valproic acid has been researched along with butyric acid in 36 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (2.78) | 18.7374 |
| 1990's | 3 (8.33) | 18.2507 |
| 2000's | 5 (13.89) | 29.6817 |
| 2010's | 21 (58.33) | 24.3611 |
| 2020's | 6 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Amano, O; Izeki, S; Kido, Y; Ogihara, T; Ono, A; Sai, Y; Satoh, E; Takanaga, H; Tamai, I; Tsuji, A; Yabuuchi, H | 1 |
| Strassburg, CP; Tukey, RH | 1 |
| Bora-Tatar, G; Dalkara, S; Dayangaç-Erden, D; Demir, AS; Erdem-Yurter, H; Yelekçi, K | 1 |
| Fass, DM; Ghosh, B; Haggarty, SJ; Hennig, K; Klein, PS; Lewis, TA; Maglathlin, RL; Mazitschek, R; Norton, S; Reis, SA; Shah, R; Zhao, WN | 1 |
| Alfano, AI; Barone, S; Brindisi, M; Cassese, E; Summa, V | 1 |
| Dawson, DA | 1 |
| Brown, NA; Clarke, DO | 1 |
| Blau, CA; Dover, G; Fournarakis, B; Josephson, B; Li, Q; Liakopoulou, E; Papayannopoulou, T; Raisys, V; Stamatoyannopoulos, G; Wolf, JA | 1 |
| Schroeder, TM; Westendorf, JJ | 1 |
| Chen, JF; Heidmets, LT; Kalda, A; Shen, HY; Zharkovsky, A | 1 |
| Chen, JF; Ferrara, J; Kalda, A; Shen, HY; Yu, L; Zhu, J | 1 |
| Kidd, SK; Schneider, JS | 1 |
| Correia, AO; da Graça Naffah-Mazzacorati, M; de Castro Brito, GA; de Oliveira Gonçalves, D; Félix, FH; Leal, LK; Neves, KR; Santos Cerqueira, G; Siqueira, RM; Viana, GS; Ximenes, JC | 1 |
| Bondarev, GN; Filatov, MV; Ibatulin, FM; Kovalëv, RA; Stam, TA | 1 |
| Fujiki, R; Fujitani, M; Sato, A; Yamashita, T | 1 |
| Liu, Q; Ma, N; Ma, Y; Zhang, L | 1 |
| Carter, P; Fowler, JS; Hooker, JM; Kim, SW; King, P; Muench, L; Otto, N; Reid, AE; Shea, C; Volkow, ND; Win, K | 1 |
| Heinrichs, SC; Kaplan, GB; Leite-Morris, KA; Rasmusson, AM | 1 |
| de Theije, CG; Garssen, J; Knol, J; Kraneveld, AD; Lambert, J; Oozeer, R; Ramadan, M; van Eijndthoven, T; Wopereis, H | 1 |
| Bhatia, HS; de Oliveira, AC; Fiebich, BL; Kumar, A; Singh, V | 1 |
| Ago, Y; Hara, Y; Hashimoto, H; Hayata-Takano, A; Kataoka, S; Kawanai, T; Maeda, Y; Matsuda, T; Takano, E; Takuma, K; Watanabe, R | 1 |
| Gonçalves, CL; Lopes-Borges, J; Quevedo, J; Streck, EL; Tonin, PT; Valvassori, SS; Varela, RB; Vieira, JS | 1 |
| Amboni, RT; Bianchini, G; Dal-Pont, GC; Lopes-Borges, J; Mariot, E; Quevedo, J; Valvassori, SS; Varela, RB | 1 |
| Chandra, R; Kalsan, M; Kumar, N; Saini, A; Singh, VK | 1 |
| Jain, N; Kaki, SS; Rao, BB; Reddy, YS; Vijayalakshmi, P | 1 |
| Gean, PW; Hsiao, YH; Su, CL; Su, CW | 1 |
| Doll, M; Hrgovic, I; Kaufmann, R; Kippenberger, S; Meissner, M; Pinter, A | 1 |
| Mahadevan, V; P, HA; R, M | 1 |
| Aschner, M; Johnson, J; Lee, E; Pajarillo, EAB; Reams, R; Son, DS; Taka, E | 1 |
| Yamato, E | 1 |
| Cremaschi, GA; Dagrosa, MA; Juvenal, GJ; Perona, M; Pisarev, MA; Rodriguez, C; Rosemblit, C; Rossich, L; Thomasz, L | 1 |
| Amodio, N; Calignano, A; Citraro, R; De Caro, C; De Sarro, G; Gallo Cantafio, ME; Lama, A; Leo, A; Mattace Raso, G; Nesci, V; Russo, E; Russo, R; Tallarico, M | 1 |
| Annunziata, C; Calignano, A; Cavaliere, G; Citraro, R; De Caro, C; De Sarro, G; Ferrante, MC; Iannone, M; Lama, A; Mattace Raso, G; Meli, R; Mollica, MP; Pirozzi, C; Russo, E; Tallarico, M | 1 |
| Dal-Pont, GC; Gava, FF; Quevedo, J; Resende, WR; Tye, SJ; Valvassori, SS; Varela, RB | 1 |
| Chen, W; Kong, Q; Li, X; Tian, P; Wang, B; Wang, G; Zhang, H; Zhao, J | 1 |
