valproic acid has been researched along with 2,2,3,3-tetramethylcyclopropane carboxamide in 7 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (85.71) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bialer, M; Sobol, E; Yagen, B | 1 |
| Bialer, M; Finnell, RH; Pessah, N; Wlodarczyk, B; Yagen, B | 1 |
| Bialer, M; Isoherranen, N; Levy, RH; White, HS; Woodhead, JH; Yagen, B | 1 |
| Aoki, Y; Bialer, M; Fujiwara, M; Okada, A; Onishi, Y; Sobol, E; Yagen, B | 1 |
| Bialer, M; Shimshoni, JA; Yagen, B | 1 |
| Bialer, M; Fujiwara, M; Kaufmann, D; Okada, A; Onishi, Y; Shimshoni, JA; Yagen, B | 1 |
| Bialer, M; Finnell, RH; Hen, N; Kaufmann, D; Pessah, N; Wlodarczyk, B; Yagen, B | 1 |
7 other study(ies) available for valproic acid and 2,2,3,3-tetramethylcyclopropane carboxamide
| Article | Year |
|---|---|
Tetramethylcyclopropyl analogue of a leading antiepileptic drug, valproic acid. Synthesis and evaluation of anticonvulsant activity of its amide derivatives.
Topics: Animals; Anticonvulsants; Convulsants; Cyclopropanes; Electroshock; Mice; Pentylenetetrazole; Polyunsaturated Alkamides; Rats; Seizures; Species Specificity; Structure-Activity Relationship; Urea; Valproic Acid | 2004 |
Alpha-fluoro-2,2,3,3-tetramethylcyclopropanecarboxamide, a novel potent anticonvulsant derivative of a cyclic analogue of valproic acid.
Topics: Abnormalities, Drug-Induced; Animals; Anticonvulsants; Cyclopropanes; Epilepsy; Male; Mice; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Valproic Acid | 2009 |
Metabolism of a new antiepileptic drug, N-methyl-tetramethylcyclopropanecarboxamide, and anticonvulsant activity of its metabolites.
Topics: Amides; Animals; Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Behavior, Animal; Biotransformation; Brain; Brain Chemistry; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Cyclopropanes; Cytochrome P-450 CYP2A6; Cytochrome P-450 CYP2C19; Dose-Response Relationship, Drug; Electroshock; Gas Chromatography-Mass Spectrometry; Humans; Hydroxylation; In Vitro Techniques; Male; Mice; Microsomes, Liver; Mixed Function Oxygenases; Pentylenetetrazole; Seizures; Valproic Acid | 2004 |
Teratology study of derivatives of tetramethylcyclopropyl amide analogues of valproic acid in mice.
Topics: Abnormalities, Drug-Induced; Amides; Animals; Body Weight; Cesarean Section; Cyclopropanes; Female; Fetus; Mice; Pregnancy; Skeleton; Teratology; Urea; Valproic Acid | 2006 |
Synthesis and anticonvulsant activity of aromatic tetramethylcyclopropanecarboxamide derivatives.
Topics: Administration, Oral; Amides; Animals; Anticonvulsants; Cyclopropanes; Electroshock; Isoxazoles; Mice; Motor Activity; Rats; Seizures; Sulfonamides; Urea; Valproic Acid; Zonisamide | 2008 |
Tetramethylcyclopropyl analogue of the leading antiepileptic drug, valproic acid: evaluation of the teratogenic effects of its amide derivatives in NMRI mice.
Topics: Abnormalities, Drug-Induced; Amides; Animals; Anticonvulsants; Benzenesulfonamides; Cyclopropanes; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Epilepsy; Female; Male; Mice; Mice, Inbred Strains; Pregnancy; Structure-Activity Relationship; Sulfonamides; Thiadiazoles; Valproic Acid | 2008 |
Comparative pharmacodynamic and pharmacokinetic analysis of two anticonvulsant halo derivatives of 2,2,3,3-tetramethylcyclopropanecarboxamide, an amide of a cyclic analog of valproic acid.
Topics: Abnormalities, Drug-Induced; Amides; Analgesics; Animals; Anticonvulsants; Cyclopropanes; Disease Models, Animal; Epilepsy; Humans; Mice; Neural Tube Defects; Pain; Pentylenetetrazole; Rats; Valproic Acid | 2010 |