valine and oxazoles

valine has been researched along with oxazoles in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19909 (36.00)18.7374
1990's3 (12.00)18.2507
2000's10 (40.00)29.6817
2010's3 (12.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Berger, AE; Bhuyan, BK; Blowers, CL; Kuentzel, SL; Neil, GL1
McCammon, JA; Wade, RC2
Girdlestone, D; Thomson, AM; West, DC1
Clifford, DB; Todd, RD; Zorumski, CF1
King, AE; Nistri, A; Rovira, C1
Stein, HH; Yellin, TO1
Cain, DF1
Curtis, DR; Hansen, JJ; Krogsgaard-Larsen, P; Lauridsen, J; Leah, JD; Peet, MJ1
Collins, JF; Parks, DA; Schwarcz, R1
Eng, P; Hösli, E; Hösli, L; Lehmann, R1
Fukunaga, K; Miyamoto, E; Muller, D; Stoppini, L1
Crump, CE; Hayden, FG; Kaiser, L1
Turner, RB1
Gersten, M; Hsyu, PH; Kerr, BM; Penning, CA; Pithavala, YK1
Chi-Burris, K; Gersten, M; Gwaltney, JM; Hayden, FG; Hsyu, P; Patick, AK; Smith, GJ; Turner, RB; Zalman, LS1
Agostini, M; Chatterjee, VK; Garnes, KT; Gurnell, M; Levinson, SH; O'Rahilly, S; Rajanayagam, O; Savage, DB; Schwabe, JW; Smith, AG; Willson, TM; Wood, EM; Xu, HE1
Bertram, A; Maulucci, N; Mohd Nor, SM; New, OM; Pattenden, G1
Tao, J; Zhao, L1
Moreira, R; Santos, MM1
Molinski, TF; Pigza, JA; Quach, T1
Beaudet, I; Coeffard, V; Evain, M; Le Grognec, E; Quintard, JP1
Aguayo, E; Birkus, G; Cihlar, T; Jordan, R; Lee, G; Mello, C; Rodriguez, M1
Borduas-Dedekind, N; Lau, K; Manfrin, A; McNeill, K1
Lv, W; Wang, Y; Zhang, M; Zhang, Y1

Reviews

3 review(s) available for valine and oxazoles

ArticleYear
The treatment of rhinovirus infections: progress and potential.
    Antiviral research, 2001, Volume: 49, Issue:1

    Topics: 3C Viral Proteases; Antiviral Agents; Clinical Trials as Topic; Combined Modality Therapy; Common Cold; Cysteine Endopeptidases; Dietary Supplements; Drug Therapy, Combination; Echinacea; Enzyme Inhibitors; Histamine H1 Antagonists; Humans; Intercellular Adhesion Molecule-1; Isoxazoles; Oxadiazoles; Oxazoles; Phenylalanine; Phytotherapy; Picornaviridae Infections; Plant Extracts; Plants, Medicinal; Pyrrolidinones; Receptors, Virus; Rhinovirus; Valine; Viral Proteins; Zinc

2001
An integrated approach to developing chemoenzymatic processes at the industrial scale.
    Ernst Schering Foundation symposium proceedings, 2006, Issue:3

    Topics: Bacillus; Biotechnology; Biotransformation; Catalysis; Chemistry, Pharmaceutical; Cost-Benefit Analysis; Drug Design; Enzymes; Fructose-Bisphosphate Aldolase; HIV Protease Inhibitors; Isoxazoles; Models, Chemical; Models, Theoretical; Oxazoles; Pharmaceutical Preparations; Phenylalanine; Pyrrolidines; Pyrrolidinones; Stereoisomerism; Valine

2006
Michael acceptors as cysteine protease inhibitors.
    Mini reviews in medicinal chemistry, 2007, Volume: 7, Issue:10

    Topics: Animals; Cysteine Proteinase Inhibitors; Drug Design; Humans; Isoxazoles; Leucine; Molecular Structure; Oxazoles; Peptides; Phenylalanine; Pyrrolidines; Pyrrolidinones; Structure-Activity Relationship; Sulfones; Valine

2007

Trials

2 trial(s) available for valine and oxazoles

ArticleYear
Pharmacokinetics and safety of an antirhinoviral agent, ruprintrivir, in healthy volunteers.
    Antimicrobial agents and chemotherapy, 2002, Volume: 46, Issue:2

    Topics: Adult; Antiviral Agents; Double-Blind Method; Humans; Isoxazoles; Male; Middle Aged; Oxazoles; Phenylalanine; Pyrrolidines; Pyrrolidinones; Rhinovirus; Valine

2002
Phase II, randomized, double-blind, placebo-controlled studies of ruprintrivir nasal spray 2-percent suspension for prevention and treatment of experimentally induced rhinovirus colds in healthy volunteers.
    Antimicrobial agents and chemotherapy, 2003, Volume: 47, Issue:12

