valproic acid has been researched along with 1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (7.69) | 18.2507 |
| 2000's | 5 (38.46) | 29.6817 |
| 2010's | 6 (46.15) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Dingermann, T; Tillner, J; Winckler, T | 1 |
| Cheng, L; Harwood, AJ; Mudge, AW; Williams, RS | 1 |
| Adley, K; Boeckeler, K; Jenkins, A; Jin, T; Williams, RS; Xu, X | 1 |
| Bialer, M; Dalton, EC; Ewan, K; Eyal, S; Harwood, AJ; Jenkins, A; Pessah, N; Shimshoni, JA; Williams, RS; Yagen, B | 1 |
| Adley, KE; Jin, T; Lee, VW; Maniak, M; Müller-Taubenberger, A; Pawolleck, N; Sihra, TS; Wiedemann, C; Williams, RS; Xu, X | 1 |
| Pawolleck, N; Williams, RS | 1 |
| Brown, NA; Gordienko, D; Kelemen, R; Klein, PS; Shah, R; Terbach, N; Wilkinson, CJ; Williams, RS | 1 |
| Bialer, M; Chang, P; Deranieh, RM; Dham, M; Greenberg, ML; Hoeller, O; Orabi, B; Shimshoni, JA; Walker, MC; Williams, RS; Yagen, B | 1 |
| Chaieb, L; Eikel, D; Elphick, LM; Guschina, IA; Harwood, JL; Nau, H; Pawolleck, N; Plant, NJ; Williams, RS | 1 |
| Walker, MC; Williams, RS | 2 |
| Kelly, E; Sharma, D; Wilkinson, CJ; Williams, RSB | 1 |
| Baines, RP; Thompson, CRL; Wolton, K | 1 |
2 review(s) available for valproic acid and 1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone
| Article | Year |
|---|---|
The search for better epilepsy treatments: from slime mould to coconuts.
Topics: Animals; Anticonvulsants; Cocos; Dictyostelium; Drug Discovery; Epilepsy; Humans; Valproic Acid | 2013 |
New experimental therapies for status epilepticus in preclinical development.
Topics: Animals; Anticonvulsants; Dictyostelium; Diet, Ketogenic; Drug Evaluation, Preclinical; Humans; Phosphatidylinositols; Signal Transduction; Status Epilepticus; Therapies, Investigational; Valproic Acid | 2015 |
11 other study(ies) available for valproic acid and 1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone
| Article | Year |
|---|---|
Developmentally regulated promoters from Dictyostelium discoideum as molecular markers for testing potential teratogens.
Topics: Animals; Anticonvulsants; beta-Galactosidase; Biomarkers; Dictyostelium; Genes, Bacterial; Teratogens; Toxicity Tests; Transformation, Genetic; Valproic Acid | 1996 |
A common mechanism of action for three mood-stabilizing drugs.
Topics: Animals; Animals, Newborn; Antimanic Agents; Bipolar Disorder; Calcium-Calmodulin-Dependent Protein Kinases; Carbamazepine; Cell Aggregation; Chemotaxis; Dictyostelium; Ganglia, Spinal; Genes, Protozoan; Glycogen Synthase Kinases; Growth Cones; Histone Deacetylase Inhibitors; Histone Deacetylases; Hydroxamic Acids; Inositol 1,4,5-Trisphosphate; Lithium; Mice; Mutation; Neurons, Afferent; Rats; Signal Transduction; Valproic Acid | 2002 |
The neuroprotective agent, valproic acid, regulates the mitogen-activated protein kinase pathway through modulation of protein kinase A signalling in Dictyostelium discoideum.
Topics: Animals; Anticonvulsants; Cyclic AMP-Dependent Protein Kinases; Dictyostelium; Enzyme Activation; Enzyme Inhibitors; Fluorescence Resonance Energy Transfer; Glycogen Synthase Kinases; Humans; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase Kinases; Neuroprotective Agents; Protozoan Proteins; Receptors, Cyclic AMP; Valproic Acid | 2006 |
The effects of central nervous system-active valproic acid constitutional isomers, cyclopropyl analogs, and amide derivatives on neuronal growth cone behavior.
Topics: Animals; Anticonvulsants; Cells, Cultured; Dictyostelium; Ganglia, Spinal; Growth Cones; Inositol 1,4,5-Trisphosphate; Rats; Rats, Sprague-Dawley; Signal Transduction; Valproic Acid; Wnt Proteins | 2007 |
Attenuation of phospholipid signaling provides a novel mechanism for the action of valproic acid.
Topics: Animals; Anticonvulsants; Chemotaxis; Dictyostelium; Endocytosis; Enzyme Inhibitors; Exocytosis; Humans; Inositol 1,4,5-Trisphosphate; Phosphatidylinositol 3-Kinases; Phospholipids; Protozoan Proteins; Rats; Recombinant Fusion Proteins; Signal Transduction; Valproic Acid | 2007 |
Quantifying in vivo phosphoinositide turnover in chemotactically competent Dictyostelium cells.
Topics: Chemotaxis; Chromatography, Thin Layer; Dictyostelium; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Valproic Acid | 2009 |
Identifying an uptake mechanism for the antiepileptic and bipolar disorder treatment valproic acid using the simple biomedical model Dictyostelium.
Topics: Animals; Biological Transport, Active; Cells, Cultured; Dictyostelium; Hydrogen-Ion Concentration; Membrane Transport Proteins; Substrate Specificity; Valproic Acid; Xenopus laevis; Zebrafish | 2011 |
The antiepileptic drug valproic acid and other medium-chain fatty acids acutely reduce phosphoinositide levels independently of inositol in Dictyostelium.
Topics: Animals; Anticonvulsants; Dictyostelium; Disease Models, Animal; Dose-Response Relationship, Drug; Epilepsy; Inositol; Models, Biological; Mutation; Phosphatidylinositol 3-Kinases; Phosphatidylinositols; Rats; Signal Transduction; Time Factors; Valproic Acid | 2012 |
Conserved valproic-acid-induced lipid droplet formation in Dictyostelium and human hepatocytes identifies structurally active compounds.
Topics: Cell Line; Dictyostelium; Fatty Acids; Fatty Liver; Hepatocytes; Humans; Inositol; Kinetics; Lipid Metabolism; Models, Biological; Species Specificity; Teratogens; Valproic Acid | 2012 |
Diacylglycerol kinase (DGKA) regulates the effect of the epilepsy and bipolar disorder treatment valproic acid in
Topics: Amino Acid Sequence; Anticonvulsants; Bipolar Disorder; Diacylglycerol Kinase; Dictyostelium; Diglycerides; Epilepsy; Green Fluorescent Proteins; Lithium; Models, Biological; Mutation; Valproic Acid | 2018 |
Dictyostelium discoideum: An Alternative Nonanimal Model for Developmental Toxicity Testing.
Topics: Animals; Dictyostelium; Mutation; Reproduction; Toxicity Tests; Valproic Acid | 2021 |