| Marchant, JS; Moradi, H; Subramanian, VS; Teafatiller, T | 1 |
3 review(s) available for valproic acid and butyric acid
| Article | Year |
|---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic | 2000 |
Chasing a Breath of Fresh Air in Cystic Fibrosis (CF): Therapeutic Potential of Selective HDAC6 Inhibitors to Tackle Multiple Pathways in CF Pathophysiology.
Topics: Animals; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Histone Deacetylase 6; Humans; Signal Transduction | 2022 |
Mechanism of Induction: Induced Pluripotent Stem Cells (iPSCs).
Topics: Ascorbic Acid; Butyric Acid; Cell Differentiation; Cellular Reprogramming; Gene Expression; Humans; Induced Pluripotent Stem Cells; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Nuclear Transfer Techniques; Octamer Transcription Factor-3; Proto-Oncogene Proteins c-myc; Pyridines; Pyrimidines; Regenerative Medicine; SOXB1 Transcription Factors; Transgenes; Valproic Acid | 2015 |
33 other study(ies) available for valproic acid and butyric acid
| Article | Year |
|---|---|
Immunohistochemical and functional characterization of pH-dependent intestinal absorption of weak organic acids by the monocarboxylic acid transporter MCT1.
Topics: Amino Acid Sequence; Animals; Benzoic Acid; Biological Transport; Carboxylic Acids; Carrier Proteins; Cell Line; Digestive System; Hydrogen-Ion Concentration; Immunohistochemistry; Intestinal Absorption; Lactic Acid; Molecular Sequence Data; Monocarboxylic Acid Transporters; Rats; Tissue Distribution; Transfection | 1999 |
Molecular modifications on carboxylic acid derivatives as potent histone deacetylase inhibitors: Activity and docking studies.
Topics: Caffeic Acids; Carboxylic Acids; Catalytic Domain; Chlorogenic Acid; Curcumin; Enzyme Inhibitors; HeLa Cells; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Models, Molecular; Molecular Structure; Protein Binding | 2009 |
Effect of Inhibiting Histone Deacetylase with Short-Chain Carboxylic Acids and Their Hydroxamic Acid Analogs on Vertebrate Development and Neuronal Chromatin.
Topics: | 2010 |
Additive incidence of developmental malformation for Xenopus embryos exposed to a mixture of ten aliphatic carboxylic acids.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Butyrates; Butyric Acid; Caproates; Caprylates; Carboxylic Acids; Drug Synergism; Embryo, Nonmammalian; Heptanoic Acids; Pentanoic Acids; Propionates; Structure-Activity Relationship; Valproic Acid; Xenopus | 1991 |
Valproic acid teratogenesis and embryonic lipid metabolism.
Topics: Animals; Butyrates; Butyric Acid; Embryo, Mammalian; In Vitro Techniques; Lipids; Lovastatin; Naphthalenes; Rats; Rats, Inbred F344; Teratogens; Valproic Acid | 1987 |
Stimulation of fetal hemoglobin production by short chain fatty acids.
Topics: Adult; Anemia, Sickle Cell; Animals; Anticonvulsants; Butyrates; Butyric Acid; Cells, Cultured; Epilepsy; Erythroid Precursor Cells; Erythropoietin; Fatty Acids, Volatile; Fetal Hemoglobin; Gene Expression Regulation; Globins; Hemoglobinopathies; Humans; Papio; Pentanoic Acids; Propionates; Reticulocytes; RNA, Messenger; Structure-Activity Relationship; Valproic Acid | 1995 |
Histone deacetylase inhibitors promote osteoblast maturation.
