valproic acid has been researched along with 4-aminopyridine in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (28.57) | 18.2507 |
| 2000's | 6 (42.86) | 29.6817 |
| 2010's | 3 (21.43) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Avoli, M; Fueta, Y | 1 |
| Avoli, M; Fueta, Y; Siniscalchi, A; Tancredi, V | 1 |
| Duburs, G; Germane, SK; Karpova, MN; Klusha, VE; Pankov, OIu | 1 |
| Andersen, PH; Burns, CM; Chang, H; Crider, AM; el-Assadi, AA; Hinko, CN; Ho, B; Kliem, MA; Klitgaard, H; Seo, TH; Steinmiller, CL; Tietz, EI; Venkatarangan, P | 1 |
| Brückner, C; Heinemann, U | 1 |
| Bingmann, D; Bonnet, U; Hufnagel, A; Leniger, T; Wiemann, M | 1 |
| Baraban, SC; Barbaro, NM; Smyth, MD | 1 |
| Amat, G; Armijo, JA; Cuadrado, A | 1 |
| Martín, ED; Pozo, MA | 2 |
| Avoli, M; Biagini, G; D'Antuono, M; Gotman, J; Köhling, R; Ricalzone, S | 1 |
| Buijs, RM; Gómez, CD; Sitges, M | 1 |
| Franke, H; Illes, P; Khan, MT; Liu, J; Nerlich, J; Tang, Y | 1 |
| Golizadeh, M; Jourahmad, Z; Maghbooli, M | 1 |
1 review(s) available for valproic acid and 4-aminopyridine
| Article | Year |
|---|---|
Refractory Convulsive Status Epilepticus Provoked by Intoxication with Dalfampridine in a Patient with Multiple Sclerosis and Depression Disorder: A Case Report and Literature Review.
Topics: 4-Aminopyridine; Adult; Epilepsy; Humans; Multiple Sclerosis; Sodium; Status Epilepticus; Valproic Acid; Young Adult | 2023 |
13 other study(ies) available for valproic acid and 4-aminopyridine
| Article | Year |
|---|---|
Pattern- and age-dependency of the antiepileptic effects induced by valproic acid in the rat hippocampus.
Topics: 4-Aminopyridine; Age Factors; Animals; Epilepsy; Hippocampus; Rats; Rats, Inbred Strains; Valproic Acid | 1991 |
Extracellular magnesium and anticonvulsant effects of valproate in young rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Animals; Epilepsy; gamma-Aminobutyric Acid; Hippocampus; Ionophores; Magnesium; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Valproic Acid | 1995 |
[The antiepileptic effects of the combined action of the new 1,4-dihydropyridine derivative glutapyrone with sodium valproate and phenobarbital].
Topics: 4-Aminopyridine; Animals; Anticonvulsants; Dihydropyridines; Drug Evaluation, Preclinical; Drug Therapy, Combination; Electroshock; Epilepsies, Partial; Epilepsy, Generalized; Glutamates; Male; Mice; Mice, Inbred ICR; Pentylenetetrazole; Phenobarbital; Rats; Rats, Wistar; Valproic Acid | 1993 |
Anticonvulsant activity of novel derivatives of 2- and 3-piperidinecarboxylic acid in mice and rats.
Topics: 4-Aminopyridine; Amygdala; Animals; Anticonvulsants; Brain; Convulsants; Kindling, Neurologic; Male; Mice; Mice, Inbred Strains; Molecular Structure; N-Methylaspartate; Neurotoxins; Nipecotic Acids; Pentylenetetrazole; Pipecolic Acids; Proline; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Phencyclidine; Seizures; Structure-Activity Relationship; Valproic Acid | 1996 |
Effects of standard anticonvulsant drugs on different patterns of epileptiform discharges induced by 4-aminopyridine in combined entorhinal cortex-hippocampal slices.
