valproic acid and androstenedione

valproic acid has been researched along with androstenedione in 14 studies

Research

Studies (14)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (7.14)	18.7374
1990's	0 (0.00)	18.2507
2000's	9 (64.29)	29.6817
2010's	4 (28.57)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Houghton, J; Jarman, M; Parr, IB; Rowlands, MG	1
Isojärvi, JI; Knip, M; Kotila, MA; Lukkarinen, O; Myllylä, VV; Pakarinen, AJ; Rättyä, J; Turkka, J	1
Cockrell, JE; Legro, RS; McAllister, JM; Nelson-DeGrave, VL; Strauss, JF; Wickenheisser, JK; Wood, JR	1
Gates, JR	1
Isojärvi, JI; Juntunen, KS; Löfgren, E; Päivänsalo, M; Pakarinen, AJ; Rautakorpi, I; Tuomivaara, L	1
Isojärvi, JI; Mikkonen, K; Päivänsalo, M; Pakarinen, AJ; Tapanainen, P; Vainionpää, LK	1
Bjørnenak, T; Gjerstad, L; Mørkrid, L; Mørland, T; Røste, LS; Saetre, ER; Taubøll, E	1
Kantarci, M; Karaca, L; Koçak, N; Orbak, Z; Tan, H	1
Brodie, MJ; Butler, E; Hitiris, N; Leach, JP; Leach, VM; Parker, P; Sills, GJ; Stephen, LJ; Wilson, EA	1
Fisseha, S; Harada, M; Menon, KM; Peegel, H; Towns, R	1
Chihara, K; Fukuda, C; Funabashi, H; Inada, H; Kimura, J; Kunimatsu, T; Miyano, T; Miyawaki, I; Tateishi, Y; Yamashita, A	1
Bicknell, AB; Glister, C; Knight, PG; Michael, AE; Satchell, L	1
Minagawa, K; Oyanagi, R; Watanabe, T	1

Trials

1 trial(s) available for valproic acid and androstenedione

Article	Year
Sodium valproate versus lamotrigine: a randomised comparison of efficacy, tolerability and effects on circulating androgenic hormones in newly diagnosed epilepsy. Epilepsy research, 2007, Volume: 75, Issue:2-3 Topics: Adolescent; Adult; Aged; Androgens; Androstenedione; Anticonvulsants; Body Mass Index; Body Weight; Data Interpretation, Statistical; Epilepsy; Female; Humans; Lamotrigine; Male; Middle Aged; Sex Hormone-Binding Globulin; Testosterone; Triazines; Valproic Acid	2007

Article

Year

Sodium valproate versus lamotrigine: a randomised comparison of efficacy, tolerability and effects on circulating androgenic hormones in newly diagnosed epilepsy.

Epilepsy research, 2007, Volume: 75, Issue:2-3

Topics: Adolescent; Adult; Aged; Androgens; Androstenedione; Anticonvulsants; Body Mass Index; Body Weight; Data Interpretation, Statistical; Epilepsy; Female; Humans; Lamotrigine; Male; Middle Aged; Sex Hormone-Binding Globulin; Testosterone; Triazines; Valproic Acid

