valine has been researched along with quinoxalines in 171 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (5.85) | 18.7374 |
| 1990's | 9 (5.26) | 18.2507 |
| 2000's | 66 (38.60) | 29.6817 |
| 2010's | 78 (45.61) | 24.3611 |
| 2020's | 8 (4.68) | 2.80 |
| Authors | Studies |
|---|---|
| Dubner, R; Hylden, JL; Ren, K; Ruda, MA; Williams, GM | 1 |
| Crunelli, V; Emri, Z; Juhász, G; Kékesi, K; Soltesz, I | 1 |
| Doi, K; Matsunaga, T; Tsumoto, T | 1 |
| Buckley, KS; Collins, GG | 1 |
| Dingledine, R; Kleckner, NW; Verdoorn, TA | 1 |
| Jones, RS; Lambert, JD | 1 |
| Brodbelt, AR; Garthwaite, J | 1 |
| Collingridge, GL; Davies, SN | 1 |
| Choi, DW; Hartley, DM | 1 |
| Evans, RH; Long, SK | 1 |
| Frenk, H; Liban, A; Teichberg, VI; Urca, G | 1 |
| Joly, M; Lynch, G; Muller, D | 1 |
| Gerchakov, S; Schultz, HP | 1 |
| Bennett, JP; Richard, MG | 1 |
| Bartlett, E; Oliver, DL; Peruzzi, D; Smith, PH | 1 |
| Furukawa, K; Holtsberg, FW; Keller, JN; Mattson, MP; Steiner, MR; Steiner, SM | 1 |
| Gatherer, M; Sundstrom, LE | 1 |
| Diao, L; Dunwiddie, TV; Finger, TE; Smeraski, CA | 1 |
| Cowan, AI; Field, AC; Redman, SJ; Stricker, C | 1 |
| Bennett, AD; Everhart, AW; Hulsebosch, CE | 1 |
| Cohen, I; Miles, R | 1 |
| Kötter, R; Luhmann, HJ; Staiger, JF; Zilles, K | 1 |
| Bertram, EH; Mangan, PS; Scott, CA; Williamson, JM | 1 |
| Gyermek, L; Hanaoka, K; Kawasaki-Yatsugi, S; Lee, C; Nishiyama, T; Yamaguchi, T | 1 |
| Hu, JY; Zhao, ZQ | 1 |
| Glick, SD; Maisonneuve, IM; Shoblock, JR; Sullivan, EB | 1 |
| Farkas, S; Kocsis, P; Szombathelyi, Z; Tarnawa, I | 1 |
| Albers, HE; Fukuhara, C; Paul, KN; Tosini, G | 1 |
| Goldin, M; Segal, M | 1 |
| Akaike, A; Kaneko, S; Katsuki, H; Kume, T; Nishikawa, H; Sugimoto, H; Taguchi, R; Terauchi, T; Yonaga, M | 1 |
| Castellano, C; Costantini, VJ; De Leonibus, E; Ferretti, V; Mele, A; Oliverio, A | 1 |
| Kang-Park, MH; Moore, SD; Wilson, WA | 1 |
| Billups, B; Forsythe, ID; Hamann, M | 1 |
| Feldman, S; Weidenfeld, J | 1 |
| Bancroft, WJ; Beazley, LD; Dunlop, SA; Rodger, J; Stirling, RV; Symonds, AC; Tee, LB | 1 |
| Gentet, LJ; Ulrich, D | 1 |
| Häusser, M; Nelson, SB; Sjöström, PJ; Turrigiano, GG; Watt, AJ | 1 |
| Lin, TB | 1 |
| Hartley, DM; Selkoe, DJ; Walsh, DM; Ye, C | 1 |
| Beierlein, M; Connors, BW; Gibson, JR | 1 |
| Barde, YA; Bibel, M; Goetz, M; Korte, M; Richter, J; Schrenk, K; Staiger, V; Tucker, KL | 1 |
| Hull, C; von Gersdorff, H | 1 |
| Kanno, T; Nagata, T; Nishizaki, T; Tanaka, A; Yaguchi, T; Yamamoto, S | 1 |
| Jewiarz, J; Keller, U; Laubinger, W; Pfennig, F; Schauwecker, F; Schlumbohm, W; Schmoock, G | 1 |
| Carr, CE; MacLeod, KM | 1 |
| Hirai, S; Maruyama, T; Ruthazer, ES; Uesaka, N; Yamamoto, N | 1 |
| Komatsu, Y; Takada, N; Yanagawa, Y | 1 |
| McKay, BE; Mehaffey, WH; Molineux, ML; Turner, RW | 1 |
| Bramley, JR; Dudek, FE; Pickard, GE; Sollars, PJ | 1 |
| Holopainen, IE; Korpi, ER; Kukko-Lukjanov, TK; Lindroos, MM; Lovinger, D; Soini, SL | 1 |
| Bevilaqua, LR; Cammarota, M; Izquierdo, I; Köhler, C; Medina, JH | 1 |
| Knöpfel, T; Mutoh, H; Yuan, Q | 1 |
| Barde, YA; Bonhoeffer, T; Korte, M; Rösch, H; Schweigreiter, R | 1 |
| Gruol, DL; Nelson, TE; Ur, CL | 1 |
| Akasu, T; Gu, JW; Hasuo, H; Takeya, M | 1 |
| Gall, CM; Lin, CY; Lynch, G | 1 |
| Cronberg, T; Jensen, K; Rytter, A; Wieloch, T | 1 |
| Helmchen, F; Nimmerjahn, A; Sarkisov, DV; Sullivan, MR; Wang, SS | 1 |
| Hamaue, N; Jia, Y; Sumikawa, K; Yamazaki, Y | 1 |
| Laute, MA; Manto, M; Pandolfo, M | 1 |
| Baudry, M; Zhou, M | 1 |
| Auberson, YP; Izumi, Y; Zorumski, CF | 1 |
| Yonehara, N; Yoshimura, M | 1 |
| Grossman, Y; Mor, A | 1 |
| Richter, A; Sander, SE | 1 |
| Gutiérrez, R; Heinemann, U; Romo-Parra, H; Treviño, M | 1 |
| Fukushima, M; Kano, T; Katayama, Y; Koshinaga, M; Suma, T | 1 |
| King, MA; López-Hernández, GY; Meyer, EM; Papke, RL; Ren, K; Thinschmidt, JS | 1 |
| Ibata, K; Sun, Q; Turrigiano, GG | 1 |
| Decker, MW; Man, K; Parikh, V; Sarter, M | 1 |
| Ben-Ari, Y; Holmes, GL; Ivanov, A; Khazipov, R; Minlebaev, M; Represa, A; Rheims, S; Zilberter, Y | 1 |
| Bryan, S; Dawson, SJ; Fox, KR; Hampshire, AJ; Malkinson, JP; Paumier, D; Rusling, DA; Searcey, M | 1 |
| Medd, AM; Simmons, MA; Sobotka-Briner, CD | 1 |
| Fetcho, JR; Koh, IY; Lindquist, WB; Masino, MA; McLean, DL | 1 |
| Ackman, JB; Aniksztejn, L; Becq, H; Ben-Ari, Y; Cardoso, C; Crépel, V; Pellegrino, C; Represa, A | 1 |
| Di, S; Franco, A; Maxson, MM; Tasker, JG | 1 |
| Cohen, D; Segal, M | 1 |
| Avoli, M; de Curtis, M; Uva, L | 1 |
| Kovacs, FE; Szabo, B; Urbanski, MJ | 1 |
| Bortone, D; Polleux, F | 1 |
| Blankenship, AG; Copenhagen, DR; Edwards, RH; Feller, MB; Ford, KJ; Johnson, J; Seal, RP | 1 |
| Connors, JM; Coolen, LM; Goodman, RL; Hileman, SM; Lehman, MN; McManus, CJ; Singh, SR | 1 |
| Dieni, C; Frondaroli, A; Grassi, S; Pettorossi, VE; Scarduzio, M | 1 |
| Diabira, D; Ferrand, N; Fiorentino, H; Gaiarsa, JL; Kuczewski, N; Pangalos, MN; Porcher, C | 1 |
| He, XH; Justice, JA; Peng, BW; Sanchez, RM; Zhang, K | 1 |
| Hughes, DI; Nagy, GG; Polgár, E; Riddell, JS; Todd, AJ; Watanabe, M; Yasaka, T | 1 |
| Bisogno, T; Brussaard, AB; Burnashev, N; Canto, CB; Di Marzo, V; Heistek, TS; Lodder, JC; Mansvelder, HD; Min, R; Testa-Silva, G | 1 |
| Hamann, M; Kreil, A; Richter, A; Sander, SE | 1 |
| Maren, S; Zimmerman, JM | 1 |
| Gire, DH; Pandipati, S; Schoppa, NE | 1 |
| Ehlers, MD; Lee, MC; Yasuda, R | 1 |
| Canning, BJ; Mori, N | 1 |
| Doengi, M; Gaburro, S; Häring, M; Kamprath, K; Lutz, B; Pape, HC; Romo-Parra, H | 1 |
| Plenz, D; Roy, R; Shew, WL; Yang, H; Yu, S | 1 |
| Chen, G; Ebner, TJ; Gao, W; Wang, X | 1 |
| Adam, C; Baulac, M; Clemenceau, S; Cohen, I; Huberfeld, G; Le Van Quyen, M; Menendez de la Prida, L; Miles, R; Pallud, J | 1 |
| Gutiérrez, R; Treviño, M; Vivar, C | 1 |
| Andresen, MC; Jin, YH | 1 |
| Bassani, S; Benfante, R; Billuart, P; Chelly, J; Dorseuil, O; Gianfelice, A; Khelfaoui, M; Lagneaux, C; Passafaro, M; Sala, C; Valnegri, P | 1 |
| Dieni, CV; Markwardt, SJ; Overstreet-Wadiche, L; Wadiche, JI | 1 |
| Chavis, P; Farrugia, F; Garenne, A; Le Masson, G; Manzoni, OJ; Marsicano, G; Piet, R | 1 |
| Boiti, C; Brecchia, G; Dieni, CV; Frondaroli, A; Grassi, S; Pettorossi, VE; Scarduzio, M | 1 |
| Cyr, M; Dontigny, E; Massicotte, G; Patenaude, C | 1 |
| Behnisch, T; Chen, Y; Huang, Y; Zhu, G; Zhuang, Y | 1 |
| Fraser, SE; Huss, D; Kashima, DT; Lansford, R; Poynter, G; Rubel, EW; Sanchez, JT; Schecterson, L; Seidl, AH; Tabor, KM; Wang, Y | 1 |
| Brill, J; Bryant, A; Huguenard, JR; Lacey, CJ | 1 |
| Crawford, DC; Jiang, X; Mennerick, S; Taylor, A | 1 |
| Chen, S; Mohajerani, MH; Murphy, TH; Xie, Y | 1 |
| Colbert, CM; Eskin, A; Pita-Almenar, JD; Zou, S | 1 |
| Chen, SR; Cheng, PW; Cheng, WH; Hong, LZ; Tseng, CJ; Wang, LL | 1 |
| Devidze, N; Eilertson, K; Ho, K; Kravitz, AV; Kreitzer, AC; Mucke, L; Sanchez, PE; Suberbielle, E; Wang, X | 1 |
| Maccaferri, G; Quattrocolo, G | 1 |
| Cui, R; Dong, Y; Huang, YH; Ishikawa, M; Lee, BR; Liu, L; Neumann, PA; Otaka, M; Schlüter, OM | 1 |
| Bonci, A; Cho, SL; de Lecea, L; Deisseroth, K; Kempadoo, KA; Leinninger, GM; Magnani, F; Myers, MG; Stuber, GD; Tourino, C; Zhang, F | 1 |
| Baghdadwala, MI; Ferguson, EV; Kottick, A; Wilson, RJ | 1 |
| Bean, BP; Yamada-Hanff, J | 1 |
| Mozrzymas, JW; Wójtowicz, T | 1 |
| Prosser, RA; Yamada, Y | 1 |
| Beloeil, JC; Bennaï, S; Bizot, JC; Collin, T; Créau, N; Dierssen, M; Hérault, Y; Jouhault, Q; Lopes Pereira, P; Luilier, S; Masini, D; Même, S; Mouton-Liger, F; Paly, E; Sahún, I; Thomas, S | 1 |
| Barría, A; Rubel, EW; Seidl, AH | 1 |
| Bosking, WH; Elyada, YM; Fitzpatrick, D; Huang, X; Walker, T | 1 |
| Adam, F; Blakemore, DC; Brimage, RA; Chiva, JY; Dayal, S; Gardner, I; Glen, R; Halstead, R; Hay, D; Milbank, J; Nichols, C; Paradowski, M; Pickford, C; Pike, A; Pryde, DC; Shaw, S; Smith-Burchnell, C; Tran, TD; Wakenhut, F; Watson, L; Webster, R; Westby, M; Wilson, CP | 1 |
| Borgia, G; Buonomo, AR; Gentile, I; Zappulo, E | 1 |
| Booth, R; Kim, H | 1 |
| Avchalumov, Y; Bode, C; Hamann, M; Kirschstein, T; Köhling, R; Porath, K; Richter, A; Richter, F; Sander, SE | 1 |
| Cohen, AB; Jone, A; Kritzer, MF; Locklear, MN | 1 |
| Gale, SD; Murphy, GJ | 1 |
| Dumon, C; Ferrand, N; Friedel, P; Gaiarsa, JL; Medina, I; Porcher, C; Riffault, B; Thalman, C | 1 |
| Adelson, PD; Anderson, T; Nichols, J; Perez, R; Wu, C | 1 |
| Barik, J; Bethus, I; Chafai, M; Kootar, S; Lanté, F; Marie, H; Mouska, X; Pereira, AR; Raymond, EF | 1 |
| Anderson, CT; Borges, K; Joshi, A; Middleton, JW; Shepherd, GM; Suter, BA; Tzounopoulos, T | 1 |
| Brooks-Kayal, A; Carlsen, J; Cea-Del Rio, CA; Cruz Del Angel, Y; González, MI; Grabenstatter, HL; Huntsman, MM; Laoprasert, RP; White, AM | 1 |
| Behrens, CJ; Fano, S; Gebhardt, C; Heinemann, U; Huchzermeyer, C; Jarosch, MS; Ul Haq, R | 1 |
| Bazelot, M; Blaesse, P; Capogna, M; Goedecke, L; Jüngling, K; Pape, HC | 1 |
| Chen, K; Nakauchi, S; Su, H; Sumikawa, K; Tanimoto, S | 1 |
| Albers, EH; Keshavarzi, S; Power, JM; Sah, P; Sullivan, RK | 1 |
