valproic acid and dacarbazine

valproic acid has been researched along with dacarbazine in 38 studies

Research

Studies (38)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	7 (18.42)	29.6817
2010's	30 (78.95)	24.3611
2020's	1 (2.63)	2.80

Authors

Authors	Studies
Lombardo, F; Obach, RS; Waters, NJ	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y	1
Dellinger, CA; Grewal, J; Yung, WK	1
Akagi, T; Aoyanagi, E; Kaneko, S; Sasai, K; Tabu, K; Tanaka, S	1
Ballarini, M; Contegno, F; Croci, D; Goldhirsch, A; Minucci, S; Munzone, E; Nolè, F; Pelicci, PG; Rocca, A; Salmaggi, A; Testori, A; Tosti, G	1
Hoorens, A; Neyns, B; Stupp, R	1
Chang, YJ; Chen, CH; Chung, KT; Ku, MS; Yang, JT	1
Belohlavek, C; Fritz, G; Jöst, E; Kaina, B; Nagel, G; Roos, WP	1
Belanger, K; Bogdahn, U; Brandes, AA; Cairncross, JG; Forsyth, P; Gorlia, T; Lacombe, D; Macdonald, DR; Mason, W; Mirimanoff, RO; Rossetti, AO; Stupp, R; van den Bent, MJ; Vecht, CJ; Weller, M	1
Lafleur, MV; Slotman, BJ; Sminia, P; Stalpers, LJ; Van den Berg, J; Van Nifterik, KA	1
Hou, Y; Jeong, CH; Jeun, SS; Kim, SM; Lim, JY; Park, KY; Ryu, CH; Woo, JS; Yoon, WS	1
Chen, FR; Chen, ZP; Li, C; Shao, CJ; Wu, MW; Xia, YF	1
Barker, CA; Beal, K; Bishop, AJ; Chan, TA; Chang, M	1
Dielemans, JC; Kerkhof, M; Taphoorn, MJ; van Breemen, MS; Vecht, CJ; Walchenbach, R; Zwinkels, H	1
Airenne, K; Alasaarela, L; Määttä, AM; Pikkarainen, J; Samaranayake, H; Stedt, H; Ylä-Herttuala, S	1
Buslei, R; Derer, A; Fietkau, R; Frey, B; Gaipl, US; Muth, C; Rubner, Y; Sieber, R; Strnad, A	1
Cosgrove, L; Day, B; Fay, M; Head, R; Hosein, AN; Lim, YC; Martin, JH; Rose, S; Sminia, P; Stringer, B	1
Annovazzi, L; Biunno, I; Cassoni, P; Cattaneo, M; De Blasio, P; Melcarne, A; Mellai, M; Schiffer, D; Storaci, AM	1
Camphausen, K; Chang, MG; Fine, HA; Holdford, DJ; Krauze, AV; Myrehaug, SD; Shih, J; Smith, S; Tofilon, PJ	1
Chinot, O; Cloughesy, T; Gilbert, MR; Gorlia, T; Happold, C; Hegi, M; Mehta, MP; Nabors, LB; Perry, JR; Pugh, SL; Reardon, DA; Roth, P; Stupp, R; Weller, M; Wick, W	1
Dietrich, J; Le, A; McDonnell, E; Nahed, BV; Redjal, N; Reinshagen, C; Walcott, BP	1
Bumes, E; Eyüpoglu, IY; Hau, P; Hutterer, M; Proske, J; Savaskan, NE; Seliger, C; Uhl, M; Vollmann-Zwerenz, A; Walter, L	1
Pellerino, A; Rudà, R; Soffietti, R	1
Baronchelli, S; Bentivegna, A; Butta, V; Cilibrasi, C; Dalprà, L; Lavitrano, M; Redaelli, S; Riva, G	1
Cosgrove, L; Dowson, N; Fay, MF; Head, R; Martin, JH; Rose, SE; Sminia, P	1
Hau, P; Herold-Mende, C; Hoja, S; Proescholdt, M; Rehli, M; Riemenschneider, MJ; Schulze, M	1
Araki, H; Kuwabara, Y; Ohue, S; Suehiro, S; Tanaka, A; Tanaka, M; Watanabe, S; Yamashita, D	1
Cruz, R; Figg, WD; League-Pascual, JC; Lester-McCully, CM; Peer, CJ; Rodgers, L; Ronner, L; Shandilya, S; Warren, KE	1
Barszczewska-Pietraszek, G; Czarny, P; Czyż, M; Drzewiecka, M; Gajos-Michniewicz, A; Hoser, G; Jaśniak, D; Piekarski, J; Radek, M; Sitarek, P; Skorski, T; Śliwiński, T	1

