valproic acid and clozapine

valproic acid has been researched along with clozapine in 119 studies

Research

Studies (119)

TimeframeStudies, this research(%)All Research%
pre-19902 (1.68)18.7374
1990's16 (13.45)18.2507
2000's42 (35.29)29.6817
2010's46 (38.66)24.3611
2020's13 (10.92)2.80

Authors

AuthorsStudies
Andrews, PR; Craik, DJ; Martin, JL1
Strassburg, CP; Tukey, RH1
Topliss, JG; Yoshida, F1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Andricopulo, AD; Moda, TL; Montanari, CA1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Glen, RC; Lowe, R; Mitchell, JB1
Ekins, S; Williams, AJ; Xu, JJ1
Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC1
Honda, K; Izumi, T; Miyaji, Y; Nakayama, S; Okazaki, O; Okudaira, N; Shiosakai, K; Sugiyama, D; Suzuki, W; Takakusa, H; Watanabe, A1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S1
Atzpodien, EA; Csato, M; Doessegger, L; Fischer, H; Lenz, B; Schmitt, G; Singer, T1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Filipek, B; Gunia-Krzyżak, A; Marona, H; Nitek, W; Pańczyk, K; Pękala, E; Rapacz, A; Słoczyńska, K; Waszkielewicz, AM; Żelaszczyk, D; Żesławska, E1
Fünfgeld, EW; Henkel, H; Kausen, J; Klenke, D; Zimmermann, P1
Longo, LP; Salzman, C1
Costello, LE; Suppes, T1
Finley, P; Warner, D1
Calabrese, JR; Woyshville, MJ1
Castillo, J; Centorrino, F; Kando, JC; Tohen, M1
Meltzer, HY; Ranjan, R1
Baldessarini, RJ; Centorrino, F; Cohen, BM; Flood, JG; Huston-Lyons, D; Volpicelli, SA1
Baldessarini, RJ; Centorrino, F; Flood, JG; Frankenburg, FR; Kando, J; Puopolo, PR; Volpicelli, SA1
Grimmell, K; Mazure, CM; Sernyak, M; Vojvoda, D1
Rush, AJ; Suppes, T1
Keck, PE; McElroy, SL; Strakowski, SM1
Freeman, MP; Stoll, AL1
Avenoso, A; Facciolà, G; Madia, AG; Perucca, E; Scordo, MG; Spina, E; Ventimiglia, A1
Deckert, J; Retz, W; Supprian, T1
Giannella, R; Lanzio, M; Maule, S; Villari, V1
Cagliero, E; Goff, DC; Gray, C; Hayden, DL; Henderson, DC; Nasrallah, RA; Schoenfeld, DA1
Ames, D; Bisheff, S; Mendoza, A; Pierre, JM; Sun, A; Wirshing, WC1
Calabrese, JR; Gajwani, P1
Ghaemi, SN; Guille, C; Sachs, GS1
Miller, PR1
Beraus, W; Conca, A; König, P; Waschgler, R1
Nemeroff, CB1
Ghaemi, SN1
Keunen, RW; Nicolai, J; Smith, SJ1
Adesanya, A; Pantelis, C1
Hirschmann, S; Kurs, R; Madeb, R; Modai, I; Turkie, A1
Freeman, MP; Gelenberg, AJ; Gnanadesikan, M1
Agam, G; Belmaker, RH; Kozlovsky, N; Nadri, C1
Fleischhacker, WW; Hofer, A; Hummer, M1
Grady, MM; Stahl, SM1
Botts, S; Coffey, G; de Leon, J1
Bryois, Ch; Sahli, Ch1
Brar, JS; Chengappa, KN; Imbarlina, MJ; Johnston, PR; Marwah, S; Parepally, H; Sarkar, S1
Foster, R; Olajide, D1
Begum, M1
Chan, YC; Hankins, MB; Miller, KM; Shaheen, N; Votolato, NA1
Danielyan, A; Kowatch, RA1
Chan, KT; Choi, WK; Hon-Kee Cheung, H; Lai, J; Leung, SP; Mak, T; Ng, RM; Wai-Kiu Tsang, A; Wong, JO1
Conley, RR; Feldman, S; Kelly, DL; McMahon, RP; Richardson, CM; Yu, Y1
Corona-Vazquez, T; Lopez-Meza, E; Ramirez-Bermudez, J; Ruano-Calderon, LA1
Bhatti, MA; Reeve, E; Zander, J1
Bajbouj, M; Danker-Hopfe, H; Gallinat, J; Hellen, F; Lang, UE; Lisanby, SH; Neu, P; Vesper, J1
Duggal, HS1
Dressing, H; Englisch, S; Knopf, U; Kuwilsky, A; Zink, M1
Durand, M; Forget, K; Grignon, S; Huppert, T1
Costa, E; Dong, E; Grayson, DR; Guidotti, A; Nelson, M1
Caetano, D1
Chan, WF; Chung, KF; Lai-wah Dunn, E; Pui-yin Chung, J; Shiu-yin Chong, C; Wai-nang Tang, O1
Hauser, D; Ladds, B; Mejia, C; Thomas, P1
Alvarez-Dobaño, JM; Arrojo-Romero, M; Carballal-Calvo, F; Codesido-Barcala, R; de Leon, J; Fernández-Pérez, R; Suárez-Antelo, J1
Grosić, V; Mihanović, M; Presecki, P; Silić, A1
Di Cosimo, D; Girardi, N; Kotzalidis, GD; Lazanio, S; Manfredi, G; Savoja, V; Talamo, A; Tatarelli, R; Vento, A1
Huff, W; Klosterkötter, J; Kuhn, J; Schilbach, L; Timmermann, L; Weiss, PH1
Rushlow, WJ; Sutton, LP1
Bowen, DJ; Braude, S; Lucas, NL1
Aydinoglu, U; Canan, F; Sinani, G1
Fitzgerald, PB; McNeil, JJ; Ronaldson, KJ; Taylor, AJ; Topliss, DJ; Wolfe, R1
Jacob, KS; Jacob, M; Kuruvilla, A; Poonkuzhali, B; Rajkumar, AP1
Akbarian, S; Halene, T; Hasan, A; Mitchell, A; Schneider, A1
Chen, CC; Chen, WJ; Kuo, CJ; Liao, YT; Liu, HC; Yang, SY1
Cooley, AT; de Leon, J; Riesselman, A; Strobl, B1
Allen, MB; Baker, JC; Nuernberger, JE; Vargo, KK1
Ene-Stroescu, V; Nguyen, T; Waiblinger, BE1
Cadilhe, DV; Cardoso, SC; Paulsen, Bda S; Rehen, SK; Stelling, MP1
Ansermot, N; Crettol, S; de Leon, J; Diaz, FJ; Eap, CB; Spina, E1
Campanella, D; De Berardis, D; Fornaro, M; Giannantonio, MD; Iasevoli, F; Martinotti, G; Napoletano, C; Olivieri, L; Rapini, G; Serroni, N; Valchera, A1
Joyce, DW; Mateos Fernandez, MJ; Sarkar, SN; Shergill, SS; Tracy, DK1
Gaughran, F; Gee, S; MacCabe, JH; Meyer, N; Mijovic, A; Shergill, S; Taylor, D; Whiskey, E1
