Compounds > valproic acid

valproic acid and azathioprine

valproic acid has been researched along with azathioprine in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19902 (10.00)18.7374
1990's0 (0.00)18.2507
2000's7 (35.00)29.6817
2010's11 (55.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Chilovi, F; Dobrilla, G; Felder, M2
Bethke, F; Droste, DW; Flöel, A; Imai, T; Lohmann, H; Sunderkötter, C1
Bauret, P; Berthier, E; Blanc, F; Blayac, JP; Fabbro-Peray, P; Hanslik, B; Hillaire-Buys, D; Larrey, D; Melki, M; Pageaux, GP; Perney, P; Roques, V1
Kozu, T1
Annapandian, VM; Fleming, DH; John, GT; Mathew, BS1
Procházka, M; Procházka, V; Urbánek, K; Vinklerová, I1
Kiani, IG; Qureshi, SH; Shah, F1

Reviews

2 review(s) available for valproic acid and azathioprine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Drug-induced pancreatitis].
    Nihon rinsho. Japanese journal of clinical medicine, 2007, Oct-28, Volume: 65 Suppl 8

    Topics: Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Azathioprine; Cardiovascular Agents; Didanosine; Drug-Related Side Effects and Adverse Reactions; Humans; Pancreatitis; Psychotropic Drugs; Reference Standards; Time Factors; Valproic Acid

2007

Other Studies

18 other study(ies) available for valproic acid and azathioprine

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
[Proven relationship between drugs and pancreatitis].
    Deutsche medizinische Wochenschrift (1946), 1986, May-30, Volume: 111, Issue:22

    Topics: Asparaginase; Azathioprine; Diuretics; Drug-Related Side Effects and Adverse Reactions; Estrogens; Humans; Pancreatitis; Sulfonamides; Tetracycline; Valproic Acid

1986
[Acute drug-induced pancreatitis].
    Schweizerische medizinische Wochenschrift, 1985, Jun-22, Volume: 115, Issue:25

    Topics: Acute Disease; Asparaginase; Azathioprine; Chlorothiazide; Drug-Related Side Effects and Adverse Reactions; Estrogens; Furosemide; Humans; Pancreatitis; Sulfonamides; Tetracycline; Valproic Acid

1985
Therapy of Sneddon syndrome.
    European neurology, 2002, Volume: 48, Issue:3

    Topics: Adult; Antibodies, Antiphospholipid; Anticonvulsants; Aspirin; Azathioprine; Clopidogrel; Drug Therapy, Combination; Epilepsy; Female; Humans; Immunosuppressive Agents; Platelet Aggregation Inhibitors; Sneddon Syndrome; Ticlopidine; Valproic Acid

2002
Are drugs a risk factor of post-ERCP pancreatitis?
    Gastrointestinal endoscopy, 2003, Volume: 58, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Azathioprine; Cholangiopancreatography, Endoscopic Retrograde; Drug-Related Side Effects and Adverse Reactions; Estrogens; Female; Humans; Male; Mesalamine; Middle Aged; Morphine Derivatives; Multivariate Analysis; Pancreatitis; Prednisone; Retrospective Studies; Risk Factors; Valproic Acid

2003
Pharmacokinetic interaction between sodium valproate and mycophenolate in renal allograft recipients.
    Transplantation, 2009, Nov-15, Volume: 88, Issue:9

    Topics: Adolescent; Adult; Anticonvulsants; Area Under Curve; Azathioprine; Female; Glucocorticoids; Graft Rejection; Humans; Kidney Transplantation; Male; Methylprednisolone; Mycophenolic Acid; Seizures; Transplantation, Homologous; Valproic Acid

2009
Incidence, severity, and etiology of drug-induced acute pancreatitis.
    Digestive diseases and sciences, 2010, Volume: 55, Issue:10

    Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Azathioprine; Child; Child, Preschool; Crohn Disease; Cytarabine; Dexamethasone; Female; Humans; Immunosuppressive Agents; Incidence; Male; Mesalamine; Middle Aged; Mycophenolic Acid; Pancreatitis; Ramipril; Retrospective Studies; Risk Factors; Severity of Illness Index; Valproic Acid; Young Adult

2010
Depression and seizures as the main neuropsychiatric manifestation of mixed connective tissue disorder.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2014, Volume: 24 Suppl 2

    Topics: Adult; Antibodies, Antinuclear; Anticonvulsants; Antidepressive Agents, Second-Generation; Azathioprine; Citalopram; Depression; Electromyography; Female; Humans; Immunosuppressive Agents; Methylprednisolone; Mixed Connective Tissue Disease; Polymyositis; Seizures; Skin; Treatment Outcome; Valproic Acid

2014