Reviews

1 review(s) available for valproic acid and dacarbazine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

3 trial(s) available for valproic acid and dacarbazine

Article	Year
A phase I-II study of the histone deacetylase inhibitor valproic acid plus chemoimmunotherapy in patients with advanced melanoma. British journal of cancer, 2009, Jan-13, Volume: 100, Issue:1 Topics: Adult; Aged; Dacarbazine; Enzyme Inhibitors; Female; Histone Deacetylase Inhibitors; Humans; Interferon-alpha; Male; Melanoma; Middle Aged; Valproic Acid	2009
Prolonged survival with valproic acid use in the EORTC/NCIC temozolomide trial for glioblastoma. Neurology, 2011, Sep-20, Volume: 77, Issue:12 Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Canada; Dacarbazine; Europe; Female; Glioblastoma; Humans; Male; Middle Aged; Retrospective Studies; Survival Rate; Temozolomide; Valproic Acid; Young Adult	2011
A Phase 2 Study of Concurrent Radiation Therapy, Temozolomide, and the Histone Deacetylase Inhibitor Valproic Acid for Patients With Glioblastoma. International journal of radiation oncology, biology, physics, 2015, Aug-01, Volume: 92, Issue:5 Topics: Adult; Age Factors; Aged; Antineoplastic Agents, Alkylating; Bone Marrow; Brain Neoplasms; Chemoradiotherapy; Chemotherapy, Adjuvant; Dacarbazine; Disease Progression; Disease-Free Survival; Drug Administration Schedule; Female; Glioblastoma; Histone Deacetylase Inhibitors; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Multivariate Analysis; Radiation Tolerance; Radiation-Sensitizing Agents; Temozolomide; Time Factors; Valproic Acid	2015

