valproic acid has been researched along with betaine in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (16.67) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 8 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Jones, LH; Nadanaciva, S; Rana, P; Will, Y | 1 |
| Bock, I; Melegh, B; Pap, M; Rebouche, CJ | 1 |
| Bock, I; Cseko, J; Farkas, V; Sandor, A | 1 |
| Bröer, A; Bröer, S; Kaltenbach, S; Lang, F; Lükewille, U; Moschen, I; Risler, T; Wagner, CA | 1 |
| Donzelli, M; Fischer-Barnicol, D; Krähenbühl, S; Morand, R; Mullen, PJ; Todesco, L | 1 |
| Chen, X; Chen, Z; Cui, C; Huang, F; Jiang, X; Niu, J; Sun, J | 1 |
1 review(s) available for valproic acid and betaine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
11 other study(ies) available for valproic acid and betaine
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone | 2016 |
Relationship of carnitine and carnitine precursors lysine, epsilon-N-trimethyllysine, and gamma-butyrobetaine in drug-induced carnitine depletion.
Topics: Adolescent; Bacteriuria; Betaine; Carnitine; Child; Child, Preschool; Creatinine; Epilepsy; Female; Humans; Lysine; Male; Pivampicillin; Urinary Tract Infections; Valproic Acid | 1993 |
Inhibition of carnitine biosynthesis by valproic acid in rats--the biochemical mechanism of inhibition.
Topics: Acetyl Coenzyme A; Animals; Anticonvulsants; Betaine; Carnitine; Coenzyme A; Glutamic Acid; Humans; Ketoglutaric Acids; Liver; Male; Rats; Rats, Wistar; Valproic Acid | 1996 |
Functional and pharmacological characterization of human Na(+)-carnitine cotransporter hOCTN2.
Topics: Amino Acids; Animals; Betaine; Biological Transport; Carnitine; Carrier Proteins; Emetine; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Lipotropic Agents; Membrane Potentials; Membrane Proteins; Microinjections; Oocytes; Organic Cation Transport Proteins; Patch-Clamp Techniques; Pentanoic Acids; Protein Synthesis Inhibitors; RNA, Complementary; Sodium; Solute Carrier Family 22 Member 5; Tetraethylammonium; Tritium; Valproic Acid; Xenopus laevis | 2000 |
Effect of short- and long-term treatment with valproate on carnitine homeostasis in humans.
Topics: Acetylcarnitine; Adult; Betaine; Biological Transport; Carnitine; Cell Line; Drug Administration Schedule; Female; HEK293 Cells; Homeostasis; Humans; Kidney Tubules, Proximal; Organic Cation Transport Proteins; Solute Carrier Family 22 Member 5; Valproic Acid | 2012 |
Betaine ameliorates prenatal valproic-acid-induced autism-like behavioral abnormalities in mice by promoting homocysteine metabolism.
Topics: Animals; Antimanic Agents; Autism Spectrum Disorder; Behavior, Animal; Betaine; Disease Models, Animal; Female; Homocysteine; Mice; Mice, Inbred ICR; Pregnancy; Prenatal Exposure Delayed Effects; Protective Agents; Social Behavior; Valproic Acid | 2019 |