| Hubbard, H; Lawitz, E; Vizuete, J | 1 |
| Asselah, T; Boyer, N; Marcellin, P; Martinot-Peignoux, M; Saadoun, D | 1 |
| Béïque, JC; Lee, KF; Soares, C; Thivierge, JP | 1 |
| Ichitani, Y; Iwamura, E; Yamada, K | 1 |
| Connors, BW; Neske, GT | 1 |
| Klyachko, VA; Wahlstrom-Helgren, S | 1 |
| Luo, F; Sun, X; Tang, H; Zheng, J | 1 |
| Martina, M; Pollema-Mays, SL; Radzicki, D; Sanz-Clemente, A | 1 |
| Lim, SG | 1 |
| Jacobs, KM; Jin, X; Povlishock, JT; Vascak, M | 1 |
| Alston, S; Di Bisceglie, AM; Evon, DM; Fried, MW; Golin, CE; Lim, JK; Lok, AS; Nelson, DR; Reau, N; Reddy, KR; Reeve, B; Sarkar, S; Sterling, RK; Stewart, P | 1 |
| Frazier, CJ; Krause, EG; Pati, D | 1 |
| Kato, T; Kawano, T; Sato, H; Toyoda, H; Yin, DX | 1 |
| Gu, K; Jiang, B; Li, Y; Ma, P; Ma, X; Song, T; Wang, C; Yang, Y; Zhao, J | 1 |
| Alves, K; Atarashi, T; Burroughs, M; Chayama, K; Eguchi, Y; Karino, Y; Kato, K; Kawakami, Y; Krishnan, P; Kumada, H; Naganuma, A; Oberoi, RK; Pilot-Matias, TJ; Pugatch, DL; Redman, R; Sato, K; Seike, M; Suzuki, F; Takei, Y; Watanabe, T; Xie, W; Yoshiji, H | 1 |
| Blümcke, I; Groemer, TW; Hackenbracht, J; Jablonski, J; Kiese, K; Kobow, K; Kornhuber, J; Wrosch, JK | 1 |
| Collingridge, GL; Jia, Z; Leung, C; Liu, A; Meng, Y; Park, P; Qi, J; Xia, S; Xie, W; Zhou, Z | 1 |
| Asatryan, A; Asselah, T; Bourlière, M; Bruck, R; Chuang, WL; Dore, GJ; Feld, JJ; Felizarta, F; Flamm, S; Flisiak, R; Foster, GR; Fu, B; Fuster, F; Gane, E; Kaita, K; Kort, J; Kwo, P; Lin, CW; Liu, R; Mensa, FJ; Ng, TI; Paik, SW; Pilot-Matias, T; Pol, S; Poordad, F; Puoti, M; Roberts, SK; Ruane, PJ; Sepulveda-Arzola, G; Soto-Malave, R; Stedman, CA; Tam, E; Trinh, R; Vargas, HE; Vierling, J; Wang, S; Wedemeyer, H; Zeuzem, S | 1 |
| Antic, SD; McKimm, EJ; Milosevic, MM; Singh, MB; White, JA | 1 |
| Bhandiwad, AA; Raible, DW; Rubel, EW; Sisneros, JA | 1 |
| Chen, P; Liu, Q; Ma, A | 1 |
| Bondin, M; Cacoub, P; Fabrizi, F; Negro, F | 1 |
| Cenderello, G; Di Biagio, A; Taramasso, L | 1 |
| Baba, M; Kawagishi, N; Kimura, M; Maehara, O; Morikawa, K; Nakai, M; Nakamura, A; Natsuizaka, M; Ogawa, K; Ohara, M; Sakamoto, N; Shigesawa, T; Shimazaki, T; Sho, T; Suda, G; Suzuki, K; Umemura, M | 1 |
| Althoff, CE; Bergfeld, L; Brakemeier, S; Budde, K; Duerr, M; Eckardt, KU; Glander, P; Halleck, F; Lehner, LJ; Marticorena Garcia, SR; Sack, I; Schrezenmeier, EV | 1 |
| Bukh, J; Dietz, J; Fahnøe, U; Filskov, J; Fourati, S; Ghanem, L; Gottwein, JM; Humes, D; Jensen, SB; Krarup, H; Pawlotsky, JM; Pedersen, MS; Pham, LV; Pihl, AF; Ramirez, S; Sarrazin, C; Schønning, K; Serre, SBN; Sølund, CS; Tang, Q; Weis, N | 1 |
| Amador, J; Di Bisceglie, AM; Evon, DM; Fried, MW; Golin, CE; Lim, JK; Lok, AS; Nelson, DR; Rajender Reddy, K; Reau, N; Reeve, BB; Sarkar, S; Serper, M; Sterling, RK; Stewart, PW | 1 |
| Aikata, H; Chayama, K; Hiramatsu, A; Imamura, M; Kawaoka, T; Morio, K; Murakami, E; Nakahara, T; Ohya, K; Tsuge, M; Yamauchi, M | 1 |
| Agarwal, K; Bestwick, J; Drysdale, K; Elsharkawy, AM; Forton, D; Foster, GR; Gelson, W; Mahomed, F; Mutimer, D; Ntuli, Y; Townley, C | 1 |
| Bing, YH; Chu, CP; Cui, BR; Cui, LN; Li, BX; Qiu, DL; Zhang, GJ; Zhang, XY | 1 |
| Deguchi, A; Fujita, K; Himoto, T; Iwama, H; Kobara, H; Masaki, T; Mimura, S; Morishita, A; Nakahara, M; Nomura, T; Oryu, M; Oura, K; Sakamoto, T; Shimotohno, K; Tadokoro, T; Takuma, K; Tani, J; Tsutsui, K; Wakita, T; Yoneyama, H | 1 |
| Chen, SC; Cheng, TS; Chuang, WL; Dai, CY; Hsieh, PH; Huang, CF; Huang, CI; Huang, JF; Liang, PC; Lin, ZY; Yeh, ML; Yu, ML | 1 |
| Chen, H; Li, C; Liang, J; Tian, J; Xiang, H | 1 |
| Darling, JM; Di Bisceglie, A; Dong, M; Evon, DM; Fishbein, DA; Fried, MW; Hinestrosa, F; Horne, PM; Khalili, M; Kixmiller, S; Lok, AS; Michael, L; Moon, JS; Morelli, G; Muir, AJ; Nelson, DR; Pearlman, B; Peter, J; Rajender Reddy, K; Segal, JB; Sherman, KE; Shiffman, ML; Sloan, A; Stewart, PW; Sulkowski, MS; Vainorius, M; Wadsworth, S | 1 |
| Bough, R; Dayan, FE | 1 |
7 review(s) available for valine and quinoxalines
| Article | Year |
|---|---|
Interferon-free therapies for chronic hepatitis C: toward a hepatitis C virus-free world?
Topics: 2-Naphthylamine; Amides; Anilides; Antiviral Agents; Benzofurans; Carbamates; Clinical Trials as Topic; Cyclopropanes; Disease Eradication; Drug Combinations; Hepacivirus; Hepatitis C; Humans; Imidazoles; Isoquinolines; Lactams, Macrocyclic; Macrocyclic Compounds; Proline; Pyrrolidines; Quinoxalines; Ribavirin; Sofosbuvir; Sulfonamides; Uracil; Uridine Monophosphate; Valine | 2014 |
Next-Generation Regimens: The Future of Hepatitis C Virus Therapy.
Topics: Amides; Antiviral Agents; Benzazepines; Benzofurans; Carbamates; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Cyclopropanes; Drug Discovery; Drug Therapy, Combination; Forecasting; Hepacivirus; Hepatitis C, Chronic; Heterocyclic Compounds, 4 or More Rings; Humans; Imidazoles; Indoles; Isoquinolines; MicroRNAs; Molecular Targeted Therapy; Nucleic Acid Synthesis Inhibitors; Protease Inhibitors; Pyrrolidines; Quinoxalines; RNA, Viral; Sofosbuvir; Sulfonamides; Valine; Viral Nonstructural Proteins | 2015 |
Direct-acting antivirals for the treatment of hepatitis C virus infection: optimizing current IFN-free treatment and future perspectives.
Topics: 2-Naphthylamine; Amides; Anilides; Antiviral Agents; Benzimidazoles; Benzofurans; Carbamates; Cyclopropanes; Drug Therapy, Combination; Female; Fluorenes; Genotype; Hepacivirus; Hepatitis C, Chronic; Heterocyclic Compounds, 4 or More Rings; Humans; Imidazoles; Lactams, Macrocyclic; Macrocyclic Compounds; Proline; Protease Inhibitors; Quinoxalines; Sofosbuvir; Sulfonamides; Uracil; Valine; Viral Nonstructural Proteins | 2016 |
HCV management in resource-constrained countries.
Topics: Aminoisobutyric Acids; Antiviral Agents; Australia; Benzimidazoles; Carbamates; Continuity of Patient Care; Cyclopropanes; Drug Combinations; Drug Therapy, Combination; Drugs, Generic; Fluorenes; Genotype; Hepacivirus; Hepatitis C; Heterocyclic Compounds, 4 or More Rings; Humans; Imidazoles; Lactams, Macrocyclic; Leucine; Liver Cirrhosis; Proline; Pyrrolidines; Quinoxalines; Ribavirin; Risk Factors; Sofosbuvir; Sulfonamides; Valine | 2017 |
Expert opinion on the management of renal manifestations of chronic HCV infection.
Topics: 2-Naphthylamine; Amides; Aminoisobutyric Acids; Anilides; Antiviral Agents; Benzimidazoles; Benzofurans; Carbamates; Cyclopropanes; Disease Management; Drug Therapy, Combination; Expert Testimony; Hepacivirus; Hepatitis C, Chronic; Humans; Imidazoles; Lactams, Macrocyclic; Leucine; Macrocyclic Compounds; Practice Guidelines as Topic; Proline; Pyrrolidines; Quinoxalines; Renal Insufficiency, Chronic; Risk Factors; Ritonavir; Sulfonamides; Uracil; Valine | 2018 |
Treatment of hepatitis C virus genotype 4 in the DAA era.
Topics: Aminoisobutyric Acids; Anilides; Antiviral Agents; Carbamates; Clinical Trials as Topic; Cyclopropanes; Drug Therapy, Combination; Genotype; Hepacivirus; Hepatitis C, Chronic; Heterocyclic Compounds, 4 or More Rings; Humans; Interferons; Lactams, Macrocyclic; Leucine; Macrocyclic Compounds; Proline; Quinoxalines; Ribavirin; Sofosbuvir; Sulfonamides; Sustained Virologic Response; Valine | 2018 |
Evolutionary Pathways to Persistence of Highly Fit and Resistant Hepatitis C Virus Protease Inhibitor Escape Variants.
Topics: 2-Naphthylamine; Aminoisobutyric Acids; Anilides; Antiviral Agents; Benzimidazoles; Carbamates; Cyclopropanes; Denmark; Drug Resistance, Viral; Drug Therapy, Combination; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Lactams, Macrocyclic; Leucine; Male; Prognosis; Proline; Protease Inhibitors; Pyrrolidines; Quinoxalines; Sulfonamides; Uracil; Valine | 2019 |
4 trial(s) available for valine and quinoxalines
| Article | Year |
|---|---|
Efficacy and safety of glecaprevir/pibrentasvir in Japanese patients with chronic genotype 1 hepatitis C virus infection with and without cirrhosis.
Topics: Adult; Age Distribution; Aged; Aged, 80 and over; Aminoisobutyric Acids; Anilides; Antiviral Agents; Benzimidazoles; Carbamates; Cyclopropanes; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Female; Hepacivirus; Hepatitis C, Chronic; Humans; Lactams, Macrocyclic; Leucine; Liver Cirrhosis; Macrocyclic Compounds; Male; Middle Aged; Proline; Pyrrolidines; Quinoxalines; Ritonavir; RNA, Viral; Sulfonamides; Sustained Virologic Response; Valine; Viral Nonstructural Proteins | 2018 |
Glecaprevir-Pibrentasvir for 8 or 12 Weeks in HCV Genotype 1 or 3 Infection.
Topics: Adult; Aged; Aged, 80 and over; Aminoisobutyric Acids; Antiviral Agents; Benzimidazoles; Carbamates; Cyclopropanes; Drug Administration Schedule; Drug Combinations; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Imidazoles; Lactams, Macrocyclic; Leucine; Male; Middle Aged; Proline; Pyrrolidines; Quinoxalines; RNA, Viral; Sofosbuvir; Sulfonamides; Valine; Viral Load | 2018 |
A prospective study of daclatasvir and sofosbuvir in chronic HCV-infected kidney transplant recipients.