Topics: Acetylation; Alkaline Phosphatase; Animals; Benzamides; Butyric Acid; Calcification, Physiologic; Calcium; Cell Cycle; Cell Differentiation; Cell Line; Cell Shape; Cell Survival; Cells, Cultured; Collagen Type I; Core Binding Factor Alpha 1 Subunit; Enzyme Inhibitors; Gene Expression; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Hydroxamic Acids; Integrin-Binding Sialoprotein; Mice; Organ Culture Techniques; Osteoblasts; Osteocalcin; Osteopontin; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; Sialoglycoproteins; Skull; Valproic Acid | 2005 |
Histone deacetylase inhibitors modulates the induction and expression of amphetamine-induced behavioral sensitization partially through an associated learning of the environment in mice.
Topics: Amphetamine; Animals; Association Learning; Behavior, Animal; Butyric Acid; Central Nervous System Stimulants; Drug Interactions; Environment; Enzyme Inhibitors; Histones; Male; Mice; Mice, Inbred C57BL; Motor Activity; Time Factors; Valproic Acid | 2007 |
Additive effects of histone deacetylase inhibitors and amphetamine on histone H4 acetylation, cAMP responsive element binding protein phosphorylation and DeltaFosB expression in the striatum and locomotor sensitization in mice.
Topics: Acetylation; Amphetamine; Animals; Butyric Acid; Central Nervous System Stimulants; Chromatin Immunoprecipitation; Corpus Striatum; CREB-Binding Protein; Drug Interactions; Enzyme Inhibitors; Gene Expression; Histones; Male; Mice; Mice, Inbred C57BL; Motor Activity; Phosphorylation; Proto-Oncogene Proteins c-fos; Time Factors; Valproic Acid | 2008 |
Protection of dopaminergic cells from MPP+-mediated toxicity by histone deacetylase inhibition.
Topics: 1-Methyl-4-phenylpyridinium; Acetylation; Analysis of Variance; Animals; Apoptosis; Butyric Acid; Cell Line; Cells, Cultured; Dopamine; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Immunohistochemistry; Nerve Degeneration; Neurons; Rats; Valproic Acid; Vorinostat | 2010 |
Valproic acid: an anticonvulsant drug with potent antinociceptive and anti-inflammatory properties.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Anticonvulsants; Butyric Acid; Carrageenan; Drug Synergism; Edema; Foot; Formaldehyde; Hot Temperature; Hydroxamic Acids; Leukocyte Count; Male; Mice; Pain; Pentoxifylline; Peritonitis; Peroxidase; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha; Valproic Acid; Vorinostat | 2013 |
[Possibilities of epigenetic anti-tumor therapy in in-vitro models].
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Butyric Acid; Cell Line, Tumor; Cell Proliferation; Cisplatin; Deoxycytidine; Dose-Response Relationship, Drug; Drug Synergism; Epigenesis, Genetic; Gemcitabine; Histone Deacetylase Inhibitors; Humans; Neoplasms; Radiotherapy, Adjuvant; Salts; Sodium; Time Factors; Valproic Acid | 2012 |
A proapoptotic effect of valproic acid on progenitors of embryonic stem cell-derived glutamatergic neurons.
Topics: Acetylation; Animals; Anticonvulsants; Apoptosis; Butyric Acid; Cell Line; Cells, Cultured; Embryonic Stem Cells; Histone Deacetylase Inhibitors; Histones; Hydroxamic Acids; Mice; Neural Stem Cells; Neurons; Protein Processing, Post-Translational; Valproic Acid | 2013 |
Genome-wide screening for genes associated with valproic acid sensitivity in fission yeast.
Topics: Acetylation; Biological Transport; Butyric Acid; Calcium; Calcium Channels; Cell Cycle Proteins; Cell Membrane; Cytoplasm; Drug Resistance, Fungal; Genes, Fungal; Genome-Wide Association Study; Histone Deacetylase Inhibitors; Histones; Membrane Glycoproteins; Mutation; Proteins; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Signal Transduction; Transcriptional Activation; Valproic Acid | 2013 |
Whole-body pharmacokinetics of HDAC inhibitor drugs, butyric acid, valproic acid and 4-phenylbutyric acid measured with carbon-11 labeled analogs by PET.