Aebischer, B; Akboga, MK; Akdamar, G; Alcalay, RN; Álvarez-Pérez, S; Aydogdu, S; Balci, KG; Barcaro, G; Bišová, K; Blanco, JL; Brewer, SH; Caruthers, SD; Ceylan, O; Chadwick, JA; Chang, DD; Che, JM; Chen, QQ; Chen, W; Chen, Z; Chung, M; Chung, W; Colecraft, HM; Coteli, E; Dogan, H; Dong, S; Elsig, S; Fahn, S; Fang, XJ; Feng, MG; Fenlon, EE; Floyd, KT; Fokdal, L; Ford, B; Fortunelli, A; Freudenberg, R; Gan-Or, Z; García, ME; Gillham, C; Giovannelli, D; Goertz, RS; Gulati, V; Haie-Meder, C; Hao, YY; Hatano, K; Hines, KJ; Hines, SM; Hirakawa, H; Hoskin, P; Hu, JH; Huang, P; Huang, Y; Hubicka, U; Inoue, Y; Ishii, N; Janssen, PM; Jin, Z; Johnson, A; Jürgenliemk-Schultz, I; Kaineder, K; Kamei, K; Kang, U; Karatas, F; Kash, TL; Katayama, Y; Keupp, J; Kirisits, C; Kisacik, H; Kodama, K; Kotzerke, J; Kryczyk, A; Kuhness, D; Kuo, S; Lanza, GM; Le Bris, N; Levin, DE; Levy, OA; Li, B; Li, H; Li, X; Liang, GD; Liang, Y; Liao, RQ; Lin, JT; Lindegaard, JC; Liong, C; Liu, B; Liu, C; Liu, GH; Liu, L; Liu, Q; Liu, X; Lowe, J; Lowery-Gionta, EG; Ma, YH; Maden, O; Mankad, V; Marder, KS; Marshall, SA; Martínez-Nevado, E; Maucksch, U; Mazeron, R; Mazzone, CM; Mazzoni, P; Mezricky, D; Mizokami, Y; Naumann, A; Navarro, M; Netzer, FP; Neurath, MF; Nie, Q; Oliva, P; Ozeke, O; Peláez, T; Pfeifer, L; Pleil, KE; Pomp, S; Pötter, R; Puckerin, AA; Rafael-Fortney, JA; Raman, SV; Rastogi, N; Řezanka, M; Řezanka, T; Rinker, JA; Rouleau, GA; Runge, R; Sahin, MD; Sakai, A; Schmieder, AH; Schmitz, AJ; Schultz, EJ; Šegedin, B; Sementa, L; Shen, Y; Shiotsuki, I; Shirahama, M; Staley, J; Starovoytov, V; Sterrer, M; Strobel, D; Sturdza, A; Subramanyam, P; Surnev, S; Swager, SA; Taeymans, J; Tan, H; Tan, LT; Tanderup, K; Temizhan, A; Terao, T; Thiele, TE; Tran, T; Tucker, MJ; Vetriani, C; Vítová, M; Wang, JP; Wang, L; Wang, M; Wang, X; Waters, CH; Weng, SX; Wickline, SA; Wildner, D; Wodarcyk, AJ; Wolf, P; Wu, L; Wu, YL; Wunderlich, G; Xiong, L; Xu, P; Yang, GS; Yang, XN; Yang, Y; Yayla, C; Ying, SH; Zachleder, V; Zhang, XG; Zhang, XK; Zhang, Y; Zheng, JY; Zhong, WZ; Zhu, J; Zhu, YJ; Żmudzki, P1
de Leon, J; Lana, F; Martí-Bonany, J1
Kanofsky, JD; Woesner, ME1
Ajnakina, O; Flanagan, RJ; Gaughran, F; Krivoy, A; Lally, J; MacCabe, JH; Malik, S; Pritchard, M; Shetty, H1
Akhavanrezayat, A; Amlashi, SV; Behdani, F; Ferns, GA; Ghayour-Mobarhan, M; Hebrani, P; Roudbaraki, SN; Saberi-Karimian, M; Tayefi, M1
Baroni, S; Betti, L; Ciapparelli, A; DellʼOsso, L; Giannaccini, G; Lucacchini, A; Marazziti, D; Massimetti, E; Mucci, F; Palego, L1
Deckert, J; Fischer, M; Hefner, G; Hohner, M; Hommers, L; Pfuhlmann, B; Scharl, M; Unterecker, S1
Chen, RYY; Reznik, R; Stanford, P1
Chung, IW; Jeong, SH; Jeong, SW; Jung, HY; Kim, HS; Kim, KK; Kim, SH; Kim, YS; Youn, T1
Benyamina, A; Martelli, C; Petillion, A; Roméo, B1
Andreassen, OA; Haslemo, T; Kyllesø, L; Molden, E; Smith, RL1
Ağaoğlu, E; Ak, S; Anıl Yağcıoğlu, AE; Ertuğrul, A; Karahan, S; Karakaşlı, AA; Yazıcı, MK1
de Leon, J1
Jahołkowski, P; Kowalski, M; Niewiadomska, J; Świtaj, P; Wciórka, J1
Fukuyama, K; Murata, M; Okada, M; Okubo, R; Shiroyama, T1
Chen, HZ; Chen, YQ; Deng, SH; Fang, ZY; Hu, JQ; Li, L; Lu, HY; Shang, DW; Wang, ZZ; Wen, YG; Xie, HS; Zhang, M; Zhu, XQ1
Ateb, S; Baha, D; Ben Rejeb, H; Benadhira, R; Bouaziz, N; Chammas, F; Fourati, T; Januel, D; Kalalou, K; Rosetti, R; Saba, G1
Andrade, G; Câmara-Pestana, L; Simões do Couto, F1
Adebayo, RA; Anıl Yağcıoğlu, AE; Arrojo-Romero, M; Ayub, M; Baptista, T; Bebawi, E; Bhattacharya, R; Bilbily, J; Bonelli, RM; Bousman, CA; Buckley, PF; Celofiga, A; Chan, SKW; Chopra, N; Citrome, L; Cohen, D; Correll, CU; Cotes, RO; Crespo-Facorro, B; Cubała, WJ; De Berardis, D; De Las Cuevas, C; de Leon, J; Decloedt, E; Eap, CB; Elkis, H; Ertuğrul, A; Every-Palmer, S; Farooq, S; Fernandez-Egea, E; Fountoulakis, KN; Freudenreich, O; González-Esquivel, DF; Grover, S; Gründer, G; Hiemke, C; Iglesias-Alonso, A; Iglesias-Garcia, C; Ignjatovic Ristic, D; Jung-Cook, H; Kaithi, AR; Kane, JM; Kelly, DL; Kim, SH; Kim, YS; Kirilochev, OO; Kopeček, M; Lana, F; Lane, HY; Lazary, J; Leung, JG; Lin, SK; LLerena, A; López-Jaramillo, C; Marder, SR; Masmoudi, R; McCollum, B; McGrane, I; Mohd Saffian, S; Molden, E; Motuca, M; Müller, DJ; Ng, CH; Nielsen, J; Olmos, I; Ortiz, BB; Otsuka, Y; Ouanes, S; Pacheco Palha, AJ; Pedro, MR; Procyshyn, RM; Quiles, C; Rădulescu, FŞ; Rajkumar, AP; Ricciardi, C; Rohde, C; Ruan, CJ; Sagud, M; Sanz, EJ; Schoretsanitis, G; Schulte, PFJ; Seifritz, E; Seppälä, N; Shelton, C; Silva, A; Siskind, D; Smith, RL; Solismaa, A; Soloviev, A; Spina, E; Švancer, P; Takeuchi, H; Tang, YL; Temmingh, H; Torres, R; Tsukahara, M; Verdoux, H; Villagrán-Moreno, JM; Wang, CY; Wang, G; Weizman, A; Wilkowska, A; Yecora, A; Zolezzi, M1
Eriksson, L; Malacova, E; McMahon, K; Moudgil, V; Ramineni, V; Scott, J; Siskind, D; Vickers, M1
Coleman, JK; Cotes, RO; De Leon, J; Goldsmith, DR; Koenig, M; McCollum, B; Shelton, C; Spivey, JK1
Cirujeda, C; Concha, J; García, CB; Padilla, PP; Ribate, MP; Sangüesa, E1
Anver, PC; Moideen, S; Uvais, NA1
Chou, PH; Lin, CH; Wang, XY; Yang, CC1
Kishi, Y; Kodama, M; Nakajima, S; So, R; Takeda, T; Takeuchi, H; Tsukahara, M; Yada, Y; Yamada, N; Yamashita, R; Yoshimura, Y1
Jovanović, M; Lukić, V; Miljković, B; Milovanović, S; Panić, B; Vučićević, K1

Reviews

15 review(s) available for valproic acid and clozapine

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
A medication algorithm for treatment of bipolar rapid cycling?
    The Journal of clinical psychiatry, 1995, Volume: 56 Suppl 3