Other Studies

34 other study(ies) available for valproic acid and dacarbazine

Article	Year
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships. Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16 Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone	2016
Fatal reactivation of hepatitis B with temozolomide. The New England journal of medicine, 2007, Apr-12, Volume: 356, Issue:15 Topics: Aged; Anticonvulsants; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Fatal Outcome; Female; Glioblastoma; Hepatitis B; Hepatitis B virus; Humans; Temozolomide; Temporal Lobe; Valproic Acid; Viral Load; Virus Activation	2007
O6-methylguanine-DNA methyltransferase is downregulated in transformed astrocyte cells: implications for anti-glioma therapies. Molecular cancer, 2007, Jun-05, Volume: 6 Topics: 3T3 Cells; Animals; Antineoplastic Agents; Astrocytes; Cell Division; Dacarbazine; DNA Modification Methylases; DNA Repair Enzymes; Glioma; Humans; Mice; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Temozolomide; Transfection; Transplantation, Heterologous; Tumor Suppressor Proteins; Valproic Acid	2007
Valproic acid related idiosyncratic drug induced hepatotoxicity in a glioblastoma patient treated with temozolomide. Acta neurologica Belgica, 2008, Volume: 108, Issue:4 Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemical and Drug Induced Liver Injury; Chemotherapy, Adjuvant; Cholestasis; Dacarbazine; Glioblastoma; Humans; Liver Failure; Male; Middle Aged; Temozolomide; Valproic Acid	2008
Enhancement of temozolomide-induced apoptosis by valproic acid in human glioma cell lines through redox regulation. Journal of molecular medicine (Berlin, Germany), 2011, Volume: 89, Issue:3 Topics: Antineoplastic Agents, Alkylating; Apoptosis; Cell Line, Tumor; Dacarbazine; Drug Synergism; Glioma; Humans; Oxidation-Reduction; Temozolomide; Valproic Acid	2011
Intrinsic anticancer drug resistance of malignant melanoma cells is abrogated by IFN-β and valproic acid. Cancer research, 2011, Jun-15, Volume: 71, Issue:12 Topics: Animals; Antineoplastic Agents; Apoptosis; Caspase 8; Cell Line, Tumor; Dacarbazine; DNA Breaks, Double-Stranded; DNA Mismatch Repair; DNA Modification Methylases; DNA Repair Enzymes; Drug Resistance, Neoplasm; Female; Humans; Interferon-beta; Male; Melanoma; Mice; Temozolomide; Tumor Suppressor Proteins; Valproic Acid	2011
Valproic acid sensitizes human glioma cells for temozolomide and γ-radiation. Journal of neuro-oncology, 2012, Volume: 107, Issue:1 Topics: Anticonvulsants; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Proliferation; Dacarbazine; Gamma Rays; Glioma; Humans; Radiation Tolerance; Radiation-Sensitizing Agents; Temozolomide; Tumor Cells, Cultured; Tumor Stem Cell Assay; Valproic Acid	2012
Valproic acid downregulates the expression of MGMT and sensitizes temozolomide-resistant glioma cells. Journal of biomedicine & biotechnology, 2012, Volume: 2012 Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; DNA Modification Methylases; DNA Repair Enzymes; Down-Regulation; Drug Resistance, Neoplasm; Drug Synergism; Gene Expression Regulation, Neoplastic; Glioma; Humans; Mice; Temozolomide; Tumor Suppressor Proteins; Valproic Acid; Xenograft Model Antitumor Assays	2012
Histone deacetylase inhibitor, 2-propylpentanoic acid, increases the chemosensitivity and radiosensitivity of human glioma cell lines in vitro. Chinese medical journal, 2012, Volume: 125, Issue:24 Topics: Apoptosis; Blotting, Western; Cell Line, Tumor; Cell Survival; Dacarbazine; Flow Cytometry; Glioma; Histone Deacetylase Inhibitors; Humans; Temozolomide; Valproic Acid	2012
Valproic acid use during radiation therapy for glioblastoma associated with improved survival. International journal of radiation oncology, biology, physics, 2013, Jul-01, Volume: 86, Issue:3 Topics: Adolescent; Adult; Aged; Anticonvulsants; Antineoplastic Agents, Alkylating; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Female; Glioblastoma; Histone Deacetylase Inhibitors; Humans; Male; Middle Aged; Multivariate Analysis; Retrospective Studies; Seizures; Survival Analysis; Temozolomide; Treatment Outcome; Valproic Acid; Young Adult	2013
Effect of valproic acid on seizure control and on survival in patients with glioblastoma multiforme. Neuro-oncology, 2013, Volume: 15, Issue:7 Topics: Adult; Aged; Aged, 80 and over; Anticonvulsants; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Drug Therapy, Combination; Female; Follow-Up Studies; Glioblastoma; Humans; Levetiracetam; Male; Middle Aged; Neoplasm Recurrence, Local; Piracetam; Prognosis; Retrospective Studies; Seizures; Survival Rate; Temozolomide; Valproic Acid; Young Adult	2013
Improved therapeutic effect on malignant glioma with adenoviral suicide gene therapy combined with temozolomide. Gene therapy, 2013, Volume: 20, Issue:12 Topics: Adenoviruses, Human; Animals; Antineoplastic Agents, Alkylating; Antiviral Agents; Combined Modality Therapy; Dacarbazine; Ganciclovir; Genes, Transgenic, Suicide; Genes, Viral; Genetic Therapy; Genetic Vectors; Glioma; Herpesvirus 1, Human; Humans; Male; Neoplasms, Experimental; Rats; Temozolomide; Thymidine Kinase; Treatment Outcome; Tumor Cells, Cultured; Valproic Acid	2013
Fractionated radiotherapy is the main stimulus for the induction of cell death and of Hsp70 release of p53 mutated glioblastoma cell lines. Radiation oncology (London, England), 2014, Mar-30, Volume: 9, Issue:1 Topics: Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Cycle; Cell Death; Cell Line, Tumor; Dacarbazine; Dose Fractionation, Radiation; G2 Phase; Glioblastoma; HMGB1 Protein; HSP70 Heat-Shock Proteins; Humans; Mutation; Necrosis; Temozolomide; Tumor Suppressor Protein p53; Valproic Acid	2014
