valproic acid and amitriptyline

valproic acid has been researched along with amitriptyline in 62 studies

Research

Studies (62)

Timeframe	Studies, this research(%)	All Research%
pre-1990	5 (8.06)	18.7374
1990's	9 (14.52)	18.2507
2000's	25 (40.32)	29.6817
2010's	21 (33.87)	24.3611
2020's	2 (3.23)	2.80

Authors

Authors	Studies
Andrews, PR; Craik, DJ; Martin, JL	1
Strassburg, CP; Tukey, RH	1
Topliss, JG; Yoshida, F	1
Chang, TK; Ensom, MH; Kiang, TK	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Lombardo, F; Obach, RS; Waters, NJ	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Glen, RC; Lowe, R; Mitchell, JB	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Raftery, H	1
Czuczwar, SJ; Gustaw, J; Kleinrok, Z	1
Bialer, M	1
Amendola D'Agostino, A; Fazio, A; Pisani, F; Primerano, G; Spina, E	1
Allers, G; Bertschy, G; Jounet, JM; Vandel, S	1
Dailey, JW; Jobe, PC	1
Awni, WM; Cavanaugh, J; Granneman, GR; Shi, H; Wong, SL	1
Dietrich, DE; Emrich, HM	1
Loewen, PS; Robinson, G; Zed, PJ	1
Goodwin, FK	1
Lubrich, B; van Calker, D	1
Rothrock, JF	1
Sinnott, C	1
Jain, V; Swartz, CM	1
Chmiel, JJ; Silberstein, SD; Winner, PK	1
Mayer, J; McDiarmid, T; Spry, H; Stanton, RN	1
Mannix, LK	1
Evans, RW; Láinez, MJ; Leira, R; Pascual, J	1
Canonico, PL; Colella, L; Dellarole, A; Ferri, S; Ghi, P; Orsetti, M	1
Dainese, F; Maggioni, F; Mainardi, F; Ruffatti, S; Zanchin, G	1
Canonico, PL; Colella, L; Dellarole, A; Ghi, P; Orsetti, M	1
Bertschy, G; Bondolfi, G; Golaz, J; Rachid, F	1
Bröcker, EB; Pfeuffer, P; Raith, P; Seitz, CS; Trautmann, A	1
Roberts-Thomson, KC; Teo, KS; Young, GD	1
Arnold, G; Schuh-Hofer, S	1
Davenport, R; Patel, HN; Patel, NC; Roberts, CK	1
Quimbo, RM; Rupnow, MF; Wertz, DA; Yaldo, AZ	1
Asmus, M; Holsboer, F; Kirmeier, T; Perisic, T; Rein, T; Tuorto, F; Uhr, M; Zimmermann, N; Zschocke, J	1
Fisar, Z; Hroudová, J; Raboch, J	1
Gaul, C; Straube, A	1
Ariyawardana, A; Pallegama, R; Ranasinghe, A; Sitheeque, M	1
Takekawa, K	1
Bhoi, SK; Kalita, J; Misra, UK	2
Burger, R; Deckert, J; Hohage, A; Pfuhlmann, B; Unterecker, S	1
Farrelly, LA; O'Callaghan, C; Savage, NT; Toulouse, A; Yilmazer-Hanke, DM	1
Owada, K	1
Ak, S; Atasayar, G; Can, FE; Cecener, G; Egeli, U; Eryilmaz, IE; Karli, N; Taskapilioglu, O; Tezcan, G; Tunca, B; Yildirim, O; Zarifoglu, M	1
He, A; Li, C; Song, D; Zhang, L	1
Adroja, B; Parekh, H; Prakash, S	1
Patterson-Gentile, C; Szperka, CL	1
Jena, M; Maiti, R; Mishra, A; Mishra, BR; Puliappadamb, HM	1
Deligianni, CI; Gil-Gouveia, R; Jassal, T; Lampl, C; MaassenVanDenBrink, A; Reuter, U; Sacco, S; Sanchez-Del-Rio, M; Uluduz, D; Versijpt, J; Zeraatkar, D	1

