valinomycin has been researched along with 18-crown-6* in 1 studies
1 other study(ies) available for valinomycin and 18-crown-6
Article | Year |
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Valinomycin binds stoichiometrically to cytochrome c oxidase and changes its structure and function.
Valinomycin binds to soluble and reconstituted cytochrome c oxidase (COX) in a stoichiometric manner, as shown by a spectral shift of the oxidized gamma-band. No spectral change is found with nigericin or 18-crown-6 and in the absence of potassium ions. Titration of the proton pumping activity of reconstituted COX with valinomycin reached a maximum of H+/e- - 0.73 after addition of 1 mole of valinomycin per mole of reconstituted COX. It is concluded that K+-translocation in proton-pumping COX vesicles occurs via enzyme-bound valinomycin. Topics: Animals; Cattle; Crown Ethers; Electron Transport Complex IV; Ethers, Cyclic; Hydrogen-Ion Concentration; Ion Channels; Liposomes; Membrane Potentials; Myocardium; Nigericin; Potassium; Protons; Spectrophotometry; Valinomycin | 1989 |