Topics: 4-Aminopyridine; Animals; Anticonvulsants; Carbamazepine; Entorhinal Cortex; Epilepsies, Partial; Female; gamma-Aminobutyric Acid; Hippocampus; Hypnotics and Sedatives; Male; Pentobarbital; Phenobarbital; Phenytoin; Prohibitins; Rats; Rats, Wistar; Valproic Acid | 2000 |
Different effects of GABAergic anticonvulsants on 4-aminopyridine-induced spontaneous GABAergic hyperpolarizations of hippocampal pyramidal cells--implication for their potency in migraine therapy.
Topics: 4-Aminopyridine; Acetates; Amines; Analgesics; Animals; Anticonvulsants; Convulsants; Cyclohexanecarboxylic Acids; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; Humans; Membrane Potentials; Migraine Disorders; Nipecotic Acids; Pyramidal Cells; Tiagabine; Time Factors; Valproic Acid; Vigabatrin | 2000 |
Effects of antiepileptic drugs on induced epileptiform activity in a rat model of dysplasia.
Topics: 4-Aminopyridine; Action Potentials; Animals; Animals, Newborn; Anticonvulsants; Carbamazepine; Disease Models, Animal; Electroencephalography; Epilepsy; Ethosuximide; Female; Hippocampus; In Vitro Techniques; Lamotrigine; Methylazoxymethanol Acetate; Phenobarbital; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Triazines; Valproic Acid | 2002 |
Is the interaction between felbamate and valproate against seizures induced by 4-aminopyridine and pentylenetetrazole in mice beneficial?
Topics: 4-Aminopyridine; Analysis of Variance; Animals; Brain; Chromatography, Liquid; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Felbamate; gamma-Aminobutyric Acid; Glutamic Acid; Male; Mice; Mice, Inbred Strains; Neurotoxicity Syndromes; Pentylenetetrazole; Phenylcarbamates; Propylene Glycols; Reaction Time; Seizures; Toxicity Tests; Valproic Acid | 2003 |
Valproate suppresses status epilepticus induced by 4-aminopyridine in CA1 hippocampus region.
Topics: 4-Aminopyridine; Animals; Carbamazepine; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Hippocampus; Injections; Male; Phenytoin; Rats; Rats, Wistar; Status Epilepticus; Valproic Acid | 2003 |
Valproate reduced synaptic activity increase induced by 4-aminopyridine at the hippocampal CA3-CA1 synapse.
Topics: 4-Aminopyridine; Animals; Anticonvulsants; Drug Antagonism; Hippocampus; In Vitro Techniques; Potassium Channel Blockers; Pyramidal Cells; Rats; Rats, Wistar; Synapses; Synaptic Transmission; Valproic Acid | 2004 |
Antiepileptic drugs abolish ictal but not interictal epileptiform discharges in vitro.
Topics: 4-Aminopyridine; Action Potentials; Animals; Anticonvulsants; Brain; Carbamazepine; Convulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Entorhinal Cortex; Fructose; In Vitro Techniques; Male; Neurons; Patch-Clamp Techniques; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Seizures; Topiramate; Valproic Acid | 2010 |
The anti-seizure drugs vinpocetine and carbamazepine, but not valproic acid, reduce inflammatory IL-1β and TNF-α expression in rat hippocampus.
Topics: 4-Aminopyridine; Animals; Anticonvulsants; Behavior, Animal; Blotting, Western; Carbamazepine; Convulsants; DNA, Complementary; Epilepsy, Tonic-Clonic; Hippocampus; Interleukin-1beta; Lipopolysaccharides; Male; Polymerase Chain Reaction; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha; Valproic Acid; Vinca Alkaloids | 2014 |
Regulation of P2X7 receptor function of neural progenitor cells in the hippocampal subgranular zone by neuronal activity in the dentate gyrus.
Topics: 4-Aminopyridine; Action Potentials; Adenosine Triphosphate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Dentate Gyrus; Female; Gabapentin; Male; Mice; Muscimol; N-Methylaspartate; Neural Stem Cells; Neurons; Phenytoin; Receptors, Purinergic P2X7; Tetrodotoxin; Valproic Acid | 2018 |