    Topics: Algorithms; Bipolar Disorder; Carbamazepine; Clozapine; Controlled Clinical Trials as Topic; Drug Administration Schedule; Drug Therapy, Combination; Electroconvulsive Therapy; Humans; Lithium; Treatment Outcome; Valproic Acid

1995
New developments in the pharmacologic treatment of schizoaffective disorder.
    The Journal of clinical psychiatry, 1996, Volume: 57 Suppl 9

    Topics: Antidepressive Agents; Antipsychotic Agents; Carbamazepine; Clinical Trials as Topic; Clozapine; Drug Therapy, Combination; Humans; Psychotic Disorders; Receptors, Serotonin; Risperidone; Serotonin Antagonists; Treatment Outcome; Valproic Acid

1996
Mood stabilizer combinations: a review of safety and efficacy.
    The American journal of psychiatry, 1998, Volume: 155, Issue:1

    Topics: Acetates; Amines; Anticonvulsants; Antipsychotic Agents; Bipolar Disorder; Calcium Channel Blockers; Clinical Trials as Topic; Clozapine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Lithium; Risperidone; Valproic Acid

1998
An ever-increasing pharmacopoeia for the management of patients with bipolar disorder.
    The Journal of clinical psychiatry, 2000, Volume: 61 Supp 13

    Topics: Acetates; Amines; Anticonvulsants; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Carbamazepine; Clozapine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Electroconvulsive Therapy; Electromagnetic Phenomena; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Lithium; Olanzapine; Pirenzepine; Risperidone; Topiramate; Treatment Outcome; Triazines; Valproic Acid

2000
New treatments for bipolar disorder: the role of atypical neuroleptic agents.
    The Journal of clinical psychiatry, 2000, Volume: 61 Suppl 14

    Topics: Acute Disease; Algorithms; Anticonvulsants; Antidepressive Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Clozapine; Dibenzothiazepines; Drug Therapy, Combination; Humans; Lithium; Olanzapine; Pirenzepine; Psychotic Disorders; Quetiapine Fumarate; Risperidone; Treatment Outcome; Valproic Acid

2000
Alternatives to lithium and divalproex in the maintenance treatment of bipolar disorder.
    Bipolar disorders, 2003, Volume: 5, Issue:3

    Topics: Acetates; Amines; Anticonvulsants; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Calcium Channel Blockers; Carbamazepine; Clozapine; Cyclohexanecarboxylic Acids; Dibenzothiazepines; Donepezil; Fatty Acids, Omega-3; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Indans; Lamotrigine; Lithium Carbonate; Olanzapine; Piperazines; Piperidines; Pirenzepine; Quetiapine Fumarate; Risperidone; Thiazoles; Topiramate; Treatment Outcome; Triazines; Valproic Acid

2003
A critical review of atypical antipsychotic utilization: comparing monotherapy with polypharmacy and augmentation.
    Current medicinal chemistry, 2004, Volume: 11, Issue:3

    Topics: Acetates; Amines; Anticonvulsants; Antipsychotic Agents; Clinical Trials as Topic; Clozapine; Cyclohexanecarboxylic Acids; Drug Utilization; Gabapentin; gamma-Aminobutyric Acid; Humans; Polypharmacy; Risperidone; Schizophrenia; Valproic Acid

2004
[Psychotropics and weight gain].
    Praxis, 2004, Aug-25, Volume: 93, Issue:35

    Topics: Adolescent; Adult; Amisulpride; Antidepressive Agents; Antimanic Agents; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Body Mass Index; Child; Clozapine; Dibenzothiazepines; Double-Blind Method; Female; Fructose; Haloperidol; Humans; Imidazoles; Indoles; Male; Obesity; Olanzapine; Piperazines; Placebos; Psychotropic Drugs; Quetiapine Fumarate; Quinolones; Randomized Controlled Trials as Topic; Risperidone; Socioeconomic Factors; Sulpiride; Thiazoles; Time Factors; Topiramate; Valproic Acid; Weight Gain

2004
Management options for bipolar disorder in children and adolescents.
    Paediatric drugs, 2005, Volume: 7, Issue:5

    Topics: Adolescent; Benzodiazepines; Bipolar Disorder; Carbamazepine; Child; Clozapine; Dibenzothiazepines; Humans; Lithium; Olanzapine; Quetiapine Fumarate; Risperidone; Valproic Acid

2005
Epigenetic dysregulation in schizophrenia: molecular and clinical aspects of histone deacetylase inhibitors.
    European archives of psychiatry and clinical neuroscience, 2013, Volume: 263, Issue:4

    Topics: Antipsychotic Agents; Clozapine; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Epigenesis, Genetic; gamma-Aminobutyric Acid; Histone Deacetylase Inhibitors; Histones; Humans; Protein Processing, Post-Translational; Schizophrenia; Valproic Acid

2013
    Hand therapy, 2016, Volume: 21, Issue:1

    Topics: AC133 Antigen; Acenaphthenes; Acer; Acrosome Reaction; Adult; Agaricales; Aged; Aged, 80 and over; Animals; Animals, Zoo; Anti-Bacterial Agents; Anticoagulants; Antifungal Agents; Antimanic Agents; Antioxidants; Aortic Valve; Area Under Curve; ATP Binding Cassette Transporter, Subfamily G, Member 2; Bacillus; Bacterial Toxins; Bacterial Typing Techniques; Base Composition; Beauveria; Binge Drinking; Biomarkers; Bipolar Disorder; Blood Coagulation; Blotting, Western; Brachytherapy; Calcium Channels, L-Type; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Cell Wall; Cells, Cultured; Ceramics; Chi-Square Distribution; China; Chlorophyll; Chlorophyta; Chloroplasts; Cholesterol, HDL; Chromatography, High Pressure Liquid; Chromobacterium; Clostridium perfringens; Clozapine; Constriction, Pathologic; Coronary Artery Bypass; Corticotropin-Releasing Hormone; Cross-Sectional Studies; Cytochrome P-450 CYP2C9; Dental Porcelain; Dental Restoration Failure; Dental Stress Analysis; Designer Drugs; Diaminopimelic Acid; DNA Fingerprinting; DNA, Bacterial; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Dosage Calculations; Drug Evaluation, Preclinical; Drug Resistance, Bacterial; Elasticity Imaging Techniques; Epsilonproteobacteria; Equipment Design; Ericaceae; Excitatory Amino Acid Antagonists; False Negative Reactions; Fatty Acids; Female; Food Analysis; Fresh Water; Gene Expression Regulation, Neoplastic; Glutathione; Graft Occlusion, Vascular; Heart Valve Prosthesis Implantation; Heart Ventricles; HEK293 Cells; Hemolymph; Humans; Hyaluronan Receptors; Hydrogen Peroxide; Hydrothermal Vents; Indoles; Inflammation Mediators; Inhibitory Concentration 50; Insecta; International Normalized Ratio; Isotope Labeling; Itraconazole; Kidney; Kinetics; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Lamotrigine; Lanthanoid Series Elements; Limit of Detection; Linear Models; Lipid Peroxidation; Liver; Liver Cirrhosis; Logistic Models; Lung Neoplasms; Lymph Node Excision; Lymphatic Metastasis; Male; Malondialdehyde; Mediastinum; Metronidazole; Mice; Mice, Nude; Mice, Transgenic; Microbial Sensitivity Tests; Microscopy, Fluorescence; Middle Aged; Monocytes; Monomeric GTP-Binding Proteins; Multivariate Analysis; Myocytes, Cardiac; Neoplasm Staging; Neoplastic Stem Cells; Neural Pathways; Nitrates; Nucleic Acid Hybridization; Octamer Transcription Factor-3; Odds Ratio; Oxidation-Reduction; Oxidative Stress; Peptidoglycan; Phantoms, Imaging; Pharmacogenetics; Pharmacogenomic Variants; Phenotype; Phospholipids; Photolysis; Photosynthesis; Phylogeny; Plant Extracts; Polychaeta; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Positron Emission Tomography Computed Tomography; Predictive Value of Tests; Preoperative Care; Prostatic Neoplasms; Pseudomonas aeruginosa; Pyrimidines; Pyrroles; Quorum Sensing; Radiology, Interventional; Radiopharmaceuticals; Radiotherapy Dosage; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Reference Values; Regression Analysis; Retrospective Studies; Reverse Transcriptase Polymerase Chain Reaction; Rhizosphere; Risk Factors; RNA, Ribosomal, 16S; ROC Curve; Rutin; Saphenous Vein; Seawater; Selenium; Semen Preservation; Sensitivity and Specificity; Septal Nuclei; Sequence Analysis, DNA; Serum Albumin; Serum Albumin, Human; Shear Strength; Sodium Pertechnetate Tc 99m; Sodium-Hydrogen Exchangers; Soil Microbiology; SOXB1 Transcription Factors; Spain; Species Specificity; Sperm Motility; Spermatozoa; Spheroids, Cellular; Spores, Fungal; Stroke; Superoxide Dismutase; Swine; Tandem Mass Spectrometry; Technetium Compounds; Technetium Tc 99m Exametazime; Technetium Tc 99m Sestamibi; Temperature; Thiosulfates; Thrombosis; Thyroid Neoplasms; Transducers; Transfection; Transplantation, Heterologous; Treatment Outcome; Triazines; Tumor Burden; Urocortins; Uterine Cervical Neoplasms; Vacuoles; Valproic Acid; Ventral Tegmental Area; Vitamin K 2; Vitamin K Epoxide Reductases; Warfarin; Water Microbiology; Young Adult

