valproic acid has been researched along with calpain in 3 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Crosland, MB; Nosek, TM | 1 |
| Hu, JP; Teng, WP; Wang, CY; Wang, SL; Wang, T; Wang, X; Wang, ZY; Xie, JW | 1 |
| Aurelian, L; Balan, I; Bollino, D | 1 |
3 other study(ies) available for valproic acid and calpain
| Article | Year |
|---|---|
Calcium-dependent proteolysis in neural tissue is activated at physiologic intracellular Ca2+ levels and inhibited by some anticonvulsants.
Topics: Animals; Anticonvulsants; Astacoidea; Brain; Calcium; Calpain; Caprylates; Endopeptidases; Pentobarbital; Phenytoin; Protease Inhibitors; Spinal Cord; Valproic Acid | 1983 |
Valproate reduces tau phosphorylation via cyclin-dependent kinase 5 and glycogen synthase kinase 3 signaling pathways.
Topics: Amyloid beta-Protein Precursor; Animals; Brain; Calpain; Cell Line, Tumor; Cyclin-Dependent Kinase 5; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Humans; Mice; Mice, Transgenic; Neuroblastoma; Phosphorylation; Presenilin-1; Signal Transduction; tau Proteins; Threonine; Valproic Acid | 2011 |
Valproic acid induces neuronal cell death through a novel calpain-dependent necroptosis pathway.
Topics: Animals; Apoptosis; Calpain; Cell Death; Cell Line; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation; Humans; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 8; Mucolipidoses; Necrosis; Nerve Growth Factor; Neurons; PC12 Cells; Protein Serine-Threonine Kinases; Rats; Receptor-Interacting Protein Serine-Threonine Kinases; Signal Transduction; Time Factors; Valproic Acid | 2015 |