Reviews

15 review(s) available for valproic acid and amitriptyline

Article	Year
Human UDP-glucuronosyltransferases: metabolism, expression, and disease. Annual review of pharmacology and toxicology, 2000, Volume: 40 Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic	2000
UDP-glucuronosyltransferases and clinical drug-drug interactions. Pharmacology & therapeutics, 2005, Volume: 106, Issue:1 Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic	2005
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Clinical pharmacology of valpromide. Clinical pharmacokinetics, 1991, Volume: 20, Issue:2 Topics: Amitriptyline; Animals; Anticonvulsants; Biological Availability; Carbamazepine; Drug Interactions; Humans; Valproic Acid	1991
The use of anticonvulsants to augment antidepressant medication. The Journal of clinical psychiatry, 1998, Volume: 59 Suppl 5 Topics: Adult; Ambulatory Care; Amitriptyline; Anticonvulsants; Antidepressive Agents; Carbamazepine; Clinical Trials as Topic; Depressive Disorder; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Valproic Acid	1998
Medication-induced headache: overview and systematic review of therapeutic approaches. The Annals of pharmacotherapy, 1999, Volume: 33, Issue:1 Topics: Amitriptyline; Analgesics; Anti-Inflammatory Agents; Chronic Disease; Ergolines; Headache; Humans; MEDLINE; Piracetam; Randomized Controlled Trials as Topic; Substance Withdrawal Syndrome; Sumatriptan; Thiazines; Valproic Acid	1999
Anticonvulsant therapy and suicide risk in affective disorders. The Journal of clinical psychiatry, 1999, Volume: 60 Suppl 2 Topics: Amitriptyline; Anticonvulsants; Bipolar Disorder; Carbamazepine; Double-Blind Method; Female; Follow-Up Studies; Humans; Lamotrigine; Lithium; Male; Mood Disorders; Prospective Studies; Risk Factors; Suicide; Suicide Prevention; Triazines; Valproic Acid	1999
Clinical inquiries. What medication best prevents migraine in children? The Journal of family practice, 2003, Volume: 52, Issue:10 Topics: Amitriptyline; Child; Evidence-Based Medicine; Humans; Migraine Disorders; Propranolol; Valproic Acid	2003
Clinical advances in the preventive treatment of migraine. Acta neurologica Taiwanica, 2004, Volume: 13, Issue:4 Topics: Amitriptyline; Fructose; Humans; Migraine Disorders; Propranolol; Topiramate; Valproic Acid	2004
[Comorbidities in migraine patients]. MMW Fortschritte der Medizin, 2007, Apr-19, Volume: 149, Issue:16 Topics: Adult; Amitriptyline; Analgesics, Non-Narcotic; Anticonvulsants; Anxiety Disorders; Carotid Artery, Internal, Dissection; Comorbidity; Depression; Female; Foramen Ovale, Patent; Humans; Hypertension; Migraine Disorders; Prospective Studies; Risk Factors; Stroke; Valproic Acid	2007
Prevention of migraine attacks. First-choice treatments. Prescrire international, 2015, Volume: 24, Issue:157 Topics: Adrenergic beta-Antagonists; Amitriptyline; Analgesics; Anticonvulsants; Antidepressive Agents, Tricyclic; Female; Humans; Migraine Disorders; Pregnancy; Pregnancy Complications; Propranolol; Risk Factors; Risk Reduction Behavior; Treatment Outcome; Valproic Acid	2015
Unveiling the relative efficacy, safety and tolerability of prophylactic medications for migraine: pairwise and network-meta analysis. The journal of headache and pain, 2017, Volume: 18, Issue:1 Topics: Adult; Amines; Amitriptyline; Anticonvulsants; Cyclohexanecarboxylic Acids; Dizziness; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Migraine Disorders; Nausea; Pre-Exposure Prophylaxis; Propranolol; Randomized Controlled Trials as Topic; Topiramate; Treatment Outcome; Valproic Acid	2017
The Changing Landscape of Pediatric Migraine Therapy: A Review. JAMA neurology, 2018, 07-01, Volume: 75, Issue:7 Topics: Adolescent; Adrenergic beta-Antagonists; Amitriptyline; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Calcium Channel Blockers; Child; Cognitive Behavioral Therapy; Dihydroergotamine; Dopamine Antagonists; Fluid Therapy; Glucocorticoids; Headache Disorders, Secondary; Humans; Magnesium; Migraine Disorders; Nerve Block; Topiramate; Tryptamines; Valproic Acid	2018
Efficacy and Safety of Melatonin as Prophylaxis for Migraine in Adults: A Meta-analysis. Journal of oral & facial pain and headache, 2022,Summer, Volume: 36, Issue:3-4 Topics: Adult; Amitriptyline; Analgesics; Humans; Melatonin; Migraine Disorders; Valproic Acid	2022
The comparative effectiveness of migraine preventive drugs: a systematic review and network meta-analysis. The journal of headache and pain, 2023, May-19, Volume: 24, Issue:1 Topics: Adult; Amitriptyline; Antibodies, Monoclonal; Calcitonin Gene-Related Peptide; Gabapentin; Humans; Migraine Disorders; Network Meta-Analysis; Topiramate; Valproic Acid	2023