Topics: Adult; Aged; Aminoisobutyric Acids; Antiviral Agents; Biopsy, Needle; Calcineurin Inhibitors; Carbamates; Cyclopropanes; Drug Therapy, Combination; Female; Glucose Intolerance; Hepacivirus; Hepatitis C, Chronic; Heterocyclic Compounds, 4 or More Rings; Humans; Imidazoles; Kidney Failure, Chronic; Kidney Transplantation; Lactams, Macrocyclic; Leucine; Liver; Macrocyclic Compounds; Male; Middle Aged; Proline; Prospective Studies; Pyrrolidines; Quinoxalines; RNA, Viral; Salvage Therapy; Sofosbuvir; Sulfonamides; Treatment Outcome; Valine; Viral Load; Viral Nonstructural Proteins; Viremia | 2019 |
A Pragmatic, Randomized Controlled Trial of Oral Antivirals for the Treatment of Chronic Hepatitis C: The PRIORITIZE Study.
Topics: 2-Naphthylamine; Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Anilides; Antiviral Agents; Benzimidazoles; Benzofurans; Cyclopropanes; Drug Combinations; Drug Therapy, Combination; Female; Fluorenes; Follow-Up Studies; Genotyping Techniques; Hepacivirus; Hepatitis C, Chronic; Humans; Imidazoles; Lactams, Macrocyclic; Male; Middle Aged; Proline; Quinoxalines; Ribavirin; RNA, Viral; Sofosbuvir; Sulfonamides; Sustained Virologic Response; Treatment Outcome; Uracil; Valine; Young Adult | 2021 |
160 other study(ies) available for valine and quinoxalines
| Article | Year |
|---|---|
The intrathecal administration of excitatory amino acid receptor antagonists selectively attenuated carrageenan-induced behavioral hyperalgesia in rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analgesics; Analysis of Variance; Animals; Behavior, Animal; Carrageenan; Dizocilpine Maleate; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Hyperalgesia; Inflammation; Injections, Spinal; Ketamine; Kynurenic Acid; Male; Piperazines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Valine | 1992 |
Sleep-promoting action of excitatory amino acid antagonists: a different role for thalamic NMDA and non-NMDA receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cats; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Sleep; Thalamic Nuclei; Valine | 1990 |
Actions of excitatory amino acid antagonists on synaptic inputs to the rat medial vestibular nucleus: an electrophysiological study in vitro.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Brain Stem; Electric Stimulation; Electrophysiology; Evoked Potentials; Female; In Vitro Techniques; Kynurenic Acid; Male; Neural Pathways; Neurons, Afferent; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission; Valine; Vestibular Nuclei | 1990 |
Antagonism of monosynaptic excitations in the mouse olfactory cortex slice by 6,7-dinitroquinoxaline-2,3-dione.
Topics: Animals; Aspartic Acid; Cerebral Cortex; In Vitro Techniques; Male; Mice; N-Methylaspartate; Oxadiazoles; Pyramidal Tracts; Quinoxalines; Quisqualic Acid; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Neurotransmitter; Reflex, Monosynaptic; Synapses; Synaptic Transmission; Valine | 1989 |
N-methyl-D-aspartate/glycine and quisqualate/kainate receptors expressed in Xenopus oocytes: antagonist pharmacology.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Kainic Acid; N-Methylaspartate; Oocytes; Quinoxalines; Receptors, AMPA; Receptors, Glycine; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1989 |
Activation of N-methyl-D-aspartate receptors contributes to the EPSP at perforant path synapses in the rat dentate gyrus in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Electrophysiology; Evoked Potentials; Hippocampus; Picrotoxin; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1989 |
Synaptic activation of N-methyl-D-aspartate and non-N-methyl-D-aspartate receptors in the mossy fibre pathway in adult and immature rat cerebellar slices.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Aging; Animals; Cerebellum; Female; In Vitro Techniques; Male; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1989 |
Role of excitatory amino acid receptors in synaptic transmission in area CA1 of rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Anticonvulsants; Electric Stimulation; Evoked Potentials; Hippocampus; In Vitro Techniques; Neurons; Picrotoxin; Pyramidal Tracts; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses; Synaptic Transmission; Valine | 1989 |
Delayed rescue of N-methyl-D-aspartate receptor-mediated neuronal injury in cortical culture.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Calcium; Cells, Cultured; Cerebral Cortex; Glutamates; Glutamic Acid; Mice; N-Methylaspartate; Neurons; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Sodium; Valine | 1989 |
Primary afferent depolarization in the rat spinal cord is mediated by pathways utilising NMDA and non-NMDA receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Ganglia, Spinal; In Vitro Techniques; Kynurenic Acid; Neurons, Afferent; Quinoxalines; Rats; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1989 |
Absence of side-effects in the anticonvulsant action of cortically applied antagonists of N-methyl-D-aspartate.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Aspartic Acid; Dipeptides; Morphine; N-Methylaspartate; Picrotoxin; Quinoxalines; Rats; Rats, Inbred Strains; Seizures; Strychnine; Valine | 1986 |
Contributions of quisqualate and NMDA receptors to the induction and expression of LTP.
Topics: 2-Amino-5-phosphonovalerate; Animals; Electric Conductivity; Electric Stimulation; Evoked Potentials; Hippocampus; Magnesium; Male; Membrane Potentials; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses; Valine | 1988 |
Quinoxaline studies. XIV. Potential anticancer agents. Some quinoxaline amino acid and dipeptide derivatives related to quinoxaline antibiotics.
Topics: Alanine; Amino Acids; Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Dipeptides; Glycine; Leukemia L1210; Methionine; Mice; Quinoxalines; Serine; Valine | 1969 |
NMDA receptor blockade increases in vivo striatal dopamine synthesis and release in rats and mice with incomplete, dopamine-depleting, nigrostriatal lesions.
Topics: Animals; Arginine; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Excitatory Amino Acids; Male; Mice; Microdialysis; Nitroarginine; Oxidopamine; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Substantia Nigra; Valine | 1995 |
A monosynaptic GABAergic input from the inferior colliculus to the medial geniculate body in rat.
Topics: Animals; Cell Size; Electrophysiology; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Geniculate Bodies; Inferior Colliculi; Interneurons; Membrane Potentials; Microspheres; Neural Pathways; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, GABA-B; Synapses; Thalamic Nuclei; Valine | 1997 |
Lysophosphatidic acid induces a sustained elevation of neuronal intracellular calcium.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium; Calcium Channels; Cells, Cultured; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Ion Channel Gating; Lysophospholipids; Neurons; Patch-Clamp Techniques; Quinoxalines; Rats; Receptors, Glutamate; Valine | 1997 |
Mossy fibre innervation is not required for the development of kainic acid toxicity in organotypic hippocampal slice cultures.
Topics: Animals; Cell Death; Cell Survival; Hippocampus; In Vitro Techniques; Kainic Acid; Microelectrodes; Mossy Fibers, Hippocampal; N-Methylaspartate; Neural Pathways; Pyramidal Cells; Quinoxalines; Rats; Rats, Wistar; Receptors, Glutamate; Time Factors; Valine | 1998 |
NMDA and non-NMDA receptors mediate responses in the primary gustatory nucleus in goldfish.
Topics: Animals; Brain; Cerebrospinal Fluid; Electric Stimulation; Electrophysiology; Evoked Potentials; Goldfish; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Vagus Nerve; Valine | 1999 |
Analysis of NMDA-independent long-term potentiation induced at CA3-CA1 synapses in rat hippocampus in vitro.
Topics: Animals; Calcium; Cerebrospinal Fluid; Electrophysiology; Excitatory Postsynaptic Potentials; Female; Hippocampus; Long-Term Potentiation; Male; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Synapses; Valine | 1999 |
Intrathecal administration of an NMDA or a non-NMDA receptor antagonist reduces mechanical but not thermal allodynia in a rodent model of chronic central pain after spinal cord injury.
Topics: Animals; Chronic Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Hyperalgesia; Injections, Spinal; Male; Motor Activity; Pain; Physical Stimulation; Quinoxalines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Spinal Cord Injuries; Valine | 2000 |
Contributions of intrinsic and synaptic activities to the generation of neuronal discharges in in vitro hippocampus.
Topics: Action Potentials; Animals; Calibration; Excitatory Postsynaptic Potentials; Extracellular Space; Guinea Pigs; Hippocampus; In Vitro Techniques; Microelectrodes; Neurons; Patch-Clamp Techniques; Potassium; Pyramidal Cells; Quinoxalines; Receptors, AMPA; Receptors, Presynaptic; Synapses; Valine | 2000 |
Laminar characteristics of functional connectivity in rat barrel cortex revealed by stimulation with caged-glutamate.
Topics: Animals; Brain Mapping; Electrophysiology; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; In Vitro Techniques; Male; Neural Pathways; Neurons; Photic Stimulation; Photolysis; Quinoxalines; Rats; Rats, Wistar; Receptors, Glutamate; Somatosensory Cortex; Synapses; Time Factors; Valine; Vibrissae | 2000 |
Aberrant neuronal physiology in the basal nucleus of the amygdala in a model of chronic limbic epilepsy.
Topics: Action Potentials; Amygdala; Animals; Disease Models, Animal; Electric Stimulation; Epilepsy; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Kindling, Neurologic; Neural Pathways; Neurons; Phosphinic Acids; Propanolamines; Quinoxalines; Rats; Valine | 2000 |
The analgesic interaction between intrathecal clonidine and glutamate receptor antagonists on thermal and formalin-induced pain in rats.
Topics: Adrenergic alpha-Agonists; Analgesics, Non-Narcotic; Animals; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Imidazoles; Injections, Spinal; Pain; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Valine | 2001 |
Differential contributions of NMDA and non-NMDA receptors to spinal Fos expression evoked by superficial tissue and muscle inflammation in the rat.
Topics: Afferent Pathways; Animals; Cell Count; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; Immunohistochemistry; Inflammation; Male; Muscle, Skeletal; Nociceptors; Pain; Posterior Horn Cells; Proto-Oncogene Proteins c-fos; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Skin; Synaptic Transmission; Turpentine; Valine | 2001 |
Neurochemical and behavioral differences between d-methamphetamine and d-amphetamine in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Behavior, Animal; Brain Chemistry; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Homovanillic Acid; Methamphetamine; Microdialysis; Motor Activity; Nucleus Accumbens; Prefrontal Cortex; Quinoxalines; Rats; Rats, Sprague-Dawley; Time Factors; Valine | 2003 |
Participation of AMPA- and NMDA-type excitatory amino acid receptors in the spinal reflex transmission, in rat.
Topics: Action Potentials; Animals; Animals, Newborn; Anti-Anxiety Agents; Benzodiazepines; Dizocilpine Maleate; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Antagonists; In Vitro Techniques; Magnesium; Models, Neurological; Piperazines; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Reflex, Monosynaptic; Spinal Cord; Synapses; Time Factors; Valine | 2003 |
Transduction of light in the suprachiasmatic nucleus: evidence for two different neurochemical cascades regulating the levels of Per1 mRNA and pineal melatonin.
Topics: Animals; Autoradiography; Cricetinae; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Light; Male; Melatonin; Microinjections; N-Methylaspartate; Nuclear Proteins; Pineal Gland; Quinoxalines; Radioimmunoassay; RNA, Messenger; Suprachiasmatic Nucleus; Valine | 2003 |
Protein kinase C and ERK involvement in dendritic spine plasticity in cultured rodent hippocampal neurons.
Topics: Activating Transcription Factor 1; Analysis of Variance; Animals; Animals, Newborn; Cell Size; Cells, Cultured; Culture Media, Conditioned; Dendrites; DNA-Binding Proteins; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Green Fluorescent Proteins; Hippocampus; Imaging, Three-Dimensional; Immunohistochemistry; In Vitro Techniques; Luminescent Proteins; Mice; Mitogen-Activated Protein Kinases; Neuronal Plasticity; Neurons; Patch-Clamp Techniques; Protein Kinase C; Quinoxalines; Rats; Time Factors; Transcription Factors; Transfection; Valine | 2003 |
Serofendic acid prevents acute glutamate neurotoxicity in cultured cortical neurons.
Topics: Animals; Calcium; Cattle; Cell Survival; Cells, Cultured; Cerebral Cortex; Cysteine; Diterpenes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Combinations; Fetal Blood; Fetus; Ionomycin; Neurons; Neurotoxicity Syndromes; Nitric Oxide; Quinoxalines; Rats; S-Nitrosothiols; Sodium Glutamate; Time Factors; Valine | 2003 |
Distinct roles of the different ionotropic glutamate receptors within the nucleus accumbens in passive-avoidance learning and memory in mice.
Topics: Analysis of Variance; Animals; Avoidance Learning; Behavior, Animal; Excitatory Amino Acid Antagonists; Male; Memory; Mice; Nucleus Accumbens; Quinoxalines; Reaction Time; Receptors, Glutamate; Staining and Labeling; Time Factors; Valine | 2003 |
Differential actions of diazepam and zolpidem in basolateral and central amygdala nuclei.
Topics: Amygdala; Animals; Animals, Newborn; Bicuculline; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; GABA Agonists; GABA Antagonists; GABA Modulators; In Vitro Techniques; Male; Neural Inhibition; Patch-Clamp Techniques; Pyridines; Quinoxalines; Rats; Rats, Sprague-Dawley; Valine; Zolpidem | 2004 |
Non-calyceal excitatory inputs mediate low fidelity synaptic transmission in rat auditory brainstem slices.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics, Local; Animals; Animals, Newborn; Auditory Pathways; Brain Stem; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Membrane Potentials; Neurons; Patch-Clamp Techniques; Quinoxalines; Rats; Synaptic Transmission; Tetrodotoxin; Time Factors; Valine | 2003 |
Involvement of endogeneous glutamate in the stimulatory effect of norepinephrine and serotonin on the hypothalamo-pituitary-adrenocortical axis.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Agonists; Adrenocorticotropic Hormone; Analysis of Variance; Animals; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; Glutamic Acid; Hydrocortisone; Hypothalamo-Hypophyseal System; Male; Norepinephrine; Paraventricular Hypothalamic Nucleus; Phenylephrine; Pituitary-Adrenal System; Quinoxalines; Radioimmunoassay; Rats; Serotonin; Serotonin Receptor Agonists; Valine | 2004 |
Failure to form a stable topographic map during optic nerve regeneration: abnormal activity-dependent mechanisms.
