valproic acid and adenosine

valproic acid has been researched along with adenosine in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.56)18.7374
1990's3 (16.67)18.2507
2000's4 (22.22)29.6817
2010's8 (44.44)24.3611
2020's2 (11.11)2.80

Authors

AuthorsStudies
Bruno-Blanch, L; Gálvez, J; García-Domenech, R1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Czuczwar, SJ; Janusz, W; Kleinrok, Z; Szczepanik, B; Wamil, A1
Fredholm, BB; Hare, TA; Murros, K; Ohisalo, JJ1
David, J; Joseph, T; Kulkarni, C1
Borowicz, KK; Czuczwar, SJ; Kleinrok, Z2
Bogo, MR; Bonan, CD; Nery, LR; Piato, AL; Schaefer, IC; Siebel, AM1
Kaminska, B; Maleszewska, M; Steranka, A1
Cappellacci, L; D'Alessandro, N; Del Bello, F; Ferro, A; Franchetti, P; Grifantini, M; Hofer, A; Jayaram, HN; Kusumanchi, P; Meli, M; Petrelli, R; Tolomeo, M; Torquati, I; Vita, P; Vodnala, M1
Akula, KK; Boison, D; Coffman, SQ; Lusardi, TA; Masino, SA; Ruskin, DN1
Bertoncello, KT; Bonan, CD1
Boison, D; Daniels, SD1

Reviews

2 review(s) available for valproic acid and adenosine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Bipolar mania and epilepsy pathophysiology and treatment may converge in purine metabolism: A new perspective on available evidence.
    Neuropharmacology, 2023, Dec-15, Volume: 241

    Topics: Adenosine; Adenosine Triphosphate; Antimanic Agents; Bipolar Disorder; Epilepsy; Humans; Hydrocortisone; Mania; Purines; Uric Acid; Valproic Acid

2023

Other Studies

16 other study(ies) available for valproic acid and adenosine

ArticleYear
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity.
    Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16

    Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship

2003
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Differential effects of agents enhancing purinergic transmission upon the antielectroshock efficacy of carbamazepine, diphenylhydantoin, diazepam, phenobarbital, and valproate in mice.
    Journal of neural transmission. General section, 1990, Volume: 81, Issue:2

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Anticonvulsants; Body Temperature Regulation; Diazepam; Electroshock; Female; Mice; Phenylisopropyladenosine; Receptors, Purinergic; Seizures; Valproic Acid

1990
Concentrations of gamma-aminobutyric acid and adenosine in the CSF in progressive myoclonus epilepsy without Lafora's bodies.
    Archives of neurology, 1983, Volume: 40, Issue:10

    Topics: Adenosine; Adolescent; Adult; Clonazepam; Epilepsies, Myoclonic; Female; gamma-Aminobutyric Acid; Humans; Male; Valproic Acid

1983
Involvement of adenosine in postictal events in rats given electroshock.
    Indian journal of physiology and pharmacology, 1994, Volume: 38, Issue:1

    Topics: Adenosine; Animals; Anticonvulsants; Behavior, Animal; Carbamazepine; Electroshock; Female; Hindlimb; Male; Rats; Rats, Wistar; Seizures; Theophylline; Valproic Acid

1994
N6-2-(4-aminophenyl)ethyl-adenosine enhances the anticonvulsive activity of antiepileptic drugs.
    European journal of pharmacology, 1997, May-30, Volume: 327, Issue:2-3

    Topics: Adenosine; Animals; Anticonvulsants; Body Temperature; Carbamazepine; Darkness; Drug Synergism; Electroshock; Female; Memory; Mice; Motor Activity; Phenobarbital; Phenytoin; Purinergic P1 Receptor Agonists; Valproic Acid

1997
N(6)-2-(4-aminophenyl)ethyl-adenosine enhances the anticonvulsive action of conventional antiepileptic drugs in the kindling model of epilepsy in rats.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2000, Volume: 10, Issue:4

    Topics: Adenosine; Amygdala; Animals; Anticonvulsants; Avoidance Learning; Carbamazepine; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Epilepsy; Kindling, Neurologic; Male; Rats; Rats, Wistar; Theophylline; Valproic Acid

2000
Antiepileptic drugs prevent changes in adenosine deamination during acute seizure episodes in adult zebrafish.
    Pharmacology, biochemistry, and behavior, 2013, Volume: 104

    Topics: Adenine Nucleotides; Adenosine; Adenosine Deaminase; Amines; Animals; Anticonvulsants; Brain; Cyclohexanecarboxylic Acids; Disease Models, Animal; Female; Gabapentin; gamma-Aminobutyric Acid; Gene Expression; Male; Pentylenetetrazole; Phenytoin; Seizures; Valproic Acid; Zebrafish

2013
The effects of selected inhibitors of histone modifying enzyme on C6 glioma cells.
    Pharmacological reports : PR, 2014, Volume: 66, Issue:1

    Topics: Acetylation; Adenosine; Animals; Azepines; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Enzyme Inhibitors; Epigenesis, Genetic; Glioma; Histones; Hydroxamic Acids; Piperazines; Quinazolines; Rats; Valproic Acid

2014
From the covalent linkage of drugs to novel inhibitors of ribonucleotide reductase: synthesis and biological evaluation of valproic esters of 3'-C-methyladenosine.
    Bioorganic & medicinal chemistry letters, 2014, Nov-15, Volume: 24, Issue:22

    Topics: Adenosine; Adenosine Triphosphate; Allosteric Regulation; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Enzyme Inhibitors; Esters; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Kinetics; Ribonucleotide Reductases; Valproic Acid

2014
Ketogenic diet prevents epileptogenesis and disease progression in adult mice and rats.
    Neuropharmacology, 2015, Volume: 99

    Topics: Adenosine; Animals; Anticonvulsants; Diet, Ketogenic; Disease Models, Animal; Disease Progression; DNA Methylation; Hippocampus; Kindling, Neurologic; Male; Mice; Pentylenetetrazole; Pilocarpine; Random Allocation; Rats, Wistar; Seizures; Status Epilepticus; Valproic Acid

2015
The Effect of Adenosine Signaling on Memory Impairment Induced by Pentylenetetrazole in Zebrafish.
    Neurochemical research, 2023, Volume: 48, Issue:6

    Topics: Adenosine; Animals; Dipyridamole; Epilepsy; Pentylenetetrazole; Quality of Life; Seizures; Valproic Acid; Zebrafish

2023