    Topics: Administration, Inhalation; Adolescent; Adult; Antiviral Agents; Biological Availability; Common Cold; Double-Blind Method; Endpoint Determination; Female; Humans; Isoxazoles; Male; Middle Aged; Mucus; Oxazoles; Phenylalanine; Pyrrolidines; Pyrrolidinones; Rhinovirus; Suspensions; Valine

2003

Other Studies

20 other study(ies) available for valine and oxazoles

ArticleYear
Studies of the biochemical pharmacology of the fermentation-derived antitumor agent, (alpha S, 5S)-alpha-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid (AT-125).
    Advances in enzyme regulation, 1978, Volume: 17

    Topics: Animals; Antibiotics, Antineoplastic; Cell Division; Cell Line; Cell Survival; Female; Glutamine; Glycine; Isoxazoles; Leukemia L1210; Leukemia P388; Macromolecular Substances; Male; Mice; Oxazoles; Sex Factors; Thymidine; Uridine; Valine

1978
Binding of an antiviral agent to a sensitive and a resistant human rhinovirus. Computer simulation studies with sampling of amino acid side-chain conformation. I. Mapping the rotamers of residue 188 of viral protein 1.
    Journal of molecular biology, 1992, Jun-05, Volume: 225, Issue:3

    Topics: Antiviral Agents; Computer Simulation; Crystallography; Drug Resistance, Microbial; Leucine; Molecular Structure; Motion; Oxazoles; Protein Conformation; Rhinovirus; Thermodynamics; Valine; Viral Proteins

1992
Binding of an antiviral agent to a sensitive and a resistant human rhinovirus. Computer simulation studies with sampling of amino acid side-chain conformations. II. Calculation of free-energy differences by thermodynamic integration.
    Journal of molecular biology, 1992, Jun-05, Volume: 225, Issue:3

    Topics: Antiviral Agents; Computer Simulation; Crystallography; Drug Resistance, Microbial; Leucine; Models, Molecular; Motion; Oxazoles; Rhinovirus; Structure-Activity Relationship; Thermodynamics; Valine; Viral Proteins; Water

1992
A local circuit neocortical synapse that operates via both NMDA and non-NMDA receptors.
    British journal of pharmacology, 1989, Volume: 96, Issue:2

    Topics: 2-Amino-5-phosphonovalerate; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Aspartic Acid; Cerebral Cortex; Dipeptides; Electric Stimulation; Female; Ibotenic Acid; In Vitro Techniques; N-Methylaspartate; Neural Conduction; Oxazoles; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses; Valine

1989
Complex responses activated by ibotenate in postnatal rat hippocampal neurons.
    Brain research, 1989, Aug-07, Volume: 494, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Cells, Cultured; Hippocampus; Ibotenic Acid; Oxazoles; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine

1989
The excitation of frog motoneurones in vitro by the glutamate analogue, DI-alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA), and the effect of amino acid antagonists.
    Neuroscience letters, 1985, Mar-22, Volume: 55, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; 2-Aminoadipic Acid; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids, Dicarboxylic; Animals; Glutamates; Glutamic Acid; Ibotenic Acid; Membrane Potentials; Motor Neurons; Oxadiazoles; Oxazoles; Quisqualic Acid; Rana temporaria; Receptors, AMPA; Receptors, Drug; Spinal Cord; Synapses; Synaptic Transmission; Valine

1985
Pemoline and magnesium hydroxide: lack of effect on RNA and protein synthesis.
    Science (New York, N.Y.), 1967, Jul-07, Volume: 157, Issue:3784

    Topics: Animals; Brain; Carcinoma, Ehrlich Tumor; Central Nervous System Stimulants; Hydroxides; In Vitro Techniques; Leucine; Magnesium; Neoplasm Proteins; Nucleotidyltransferases; Oxazoles; Pemoline; Rats; RNA, Neoplasm; Uridine; Valine

1967
Lack of effect of pemoline on the incorporation of [3H] uridine into RNA in brain slices.
    Life sciences, 1967, Sep-15, Volume: 6, Issue:18

    Topics: Animals; Brain Chemistry; Carbon Isotopes; Guinea Pigs; In Vitro Techniques; Magnesium; Oxazoles; Pemoline; RNA; Tritium; Uridine; Valine

1967
Glutamic acid agonists. Stereochemical and conformational studies of DL-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) and related compounds.
    Neuroscience letters, 1982, Aug-31, Volume: 31, Issue:3

    Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cats; Evoked Potentials; Ganglia, Spinal; Glutamates; Glutamic Acid; Ibotenic Acid; Interneurons; Oxazoles; Spinal Cord; Stereoisomerism; Synaptic Transmission; Valine

1982
alpha-Amino-omega-phosphono carboxylates block ibotenate but not kainate neurotoxicity in rat hippocampus.
    Neuroscience letters, 1982, Nov-16, Volume: 33, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Brain Diseases; Hippocampus; Ibotenic Acid; Kainic Acid; Male; Neurotoxins; Oxazoles; Pyrrolidines; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Valine

