valproic acid has been researched along with d-alpha tocopherol in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (13.64) | 18.7374 |
| 1990's | 2 (9.09) | 18.2507 |
| 2000's | 9 (40.91) | 29.6817 |
| 2010's | 6 (27.27) | 24.3611 |
| 2020's | 2 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Strassburg, CP; Tukey, RH | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Jankowicz, E; Kułak, W; Rudziński, P; Sobaniec, W; Sobaniec-Lotowska, M | 1 |
| Kryzhanovskiĭ, GN; Shandra, AA | 1 |
| Buchi, KN; Gray, PD; Rollins, DE; Tolman, KG | 1 |
| De Caro, V; Di Stefano, V; Giannola, LI; Rizzo, MC | 1 |
| Abbott, FS; Huang, HS; Jurima-Romet, M; Tang, W; Whitehouse, LW | 1 |
| Al Deeb, S; Al Moutaery, K; Arshaduddin, M; Tariq, M | 1 |
| Bhattacharya, D; Bhattacharya, SK; Ghosal, S; Sairam, K | 1 |
| Bhattachary, SK; Bhattacharya, D; Muruganandam, AV | 1 |
| Hescheler, J; Na, L; Nau, H; Sauer, H; Wartenberg, M | 1 |
| Chiarelli, F; De Simone, M; Greco, R; Latini, G; Verrotti, A | 1 |
| Akkus, M; Baran, OP; Kervancioglu, P; Nergiz, Y | 1 |
| Baran, O; Nergiz, Y; Tuncer, MC | 1 |
| Chiarelli, F; Franzoni, E; Manco, R; Scardapane, A; Verrotti, A | 1 |
| Chen, KC; Hsieh, CL; Lin, PX; Peng, CC; Peng, RY | 1 |
| Chen, Y; Hsieh, CL; Lin, PX; Peng, CC; Peng, RY | 1 |
| Baldisserotto, B; Barreto, KP; Glanzner, WG; Gonçalves, PB; Ourique, GM; Pavanato, MA; Pês, TS; Saccol, EM; Schiefelbein, SH; Woehl, VM | 1 |
| Gluzman, DF; Kravchuk, IV; Shvachko, LP; Telegeev, GD; Zavelevich, MP | 1 |
| Conei, D; Risopatrón, J; Rojas, M; Santamaría, L | 1 |
| Ahmed, MM; Alsemeh, AE; Fawzy, A; Rezq, S; Samy, W; Tharwat, M | 1 |
2 review(s) available for valproic acid and d-alpha tocopherol
| Article | Year |
|---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic | 2000 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
1 trial(s) available for valproic acid and d-alpha tocopherol
| Article | Year |
|---|---|
Obesity and plasma concentrations of alpha-tocopherol and beta-carotene in epileptic girls treated with valproate.
Topics: Adolescent; alpha-Tocopherol; Anticonvulsants; Antioxidants; beta Carotene; Body Weight; Carotenoids; Child; Epilepsy; Female; Follow-Up Studies; Humans; Obesity; Prospective Studies; Valproic Acid; Weight Gain | 2004 |
19 other study(ies) available for valproic acid and d-alpha tocopherol
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Cardiazol-induced seizures and the concentration of lipid peroxides in the brain of rats under the influence of valproic acid and vitamin E.
Topics: Animals; Anticonvulsants; Antioxidants; Cerebral Cortex; Convulsants; Drug Therapy, Combination; Epilepsy; Hippocampus; Lipid Peroxides; Male; Pentylenetetrazole; Rats; Rats, Inbred Strains; Valproic Acid; Vitamin E | 1989 |
[Effect of diazepam, carbamazepine, sodium valproate and their combinations with vitamin preparations on epileptic activity].
Topics: Animals; Anticonvulsants; Carbamazepine; Diazepam; Drug Therapy, Combination; Male; Niacinamide; Pentylenetetrazole; Pyridoxal Phosphate; Rats; Seizures; Valproic Acid; Vitamin E; Vitamins | 1985 |
Protection against sodium valproate injury in isolated hepatocytes by alpha-tocopherol and N,N'-diphenyl-p-phenylenediamine.
Topics: Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Glucuronates; Lipid Peroxides; Liver; Male; Phenylenediamines; Rats; Rats, Inbred Strains; Valproic Acid; Vitamin E | 1984 |
In vitro evaluation of cumulative release of valproic acid and vitamin E from hexadecanol microspheres. Part 2: Antiepileptic agents.
Topics: Aldehydes; Anticonvulsants; Delayed-Action Preparations; Kinetics; Microspheres; Models, Biological; Particle Size; Valproic Acid; Vitamin E | 1993 |
Cytotoxicity of unsaturated metabolites of valproic acid and protection by vitamins C and E in glutathione-depleted rat hepatocytes.
Topics: Analysis of Variance; Animals; Anticonvulsants; Ascorbic Acid; Cells, Cultured; Chromatography, Liquid; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Induction; Enzyme Inhibitors; Glutathione; Homeostasis; L-Lactate Dehydrogenase; Liver; Male; Mass Spectrometry; Methionine; Phenobarbital; Pregnenolone Carbonitrile; Rats; Rats, Inbred F344; Valproic Acid; Vitamin E | 1996 |
Vitamin E decreases valproic acid induced neural tube defects in mice.