Trials

5 trial(s) available for valproic acid and amitriptyline

Article	Year
Anticonvulsant therapy and suicide risk in affective disorders. The Journal of clinical psychiatry, 1999, Volume: 60 Suppl 2 Topics: Amitriptyline; Anticonvulsants; Bipolar Disorder; Carbamazepine; Double-Blind Method; Female; Follow-Up Studies; Humans; Lamotrigine; Lithium; Male; Mood Disorders; Prospective Studies; Risk Factors; Suicide; Suicide Prevention; Triazines; Valproic Acid	1999
Management of chronic daily headache utilizing a uniform treatment pathway. Headache, 1999, Volume: 39, Issue:9 Topics: Adolescent; Adult; Amitriptyline; Analgesics, Non-Narcotic; Analgesics, Opioid; Chronic Disease; Drug Therapy, Combination; Female; GABA Agents; Headache; Humans; Male; Methadone; Middle Aged; Phenelzine; Valproic Acid	1999
Weight variations in the prophylactic therapy of primary headaches: 6-month follow-up. The journal of headache and pain, 2005, Volume: 6, Issue:4 Topics: Adrenergic beta-Antagonists; Adult; Amines; Amitriptyline; Analgesics, Non-Narcotic; Anticonvulsants; Atenolol; Cyclohexanecarboxylic Acids; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Migraine with Aura; Migraine without Aura; Pizotyline; Propranolol; Tension-Type Headache; Valproic Acid; Vasodilator Agents; Verapamil; Weight Gain	2005
Allodynia in migraine: clinical observation and role of prophylactic therapy. The Clinical journal of pain, 2013, Volume: 29, Issue:7 Topics: Adolescent; Adult; Amitriptyline; Analgesics, Non-Narcotic; Child; Comorbidity; Female; Humans; Hyperalgesia; India; Male; Middle Aged; Migraine Disorders; Pain Measurement; Prevalence; Risk Factors; Treatment Outcome; Valproic Acid; Young Adult	2013
Amitriptyline vs divalproate in migraine prophylaxis: a randomized controlled trial. Acta neurologica Scandinavica, 2013, Volume: 128, Issue:1 Topics: Adolescent; Adult; Amitriptyline; Analgesics, Non-Narcotic; Anticonvulsants; Cohort Studies; Delayed-Action Preparations; Female; Humans; Male; Middle Aged; Migraine Disorders; Pain Measurement; Treatment Outcome; Valproic Acid; Young Adult	2013

