valine and methotrexate

valine has been researched along with methotrexate in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19904 (25.00)18.7374
1990's2 (12.50)18.2507
2000's3 (18.75)29.6817
2010's7 (43.75)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benkovic, SJ; Singh, UC1
Hill, JM; Hill, NO; Khan, A; Loeb, E; MacLellan, A; Roberts, J; Shields, WF1
Bernard, J; Boiron, M; Bussel, A; Dreyfus, B; Jacquillat, C; Larrieu, MJ; Loisel, JP; Rouesse, T; Weil, M1
Mørland, J; Vonen, B1
Kuntz, ID; Roe, DC1
Cohen, NC; Tschinke, V1
Croxford, R; Kim, YI; Lucock, M; Sohn, KJ; Yates, Z1
Prati, C; Streit, G; Toussirot, E; Wendling, D1
Al Qahtani, M; Alzahrani, M; Haider, A; Palker, V; Saeed, AB; Salih, SB1
Bouafia, F; Franchon, E; Gouraud, A; Pham, BN; Ranchon, F; Rioufol, C; Salles, G; Schwiertz, V; Vantard, N; Vial, T; You, B1
Cropley, T; Erdag, G; Lockman, D; Patterson, JW; Tromberg, J1
Boyd, AS; Miller, JL; Zwerner, JP1
Genovese, MC; Kinnman, N; Pacheco-Tena, C; van Vollenhoven, RF; Zhang, Y1
Gadina, M; O'Shea, JJ; Schwartz, DM1
Aeschlimann, F; Baer, W; Berthet, G; Cannizzaro, E; Heininger, U; Hofer, M; Kaiser, D; Leuvenink, R; Schroeder, S; Woerner, A1
Dora, CP; Jain, S; Katiyar, SS; Kushwah, V1

Trials

2 trial(s) available for valine and methotrexate

ArticleYear
Response to highly purified L-asparaginase during therapy of acute leukemia.
    Cancer research, 1969, Volume: 29, Issue:8

    Topics: Adolescent; Adult; Asparaginase; Carbon Isotopes; Child; Child, Preschool; Clinical Trials as Topic; Female; Hematopoiesis; Humans; Injections, Intravenous; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Methotrexate; Valine

1969
VX-509 (Decernotinib), an Oral Selective JAK-3 Inhibitor, in Combination With Methotrexate in Patients With Rheumatoid Arthritis.
    Arthritis & rheumatology (Hoboken, N.J.), 2016, Volume: 68, Issue:1

    Topics: Administration, Oral; Adult; Aged; Alanine Transaminase; Antirheumatic Agents; Arthritis, Rheumatoid; Aspartate Aminotransferases; Cholesterol, HDL; Cholesterol, LDL; Creatinine; Double-Blind Method; Drug Therapy, Combination; Female; Headache; Heterocyclic Compounds, 2-Ring; Humans; Janus Kinase 3; Male; Methotrexate; Middle Aged; Treatment Outcome; Valine; Young Adult

2016

Other Studies

14 other study(ies) available for valine and methotrexate

ArticleYear
A free-energy perturbation study of the binding of methotrexate to mutants of dihydrofolate reductase.
    Proceedings of the National Academy of Sciences of the United States of America, 1988, Volume: 85, Issue:24

    Topics: Binding Sites; Chemical Phenomena; Chemistry, Physical; Computer Simulation; Methotrexate; Mutation; Phenylalanine; Tetrahydrofolate Dehydrogenase; Tyrosine; Valine

1988
Treatment of acute leukemia with L-asparaginase--preliminary results on 84 cases.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1970, Volume: 33

    Topics: Acute Disease; Asparaginase; Asparagine; Blood Coagulation Disorders; Cells, Cultured; Central Nervous System Diseases; Chemical and Drug Induced Liver Injury; Daunorubicin; Humans; Kidney Diseases; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Liver Function Tests; Methotrexate; Prednisone; Valine; Vincristine

1970
Isolated rat hepatocytes in suspension: potential hepatotoxic effects of six different drugs.
    Archives of toxicology, 1984, Volume: 56, Issue:1

    Topics: Acetaminophen; Adenosine Triphosphate; Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Cell Survival; Chemical and Drug Induced Liver Injury; Ethanol; Fentanyl; In Vitro Techniques; L-Lactate Dehydrogenase; Liver; Methotrexate; Oxytetracycline; Protein Biosynthesis; Rats; Valine

1984
BUILDER v.2: improving the chemistry of a de novo design strategy.
    Journal of computer-aided molecular design, 1995, Volume: 9, Issue:3

    Topics: Algorithms; Binding Sites; Databases, Factual; Drug Design; Evaluation Studies as Topic; HIV Protease Inhibitors; Methotrexate; Models, Chemical; Molecular Structure; Software; Sugar Alcohols; Valine

1995
The NEWLEAD program: a new method for the design of candidate structures from pharmacophoric hypotheses.
    Journal of medicinal chemistry, 1993, Nov-26, Volume: 36, Issue:24