2016
[Recommendations about the Use of Psychotropic Medications during the COVID-19 Pandemic].
    Acta medica portuguesa, 2020, Oct-01, Volume: 33, Issue:10

    Topics: Antiviral Agents; Benzodiazepines; Betacoronavirus; Bipolar Disorder; Body Temperature Regulation; Buprenorphine; Clozapine; Coronavirus Infections; COVID-19; Delayed-Action Preparations; Drug Interactions; Hospitalization; Humans; Lithium Compounds; Mental Disorders; Methadone; Narcotic Antagonists; Pandemics; Pneumonia, Viral; Psychotropic Drugs; SARS-CoV-2; Schizophrenia; Smoking Cessation Agents; Valproic Acid

2020
Risk factors for clozapine-induced myocarditis and cardiomyopathy: A systematic review and meta-analysis.
    Acta psychiatrica Scandinavica, 2022, Volume: 145, Issue:5

    Topics: Antipsychotic Agents; Cardiomyopathies; Clozapine; Humans; Myocarditis; Risk Factors; Valproic Acid

2022

Trials

6 trial(s) available for valproic acid and clozapine

ArticleYear
Serum concentrations of clozapine and its major metabolites: effects of cotreatment with fluoxetine or valproate.
    The American journal of psychiatry, 1994, Volume: 151, Issue:1

    Topics: Adult; Clozapine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluoxetine; Humans; Male; Psychotic Disorders; Schizophrenia; Stimulation, Chemical; Valproic Acid

1994
Small effects of valproic acid on the plasma concentrations of clozapine and its major metabolites in patients with schizophrenic or affective disorders.
    Therapeutic drug monitoring, 1999, Volume: 21, Issue:3

    Topics: Adult; Anticonvulsants; Antipsychotic Agents; Clozapine; Drug Interactions; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Mood Disorders; Schizophrenia; Valproic Acid

1999
Clozapine, diabetes mellitus, weight gain, and lipid abnormalities: A five-year naturalistic study.
    The American journal of psychiatry, 2000, Volume: 157, Issue:6

    Topics: Adult; Age Factors; Antipsychotic Agents; Body Mass Index; Body Weight; Cholesterol; Clozapine; Diabetes Mellitus; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Family; Female; Genetic Predisposition to Disease; Humans; Hypercholesterolemia; Hypertriglyceridemia; Incidence; Male; Obesity; Psychotic Disorders; Risk Factors; Schizophrenia; Triglycerides; Valproic Acid

2000
A naturalistic comparison of clozapine, risperidone, and olanzapine in the treatment of bipolar disorder.
    The Journal of clinical psychiatry, 2000, Volume: 61, Issue:9

    Topics: Adult; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Bipolar Disorder; Body Weight; Clozapine; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Lithium; Male; Olanzapine; Pirenzepine; Psychiatric Status Rating Scales; Retrospective Studies; Risperidone; Treatment Outcome; Valproic Acid

2000
Motor cortex excitability after vagus nerve stimulation in major depression.
    Journal of clinical psychopharmacology, 2007, Volume: 27, Issue:2

    Topics: Adult; Benzodiazepines; Citalopram; Clomipramine; Clozapine; Depressive Disorder; Doxepin; Drug Therapy, Combination; Electric Stimulation; Female; Humans; Lamotrigine; Lithium Carbonate; Male; Mianserin; Middle Aged; Mirtazapine; Morpholines; Motor Cortex; Neural Conduction; Neural Inhibition; Olanzapine; Paroxetine; Psychiatric Status Rating Scales; Reboxetine; Tranylcypromine; Triazines; Vagus Nerve; Valproic Acid

2007
Assessment of the efficacy of omega-3 fatty acids on metabolic and inflammatory parameters in patients with schizophrenia taking clozapine and sodium valproate.
    Psychiatry research, 2018, Volume: 261

    Topics: Adult; Anthropometry; Antipsychotic Agents; Body Mass Index; Body Weight; C-Reactive Protein; Clozapine; Dietary Supplements; Double-Blind Method; Fasting; Fatty Acids, Omega-3; Female; Humans; Male; Middle Aged; Schizophrenia; Treatment Outcome; Triglycerides; Valproic Acid; Waist Circumference

2018

Other Studies

98 other study(ies) available for valproic acid and clozapine

ArticleYear
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
    Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24

    Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility

2010
Combination of GSH trapping and time-dependent inhibition assays as a predictive method of drugs generating highly reactive metabolites.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:7

    Topics: Glutathione; Pharmacology; Sulfur Radioisotopes

2011
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors

2012
In silico assay for assessing phospholipidosis potential of small druglike molecules: training, validation, and refinement using several data sets.
    Journal of medicinal chemistry, 2012, Jan-12, Volume: 55, Issue:1

    Topics: Animals; Cattle; Cells, Cultured; Computer Simulation; Cornea; Drug-Related Side Effects and Adverse Reactions; Fibroblasts; Lipidoses; Lysosomal Storage Diseases; Models, Molecular; Pharmaceutical Preparations; Phospholipids; Structure-Activity Relationship; Thermodynamics

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Structure-anticonvulsant activity studies in the group of (E)-N-cinnamoyl aminoalkanols derivatives monosubstituted in phenyl ring with 4-Cl, 4-CH
    Bioorganic & medicinal chemistry, 2017, 01-15, Volume: 25, Issue:2

    Topics: Amino Alcohols; Animals; Anticonvulsants; Crystallography, X-Ray; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Mice; Models, Molecular; Molecular Structure; Rats; Seizures; Structure-Activity Relationship

2017
Effects of a GABA-mimetic drug (sodium valproate) on visually evoked potentials in chronic schizophrenics.
    Neuropsychobiology, 1984, Volume: 11, Issue:1

    Topics: Adult; Brain; Brief Psychiatric Rating Scale; Chronic Disease; Clozapine; Dibenzazepines; Drug Therapy, Combination; Evoked Potentials, Visual; Female; gamma-Aminobutyric Acid; Humans; Middle Aged; Schizophrenia; Valproic Acid

1984
Valproic acid effects on serum concentrations of clozapine and norclozapine.
    The American journal of psychiatry, 1995, Volume: 152, Issue:4

    Topics: Clozapine; Depression, Chemical; Drug Therapy, Combination; Humans; Schizophrenia; Seizures; Valproic Acid

1995
A clinically significant interaction between clozapine and valproate.
    Journal of clinical psychopharmacology, 1995, Volume: 15, Issue:2

    Topics: Adult; Arousal; Bipolar Disorder; Clozapine; Confusion; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Humans; Lithium; Male; Orientation; Psychotic Disorders; Speech Disorders; Valproic Acid

