valproic acid has been researched along with deuterium in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (83.33) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hoffmann, F; Jancik, BC; von Unruh, GE | 1 |
| Baillie, TA; Boberg, M; Rettenmeier, AW; Rettie, AE | 1 |
| Hoffman, DJ; Porter, WR | 1 |
| Abbott, F; Acheampong, A; Burton, R | 1 |
| Abbott, FS; Acheampong, AA; Burton, RW; Ferguson, SM; Orr, JM | 1 |
| Baillie, TA; Gonzalez, FJ; Korzekwa, KR; Philpot, RM; Rettie, AE; Sheffels, PR | 1 |
6 other study(ies) available for valproic acid and deuterium
| Article | Year |
|---|---|
[Bioavailability of a valproic acid preparation. The relative bioavailability of enteric-resistant valproic acid preparations in tablet form with simultaneously administered tetradeuterated valproic acid as the bioavailability reference].
Topics: Adult; Biological Availability; Deuterium; Female; Humans; Kinetics; Male; Tablets, Enteric-Coated; Valproic Acid | 1986 |
Cytochrome P-450-catalyzed desaturation of valproic acid in vitro. Species differences, induction effects, and mechanistic studies.
Topics: Animals; Carbamazepine; Cytochrome P-450 Enzyme System; Deuterium; Enzyme Induction; Fatty Acids, Monounsaturated; Female; Gas Chromatography-Mass Spectrometry; Humans; Hydroxylation; Male; Mice; Mice, Inbred BALB C; Microsomes, Liver; Phenobarbital; Phenytoin; Rabbits; Rats; Rats, Inbred Strains; Species Specificity; Valproic Acid | 1988 |
Resolution of valproic acid from deuterated analogues and their quantitation in plasma using capillary gas chromatography.
Topics: Animals; Biotransformation; Chromatography, Gas; Deuterium; Dogs; Valproic Acid | 1983 |
Identification of valproic acid metabolites in human serum and urine using hexadeuterated valproic acid and gas chromatographic mass spectrometric analysis.
Topics: Biotransformation; Deuterium; Gas Chromatography-Mass Spectrometry; Humans; Magnetic Resonance Spectroscopy; Male; Valproic Acid | 1983 |
Use of hexadeuterated valproic acid and gas chromatography-mass spectrometry to determine the pharmacokinetics of valproic acid.
Topics: Adult; Blood Proteins; Deuterium; Gas Chromatography-Mass Spectrometry; Humans; Isotope Labeling; Kinetics; Male; Protein Binding; Saliva; Time Factors; Valproic Acid | 1984 |
CYP4 isozyme specificity and the relationship between omega-hydroxylation and terminal desaturation of valproic acid.
Topics: Animals; Cytochrome P-450 Enzyme System; Deuterium; Fatty Acids, Monounsaturated; Female; Hydroxylation; Isoenzymes; Lung; Male; Microsomes; Oxidoreductases; Rabbits; Substrate Specificity; Valproic Acid | 1995 |