valproic acid and bupropion

valproic acid has been researched along with bupropion in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19902 (8.70)18.7374
1990's5 (21.74)18.2507
2000's6 (26.09)29.6817
2010's10 (43.48)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Glen, RC; Lowe, R; Mitchell, JB1
Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Villeneuve, A1
Hudson, JI; Pope, HG1
Lerer, B1
Jefferson, JW1
Callahan, AM; Chao, J; George, MS; Hinton, ML; Jenkins, JB; Ketter, TA; Marangell, LB; Pazzaglia, PJ; Post, RM; Schroeder, DH1
Leibenluft, E1
Behar, D; Schaller, JL1
Demers, MF; Filteau, MJ; Leblanc, J; Lefrançoise, S1
Hume, JH; Kowatch, RA; Kromelis, M; Sethuraman, G; Weinberg, WA1
Jaffe, R; Leavitt, R; Wind, T1
Howland, RH1
Alda, M; Beaulieu, S; Berk, M; Bond, DJ; Calabrese, JR; Frey, BN; Goldstein, BI; Kanba, S; Kapczinski, F; Kennedy, SH; Kozicky, J; Lafer, B; Lam, RW; MacQueen, G; Malhi, G; McIntosh, D; McIntyre, RS; Milev, RV; O'Donovan, C; Parikh, SV; Post, RM; Ravindran, A; Rej, S; Schaffer, A; Sharma, V; Suppes, T; Vazquez, G; Vieta, E; Yatham, LN1

Reviews

4 review(s) available for valproic acid and bupropion

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Antidepressant drug therapy for bulimia: current status.
    The Journal of clinical psychiatry, 1986, Volume: 47, Issue:7

    Topics: Antidepressive Agents; Bupropion; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Feeding and Eating Disorders; Fenfluramine; Humans; Hyperphagia; Lithium; Lithium Carbonate; Methamphetamine; Monoamine Oxidase Inhibitors; Nomifensine; Phenytoin; Placebos; Propiophenones; Valproic Acid

1986
Alternative therapies for bipolar disorder.
    The Journal of clinical psychiatry, 1985, Volume: 46, Issue:8

    Topics: Ascorbic Acid; Bipolar Disorder; Bupropion; Carbamazepine; Choline; Clonazepam; Clonidine; Clorgyline; Demeclocycline; Fenfluramine; Humans; Methylene Blue; Phosphatidylcholines; Physostigmine; Propiophenones; Propranolol; Spironolactone; Thyroxine; Tryptophan; Valproic Acid

1985
Issues in the treatment of women with bipolar illness.
    The Journal of clinical psychiatry, 1997, Volume: 58 Suppl 15

    Topics: Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Bipolar Disorder; Bupropion; Depression, Postpartum; Female; Humans; Male; Monoamine Oxidase Inhibitors; Pregnancy; Prevalence; Reproduction; Selective Serotonin Reuptake Inhibitors; Sex Factors; Valproic Acid

1997

Trials

3 trial(s) available for valproic acid and bupropion

ArticleYear
Antidepressant drug therapy for bulimia: current status.
    The Journal of clinical psychiatry, 1986, Volume: 47, Issue:7

    Topics: Antidepressive Agents; Bupropion; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Feeding and Eating Disorders; Fenfluramine; Humans; Hyperphagia; Lithium; Lithium Carbonate; Methamphetamine; Monoamine Oxidase Inhibitors; Nomifensine; Phenytoin; Placebos; Propiophenones; Valproic Acid

1986
Carbamazepine but not valproate induces bupropion metabolism.
    Journal of clinical psychopharmacology, 1995, Volume: 15, Issue:5

    Topics: Adult; Antidepressive Agents; Biotransformation; Bipolar Disorder; Bupropion; Carbamazepine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Depressive Disorder; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Enzyme Induction; Humans; Liver; Metabolic Clearance Rate; Middle Aged; Mixed Function Oxygenases; Treatment Outcome; Valproic Acid

