshock; Indicators and Reagents; Male; Mice; Mice, Inbred ICR; Models, Molecular; Molecular Structure; Motor Activity; Picrotoxin; Postural Balance; Rats; Rats, Inbred Strains; Seizures; Structure-Activity Relationship; Strychnine | 1998 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs.
Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization | 2008 |
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility | 2010 |
In silico assay for assessing phospholipidosis potential of small druglike molecules: training, validation, and refinement using several data sets.
Topics: Animals; Cattle; Cells, Cultured; Computer Simulation; Cornea; Drug-Related Side Effects and Adverse Reactions; Fibroblasts; Lipidoses; Lysosomal Storage Diseases; Models, Molecular; Pharmaceutical Preparations; Phospholipids; Structure-Activity Relationship; Thermodynamics | 2012 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Structure-anticonvulsant activity studies in the group of (E)-N-cinnamoyl aminoalkanols derivatives monosubstituted in phenyl ring with 4-Cl, 4-CH
Topics: Amino Alcohols; Animals; Anticonvulsants; Crystallography, X-Ray; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Mice; Models, Molecular; Molecular Structure; Rats; Seizures; Structure-Activity Relationship | 2017 |
[Adverse effects of anti-epileptic drugs].
Topics: Adrenocorticotropic Hormone; Anticonvulsants; Barbiturates; Carbamazepine; Diazepam; Epilepsy; Ethosuximide; Humans; Mephenytoin; Nitrazepam; Phenytoin; Primidone; Succinimides; Thiazines; Trimethadione; Valproic Acid | 1975 |
[Antiepileptics used currently].
Topics: Anticonvulsants; Barbiturates; Carbamazepine; Clonazepam; Diazepam; Humans; Hydantoins; Primidone; Succinimides; Valproic Acid | 1979 |
Changes in sensitivity of mice to anticonvulsant drugs following bilateral olfactory bulb ablations.
Topics: Acetazolamide; Animals; Anticonvulsants; Chlordiazepoxide; Diazepam; Dose-Response Relationship, Drug; Electroshock; Male; Mice; Nitrazepam; Olfactory Bulb; Phenobarbital; Phenylacetates; Phenytoin; Trimethadione; Urea; Valproic Acid | 1977 |
Effect of anticonvulsants on thalamic afterdischarge in rats and cats.
Topics: Acetazolamide; Animals; Anticonvulsants; Carbamazepine; Cats; Diazepam; Electrocardiography; Electroencephalography; Female; Male; Phenobarbital; Phenytoin; Rats; Thalamus; Trimethadione; Valproic Acid | 1977 |
Drugs for epilepsy.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Diazepam; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Status Epilepticus; Valproic Acid | 1979 |
Effect of anticonvulsants on spiking activity induced by cortical freezing in cats.
Topics: Acetazolamide; Animals; Anticonvulsants; Arousal; Carbamazepine; Cats; Diazepam; Electrocardiography; Electroencephalography; Female; Freezing; Gallamine Triethiodide; Immobilization; Male; Phenobarbital; Phenytoin; Taurine; Trimethadione; Valproic Acid; Visual Cortex | 1979 |
The effect of methysergide, pimozide, and sodium valproate on the diazepam-stimulated growth hormone secretion in man.
Topics: Adult; Diazepam; Growth Hormone; Humans; Kinetics; Male; Methysergide; Pimozide; Time Factors; Valproic Acid | 1979 |
Anticonvulsant therapy in childhood. Recent advances.
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Diazepam; Humans; Phenobarbital; Phenytoin; Valproic Acid | 1979 |
Recent advances in drug therapy of some forms of childhood epilepsy.
Topics: Anticonvulsants; Carbamazepine; Child; Clonazepam; Diazepam; Drug Therapy, Combination; Epilepsy; Humans; Valproic Acid | 1979 |
Effect of anticonvulsants on cortical focal seizure in cats.
Topics: Acetazolamide; Animals; Anticonvulsants; Carbamazepine; Cats; Diazepam; Electrocardiography; Epilepsies, Partial; Female; Heart; Male; Phenobarbital; Phenytoin; Seizures; Trimethadione; Valproic Acid | 1977 |
[GABA-ergic mechanism of action of diazepam on cerebral cortex neurons].
Topics: Aminobutyrates; Animals; Bicuculline; Brain Chemistry; Diazepam; Evoked Potentials; GABA Antagonists; Male; Neurons; Rats; Semicarbazides; Somatosensory Cortex; Valproic Acid | 1976 |
Proposals on antiepileptic pharmacotherapy for use in developing countries.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Clonazepam; Developing Countries; Diazepam; Epilepsy; Ethosuximide; Humans; Infant; Phenobarbital; Phenytoin; Valproic Acid | 1976 |
Letter: Sodium valproate in the treatment of intractable childhood epilepsy.
Topics: Diazepam; Drug Therapy, Combination; Epilepsy; Phenobarbital; Phenytoin; Primidone; Pyridoxine; Valerates; Valproic Acid | 1975 |
[Multiple system atrophy with macro square wave jerks and pendular nystagmus].
Topics: Atrophy; Baclofen; Brain Diseases; Diazepam; Electrooculography; Eye Movements; Female; Humans; Middle Aged; Nystagmus, Pathologic; Phenobarbital; Saccades; Valproic Acid | 1992 |
Intravenous valproate: onset and duration of anticonvulsant activity against a series of electroconvulsions in comparison with diazepam and phenytoin.
Topics: Animals; Anticonvulsants; Diazepam; Electric Stimulation; Electroshock; Epilepsy, Tonic-Clonic; Injections, Intravenous; Male; Mice; Phenytoin; Seizures; Valproic Acid | 1992 |
Tolerance to the anticonvulsant effects of carbamazepine, diazepam, and sodium valproate in kindled rats.
Topics: Amygdala; Animals; Anticonvulsants; Brain; Carbamazepine; Diazepam; Drug Tolerance; Electrodes, Implanted; Kindling, Neurologic; Male; Rats; Seizures; Valproic Acid | 1992 |
Contingent tolerance to the anticonvulsant effects of carbamazepine, diazepam, and sodium valproate in kindled rats.
Topics: Amygdala; Animals; Anticonvulsants; Carbamazepine; Diazepam; Drug Tolerance; Electrodes; Kindling, Neurologic; Male; Rats; Stereotaxic Techniques; Valproic Acid | 1992 |
[Effect of anticonvulsants upon experimental limbic seizure status and regional cerebral blood flow in the hippocampus].
Topics: Animals; Anticonvulsants; Cats; Diazepam; Electroencephalography; Hippocampus; Isoxazoles; Phenobarbital; Phenytoin; Regional Blood Flow; Status Epilepticus; Valproic Acid; Zonisamide | 1992 |
Antiepileptic drugs delay the onset of seizures induced by aminophylline in conscious rats.
Topics: Aminophylline; Anesthesia; Animals; Anticonvulsants; Carbamazepine; Consciousness; Diazepam; Electroencephalography; Female; Infusions, Intravenous; Male; Pentobarbital; Rats; Rats, Inbred Strains; Seizures; Valproic Acid | 1992 |
Interactions between angiotensin II, diazepam, clonazepam and di-n-propylacetate in pentylenetetrazol kindling seizures in mice.
Topics: Angiotensin II; Animals; Clonazepam; Diazepam; Drug Interactions; Electric Stimulation; Ionophores; Kindling, Neurologic; Male; Pentylenetetrazole; Rats; Rats, Inbred Strains; Receptors, GABA-A; Seizures; Valproic Acid | 1991 |
"In vivo" administration of valproate decreases t-[35S]butylbicyclophosphorothionate binding in the rat brain.