The effect of valproic acid in combination with irradiation and temozolomide on primary human glioblastoma cells. Journal of neuro-oncology, 2015, Volume: 122, Issue:2 Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Survival; Cells, Cultured; Chemoradiotherapy; Dacarbazine; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Dose-Response Relationship, Drug; Gene Expression Profiling; Glioblastoma; Humans; Mice, Inbred NOD; Mice, SCID; Microarray Analysis; Neoplasm Transplantation; Promoter Regions, Genetic; Radiation-Sensitizing Agents; Temozolomide; Tumor Suppressor Proteins; Valproic Acid	2015
SEL1L SNP rs12435998, a predictor of glioblastoma survival and response to radio-chemotherapy. Oncotarget, 2015, May-20, Volume: 6, Issue:14 Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Blotting, Western; Brain Neoplasms; Cell Line, Tumor; Chemoradiotherapy; Dacarbazine; Doxorubicin; Genotype; Glioblastoma; Humans; Kaplan-Meier Estimate; Paclitaxel; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Proteins; Temozolomide; Valproic Acid	2015
Does Valproic Acid or Levetiracetam Improve Survival in Glioblastoma? A Pooled Analysis of Prospective Clinical Trials in Newly Diagnosed Glioblastoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016, Mar-01, Volume: 34, Issue:7 Topics: Adolescent; Adult; Aged; Anticonvulsants; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Clinical Trials as Topic; Dacarbazine; Epilepsy; Female; Glioblastoma; Humans; Levetiracetam; Male; Middle Aged; Piracetam; Prognosis; Survival Analysis; Temozolomide; Valproic Acid	2016
Valproic acid, compared to other antiepileptic drugs, is associated with improved overall and progression-free survival in glioblastoma but worse outcome in grade II/III gliomas treated with temozolomide. Journal of neuro-oncology, 2016, Volume: 127, Issue:3 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Dacarbazine; Drug Therapy, Combination; Female; Follow-Up Studies; Glioblastoma; Humans; Male; Middle Aged; Neoplasm Grading; Neoplasm Recurrence, Local; Prognosis; Retrospective Studies; Survival Rate; Temozolomide; Valproic Acid; Young Adult	2016
Adaptive Immune Response to and Survival Effect of Temozolomide- and Valproic Acid-induced Autophagy in Glioblastoma. Anticancer research, 2016, Volume: 36, Issue:3 Topics: Adaptive Immunity; Animals; Antineoplastic Combined Chemotherapy Protocols; Autophagy; Brain Neoplasms; Cancer Vaccines; Cell Line, Tumor; Dacarbazine; Glioblastoma; Mice; Retrospective Studies; Survival Analysis; Temozolomide; Treatment Outcome; Valproic Acid; Xenograft Model Antitumor Assays	2016
Does valproic acid affect tumor growth and improve survival in glioblastomas? CNS oncology, 2016, Volume: 5, Issue:2 Topics: Anticonvulsants; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Differentiation; Cell Proliferation; Combined Modality Therapy; Dacarbazine; Glioblastoma; Histone Deacetylase Inhibitors; Humans; Seizures; Temozolomide; Valproic Acid	2016
Epigenetic targeting of glioma stem cells: Short-term and long-term treatments with valproic acid modulate DNA methylation and differentiation behavior, but not temozolomide sensitivity. Oncology reports, 2016, Volume: 35, Issue:5 Topics: Antineoplastic Agents, Alkylating; Cell Line, Tumor; Cell Shape; Cell Survival; Cell Transformation, Neoplastic; Dacarbazine; DNA Methylation; Drug Resistance, Neoplasm; Drug Synergism; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Glioblastoma; Histone Deacetylase Inhibitors; Humans; Neoplastic Stem Cells; Promoter Regions, Genetic; Temozolomide; Valproic Acid	2016
Valproate in Adjuvant Glioblastoma Treatment. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016, 09-01, Volume: 34, Issue:25 Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Dacarbazine; Glioblastoma; Humans; Treatment Outcome; Valproic Acid	2016
Molecular dissection of the valproic acid effects on glioma cells. Oncotarget, 2016, Sep-27, Volume: 7, Issue:39 Topics: Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Chromatin; Dacarbazine; Decision Support Systems, Clinical; DNA Repair; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Glioblastoma; Glioma; High-Throughput Nucleotide Sequencing; Histone Deacetylase Inhibitors; Histones; Humans; RNA; RNA, Small Interfering; Temozolomide; Transcription, Genetic; Treatment Outcome; Valproic Acid	2016
Valproic acid reduces hair loss and improves survival in patients receiving temozolomide-based radiation therapy for high-grade glioma. European journal of clinical pharmacology, 2017, Volume: 73, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Alopecia; Antineoplastic Agents, Alkylating; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Female; Glioma; Histone Deacetylase Inhibitors; Humans; Male; Middle Aged; Temozolomide; Valproic Acid; Young Adult	2017
Plasma and cerebrospinal fluid pharmacokinetics of select chemotherapeutic agents following intranasal delivery in a non-human primate model. Journal of neuro-oncology, 2017, Volume: 132, Issue:3 Topics: Administration, Intranasal; Animals; Antineoplastic Agents; Blood-Brain Barrier; Dacarbazine; Disease Models, Animal; Macaca mulatta; Male; Nasal Absorption; Phosphorylcholine; Temozolomide; Valproic Acid	2017
Histone Deacetylases (HDAC) Inhibitor-Valproic Acid Sensitizes Human Melanoma Cells to Dacarbazine and PARP Inhibitor. Genes, 2023, 06-20, Volume: 14, Issue:6 Topics: Alkylating Agents; Antineoplastic Agents; Dacarbazine; DNA; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Melanoma; Poly(ADP-ribose) Polymerase Inhibitors; Valproic Acid	2023