1995
Potential impact of valproic acid therapy on clozapine disposition.
    Biological psychiatry, 1994, Oct-01, Volume: 36, Issue:7

    Topics: Adult; Clozapine; Drug Interactions; Humans; Male; Middle Aged; Pilot Projects; Schizophrenia; Valproic Acid

1994
Concurrent use of clozapine and valproate in affective and psychotic disorders.
    The Journal of clinical psychiatry, 1994, Volume: 55, Issue:6

    Topics: Adult; Clozapine; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Incidence; Leukopenia; Liver; Liver Function Tests; Male; Middle Aged; Psychotic Disorders; Seizures; Sleep; Treatment Outcome; Valproic Acid

1994
Valproic acid treatment of clozapine-induced myoclonus.
    The American journal of psychiatry, 1994, Volume: 151, Issue:8

    Topics: Adult; Clozapine; Drug Administration Schedule; Female; Humans; Myoclonus; Receptors, Serotonin; Schizophrenia; Seizures; Valproic Acid

1994
Tissue concentrations of clozapine and its metabolites in the rat.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1993, Volume: 9, Issue:2

    Topics: Animals; Brain; Clozapine; Fluoxetine; Half-Life; Male; Mass Spectrometry; Rats; Rats, Sprague-Dawley; Valproic Acid

1993
Monozygotic twins concordant for response to clozapine.
    Lancet (London, England), 1996, Jan-06, Volume: 347, Issue:8993

    Topics: Adult; Antipsychotic Agents; Clozapine; Diseases in Twins; Drug Therapy, Combination; Humans; Male; Schizophrenia; Twins, Monozygotic; Valproic Acid

1996
Medication optimization during clozapine treatment.
    The Journal of clinical psychiatry, 1996, Volume: 57, Issue:7

    Topics: 1-Naphthylamine; Adult; Clozapine; Drug Therapy, Combination; Humans; Lithium; Male; Obsessive-Compulsive Disorder; Psychotic Disorders; Selective Serotonin Reuptake Inhibitors; Sertraline; Treatment Outcome; Valproic Acid

1996
Clozapine-induced stuttering: epileptic brain activity?
    The American journal of psychiatry, 1999, Volume: 156, Issue:10

    Topics: Anticonvulsants; Antipsychotic Agents; Brain; Clozapine; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy, Generalized; Female; Humans; Middle Aged; Phenytoin; Schizophrenia, Paranoid; Stuttering; Valproic Acid

1999
Diabetic ketoacidosis with clozapine treatment.
    Diabetes, nutrition & metabolism, 1999, Volume: 12, Issue:2

    Topics: Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Clozapine; Diabetic Ketoacidosis; Drug Therapy, Combination; Female; Humans; Middle Aged; Valproic Acid

1999
Hepatic encephalopathy associated with combined clozapine and divalproex sodium treatment.
    Journal of clinical psychopharmacology, 1997, Volume: 17, Issue:2

    Topics: Adult; Clozapine; Drug Interactions; Enzyme Inhibitors; Female; Hepatic Encephalopathy; Humans; Serotonin Antagonists; Valproic Acid

1997
Lamotrigine and clozapine for bipolar disorder.
    The American journal of psychiatry, 2000, Volume: 157, Issue:9

    Topics: Antidepressive Agents; Antipsychotic Agents; Bipolar Disorder; Clozapine; Drug Therapy, Combination; Humans; Lamotrigine; Male; Middle Aged; Treatment Outcome; Triazines; Valproic Acid

2000
Clozapine therapy for a patient with a history of Hodgkin's disease.
    Psychiatric services (Washington, D.C.), 2001, Volume: 52, Issue:1

    Topics: Adult; Antipsychotic Agents; Bipolar Disorder; Clozapine; Drug Therapy, Combination; Female; Hodgkin Disease; Humans; Leukopenia; Remission Induction; Risperidone; Treatment Outcome; Valproic Acid

2001
A case of pharmacokinetic interference in comedication of clozapine and valproic acid.
    Pharmacopsychiatry, 2000, Volume: 33, Issue:6

    Topics: Adult; Anticonvulsants; Clozapine; Drug Interactions; Drug Therapy, Combination; Epilepsy, Generalized; Female; GABA Antagonists; Humans; Valproic Acid

2000
Simultaneous side effects of both clozapine and valproate.
    Intensive care medicine, 2001, Volume: 27, Issue:5

    Topics: Adult; Anticonvulsants; Antipsychotic Agents; Carnitine; Clozapine; Coma; Diabetic Ketoacidosis; Drug Interactions; Humans; Hyperammonemia; Male; Valproic Acid

2001
Increased risk of neutropaenia and agranulocytosis with sodium valproate used adjunctively with clozapine.
    The Australian and New Zealand journal of psychiatry, 2001, Volume: 35, Issue:4

    Topics: Adult; Agranulocytosis; Anticonvulsants; Antipsychotic Agents; Clozapine; Drug Therapy, Combination; Female; Humans; Neutropenia; Risk Factors; Schizophrenia; Valproic Acid

2001
Combined clozapine and valproic acid treatment-induced agranulocytosis.
    European psychiatry : the journal of the Association of European Psychiatrists, 2002, Volume: 17, Issue:4

    Topics: Agranulocytosis; Anticonvulsants; Chronic Disease; Clozapine; Drug Therapy, Combination; Humans; Male; Middle Aged; Schizophrenia, Paranoid; Serotonin Antagonists; Valproic Acid

2002
Lack of effect of mood stabilizers or neuroleptics on GSK-3 protein levels and GSK-3 activity.
    The international journal of neuropsychopharmacology, 2003, Volume: 6, Issue:2

    Topics: Affect; Animals; Antimanic Agents; Antipsychotic Agents; Blotting, Western; Chlorpromazine; Clozapine; Frontal Lobe; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Haloperidol; Lithium; Rats; Rats, Sprague-Dawley; Valproic Acid

2003
Worsening of psychosis after replacement of adjunctive valproate with topiramate in a schizophrenia patient.
    The Journal of clinical psychiatry, 2003, Volume: 64, Issue:10

    Topics: Adult; Anticonvulsants; Clozapine; Disease Progression; Dose-Response Relationship, Drug; Drug Therapy, Combination; Fructose; Humans; Male; Psychiatric Status Rating Scales; Schizophrenia, Paranoid; Sertraline; Topiramate; Valproic Acid

2003
Dosing differences between valproic acid concentrate and divalproex sodium: a case report.
    The Journal of clinical psychiatry, 2004, Volume: 65, Issue:5

    Topics: Administration, Oral; Adult; Antipsychotic Agents; Biological Availability; Clozapine; Delayed-Action Preparations; Dose-Response Relationship, Drug; Humans; Intestinal Absorption; Male; Schizophrenia; Seizures; Valproic Acid

2004
Leukopenia in clozapine treated patients may be induced by other drugs: a case series.
    European psychiatry : the journal of the Association of European Psychiatrists, 2004, Volume: 19, Issue:8

    Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Clozapine; Drug Resistance; Female; Humans; Leukocyte Count; Leukopenia; Lithium Carbonate; Male; Middle Aged; Valproic Acid

2004
A case of clozapine-induced tonic-clonic seizures managed with valproate: implications for clinical care.
    Journal of psychopharmacology (Oxford, England), 2005, Volume: 19, Issue:1

    Topics: Adult; Anticonvulsants; Antipsychotic Agents; Clozapine; Epilepsy, Tonic-Clonic; Female; Humans; Schizophrenia, Paranoid; Valproic Acid

2005
Clozapine-induced stuttering, facial tics and myoclonic seizures: a case report.
    The Australian and New Zealand journal of psychiatry, 2005, Volume: 39, Issue:3

    Topics: Antipsychotic Agents; Clozapine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsies, Myoclonic; Humans; Male; Schizophrenia; Stuttering; Tics; Valproic Acid

2005
Worsening of psychotic symptoms in schizophrenia with addition of lamotrigine: a case report.
    Schizophrenia research, 2005, Oct-15, Volume: 78, Issue:2-3