Other Studies

43 other study(ies) available for valproic acid and amitriptyline

Article	Year
Functional group contributions to drug-receptor interactions. Journal of medicinal chemistry, 1984, Volume: 27, Issue:12 Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship	1984
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Predicting phospholipidosis using machine learning. Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5 Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine	2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
The management of post herpetic pain using sodium valproate and amitriptyline. Irish medical journal, 1979, Sep-28, Volume: 72, Issue:9 Topics: Amitriptyline; Herpes Zoster; Humans; Pain; Valproic Acid	1979
Influence of antidepressant drugs on seizure susceptibility and the anticonvulsant activity of valproate in mice. Journal of neural transmission. Supplementum, 1991, Volume: 34 Topics: Amitriptyline; Animals; Desipramine; Dose-Response Relationship, Drug; Electroshock; Imipramine; Male; Mice; Seizures; Valproic Acid	1991
Valproic acid-amitriptyline interaction in man. Therapeutic drug monitoring, 1986, Volume: 8, Issue:3 Topics: Adult; Amitriptyline; Drug Interactions; Drug Therapy, Combination; Female; Half-Life; Humans; Male; Valproic Acid	1986
Valpromide increases the plasma concentrations of amitriptyline and its metabolite nortriptyline in depressive patients. Therapeutic drug monitoring, 1988, Volume: 10, Issue:4 Topics: Adult; Amitriptyline; Anticonvulsants; Depressive Disorder; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Nortriptyline; Valproic Acid	1988
Anticonvulsant drugs and the genetically epilepsy-prone rat. Federation proceedings, 1985, Volume: 44, Issue:10 Topics: Acoustic Stimulation; Amitriptyline; Animals; Anticonvulsants; Carbamazepine; Desipramine; Disease Models, Animal; Epilepsy; Ethosuximide; Imipramine; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Seizures; Valproic Acid	1985
Effects of divalproex sodium on amitriptyline and nortriptyline pharmacokinetics. Clinical pharmacology and therapeutics, 1996, Volume: 60, Issue:1 Topics: Adult; Amitriptyline; Anticonvulsants; Antidepressive Agents, Tricyclic; Cytochrome P-450 Enzyme System; Drug Interactions; Female; Humans; Male; Middle Aged; Nortriptyline; Valproic Acid	1996
New "triptans" and other drugs for migraine. The Medical letter on drugs and therapeutics, 1998, Oct-09, Volume: 40, Issue:1037 Topics: Adrenergic beta-Antagonists; Amitriptyline; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents, Tricyclic; Calcium Channel Blockers; Dihydroergotamine; Drug Interactions; Ergotamine; Humans; Indoles; Methysergide; Migraine Disorders; Naproxen; Oxazoles; Oxazolidinones; Piperidines; Propranolol; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists; Sumatriptan; Time Factors; Timolol; Triazoles; Tryptamines; Valproic Acid; Vasoconstrictor Agents	1998
Inhibition of the high affinity myo-inositol transport system: a common mechanism of action of antibipolar drugs? Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1999, Volume: 21, Issue:4 Topics: Adrenergic Uptake Inhibitors; Amitriptyline; Animals; Antimanic Agents; Astrocytes; Biological Transport; Brain; Carbamazepine; Carrier Proteins; Heat-Shock Proteins; Humans; Inositol; Lithium; Membrane Proteins; Rats; Rats, Wistar; RNA, Messenger; Symporters; Time Factors; Tumor Cells, Cultured; Valproic Acid	1999
Problems recruiting cancer patients to a comparative clinical trial of drug treatments for neuropathic pain in palliative care. Journal of pain and symptom management, 2002, Volume: 23, Issue:4 Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Humans; Multicenter Studies as Topic; Neoplasms; Neuroprotective Agents; Pain; Palliative Care; Patients; Randomized Controlled Trials as Topic; Valproic Acid	2002
Charcoal enhancement of treatment for tricyclic-induced mania. Pharmacopsychiatry, 2002, Volume: 35, Issue:5 Topics: Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Antidotes; Bipolar Disorder; Charcoal; Depressive Disorder; Drug Overdose; Female; Humans; Nortriptyline; Treatment Outcome; Valproic Acid	2002