Topics: Animals; Blotting, Western; Brain Mapping; Electrophysiology; Evoked Potentials, Visual; Excitatory Amino Acid Antagonists; Immunohistochemistry; Lizards; Nerve Crush; Nerve Regeneration; Optic Nerve; Optic Nerve Injuries; Quinoxalines; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Time Factors; Valine | 2003 |
Electrophysiological characterization of synaptic connections between layer VI cortical cells and neurons of the nucleus reticularis thalami in juvenile rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Cerebral Cortex; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; In Vitro Techniques; Membrane Potentials; Neural Conduction; Neural Inhibition; Neurons; Patch-Clamp Techniques; Picrotoxin; Potassium; Quinoxalines; Rats; Rats, Wistar; Synapses; Thalamic Nuclei; Valine | 2004 |
A proportional but slower NMDA potentiation follows AMPA potentiation in LTP.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Cells, Cultured; Drug Synergism; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Long-Term Potentiation; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Quinoxalines; Rats; Receptors, AMPA; Sodium Channel Blockers; Synapses; Tetrodotoxin; Time Factors; Transfection; Valine; Visual Cortex | 2004 |
Tetanization-induced pelvic-to-pudendal reflex plasticity in anesthetized rats.
Topics: Animals; Bicuculline; Decerebrate State; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; GABA-A Receptor Antagonists; Glutamic Acid; Long-Term Potentiation; N-Methylaspartate; Nervous System Physiological Phenomena; Neuronal Plasticity; Pelvis; Quinoxalines; Rats; Rats, Wistar; Reflex; Valine | 2004 |
Amyloid beta-protein induced electrophysiological changes are dependent on aggregation state: N-methyl-D-aspartate (NMDA) versus non-NMDA receptor/channel activation.
Topics: Amyloid beta-Peptides; Animals; Cells, Cultured; Drug Interactions; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Immunohistochemistry; In Vitro Techniques; Membrane Potentials; Microtubule-Associated Proteins; Neocortex; Neurons; Patch-Clamp Techniques; Protein Conformation; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Valine | 2004 |
Functional properties of electrical synapses between inhibitory interneurons of neocortical layer 4.
Topics: Analysis of Variance; Animals; Animals, Newborn; Electric Stimulation; Electrodes; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Gap Junctions; In Vitro Techniques; Interneurons; Models, Neurological; Neocortex; Neural Inhibition; Patch-Clamp Techniques; Picrotoxin; Quinoxalines; Rats; Synapses; Synaptic Transmission; Time Factors; Valine | 2005 |
Differentiation of mouse embryonic stem cells into a defined neuronal lineage.
Topics: Animals; Bicuculline; Blotting, Western; Calmodulin-Binding Proteins; Carrier Proteins; Cell Count; Cell Differentiation; Cell Lineage; Cells, Cultured; Drug Interactions; Electric Stimulation; Embryo, Mammalian; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Eye Proteins; Fatty Acid-Binding Protein 7; Fatty Acid-Binding Proteins; GABA Antagonists; Glial Fibrillary Acidic Protein; Glutamic Acid; Homeodomain Proteins; Immunohistochemistry; Indoles; Intermediate Filament Proteins; Membrane Potentials; Mice; Nerve Tissue Proteins; Nestin; Neuroglia; Neurogranin; Neurons; Paired Box Transcription Factors; Patch-Clamp Techniques; PAX6 Transcription Factor; Quinoxalines; Receptor, Nerve Growth Factor; Receptor, trkA; Receptors, AMPA; Receptors, Nerve Growth Factor; Repressor Proteins; Stem Cells; Synaptophysin; Tetrodotoxin; Time Factors; Tretinoin; Tubulin; Valine | 2004 |
Fast endocytosis is inhibited by GABA-mediated chloride influx at a presynaptic terminal.
Topics: Animals; Bicuculline; Calcium; Cells, Cultured; Chelating Agents; Chlorides; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Endocytosis; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Goldfish; In Vitro Techniques; Ionophores; Membrane Potentials; Microscopy, Electron, Transmission; Models, Neurological; Neural Inhibition; Neurons; Nystatin; Patch-Clamp Techniques; Phosphinic Acids; Picrotoxin; Presynaptic Terminals; Pyridines; Quinoxalines; Retina; Time Factors; Valine | 2004 |
The linoleic acid derivative FR236924 facilitates hippocampal synaptic transmission by enhancing activity of presynaptic alpha7 acetylcholine receptors on the glutamatergic terminals.
Topics: Alkanes; Animals; Bicuculline; Bungarotoxins; Chromatography, High Pressure Liquid; Cyclopropanes; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Glutamic Acid; Hippocampus; In Vitro Techniques; Indoles; Linoleic Acid; Lysine; Male; Maleimides; Mecamylamine; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Patch-Clamp Techniques; Presynaptic Terminals; Protein Kinase C; Pyramidal Cells; Quinoxalines; Rats; Rats, Wistar; Receptors, Nicotinic; Receptors, Presynaptic; Synaptic Transmission; Valine | 2005 |
Functional cross-talk between fatty acid synthesis and nonribosomal peptide synthesis in quinoxaline antibiotic-producing streptomycetes.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Binding Sites; Carboxylic Acids; Chromatography, Thin Layer; Cloning, Molecular; DNA; Echinomycin; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Fatty Acid Synthases; Genome; Kinetics; Lactones; Models, Chemical; Molecular Sequence Data; Peptide Biosynthesis; Peptide Biosynthesis, Nucleic Acid-Independent; Peptides; Plasmids; Protein Binding; Protein Structure, Tertiary; Quinoxalines; Recombinant Proteins; Sequence Homology, Amino Acid; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Streptomyces; Streptomyces lividans; Substrate Specificity; Valine | 2005 |
Synaptic physiology in the cochlear nucleus angularis of the chick.
Topics: Age Factors; Animals; Bicuculline; Chick Embryo; Cochlear Nerve; Cochlear Nucleus; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Glycine Agents; Immunohistochemistry; In Vitro Techniques; Kinetics; Kv1.2 Potassium Channel; Neurons; Patch-Clamp Techniques; Potassium Channels, Voltage-Gated; Quinoxalines; Reaction Time; Strychnine; Synapses; Synaptic Transmission; Valine | 2005 |
Activity dependence of cortical axon branch formation: a morphological and electrophysiological study using organotypic slice cultures.
Topics: Action Potentials; Animals; Axons; Cerebral Cortex; Electroporation; Luminescent Proteins; Microelectrodes; Microscopy, Confocal; Neocortex; Neurons; Occipital Lobe; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Tetrodotoxin; Tissue Culture Techniques; Valine | 2005 |
Activity-dependent maturation of excitatory synaptic connections in solitary neuron cultures of mouse neocortex.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Cells, Cultured; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Mice; Mice, Inbred C57BL; Neocortex; Neurons; Pyridinium Compounds; Quaternary Ammonium Compounds; Quinoxalines; Statistics, Nonparametric; Synapses; Synaptic Transmission; Tetrodotoxin; Time Factors; Valine | 2005 |
Kv1 K+ channels control Purkinje cell output to facilitate postsynaptic rebound discharge in deep cerebellar neurons.
Topics: Action Potentials; Animals; Calcium Signaling; Cerebellum; Dendrites; Elapid Venoms; Electric Stimulation; Excitatory Postsynaptic Potentials; Ion Transport; Male; Neurotoxins; Patch-Clamp Techniques; Phosphinic Acids; Picrotoxin; Potassium; Potassium Channel Blockers; Potassium Channels; Propanolamines; Purkinje Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; Scorpion Venoms; Shaker Superfamily of Potassium Channels; Sodium; Tetrodotoxin; Valine | 2005 |
5-HT1B receptor-mediated presynaptic inhibition of GABA release in the suprachiasmatic nucleus.
Topics: Animals; Bicuculline; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Membrane Potentials; Mice; Mice, Knockout; Neural Inhibition; Neurons; Patch-Clamp Techniques; Presynaptic Terminals; Pyridines; Pyrroles; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1B; Serotonin Receptor Agonists; Suprachiasmatic Nucleus; Tetrodotoxin; Time Factors; Valine | 2005 |
Maturation of cultured hippocampal slices results in increased excitability in granule cells.
Topics: Animals; Animals, Newborn; Cellular Senescence; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Hippocampus; Lysine; Neural Networks, Computer; Neurons; Organ Culture Techniques; Patch-Clamp Techniques; Picrotoxin; Quinoxalines; Rats; Rats, Sprague-Dawley; Reaction Time; Time Factors; Valine | 2005 |
Learning twice is different from learning once and from learning more.
Topics: Animals; Avoidance Learning; Behavior, Animal; Benzylamines; Corpus Striatum; Dichlororibofuranosylbenzimidazole; Electroshock; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Extinction, Psychological; Hippocampus; Learning; Male; Maze Learning; Quinoxalines; Rats; Rats, Wistar; Reaction Time; Receptors, N-Methyl-D-Aspartate; Retention, Psychology; Statistics, Nonparametric; Sulfonamides; Time Factors; Valine | 2005 |
Long-term depression at olfactory nerve synapses.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Calcium; Diagnostic Imaging; Dopamine Antagonists; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; In Vitro Techniques; Long-Term Synaptic Depression; Methoxyhydroxyphenylglycol; Mice; Mice, Inbred ICR; N-Methylaspartate; Neurons; Olfactory Bulb; Patch-Clamp Techniques; Quinoxalines; Sodium Channel Blockers; Sulpiride; Synapses; Tetrodotoxin; Time Factors; Valine | 2005 |
The neurotrophin receptor p75NTR modulates long-term depression and regulates the expression of AMPA receptor subunits in the hippocampus.
Topics: Animals; Blotting, Western; Depression; Excitatory Postsynaptic Potentials; Gene Expression Regulation; Hippocampus; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutation; Neuronal Plasticity; Quinoxalines; Receptor, Nerve Growth Factor; Receptors, AMPA; Receptors, Nerve Growth Factor; Signal Transduction; Synaptic Transmission; Valine | 2005 |
Chronic intermittent ethanol exposure enhances NMDA-receptor-mediated synaptic responses and NMDA receptor expression in hippocampal CA1 region.
Topics: Animals; Blotting, Western; Body Weight; Brain; Central Nervous System Depressants; Dose-Response Relationship, Radiation; Drug Administration Schedule; Drug Interactions; Electric Stimulation; Ethanol; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Hippocampus; In Vitro Techniques; Male; Organ Size; Phosphinic Acids; Picrotoxin; Propanolamines; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Time Factors; Valine | 2005 |
Effects of emodin on synaptic transmission in rat hippocampal CA1 pyramidal neurons in vitro.
Topics: Adenosine; Adenosine Deaminase; Animals; Bicuculline; Dose-Response Relationship, Drug; Drug Interactions; Electrophysiology; Emodin; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Male; Neural Inhibition; Purinergic P1 Receptor Antagonists; Pyramidal Cells; Quinoxalines; Rats; Rats, Wistar; Synaptic Transmission; Theophylline; Valine | 2005 |
AMPA receptor stimulation increases alpha5beta1 integrin surface expression, adhesive function and signaling.
Topics: Alkaloids; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzophenanthridines; Biotinylation; Blotting, Western; Brain; Brefeldin A; Calcium Channel Blockers; Cell Adhesion; Cells, Cultured; Chlorocebus aethiops; Cytoskeletal Proteins; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Gene Expression Regulation; Glycine; In Vitro Techniques; Integrin alphaVbeta3; Mitogen-Activated Protein Kinase Kinases; Neurons; Nifedipine; Paxillin; Phenanthridines; Phosphoproteins; Protein Synthesis Inhibitors; Protein-Tyrosine Kinases; Quinoxalines; Rats; Receptors, AMPA; src-Family Kinases; Time Factors; Transfection; Valine | 2005 |
Selective sparing of hippocampal CA3 cells following in vitro ischemia is due to selective inhibition by acidosis.
Topics: Acidosis; Animals; Animals, Newborn; Calcium; Cell Death; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; Hydrogen-Ion Concentration; Ischemia; Mice; Neural Inhibition; Neurons; Organ Culture Techniques; Patch-Clamp Techniques; Quinoxalines; Time Factors; Valine | 2005 |
In vivo calcium imaging of circuit activity in cerebellar cortex.
Topics: Animals; Animals, Newborn; Brain Mapping; Calcium; Cerebellar Cortex; Dendrites; Diagnostic Imaging; Dose-Response Relationship, Radiation; Egtazic Acid; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; Nerve Net; Neurons; Poloxamer; Quinoxalines; Rats; Rats, Wistar; Valine | 2005 |
Nicotine-induced switch in the nicotinic cholinergic mechanisms of facilitation of long-term potentiation induction.
Topics: Acetylcholinesterase; Aconitine; Animals; Animals, Newborn; Antibodies, Monoclonal; Cholinergic Fibers; Denervation; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Immunohistochemistry; Immunotoxins; In Vitro Techniques; Long-Term Potentiation; N-Glycosyl Hydrolases; Neural Inhibition; Neurons; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Patch-Clamp Techniques; Phosphinic Acids; Picrotoxin; Propanolamines; Quinoxalines; Rats; Receptors, Nicotinic; Ribosome Inactivating Proteins, Type 1; Saporins; Valine | 2005 |
Depression of extra-cellular GABA and increase of NMDA-induced nitric oxide following acute intra-nuclear administration of alcohol in the cerebellar nuclei of the rat.