2007

Other Studies

13 other study(ies) available for valproic acid and androstenedione

Article	Year
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Inhibition of the formation of 4-hydroxyandrostenedione glucuronide by valproate. Biochemical pharmacology, 1988, Dec-01, Volume: 37, Issue:23 Topics: Androstenedione; Animals; Bile; Male; Microsomes, Liver; Rats; Rats, Inbred Strains; Valproic Acid	1988
Reproductive effects of valproate, carbamazepine, and oxcarbazepine in men with epilepsy. Neurology, 2001, Jan-09, Volume: 56, Issue:1 Topics: Adolescent; Adult; Androstenedione; Anticonvulsants; Carbamazepine; Dehydroepiandrosterone Sulfate; Epilepsies, Partial; Epilepsy, Generalized; Erectile Dysfunction; Humans; Hyperandrogenism; Male; Middle Aged; Oxcarbazepine; Retrospective Studies; Sex Hormone-Binding Globulin; Sexual Dysfunctions, Psychological; Testosterone; Valproic Acid	2001
Valproate potentiates androgen biosynthesis in human ovarian theca cells. Endocrinology, 2004, Volume: 145, Issue:2 Topics: 17-alpha-Hydroxyprogesterone; Acetylation; Adult; Androgens; Androstenedione; Cholesterol Side-Chain Cleavage Enzyme; Dehydroepiandrosterone; Female; Gene Expression; Histones; Humans; Phosphoproteins; Polycystic Ovary Syndrome; Progesterone; Steroid 17-alpha-Hydroxylase; Theca Cells; Valproic Acid	2004
Epilepsy versus antiepileptic drugs and gonadal function in men. Neurology, 2004, Jan-27, Volume: 62, Issue:2 Topics: Androstenedione; Anticonvulsants; Carbamazepine; Epilepsies, Partial; Epilepsy, Generalized; Humans; Hypogonadism; Luteinizing Hormone; Male; Oligospermia; Organ Size; Oxcarbazepine; Sperm Motility; Spermatozoa; Testis; Testosterone; Valproic Acid	2004
Effect of epilepsy and antiepileptic drugs on male reproductive health. Neurology, 2004, Jan-27, Volume: 62, Issue:2 Topics: Adult; Androstenedione; Anticonvulsants; Carbamazepine; Dehydroepiandrosterone Sulfate; Epilepsies, Partial; Epilepsy; Epilepsy, Generalized; Gonadotropins, Pituitary; Humans; Hypogonadism; Inhibins; Male; Organ Size; Oxcarbazepine; Prolactin; Sex Hormone-Binding Globulin; Sperm Motility; Spermatozoa; Testis; Testosterone; Valproic Acid	2004
Serum androgen levels and testicular structure during pubertal maturation in male subjects with epilepsy. Epilepsia, 2004, Volume: 45, Issue:7 Topics: Adolescent; Adult; Androgens; Androstenedione; Anticonvulsants; Carbamazepine; Child; Epilepsy; Humans; Lamotrigine; Male; Oxcarbazepine; Puberty; Regression Analysis; Sex Hormone-Binding Globulin; Testis; Testosterone; Triazines; Valproic Acid	2004
Antiepileptic drugs alter reproductive endocrine hormones in men with epilepsy. European journal of neurology, 2005, Volume: 12, Issue:2 Topics: Adult; Age Factors; Androstenedione; Anticonvulsants; C-Peptide; Carbamazepine; Carnitine; Dihydrotestosterone; Epilepsy; Follicle Stimulating Hormone; Gonadal Steroid Hormones; Humans; Insulin; Luteinizing Hormone; Male; Sex Hormone-Binding Globulin; Testosterone; Valproic Acid	2005
Valproate-induced insulin resistance in prepubertal girls with epilepsy. Journal of pediatric endocrinology & metabolism : JPEM, 2005, Volume: 18, Issue:10 Topics: Adolescent; Androstenedione; Anticonvulsants; Blood Glucose; Body Mass Index; Child; Cross-Sectional Studies; Epilepsy; Female; Humans; Insulin; Insulin Resistance; Lipids; Ovary; Prolactin; Puberty; Testosterone; Ultrasonography; Valproic Acid	2005
Inhibitory effect of valproic acid on ovarian androgen biosynthesis in rat theca-interstitial cells. Endocrine, 2010, Volume: 37, Issue:1 Topics: 17-Hydroxysteroid Dehydrogenases; 8-Bromo Cyclic Adenosine Monophosphate; Androgens; Androstenedione; Animals; Antimanic Agents; Cells, Cultured; Chorionic Gonadotropin; Cyclic AMP-Dependent Protein Kinases; Down-Regulation; Female; Gene Expression Regulation; Gonadal Steroid Hormones; Osmolar Concentration; Rats; Rats, Sprague-Dawley; RNA, Messenger; Steroid 17-alpha-Hydroxylase; Theca Cells; Valproic Acid	2010
Evaluation of ovarian toxicity of sodium valproate (VPA) using cultured rat ovarian follicles. The Journal of toxicological sciences, 2012, Volume: 37, Issue:3 Topics: Androstenedione; Animals; Anticonvulsants; Aromatase; Estradiol; Female; Granulosa Cells; Organ Culture Techniques; Ovarian Follicle; Progesterone; Rats; Rats, Sprague-Dawley; Steroids; Testosterone; Valproic Acid	2012
The anti-epileptic drug valproic acid (VPA) inhibits steroidogenesis in bovine theca and granulosa cells in vitro. PloS one, 2012, Volume: 7, Issue:11 Topics: Androstenedione; Animals; Anticonvulsants; Cattle; Cell Count; Cell Survival; Estradiol; Female; Follicle Stimulating Hormone; Gene Expression Regulation; Granulosa Cells; Histone Deacetylase Inhibitors; Insulin-Like Growth Factor I; Luteinizing Hormone; Progesterone; Real-Time Polymerase Chain Reaction; RNA, Messenger; Steroids; Theca Cells; Valproic Acid	2012
[Characteristics of women with epilepsy who developed polycystic ovary syndrome owing to the therapy with valproate sodium]. No to hattatsu = Brain and development, 2013, Volume: 45, Issue:4 Topics: Adolescent; Adult; Androstenedione; Epilepsy; Female; Humans; Polycystic Ovary Syndrome; Practice Guidelines as Topic; Risk Factors; Valproic Acid; Young Adult	2013