Migraine preventive medication reduces resource utilization. Headache, 2003, Volume: 43, Issue:3 Topics: Amitriptyline; Cohort Studies; Health Resources; Humans; Migraine Disorders; Practice Guidelines as Topic; Retrospective Studies; Serotonin Receptor Agonists; Sumatriptan; United States; Valproic Acid	2003
Bending the rule of monotherapy for migraine prevention? Headache, 2005, Volume: 45, Issue:6 Topics: Adrenergic beta-Antagonists; Adult; Amitriptyline; Drug Therapy, Combination; Female; Humans; Migraine Disorders; Propranolol; Valproic Acid	2005
Effects of chronic administration of olanzapine, amitriptyline, haloperidol or sodium valproate in naive and anhedonic rats. The international journal of neuropsychopharmacology, 2006, Volume: 9, Issue:4 Topics: Amitriptyline; Animals; Antidepressive Agents; Benzodiazepines; Eating; Haloperidol; Male; Olanzapine; Rats; Rats, Wistar; Self Administration; Sucrose; Valproic Acid	2006
Modification of spatial recognition memory and object discrimination after chronic administration of haloperidol, amitriptyline, sodium valproate or olanzapine in normal and anhedonic rats. The international journal of neuropsychopharmacology, 2007, Volume: 10, Issue:3 Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Chronic Disease; Conditioning, Operant; Discrimination, Psychological; Dose-Response Relationship, Drug; Food Preferences; Haloperidol; Male; Maze Learning; Memory; Olanzapine; Rats; Rats, Wistar; Recognition, Psychology; Space Perception; Stress, Psychological; Taste; Valproic Acid	2007
Induction of a mixed depressive episode during rTMS treatment in a patient with refractory major depression. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2006, Volume: 7, Issue:4 Topics: Adult; Amitriptyline; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Antimanic Agents; Depressive Disorder, Major; Female; Humans; Methadone; Mood Disorders; Narcotics; Opipramol; Paroxetine; Prazepam; Psychiatric Status Rating Scales; Serotonin Syndrome; Severity of Illness Index; Substance-Related Disorders; Transcranial Magnetic Stimulation; Trazodone; Valproic Acid	2006
Pharmacological prevention of migraine: to be considered case by case. Prescrire international, 2006, Volume: 15, Issue:85 Topics: Adrenergic beta-Antagonists; Amitriptyline; Anticonvulsants; Antidepressive Agents; Cost-Benefit Analysis; Flunarizine; France; Humans; Methysergide; Migraine Disorders; Pizotyline; Propranolol; Serotonin Antagonists; United Kingdom; Valproic Acid	2006
Anticonvulsant hypersensitivity syndrome: cross-reactivity with tricyclic antidepressant agents. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2006, Volume: 97, Issue:5 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amines; Amitriptyline; Anticonvulsants; Antidepressive Agents, Tricyclic; Benzodiazepines; Carbamazepine; Cross Reactions; Cyclohexanecarboxylic Acids; Doxepin; Drug Hypersensitivity; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Molecular Structure; Phenytoin; Skin Tests; Syndrome; Valproic Acid	2006
Drug-induced Brugada syndrome with ST-T wave alternans and long QT. Internal medicine journal, 2007, Volume: 37, Issue:3 Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Arrhythmias, Cardiac; Bipolar Disorder; Brugada Syndrome; Electrocardiography; Fatal Outcome; Haloperidol; Humans; Lithium Compounds; Long QT Syndrome; Male; Valproic Acid	2007
Hallucinations during lamotrigine treatment. The Nurse practitioner, 2008, Volume: 33, Issue:3 Topics: Adolescent; Amitriptyline; Anticonvulsants; Antidepressive Agents, Tricyclic; Erythema Infectiosum; Female; Hallucinations; Humans; Lamotrigine; Triazines; Valproic Acid	2008
Persistence with migraine prophylactic treatment and acute migraine medication utilization in the managed care setting. Clinical therapeutics, 2008, Volume: 30, Issue:12 Topics: Adult; Age Factors; Amitriptyline; Cohort Studies; Databases, Factual; Dose-Response Relationship, Drug; Drug Prescriptions; Drug Therapy, Combination; Drug Utilization Review; Female; Fructose; Humans; Kaplan-Meier Estimate; Male; Managed Care Programs; Medication Adherence; Middle Aged; Migraine Disorders; Proportional Hazards Models; Propranolol; Retrospective Studies; Sex Factors; Time Factors; Timolol; Topiramate; Valproic Acid	2008
