valproic acid has been researched along with cyclin d1 in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (45.45) | 29.6817 |
| 2010's | 6 (54.55) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bacon, CL; Gallagher, HC; Haughey, JC; Regan, CM | 1 |
| Desmond, JC; Gui, D; Koeffler, HP; Kumagai, T; Miyakawa, I; Said, JW; Takai, N; Whittaker, S | 1 |
| Koistinen, P; Savolainen, ER; Siitonen, T | 1 |
| Chen, H; Greenblatt, DY; Haymart, M; Jaskula-Sztul, R; Kunnimalaiyaan, M; Ning, L; Vaccaro, AM | 1 |
| Zhang, ZH; Zhao, L; Zhu, CM | 1 |
| Huang, K; Li, Y; Ma, L; Nie, D; Wang, X; Wu, Y; Xiao, J; Xie, S; Yin, S | 1 |
| Baek, SS; Ji, ES; Kim, CJ; Kim, JE; Lee, SJ; Park, JK; Seo, TB; Shin, MS | 1 |
| Boku, S; Inoue, T; Kato, A; Kitaichi, Y; Kusumi, I; Masuda, T; Nakagawa, S; Nishikawa, H; Omiya, Y; Takamura, N | 1 |
| Bagci, G; Dodurga, Y; Gundogdu, G; Koc, T; Kucukatay, V; Satiroglu-Tufan, NL; Tekin, V | 1 |
| Chai, YG; Cho, GW; Choi, MR; Han, DM; Jeong, SG; Jung, KH | 1 |
| Gu, WP; Ma, XJ; Wang, YS; Zhao, X | 1 |
11 other study(ies) available for valproic acid and cyclin d1
| Article | Year |
|---|---|
Antiproliferative action of valproate is associated with aberrant expression and nuclear translocation of cyclin D3 during the C6 glioma G1 phase.
Topics: Active Transport, Cell Nucleus; Animals; Anticonvulsants; Cell Cycle; Cell Cycle Proteins; Cell Division; Cell Line; Cell Nucleus; Cyclin D1; Cyclin D3; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Cyclins; Dose-Response Relationship, Drug; G1 Phase; Glioma; Immunoblotting; Immunohistochemistry; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins; Rats; Tumor Suppressor Proteins; Valproic Acid | 2002 |
Histone deacetylase inhibitors have a profound antigrowth activity in endometrial cancer cells.
Topics: Agar; Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Cadherins; Cell Cycle Proteins; Cell Division; Cell Line, Tumor; Chromatin; Cyclin D1; Cyclin D2; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclins; Dose-Response Relationship, Drug; Endometrial Neoplasms; Enzyme Inhibitors; Female; Flow Cytometry; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; In Situ Nick-End Labeling; Mice; Mice, Nude; Precipitin Tests; Proto-Oncogene Proteins c-bcl-2; S Phase; Sodium Oxybate; Time Factors; Tumor Suppressor Proteins; Valproic Acid; Vorinostat | 2004 |
Increase in Ara-C cytotoxicity in the presence of valproate, a histone deacetylase inhibitor, is associated with the concurrent expression of cyclin D1 and p27(Kip 1) in acute myeloblastic leukemia cells.
Topics: Butyrates; Cell Cycle; Cell Death; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p27; Cytarabine; Enzyme Inhibitors; Etoposide; Histone Deacetylase Inhibitors; Humans; Leukemia, Myeloid, Acute; Valproic Acid | 2005 |
Valproic acid activates notch-1 signaling and regulates the neuroendocrine phenotype in carcinoid cancer cells.
Topics: Animals; Antineoplastic Agents; Carcinoid Tumor; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Chromogranin A; Cyclin D1; Gastrointestinal Neoplasms; Genes, Reporter; Humans; Luciferases; Lung Neoplasms; Male; Mice; Mice, Nude; Phenotype; Receptor, Notch1; RNA Interference; Signal Transduction; Valproic Acid; Xenograft Model Antitumor Assays | 2007 |
[Inhibitory effect of valproic acid on cell cycle of Kasumi-1 cell line and its mechanism].
Topics: Cell Cycle; Cell Line, Tumor; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p21; Histone Deacetylase Inhibitors; Humans; RNA, Messenger; Valproic Acid | 2008 |
Synergistic/additive interaction of valproic acid with bortezomib on proliferation and apoptosis of acute myeloid leukemia cells.
Topics: Acute Disease; Apoptosis; Blotting, Western; Boronic Acids; Bortezomib; Cell Proliferation; Cell Survival; Cyclin D1; Drug Synergism; Gene Expression; Histone Deacetylase Inhibitors; HL-60 Cells; Humans; Inhibitory Concentration 50; Leukemia, Myeloid; Proteasome Inhibitors; Pyrazines; Reverse Transcriptase Polymerase Chain Reaction; Telomerase; Valproic Acid | 2012 |
Treadmill exercise ameliorates motor disturbance through inhibition of apoptosis in the cerebellum of valproic acid-induced autistic rat pups.
Topics: Animals; Animals, Newborn; Apoptosis; Autistic Disorder; bcl-2-Associated X Protein; Caspase 3; Cell Adhesion Molecules, Neuronal; Cerebellum; Cyclin D1; Extracellular Matrix Proteins; Glutamate Decarboxylase; Male; Nerve Tissue Proteins; Physical Conditioning, Animal; Proto-Oncogene Proteins c-bcl-2; Psychomotor Performance; Rats; Reelin Protein; Serine Endopeptidases; Valproic Acid | 2013 |
Valproate recovers the inhibitory effect of dexamethasone on the proliferation of the adult dentate gyrus-derived neural precursor cells via GSK-3β and β-catenin pathway.
Topics: Animals; Antimanic Agents; beta Catenin; Cell Proliferation; Cyclin D1; Dentate Gyrus; Dexamethasone; Glucocorticoids; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Histone Deacetylase Inhibitors; Histone Deacetylases; Male; Neural Stem Cells; Phosphorylation; Rats; Rats, Sprague-Dawley; RNA, Messenger; Valproic Acid | 2014 |
Valproic acid inhibits the proliferation of SHSY5Y neuroblastoma cancer cells by downregulating URG4/URGCP and CCND1 gene expression.
Topics: Antineoplastic Agents; Apoptosis Regulatory Proteins; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclin D1; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Proteins; Neurons; Signal Transduction; Transcription Factor RelA; Valproic Acid | 2014 |
Proteomic analysis reveals KRIT1 as a modulator for the antioxidant effects of valproic acid in human bone-marrow mesenchymal stromal cells.
Topics: Antioxidants; Blotting, Western; Bone Marrow Cells; Cells, Cultured; Cyclin D1; Dose-Response Relationship, Drug; Electrophoresis, Gel, Two-Dimensional; Forkhead Box Protein O1; Forkhead Transcription Factors; Humans; Hydrogen Peroxide; KRIT1 Protein; Mesenchymal Stem Cells; Microtubule-Associated Proteins; Oxidants; Oxidative Stress; Proteomics; Proto-Oncogene Proteins; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Superoxide Dismutase; Transfection; Up-Regulation; Valproic Acid | 2015 |
The role and possible molecular mechanism of valproic acid in the growth of MCF-7 breast cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Caspase 3; Caspase 9; Cell Proliferation; Cyclin D1; Cyclin E; Female; G1 Phase Cell Cycle Checkpoints; Histone Deacetylase Inhibitors; Humans; MCF-7 Cells; Oncogene Proteins; Signal Transduction; Valproic Acid | 2017 |