    Topics: Adult; Antipsychotic Agents; Brain; Clozapine; Drug Therapy, Combination; Female; Humans; Lamotrigine; Lithium Carbonate; Magnetic Resonance Imaging; Psychotic Disorders; Schizophrenia; Severity of Illness Index; Triazines; Valproic Acid

2005
Plasma clozapine levels and clinical response in treatment-refractory Chinese schizophrenic patients.
    Progress in neuro-psychopharmacology & biological psychiatry, 2006, Volume: 30, Issue:2

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Antipsychotic Agents; China; Chromatography, High Pressure Liquid; Clozapine; Drug Interactions; Electrochemistry; Female; Humans; Male; Middle Aged; ROC Curve; Schizophrenia; Sensitivity and Specificity; Statistics, Nonparametric; Time Factors; Valproic Acid

2006
Adjunct divalproex or lithium to clozapine in treatment-resistant schizophrenia.
    The Psychiatric quarterly, 2006,Spring, Volume: 77, Issue:1

    Topics: Adult; Anticonvulsants; Antimanic Agents; Antipsychotic Agents; Anxiety; Blood Glucose; Brief Psychiatric Rating Scale; Clozapine; Drug Resistance; Drug Therapy, Combination; Female; Hostility; Humans; Lithium Carbonate; Male; Middle Aged; Prospective Studies; Retrospective Studies; Schizophrenia; Schizophrenic Psychology; Valproic Acid; Weight Gain

2006
Severe impulsiveness as the primary manifestation of multiple sclerosis in a young female.
    Psychiatry and clinical neurosciences, 2005, Volume: 59, Issue:6

    Topics: Adolescent; Adult; Antimanic Agents; Antipsychotic Agents; Child; Clozapine; Female; Homicide; Humans; Impulsive Behavior; Magnetic Resonance Imaging; Masturbation; Multiple Sclerosis; Personality; Psychotropic Drugs; Sex Work; Sexual Behavior; Substance-Related Disorders; Suicide; Valproic Acid

2005
Clozapine-induced pericarditis, pericardial tamponade, polyserositis, and rash.
    The Journal of clinical psychiatry, 2005, Volume: 66, Issue:11

    Topics: Adult; Anticonvulsants; Antipsychotic Agents; Cardiac Tamponade; Clozapine; Drug Eruptions; Drug Therapy, Combination; Female; Humans; Pericardial Effusion; Pericarditis; Pleural Effusion; Schizophrenia; Serositis; Valproic Acid

2005
Glycopyrrolate for clozapine-induced sialorrhea.
    Progress in neuro-psychopharmacology & biological psychiatry, 2007, Oct-01, Volume: 31, Issue:7

    Topics: Adult; Antimanic Agents; Antipsychotic Agents; Clozapine; Fluphenazine; Glycopyrrolate; Humans; Male; Muscarinic Antagonists; Psychotic Disorders; Sialorrhea; Valproic Acid

2007
Augmentation of clozapine with valproic Acid for clozapine-induced obsessive-compulsive symptoms.
    Pharmacopsychiatry, 2007, Volume: 40, Issue:5

    Topics: Adult; Antimanic Agents; Antipsychotic Agents; Clozapine; Drug Therapy, Combination; Humans; Male; Obsessive-Compulsive Disorder; Psychiatric Status Rating Scales; Schizophrenia; Valproic Acid

2007
Increased left prefrontal activation during staring/mutism episodes in a patient with resistant catatonic schizophrenia: a near infrared spectroscopy study.
    Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology, 2008, Volume: 21, Issue:1

    Topics: Adult; Attention; Awareness; Catalepsy; Clozapine; Combined Modality Therapy; Dominance, Cerebral; Drug Resistance; Electroconvulsive Therapy; Fixation, Ocular; Humans; Image Processing, Computer-Assisted; Imaging, Three-Dimensional; Lorazepam; Male; Mutism; Oxyhemoglobins; Prefrontal Cortex; Regional Blood Flow; Schizophrenia, Catatonic; Spectroscopy, Near-Infrared; Valproic Acid

2008
Clozapine and sulpiride but not haloperidol or olanzapine activate brain DNA demethylation.
    Proceedings of the National Academy of Sciences of the United States of America, 2008, Sep-09, Volume: 105, Issue:36

    Topics: Acetylation; Animals; Benzodiazepines; Brain; Cell Adhesion Molecules, Neuronal; Clozapine; DNA Methylation; Extracellular Matrix Proteins; Glutamate Decarboxylase; Haloperidol; Histones; Lysine; Male; Mice; Nerve Tissue Proteins; Olanzapine; Promoter Regions, Genetic; Reelin Protein; Serine Endopeptidases; Sulpiride; Valproic Acid

2008
Adjunctive medication effects may increase risk for neutropenia.
    The American journal of psychiatry, 2008, Volume: 165, Issue:12

    Topics: Antipsychotic Agents; Chemotherapy, Adjuvant; Clozapine; Drug Administration Schedule; Humans; Neutropenia; Psychotic Disorders; Risk Factors; Valproic Acid

2008
The incidence and characteristics of clozapine- induced fever in a local psychiatric unit in Hong Kong.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 2008, Volume: 53, Issue:12

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Antipsychotic Agents; Bipolar Disorder; Clozapine; Cross-Sectional Studies; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Fever; Hong Kong; Humans; Incidence; Male; Middle Aged; Psychiatric Department, Hospital; Psychotic Disorders; Retrospective Studies; Risk Factors; Schizophrenia; Valproic Acid; Young Adult

2008
Extreme elevation of creatinine phosphokinase levels in neuroleptic malignant syndrome associated with atypical antipsychotics.
    The American journal of psychiatry, 2009, Volume: 166, Issue:1

    Topics: Adult; Antipsychotic Agents; Aripiprazole; Clozapine; Creatine Kinase; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Humans; Male; Myocardial Infarction; Neuroleptic Malignant Syndrome; Piperazines; Quinolones; Risperidone; Schizophrenia; Valproic Acid

2009
Eosinophilic pleural effusion associated with the addition of sodium valproate.
    Journal of clinical psychopharmacology, 2009, Volume: 29, Issue:3

    Topics: Antimanic Agents; Antipsychotic Agents; Clozapine; Drug Therapy, Combination; Eosinophilia; Female; Humans; Middle Aged; Pleural Effusion; Valproic Acid

2009
Infection or idiosyncratic reaction to antiepileptic drugs?
    Psychiatria Danubina, 2010, Volume: 22, Issue:1

    Topics: Adult; Anticonvulsants; Antipsychotic Agents; Bipolar Disorder; Clozapine; Diagnosis, Differential; Drug Therapy, Combination; Humans; Lamotrigine; Male; Pericarditis; Respiratory Insufficiency; Systemic Inflammatory Response Syndrome; Triazines; Valproic Acid

2010
Folie à deux: double case-report of shared delusions with a fatal outcome.
    La Clinica terapeutica, 2011, Volume: 162, Issue:1

    Topics: Adult; Anticonvulsants; Antipsychotic Agents; Benzodiazepines; Clozapine; Combined Modality Therapy; Epilepsy; Fatal Outcome; Female; Haloperidol; Humans; Nordazepam; Olanzapine; Patient Compliance; Psychotherapy; Psychotic Disorders; Schizophrenia, Paranoid; Shared Paranoid Disorder; Sibling Relations; Suicide; Valproic Acid

2011
Pharmacological treatment of deep brain stimulation-induced hypomania leads to clinical remission while preserving motor benefits.
    Neurocase, 2012, Volume: 18, Issue:2

    Topics: Antimanic Agents; Bipolar Disorder; Clozapine; Deep Brain Stimulation; Humans; Male; Middle Aged; Parkinson Disease; Treatment Outcome; Valproic Acid

2012
The effects of neuropsychiatric drugs on glycogen synthase kinase-3 signaling.
    Neuroscience, 2011, Dec-29, Volume: 199

    Topics: Animals; Antidepressive Agents; Antimanic Agents; Antipsychotic Agents; beta Catenin; Blotting, Western; Brain; Clozapine; Fluoxetine; Glycogen Synthase Kinase 3; Haloperidol; Imipramine; Immunoprecipitation; Lithium; Male; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Signal Transduction; Valproic Acid