Valproate and amitriptyline exert common and divergent influences on global and gene promoter-specific chromatin modifications in rat primary astrocytes. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2010, Volume: 35, Issue:3 Topics: Amitriptyline; Animals; Animals, Newborn; Astrocytes; Cells, Cultured; Chromatin; DNA Methylation; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; Valproic Acid	2010
Inhibition of monoamine oxidase activity by antidepressants and mood stabilizers. Neuro endocrinology letters, 2010, Volume: 31, Issue:5 Topics: Affect; Amitriptyline; Animals; Antidepressive Agents; Antimanic Agents; Benzodiazepines; Cerebral Cortex; Citalopram; Clorgyline; Cocaine; Cyclohexanols; Desipramine; Fluoxetine; Imipramine; In Vitro Techniques; Iproniazid; Lithium; Mianserin; Mirtazapine; Mitochondria; Moclobemide; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Morpholines; Olanzapine; Pargyline; Reboxetine; Swine; Thiazepines; Valproic Acid; Venlafaxine Hydrochloride	2010
[Chronic migraine: not well known but not rare!]. MMW Fortschritte der Medizin, 2011, Mar-24, Volume: 153, Issue:12 Topics: Amitriptyline; Analgesics; Anticonvulsants; Antidepressive Agents, Tricyclic; Chronic Disease; Female; Fructose; Humans; Male; Migraine Disorders; Risk Factors; Topiramate; Tryptamines; Valproic Acid	2011
Use of single- and multi-drug regimens in the management of classic (idiopathic) trigeminal neuralgia: an 11-year experience at a single Sri Lankan institution. Journal of investigative and clinical dentistry, 2012, Volume: 3, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Amines; Amitriptyline; Analgesics; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Pain Measurement; Phenytoin; Retrospective Studies; Sri Lanka; Treatment Outcome; Trigeminal Neuralgia; Valproic Acid	2012
[Case of acute pain of herpes zoster with preceding immobility of the shoulder]. Masui. The Japanese journal of anesthesiology, 2012, Volume: 61, Issue:7 Topics: Acute Pain; Amitriptyline; Anticonvulsants; Antidepressive Agents; Autonomic Nerve Block; Herpes Zoster; Humans; Hypokinesia; Male; Middle Aged; Nephrotic Syndrome; Shoulder; Treatment Outcome; Valproic Acid	2012
Interaction of valproic acid and amitriptyline: analysis of therapeutic drug monitoring data under naturalistic conditions. Journal of clinical psychopharmacology, 2013, Volume: 33, Issue:4 Topics: Adult; Aged; Amitriptyline; Antidepressive Agents; Chi-Square Distribution; Delirium; Depressive Disorder, Treatment-Resistant; Drug Dosage Calculations; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Retrospective Studies; Valproic Acid; Young Adult	2013
Therapeutic concentrations of valproate but not amitriptyline increase neuropeptide Y (NPY) expression in the human SH-SY5Y neuroblastoma cell line. Regulatory peptides, 2013, Sep-10, Volume: 186 Topics: Amitriptyline; Anticonvulsants; Cell Line, Tumor; Cell Survival; Gene Expression; Humans; Neuroblastoma; Neuropeptide Y; Tetradecanoylphorbol Acetate; Valproic Acid	2013
[Therapeuetic aspects of cluster headache in the practical clinical site]. Rinsho shinkeigaku = Clinical neurology, 2013, Volume: 53, Issue:11 Topics: Adult; Amines; Amitriptyline; Cluster Headache; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Injections, Subcutaneous; Male; Middle Aged; Self Care; Sumatriptan; Valproic Acid; Young Adult	2013
Association of MDR1, CYP2D6, and CYP2C19 gene polymorphisms with prophylactic migraine treatment response. Journal of the neurological sciences, 2016, Jul-15, Volume: 366 Topics: Adult; Amitriptyline; ATP Binding Cassette Transporter, Subfamily B; Central Nervous System Agents; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2D6; Drug Resistance; Female; Fructose; Gene Frequency; Genetic Association Studies; Humans; Male; Migraine Disorders; Polymorphism, Genetic; Propranolol; Risk Factors; Topiramate; Treatment Outcome; Valproic Acid	2016
Serotonin syndrome in patients with headache disorders. BMJ case reports, 2017, Aug-07, Volume: 2017 Topics: Acetaminophen; Adult; Amitriptyline; Analgesics; Cluster Headache; Drug Therapy, Combination; Flunarizine; Humans; Lithium; Male; Middle Aged; Migraine Disorders; Serotonin Agents; Serotonin Syndrome; Tramadol; Valproic Acid	2017