Topics: Animals; Central Nervous System Depressants; Cerebellar Nuclei; Enzyme Inhibitors; Ethanol; Excitatory Amino Acid Antagonists; Extracellular Fluid; GABA Agonists; gamma-Aminobutyric Acid; Indazoles; Injections, Intraventricular; Male; Microdialysis; N-Methylaspartate; Nipecotic Acids; Nitric Oxide; Quinoxalines; Rats; Rats, Wistar; Tiagabine; Valine | 2005 |
Developmental changes in NMDA neurotoxicity reflect developmental changes in subunit composition of NMDA receptors.
Topics: Age Factors; Animals; Biomarkers; Calpain; Dipeptides; Disks Large Homolog 4 Protein; Dizocilpine Maleate; Enzyme Activation; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Gene Expression Regulation, Developmental; Glucose; Hippocampus; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; L-Lactate Dehydrogenase; Membrane Proteins; N-Methylaspartate; Neurons; Oxygen; Phenols; Piperidines; Propidium; Protein Subunits; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spectrin; Valine | 2006 |
Zinc modulates bidirectional hippocampal plasticity by effects on NMDA receptors.
Topics: Animals; Chelating Agents; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; Long-Term Potentiation; Long-Term Synaptic Depression; Neuronal Plasticity; Organ Culture Techniques; Phenanthrolines; Piperidines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Valine; Zinc | 2006 |
Alteration in sensitivity of ionotropic glutamate receptors and tachykinin receptors in spinal cord contribute to development and maintenance of nerve injury-evoked neuropathic pain.
Topics: Alanine; Analgesics; Animals; Behavior, Animal; Benzamides; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Indoles; Isoindoles; Male; N-Methylaspartate; Pain; Pain Measurement; Piperidines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Tachykinin; Sciatic Nerve; Spinal Cord; Substance P; Valine | 2006 |
Modulation of isolated N-methyl-d-aspartate receptor response under hyperbaric conditions.
Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Helium; High Pressure Neurological Syndrome; Hippocampus; In Vitro Techniques; Magnesium; Male; Pressure; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Valine | 2006 |
Effects of intrastriatal injections of glutamate receptor antagonists on the severity of paroxysmal dystonia in the dtsz mutant.
Topics: Animals; Basal Ganglia; Caudate Nucleus; Cricetinae; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Dystonia; Excitatory Amino Acid Antagonists; Microinjections; Movement; Muscle Contraction; Mutation; Posture; Putamen; Pyrrolidinones; Quinoxalines; Reaction Time; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Severity of Illness Index; Valine | 2007 |
GABA actions in hippocampal area CA3 during postnatal development: differential shift from depolarizing to hyperpolarizing in somatic and dendritic compartments.
Topics: Age Factors; Animals; Animals, Newborn; Dendrites; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Membrane Potentials; Muscimol; Neural Inhibition; Neurons; Patch-Clamp Techniques; Pyridazines; Quinoxalines; Rats; Rats, Wistar; Valine | 2008 |
Effects of in situ administration of excitatory amino acid antagonists on rapid microglial and astroglial reactions in rat hippocampus following traumatic brain injury.
Topics: Animals; Astrocytes; Brain Injuries; CD11b Antigen; Disease Models, Animal; Excitatory Amino Acid Antagonists; Glial Fibrillary Acidic Protein; Gliosis; Hippocampus; Ion Channels; Kynurenic Acid; Male; Microglia; Quinoxalines; Rats; Rats, Wistar; Receptors, Glutamate; Sodium Channel Blockers; Time Factors; Treatment Outcome; Up-Regulation; Valine | 2008 |
Modulation of spontaneous hippocampal synaptic events with 5-hydroxyindole, 4OH-GTS-21, and rAAV-mediated alpha7 nicotinic receptor gene transfer.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Anabasine; Animals; Animals, Newborn; Dependovirus; Drug Interactions; Excitatory Amino Acid Antagonists; Gene Transfer Techniques; Hippocampus; In Vitro Techniques; Indoles; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Sodium Channel Blockers; Synapses; Synaptic Transmission; Tetrodotoxin; Valine | 2008 |
Rapid synaptic scaling induced by changes in postsynaptic firing.
Topics: Anesthetics, Local; Animals; Animals, Newborn; Bacterial Proteins; Brain; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Excitatory Amino Acid Antagonists; Hydrogen-Ion Concentration; Luminescent Proteins; Neurons; Nickel; Quinoxalines; Rats; Rats, Long-Evans; Receptors, AMPA; Synapses; Synaptic Transmission; Tetrodotoxin; Time Factors; Transfection; Valine | 2008 |
Glutamatergic contributions to nicotinic acetylcholine receptor agonist-evoked cholinergic transients in the prefrontal cortex.
Topics: Acetylcholine; Analysis of Variance; Animals; Choline; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Electrochemistry; Evoked Potentials; Excitatory Amino Acid Antagonists; Glutamic Acid; In Vitro Techniques; Male; Mecamylamine; Neostigmine; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Prefrontal Cortex; Pyridines; Pyrrolidines; Quinoxalines; Rats; Sodium Channel Blockers; Tetrodotoxin; Valine | 2008 |
Excitatory GABA in rodent developing neocortex in vitro.
Topics: Age Factors; Animals; Animals, Newborn; Bumetanide; Excitatory Amino Acid Antagonists; Female; GABA Agents; gamma-Aminobutyric Acid; In Vitro Techniques; Interneurons; Lysine; Male; Membrane Potentials; Mice; Models, Neurological; Neocortex; Patch-Clamp Techniques; Pyramidal Cells; Quinoxalines; Sodium Potassium Chloride Symporter Inhibitors; Valine | 2008 |
DNA binding by analogues of the bifunctional intercalator TANDEM.
Topics: Binding Sites; Deoxyribonuclease I; DNA; DNA Footprinting; Intercalating Agents; Lysine; Models, Molecular; Naphthalenes; Quinoxalines; Valine | 2008 |
Localization and function of NK(3) subtype tachykinin receptors of layer V pyramidal neurons of the guinea-pig medial prefrontal cortex.
Topics: Animals; Autoradiography; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Guinea Pigs; In Vitro Techniques; Iodine Isotopes; Male; Membrane Potentials; Neurokinin B; Patch-Clamp Techniques; Peptide Fragments; Prefrontal Cortex; Protein Binding; Pyramidal Cells; Quinolines; Quinoxalines; Receptors, Neurokinin-3; Substance P; Valine | 2008 |
Continuous shifts in the active set of spinal interneurons during changes in locomotor speed.
Topics: Action Potentials; Adaptation, Physiological; Animals; Behavior, Animal; Dose-Response Relationship, Radiation; Electric Stimulation; Electronic Data Processing; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Interneurons; Larva; Motor Neurons; Movement; Nerve Net; Neural Inhibition; Patch-Clamp Techniques; Periodicity; Quinoxalines; Recruitment, Neurophysiological; Spinal Cord; Swimming; Synaptic Potentials; Valine; Zebrafish | 2008 |
Abnormal network activity in a targeted genetic model of human double cortex.
Topics: Analysis of Variance; Animals; Animals, Genetically Modified; Animals, Newborn; Bicuculline; Cerebral Cortex; Disease Models, Animal; Doublecortin Domain Proteins; Doublecortin Protein; Electroporation; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Green Fluorescent Proteins; Humans; In Vitro Techniques; Malformations of Cortical Development; Membrane Potentials; Microtubule-Associated Proteins; Mutation; Nerve Net; Neurons; Neuropeptides; Pregnancy; Quinoxalines; Rats; Rats, Wistar; RNA, Small Interfering; Sodium Channel Blockers; Tetrodotoxin; Valine | 2009 |
Glucocorticoids regulate glutamate and GABA synapse-specific retrograde transmission via divergent nongenomic signaling pathways.
Topics: Animals; Arginine; Cannabinoid Receptor Modulators; Cyclic AMP-Dependent Protein Kinases; Dexamethasone; Dronabinol; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glucocorticoids; Glutamic Acid; GTP-Binding Proteins; Guanosine Diphosphate; Hypothalamus; In Vitro Techniques; Male; Neurons; Nitric Oxide; Nitric Oxide Donors; Patch-Clamp Techniques; Penicillamine; Piperidines; Pyrans; Pyrazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; Rimonabant; Signal Transduction; Synapses; Synaptic Transmission; Thionucleotides; Valine | 2009 |
Homeostatic presynaptic suppression of neuronal network bursts.
Topics: Action Potentials; Anesthetics, Local; Animals; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Electric Stimulation; Embryo, Mammalian; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Fluid; Green Fluorescent Proteins; Hippocampus; Inhibitory Postsynaptic Potentials; Lidocaine; N-Methylaspartate; Nerve Net; Neurons; Presynaptic Terminals; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptosomal-Associated Protein 25; Tetrodotoxin; Time Factors; Transfection; Valine; Vesicle-Associated Membrane Protein 2 | 2009 |
Synchronous GABA-receptor-dependent potentials in limbic areas of the in-vitro isolated adult guinea pig brain.
Topics: 4-Aminopyridine; Animals; Bicuculline; Cortical Spreading Depression; Cortical Synchronization; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; Guinea Pigs; Inhibitory Postsynaptic Potentials; Limbic System; Neurons; Olfactory Pathways; Organ Culture Techniques; Potassium Channel Blockers; Quinoxalines; Receptors, GABA; Valine | 2009 |
Depolarizing GABAergic synaptic input triggers endocannabinoid-mediated retrograde synaptic signaling.
Topics: Aniline Compounds; Animals; Animals, Newborn; Arachidonic Acids; Benzamides; Bicuculline; Biophysics; Calcium; Calcium Signaling; Cannabinoid Receptor Antagonists; Cannabinoid Receptor Modulators; Carbamates; Cerebellum; Electric Stimulation; Endocannabinoids; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Fluoresceins; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glycerides; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Lactones; Mice; Muscimol; Orlistat; Patch-Clamp Techniques; Piperidines; Purkinje Cells; Pyrazoles; Quinoxalines; Rimonabant; Signal Transduction; Synapses; Valine | 2009 |
KCC2 expression promotes the termination of cortical interneuron migration in a voltage-sensitive calcium-dependent manner.
Topics: Age Factors; Animals; Animals, Newborn; Bicuculline; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Movement; Cerebral Cortex; Electroporation; Embryo, Mammalian; Female; GABA Agents; gamma-Aminobutyric Acid; Gene Expression Regulation; Glutamic Acid; Green Fluorescent Proteins; Homeodomain Proteins; Interneurons; K Cl- Cotransporters; LIM-Homeodomain Proteins; Membrane Potentials; Mice; Mice, Inbred BALB C; Mice, Transgenic; Microtubule-Associated Proteins; Models, Biological; Muscimol; Nerve Tissue Proteins; Nifedipine; omega-Conotoxin GVIA; Organ Culture Techniques; Pregnancy; Quinoxalines; Receptors, N-Methyl-D-Aspartate; RNA, Small Interfering; Sequence Deletion; Symporters; Transcription Factors; Valine | 2009 |
Synaptic and extrasynaptic factors governing glutamatergic retinal waves.
Topics: Amino Acid Transport Systems, Acidic; Animals; Animals, Newborn; Aspartic Acid; Calcium; Dihydro-beta-Erythroidine; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; Glutamic Acid; In Vitro Techniques; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Biological; N-Methylaspartate; Neural Inhibition; Nicotinic Antagonists; Patch-Clamp Techniques; Pyridazines; Quinoxalines; Retinal Ganglion Cells; Synapses; Synaptic Transmission; Time Factors; Valine; Vesicular Glutamate Transport Protein 1 | 2009 |
Estradiol negative feedback regulation by glutamatergic afferents to A15 dopaminergic neurons: variation with season.
Topics: Animals; Estradiol; Excitatory Amino Acid Antagonists; Feedback, Physiological; Female; Luteinizing Hormone; Neurons, Afferent; Quinoxalines; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Seasons; Sheep; Tyrosine 3-Monooxygenase; Valine; Vesicular Glutamate Transport Protein 2; Vesicular Inhibitory Amino Acid Transport Proteins | 2009 |
Long-term potentiation in the rat medial vestibular nuclei depends on locally synthesized 17beta-estradiol.
Topics: Animals; Animals, Newborn; Aromatase Inhibitors; Bicuculline; Biophysics; Drug Interactions; Electric Stimulation; Estradiol; Estrogen Antagonists; Excitatory Amino Acid Antagonists; Fulvestrant; GABA Antagonists; In Vitro Techniques; Letrozole; Long-Term Potentiation; Male; Nitriles; Quinoxalines; Rats; Rats, Wistar; Triazoles; Valine; Vestibular Nuclei | 2009 |
GABA(B) receptor activation triggers BDNF release and promotes the maturation of GABAergic synapses.
Topics: Animals; Animals, Newborn; Brain-Derived Neurotrophic Factor; Cells, Cultured; CREB-Binding Protein; Enzyme-Linked Immunosorbent Assay; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; gamma-Aminobutyric Acid; Green Fluorescent Proteins; Hippocampus; Lysine; Membrane Potentials; Mice; Mice, Knockout; Neurons; Patch-Clamp Techniques; Phosphinic Acids; Propanolamines; Quinoxalines; Receptors, GABA-B; Sodium Channel Blockers; Synapses; Tetrodotoxin; Valine | 2009 |
Increased basal synaptic inhibition of hippocampal area CA1 pyramidal neurons by an antiepileptic drug that enhances I(H).