Topics: Animals; Blood Proteins; Brain; Butyric Acid; Carbon Radioisotopes; Female; Histone Deacetylase Inhibitors; Isotope Labeling; Papio; Phenylbutyrates; Positron-Emission Tomography; Radiochemistry; Tissue Distribution; Valproic Acid | 2013 |
Repeated valproate treatment facilitates fear extinction under specific stimulus conditions.
Topics: Animals; Butyric Acid; Conditioning, Classical; Extinction, Psychological; Fear; Histone Deacetylase Inhibitors; Male; Mice; Time Factors; Valproic Acid | 2013 |
Altered gut microbiota and activity in a murine model of autism spectrum disorders.
Topics: Acetic Acid; Animals; Butyric Acid; Child Development Disorders, Pervasive; Disease Models, Animal; Female; Intestine, Large; Lactic Acid; Male; Mice; Mice, Inbred BALB C; Microbiota; Sex Factors; Valproic Acid | 2014 |
Histone deacetylase inhibitors valproic acid and sodium butyrate enhance prostaglandins release in lipopolysaccharide-activated primary microglia.
Topics: Animals; Butyric Acid; Cells, Cultured; Histone Deacetylase Inhibitors; Lipopolysaccharides; Microglia; Prostaglandins; Rats; Rats, Wistar; Valproic Acid | 2014 |
Chronic treatment with valproic acid or sodium butyrate attenuates novel object recognition deficits and hippocampal dendritic spine loss in a mouse model of autism.
Topics: Acetylation; Animals; Autistic Disorder; Butyric Acid; CA1 Region, Hippocampal; Dendritic Spines; Disease Models, Animal; Exploratory Behavior; Female; Histone Deacetylase Inhibitors; Histones; Male; Mice; Pregnancy; Prenatal Exposure Delayed Effects; Valproic Acid | 2014 |
Histone deacetylase inhibitors reverse manic-like behaviors and protect the rat brain from energetic metabolic alterations induced by ouabain.
Topics: Animals; Antimanic Agents; Behavior, Animal; Bipolar Disorder; Brain; Butyric Acid; Citric Acid Cycle; Disease Models, Animal; Energy Metabolism; Exploratory Behavior; Histone Deacetylase Inhibitors; Lithium; Male; Motor Activity; Ouabain; Rats; Rats, Wistar; Valproic Acid | 2015 |
Sodium butyrate and mood stabilizers block ouabain-induced hyperlocomotion and increase BDNF, NGF and GDNF levels in brain of Wistar rats.
Topics: Affect; Animals; Antimanic Agents; Bipolar Disorder; Brain-Derived Neurotrophic Factor; Butyric Acid; Disease Models, Animal; Glial Cell Line-Derived Neurotrophic Factor; Hippocampus; Histamine Antagonists; Lithium Compounds; Locomotion; Male; Motor Activity; Nerve Growth Factor; Ouabain; Prefrontal Cortex; Rats; Rats, Wistar; Treatment Outcome; Valproic Acid | 2015 |
Study on Synthesis, Characterization and Antiproliferative Activity of Novel Diisopropylphenyl Esters of Selected Fatty Acids.
Topics: alpha-Linolenic Acid; Antineoplastic Agents; Butyric Acid; Caproates; Cell Proliferation; Esterification; Esters; HeLa Cells; Hep G2 Cells; Humans; Propofol; Valproic Acid | 2016 |
Epigenetic regulation of BDNF in the learned helplessness-induced animal model of depression.
Topics: Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Butyric Acid; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Epigenesis, Genetic; Exons; Helplessness, Learned; Hindlimb Suspension; Hippocampus; Histone Deacetylase Inhibitors; Histone Deacetylases; Imipramine; Male; Mice; Mice, Inbred C57BL; RNA, Small Interfering; Swimming; Valproic Acid | 2016 |
Histone deacetylase inhibitors interfere with angiogenesis by decreasing endothelial VEGFR-2 protein half-life in part via a VE-cadherin-dependent mechanism.
