Compounds > valine

valine and nelfinavir

valine has been researched along with nelfinavir in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (33.33)18.2507
2000's4 (66.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cammack, N; Chirn, GW; Craig, C; Dissanayeke, S; Duncan, IB; Gilbert, S; Moffatt, A; Race, E; Rose, J; Sheldon, J; Whittaker, L1
Freire, E; Luque, I; Todd, MJ; Velázquez-Campoy, A1
Blum, LE; Clemente, JC; Dunn, BM; Goodenow, MM; Hemrajani, R1
Birnböck, H; Götschi, A; Lavé, T; Pähler, A; Ramp, T1
Gocke, E; Grimm, HP; Lavé, T; Müller, L; Paehler, A1

Other Studies

6 other study(ies) available for valine and nelfinavir

ArticleYear
HIV protease genotype and viral sensitivity to HIV protease inhibitors following saquinavir therapy.
    AIDS (London, England), 1998, Sep-10, Volume: 12, Issue:13

    Topics: Amino Acid Substitution; Carbamates; Clinical Trials as Topic; Databases, Factual; DNA, Viral; Furans; Genetic Linkage; Genotype; HIV Infections; HIV Protease; HIV Protease Inhibitors; Humans; Indinavir; Methionine; Nelfinavir; Phenotype; Polymerase Chain Reaction; Ritonavir; Saquinavir; Sulfonamides; Valine

1998
Thermodynamic basis of resistance to HIV-1 protease inhibition: calorimetric analysis of the V82F/I84V active site resistant mutant.
    Biochemistry, 2000, Oct-03, Volume: 39, Issue:39

    Topics: Amino Acid Substitution; Binding Sites; Binding, Competitive; Calorimetry, Differential Scanning; Drug Resistance, Microbial; Entropy; Enzyme Stability; HIV Protease; HIV Protease Inhibitors; HIV-1; Indinavir; Mutagenesis, Site-Directed; Nelfinavir; Phenylalanine; Protons; Ritonavir; Saquinavir; Thermodynamics; Valine

2000
Protease inhibitor trials moving to next phase.
    AIDS alert, 1995, Volume: 10, Issue:8

    Topics: Antiviral Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Drug Therapy, Combination; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Isoquinolines; Nelfinavir; Quinolines; Ritonavir; Saquinavir; Stavudine; Thiazoles; Valine; Virus Replication

1995
Secondary mutations M36I and A71V in the human immunodeficiency virus type 1 protease can provide an advantage for the emergence of the primary mutation D30N.
    Biochemistry, 2003, Dec-30, Volume: 42, Issue:51

    Topics: Alanine; Anti-HIV Agents; Asparagine; Aspartic Acid; Binding Sites; Drug Resistance, Viral; HIV Protease; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Isoleucine; Kinetics; Methionine; Mutagenesis, Site-Directed; Nelfinavir; Ritonavir; Valine

2003
In vivo and in vitro characterization of ethyl methanesulfonate pharmacokinetics in animals and in human.
    Toxicology letters, 2009, Nov-12, Volume: 190, Issue:3

    Topics: Alkylating Agents; Animals; Dose-Response Relationship, Drug; Drug Contamination; Ethyl Methanesulfonate; Half-Life; Hemoglobins; HIV Protease Inhibitors; Humans; Macaca fascicularis; Male; Mice; Microsomes, Liver; Mutagens; Nelfinavir; Rats; Risk Assessment; Species Specificity; Tablets; Valine

2009
Modelling of patient EMS exposure: translating pharmacokinetics of EMS in vitro and in animals into patients.
    Toxicology letters, 2009, Nov-12, Volume: 190, Issue:3

    Topics: Alkylating Agents; Animals; Area Under Curve; Computer Simulation; Dose-Response Relationship, Drug; Drug Contamination; Ethyl Methanesulfonate; Hemoglobins; HIV Protease Inhibitors; Humans; In Vitro Techniques; Macaca fascicularis; Mice; Microsomes, Liver; Models, Biological; Mutagens; Nelfinavir; Rats; Risk Assessment; Species Specificity; Valine

2009