Topics: Animals; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Depression, Chemical; Diazepam; Kinetics; Male; Membranes; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sulfur Radioisotopes; Valproic Acid | 1991 |
Effects of pharmacological manipulation on neurotransmitter and other amino acid levels in the CSF of the Senegalese baboon Papio papio.
Topics: Amino Acids; Animals; Diazepam; Dizocilpine Maleate; Electroshock; Hemolysis; Humans; Ketamine; Neurotransmitter Agents; Papio; Phencyclidine; Reference Values; Valproic Acid | 1991 |
GABAmimetic agents display anxiolytic-like effects in the social interaction and elevated plus maze procedures.
Topics: Aminooxyacetic Acid; Animals; Anti-Anxiety Agents; Conflict, Psychological; Diazepam; Exploratory Behavior; gamma-Aminobutyric Acid; Isonicotinic Acids; Isoxazoles; Male; Muscimol; Rats; Rats, Inbred Strains; Social Behavior; Valproic Acid | 1991 |
Effect of valproic acid, its unsaturated metabolites and some structurally related fatty acids on the binding of warfarin and dansylsarcosine to human albumin.
Topics: Binding Sites; Binding, Competitive; Dansyl Compounds; Diazepam; Fatty Acids; Fatty Acids, Unsaturated; Humans; In Vitro Techniques; Phenylbutazone; Protein Binding; Sarcosine; Serum Albumin; Structure-Activity Relationship; Valproic Acid; Warfarin | 1991 |
Wild running and switch-off behavior elicited by electrical stimulation of the inferior colliculus: effect of anticonvulsant drugs.
Topics: Animals; Anticonvulsants; Behavior, Animal; Conditioning, Operant; Diazepam; Electric Stimulation; Inferior Colliculi; Male; Motivation; Phenytoin; Rats; Rats, Inbred Strains; Running; Valproic Acid | 1991 |
Treatment of panic disorder and benzodiazepine withdrawal with valproate.
Topics: Adult; Agoraphobia; Clonazepam; Diazepam; Dose-Response Relationship, Drug; Humans; Male; Panic Disorder; Substance Withdrawal Syndrome; Substance-Related Disorders; Valproic Acid | 1991 |
Effects of pharmacological manipulation of GABAergic neurotransmission in a new mutant hamster model of paroxysmal dystonia.
Topics: Animals; Baclofen; Carbamazepine; Cricetinae; Diazepam; Disease Models, Animal; Dystonia; gamma-Aminobutyric Acid; Mesocricetus; Mutation; Pentylenetetrazole; Phenobarbital; Phenytoin; Synaptic Transmission; Valproic Acid | 1991 |
Effect of selective bilateral destruction of the substantia nigra on antiepileptic drug actions in kindled rats.
Topics: Amygdala; Animals; Anticonvulsants; Carbamazepine; Cerebral Cortex; Diazepam; Electrodes; Female; gamma-Aminobutyric Acid; Ibotenic Acid; Kindling, Neurologic; Phenobarbital; Rats; Rats, Inbred Strains; Substantia Nigra; Synaptic Transmission; Valproic Acid | 1990 |
"Ex vivo" binding of 35S-TBPS as a tool to study the pharmacology of GABAA receptors.
Topics: Alprazolam; Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Convulsants; Diazepam; Drug Synergism; Ethanol; In Vitro Techniques; Isoniazid; Male; Protein Conformation; Rats; Rats, Inbred Strains; Receptors, GABA-A; Stress, Physiological; Sulfur Radioisotopes; Valproic Acid | 1990 |
Kindling from stimulation of a highly sensitive locus in the posterior part of the piriform cortex. Comparison with amygdala kindling and effects of antiepileptic drugs.
Topics: Amygdala; Animals; Anticonvulsants; Carbamazepine; Cerebral Cortex; Diazepam; Electric Stimulation; Electrodes, Implanted; Female; Kindling, Neurologic; Phenobarbital; Rats; Rats, Inbred Strains; Valproic Acid | 1991 |
PIVKA-II (protein induced by vitamin K absence-II) status in newborns exposed to anticonvulsant drugs in utero.
Topics: Adult; Anticonvulsants; Biomarkers; Diazepam; Epilepsy; Factor VII; Factor X; Female; Humans; Infant, Newborn; Pregnancy; Pregnancy Complications; Protein Precursors; Prothrombin; Valproic Acid; Vitamin K Deficiency | 1991 |
Differential effects of agents enhancing purinergic transmission upon the antielectroshock efficacy of carbamazepine, diphenylhydantoin, diazepam, phenobarbital, and valproate in mice.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Anticonvulsants; Body Temperature Regulation; Diazepam; Electroshock; Female; Mice; Phenylisopropyladenosine; Receptors, Purinergic; Seizures; Valproic Acid | 1990 |
Inhibition of aminophylline-induced convulsions in mice by antiepileptic drugs and other agents.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Aminophylline; Animals; Anticonvulsants; Aspartic Acid; Diazepam; Female; Mice; N-Methylaspartate; Phenobarbital; Seizures; Synaptic Transmission; Valproic Acid | 1987 |
Brain neurotransmitter systems mediating behavioral deficits produced by inescapable shock treatment in rats.
Topics: Alanine; Amphetamine; Animals; Antidepressive Agents; Atropine; Brain; Desipramine; Diazepam; Electroshock; Escape Reaction; Male; Motor Activity; Neurotransmitter Agents; Physostigmine; Rats; Rats, Inbred Strains; Valproic Acid | 1988 |
Evidence for involvement of the astrocytic benzodiazepine receptor in the mechanism of action of convulsant and anticonvulsant drugs.
Topics: Animals; Anticonvulsants; Astrocytes; Barbiturates; Benzodiazepinones; Brain; Carbamazepine; Cells, Cultured; Convulsants; Diazepam; Ethosuximide; Mice; Neurons; Pentylenetetrazole; Phenobarbital; Picrotoxin; Receptors, GABA-A; Sesterterpenes; Trimethadione; Valproic Acid | 1988 |
[Effect of diazepam, carbamazepine, sodium valproate and their combinations with vitamin preparations on epileptic activity].
Topics: Animals; Anticonvulsants; Carbamazepine; Diazepam; Drug Therapy, Combination; Male; Niacinamide; Pentylenetetrazole; Pyridoxal Phosphate; Rats; Seizures; Valproic Acid; Vitamin E; Vitamins | 1985 |
Anticonvulsant drugs effective against human temporal lobe epilepsy prevent seizures but not neurotoxicity induced in rats by quinolinic acid: electroencephalographic, behavioral and histological assessments.
Topics: Animals; Anticonvulsants; Behavior, Animal; Carbamazepine; Chlorpromazine; Diazepam; Disease Models, Animal; Electroencephalography; Epilepsy, Temporal Lobe; Male; Phenobarbital; Phenytoin; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Seizures; Valproic Acid | 1986 |
Some anticonvulsant drugs alter monoamine-mediated behaviour in mice in ways similar to electroconvulsive shock; implications for antidepressant therapy.
Topics: 5-Hydroxytryptophan; Animals; Anticonvulsants; Antidepressive Agents; Apomorphine; Behavior, Animal; Biogenic Amines; Clonidine; Diazepam; Electroshock; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred C57BL; Motor Activity; Radioligand Assay; Receptors, Adrenergic, beta; Receptors, Serotonin; Valproic Acid | 1985 |
Non involvement of gamma-aminobutyric acid in catechol-induced seizures.