Topics: 4-Aminopyridine; Action Potentials; Animals; Animals, Newborn; Anticonvulsants; Biophysics; CA1 Region, Hippocampal; Cadmium Chloride; Calcium Channel Blockers; Electric Stimulation; Excitatory Amino Acid Antagonists; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Interneurons; Lamotrigine; Lysine; Male; Neural Inhibition; Patch-Clamp Techniques; Potassium Channel Blockers; Pyramidal Cells; Quinoxalines; Rats; Rats, Long-Evans; Tetraethylammonium; Triazines; Valine | 2010 |
Evidence against AMPA receptor-lacking glutamatergic synapses in the superficial dorsal horn of the rat spinal cord.
Topics: Age Factors; Animals; Animals, Newborn; Biophysics; Chelating Agents; Disks Large Homolog 4 Protein; Egtazic Acid; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins; Patch-Clamp Techniques; Posterior Horn Cells; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Spinal Cord; Synapses; Valine | 2009 |
Diacylglycerol lipase is not involved in depolarization-induced suppression of inhibition at unitary inhibitory connections in mouse hippocampus.
Topics: Animals; Animals, Newborn; Benzoxazines; Cyclohexanones; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; GABA Antagonists; Green Fluorescent Proteins; Hippocampus; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Lipoprotein Lipase; Lysine; Mice; Mice, Inbred C57BL; Mice, Knockout; Morpholines; Naphthalenes; Neocortex; Neural Inhibition; Neurons; Pyridazines; Quinoxalines; Receptor, Cannabinoid, CB1; Valine | 2010 |
Effects of pharmacological entopeduncular manipulations on idiopathic dystonia in the dt(sz) mutant hamster.
Topics: Animals; Animals, Newborn; Cricetinae; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Dystonia; Entopeduncular Nucleus; Excitatory Amino Acid Antagonists; GABA Agents; Microinjections; Muscimol; Nipecotic Acids; Oximes; Pentylenetetrazole; Quinoxalines; Reaction Time; Severity of Illness Index; Time Factors; Valine | 2010 |
NMDA receptor antagonism in the basolateral but not central amygdala blocks the extinction of Pavlovian fear conditioning in rats.
Topics: Acoustic Stimulation; Amygdala; Animals; Auditory Perception; Conditioning, Classical; Excitatory Amino Acid Antagonists; Extinction, Psychological; Fear; Freezing Reaction, Cataleptic; Male; Memory; Quinoxalines; Rats; Rats, Long-Evans; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Valine | 2010 |
Adrenergic receptor-mediated disinhibition of mitral cells triggers long-term enhancement of synchronized oscillations in the olfactory bulb.
Topics: Action Potentials; Adrenergic alpha-Agonists; Animals; Animals, Newborn; Bicuculline; Biological Clocks; Biophysical Phenomena; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; GABA-A Receptor Antagonists; In Vitro Techniques; Inhibitory Postsynaptic Potentials; N-Methylaspartate; Neurons; Norepinephrine; Olfactory Bulb; Pyridazines; Quinoxalines; Rats; Receptors, Adrenergic; Valine | 2010 |
Metaplasticity at single glutamatergic synapses.
Topics: Anesthetics, Local; Animals; Biophysics; Dendritic Spines; Electric Stimulation; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Green Fluorescent Proteins; Hippocampus; Long-Term Potentiation; Models, Biological; Neuronal Plasticity; Neurons; Patch-Clamp Techniques; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Synapses; Tetanus Toxin; Tetrodotoxin; Time Factors; Transfection; Valine | 2010 |
Encoding of the cough reflex in anesthetized guinea pigs.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Anesthesia; Animals; Biphenyl Compounds; Citric Acid; Cough; Dose-Response Relationship, Drug; Electric Stimulation; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Guinea Pigs; Male; Mechanoreceptors; Propionates; Quinoxalines; Receptors, GABA; Receptors, N-Methyl-D-Aspartate; Recurrent Laryngeal Nerve; Reflex; Respiratory Mucosa; Sensory Receptor Cells; Solitary Nucleus; Substance P; Trachea; Vagus Nerve; Valine | 2011 |
Short-term adaptation of conditioned fear responses through endocannabinoid signaling in the central amygdala.
Topics: Action Potentials; Adaptation, Psychological; Amygdala; Animals; Behavior, Animal; Cannabinoid Receptor Modulators; Conditioning, Psychological; Electric Stimulation; Endocannabinoids; Excitatory Amino Acid Antagonists; Extinction, Psychological; Fear; GABA Antagonists; Gene Expression Regulation; In Vitro Techniques; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Knockout; Phosphinic Acids; Piperidines; Propanolamines; Pyrazoles; Pyridazines; Quinoxalines; Receptor, Cannabinoid, CB1; Sensory Receptor Cells; Signal Transduction; Time Factors; Valine | 2011 |
Information capacity and transmission are maximized in balanced cortical networks with neuronal avalanches.
Topics: Analysis of Variance; Animals; Animals, Newborn; Cerebral Cortex; Computer Simulation; Dose-Response Relationship, Drug; Entropy; Evoked Potentials; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; Likelihood Functions; Macaca mulatta; Male; Microelectrodes; Models, Neurological; Nerve Net; Neurons; Organ Culture Techniques; Picrotoxin; Quinoxalines; Rats; Synaptic Transmission; Valine | 2011 |
Parasagittally aligned, mGluR1-dependent patches are evoked at long latencies by parallel fiber stimulation in the mouse cerebellar cortex in vivo.
Topics: Animals; Benzoates; Calcium; Cerebellar Cortex; Electric Stimulation; Estrenes; Evoked Potentials; Glycine; Long-Term Potentiation; Male; Mice; Mice, Inbred Strains; Models, Animal; Nerve Fibers; Purkinje Cells; Pyrrolidinones; Quinoxalines; Receptors, AMPA; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Ryanodine; Valine | 2011 |
Glutamatergic pre-ictal discharges emerge at the transition to seizure in human epilepsy.
Topics: Action Potentials; Adolescent; Adult; Analysis of Variance; Biophysics; Brain Mapping; Confidence Intervals; Electric Stimulation; Electroencephalography; Epilepsy, Temporal Lobe; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Hippocampus; Humans; In Vitro Techniques; Magnesium; Male; Middle Aged; Nerve Net; Potassium Chloride; Quinoxalines; Valine; Young Adult | 2011 |
Excitation-inhibition balance in the CA3 network--neuronal specificity and activity-dependent plasticity.
Topics: Animals; CA3 Region, Hippocampal; Convulsants; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Antagonists; Kindling, Neurologic; Male; Nerve Net; Neuronal Plasticity; Neurons; Pentylenetetrazole; Quinoxalines; Rats; Rats, Wistar; Seizures; Synaptic Transmission; Valine | 2011 |
GABA(B) restrains release from singly-evoked GABA terminals.
Topics: Analysis of Variance; Animals; Benzylamines; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Male; Neurons; Phosphinic Acids; Pyridazines; Quinoxalines; Rats; Rats, Sprague-Dawley; Reaction Time; Sodium Channel Blockers; Solitary Nucleus; Synapses; Tetrodotoxin; Valine | 2011 |
A circadian clock in hippocampus is regulated by interaction between oligophrenin-1 and Rev-erbα.
Topics: Analysis of Variance; Animals; ARNTL Transcription Factors; Bicuculline; Cells, Cultured; Cerebral Cortex; Chlorocebus aethiops; Circadian Clocks; Cysteine Proteinase Inhibitors; Cytoskeletal Proteins; Dendrites; Drug Interactions; Embryo, Mammalian; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; Gene Expression Regulation; Green Fluorescent Proteins; GTPase-Activating Proteins; Hippocampus; Humans; Immunoprecipitation; Leupeptins; Mice; Mice, Knockout; Mutation; Neurons; Nuclear Proteins; Nuclear Receptor Subfamily 1, Group D, Member 1; Quinoxalines; Rats; RNA, Messenger; RNA, Small Interfering; Sodium Channel Blockers; Tetrodotoxin; Time Factors; Transfection; Two-Hybrid System Techniques; Valine | 2011 |
Ivy/neurogliaform interneurons coordinate activity in the neurogenic niche.
Topics: Action Potentials; Animals; Animals, Newborn; Bacterial Proteins; Biophysical Phenomena; Cell Adhesion Molecules, Neuronal; Electric Stimulation; Excitatory Amino Acid Antagonists; Extracellular Matrix Proteins; GABA Antagonists; Glutamic Acid; Green Fluorescent Proteins; Interneurons; Iontophoresis; Luminescent Proteins; Lysine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Models, Neurological; Nerve Net; Nerve Tissue Proteins; Neural Inhibition; Neurogenesis; Neuropeptide Y; Nitric Oxide Synthase Type I; Patch-Clamp Techniques; Picrotoxin; Pro-Opiomelanocortin; Quinoxalines; Reelin Protein; Serine Endopeptidases; Stem Cell Niche; Synaptic Potentials; Time Factors; Valine | 2011 |
State-dependent, bidirectional modulation of neural network activity by endocannabinoids.
Topics: 4-Aminopyridine; Action Potentials; Animals; Animals, Newborn; Benzothiadiazines; Brain; Cannabinoid Receptor Modulators; Cells, Cultured; Electric Stimulation; Endocannabinoids; Excitatory Amino Acid Antagonists; GABA Antagonists; In Vitro Techniques; Mice; Mice, Transgenic; Nerve Net; Neural Inhibition; Neurons; Organophosphorus Compounds; Picrotoxin; Piperidines; Potassium Channel Blockers; Pyrazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Sodium Channel Blockers; Tetrodotoxin; Valine | 2011 |
Influence of sex and estrous cycle on synaptic responses of the medial vestibular nuclei in rats: role of circulating 17β-estradiol.
Topics: Analysis of Variance; Androgens; Animals; Electric Stimulation; Estradiol; Estrogens; Estrous Cycle; Evoked Potentials; Excitatory Amino Acid Antagonists; Female; In Vitro Techniques; Long-Term Potentiation; Male; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Wistar; Sex Characteristics; Synapses; Testosterone; Valine; Vestibular Nuclei | 2012 |
Sphingomyelinase selectively reduces M1 muscarinic receptors in rat hippocampal membranes.
Topics: Animals; Arrestins; beta-Arrestins; Bicuculline; Biotinylation; Cell Membrane; Drug Interactions; Excitatory Amino Acid Antagonists; G-Protein-Coupled Receptor Kinase 2; GABA-A Receptor Antagonists; Gene Expression Regulation; Hippocampus; Immunoprecipitation; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Male; Muscarinic Agonists; Patch-Clamp Techniques; Pilocarpine; Pyramidal Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M1; Sphingomyelin Phosphodiesterase; Time Factors; Valine | 2012 |
MPTP modulates hippocampal synaptic transmission and activity-dependent synaptic plasticity via dopamine receptors.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzazepines; Biophysics; Dopamine Antagonists; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; Mice; Mice, Inbred C57BL; Neural Pathways; Neuronal Plasticity; Neurons; Neurotoxins; Patch-Clamp Techniques; Quinoxalines; Receptors, Dopamine; Sodium Channel Blockers; Sulpiride; Tetrodotoxin; Time Factors; Valine | 2012 |
Transgenic quail as a model for research in the avian nervous system: a comparative study of the auditory brainstem.
Topics: Animals; Animals, Genetically Modified; Animals, Newborn; Brain Stem; Chick Embryo; Cochlea; Coturnix; Electric Stimulation; Embryo, Nonmammalian; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Fluoxetine; Functional Laterality; GABA Antagonists; Gene Expression Regulation, Developmental; Glutamate Decarboxylase; Green Fluorescent Proteins; Humans; In Vitro Techniques; Kv1.3 Potassium Channel; Lentivirus; Male; Membrane Potentials; Microtubule-Associated Proteins; Models, Animal; Neural Pathways; Neurons; Okadaic Acid; Patch-Clamp Techniques; Picrotoxin; Pyrans; Quinoxalines; Selective Serotonin Reuptake Inhibitors; Synapsins; Transgenes; Valine | 2013 |
Enhanced NMDA receptor-dependent thalamic excitation and network oscillations in stargazer mice.
Topics: Action Potentials; Animals; Biophysical Phenomena; Calcium Channels; Disease Models, Animal; Electric Stimulation; Epilepsy, Absence; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Gene Expression Regulation; Glutamates; In Vitro Techniques; Indoles; Male; Mice; Mice, Mutant Strains; Nerve Net; Neurons; Patch-Clamp Techniques; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Statistics, Nonparametric; Synapses; Thalamic Nuclei; Time Factors; Valine; Vesicular Glutamate Transport Protein 1 | 2012 |
Astrocyte-derived thrombospondins mediate the development of hippocampal presynaptic plasticity in vitro.
Topics: Adenosine; Amines; Animals; Animals, Newborn; Astrocytes; Biophysics; Coculture Techniques; CREB-Binding Protein; Culture Media, Conditioned; Cyclic AMP; Cyclohexanecarboxylic Acids; Dynamin I; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; Male; N-Methylaspartate; Nerve Tissue Proteins; Neuronal Plasticity; Organ Culture Techniques; Patch-Clamp Techniques; Phosphorylation; Potassium Chloride; Presynaptic Terminals; Protein Kinase Inhibitors; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Statistics, Nonparametric; Synapses; Thionucleotides; Thrombospondins; Valine; Vesicular Glutamate Transport Protein 1 | 2012 |
Optogenetic analysis of neuronal excitability during global ischemia reveals selective deficits in sensory processing following reperfusion in mouse cortex.
Topics: Anesthetics, Local; Animals; Bacterial Proteins; Carrier Proteins; Channelrhodopsins; Disease Models, Animal; Electroencephalography; Evoked Potentials; Excitatory Amino Acid Antagonists; Forelimb; Hyperalgesia; In Vitro Techniques; Ischemia; Luminescent Proteins; Membrane Potentials; Mice; Mice, Transgenic; Neurons; Optogenetics; Physical Stimulation; Quinoxalines; Reperfusion Injury; Tetrodotoxin; Valine | 2012 |
Relationship between increase in astrocytic GLT-1 glutamate transport and late-LTP.
