Compounds > valproic acid

valproic acid and aminopyrine

valproic acid has been researched along with aminopyrine in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19903 (50.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Honda, K; Izumi, T; Miyaji, Y; Nakayama, S; Okazaki, O; Okudaira, N; Shiosakai, K; Sugiyama, D; Suzuki, W; Takakusa, H; Watanabe, A1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Helge, H; Jäger-Roman, E; Kuhnz, W; Nau, H; Rating, D1
Borchert, HH; Pfeifer, S; Schuster, S1
Häuser, I; Helge, H; Koch, S; Nau, H; Rating, D1

Other Studies

6 other study(ies) available for valproic acid and aminopyrine

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Combination of GSH trapping and time-dependent inhibition assays as a predictive method of drugs generating highly reactive metabolites.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:7

    Topics: Glutathione; Pharmacology; Sulfur Radioisotopes

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Enzyme induction in neonates after fetal exposure to antiepileptic drugs.
    Pediatric pharmacology (New York, N.Y.), 1983, Volume: 3, Issue:3-4

    Topics: Aminopyrine; Aminopyrine N-Demethylase; Anticonvulsants; Breath Tests; Carbamazepine; Carbon Radioisotopes; Enzyme Induction; Female; Humans; Infant, Newborn; Liver; Male; Maternal-Fetal Exchange; Phenobarbital; Phenytoin; Pregnancy; Primidone; Valproic Acid

1983
[Metabolic interaction of valproic acid (author's transl)].
    Die Pharmazie, 1980, Volume: 34, Issue:5-6

    Topics: Aminopyrine; Aniline Compounds; Animals; Binding, Competitive; Codeine; Dealkylation; Glucuronosyltransferase; Hydroxylation; In Vitro Techniques; Liver; Rats; Valproic Acid

1980
Valproic acid and its metabolites: placental transfer, neonatal pharmacokinetics, transfer via mother's milk and clinical status in neonates of epileptic mothers.
    The Journal of pharmacology and experimental therapeutics, 1981, Volume: 219, Issue:3

    Topics: Abnormalities, Drug-Induced; Aminopyrine; Breath Tests; Epilepsy; Female; Fetal Blood; Half-Life; Humans; Infant, Newborn; Kinetics; Male; Maternal-Fetal Exchange; Milk, Human; Pregnancy; Pregnancy Complications; Valproic Acid

1981