Topics: Animals; Carbachol; Diazepam; Female; gamma-Aminobutyric Acid; Mice; Muscles; Phenobarbital; Picrotoxin; Receptors, GABA-A; Seizures; Valproic Acid | 1986 |
The effects of beta-carboline carboxylic acid ethyl ester and its free acid, administered ICV, on the anticonvulsant activity of diazepam and sodium valproate in the mouse.
Topics: Animals; Benzodiazepinones; Carbolines; Diazepam; Drug Interactions; Female; Mice; Mice, Inbred C3H; Pentylenetetrazole; Receptors, GABA-A; Seizures; Valproic Acid | 1986 |
Development of tolerance to the anticonvulsant effect of GABAmimetic drugs in genetically epilepsy-prone gerbils.
Topics: Acetates; Alkynes; Aminocaproates; Aminooxyacetic Acid; Animals; Anticonvulsants; Brain; Diazepam; Drug Tolerance; Epilepsy; Female; gamma-Aminobutyric Acid; Gerbillinae; Isoxazoles; Male; Oxazoles; Valproic Acid | 1986 |
Modulation of the behavioral effects of anticonvulsant drugs by an external discriminative stimulus in the pigeon.
Topics: Animals; Anticonvulsants; Columbidae; Conditioning, Operant; Diazepam; Discrimination, Psychological; Dose-Response Relationship, Drug; Phenobarbital; Phenytoin; Probability; Reinforcement Schedule; Valproic Acid | 1986 |
Differential effects of valproic acid on the serum protein binding of lorazepam and diazepam.
Topics: Blood Proteins; Charcoal; Diazepam; Humans; In Vitro Techniques; Lorazepam; Protein Binding; Valproic Acid | 1986 |
Benzodiazepine cross-tolerance in mice extends to sodium valproate.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Clobazam; Clonazepam; Diazepam; Drug Tolerance; Lorazepam; Male; Mice; Pentylenetetrazole; Phenobarbital; Valproic Acid | 1986 |
Genetic differences in anticonvulsant sensitivity in mouse lines selectively bred for ethanol withdrawal severity.
Topics: Alcohol Withdrawal Delirium; Alcohols; Animals; Anticonvulsants; Diazepam; Disease Susceptibility; Electroshock; Mice; Mice, Inbred Strains; Phenobarbital; Phenytoin; Psychoses, Alcoholic; Valproic Acid | 1986 |
Evaluation of two anticonvulsant amino-pyridazine derivatives in the conflict test in rats.
Topics: Animals; Anticonvulsants; Conflict, Psychological; Diazepam; Flumazenil; Meprobamate; Mice; Papio; Pentobarbital; Pyrazoles; Pyridazines; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Valproic Acid | 1986 |
Inhibition of quisqualate-induced seizures by glutamic acid diethyl ester and anti-epileptic drugs.
Topics: Aminooxyacetic Acid; Animals; Anticonvulsants; Carbamazepine; Diazepam; Female; Glutamates; Mice; Oxadiazoles; Phenobarbital; Phenytoin; Quisqualic Acid; Seizures; Valproic Acid | 1986 |
[Benign epileptic infantile spasms].
Topics: Child, Preschool; Diazepam; Electroencephalography; Follow-Up Studies; Humans; Hydrocortisone; Infant; Intelligence; Spasms, Infantile; Valproic Acid | 1986 |
[Modification of psychophysical performance of the human by anticonvulsants].
Topics: Anticonvulsants; Arousal; Carbamazepine; Diazepam; Epilepsy; Ethosuximide; Humans; Mental Processes; Phenobarbital; Psychological Tests; Psychomotor Performance; Valproic Acid | 1987 |
The role of ultrasound in the early diagnosis of fetal structural defects following maternal anticonvulsant therapy.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Diazepam; Female; Humans; Infant, Newborn; Maternal-Fetal Exchange; Middle Aged; Phenobarbital; Phenytoin; Pregnancy; Prenatal Diagnosis; Prospective Studies; Ultrasonography; Valproic Acid | 1988 |
Antiepileptic drug evaluation in a new animal model: spontaneous petit mal epilepsy in the rat.
Topics: Animals; Anticonvulsants; Carbamazepine; Diazepam; Disease Models, Animal; Drug Evaluation, Preclinical; Electroencephalography; Epilepsy, Absence; Ethosuximide; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Trimethadione; Valproic Acid | 1985 |
[Effect of sodium valproate on brain levels of diazepam and N-desmethyldiazepam in the rat].
Topics: Animals; Brain Chemistry; Diazepam; Male; Nordazepam; Rats; Rats, Inbred Strains; Valproic Acid | 1985 |
An analysis of the in vivo interactions between chemical convulsants and anticonvulsants.
Topics: Animals; Anticonvulsants; Bicuculline; Convulsants; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; Mice; Pentylenetetrazole; Phenobarbital; Picrotoxin; Valproic Acid | 1985 |
The specific protective effect of diazepam and valproate against isoniazid-induced seizures is not correlated with increased GABA levels.
Topics: Amino Acids; Animals; Diazepam; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Isoniazid; Male; Mice; Mice, Inbred Strains; Seizures; Time Factors; Valproic Acid | 1985 |
Valproate increases diazepam impregnation selectively in CNS of the rat after subchronic administration.
Topics: Analysis of Variance; Animals; Blood Proteins; Brain; Cerebellum; Diazepam; Drug Interactions; Erythrocytes; Hippocampus; Male; Medulla Oblongata; Pons; Protein Binding; Rats; Rats, Inbred Strains; Tissue Distribution; Valproic Acid | 1985 |
Diazepam-induced place preference conditioning: appetitive and antiaversive properties.
Topics: Animals; Appetitive Behavior; Avoidance Learning; Cocaine; Conditioning, Operant; Convulsants; Diazepam; Male; Meprobamate; Naloxone; Picrotoxin; Pyrazoles; Rats; Rats, Inbred Strains; Valproic Acid | 1985 |
[Effect of lithium, carbamazepine, ca-valproate and diazepam on changes in social isolation-induced behavior in mice].
Topics: Aggression; Animals; Behavior, Animal; Carbamazepine; Diazepam; Lithium; Male; Mice; Motor Activity; Serotonin; Social Isolation; Stress, Physiological; Valproic Acid | 1985 |
[Effect of anticonvulsants on serum protein binding of 14C-diazepam].
Topics: Anticonvulsants; Binding, Competitive; Blood Proteins; Diazepam; Humans; Protein Binding; Valproic Acid | 1985 |
Seizure control following administration of anticonvulsant drugs in the quaking mouse.
Topics: Animals; Anticonvulsants; Carbamazepine; Diazepam; Ethosuximide; Mice; Mice, Inbred C57BL; Mice, Quaking; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 1985 |
Protective effects of diazepam and valproate on beta-vinyllactic acid-induced seizures.
Topics: Animals; Brain; Convulsants; Diazepam; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Lactates; Male; Mice; Seizures; Synaptic Transmission; Valproic Acid | 1984 |
Evidence that GABA mechanisms mediate the anxiolytic action of benzodiazepines: a study with valproic acid.
Topics: Animals; Anti-Anxiety Agents; Conflict, Psychological; Diazepam; Discrimination Learning; gamma-Aminobutyric Acid; Male; Pentylenetetrazole; Rats; Valproic Acid | 1980 |
[Role of the GABA-ergic link in the development of the tranquilizing effect in cats].
Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Brain; Brain Chemistry; Cats; Diazepam; gamma-Aminobutyric Acid; Male; Valproic Acid | 1981 |
Effect of treatment with sodium valproate and diazepam on plasma corticotropin in Nelson's syndrome.