1982
Effects of the glutamate analogue AMPA and its interaction with antagonists on cultured rat spinal and brain stem neurones.
    Neuroscience letters, 1983, Mar-28, Volume: 36, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Brain Stem; Cells, Cultured; Embryo, Mammalian; Glutamates; Ibotenic Acid; N-Methylaspartate; Oxazoles; Rats; Receptors, Cell Surface; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Valine

1983
Long-term potentiation is associated with an increased activity of Ca2+/calmodulin-dependent protein kinase II.
    The Journal of biological chemistry, 1993, Apr-15, Volume: 268, Issue:11

    Topics: Animals; Animals, Newborn; Calcium-Calmodulin-Dependent Protein Kinases; Electric Stimulation; Evoked Potentials; Hippocampus; Kinetics; Male; Marine Toxins; Neurons; Organ Culture Techniques; Oxazoles; Phosphoprotein Phosphatases; Protein Kinases; Pyramidal Tracts; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Valine

1993
In vitro activity of pleconaril and AG7088 against selected serotypes and clinical isolates of human rhinoviruses.
    Antiviral research, 2000, Volume: 47, Issue:3

    Topics: Antiviral Agents; Cell Survival; Cells, Cultured; Common Cold; Humans; Isoxazoles; Oxadiazoles; Oxazoles; Phenylalanine; Pyrrolidinones; Reverse Transcriptase Polymerase Chain Reaction; Rhinovirus; Spectrophotometry; Valine

2000
Tyrosine agonists reverse the molecular defects associated with dominant-negative mutations in human peroxisome proliferator-activated receptor gamma.
    Endocrinology, 2004, Volume: 145, Issue:4

    Topics: Amino Acid Sequence; Cell Line; Gene Expression; Genes, Dominant; Humans; Leucine; Ligands; Methionine; Models, Structural; Molecular Sequence Data; Monocytes; Mutation; Oxazoles; Pioglitazone; Proline; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Thiazolidinediones; Transcription Factors; Transfection; Tyrosine; Valine

2004
Synthesis of libraries of thiazole, oxazole and imidazole-based cyclic peptides from azole-based amino acids. A new synthetic approach to bistratamides and didmolamides.
    Organic & biomolecular chemistry, 2007, May-21, Volume: 5, Issue:10

    Topics: Alanine; Amino Acids; Animals; Chemistry, Organic; Chemistry, Pharmaceutical; Imidazoles; Models, Chemical; Oxazoles; Peptides, Cyclic; Thiazoles; Urochordata; Valine

2007
Oxazoline-oxazinone oxidative rearrangement. divergent syntheses of (2S,3S)-4,4,4-trifluorovaline and (2S,4S)-5,5,5-Trifluoroleucine.
    The Journal of organic chemistry, 2009, Aug-07, Volume: 74, Issue:15

    Topics: Leucine; Molecular Conformation; Oxazines; Oxazoles; Oxidation-Reduction; Stereoisomerism; Valine

2009
Synthesis of highly enantioenriched chiral alpha-aminoorganotins via diastereoselective ring opening of chiral N-(arenesulfonyl) 2-tributylstannyloxazolidines.
    The Journal of organic chemistry, 2009, Aug-21, Volume: 74, Issue:16

    Topics: Ethanolamines; Glycine; Nitrogen; Organotin Compounds; Oxazoles; Propanolamines; Stereoisomerism; Substrate Specificity; Valine

2009
Multiple classes of antiviral agents exhibit in vitro activity against human rhinovirus type C.
    Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:3

    Topics: Antiviral Agents; Common Cold; Dose-Response Relationship, Drug; HeLa Cells; Humans; In Vitro Techniques; Isoxazoles; Oxadiazoles; Oxazoles; Phenylalanine; Piperidines; Pyridazines; Pyrrolidinones; Replicon; Rhinovirus; RNA, Viral; Tubercidin; Valine; Virus Replication

2014
Singlet Oxygen Photooxidation of Peptidic Oxazoles and Thiazoles.
    The Journal of organic chemistry, 2019, 03-01, Volume: 84, Issue:5

    Topics: Kinetics; Oxazoles; Oxidation-Reduction; Peptides; Peptides, Cyclic; Photochemical Processes; Singlet Oxygen; Thiazoles; Valine

2019
Automated cell-based luminescence assay for profiling antiviral compound activity against enteroviruses.
    Scientific reports, 2019, 04-15, Volume: 9, Issue:1

    Topics: Animals; Antiviral Agents; Chlorocebus aethiops; Cytopathogenic Effect, Viral; Enterovirus; Enterovirus Infections; HeLa Cells; Humans; Isoxazoles; Luminescent Measurements; Microbial Sensitivity Tests; Oxadiazoles; Oxazoles; Phenylalanine; Pyrrolidinones; Valine; Vero Cells

2019