valproic acid has been researched along with alpha-synuclein in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chuang, DM; Leng, Y | 1 |
| Batti, L; Contestabile, A; Crochemore, C; Monti, B; Polazzi, E; Virgili, M | 1 |
| Contestabile, A; Gatta, V; Monti, B; Piretti, F; Raffaelli, SS; Virgili, M | 1 |
| Ferreiro, E; Marques, SC; Oliveira, CR; Pereira, CM; Resende, R; Simões, I | 1 |
| Caldwell, GA; Caldwell, KA; Carrasquilla, A; Hicks, ML; Kautu, BB | 1 |
| Perez, RG; Segura-Ulate, I; Vargas-Medrano, J; Yang, B | 1 |
6 other study(ies) available for valproic acid and alpha-synuclein
| Article | Year |
|---|---|
Endogenous alpha-synuclein is induced by valproic acid through histone deacetylase inhibition and participates in neuroprotection against glutamate-induced excitotoxicity.
Topics: Acetylation; alpha-Synuclein; Animals; Anticonvulsants; Antimanic Agents; Cells, Cultured; Cerebellum; Cerebral Cortex; Glutamic Acid; Histone Deacetylase Inhibitors; Histones; Hydroxamic Acids; Neuroprotective Agents; Oligonucleotides, Antisense; Phenylbutyrates; Promoter Regions, Genetic; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; RNA, Small Interfering; Ubiquitin-Conjugating Enzymes; Valproic Acid | 2006 |
Alpha-synuclein protects cerebellar granule neurons against 6-hydroxydopamine-induced death.
Topics: alpha-Synuclein; Animals; Apoptosis; Blotting, Western; Cell Death; Cell Nucleus; Cell Survival; Cerebellum; Cytoplasmic Granules; Cytosol; Gene Silencing; Immunoprecipitation; Male; Neurons; Neuroprotective Agents; Oligonucleotides, Antisense; Oxidopamine; Proteasome Endopeptidase Complex; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Sympatholytics; Translocation, Genetic; Valproic Acid | 2007 |
Valproic acid is neuroprotective in the rotenone rat model of Parkinson's disease: involvement of alpha-synuclein.
Topics: alpha-Synuclein; Analysis of Variance; Animals; Brain; Cell Death; Chromatography, High Pressure Liquid; Disease Models, Animal; DNA Fragmentation; Dopamine; Drug Administration Schedule; Gene Expression Regulation; Histone Deacetylases; Immunoprecipitation; Insecticides; Male; Molecular Weight; Neuroprotective Agents; Parkinson Disease, Secondary; Rats; Rats, Wistar; Rotenone; Valproic Acid | 2010 |
Effect of α-synuclein on amyloid β-induced toxicity: relevance to Lewy body variant of Alzheimer disease.
Topics: alpha-Synuclein; Alzheimer Disease; Amyloid beta-Peptides; Animals; Caspase 3; Cerebral Cortex; Neurons; Peptide Fragments; Rats; Valproic Acid | 2013 |
Valproic acid ameliorates C. elegans dopaminergic neurodegeneration with implications for ERK-MAPK signaling.
Topics: alpha-Synuclein; Animals; Anticonvulsants; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Dopaminergic Neurons; Humans; MAP Kinase Kinase 2; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Nerve Degeneration; Neuroprotective Agents; Parkinson Disease; RNA Interference; Valproic Acid | 2013 |
FTY720 (Fingolimod) reverses α-synuclein-induced downregulation of brain-derived neurotrophic factor mRNA in OLN-93 oligodendroglial cells.
Topics: Acetylation; alpha-Synuclein; Animals; beta-Synuclein; Brain-Derived Neurotrophic Factor; Cells, Cultured; Down-Regulation; Fingolimod Hydrochloride; Histones; Humans; Mutation; Neuroglia; Neurons; Oligodendroglia; Rats; Valproic Acid | 2017 |