Topics: Adrenocorticotropic Hormone; Adult; Depression, Chemical; Diazepam; Female; gamma-Aminobutyric Acid; Humans; Hypothalamus; Male; Middle Aged; Nelson Syndrome; Pituitary Neoplasms; Valproic Acid | 1981 |
[Anticonvulsant action of di-N-propylacetate combined with benzodiazepines, phenobarbital and phenytoin].
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Diazepam; Drug Therapy, Combination; Male; Mice; Pentylenetetrazole; Phenobarbital; Phenytoin; Seizures; Semicarbazides; Valproic Acid | 1981 |
Effect of valproic acid on [3H]diazepam and [3H]dihydropicrotoxinin binding sites at the benzodiazepine-GABA receptor-ionophore complex.
Topics: Animals; Binding, Competitive; Brain; Cell Membrane; Diazepam; Kinetics; Male; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A; Valproic Acid | 1981 |
Benzodiazepine antagonists abolish electrophysiological effects of sodium valproate in the rat.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Diazepam; Evoked Potentials, Visual; Female; Flumazenil; gamma-Aminobutyric Acid; Immobilization; Kinetics; Male; Rats; Receptors, Drug; Receptors, GABA-A; Valproic Acid | 1982 |
Effects of agents which enhance GABA-mediated neurotransmission on licking conflict in rats and exploration in mice.
Topics: Animals; Conflict, Psychological; Diazepam; Exploratory Behavior; Flunitrazepam; gamma-Aminobutyric Acid; Male; Mice; Muscimol; Nitrazepam; Rats; Rats, Inbred Strains; Synaptic Transmission; Urethane; Valproic Acid | 1982 |
The effects of kindling on GABA-mediated inhibition in the dentate gyrus of the rat. I. Paired-pulse depression.
Topics: Amygdala; Animals; Diazepam; gamma-Aminobutyric Acid; Hippocampus; Kindling, Neurologic; Male; Membrane Potentials; Muscimol; Neural Inhibition; Neural Pathways; Rats; Synaptic Transmission; Valproic Acid | 1983 |
DMCM: a potent convulsive benzodiazepine receptor ligand.
Topics: Animals; Carbolines; Convulsants; Diazepam; Drug Interactions; Female; Indoles; Lorazepam; Male; Mice; Pentylenetetrazole; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Seizures; Valproic Acid | 1983 |
A monkey model for status epilepticus: carbamazepine and valproate compared to three standard anticonvulsants.
Topics: Aluminum Hydroxide; Animals; Anticonvulsants; Carbamazepine; Diazepam; Macaca mulatta; Male; Phenobarbital; Phenytoin; Pyridoxine; Status Epilepticus; Valproic Acid | 1983 |
Regular and lasting neocortical spiking produced by systemic administration of a steroid derivative in the rat.
Topics: Action Potentials; Androstanes; Animals; Azasteroids; Behavior, Animal; Cerebral Cortex; Diazepam; Electroencephalography; Evoked Potentials, Visual; gamma-Aminobutyric Acid; Humans; Rats; Rats, Inbred Strains; Stereotyped Behavior; Steroids, Heterocyclic; Valproic Acid | 1983 |
Tonic status epilepticus presenting as confusional state.
Topics: Adolescent; Cognition Disorders; Confusion; Diazepam; Electroencephalography; Humans; Male; Methylphenidate; Phenobarbital; Phenytoin; Sleep; Status Epilepticus; Valproic Acid | 1983 |
Effects of valproic acid on spinal reflexes and [3H]muscimol and [3H]diazepam binding in brain membranes in rats.
Topics: Animals; Brain; Diazepam; Male; Membranes; Muscimol; Oxazoles; Rats; Rats, Inbred Strains; Reflex; Spinal Cord; Valproic Acid | 1983 |
Active metabolites in antiepileptic therapy. Reflections on a pharmacological joker.
Topics: Anticonvulsants; Biotransformation; Carbamazepine; Diazepam; Epilepsy; Humans; Kinetics; Primidone; Valproic Acid | 1983 |
High anticonvulsant potency of gamma-aminobutyric acid (GABA)mimetic drugs in gerbils with genetically determined epilepsy.
Topics: Alkynes; Aminocaproates; Aminooxyacetic Acid; Animals; Anticonvulsants; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Female; gamma-Aminobutyric Acid; Gerbillinae; Isoxazoles; Male; Mice; Seizures; Valproic Acid | 1983 |
Febrile convulsions.
Topics: Anticonvulsants; Child, Preschool; Diazepam; Female; Fever; Humans; Infant; Male; Phenobarbital; Recurrence; Seizures; Valproic Acid | 1983 |
Anticonvulsant potency of common antiepileptic drugs in the gerbil.
Topics: Animals; Anticonvulsants; Carbamazepine; Diazepam; Ethosuximide; Female; Gerbillinae; Male; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 1983 |
Microscale ultrafiltration technique for determining free drug in 50-microL serum samples.
Topics: Animals; Chloramphenicol; Diazepam; Furosemide; Humans; Indomethacin; Infant; Infant, Newborn; Microchemistry; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Ultrafiltration; Valproic Acid | 1984 |
Effects of some anticonvulsant drugs on brain GABA level and GAD and GABA-T activities.
Topics: 4-Aminobutyrate Transaminase; Animals; Anticonvulsants; Brain; Carbamazepine; Clonazepam; Diazepam; gamma-Aminobutyric Acid; Male; Mice; Oxidoreductases; Phenobarbital; Phenytoin; Valproic Acid | 1984 |
[Treatment of several psychotic states with the combination of valproic acid with diazepam].
Topics: Acute Disease; Adult; Delusions; Diazepam; Drug Therapy, Combination; Female; Hallucinations; Haloperidol; Humans; Male; Middle Aged; Schizophrenia, Paranoid; Valproic Acid | 1984 |
Effects of some gamma-aminobutyric acid (GABA)-ergic drugs on the dopaminergic control of human growth hormone secretion.
Topics: Adult; Apomorphine; Baclofen; Diazepam; Dopamine; gamma-Aminobutyric Acid; Growth Hormone; Humans; Levodopa; Male; Valproic Acid | 1980 |
Comparative effects of two commercially available blood collection tubes on plasma concentrations of drugs.
Topics: Acebutolol; Blood Specimen Collection; Carbamazepine; Diazepam; Digoxin; Ethosuximide; Humans; Nordazepam; Penbutolol; Pharmaceutical Preparations; Propranolol; Quinidine; Salicylates; Time Factors; Valproic Acid; Warfarin | 1980 |
[Termination of status epilepticus with sodium valproate].
Topics: Clonazepam; Diazepam; Humans; Infant; Phenytoin; Status Epilepticus; Valproic Acid | 1980 |
Prophylaxis and febrile convulsions.
Topics: Child; Child, Preschool; Diazepam; Epilepsy; Humans; Infant; Phenobarbital; Recurrence; Seizures; Seizures, Febrile; Valproic Acid | 1981 |
Effect of sodium dipropylacetate on conflict behavior in rats.
Topics: Animals; Conflict, Psychological; Diazepam; Male; Phenytoin; Punishment; Rats; Reward; Valproic Acid | 1980 |
Altered drug binding to serum proteins in pregnant women: therapeutic relevance.
Topics: Adult; Blood Proteins; Diazepam; Female; Humans; In Vitro Techniques; Phenytoin; Pregnancy; Pregnancy Trimester, Third; Protein Binding; Valproic Acid | 1981 |
Effects of some antiepileptic drugs in pentetrazol-induced convulsions in mice lesioned with kainic acid.
Topics: Acetazolamide; Animals; Anticonvulsants; Carbamazepine; Diazepam; Dose-Response Relationship, Drug; Hippocampus; Injections, Intraventricular; Kainic Acid; Male; Mice; Pentylenetetrazole; Phenobarbital; Pyrrolidines; Seizures; Succinimides; Trimethadione; Valproic Acid | 1981 |
Only certain anticonvulsants protect against kainate neurotoxicity.
