Compounds > valproic acid

valproic acid and arsenic trioxide

valproic acid has been researched along with arsenic trioxide in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (10.00)29.6817
2010's8 (80.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Fan, LP; Lin, CM; Lin, FA; Shen, JZ; Ye, BG1
Jiang, J; Liu, XS; Peng, CY; Zheng, HT1
Liu, L; Qu, X; Wang, P; Wang, X; Zeng, H; Zhu, H; Zhu, X1
Wang, XN; Zhang, M1
Alvarez, EM; Blanco, GA; Cavaliere, V; Costantino, SN; Kornblihtt, L; Lombardo, T1
Wang, X; Zhang, M1
Han, BR; Park, HK; Park, WH1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1

Reviews

1 review(s) available for valproic acid and arsenic trioxide

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

9 other study(ies) available for valproic acid and arsenic trioxide

ArticleYear
[Synergistic effects of VPA and As2O3 on Molt-4 cells in vitro and its possible mechanisms].
    Zhongguo shi yan xue ye xue za zhi, 2008, Volume: 16, Issue:6

    Topics: Arsenic Trioxide; Arsenicals; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p15; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; Drug Synergism; Gene Expression Regulation, Neoplastic; Humans; Oxides; Up-Regulation; Valproic Acid

2008
Growth-inhibiting effects of arsenic trioxide plus epigenetic therapeutic agents on leukemia cell lines.
    Leukemia & lymphoma, 2010, Volume: 51, Issue:2

    Topics: Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Azacitidine; Cell Proliferation; Cell Survival; Decitabine; DNA Methylation; DNA Modification Methylases; DNA, Neoplasm; Drug Antagonism; Drug Synergism; Electrophoresis, Capillary; Growth Inhibitors; Histone Deacetylase Inhibitors; HL-60 Cells; Humans; Hydroxamic Acids; K562 Cells; Leukemia; Oxides; U937 Cells; Valproic Acid

2010
As2O3 synergistically reactivate latent HIV-1 by induction of NF-κB.
    Antiviral research, 2013, Volume: 100, Issue:3

    Topics: Arsenic Trioxide; Arsenicals; Aspirin; Cells, Cultured; Dose-Response Relationship, Drug; Genes, Reporter; HEK293 Cells; HIV Long Terminal Repeat; HIV-1; Humans; Jurkat Cells; Leukocytes, Mononuclear; Microscopy, Fluorescence; NF-kappa B; Oxides; Phorbol Esters; Signal Transduction; Transfection; Tumor Necrosis Factor-alpha; Valproic Acid; Virus Activation; Virus Latency

2013
[Apoptosis-inducing effect of valproic acid combined with arsenic trioxide on RPMI 8226 cells and its mechanism].
    Zhongguo shi yan xue ye xue za zhi, 2014, Volume: 22, Issue:4

    Topics: Apoptosis; Arsenic Trioxide; Arsenicals; bcl-2-Associated X Protein; Caspase 8; Caspase 9; Cell Line, Tumor; Cell Proliferation; Drug Synergism; Humans; Multiple Myeloma; Oxides; Proto-Oncogene Proteins c-bcl-2; Valproic Acid

2014
Synergism of arsenic trioxide and MG132 in Raji cells attained by targeting BNIP3, autophagy, and mitochondria with low doses of valproic acid and vincristine.
    European journal of cancer (Oxford, England : 1990), 2014, Volume: 50, Issue:18

    Topics: Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Autophagy; Cell Line, Tumor; Cell Survival; Drug Synergism; Enzyme Inhibitors; Humans; Leupeptins; Membrane Potential, Mitochondrial; Membrane Potentials; Membrane Proteins; Mitochondria; Oxides; Proto-Oncogene Proteins; U937 Cells; Up-Regulation; Valproic Acid; Vincristine

2014
Synergistic effects of valproic acid and arsenic trioxide on RPMI8226 cells in vitro and the possible underlying mechanisms.
    Molecular medicine reports, 2015, Volume: 12, Issue:1

    Topics: Acetylation; Apoptosis; Arsenic Trioxide; Arsenicals; bcl-2-Associated X Protein; Caspase 8; Caspase 9; Cell Line, Tumor; Cell Proliferation; Drug Synergism; Gene Expression Regulation, Neoplastic; Histone Deacetylase 1; Humans; Multiple Myeloma; Oxides; Proto-Oncogene Proteins c-bcl-2; Valproic Acid

2015
Combination of Arsenic Trioxide and Valproic Acid Efficiently Inhibits Growth of Lung Cancer Cells via G2/M-Phase Arrest and Apoptotic Cell Death.
    International journal of molecular sciences, 2020, Apr-10, Volume: 21, Issue:7

    Topics: Animals; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Biomarkers; Cell Line, Tumor; Disease Models, Animal; Drug Synergism; G2 Phase Cell Cycle Checkpoints; Humans; Lung Neoplasms; Membrane Potential, Mitochondrial; Mice; Valproic Acid; Xenograft Model Antitumor Assays

2020
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010