2011
Persistent febrile illness with multisystem organ failure associated with clozapine.
    Internal medicine journal, 2012, Volume: 42, Issue:1

    Topics: Abdominal Pain; Adult; Antipsychotic Agents; Clozapine; Combined Modality Therapy; Diagnostic Errors; Dibenzothiazepines; Drug Therapy, Combination; Female; Fever; Fluid Therapy; Headache; Hemodiafiltration; Humans; Lithium; Multiple Organ Failure; Norepinephrine; Quetiapine Fumarate; Schizophrenia; Systemic Inflammatory Response Syndrome; Urinary Tract Infections; Valproic Acid; Vasoconstrictor Agents

2012
Valproic acid augmentation in clozapine-associated hand-washing compulsion.
    Psychiatry and clinical neurosciences, 2012, Volume: 66, Issue:5

    Topics: Anticonvulsants; Antipsychotic Agents; Clozapine; Compulsive Behavior; Hand Disinfection; Humans; Male; Middle Aged; Schizophrenia; Valproic Acid

2012
Rapid clozapine dose titration and concomitant sodium valproate increase the risk of myocarditis with clozapine: a case-control study.
    Schizophrenia research, 2012, Volume: 141, Issue:2-3

    Topics: Adolescent; Adult; Age Factors; Aged; Anticonvulsants; Antipsychotic Agents; Area Under Curve; Body Mass Index; Case-Control Studies; Clozapine; Dose-Response Relationship, Drug; Drug Synergism; Female; Humans; Male; Middle Aged; Myocarditis; Retrospective Studies; Schizophrenia; Time Factors; Valproic Acid; Young Adult

2012
Clinical predictors of serum clozapine levels in patients with treatment-resistant schizophrenia.
    International clinical psychopharmacology, 2013, Volume: 28, Issue:1

    Topics: Administration, Oral; Adult; Anticonvulsants; Antipsychotic Agents; Caffeine; Case-Control Studies; Central Nervous System Stimulants; Chi-Square Distribution; Chromatography, High Pressure Liquid; Clozapine; Cross-Sectional Studies; Drug Interactions; Drug Monitoring; Drug Resistance; Female; Food-Drug Interactions; Humans; Least-Squares Analysis; Logistic Models; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Psychiatric Status Rating Scales; Risk Factors; Schizophrenia; Schizophrenic Psychology; Spectrophotometry, Ultraviolet; Treatment Failure; Valproic Acid

2013
Antipsychotic drugs, mood stabilizers, and risk of pneumonia in bipolar disorder: a nationwide case-control study.
    The Journal of clinical psychiatry, 2013, Volume: 74, Issue:1

    Topics: Adolescent; Adult; Anticonvulsants; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Carbamazepine; Case-Control Studies; Clozapine; Cohort Studies; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Evidence-Based Medicine; Female; Hospitalization; Humans; Lithium Carbonate; Male; Middle Aged; Multivariate Analysis; Olanzapine; Pneumonia; Propensity Score; Risk Factors; Taiwan; Valproic Acid; Young Adult

2013
A case report that suggested that aspirin's effects on valproic acid metabolism may contribute to valproic acid's inducer effects on clozapine metabolism.
    Journal of clinical psychopharmacology, 2013, Volume: 33, Issue:6

    Topics: Adult; Antimanic Agents; Antipsychotic Agents; Aspirin; Bipolar Disorder; Clozapine; Dose-Response Relationship, Drug; Drug Interactions; Humans; Male; Valproic Acid

2013
Precursor manic behavior in the assessment and treatment of episodic problem behavior for a woman with a dual diagnosis.
    Journal of applied behavior analysis, 2013,Fall, Volume: 46, Issue:3

    Topics: Antimanic Agents; Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Behavioral Symptoms; Clozapine; Diagnosis, Dual (Psychiatry); Female; Humans; Mental Disorders; Middle Aged; Psychiatric Status Rating Scales; Valproic Acid

2013
Successful treatment of catatonia in a young man with schizophrenia and progressive diffuse cerebral atrophy.
    The Journal of neuropsychiatry and clinical neurosciences, 2014,Winter, Volume: 26, Issue:1

    Topics: Adolescent; Amantadine; Anticonvulsants; Antiparkinson Agents; Antipsychotic Agents; Atrophy; Catatonia; Cerebral Cortex; Clozapine; Drug Therapy, Combination; Humans; Magnetic Resonance Imaging; Male; Memantine; Schizophrenia; Valproic Acid

2014
Valproate reverts zinc and potassium imbalance in schizophrenia-derived reprogrammed cells.
    Schizophrenia research, 2014, Volume: 154, Issue:1-3

    Topics: Antipsychotic Agents; Cell Line; Clozapine; Drug Resistance; Embryonic Stem Cells; Humans; Induced Pluripotent Stem Cells; Neural Stem Cells; Potassium; Schizophrenia; Valproic Acid; Zinc

2014
Can valproic acid be an inducer of clozapine metabolism?
    Pharmacopsychiatry, 2014, Volume: 47, Issue:3

    Topics: Antimanic Agents; Chromatography, High Pressure Liquid; Clozapine; Drug Monitoring; Female; Humans; Linear Models; Male; Mental Disorders; Sex Factors; Smoking; Valproic Acid

2014
Clozapine-related pericarditis during titration phase in a patient with resistant schizophrenia and concomitant valproate treatment: a case report.
    Journal of clinical psychopharmacology, 2014, Volume: 34, Issue:5

    Topics: Adult; Antipsychotic Agents; Clozapine; Drug Resistance; Drug Therapy, Combination; Humans; Indomethacin; Male; Pericarditis; Schizophrenia; Valproic Acid

2014
Skating on thin ice: pragmatic prescribing for medication refractory schizophrenia.
    BMC psychiatry, 2015, Jul-25, Volume: 15

    Topics: Adult; Amisulpride; Antipsychotic Agents; Benzodiazepines; Clozapine; Drug Prescriptions; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Olanzapine; Quetiapine Fumarate; Schizophrenia; Schizophrenic Psychology; Sulpiride; Valproic Acid

2015
Optimizing outcomes in clozapine rechallenge following neutropenia: a cohort analysis.
    The Journal of clinical psychiatry, 2015, Volume: 76, Issue:11

    Topics: Adult; Antimanic Agents; Antipsychotic Agents; Clozapine; Cohort Studies; Drug Therapy, Combination; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukocyte Count; Lithium Compounds; Male; Middle Aged; Neutropenia; Neutrophils; Outcome Assessment, Health Care; Schizophrenia; Valproic Acid; Young Adult

2015
Ibuprofen May Increase Pharmacological Action of Valproate by Displacing It From Plasma Proteins: A Case Report.
    The American journal of psychiatry, 2016, 09-01, Volume: 173, Issue:9

    Topics: Antipsychotic Agents; Blood Proteins; Clozapine; Drug Synergism; Drug Therapy, Combination; Humans; Ibuprofen; Male; Schizophrenia; Valproic Acid; Young Adult

2016
Clozapine-Valproate Adverse Drug Reactions and the Need for a Clozapine Rechallenge Case File.
    The primary care companion for CNS disorders, 2017, Jan-05, Volume: 19, Issue:1

    Topics: Acute Kidney Injury; Antimanic Agents; Antipsychotic Agents; Clozapine; Drug Therapy, Combination; Humans; Male; Middle Aged; Pancreatitis; Psychotic Disorders; Valproic Acid

2017
Sodium valproate and clozapine induced neutropenia: A case control study using register data.
    Schizophrenia research, 2018, Volume: 195

    Topics: Adolescent; Adult; Aged; Antimanic Agents; Antipsychotic Agents; Case-Control Studies; Clozapine; Female; Humans; Male; Middle Aged; Neutropenia; Registries; Valproic Acid; Young Adult

2018
Effect of Valproate and Antidepressant Drugs on Clozapine Metabolism in Patients With Psychotic Mood Disorders.
    Therapeutic drug monitoring, 2018, Volume: 40, Issue:4