Topics: Animals; Anticonvulsants; Diazepam; Kainic Acid; Male; Nervous System Diseases; Phenobarbital; Phenytoin; Pyrrolidines; Rats; Rats, Inbred Strains; Seizures; Valproic Acid | 1981 |
Serum protein binding of diazepam and its displacement by valproic acid in vitro.
Topics: Binding, Competitive; Diazepam; Epilepsy; Humans; In Vitro Techniques; Serum Albumin; Valproic Acid | 1981 |
[Stupor due to sodium valproate. Immediate arousal after intravenous diazepam (author's transl)].
Topics: Child; Diazepam; Electroencephalography; Humans; Injections, Intravenous; Male; Mental Disorders; Valproic Acid | 1981 |
Valproic acid and diazepam interaction in vivo.
Topics: Adult; Blood Proteins; Diazepam; Drug Interactions; Humans; Kinetics; Male; Nordazepam; Protein Binding; Valproic Acid | 1982 |
Effect of anticonvulsant drugs on kainic acid-induced epileptiform activity.
Topics: Animals; Anticonvulsants; Diazepam; Electroencephalography; Ethosuximide; Guinea Pigs; Hippocampus; Kainic Acid; Phenobarbital; Phenytoin; Pyrrolidines; Rats; Rats, Inbred Strains; Seizures; Valproic Acid | 1982 |
Comparative anticonvulsant activity and neurotoxicity of clobazam, diazepam, phenobarbital, and valproate in mice and rats.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Clobazam; Diazepam; Dose-Response Relationship, Drug; Electroshock; Lethal Dose 50; Male; Mice; Mice, Inbred Strains; Nervous System; Phenobarbital; Rats; Rats, Inbred Strains; Seizures; Valproic Acid | 1982 |
["Fever convulsions" in children. Current viewpoints on diagnosis, therapy and prognosis].
Topics: Child, Preschool; Diagnosis, Differential; Diazepam; Epilepsy; Humans; Infant; Parents; Phenobarbital; Seizures, Febrile; Spinal Puncture; Valproic Acid | 1982 |
[Treatment of febrile convulsions in infants].
Topics: Anticonvulsants; Diazepam; Humans; Infant; Recurrence; Seizures, Febrile; Valproic Acid | 1995 |
Effects of the peptide BCH-325 upon the efficacy of common antiepileptic drugs.
Topics: Amino Acid Sequence; Animals; Anticonvulsants; Carbamazepine; Diazepam; Drug Interactions; Endorphins; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred ICR; Molecular Sequence Data; Peptide Fragments; Phenobarbital; Phenytoin; Seizures; Sodium Channels; Synaptic Transmission; Valproic Acid | 1994 |
[Anticonvulsant and neurotoxic effects of various combinations of phenobarbital, diazepam, sodium valproate, and 1,4-dihydropyridine ryodipine].
Topics: Animals; Anticonvulsants; Diazepam; Drug Combinations; Drug Synergism; Mice; Nervous System; Nifedipine; Phenobarbital; Valproic Acid | 1994 |
Epilepsy treatment in The Netherlands. Comparison of matched groups of two medical centres.
Topics: Adolescent; Adult; Carbamazepine; Diazepam; Epilepsy; Ethosuximide; Female; gamma-Aminobutyric Acid; Humans; Male; Netherlands; Phenobarbital; Phenytoin; Primidone; Quality of Health Care; Statistics, Nonparametric; Treatment Outcome; Valproic Acid; Vigabatrin | 1994 |
[Effect of sodium valproate, phenobarbital and diazepam during their combined use on convulsions induced by electroshock in mice].
Topics: Animals; Diazepam; Drug Synergism; Drug Therapy, Combination; Electroshock; Mice; Phenobarbital; Seizures; Valproic Acid | 1993 |
Contact dermatitis from diazepoxides.
Topics: Adult; Cross Reactions; Dermatitis, Allergic Contact; Diazepam; Female; Hand Dermatoses; Humans; Valproic Acid | 1994 |
Effects of GABAergic drugs on ethanol-induced gastric lesions.
Topics: Animals; Baclofen; Bicuculline; Diazepam; Ethanol; GABA Antagonists; gamma-Aminobutyric Acid; Gastrointestinal Hemorrhage; Indomethacin; Male; Muscimol; Rats; Rats, Sprague-Dawley; Receptors, GABA; Valproic Acid | 1993 |
Search for an antidote to electroconvulsion and lethality in aminophylline-sensitized mice.
Topics: Aminophylline; Animals; Diazepam; Dizocilpine Maleate; Electroshock; Male; Mice; Seizures; Valproic Acid | 1993 |
Increasing-current electroshock seizure test: a new method for assessment of anti- and pro-convulsant activities of drugs in mice.
Topics: Analgesics, Opioid; Animals; Anticonvulsants; Carbamazepine; Convulsants; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation; Drug Interactions; Ear; Electrodes; Electroshock; Ethosuximide; Injections, Intravenous; Male; Mice; Morphine; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 1996 |
Lamotrigine potentiates the antiseizure activity of some anticonvulsants in DBA/2 mice.
Topics: Acoustic Stimulation; Animals; Anticonvulsants; Diazepam; Drug Synergism; Female; Lamotrigine; Male; Mice; Mice, Inbred DBA; Phenytoin; Seizures; Triazines; Valproic Acid | 1996 |
Protective effects of GABAergic drugs and other anticonvulsants in lithium-pilocarpine-induced status epilepticus.
Topics: Animals; Anticonvulsants; Baclofen; Clonazepam; Diazepam; Dizocilpine Maleate; Ethanol; GABA Agents; gamma-Aminobutyric Acid; Lithium Chloride; Male; Neuroprotective Agents; Pentobarbital; Phenobarbital; Phenytoin; Pilocarpine; Rats; Rats, Wistar; Status Epilepticus; Valproic Acid | 1996 |
Interspecies scaling: predicting pharmacokinetic parameters of antiepileptic drugs in humans from animals with special emphasis on clearance.
Topics: Animals; Anticonvulsants; Diazepam; Ethosuximide; Half-Life; Humans; Models, Biological; Species Specificity; Valproic Acid | 1996 |
GABAergic influences on plus-maze behaviour in mice.
Topics: Animals; Baclofen; Behavior, Animal; Bicuculline; Diazepam; GABA Modulators; Male; Mice; Mice, Inbred DBA; Muscimol; Nipecotic Acids; Oximes; Picrotoxin; Valproic Acid | 1996 |
New dosage forms for old anticonvulsants.
Topics: Anticonvulsants; Diazepam; Dosage Forms; Humans; Phenytoin; Valproic Acid | 1998 |
["Stiff-man" syndrome treated with intravenous immunoglobulins].
Topics: Diazepam; Humans; Immunoglobulins, Intravenous; Male; Middle Aged; Muscle Contraction; Stiff-Person Syndrome; Valproic Acid | 1998 |
N(G)-nitro-L-arginine impairs the anticonvulsive action of ethosuximide against pentylenetetrazol.
Topics: Animals; Anticonvulsants; Arginine; Convulsants; Diazepam; Drug Interactions; Enzyme Inhibitors; Ethosuximide; Male; Mice; Nitroarginine; Pentylenetetrazole; Phenobarbital; Psychomotor Performance; Seizures; Valproic Acid | 1999 |
Effect of theophylline on diazepam and sodium valproate protection in pentylenetetrazole - kindled seizures in rats.