Topics: Alanine Transaminase; Analysis of Variance; Animals; Animals, Newborn; Aspartic Acid; Astrocytes; Biophysics; Biotinylation; Cells, Cultured; Colforsin; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Excitatory Postsynaptic Potentials; Flow Cytometry; Glial Fibrillary Acidic Protein; Glutamates; Glutamic Acid; Glycine; Hippocampus; In Vitro Techniques; Indoles; Kainic Acid; Long-Term Potentiation; Male; Neurons; Protein Transport; Quinoxalines; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Tetrodotoxin; Valine | 2012 |
Involvement of NMDA receptors in nicotine-mediated central control of hypotensive effects.
Topics: Animals; Blood Pressure; Bradycardia; Dizocilpine Maleate; Drug Interactions; Excitatory Amino Acid Antagonists; Glutamic Acid; Heart Rate; Hypotension; Male; Nicotine; Nicotinic Agonists; Quinoxalines; Rats; Rats, Inbred WKY; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Solitary Nucleus; Valine | 2012 |
Physiologic brain activity causes DNA double-strand breaks in neurons, with exacerbation by amyloid-β.
Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Animals, Newborn; Cells, Cultured; Cerebral Cortex; Channelrhodopsins; Corpus Striatum; Corticosterone; Disease Models, Animal; DNA Breaks, Double-Stranded; Excitatory Amino Acid Antagonists; Exploratory Behavior; Gene Expression Regulation; Hippocampus; Histones; Humans; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurons; Photic Stimulation; Quinoxalines; Reactive Oxygen Species; Stress, Physiological; tau Proteins; Valine | 2013 |
Novel GABAergic circuits mediating excitation/inhibition of Cajal-Retzius cells in the developing hippocampus.
Topics: Age Factors; Animals; Animals, Newborn; Biophysics; Channelrhodopsins; Electric Stimulation; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; gamma-Aminobutyric Acid; Green Fluorescent Proteins; Hippocampus; In Vitro Techniques; Interneurons; Light; Male; Membrane Potentials; Methoxyhydroxyphenylglycol; Mice; Mice, Transgenic; Mutation; Nerve Net; Neural Inhibition; Optogenetics; Patch-Clamp Techniques; Proteins; Pyridazines; Quinoxalines; Receptors, CXCR4; RNA, Untranslated; Sodium Channel Blockers; Somatostatin; Synaptic Potentials; Tetrodotoxin; Valine | 2013 |
Exposure to cocaine regulates inhibitory synaptic transmission in the nucleus accumbens.
Topics: Anesthetics, Local; Animals; Cocaine; Conditioning, Operant; Electric Stimulation; Excitatory Amino Acid Antagonists; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Male; Neurons; Nucleus Accumbens; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Sprague-Dawley; Self Administration; Synapses; Tetrodotoxin; Time Factors; Valine | 2013 |
Hypothalamic neurotensin projections promote reward by enhancing glutamate transmission in the VTA.
Topics: Animals; Bacterial Proteins; Channelrhodopsins; Conditioning, Operant; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Hypothalamus; In Vitro Techniques; Light; Luminescent Proteins; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutation; Neural Pathways; Neurotensin; Pyrazoles; Quinolines; Quinoxalines; Receptors, Neurotensin; Reward; Self Stimulation; Signal Transduction; Tyrosine 3-Monooxygenase; Valine; Ventral Tegmental Area | 2013 |
Transmission of the respiratory rhythm to trigeminal and hypoglossal motor neurons in the American Bullfrog (Lithobates catesbeiana).
Topics: Action Potentials; Animals; Brain Stem; Choline O-Acetyltransferase; Excitatory Amino Acid Antagonists; Fluoresceins; Hypoglossal Nerve; In Vitro Techniques; Magnesium; Motor Neurons; Physical Stimulation; Quinoxalines; Rana catesbeiana; Respiratory Mechanics; Trigeminal Nerve; Valine | 2013 |
Persistent sodium current drives conditional pacemaking in CA1 pyramidal neurons under muscarinic stimulation.
Topics: Acetylcholine; Action Potentials; Animals; Animals, Newborn; Biological Clocks; CA1 Region, Hippocampal; Cholinergic Agents; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; In Vitro Techniques; Male; Mice; Muscarine; Nickel; Patch-Clamp Techniques; Phosphinic Acids; Picrotoxin; Propanolamines; Pyramidal Cells; Pyrimidines; Quinoxalines; Sodium Channel Blockers; Sodium Channels; Valine | 2013 |
Matrix metalloprotease activity shapes the magnitude of EPSPs and spike plasticity within the hippocampal CA3 network.
Topics: Action Potentials; Analysis of Variance; Animals; Biophysics; CA3 Region, Hippocampal; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; In Vitro Techniques; Matrix Metalloproteinases; Neuronal Plasticity; Picrotoxin; Quinoxalines; Rats; Rats, Wistar; Synapses; Valine | 2014 |
Copper chelation and exogenous copper affect circadian clock phase resetting in the suprachiasmatic nucleus in vitro.
Topics: Animals; Carbazoles; Chelating Agents; Circadian Clocks; Copper; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glutamic Acid; In Vitro Techniques; Indole Alkaloids; Male; Mice; Mice, Inbred C57BL; Molybdenum; Phenanthrolines; Quinoxalines; Suprachiasmatic Nucleus; Valine | 2014 |
Developmental molecular and functional cerebellar alterations induced by PCP4/PEP19 overexpression: implications for Down syndrome.
Topics: Animals; Animals, Newborn; Cerebellum; Excitatory Amino Acid Antagonists; Gene Expression Regulation, Developmental; Humans; In Vitro Techniques; Long-Term Synaptic Depression; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Nerve Tissue Proteins; Neurons; Psychomotor Performance; Quinoxalines; Reaction Time; Recognition, Psychology; Sodium Channel Blockers; Tetrodotoxin; Valine | 2014 |
Differential conduction velocity regulation in ipsilateral and contralateral collaterals innervating brainstem coincidence detector neurons.
Topics: Animals; Axons; Brain Stem; Chick Embryo; Electric Stimulation; Excitatory Amino Acid Antagonists; Female; Functional Laterality; GABA Antagonists; Imaging, Three-Dimensional; In Vitro Techniques; Male; Models, Neurological; Neural Conduction; Neural Pathways; Neurons; Patch-Clamp Techniques; Picrotoxin; Quinoxalines; Valine | 2014 |
Optogenetic assessment of horizontal interactions in primary visual cortex.
Topics: Action Potentials; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Excitatory Amino Acid Antagonists; Female; Luminescent Proteins; Male; Microscopy, Confocal; Neurons; Optogenetics; Orientation; Photic Stimulation; Quinoxalines; Rhodopsin; Synapsins; Tupaiidae; Valine; Visual Cortex; Visual Pathways | 2014 |
The discovery of potent nonstructural protein 5A (NS5A) inhibitors with a unique resistance profile-Part 1.
Topics: Animals; Antiviral Agents; Cell Line; Dogs; Drug Evaluation, Preclinical; Drug Resistance, Viral; Half-Life; Hepacivirus; Humans; Microsomes, Liver; Protease Inhibitors; Quinoxalines; Rats; Structure-Activity Relationship; Valine; Viral Nonstructural Proteins | 2014 |
Permeability analysis of neuroactive drugs through a dynamic microfluidic in vitro blood-brain barrier model.
Topics: Amines; Animals; Benzazepines; Biological Transport; Blood-Brain Barrier; Cell Survival; Cells, Cultured; Coculture Techniques; Cyclohexanecarboxylic Acids; Endothelial Cells; Ethosuximide; Gabapentin; gamma-Aminobutyric Acid; Indoles; L-Lactate Dehydrogenase; Mice; Microfluidic Analytical Techniques; Neuroglia; Permeability; Piperidines; Pyrroles; Quinoxalines; Rats; Rats, Sprague-Dawley; Sertraline; Sunitinib; Tetrahydronaphthalenes; Valine; Varenicline | 2014 |
Role of striatal NMDA receptor subunits in a model of paroxysmal dystonia.
Topics: Animals; Animals, Newborn; Carrier Proteins; Corpus Striatum; Cricetinae; Cytoskeletal Proteins; Disease Models, Animal; Dose-Response Relationship, Drug; Dystonia; Dystonin; Excitatory Amino Acid Antagonists; Female; Long-Term Potentiation; Magnesium; Male; Mutation; Nerve Tissue Proteins; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Severity of Illness Index; Time Factors; Valine | 2014 |
Sex Differences Distinguish Intracortical Glutamate Receptor-Mediated Regulation of Extracellular Dopamine Levels in the Prefrontal Cortex of Adult Rats.
Topics: Analysis of Variance; Animals; Benzylamines; Bicuculline; Chromatography, High Pressure Liquid; Dialysis; Dopamine; Estrous Cycle; Excitatory Amino Acid Agents; Extracellular Fluid; Female; GABA Agents; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Male; Phosphinic Acids; Prefrontal Cortex; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Sex Differentiation; Sodium Channel Blockers; Tetrodotoxin; Time Factors; Valine | 2016 |
Distinct representation and distribution of visual information by specific cell types in mouse superficial superior colliculus.
Topics: Action Potentials; Animals; Channelrhodopsins; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; Glutamate Decarboxylase; Green Fluorescent Proteins; Luminescent Proteins; Male; Mice; Mice, Transgenic; Neurons; Pyridazines; Quinoxalines; Receptors, Neurotensin; Superior Colliculi; Valine; Vesicular Inhibitory Amino Acid Transport Proteins; Visual Fields; Visual Pathways | 2014 |
Pro-brain-derived neurotrophic factor inhibits GABAergic neurotransmission by activating endocytosis and repression of GABAA receptors.
Topics: Animals; Animals, Newborn; Brain-Derived Neurotrophic Factor; Endocytosis; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Gene Expression Regulation; Hippocampus; Inhibitory Postsynaptic Potentials; Nerve Tissue Proteins; Neuronal Plasticity; Neurons; Quinoxalines; Rats; Rats, Wistar; Receptors, GABA; Sodium Channel Blockers; Synaptic Transmission; Tetrodotoxin; Valine | 2014 |
Traumatic brain injury induces rapid enhancement of cortical excitability in juvenile rats.
Topics: Animals; Animals, Newborn; Biophysics; Brain Injuries; Cerebral Cortex; Disease Models, Animal; Electric Stimulation; Electroencephalography; Epilepsy; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Neurons; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Sprague-Dawley; Valine | 2015 |
Subchronic glucocorticoid receptor inhibition rescues early episodic memory and synaptic plasticity deficits in a mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Dexamethasone; Disease Models, Animal; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glucocorticoids; Hippocampus; Hormone Antagonists; Humans; Memory Disorders; Memory, Episodic; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mifepristone; Mutation; Neuronal Plasticity; Quinoxalines; Receptors, Glucocorticoid; Recognition, Psychology; Valine | 2015 |
Cell-specific activity-dependent fractionation of layer 2/3→5B excitatory signaling in mouse auditory cortex.
Topics: Animals; Animals, Newborn; Auditory Cortex; Auditory Pathways; Excitatory Amino Acid Antagonists; Female; Flavoproteins; GABA Antagonists; In Vitro Techniques; Inferior Colliculi; Male; Mice; Mice, Inbred ICR; Models, Neurological; Nerve Net; Neurons; Patch-Clamp Techniques; Pyridazines; Quinoxalines; Synaptic Potentials; Valine | 2015 |
Seizure-related regulation of GABAA receptors in spontaneously epileptic rats.
Topics: Animals; Biotinylation; Disease Models, Animal; Excitatory Amino Acid Antagonists; GABA Agonists; Gene Expression Regulation; Hippocampus; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Isoxazoles; Male; Muscarinic Agonists; Neurons; Pilocarpine; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Status Epilepticus; Valine | 2015 |
Early adenosine release contributes to hypoxia-induced disruption of stimulus-induced sharp wave-ripple complexes in rat hippocampal area CA3.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Bicuculline; CA3 Region, Hippocampal; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; GABA-A Receptor Antagonists; Hypoxia; In Vitro Techniques; Nerve Net; Oxygen; Patch-Clamp Techniques; Pyramidal Cells; Quinoxalines; Rats; Rats, Wistar; Valine; Xanthines | 2015 |
μ-Opioid Receptor-Mediated Inhibition of Intercalated Neurons and Effect on Synaptic Transmission to the Central Amygdala.
Topics: Analgesics, Opioid; Animals; Central Amygdaloid Nucleus; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Excitatory Amino Acid Antagonists; Glutamate Decarboxylase; In Vitro Techniques; Mice; Mice, Inbred C57BL; Mice, Transgenic; Narcotic Antagonists; Neural Inhibition; Neurons; Peptides; Quinoxalines; Receptors, Opioid, mu; Sodium Channel Blockers; Synaptic Transmission; Tetrodotoxin; Valine | 2015 |
Early postnatal nicotine exposure disrupts the α2* nicotinic acetylcholine receptor-mediated control of oriens-lacunosum moleculare cells during adolescence in rats.
Topics: Age Factors; Animals; Animals, Newborn; Bicuculline; Excitatory Amino Acid Antagonists; Female; GABA-A Receptor Antagonists; Gene Expression Regulation, Developmental; Hippocampus; In Vitro Techniques; Interneurons; Long-Term Potentiation; Male; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Patch-Clamp Techniques; Pregnancy; Prenatal Exposure Delayed Effects; Quinoxalines; Rats; Rats, Sprague-Dawley; Valine | 2016 |
Dendritic Organization of Olfactory Inputs to Medial Amygdala Neurons.