    Topics: Adolescent; Adult; Antidepressive Agents; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Clozapine; Drug Interactions; Female; Humans; Male; Middle Aged; Retrospective Studies; Sex Factors; Valproic Acid; Young Adult

2018
Comedication of Valproic Acid Is Associated With Increased Metabolism of Clozapine.
    Journal of clinical psychopharmacology, 2018, Volume: 38, Issue:3

    Topics: Adult; Antimanic Agents; Antipsychotic Agents; Clozapine; Drug Interactions; Drug Monitoring; Female; Humans; Male; Middle Aged; Psychotic Disorders; Retrospective Studies; Valproic Acid

2018
Clozapine toxicity in a CYP2D6 poor metaboliser: Additive effects of haloperidol and valproate on clozapine metabolism.
    Australasian psychiatry : bulletin of Royal Australian and New Zealand College of Psychiatrists, 2018, Volume: 26, Issue:6

    Topics: Adult; Antipsychotic Agents; Clozapine; Cytochrome P-450 CYP2D6; Drug Synergism; Haloperidol; Humans; Male; Schizophrenia; Valproic Acid; Young Adult

2018
Association between electroencephalogram changes and plasma clozapine levels in clozapine-treated patients.
    International clinical psychopharmacology, 2019, Volume: 34, Issue:3

    Topics: Adult; Antipsychotic Agents; Bipolar Disorder; Clozapine; Drug Monitoring; Electroencephalography; Female; Humans; Male; Middle Aged; Retrospective Studies; Schizophrenia; Treatment Outcome; Valproic Acid

2019
Failure of rechallenge clozapine after agranulocytosis: A case report.
    L'Encephale, 2019, Volume: 45, Issue:5

    Topics: Adult; Agranulocytosis; Antipsychotic Agents; Clopenthixol; Clozapine; Drug Resistance; Drug Substitution; Drug Synergism; Drug Therapy, Combination; Humans; Male; Olanzapine; Schizophrenia, Paranoid; Valproic Acid

2019
Reduction in N-Desmethylclozapine Level Is Determined by Daily Dose But Not Serum Concentration of Valproic Acid-Indications of a Presystemic Interaction Mechanism.
    Therapeutic drug monitoring, 2019, Volume: 41, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Clozapine; Drug Interactions; Drug Monitoring; Female; Humans; Male; Middle Aged; Retrospective Studies; Valproic Acid; Young Adult

2019
A comparative study of detection of myocarditis induced by clozapine: With and without cardiac monitoring.
    Psychiatry research, 2019, Volume: 279

    Topics: Adult; Antipsychotic Agents; Clozapine; Drug Therapy, Combination; Female; Humans; Incidence; Inpatients; Lithium; Male; Middle Aged; Monitoring, Physiologic; Myocarditis; Psychotic Disorders; Risk Factors; Valproic Acid; Young Adult

2019
Future Studies on the Interaction Between Clozapine and Valproic Acid Should Aspire to Include Longitudinal Designs and Free Valproate Concentrations, and Should Consider that Inducer and/or Inhibitory Effects May Vary With Time, the Individual, and the A
    Therapeutic drug monitoring, 2020, Volume: 42, Issue:1

    Topics: Clozapine; Cytochrome P-450 Enzyme Inducers; Humans; Valproic Acid

2020
Clozapine-induced myocarditis during co-administration of valproate: A case report.
    Psychiatria polska, 2019, Oct-30, Volume: 53, Issue:5

    Topics: Antipsychotic Agents; Clozapine; Drug Therapy, Combination; Humans; Male; Myocarditis; Schizophrenia; Valproic Acid; Young Adult

2019
Activation of Astroglial Connexin is Involved in Concentration-Dependent Double-Edged Sword Clinical Action of Clozapine.
    Cells, 2020, 02-11, Volume: 9, Issue:2

    Topics: Antipsychotic Agents; Astrocytes; Cell Membrane; Clozapine; Connexin 43; Glutamic Acid; Humans; Myocarditis; Schizophrenia; Serine; Valproic Acid

2020
Effect of venlafaxine dosage, valproic acid concentration, sex, and age on steady state dose-corrected concentrations of venlafaxine and O-desmethylvenlafaxine: A retrospective analysis of therapeutic drug monitoring data in a Chinese population.
    Human psychopharmacology, 2020, Volume: 35, Issue:3

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Asian People; Clozapine; Desvenlafaxine Succinate; Drug Interactions; Drug Monitoring; Female; Humans; Male; Middle Aged; Polypharmacy; Retrospective Studies; Sex Factors; Valproic Acid; Venlafaxine Hydrochloride; Young Adult

2020
[Thoughts on a favourable evolution of a COVID-19 in a patient with resistant schizophrenia and on a combination of clozapine and paliperidone palmitate].
    L'Encephale, 2020, Volume: 46, Issue:3S

    Topics: Anticonvulsants; Antipsychotic Agents; Betacoronavirus; Clozapine; Coronavirus Infections; COVID-19; Delayed-Action Preparations; Drug Resistance; Drug Therapy, Combination; Humans; Immunologic Factors; Lithium Carbonate; Male; Middle Aged; Paliperidone Palmitate; Pandemics; Pneumonia, Viral; Psychotic Disorders; SARS-CoV-2; Sialorrhea; Treatment Outcome; Valproic Acid

2020
An International Adult Guideline for Making Clozapine Titration Safer by Using Six Ancestry-Based Personalized Dosing Titrations, CRP, and Clozapine Levels.
    Pharmacopsychiatry, 2022, Volume: 55, Issue:2

    Topics: Adult; Antipsychotic Agents; Asian People; C-Reactive Protein; Clozapine; Female; Humans; Male; Valproic Acid

2022
Four cases of myocarditis in US hospitals possibly associated with clozapine poor metabolism and a comparison with prior published cases.
    Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology, 2022, 03-01, Volume: 24, Issue:1

    Topics: Antipsychotic Agents; Clozapine; Hospitals; Humans; Male; Myocarditis; Obesity; Schizophrenia; Valproic Acid

2022
Pharmacokinetic interactions between clozapine and valproic acid in patients with treatment-resistant schizophrenia: Does UGT polymorphism affect these drug interactions?
    Chemico-biological interactions, 2022, Sep-01, Volume: 364

    Topics: Albumins; Antipsychotic Agents; Chromatography, Liquid; Clozapine; Cytochrome P-450 CYP2C19; Drug Interactions; Glucuronosyltransferase; Humans; Schizophrenia; Schizophrenia, Treatment-Resistant; Tandem Mass Spectrometry; Valproic Acid

2022
Confusion, Rigidity, and Elevated Creatine Phosphokinase: Atypical Neuroleptic Malignant Syndrome Possibly Associated With Clozapine and Sodium Valproate Use.
    The primary care companion for CNS disorders, 2022, 09-29, Volume: 24, Issue:5

    Topics: Antipsychotic Agents; Clozapine; Creatine Kinase; Humans; Neuroleptic Malignant Syndrome; Valproic Acid

2022
Valproate-related neutropenia and lithium-related leukocytosis in patients treated with clozapine: a retrospective cohort study.
    BMC psychiatry, 2023, 03-15, Volume: 23, Issue:1

    Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Humans; Leukocytosis; Lithium; Male; Neutropenia; Retrospective Studies; Valproic Acid

2023
Effect of smoking habits and concomitant valproic acid use on relapse in patients with treatment-resistant schizophrenia receiving clozapine: A 1-year retrospective cohort study.
    Acta psychiatrica Scandinavica, 2023, Volume: 148, Issue:5

    Topics: Antipsychotic Agents; Clozapine; Habits; Humans; Retrospective Studies; Schizophrenia; Schizophrenia, Treatment-Resistant; Smoking; Valproic Acid

2023
Association of clozapine and norclozapine levels with patient and therapy characteristics-focus on interaction with valproic acid.
    European journal of clinical pharmacology, 2023, Volume: 79, Issue:11

    Topics: Clozapine; Humans; Mental Disorders; Retrospective Studies; Valproic Acid

2023