Topics: Animals; Anticonvulsants; Convulsants; Diazepam; Drug Interactions; Male; Pentylenetetrazole; Protective Agents; Rats; Rats, Wistar; Seizures; Theophylline; Valproic Acid | 1997 |
Distinct features of seizures induced by cocaine and amphetamine analogs.
Topics: Animals; Central Nervous System Agents; Central Nervous System Stimulants; Diazepam; Dose-Response Relationship, Drug; Flunarizine; Hallucinogens; Male; Methamphetamine; Mice; N-Methyl-3,4-methylenedioxyamphetamine; Oxazoles; Rats; Rats, Sprague-Dawley; Seizures; Time Factors; Valproic Acid | 1999 |
NMDA- but not kainate-mediated events reduce efficacy of some antiepileptic drugs against generalized tonic-clonic seizures in mice.
Topics: Animals; Anticonvulsants; Carbamazepine; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Electroshock; Epilepsy, Tonic-Clonic; Kainic Acid; Male; Mice; N-Methylaspartate; Phenobarbital; Phenytoin; Receptors, N-Methyl-D-Aspartate; Valproic Acid | 1999 |
Tolerance to the anticonvulsant effects of lamotrigine on amygdala kindled seizures: cross-tolerance to carbamazepine but not valproate or diazepam.
Topics: Amygdala; Animals; Anticonvulsants; Carbamazepine; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Drug Tolerance; Electric Stimulation; Electrodes, Implanted; Kindling, Neurologic; Lamotrigine; Male; Rats; Rats, Sprague-Dawley; Seizures; Triazines; Valproic Acid | 2000 |
Acute and chronic effects of the synthetic neuroactive steroid, ganaxolone, against the convulsive and lethal effects of pentylenetetrazol in seizure-kindled mice: comparison with diazepam and valproate.
Topics: Animals; Anticonvulsants; Convulsants; Diazepam; Dose-Response Relationship, Drug; Kindling, Neurologic; Male; Mice; Motor Activity; Pentylenetetrazole; Pregnanolone; Seizures; Stereotypic Movement Disorder; Valproic Acid | 2000 |
Participation of GABAergic and histaminergic systems in inhibiting amygdaloid kindled seizures.
Topics: Amygdala; Animals; Bicuculline; Diazepam; gamma-Aminobutyric Acid; Histamine; Imidazoles; Kindling, Neurologic; Male; Muscimol; Rats; Rats, Wistar; Seizures; Thiourea; Valproic Acid | 2000 |
Enhanced anticonvulsant activity of ganaxolone after neurosteroid withdrawal in a rat model of catamenial epilepsy.
Topics: Animals; Anticonvulsants; Convulsants; Diazepam; Disease Models, Animal; Enzyme Inhibitors; Epilepsy; Female; Finasteride; Menstruation; Oxidoreductases; Pentylenetetrazole; Pregnanolone; Pseudopregnancy; Rats; Rats, Sprague-Dawley; Seizures; Steroids; Valproic Acid | 2000 |
Nonconvulsive status epilepticus causing acute confusion.
Topics: Acute Disease; Aged; Anticonvulsants; Confusion; Diazepam; Epilepsy, Generalized; Fatal Outcome; Female; Humans; Valproic Acid | 2000 |
Anxiolytic effects of valproate and diazepam in mice are differentially sensitive to picrotoxin antagonism.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Decision Making; Diazepam; Exploratory Behavior; GABA Antagonists; Male; Mice; Mice, Inbred DBA; Motor Activity; Picrotoxin; Valproic Acid | 2001 |
New-onset absence status epilepsy presenting as altered mental status in a pediatric patient.
Topics: Anticonvulsants; Child; Diagnosis, Differential; Diazepam; Drug Therapy, Combination; Electroencephalography; Epilepsy, Absence; Female; Fructose; Humans; Mental Status Schedule; Topiramate; Valproic Acid | 2001 |
Nonconvulsive status epilepticus causing acute confusion.
Topics: Aged; Anti-Anxiety Agents; Diazepam; Female; Humans; Neuroleptic Malignant Syndrome; Status Epilepticus; Valproic Acid | 2001 |
Enhanced anticonvulsant activity of neuroactive steroids in a rat model of catamenial epilepsy.
Topics: Allosteric Regulation; Animals; Anticonvulsants; Benzodiazepinones; Desoxycorticosterone; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Epilepsy; Female; Menstrual Cycle; Pentylenetetrazole; Phenobarbital; Pregnanolone; Pseudopregnancy; Rats; Rats, Sprague-Dawley; Receptors, GABA; Steroids; Substance Withdrawal Syndrome; Valproic Acid | 2001 |
Effect of alkylpyrazine derivatives on the duration of pentobarbital-induced sleep, picrotoxicin-induced convulsion and gamma-aminobutyric acid (GABA) levels in the mouse brain.
Topics: Aminooxyacetic Acid; Animals; Anticonvulsants; Bicuculline; Brain Chemistry; Convulsants; Diazepam; GABA Agents; GABA Antagonists; gamma-Aminobutyric Acid; Hypnotics and Sedatives; Injections, Intraventricular; Male; Mice; Pentobarbital; Picrotoxin; Pyrazines; Seizures; Sleep; Time Factors; Valproic Acid | 2001 |
Treatment of febrile seizures: the influence of treatment efficacy and side-effect profile on value to parents.
Topics: Adult; Anticonvulsants; Anxiety; Attitude; Child, Preschool; Diazepam; Educational Status; Female; Humans; Income; Infant; Male; Parents; Phenobarbital; Secondary Prevention; Seizures, Febrile; Surveys and Questionnaires; Treatment Outcome; Valproic Acid | 2001 |
[Treatment of febrile convulsions].
Topics: Age Factors; Analgesics, Non-Narcotic; Anticonvulsants; Carbamazepine; Child, Preschool; Diazepam; Double-Blind Method; Female; Humans; Infant; Male; Phenobarbital; Phenytoin; Prospective Studies; Randomized Controlled Trials as Topic; Recurrence; Risk Factors; Seizures, Febrile; Time Factors; Valproic Acid | 2002 |
Aspirin modulates the anticonvulsant effect of diazepam and sodium valproate in pentylenetetrazole and maximal electroshock induced seizures in mice.
Topics: Animals; Anticonvulsants; Aspirin; Diazepam; Male; Mice; Pentylenetetrazole; Prostaglandins; Seizures; Valproic Acid | 2001 |
Management of rheumatic chorea: an observational study.
Topics: Anti-Dyskinesia Agents; Child; Chorea; Cross-Sectional Studies; Diazepam; Female; Haloperidol; Humans; Male; Sulpiride; Valproic Acid | 2002 |
[A case of familial paroxysmal kinesic choreoathetosis].
Topics: Anticonvulsants; Athetosis; Carbamazepine; Child; Chorea; Diazepam; Drug Therapy, Combination; Humans; Male; Pedigree; Severity of Illness Index; Valproic Acid | 2002 |
Two case studies of hypothermia induced by an increased dosage of zotepine in a combination therapy.
Topics: Adult; Anti-Anxiety Agents; Anticonvulsants; Antipsychotic Agents; Bipolar Disorder; Diazepam; Dibenzothiepins; Drug Interactions; Drug Therapy, Combination; Humans; Hypothermia; Male; Schizophrenia; Valproic Acid | 2003 |
Out-of-hospital management of benzodiazepine-resistant status epilepticus in a child with Wolf-Hirschhorn syndrome.