Topics: Action Potentials; Afferent Pathways; Animals; Calcium; Central Nervous System Stimulants; Corticomedial Nuclear Complex; Dendrites; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamate Decarboxylase; In Vitro Techniques; Mice; Mice, Transgenic; Neurons; Olfactory Bulb; Patch-Clamp Techniques; Picrotoxin; Quinoxalines; Sodium Channel Blockers; Tetrodotoxin; Valine | 2015 |
Correlated Synaptic Inputs Drive Dendritic Calcium Amplification and Cooperative Plasticity during Clustered Synapse Development.
Topics: Age Factors; Animals; Animals, Newborn; Calcium; Calcium Signaling; Dendrites; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Indoles; Membrane Potentials; Neuronal Plasticity; Neurons; Quinoxalines; Rats; Rats, Sprague-Dawley; Synapses; Valine | 2016 |
Involvement of hippocampal NMDA receptors in retrieval of spontaneous object recognition memory in rats.
Topics: Analysis of Variance; Animals; Discrimination Learning; Excitatory Amino Acid Agents; Hippocampus; Male; Mental Recall; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Recognition, Psychology; Time Factors; Valine | 2016 |
Synchronized gamma-frequency inhibition in neocortex depends on excitatory-inhibitory interactions but not electrical synapses.
Topics: Action Potentials; Animals; Bacterial Proteins; Channelrhodopsins; Connexins; Excitatory Amino Acid Antagonists; Gamma Rhythm; Gap Junction delta-2 Protein; Interneurons; Luminescent Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Models, Neurological; Neocortex; Neural Inhibition; Parvalbumins; Pyramidal Cells; Quinoxalines; Somatostatin; Synapses; Synaptic Transmission; Valine | 2016 |
Dynamic balance of excitation and inhibition rapidly modulates spike probability and precision in feed-forward hippocampal circuits.
Topics: Action Potentials; Animals; Electric Stimulation; Excitatory Amino Acid Antagonists; Female; Fragile X Mental Retardation Protein; Hippocampus; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Models, Neurological; Nerve Net; Neural Inhibition; Neurons; Patch-Clamp Techniques; Quinoxalines; Synaptic Transmission; Valine | 2016 |
Inward rectifier K
Topics: Action Potentials; Adrenergic beta-1 Receptor Agonists; Animals; Animals, Newborn; Dobutamine; Drug Interactions; Excitatory Amino Acid Antagonists; GABA Agents; gamma-Aminobutyric Acid; Inhibitory Postsynaptic Potentials; Potassium Channels, Inwardly Rectifying; Prefrontal Cortex; Pyramidal Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic; Sodium Channel Blockers; Synaptic Transmission; Tetrodotoxin; Valine | 2017 |
Loss of M1 Receptor Dependent Cholinergic Excitation Contributes to mPFC Deactivation in Neuropathic Pain.
Topics: Acetylcholine; Action Potentials; Animals; Disease Models, Animal; Excitatory Amino Acid Antagonists; GABA Antagonists; Gene Expression Regulation; Hyperalgesia; Male; Pain Threshold; Picrotoxin; Prefrontal Cortex; Pyramidal Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M1; Sciatica; Subcellular Fractions; Synaptic Transmission; Valine | 2017 |
Mild Traumatic Brain Injury Induces Structural and Functional Disconnection of Local Neocortical Inhibitory Networks via Parvalbumin Interneuron Diffuse Axonal Injury.
Topics: Action Potentials; Animals; Brain Injuries, Traumatic; Diffuse Axonal Injury; Disease Models, Animal; Excitatory Amino Acid Antagonists; Glutamate Decarboxylase; Inhibitory Postsynaptic Potentials; Luminescent Proteins; Male; Mice; Mice, Transgenic; Neocortex; Nerve Tissue Proteins; Neural Inhibition; Neural Pathways; Parvalbumins; Quinoxalines; Valine; Vesicular Inhibitory Amino Acid Transport Proteins | 2018 |
Patient engagement and study design of PROP UP: A multi-site patient-centered prospective observational study of patients undergoing hepatitis C treatment.
Topics: Adult; Antiviral Agents; Benzimidazoles; Benzofurans; Carbamates; Drug Combinations; Female; Fluorenes; Hepatitis C, Chronic; Heterocyclic Compounds, 4 or More Rings; Humans; Imidazoles; Macrocyclic Compounds; Male; Patient Participation; Patient-Centered Care; Prospective Studies; Pyrrolidines; Quinoxalines; Ritonavir; Sofosbuvir; Sulfonamides; Treatment Outcome; Uracil; Uridine Monophosphate; Valine | 2017 |
Chronic salt-loading reduces basal excitatory input to CRH neurons in the paraventricular nucleus and accelerates recovery from restraint stress in male mice.
Topics: Animals; Area Under Curve; Corticotropin-Releasing Hormone; Drinking; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Luminescent Proteins; Male; Mice; Mice, Transgenic; Mutation; Neurons; Paraventricular Hypothalamic Nucleus; Patch-Clamp Techniques; Quinoxalines; Recovery of Function; Restraint, Physical; RNA, Messenger; Salts; Sodium; Time Factors; Valine | 2017 |
Nicotinic activity depresses synaptic potentiation in layer V pyramidal neurons of mouse insular cortex.
Topics: Acetylcholine; Animals; Animals, Newborn; Bicuculline; Cerebral Cortex; Cholinergic Agents; Dihydro-beta-Erythroidine; Excitatory Amino Acid Antagonists; Female; GABA-A Receptor Antagonists; Lysine; Male; Mice; Mice, Inbred C57BL; Neural Inhibition; Nicotine; Pyramidal Cells; Quinoxalines; Synaptic Potentials; Valine | 2017 |
Administrations of thalidomide into the rostral ventromedial medulla produce antinociceptive effects in a rat model of postoperative pain.
Topics: Analgesics; Animals; Disease Models, Animal; Electric Stimulation; Excitatory Amino Acid Antagonists; Hyperalgesia; Inhibitory Postsynaptic Potentials; Male; Medulla Oblongata; Neurons; Pain Measurement; Pain Threshold; Pain, Postoperative; Quinoxalines; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Tetrodotoxin; Thalidomide; Valine | 2018 |
Epigenetic control of epilepsy target genes contributes to a cellular memory of epileptogenesis in cultured rat hippocampal neurons.
Topics: Action Potentials; Animals; Animals, Newborn; Cells, Cultured; DNA Methylation; Epigenesis, Genetic; Epilepsy; Excitatory Amino Acid Agents; Gene Expression; Glutamic Acid; Hippocampus; Microtubule-Associated Proteins; Models, Biological; Neurons; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Sodium Channel Blockers; Tetrodotoxin; Valine | 2017 |
The C-terminal tails of endogenous GluA1 and GluA2 differentially contribute to hippocampal synaptic plasticity and learning.
Topics: Animals; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Hippocampus; Learning; Long-Term Potentiation; Long-Term Synaptic Depression; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neuronal Plasticity; Peptide Fragments; Protein Domains; Quinoxalines; Receptors, AMPA; Sodium Channel Blockers; Synapses; Tetrodotoxin; Valine | 2018 |
Mechanisms of Spontaneous Electrical Activity in the Developing Cerebral Cortex-Mouse Subplate Zone.
Topics: Action Potentials; Animals; Bicuculline; Calcium Channel Blockers; Calcium Signaling; Cerebral Cortex; Citrates; Connexin 26; Connexins; Ependymoglial Cells; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; Gadolinium; Gap Junction beta-1 Protein; Gap Junction delta-2 Protein; Gap Junctions; Glycine Agents; Hexachlorocyclohexane; Lanthanum; Mice; Neuroglia; Neurons; Octanols; Patch-Clamp Techniques; Probenecid; Pyridoxal Phosphate; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Strychnine; Valine; Vimentin | 2019 |
Noise-Induced Hypersensitization of the Acoustic Startle Response in Larval Zebrafish.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Electric Stimulation; Larva; Noise; Quinoxalines; Receptors, AMPA; Reflex, Startle; Valine; Zebrafish | 2018 |
Cost-Effectiveness of Elbasvir/Grazoprevir Versus Daclatasvir Plus Asunaprevir in Patients with Chronic Hepatitis C Virus Genotype 1b Infection in China.
Topics: Adult; Aged; Aged, 80 and over; Antiviral Agents; Benzofurans; Carbamates; China; Cohort Studies; Cost-Benefit Analysis; Drug Combinations; Drug Therapy, Combination; Female; Genotype; Hepatitis C, Chronic; Humans; Imidazoles; Isoquinolines; Male; Middle Aged; Pyrrolidines; Quinoxalines; Sulfonamides; Valine | 2018 |
The Successful Retreatment with Glecaprevir and Pibrentasvir of Genotype 1 or 2 HCV-infected Hemodialysis Patients who Failed to Respond to NS5A and Protease Inhibitor Treatment.
Topics: Aged; Aminoisobutyric Acids; Anti-Retroviral Agents; Antiviral Agents; Benzimidazoles; Carbamates; Cyclopropanes; Drug Therapy, Combination; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Imidazoles; Isoquinolines; Lactams, Macrocyclic; Leucine; Middle Aged; Proline; Protease Inhibitors; Pyrrolidines; Quinoxalines; Renal Dialysis; Retreatment; Sulfonamides; Treatment Failure; Valine | 2019 |
Patient-reported symptoms during and after direct-acting antiviral therapies for chronic hepatitis C: The PROP UP study.
Topics: 2-Naphthylamine; Adult; Aged; Aged, 80 and over; Amides; Anilides; Antiviral Agents; Benzimidazoles; Benzofurans; Carbamates; Cyclopropanes; Drug Therapy, Combination; Female; Fluorenes; Hepacivirus; Hepatitis C, Chronic; Heterocyclic Compounds, 4 or More Rings; Humans; Imidazoles; Lactams, Macrocyclic; Macrocyclic Compounds; Male; Middle Aged; Patient Reported Outcome Measures; Proline; Prospective Studies; Quinoxalines; Ritonavir; Sofosbuvir; Sulfonamides; Sustained Virologic Response; Uracil; Valine; Young Adult | 2019 |
Three Children Treated with Direct-acting Antivirals for Chronic Hepatitis C Virus Genotype 1b Infection.
Topics: Adolescent; Aminoisobutyric Acids; Anilides; Antiviral Agents; Benzimidazoles; Carbamates; Child; Cyclopropanes; Drug Therapy, Combination; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Lactams, Macrocyclic; Leucine; Macrocyclic Compounds; Proline; Pyrrolidines; Quinoxalines; Sulfonamides; Sustained Virologic Response; Treatment Outcome; Valine | 2020 |
English hepatitis C registry data show high response rates to directly acting anti-virals, even if treatment is not completed.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anilides; Antiviral Agents; Benzimidazoles; Benzofurans; Carbamates; Cyclopropanes; Drug Combinations; England; Female; Fluorenes; Hepatitis C; Humans; Imidazoles; Lactams, Macrocyclic; Macrocyclic Compounds; Male; Middle Aged; Proline; Quinoxalines; Registries; Ribavirin; Sofosbuvir; Sulfonamides; Sustained Virologic Response; Uridine Monophosphate; Valine; Young Adult | 2020 |
NMDARs contribute to the facial stimuli-evoked mossy fiber-granule cell synaptic transmission in vivo in mice.
Topics: Animals; Cerebellar Cortex; Excitatory Amino Acid Antagonists; Mice; Mice, Inbred ICR; N-Methylaspartate; Neurons; Physical Stimulation; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Valine; Vibrissae | 2020 |
Identification of microRNA associated with the elimination of hepatitis C virus genotype 1b by direct-acting antiviral therapies.
Topics: Amides; Antiviral Agents; Benzofurans; Biomarkers; Carbamates; Cyclopropanes; Disease Eradication; Drug Therapy, Combination; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Imidazoles; Isoquinolines; Male; MicroRNAs; Oligonucleotide Array Sequence Analysis; Pyrrolidines; Quinoxalines; Sulfonamides; Valine | 2021 |
Real-world effectiveness of direct-acting antiviral agents for chronic hepatitis C patients with genotype-2 infection after completed treatment.
Topics: Age Factors; Aged; Antiviral Agents; Benzimidazoles; Carbamates; Carcinoma, Hepatocellular; Drug Combinations; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; Heterocyclic Compounds, 4 or More Rings; Humans; Imidazoles; Liver Cirrhosis; Liver Neoplasms; Male; Middle Aged; Multivariate Analysis; Pyrrolidines; Quinoxalines; Retrospective Studies; Ribavirin; Sofosbuvir; Sulfonamides; Taiwan; Treatment Outcome; Valine | 2021 |
Effectiveness of direct-acting antivirals in maintenance hemodialysis patients complicated with chronic hepatitis C.
Topics: Alanine Transaminase; Amides; Antiviral Agents; Aspartate Aminotransferases; Benzofurans; Carbamates; Cyclopropanes; Drug Therapy, Combination; Female; Genotype; Hemoglobins; Hepacivirus; Hepatitis C, Chronic; Humans; Imidazoles; Isoquinolines; Male; Middle Aged; Pyrrolidines; Quinoxalines; Renal Dialysis; Renal Insufficiency, Chronic; Retrospective Studies; RNA, Viral; Sofosbuvir; Sulfonamides; Valine; Viral Load | 2020 |
Biochemical and structural characterization of quizalofop-resistant wheat acetyl-CoA carboxylase.
Topics: Acetyl-CoA Carboxylase; Acetyltransferases; Alanine; Amino Acid Substitution; Herbicide Resistance; Herbicides; Mutation; Plant Proteins; Poaceae; Propionates; Pyridines; Quinoxalines; Triticum; Valine | 2022 |