Topics: Administration, Oral; Animals; Crown-Rump Length; Dose-Response Relationship, Drug; Female; Fetal Weight; Fetus; Mice; Mice, Inbred BALB C; Neural Tube Defects; Pregnancy; Teratogens; Valproic Acid; Vitamin E | 2000 |
Effect of Withania somnifera glycowithanolides on a rat model of tardive dyskinesia.
Topics: Animals; Anti-Dyskinesia Agents; Anticonvulsants; Antioxidants; Disease Models, Animal; Dyskinesia, Drug-Induced; Ergosterol; Glycosides; Haloperidol; Male; Phytotherapy; Plant Extracts; Plant Roots; Rats; Rats, Wistar; Sitosterols; Solanaceae; Valproic Acid; Vitamin E; Withanolides | 2002 |
Effect of Emblica officinalis tannoids on a rat model of tardive dyskinesia.
Topics: Animals; Anti-Dyskinesia Agents; Anticonvulsants; Antioxidants; Brain; Disease Models, Animal; Dyskinesia, Drug-Induced; Euphorbiaceae; GABA Modulators; Haloperidol; Male; Phytotherapy; Plant Extracts; Plant Roots; Rats; Rats, Wistar; Tannins; Valproic Acid; Vitamin E | 2000 |
Anticonvulsant valproic acid inhibits cardiomyocyte differentiation of embryonic stem cells by increasing intracellular levels of reactive oxygen species.
Topics: Actins; Animals; Anticonvulsants; Cell Differentiation; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Drug Combinations; Free Radical Scavengers; Immunohistochemistry; Mice; Myocytes, Cardiac; Organoids; Reactive Oxygen Species; Sarcomeres; Stem Cells; Valproic Acid; Vitamin E | 2003 |
Ultrastructural investigation of the protective role of folic acid and vitamin E against toxic effects of valproic acid on maternal liver tissue during period of gestation.
Topics: Animals; Anticonvulsants; Chemical and Drug Induced Liver Injury; Female; Folic Acid; Injections, Subcutaneous; Liver; Pregnancy; Rats; Rats, Wistar; Valproic Acid; Vitamin E; Vitamins | 2006 |
The effects of valproic acid, vitamin E and folic acid on ribs of rat fetuses in the prenatal period.
Topics: Animals; Bone and Bones; Female; Fetal Development; Folic Acid; Models, Animal; Pregnancy; Rats; Rats, Wistar; Ribs; Teratogens; Valproic Acid; Vitamin E | 2006 |
Increased oxidative stress in epileptic children treated with valproic acid.
Topics: Anthropometry; Anticonvulsants; Antioxidants; Blood Chemical Analysis; Blood Glucose; Child; Epilepsy, Generalized; Female; Humans; Insulin; Lipid Peroxidation; Lipoproteins, LDL; Male; Malondialdehyde; Obesity; Oxidative Stress; Prospective Studies; Valproic Acid; Vitamin E | 2008 |
Resveratrol and vitamin E rescue valproic acid-induced teratogenicity: the mechanism of action.
Topics: Abnormalities, Drug-Induced; Animals; Antioxidants; Chick Embryo; Glutathione; Reactive Oxygen Species; Resveratrol; Stilbenes; Teratogenesis; Valproic Acid; Vitamin E | 2014 |
The proteomic and genomic teratogenicity elicited by valproic acid is preventable with resveratrol and α-tocopherol.
Topics: alpha-Tocopherol; Animals; Anticonvulsants; Betaine-Homocysteine S-Methyltransferase; Carrier Proteins; Chick Embryo; Chromatography, Liquid; Filamins; Gene Expression Regulation; Membrane Proteins; Myosin Light Chains; Phosphatidylethanolamine Binding Protein; Proteome; Resveratrol; Serum Albumin; Stilbenes; Tandem Mass Spectrometry; Teratogens; Thyroid Hormone-Binding Proteins; Thyroid Hormones; Valproic Acid | 2014 |
Protective effect of vitamin E on sperm motility and oxidative stress in valproic acid treated rats.
Topics: Animals; Anticonvulsants; Antioxidants; Biological Assay; Epididymis; Glutathione; Lipid Peroxidation; Male; Oxidative Stress; Protective Agents; Rats; Rats, Wistar; Sperm Count; Sperm Motility; Spermatogenesis; Testis; Testosterone; Valproic Acid; Vitamin E | 2016 |
Vitamin Е activates expression of С/EBP alpha transcription factor and G-CSF receptor in leukemic K562 cells.
Topics: Antineoplastic Agents; CCAAT-Enhancer-Binding Protein-alpha; Cell Line, Tumor; Fusion Proteins, bcr-abl; Gene Expression Regulation, Leukemic; Humans; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Receptors, Granulocyte Colony-Stimulating Factor; Transcriptional Activation; Valproic Acid; Vitamin E | 2018 |
Protective role of vitamin E in testicular development of mice exposed to valproic acid.
Topics: Animals; Anticonvulsants; Female; Male; Mice; Oxidative Stress; Pregnancy; Testis; Valproic Acid; Vitamin E | 2021 |
Vitamin E rescues valproic acid-induced testicular injury in rats: Role of autophagy.
Topics: AMP-Activated Protein Kinases; Animals; Autophagy; Beclin-1; Catalase; Gene Expression Regulation; Male; Malondialdehyde; Microtubule-Associated Proteins; Rats; Sperm Motility; Superoxide Dismutase; Testis; Testosterone; TOR Serine-Threonine Kinases; Valproic Acid; Vitamin E | 2022 |