Topics: Abnormalities, Multiple; Anticonvulsants; Apnea; Child; Chromosome Deletion; Chromosomes, Human, Pair 4; Craniofacial Abnormalities; Diazepam; Dose-Response Relationship, Drug; Drug Therapy, Combination; Emergency Medical Services; Epilepsy, Tonic-Clonic; Female; Humans; Infusions, Intravenous; Phenobarbital; Status Epilepticus; Syndrome; Thiopental; Valproic Acid | 2003 |
Post-anoxic myoclonus: a case presentation and review of management in the rehabilitation setting.
Topics: Anticonvulsants; Clonazepam; Diazepam; Female; Heart Arrest; Humans; Hypoxia, Brain; Isoxazoles; Levetiracetam; Middle Aged; Myoclonus; Phenobarbital; Piracetam; Valproic Acid; Zonisamide | 2006 |
Effects of drugs acting on the GABA-benzodiazepine receptor complex on flurothyl-induced seizures in Mongolian gerbils.
Topics: Amino Acids; Animals; Anticonvulsants; Brain; Convulsants; Diazepam; Ethanol; Flumazenil; Flurothyl; GABA Antagonists; GABA-A Receptor Antagonists; Gerbillinae; Male; Picrotoxin; Receptors, GABA-A; Seizures; Valproic Acid | 2006 |
Transient occipitotemporal subcortical diffusion-weighted magnetic resonance imaging abnormalities associated with status epilepticus. Case report.
Topics: Adult; Carbamazepine; Diazepam; Diffusion Magnetic Resonance Imaging; Drug Administration Schedule; Electroencephalography; Humans; Injections, Intramuscular; Male; Occipital Lobe; Phenytoin; Severity of Illness Index; Status Epilepticus; Temporal Lobe; Time Factors; Valproic Acid | 2006 |
The effects of chronic valproate and diazepam in a mouse model of posttraumatic stress disorder.
Topics: Animals; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Maze Learning; Mice; Mice, Inbred ICR; Motor Activity; Stress Disorders, Post-Traumatic; Valproic Acid | 2006 |
Treatment of refractory seizures due to a benign mass present in the corpus callosum with an ion magnetic inductor: case report.
Topics: Adult; Agenesis of Corpus Callosum; Anticonvulsants; Colchicine; Combined Modality Therapy; Corpus Callosum; Diazepam; Drug Resistance; Epilepsy; Female; Humans; Ions; Lipoma; Remission Induction; Speech Disorders; Stiff-Person Syndrome; Supratentorial Neoplasms; Transcranial Magnetic Stimulation; Valproic Acid | 2005 |
Re: New lessons: classic treatments in convulsive status epilepticus.
Topics: Anticonvulsants; Benzodiazepines; Diazepam; Humans; Lorazepam; Phenytoin; Status Epilepticus; Valproic Acid | 2008 |
An adult case of cyclic vomiting syndrome successfully responding to valproic acid.
Topics: Anti-Anxiety Agents; Anticonvulsants; Antiemetics; Consciousness Disorders; Diazepam; Female; Humans; Middle Aged; Migraine Disorders; Recurrence; Sumatriptan; Syndrome; Valproic Acid; Vascular Headaches; Vasoconstrictor Agents; Vomiting | 2008 |
Status epilepticus in central nervous system infections: an experience from a developing country.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Central Nervous System Infections; Developing Countries; Diazepam; Drug Resistance; Electroencephalography; Female; Hospitals, Teaching; Humans; India; Lorazepam; Magnetic Resonance Imaging; Male; Midazolam; Middle Aged; Phenytoin; Prospective Studies; Status Epilepticus; Valproic Acid | 2008 |
[Eclampsia at a teaching hospital in Ivory Coast: management, outcome and prognostic factors].
Topics: Adolescent; Adult; Anticonvulsants; Antihypertensive Agents; Cote d'Ivoire; Diazepam; Eclampsia; Female; Humans; Phenobarbital; Pregnancy; Prognosis; Retrospective Studies; Risk Factors; Treatment Outcome; Valproic Acid | 2008 |
[Posterior reversible leukoencephalopathy in a patient with postpartum eclampsia].
Topics: Adult; Anticonvulsants; Antihypertensive Agents; Brain; Brain Edema; Cesarean Section; Diazepam; Drug Therapy, Combination; Eclampsia; Female; Humans; Hypnotics and Sedatives; Magnetic Resonance Imaging; Midazolam; Phenytoin; Posterior Leukoencephalopathy Syndrome; Postoperative Complications; Pregnancy; Puerperal Disorders; Seizures; Valproic Acid | 2008 |
Non-life-threatening leukopenia in a renal transplant recipient with acute overdose of mycophenolate mofetil.
Topics: Adult; Antidepressive Agents; Benzodiazepines; Charcoal; Cholestyramine Resin; Depressive Disorder; Diazepam; Dibenzothiazepines; Female; Humans; Immunosuppressive Agents; Kidney Transplantation; Leukopenia; Mycophenolic Acid; Quetiapine Fumarate; Renal Dialysis; Valproic Acid | 2008 |
Association of anxiolytic drugs diazepam and lorazepam, and the antiepileptic valproate, with heart defects--effects on cardiomyocytes in micromass (MM) and embryonic stem cell culture.
Topics: Animals; Anti-Anxiety Agents; Cell Line; Cell Survival; Chick Embryo; Chickens; Diazepam; Embryo, Mammalian; Embryonic Stem Cells; Heart Rate; Lorazepam; Mice; Myocardial Contraction; Myocytes, Cardiac; Proteins; Valproic Acid | 2011 |
Further characterization of the predictive validity of the Brattleboro rat model for antipsychotic efficacy.
Topics: Animals; Antipsychotic Agents; Chlorpromazine; Diazepam; Disease Models, Animal; Female; Imipramine; Inhibition, Psychological; Male; Psychotropic Drugs; Rats; Rats, Brattleboro; Reflex, Startle; Schizophrenia; Valproic Acid | 2011 |
Progressive encephalopathy with cerebral oedema and infarctions associated with valproate and diazepam overdose.
Topics: Adult; Antimanic Agents; Brain Edema; Brain Infarction; Chemical and Drug Induced Liver Injury; Coma; Diazepam; Drug Overdose; Glasgow Coma Scale; Hepatic Encephalopathy; Humans; Hypnotics and Sedatives; Male; Valproic Acid | 2011 |
Intermittent drug dosing intervals guided by the operational multiple dosing half lives for predictable plasma accumulation and fluctuation.
Topics: Administration, Oral; Antihypertensive Agents; Biological Availability; Diazepam; Dosage Forms; Drug Administration Schedule; Half-Life; Humans; Molecular Dynamics Simulation; Pharmaceutical Preparations; Pharmacokinetics; Valproic Acid | 2011 |
Electrical amygdala kindling.
Topics: Amygdala; Animals; Carbamazepine; Data Interpretation, Statistical; Diazepam; Electroencephalography; Kindling, Neurologic; Male; Rats; Rats, Wistar; Valproic Acid | 2003 |
Combined diazepam and HDAC inhibitor treatment protects against seizures and neuronal damage caused by soman exposure.
Topics: Animals; Anticonvulsants; Brain; Brain Mapping; Brain Waves; Chemical Warfare Agents; Cytoprotection; Diazepam; Drug Therapy, Combination; Electroencephalography; Histone Deacetylase Inhibitors; Hydroxamic Acids; Male; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Seizures; Soman; Time Factors; Valproic Acid; Vorinostat | 2012 |
Primary afterdischarge in organotypic hippocampal slice cultures: effects of standard antiepileptic drugs.
Topics: Action Potentials; Animals; Anticonvulsants; Diazepam; Dose-Response Relationship, Drug; Epilepsy; Hippocampus; Kindling, Neurologic; Organ Culture Techniques; Rats; Rats, Wistar; Treatment Outcome; Valproic Acid | 2012 |
A comparative electrographic analysis of the effect of sec-butyl-propylacetamide on pharmacoresistant status epilepticus.