    Topics: Algorithms; Computer Simulation; Drug Design; HIV Protease Inhibitors; Indomethacin; Methotrexate; Models, Molecular; Molecular Structure; Software; Sugar Alcohols; Valine

1993
Effect of the methylenetetrahydrofolate reductase C677T polymorphism on chemosensitivity of colon and breast cancer cells to 5-fluorouracil and methotrexate.
    Journal of the National Cancer Institute, 2004, Jan-21, Volume: 96, Issue:2

    Topics: Alanine; Animals; Antimetabolites, Antineoplastic; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Colonic Neoplasms; Cytosine; DNA Probes; Female; Fluorouracil; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Genotype; Humans; Leucovorin; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred BALB C; Polymorphism, Genetic; Random Allocation; Thymidylate Synthase; Thymine; Transfection; Transplantation, Heterologous; Valine

2004
Herpes zoster in patients taking TNFalpha antagonists for chronic inflammatory joint disease.
    Joint bone spine, 2008, Volume: 75, Issue:5

    Topics: Acyclovir; Adalimumab; Adult; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Antiviral Agents; Arthritis, Rheumatoid; Drug Therapy, Combination; Etanercept; Female; Glucocorticoids; Herpes Zoster; Humans; Immunoglobulin G; Immunosuppressive Agents; Infliximab; Male; Methotrexate; Middle Aged; Receptors, Tumor Necrosis Factor; Retrospective Studies; Risk Factors; Spondylitis, Ankylosing; Tumor Necrosis Factor-alpha; Valacyclovir; Valine

2008
Primary CNS lymphoma presenting as fever of unknown origin.
    Journal of neuro-oncology, 2009, Volume: 93, Issue:3

    Topics: Antihypertensive Agents; Antineoplastic Agents; Antitubercular Agents; Aspirin; Brain Neoplasms; Cranial Irradiation; Diagnosis, Differential; Fatal Outcome; Fever of Unknown Origin; Humans; Hypertension; Indapamide; Lymphoma; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Tetrazoles; Tuberculosis; Valine; Valsartan

2009
Suspicion of drug-drug interaction between high-dose methotrexate and proton pump inhibitors: a case report - should the practice be changed?
    Chemotherapy, 2011, Volume: 57, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acyclovir; Antimetabolites, Antineoplastic; Antiviral Agents; Drug Interactions; Female; Fluoxetine; Humans; Methotrexate; Middle Aged; Pantoprazole; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Proton Pump Inhibitors; Renal Insufficiency; Valacyclovir; Valine

2011
A case of pityriasis rubra pilaris with associated focal acantholytic dyskeratosis complicated by Kaposi's varicelliform eruption.
    Journal of cutaneous pathology, 2011, Volume: 38, Issue:11

    Topics: Acantholysis; Acyclovir; Aged; Antiviral Agents; Darier Disease; Diagnosis, Differential; Herpes Simplex; Humans; Ichthyosis; Kaposi Varicelliform Eruption; Male; Methotrexate; Pityriasis Rubra Pilaris; Valacyclovir; Valine

2011
Herpes simplex virus-induced plasmacytic atypia.
    Journal of cutaneous pathology, 2012, Volume: 39, Issue:2

    Topics: Acyclovir; Adult; Antiviral Agents; Dermatologic Agents; Female; Herpes Simplex; Herpesvirus 1, Human; Herpesvirus 2, Human; Humans; Methotrexate; Pemphigus; Perineum; Plasma Cells; Prednisolone; Skin; Skin Diseases; Ulcer; Valacyclovir; Valine

2012
Decernotinib: A Next-Generation Jakinib.
    Arthritis & rheumatology (Hoboken, N.J.), 2016, Volume: 68, Issue:1

    Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Female; Heterocyclic Compounds, 2-Ring; Humans; Male; Methotrexate; Valine

2016
Clinical course and therapeutic approach to varicella zoster virus infection in children with rheumatic autoimmune diseases under immunosuppression.
    Pediatric rheumatology online journal, 2016, Jun-02, Volume: 14, Issue:1

    Topics: Acyclovir; Adolescent; Antirheumatic Agents; Antiviral Agents; Arthritis, Juvenile; Chickenpox; Child; Child, Preschool; Etanercept; Female; Herpes Zoster; Humans; Immunocompromised Host; Immunosuppressive Agents; Isoxazoles; Leflunomide; Male; Methotrexate; Retrospective Studies; Treatment Outcome; Valacyclovir; Valine; Young Adult

2016
Novel biosurfactant and lipid core-shell type nanocapsular sustained release system for intravenous application of methotrexate.
    International journal of pharmaceutics, 2019, Feb-25, Volume: 557

    Topics: Administration, Intravenous; Animals; Antineoplastic Agents; Cell Survival; Delayed-Action Preparations; Drug Liberation; Erythrocytes; Female; Hemolysis; Humans; Lipids; MCF-7 Cells; Methotrexate; Mice; Nanoparticles; Neoplasms; Rats, Sprague-Dawley; Surface-Active Agents; Tumor Burden; Valine

2019