Topics: Antigens, CD; Butyric Acid; Cadherins; Endothelium; Gene Expression; Gene Knockdown Techniques; Half-Life; Histone Deacetylase 1; Histone Deacetylase 6; Histone Deacetylase Inhibitors; Histone Deacetylases; Human Umbilical Vein Endothelial Cells; Humans; Hydroxamic Acids; Neovascularization, Physiologic; Repressor Proteins; RNA, Messenger; RNA, Small Interfering; Valproic Acid; Vascular Endothelial Growth Factor Receptor-2 | 2017 |
HDAC inhibitors show differential epigenetic regulation and cell survival strategies on p53 mutant colon cancer cells.
Topics: Benzamides; Butyric Acid; Cell Survival; Colonic Neoplasms; Computer Simulation; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; HCT116 Cells; Histone Deacetylase Inhibitors; Humans; Mutation; Pyridines; Tumor Suppressor Protein p53; Valproic Acid | 2018 |
Valproate and sodium butyrate attenuate manganese-decreased locomotor activity and astrocytic glutamate transporters expression in mice.
Topics: Animals; Astrocytes; Butyric Acid; Cerebellum; Cerebral Cortex; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Male; Manganese; Mice, Inbred C57BL; Motor Activity; Neuroprotective Agents; Rotarod Performance Test; Valproic Acid | 2018 |
High dose of histone deacetylase inhibitors affects insulin secretory mechanism of pancreatic beta cell line.
Topics: Animals; Butyric Acid; Cattle; Cell Line; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Insulin; Insulin-Secreting Cells; Valproic Acid | 2018 |
Radiosensitivity enhancement of human thyroid carcinoma cells by the inhibitors of histone deacetylase sodium butyrate and valproic acid.
Topics: Butyric Acid; Cell Cycle Checkpoints; Cell Death; Cell Line, Tumor; DNA Damage; DNA Repair Enzymes; Gamma Rays; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Histones; Humans; Radiation Tolerance; Thyroid Neoplasms; Valproic Acid | 2018 |
Effects of Histone Deacetylase Inhibitors on the Development of Epilepsy and Psychiatric Comorbidity in WAG/Rij Rats.
Topics: Acetylation; Action Potentials; Animals; Avoidance Learning; Behavior, Animal; Butyric Acid; Comorbidity; Epilepsy; Histone Deacetylase Inhibitors; Histones; Male; Rats, Wistar; Valproic Acid | 2020 |
Butyrate prevents valproate-induced liver injury: In vitro and in vivo evidence.
Topics: Anticonvulsants; Butyric Acid; Chemical and Drug Induced Liver Injury; Chemical and Drug Induced Liver Injury, Chronic; Hep G2 Cells; Hepatocytes; Humans; Lipid Metabolism; Mitochondria; Oxidation-Reduction; Oxidative Stress; Valproic Acid | 2020 |
HDAC inhibitors reverse mania-like behavior and modulate epigenetic regulatory enzymes in an animal model of mania induced by Ouabain.
Topics: Animals; Behavior, Animal; Bipolar Disorder; Butyric Acid; Corpus Striatum; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferases; Frontal Lobe; Hippocampus; Histone Acetyltransferases; Histone Deacetylase Inhibitors; Histone Deacetylases; Locomotion; Male; Mania; Ouabain; Rats; Rats, Wistar; Signal Transduction; Treatment Outcome; Valproic Acid | 2020 |
Daily intake of Lactobacillus alleviates autistic-like behaviors by ameliorating the 5-hydroxytryptamine metabolic disorder in VPA-treated rats during weaning and sexual maturation.
Topics: Animals; Autistic Disorder; Behavior, Animal; Butyric Acid; Disease Models, Animal; Fatty Acids, Volatile; Gastrointestinal Microbiome; Lactobacillus; Probiotics; Rats; Serotonin; Sexual Maturation; Tryptophan; Valproic Acid; Weaning | 2021 |
Histone deacetylase inhibitors regulate vitamin C transporter functional expression in intestinal epithelial cells.
Topics: Acetylation; Animals; Ascorbic Acid; Butyric Acid; Caco-2 Cells; Epigenesis, Genetic; Epithelial Cells; Histone Deacetylase Inhibitors; Humans; Intestinal Mucosa; Jejunum; Mice; Mice, Inbred BALB C; Promoter Regions, Genetic; RNA, Small Interfering; Sodium-Coupled Vitamin C Transporters; Valproic Acid | 2021 |