1995
Combination pharmacotherapy in children and adolescents with bipolar disorder.
    Biological psychiatry, 2003, Jun-01, Volume: 53, Issue:11

    Topics: Adolescent; Antidepressive Agents; Antimanic Agents; Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Bipolar Disorder; Bupropion; Carbamazepine; Central Nervous System Stimulants; Child; Drug Therapy, Combination; Female; Humans; Lithium; Male; Methylphenidate; Prospective Studies; Risperidone; Selective Serotonin Reuptake Inhibitors; Valproic Acid

2003

Other Studies

17 other study(ies) available for valproic acid and bupropion

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
    Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24

    Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
[Duration of antidepressive treatments].
    L'Encephale, 1992, Volume: 18 Spec No 4

    Topics: Antidepressive Agents, Tricyclic; Bupropion; Carbamazepine; Depressive Disorder; Dose-Response Relationship, Drug; Humans; Lithium; Monoamine Oxidase Inhibitors; Serotonin Antagonists; Valproic Acid

1992
Psychotropic medications and their effects on sexual function.
    The Journal of clinical psychiatry, 1995, Volume: 56, Issue:11

    Topics: Bupropion; Epilepsy; Female; Humans; Male; Psychotropic Drugs; Selective Serotonin Reuptake Inhibitors; Sexual Behavior; Sexual Dysfunctions, Psychological; Testosterone; Valproic Acid

1995
Treatment of a case of comorbid bipolar disorder and attention-deficit/hyperactivity disorder.
    The Journal of neuropsychiatry and clinical neurosciences, 1998,Spring, Volume: 10, Issue:2

    Topics: Adult; Antidepressive Agents, Second-Generation; Antimanic Agents; Attention Deficit Disorder with Hyperactivity; Bipolar Disorder; Bupropion; Central Nervous System Stimulants; Dextroamphetamine; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Valproic Acid

1998
Visual and auditory hallucinations with the association of bupropion and valproate.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 2000, Volume: 45, Issue:2

    Topics: Anticonvulsants; Antidepressive Agents; Bipolar Disorder; Bupropion; Hallucinations; Humans; Male; Middle Aged; Valproic Acid

2000
QTc prolongation in multiple drug overdose.
    Journal of clinical psychopharmacology, 2004, Volume: 24, Issue:3

    Topics: Adult; Bupropion; Drug Overdose; Fluoxetine; Humans; Long QT Syndrome; Male; Piperazines; Psychotic Disorders; Thiazoles; Valproic Acid

2004
Psychopharmacology news. New side effects of agents.
    Journal of child and adolescent psychopharmacology, 2007, Volume: 17, Issue:3

    Topics: Benzodiazepines; Bupropion; Female; Humans; Olanzapine; Pregnancy; Propranolol; Psychotropic Drugs; Valproic Acid

2007
When is a "generic" medication not really a generic?
    Journal of psychosocial nursing and mental health services, 2010, Volume: 48, Issue:2

    Topics: Bupropion; Cyclohexanols; Drug Costs; Drug Labeling; Drug Prescriptions; Drugs, Generic; Humans; Marketing of Health Services; Paroxetine; Patient Selection; Psychiatric Nursing; Psychotropic Drugs; Therapeutic Equivalency; United States; United States Food and Drug Administration; Valproic Acid; Venlafaxine Hydrochloride

2010
Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) 2018 guidelines for the management of patients with bipolar disorder.
    Bipolar disorders, 2018, Volume: 20, Issue:2

    Topics: Adolescent; Aged; Algorithms; Antipsychotic Agents; Bipolar Disorder; Bupropion; Child; Evidence-Based Medicine; Female; Humans; Lamotrigine; Lithium Compounds; Olanzapine; Quetiapine Fumarate; Societies, Medical; Suicide; Suicide Prevention; Valproic Acid

2018