Compounds > valine

valine and dabrafenib

valine has been researched along with dabrafenib in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's8 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Clements, A; Kefford, RF; Klein, O; Long, GV; Menzies, AM; O'Toole, S1
Dudek, AZ; Elmquist, WF; Mittapalli, RK; Vaidhyanathan, S1
Busser, B; Charles, J; de Fraipont, F; Leccia, MT; Martel, C; Robert, C1
Allan, RW; Drane, WE; Ivey, AM; Kaye, FJ; Mendenhall, WM1
Aktan, G; Amonkar, MM; Arance, A; Bondarenko, I; Casey, M; Chiarion-Sileni, V; de Braud, F; DeMarini, DJ; Flaherty, KT; Garbe, C; Gogas, H; Grob, JJ; Irani, JG; Larkin, J; Lebbe, C; Levchenko, E; Long, GV; Mandalà, M; Millward, M; Nathan, P; Ribas, A; Robert, C; Schadendorf, D; Stroyakovskiy, D1
Abedalthagafi, M; Barker, FG; Brastianos, PK; Cahill, DP; Curry, WT; Dunn, IF; Frederick, DT; Getz, G; Gill, CM; Jones, PS; Louis, DN; Nahed, BV; Nayyar, N; Panka, DJ; Romero, JM; Santagata, S; Shankar, GM; Sullivan, RJ; Taylor-Weiner, A1
Chamberlain, MC1
Benedict, JJ; DeConti, R; Gibney, GT; Gonzalez, RJ; Kudchadkar, RR; McCardle, T; Messina, JL; Sloot, S; Smalley, KS; Sondak, VK; Turner, LM; Weber, JS; Zager, JS1

Reviews

1 review(s) available for valine and dabrafenib

ArticleYear
[Mechanisms of resistance to anti-BRAF treatments].
    Annales de dermatologie et de venereologie, 2014, Volume: 141, Issue:11

    Topics: Antineoplastic Agents; Drug Resistance, Neoplasm; Humans; Imidazoles; Indoles; Melanoma; Molecular Targeted Therapy; Mutation; Oximes; Proto-Oncogene Proteins B-raf; Sulfonamides; Valine; Vemurafenib

2014

Trials

1 trial(s) available for valine and dabrafenib

ArticleYear
Health-related quality of life impact in a randomised phase III study of the combination of dabrafenib and trametinib versus dabrafenib monotherapy in patients with BRAF V600 metastatic melanoma.
    European journal of cancer (Oxford, England : 1990), 2015, Volume: 51, Issue:7

    Topics: Amino Acid Substitution; Antineoplastic Combined Chemotherapy Protocols; Health Status; Humans; Imidazoles; Melanoma; Neoplasm Metastasis; Oximes; Pain Measurement; Proto-Oncogene Mas; Proto-Oncogene Proteins B-raf; Pyridones; Pyrimidinones; Quality of Life; Skin Neoplasms; Valine

2015

Other Studies

6 other study(ies) available for valine and dabrafenib

ArticleYear
BRAF inhibitor activity in V600R metastatic melanoma.
    European journal of cancer (Oxford, England : 1990), 2013, Volume: 49, Issue:5

    Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Amino Acid Substitution; Antineoplastic Agents; Arginine; Compassionate Use Trials; Female; Humans; Imidazoles; Male; Melanoma; Middle Aged; Mutation, Missense; Neoplasm Metastasis; Oximes; Protein Kinase Inhibitors; Proto-Oncogene Proteins B-raf; Skin Neoplasms; Valine; Young Adult

2013
Mechanisms limiting distribution of the threonine-protein kinase B-RaF(V600E) inhibitor dabrafenib to the brain: implications for the treatment of melanoma brain metastases.
    The Journal of pharmacology and experimental therapeutics, 2013, Volume: 344, Issue:3

    Topics: Animals; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Blood-Brain Barrier; Brain Neoplasms; Cell Line; Dogs; Imidazoles; Indoles; Madin Darby Canine Kidney Cells; Melanoma; Mice; Mice, Knockout; Oximes; Pilot Projects; Proto-Oncogene Proteins B-raf; Sulfonamides; Valine; Vemurafenib

2013
Clinical and radiographic response with combined BRAF-targeted therapy in stage 4 ameloblastoma.
    Journal of the National Cancer Institute, 2015, Volume: 107, Issue:1

    Topics: Adult; Ameloblastoma; Antineoplastic Combined Chemotherapy Protocols; Black or African American; Compassionate Use Trials; Glutamic Acid; Humans; Imidazoles; Lung Neoplasms; Male; Mandibular Neoplasms; Molecular Targeted Therapy; Mutation; Neoplasm Recurrence, Local; Neoplasm Staging; Oximes; Proto-Oncogene Proteins B-raf; Pyridones; Pyrimidinones; Radiography; Treatment Outcome; Valine

2015
Dramatic Response of BRAF V600E Mutant Papillary Craniopharyngioma to Targeted Therapy.
    Journal of the National Cancer Institute, 2016, Volume: 108, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Craniopharyngioma; Craniotomy; Cytoreduction Surgical Procedures; Drug Administration Schedule; Glutamic Acid; Humans; Imidazoles; Magnetic Resonance Imaging; Male; Molecular Targeted Therapy; Mutation; Neoplasm Recurrence, Local; Neoplasm, Residual; Oximes; Pituitary Neoplasms; Protein Kinase Inhibitors; Proto-Oncogene Proteins B-raf; Pyridones; Pyrimidinones; Treatment Outcome; Valine

2016
Recurrent ganglioglioma in adults treated with BRAF inhibitors.
    CNS oncology, 2016, Volume: 5, Issue:1

    Topics: Adult; Brain Neoplasms; Enzyme Inhibitors; Female; Ganglioglioma; Glutamic Acid; Humans; Imidazoles; Male; Middle Aged; Mutation; Oximes; Proto-Oncogene Proteins B-raf; Valine

2016
BRAF inhibition for advanced locoregional BRAF V600E mutant melanoma: a potential neoadjuvant strategy.
    Melanoma research, 2016, Volume: 26, Issue:1

    Topics: Amino Acid Substitution; Antineoplastic Combined Chemotherapy Protocols; Disease Progression; Female; Follow-Up Studies; Glutamic Acid; Humans; Imidazoles; Indoles; Male; Melanoma; Middle Aged; Molecular Targeted Therapy; Mutation, Missense; Neoadjuvant Therapy; Oximes; Protein Kinase Inhibitors; Proto-Oncogene Proteins B-raf; Pyridones; Pyrimidinones; Retrospective Studies; Skin Neoplasms; Sulfonamides; Treatment Outcome; Valine; Vemurafenib

2016