Topics: Amides; Animals; Anticonvulsants; Cerebral Cortex; Diazepam; Dose-Response Relationship, Drug; Electroencephalography; Male; Pentobarbital; Pilocarpine; Rats; Rats, Sprague-Dawley; Status Epilepticus; Valproic Acid | 2013 |
The effect of levetiracetam on status epilepticus-induced neuronal death in the rat hippocampus.
Topics: Animals; Behavior, Animal; Cell Death; Diazepam; Disease Models, Animal; Drug Therapy, Combination; Fluoresceins; Hippocampus; Levetiracetam; Neurons; Pilocarpine; Piracetam; Rats; Rats, Sprague-Dawley; Status Epilepticus; Valproic Acid | 2013 |
[Patent rickets disclosed by loss of convulsion control in a boy with cerebral palsy].
Topics: Anticonvulsants; Calcium; Carbamazepine; Cerebral Palsy; Child, Preschool; Diazepam; Epilepsy; Humans; Hypocalcemia; Male; Microcephaly; Phenobarbital; Radiography; Rickets; Valproic Acid; Vitamin D; Vitamin D Deficiency | 2013 |
Drug screening in Scn1a zebrafish mutant identifies clemizole as a potential Dravet syndrome treatment.
Topics: Animals; Anticonvulsants; Benzimidazoles; Bromides; Diazepam; Dioxolanes; Drug Evaluation, Preclinical; Epilepsies, Myoclonic; Gene Expression Profiling; Mutation; NAV1.1 Voltage-Gated Sodium Channel; Potassium Compounds; Seizures; Valproic Acid; Voltage-Gated Sodium Channel beta-1 Subunit; Zebrafish; Zebrafish Proteins | 2013 |
Repeated seizures in an elderly patient with alcohol dependence and mild cognitive impairment.
Topics: Aged; Alcohol Withdrawal Seizures; Alcoholism; Cognitive Dysfunction; Diazepam; Humans; Male; Valproic Acid | 2013 |
Interaction of injectable neurotropic drugs with the red cell membrane.
Topics: Central Nervous System Agents; Chlorpromazine; Citalopram; Clomipramine; Clonazepam; Diazepam; Erythrocytes; Humans; Injections; Levetiracetam; Microscopy, Electron, Scanning; Neurotransmitter Agents; Phenobarbital; Phenytoin; Piracetam; Valproic Acid | 2014 |
Inter-individual variation in the effect of antiepileptic drugs in the intrahippocampal kainate model of mesial temporal lobe epilepsy in mice.
Topics: Animals; Anticonvulsants; Carbamazepine; Diazepam; Disease Models, Animal; Drug Resistance; Electrodes, Implanted; Electroencephalography; Epilepsy, Temporal Lobe; Female; Hippocampus; Kainic Acid; Levetiracetam; Mice; Phenobarbital; Phenytoin; Piracetam; Seizures; Valproic Acid | 2015 |
Cross-species pharmacological characterization of the allylglycine seizure model in mice and larval zebrafish.
Topics: Allylglycine; Animals; Anticonvulsants; Diazepam; Disease Models, Animal; Fructose; Levetiracetam; Male; Mice; Phenytoin; Piracetam; Seizures; Topiramate; Treatment Outcome; Valproic Acid; Zebrafish | 2015 |
Pediatric Herpes Simplex Virus Encephalitis Complicated by N-Methyl-D-aspartate Receptor Antibody Encephalitis.
Topics: Acyclovir; Anti-N-Methyl-D-Aspartate Receptor Encephalitis; Antiviral Agents; Autoantibodies; Clonidine; Diazepam; Encephalitis, Herpes Simplex; Encephalomalacia; Female; Fever; Humans; Immunocompromised Host; Immunosuppression Therapy; Infant; Leukoencephalopathies; Movement Disorders; Neurological Rehabilitation; Pakistan; Paresis; Phenobarbital; Phenytoin; Plasmapheresis; Receptors, N-Methyl-D-Aspartate; Seizures; Trihexyphenidyl; United Kingdom; Valproic Acid | 2015 |
Modulation of brain glutamate dehydrogenase as a tool for controlling seizures.
Topics: Animals; Anticonvulsants; Brain; Deamination; Diazepam; Disease Models, Animal; Enzyme Inhibitors; Glutamate Dehydrogenase; Glutamic Acid; Ketoglutaric Acids; Male; Mice; Oxidation-Reduction; Oxygen Consumption; Pentylenetetrazole; Phenytoin; Seizures; Time Factors; Valproic Acid | 2015 |
Evaluation of the pentylenetetrazole seizure threshold test in epileptic mice as surrogate model for drug testing against pharmacoresistant seizures.
Topics: Animals; Anticonvulsants; Diazepam; Disease Models, Animal; Drug Resistance; Epilepsy; GABA Antagonists; Levetiracetam; Male; Mice; Pentylenetetrazole; Phenobarbital; Pilocarpine; Piracetam; Rats; Seizures; Status Epilepticus; Valproic Acid | 2016 |
Pharmacological characterization of nicotine-induced tremor: Responses to anti-tremor and anti-epileptic agents.
Topics: Animals; Anticonvulsants; Antiparkinson Agents; Benzeneacetamides; Calcium Channel Blockers; Carbamazepine; Diazepam; Disease Models, Animal; Essential Tremor; Ethosuximide; Male; Mice, Inbred Strains; Nicotine; Phenobarbital; Propranolol; Pyridines; Valproic Acid | 2018 |
Pronounced antiepileptic activity of the subtype-selective GABA
Topics: Animals; Anticonvulsants; Diazepam; Dose-Response Relationship, Drug; Electrocorticography; Electrodes, Implanted; Electroencephalography; GABA Modulators; Imidazoles; Male; Pyridazines; Rats; Receptors, GABA-A; Seizures; Valproic Acid | 2019 |
Antiseizure drug efficacy and tolerability in established and novel drug discovery seizure models in outbred vs inbred mice.
Topics: Animals; Animals, Outbred Strains; Anticonvulsants; Behavior, Animal; Brain; Carbamazepine; Cornea; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Discovery; Drug Evaluation, Preclinical; Drug Resistant Epilepsy; Electroshock; Kindling, Neurologic; Lamotrigine; Levetiracetam; Locomotion; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Open Field Test; Phenobarbital; Seizures; Treatment Outcome; Valproic Acid | 2020 |
A case report on fatal intoxication by tapentadol: Study of distribution and metabolism.
Topics: Adult; Analgesics, Opioid; Benzodiazepines; Bile; Chromatography, Liquid; Diazepam; Dibenzothiazepines; Gas Chromatography-Mass Spectrometry; Gastrointestinal Contents; Hair; Humans; Male; Nordazepam; Prisoners; Tapentadol; Tranquilizing Agents; Valproic Acid | 2021 |
Management practice and discharge outcome of patients with psychiatric disorder admitted to psychiatry wards of selected specialized settings in Ethiopia.
Topics: Adult; Cross-Sectional Studies; Diazepam; Ethiopia; Hospitals, Psychiatric; Humans; Mental Disorders; Patient Discharge; Psychiatry; Risperidone; Valproic Acid | 2023 |
Utilization of Antiseizure Medications in Women of Childbearing Age With Epilepsy and Nonepilepsy Indications: A Retrospective Cohort Study.
Topics: Anticonvulsants; Clonazepam; Diazepam; Epilepsy; Female; Gabapentin; Humans; Lamotrigine; Lorazepam; Retrospective Studies; Topiramate; Valproic Acid | 2023 |